Motif ID: GGAAGAC

Z-value: 1.112


Mature miRNA associated with seed GGAAGAC:

NamemiRBase Accession
hsa-miR-7 MIMAT0000252



Activity profile for motif GGAAGAC.

activity profile for motif GGAAGAC


Sorted Z-values histogram for motif GGAAGAC

Sorted Z-values for motif GGAAGAC



Network of associatons between targets according to the STRING database.



First level regulatory network of GGAAGAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_159141376 2.632 NM_021189
NM_001127173
CADM3

cell adhesion molecule 3

chr5_-_111093251 1.718 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr5_-_111312522 1.717 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr12_-_47219734 1.711 NM_001143824
NM_018018
SLC38A4

solute carrier family 38, member 4

chr5_-_111093030 1.704 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr5_-_111092918 1.690 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr5_-_111093792 1.677 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr1_+_89990396 1.657 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr1_+_90024271 1.420 NM_015350
LRRC8B
leucine rich repeat containing 8 family, member B
chr11_-_70935807 1.147 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr11_-_70507911 1.138 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr14_-_89883306 1.137 NM_005197
FOXN3
forkhead box N3
chr5_-_111091947 0.989 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr14_-_92414004 0.979 NM_006329
FBLN5
fibulin 5
chr14_-_90085325 0.963 NM_001085471
FOXN3
forkhead box N3
chrX_+_16964730 0.804 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr3_-_18466759 0.717 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr7_+_94023872 0.692 NM_000089
COL1A2
collagen, type I, alpha 2
chr3_-_18480203 0.662 NM_001131010
SATB1
SATB homeobox 1
chr10_+_92980322 0.635 NM_032373
PCGF5
polycomb group ring finger 5
chr17_+_68165660 0.619 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr11_-_3186556 0.618 NM_001144063
NM_020896
NM_145638
OSBPL5


oxysterol binding protein-like 5


chr9_+_91605777 0.602 NM_001001938
NM_001142413
C9orf47

chromosome 9 open reading frame 47

chr1_+_162466963 0.575 NM_001184763
UHMK1
U2AF homology motif (UHM) kinase 1
chr20_-_30310597 0.564 NM_001191
NM_138578
BCL2L1

BCL2-like 1

chr3_+_141043054 0.557 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr1_-_236228476 0.512 NM_002508
NID1
nidogen 1
chr5_-_58334936 0.505 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr1_+_162467594 0.497 NM_144624
NM_175866
UHMK1

U2AF homology motif (UHM) kinase 1

chr19_+_10543110 0.481 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr6_-_52441815 0.476 NM_012288
TRAM2
translocation associated membrane protein 2
chr1_-_46598250 0.475 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr1_+_78956727 0.456 NM_000959
NM_001039585
PTGFR

prostaglandin F receptor (FP)

chr5_-_59783885 0.440 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_+_129730772 0.436 NM_024900
NM_199320
PHF17

PHD finger protein 17

chr10_-_21463019 0.433 NM_001173484
NM_213569
NEBL

nebulette

chr2_-_227663454 0.422 NM_005544
IRS1
insulin receptor substrate 1
chr19_+_10541334 0.415 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr5_-_146833150 0.414 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr19_+_10563581 0.413 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chr7_-_139477437 0.411 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr5_-_146889618 0.405 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr12_-_108714438 0.402 NM_001142345
CMKLR1
chemokine-like receptor 1
chr16_+_66878281 0.400 NM_005182
CA7
carbonic anhydrase VII
chr12_-_56236614 0.398 NM_002429
MMP19
matrix metallopeptidase 19
chr19_+_10531128 0.397 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr7_+_66093854 0.390 NM_001167961
NM_153033
KCTD7

potassium channel tetramerisation domain containing 7

chr1_-_182361311 0.390 NM_001033044
NM_002065
GLUL

glutamate-ammonia ligase

chr9_-_110252045 0.388 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr16_+_66878840 0.376 NM_001014435
CA7
carbonic anhydrase VII
chr12_-_108733075 0.374 NM_001142343
NM_001142344
NM_004072
CMKLR1


chemokine-like receptor 1


chr19_+_54415990 0.372 NM_031896
CACNG7
calcium channel, voltage-dependent, gamma subunit 7
chr11_-_35547144 0.369 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr2_+_7057471 0.364 NM_014746
RNF144A
ring finger protein 144A
chr3_-_88199015 0.363 NM_001195308
CGGBP1
CGG triplet repeat binding protein 1
chr9_+_79056581 0.358 NM_001097634
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr5_+_156693051 0.352 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr1_-_182360400 0.350 NM_001033056
GLUL
glutamate-ammonia ligase
chr13_+_102104941 0.350 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr3_+_29322802 0.349 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr8_+_26371461 0.346 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr9_+_79115548 0.329 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr5_-_59189620 0.328 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_+_204192915 0.321 NM_005759
ABI2
abl-interactor 2
chr9_+_79074067 0.319 NM_001097633
NM_001490
GCNT1

glucosaminyl (N-acetyl) transferase 1, core 2

chr20_+_5986560 0.318 NM_019095
CRLS1
cardiolipin synthase 1
chr7_-_47621741 0.317 NM_022748
TNS3
tensin 3
chr9_+_79093256 0.316 NM_001097635
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr10_-_21186530 0.315 NM_006393
NEBL
nebulette
chr19_-_17414083 0.311 NM_024527
ABHD8
abhydrolase domain containing 8
chr6_+_84743250 0.311 NM_138409
MRAP2
melanocortin 2 receptor accessory protein 2
chr2_+_241938254 0.309 NM_001080437
SNED1
sushi, nidogen and EGF-like domains 1
chr12_-_63328663 0.308 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr5_+_156696351 0.308 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr2_-_27294491 0.308 NM_001134693
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr10_-_98945662 0.306 NM_003061
SLIT1
slit homolog 1 (Drosophila)
chr5_-_58295758 0.305 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_+_154238196 0.304 NM_004779
CNOT8
CCR4-NOT transcription complex, subunit 8
chr5_+_161277391 0.300 NM_001127647
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr2_-_188419185 0.293 NM_001032281
NM_006287
TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr20_+_33292117 0.293 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chrX_+_108780235 0.289 NM_001242618
NXT2
nuclear transport factor 2-like export factor 2
chr5_+_161274939 0.284 NM_001127644
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr20_-_34025955 0.282 NM_000557
GDF5
growth differentiation factor 5
chr8_+_26435339 0.279 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr19_+_4910339 0.276 NM_013282
UHRF1
ubiquitin-like with PHD and ring finger domains 1
chr1_-_163172624 0.274 NM_001195303
RGS5
regulator of G-protein signaling 5
chr5_+_161277702 0.274 NM_001127648
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_161275541 0.274 NM_001127645
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr2_-_214016332 0.273 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr5_+_71403040 0.272 NM_005909
MAP1B
microtubule-associated protein 1B
chr13_-_110438896 0.271 NM_003749
IRS2
insulin receptor substrate 2
chr7_-_6312137 0.267 NM_004227
CYTH3
cytohesin 3
chr5_-_58652671 0.266 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_163172863 0.266 NM_003617
RGS5
regulator of G-protein signaling 5
chr1_+_183605207 0.265 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr5_+_161275897 0.265 NM_001127646
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_-_95392501 0.263 NM_001839
CNN3
calponin 3, acidic
chr11_-_62494785 0.262 NM_001079559
HNRNPUL2-BSCL2
HNRNPUL2
HNRNPUL2-BSCL2 readthrough
heterogeneous nuclear ribonucleoprotein U-like 2
chr19_+_50879681 0.261 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr5_-_59064437 0.261 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_242212244 0.258 NM_001243900
NM_203346
HDLBP

high density lipoprotein binding protein

chr5_-_58571916 0.258 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_114682836 0.255 NM_001221
NM_172114
NM_172115
NM_172127
NM_172128
NM_172129
CAMK2D





calcium/calmodulin-dependent protein kinase II delta





chr12_-_29936685 0.254 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr21_+_47518012 0.254 NM_001849
NM_058174
NM_058175
COL6A2


collagen, type VI, alpha 2


chr5_+_161274684 0.253 NM_001127643
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr19_+_4909447 0.252 NM_001048201
UHRF1
ubiquitin-like with PHD and ring finger domains 1
chr12_-_29937691 0.247 NM_175861
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chrX_+_108779009 0.246 NM_018698
NXT2
nuclear transport factor 2-like export factor 2
chr5_+_31532372 0.245 NM_018356
C5orf22
chromosome 5 open reading frame 22
chr7_+_149570004 0.240 NM_001100592
NM_145230
ATP6V0E2

ATPase, H+ transporting V0 subunit e2

chr1_-_54199876 0.237 NM_147193
GLIS1
GLIS family zinc finger 1
chr22_+_42086546 0.236 NM_001142964
C22orf46
chromosome 22 open reading frame 46
chr1_+_26146376 0.236 NM_001099625
NM_001099627
FAM54B

family with sequence similarity 54, member B

chr3_-_12705626 0.235 NM_002880
RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chr1_+_26146622 0.235 NM_019557
FAM54B
family with sequence similarity 54, member B
chr17_-_19290471 0.234 NM_001198695
NM_002404
MFAP4

microfibrillar-associated protein 4

chr14_+_58765209 0.231 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr17_-_42908178 0.231 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr21_+_48055506 0.228 NM_001242864
NM_001242865
NM_001242866
NM_001535
NM_206962
PRMT2




protein arginine methyltransferase 2




chr1_+_26147318 0.227 NM_001099626
FAM54B
family with sequence similarity 54, member B
chr9_-_72374855 0.226 NM_001099666
PTAR1
protein prenyltransferase alpha subunit repeat containing 1
chr7_+_117824085 0.224 NM_016200
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr6_+_30524485 0.223 NM_001077497
NM_025263
PRR3

proline rich 3

chr8_+_37654395 0.222 NM_032777
GPR124
G protein-coupled receptor 124
chr12_+_1726221 0.220 NM_030775
WNT5B
wingless-type MMTV integration site family, member 5B
chr2_-_242255114 0.217 NM_005336
HDLBP
high density lipoprotein binding protein
chr17_-_4167028 0.216 NM_016376
NM_020740
ANKFY1

ankyrin repeat and FYVE domain containing 1

chr12_+_1738411 0.216 NM_032642
WNT5B
wingless-type MMTV integration site family, member 5B
chr20_+_45338125 0.212 NM_030777
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chr1_+_61547625 0.212 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr6_+_11538486 0.212 NM_001100829
TMEM170B
transmembrane protein 170B
chr19_+_44037287 0.210 NM_174945
ZNF575
zinc finger protein 575
chrX_+_30671456 0.209 NM_000167
NM_001128127
NM_001205019
NM_203391
GK



glycerol kinase



chrX_+_108780058 0.207 NM_001242617
NXT2
nuclear transport factor 2-like export factor 2
chr2_-_179343225 0.206 NM_001135212
NM_181342
FKBP7

FK506 binding protein 7

chr5_-_180688095 0.204 NM_032765
TRIM52
tripartite motif containing 52
chr20_+_5987897 0.204 NM_001127458
CRLS1
cardiolipin synthase 1
chr3_+_148447966 0.204 NM_032049
AGTR1
angiotensin II receptor, type 1
chr2_+_201170603 0.204 NM_015535
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr18_+_9137560 0.202 NM_001204056
ANKRD12
ankyrin repeat domain 12
chr17_-_33700619 0.201 NM_001104587
NM_001104588
NM_001104589
NM_001104590
NM_152270
SLFN11




schlafen family member 11




chr3_+_12392993 0.194 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr15_+_44084039 0.193 NM_001018108
NM_001199875
NM_001199876
SERF2


small EDRK-rich factor 2


chr3_+_12330336 0.192 NM_138711
PPARG
peroxisome proliferator-activated receptor gamma
chr3_+_148415657 0.192 NM_000685
NM_004835
NM_009585
NM_031850
AGTR1



angiotensin II receptor, type 1



chr13_+_115079943 0.192 NM_001164144
NM_001164145
NM_032436
CHAMP1


chromosome alignment maintaining phosphoprotein 1


chr13_-_74707913 0.191 NM_007249
KLF12
Kruppel-like factor 12
chr12_+_1929432 0.190 NM_001039029
NM_001163925
NM_001163926
LRTM2


leucine-rich repeats and transmembrane domains 2


chr15_-_78369825 0.190 NM_015079
NM_144572
TBC1D2B

TBC1 domain family, member 2B

chr5_-_38556682 0.189 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr3_-_149688638 0.189 NM_002628
NM_053024
PFN2

profilin 2

chr18_+_9136742 0.185 NM_001083625
NM_015208
ANKRD12

ankyrin repeat domain 12

chr5_-_38595506 0.185 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr1_+_164528586 0.184 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr2_+_178257371 0.183 NM_003659
AGPS
alkylglycerone phosphate synthase
chr3_+_12329332 0.183 NM_005037
NM_138712
PPARG

peroxisome proliferator-activated receptor gamma

chr1_-_150780705 0.182 NM_000396
CTSK
cathepsin K
chr15_+_44069272 0.182 NM_001199877
SERF2
small EDRK-rich factor 2
chr5_+_304290 0.179 NM_001242412
NM_020731
AHRR

aryl-hydrocarbon receptor repressor

chr15_+_91643429 0.179 NM_014848
SV2B
synaptic vesicle glycoprotein 2B
chr10_+_86088156 0.178 NM_018999
FAM190B
family with sequence similarity 190, member B
chr2_+_201997687 0.178 NM_001202518
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_+_61542928 0.177 NM_001145511
NFIA
nuclear factor I/A
chr2_+_201170795 0.177 NM_001100422
NM_001100424
NM_001100423
SPATS2L


spermatogenesis associated, serine-rich 2-like


chr12_-_6665220 0.176 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chr11_-_33744272 0.174 NM_001127223
NM_001127225
NM_001127226
CD59


CD59 molecule, complement regulatory protein


chr2_-_214015053 0.174 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr2_+_30454396 0.173 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr18_-_57364643 0.172 NM_133459
CCBE1
collagen and calcium binding EGF domains 1
chr1_+_202509241 0.171 NM_001197131
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr5_+_137673223 0.171 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr11_+_58346575 0.170 NM_001197051
NM_053023
ZFP91

zinc finger protein 91 homolog (mouse)

chr20_+_30945988 0.168 NM_001164603
NM_015338
ASXL1

additional sex combs like 1 (Drosophila)

chr2_-_190044330 0.166 NM_000393
COL5A2
collagen, type V, alpha 2
chr1_+_202431870 0.166 NM_032103
NM_032104
PPP1R12B

protein phosphatase 1, regulatory subunit 12B

chr7_-_92777657 0.165 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr17_-_33390676 0.165 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr17_-_42907606 0.165 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr15_-_45815001 0.165 NM_013309
SLC30A4
solute carrier family 30 (zinc transporter), member 4
chr15_+_57210823 0.165 NM_003205
NM_207036
NM_207037
NM_207038
TCF12



transcription factor 12



chr18_-_70534809 0.164 NM_001201465
NM_138966
NETO1

neuropilin (NRP) and tolloid (TLL)-like 1

chr9_-_123476578 0.163 NM_001080497
MEGF9
multiple EGF-like-domains 9
chrX_-_150067127 0.162 NM_001184808
NM_001242614
NM_031462
NM_134445
NM_134446
CD99L2




CD99 molecule-like 2




chr7_+_43966007 0.161 NM_015983
UBE2D4
ubiquitin-conjugating enzyme E2D 4 (putative)
chr11_-_33744497 0.159 NM_001127227
CD59
CD59 molecule, complement regulatory protein
chr8_+_17354562 0.157 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr7_+_8008416 0.154 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr5_+_137673702 0.151 NM_016605
FAM53C
family with sequence similarity 53, member C
chr8_+_27183062 0.146 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr5_-_14871555 0.145 NM_054027
ANKH
ankylosis, progressive homolog (mouse)
chr5_+_158690088 0.145 NM_145049
UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr3_-_112359962 0.144 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr7_-_42276617 0.144 NM_000168
GLI3
GLI family zinc finger 3
chr10_-_81205091 0.144 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr11_+_67776016 0.143 NM_001161473
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr8_+_27182995 0.143 NM_173176
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr2_+_233498206 0.142 NM_025202
EFHD1
EF-hand domain family, member D1
chr5_+_131630065 0.142 NM_003059
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.71 2.07e-05 GO:0016567 protein ubiquitination
2.52 1.59e-04 GO:0032446 protein modification by small protein conjugation
1.50 2.07e-04 GO:0043412 macromolecule modification
1.50 7.24e-04 GO:0006464 protein modification process
2.22 2.57e-03 GO:0070647 protein modification by small protein conjugation or removal
1.66 2.52e-02 GO:0051128 regulation of cellular component organization

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.80 6.80e-06 GO:0004842 ubiquitin-protein ligase activity
2.64 3.29e-05 GO:0019787 small conjugating protein ligase activity
2.38 9.10e-05 GO:0016879 ligase activity, forming carbon-nitrogen bonds
2.46 1.09e-04 GO:0016881 acid-amino acid ligase activity
1.17 3.45e-03 GO:0005515 protein binding
1.87 9.42e-03 GO:0016874 ligase activity
1.25 1.33e-02 GO:0043167 ion binding
1.09 1.36e-02 GO:0005488 binding
1.24 2.07e-02 GO:0043169 cation binding
1.24 2.27e-02 GO:0046872 metal ion binding