Motif ID: GTF2I.p2

Z-value: 2.038


Transcription factors associated with GTF2I.p2:

Gene SymbolEntrez IDGene Name
GTF2I 2969 general transcription factor II, i

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GTF2Ichr7_+_740720380.667.8e-02Click!


Activity profile for motif GTF2I.p2.

activity profile for motif GTF2I.p2


Sorted Z-values histogram for motif GTF2I.p2

Sorted Z-values for motif GTF2I.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2I.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_152760452 2.302 BGN
biglycan
chrX_+_152760346 2.301 NM_001711
BGN
biglycan
chr2_+_128175989 1.562 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr2_+_128176019 1.555 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr5_-_81046858 1.464 SSBP2
single-stranded DNA binding protein 2
chr8_+_97506141 1.359 SDC2
syndecan 2
chr8_-_93115453 1.332 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr19_-_2015628 1.326 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr5_-_81046943 1.311 NM_012446
SSBP2
single-stranded DNA binding protein 2
chr5_+_139028025 1.281 NM_016463
CXXC5
CXXC finger protein 5
chr19_-_49149252 1.220 NM_001217
CA11
carbonic anhydrase XI
chr2_+_148778573 1.216 NM_018328
MBD5
methyl-CpG binding domain protein 5
chr7_+_94024201 1.192 COL1A2
collagen, type I, alpha 2
chr7_-_150973819 1.154 NM_001003802
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr13_+_88324777 1.154 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr8_+_97505895 1.136 SDC2
syndecan 2
chr12_+_94542239 1.114 NM_005761
PLXNC1
plexin C1
chr5_-_149535309 1.089 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr6_+_72596699 1.081 RIMS1
regulating synaptic membrane exocytosis 1
chr14_-_61115906 1.050 NM_005982
SIX1
SIX homeobox 1
chr5_+_92920592 1.014 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr8_+_97506071 1.009 SDC2
syndecan 2
chr8_+_97506020 1.003 SDC2
syndecan 2
chr1_-_72748147 0.969 NM_173808
NEGR1
neuronal growth regulator 1
chr5_-_149535138 0.956 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr6_-_46459010 0.946 NM_001251974
RCAN2
regulator of calcineurin 2
chr10_+_31608097 0.932 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr7_-_150974179 0.873 NM_003078
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr10_-_21463019 0.858 NM_001173484
NM_213569
NEBL

nebulette

chr8_+_97505876 0.843 NM_002998
SDC2
syndecan 2
chr5_-_111093030 0.837 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr1_+_159141376 0.824 NM_021189
NM_001127173
CADM3

cell adhesion molecule 3

chr12_+_56075329 0.818 NM_152637
METTL7B
methyltransferase like 7B
chr1_-_72748491 0.817


chr14_+_24837225 0.813 NM_001198965
NM_004554
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr10_+_111969988 0.806 NM_001008541
MXI1
MAX interactor 1
chr14_-_89883306 0.805 NM_005197
FOXN3
forkhead box N3
chr1_+_183605207 0.797 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr19_+_46367517 0.795 NM_004497
FOXA3
forkhead box A3
chr5_+_139027955 0.793 CXXC5
CXXC finger protein 5
chr11_-_2160199 0.767 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr5_+_139027868 0.748 CXXC5
CXXC finger protein 5
chr8_-_93107881 0.719 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr11_-_3186556 0.708 NM_001144063
NM_020896
NM_145638
OSBPL5


oxysterol binding protein-like 5


chr5_-_111092918 0.700 NM_004772
C5orf13
chromosome 5 open reading frame 13
chrX_+_54834775 0.690 NM_014599
MAGED2
melanoma antigen family D, 2
chr10_+_20105344 0.684 NM_032812
PLXDC2
plexin domain containing 2
chr9_+_133320093 0.681 NM_000050
NM_054012
ASS1

argininosuccinate synthase 1

chr8_-_93107442 0.679 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr5_-_149535420 0.676 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr5_+_139028483 0.676 CXXC5
CXXC finger protein 5
chr5_+_139027907 0.676 CXXC5
CXXC finger protein 5
chr11_+_130318457 0.668 NM_139055
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr15_-_82338459 0.660 MEX3B
mex-3 homolog B (C. elegans)
chr19_-_14201230 0.657 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr2_-_45236521 0.654 NM_016932
SIX2
SIX homeobox 2
chr10_+_111985628 0.654 NM_005962
MXI1
MAX interactor 1
chr7_+_94023872 0.649 NM_000089
COL1A2
collagen, type I, alpha 2
chr1_+_164528586 0.648 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr3_-_157823815 0.646 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr3_+_42700837 0.644 ZBTB47
zinc finger and BTB domain containing 47
chr10_-_21462987 0.642 NEBL
nebulette
chr15_-_82338348 0.636 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr5_-_111092865 0.631 C5orf13
chromosome 5 open reading frame 13
chr15_-_27018160 0.630 GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr2_+_200323088 0.625


chr2_-_145277568 0.622 ZEB2
zinc finger E-box binding homeobox 2
chr5_+_92918924 0.621 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr11_+_113930430 0.611 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr8_-_38325524 0.611 FGFR1
fibroblast growth factor receptor 1
chr1_+_164528914 0.602 PBX1
pre-B-cell leukemia homeobox 1
chr1_-_92351476 0.601 TGFBR3
transforming growth factor, beta receptor III
chr11_-_3186507 0.598 OSBPL5
oxysterol binding protein-like 5
chr8_+_37654833 0.593 GPR124
G protein-coupled receptor 124
chr8_+_37654757 0.582 GPR124
G protein-coupled receptor 124
chr10_+_12391708 0.582 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr19_-_54984341 0.578 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr20_-_48099178 0.576 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr7_-_28220146 0.565 JAZF1
JAZF zinc finger 1
chr22_+_45898690 0.564 NM_001996
NM_006485
NM_006486
NM_006487
FBLN1



fibulin 1



chr11_-_130184314 0.553 ZBTB44
zinc finger and BTB domain containing 44
chr3_-_18466759 0.549 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr8_-_141467853 0.544 NM_001160372
TRAPPC9
trafficking protein particle complex 9
chr13_-_67804432 0.544 NM_020403
NM_203487
PCDH9

protocadherin 9

chr7_+_8008416 0.544 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr4_-_138453628 0.538 NM_019035
PCDH18
protocadherin 18
chr6_+_72596405 0.536 RIMS1
regulating synaptic membrane exocytosis 1
chr19_+_54369610 0.535 NM_001020820
MYADM
myeloid-associated differentiation marker
chr4_+_145567147 0.535 NM_022475
HHIP
hedgehog interacting protein
chr11_-_2159472 0.531 IGF2
insulin-like growth factor 2 (somatomedin A)
chr20_+_36531548 0.526 VSTM2L
V-set and transmembrane domain containing 2 like
chr12_+_57853917 0.516 NM_001160045
NM_001167609
NM_005269
GLI1


GLI family zinc finger 1


chr7_+_73442451 0.514 ELN
elastin
chr19_-_41933255 0.512


chr20_+_36531498 0.512 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chr15_-_27018108 0.512 GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr11_-_3186522 0.510 OSBPL5
oxysterol binding protein-like 5
chr12_-_53893195 0.503 NM_001193511
NM_006301
MAP3K12

mitogen-activated protein kinase kinase kinase 12

chr6_+_89790412 0.502 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr8_-_141467810 0.500 TRAPPC9
trafficking protein particle complex 9
chr4_-_138453564 0.500 PCDH18
protocadherin 18
chr3_+_54156573 0.499 CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr2_+_27301434 0.489 NM_007046
EMILIN1
elastin microfibril interfacer 1
chr9_-_98270321 0.488 NM_001083604
NM_001083605
PTCH1

patched 1

chr2_+_23608297 0.483 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr7_+_73442426 0.483 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chr1_-_33168356 0.483 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr13_+_93879011 0.475 NM_005708
GPC6
glypican 6
chr20_+_43374487 0.474 NM_022358
KCNK15
potassium channel, subfamily K, member 15
chr8_-_11058847 0.471 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr16_+_29823557 0.469 PRRT2
proline-rich transmembrane protein 2
chr7_+_73442486 0.469 ELN
elastin
chr8_-_93107643 0.467 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_72596648 0.467 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chrX_-_151143096 0.466 NM_004961
GABRE
gamma-aminobutyric acid (GABA) A receptor, epsilon
chr16_+_85645014 0.461 NM_001134473
KIAA0182
KIAA0182
chr6_+_89790464 0.459 PNRC1
proline-rich nuclear receptor coactivator 1
chr7_+_142552547 0.459 NM_004445
EPHB6
EPH receptor B6
chr6_+_101846860 0.455 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr1_+_155829259 0.454 NM_152280
SYT11
synaptotagmin XI
chr3_-_151987332 0.453 LOC401093
uncharacterized LOC401093
chr10_+_12391471 0.452 NM_020397
NM_153498
CAMK1D

calcium/calmodulin-dependent protein kinase ID

chr5_+_71403040 0.448 NM_005909
MAP1B
microtubule-associated protein 1B
chrX_-_112084006 0.444 NM_133265
AMOT
angiomotin
chr1_-_167906277 0.443 NM_001143674
NM_015415
BRP44

brain protein 44

chr11_-_65640199 0.441 NM_016938
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr6_-_88875766 0.441 NM_001160226
NM_001160258
NM_001160259
NM_016083
CNR1



cannabinoid receptor 1 (brain)



chr20_-_31071384 0.441 C20orf112
chromosome 20 open reading frame 112
chr2_+_219264477 0.438 NM_021198
NM_182642
CTDSP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1

chrX_-_107019001 0.436 NM_198057
TSC22D3
TSC22 domain family, member 3
chr2_+_27301693 0.432 EMILIN1
elastin microfibril interfacer 1
chr7_+_100199881 0.431 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr16_+_69599869 0.431 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr13_+_58205943 0.429 PCDH17
protocadherin 17
chr6_-_46459710 0.427 NM_001251973
RCAN2
regulator of calcineurin 2
chr16_-_30107492 0.422 NM_031477
NM_001145524
YPEL3

yippee-like 3 (Drosophila)

chr2_-_200322699 0.421 NM_001172509
SATB2
SATB homeobox 2
chr11_-_70672644 0.418 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr5_-_171710794 0.416 NM_152277
UBTD2
ubiquitin domain containing 2
chr14_+_24838301 0.414 NM_001198966
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr15_-_27018216 0.414 NM_000814
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr1_+_226250413 0.412 H3F3A
H3 histone, family 3A
chr17_-_36904545 0.409 NM_007144
PCGF2
polycomb group ring finger 2
chr14_+_21538339 0.408 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr15_-_80216004 0.408 ST20
suppressor of tumorigenicity 20
chr16_+_29823408 0.407 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr6_+_108882104 0.406 FOXO3
forkhead box O3
chr8_-_22549901 0.405 NM_001199880
EGR3
early growth response 3
chr17_-_53800074 0.404 NM_018286
TMEM100
transmembrane protein 100
chr12_-_56106061 0.402 NM_001144997
ITGA7
integrin, alpha 7
chr14_+_24836144 0.401 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr4_-_5890142 0.400 CRMP1
collapsin response mediator protein 1
chr2_+_219264719 0.397 CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr1_+_211432693 0.396 NM_001136223
NM_001136224
NM_001136225
RCOR3


REST corepressor 3


chr8_-_38325241 0.395 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chr8_+_104512975 0.395 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr16_-_65155881 0.395 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chrX_+_103031753 0.395 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr6_-_31514620 0.392 NM_001204078
NM_130463
NM_138282
ATP6V1G2


ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2


chr3_+_20081853 0.388 KAT2B
K(lysine) acetyltransferase 2B
chr11_+_1886394 0.387 NM_001242932
LSP1
lymphocyte-specific protein 1
chrX_-_48828250 0.386 NM_004979
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr1_-_92351613 0.385 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr6_+_108881010 0.384 NM_201559
FOXO3
forkhead box O3
chr11_-_3186475 0.383 OSBPL5
oxysterol binding protein-like 5
chr11_+_12399024 0.381 NM_018222
PARVA
parvin, alpha
chr12_+_53442732 0.378 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr2_-_145277879 0.378 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr5_-_150537335 0.373 NM_001155
ANXA6
annexin A6
chr6_-_31697568 0.372 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_+_50016435 0.371 NM_004107
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_-_1771823 0.370 NM_001170820
IFITM10
interferon induced transmembrane protein 10
chr5_+_169532900 0.368 NM_012188
NM_144769
FOXI1

forkhead box I1

chr9_+_127539382 0.361 NM_182487
OLFML2A
olfactomedin-like 2A
chr5_+_149569810 0.361 SLC6A7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr17_-_43045612 0.361 NM_006688
C1QL1
complement component 1, q subcomponent-like 1
chr11_+_47279467 0.360 NM_001130101
NM_005693
NR1H3

nuclear receptor subfamily 1, group H, member 3

chr13_-_114018201 0.359 GRTP1
growth hormone regulated TBC protein 1
chr20_+_12989616 0.352 NM_018327
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr5_+_172261220 0.352 NM_001031711
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr5_+_172483285 0.351 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr12_+_53846086 0.350 PCBP2
poly(rC) binding protein 2
chr20_+_13976014 0.349 NM_080676
MACROD2
MACRO domain containing 2
chr9_-_16870664 0.349 BNC2
basonuclin 2
chr5_-_111093251 0.349 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr3_+_20081523 0.348 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr19_+_35521591 0.345 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr3_+_54156691 0.344 NM_018398
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr9_-_89562103 0.344 NM_002048
GAS1
growth arrest-specific 1
chr18_-_500583 0.343 NM_130386
COLEC12
collectin sub-family member 12
chr6_+_30524662 0.342 PRR3
proline rich 3
chr3_-_114866090 0.342 NM_015642
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_57914287 0.340 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr1_-_150849043 0.339 ARNT
aryl hydrocarbon receptor nuclear translocator
chr14_-_94595925 0.338 NM_032036
IFI27L2
interferon, alpha-inducible protein 27-like 2
chr11_-_2159925 0.338 IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_-_150849211 0.337 NM_001197325
NM_001668
NM_178427
ARNT


aryl hydrocarbon receptor nuclear translocator


chrX_+_66763868 0.334 NM_000044
AR
androgen receptor
chr2_-_25564745 0.333 NM_022552
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr5_-_150537261 0.332 ANXA6
annexin A6

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.19 7.38e-27 GO:0050794 regulation of cellular process
1.17 1.14e-25 GO:0050789 regulation of biological process
1.15 2.90e-22 GO:0065007 biological regulation
1.30 5.04e-16 GO:0048522 positive regulation of cellular process
1.08 5.68e-15 GO:0009987 cellular process
1.27 1.01e-14 GO:0048518 positive regulation of biological process
1.30 5.09e-14 GO:0048523 negative regulation of cellular process
1.28 1.07e-13 GO:0048519 negative regulation of biological process
1.21 9.24e-13 GO:0031323 regulation of cellular metabolic process
1.20 2.73e-12 GO:0019222 regulation of metabolic process
1.24 3.60e-12 GO:0048731 system development
1.21 4.65e-12 GO:0080090 regulation of primary metabolic process
1.22 8.66e-12 GO:0048856 anatomical structure development
1.34 3.68e-11 GO:0007399 nervous system development
1.20 6.88e-11 GO:0007275 multicellular organismal development
1.21 9.37e-11 GO:0060255 regulation of macromolecule metabolic process
1.19 1.35e-10 GO:0032502 developmental process
1.32 2.59e-10 GO:0009653 anatomical structure morphogenesis
1.19 5.21e-09 GO:0016043 cellular component organization
1.16 1.14e-08 GO:0044260 cellular macromolecule metabolic process
1.18 1.16e-08 GO:0023052 signaling
1.39 1.53e-08 GO:0022008 neurogenesis
1.22 1.59e-08 GO:0010468 regulation of gene expression
1.22 2.73e-08 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.37 3.30e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.22 3.62e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.16 3.88e-08 GO:0051716 cellular response to stimulus
1.21 4.64e-08 GO:0031326 regulation of cellular biosynthetic process
1.21 5.02e-08 GO:0009889 regulation of biosynthetic process
1.28 6.33e-08 GO:0023051 regulation of signaling
1.18 7.45e-08 GO:0071840 cellular component organization or biogenesis
1.38 1.55e-07 GO:0048699 generation of neurons
1.20 1.81e-07 GO:0051171 regulation of nitrogen compound metabolic process
1.20 4.33e-07 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30 5.25e-07 GO:0009893 positive regulation of metabolic process
1.23 7.17e-07 GO:0048869 cellular developmental process
1.11 8.82e-07 GO:0044237 cellular metabolic process
1.13 9.89e-07 GO:0043170 macromolecule metabolic process
1.17 1.12e-06 GO:0007165 signal transduction
1.24 1.21e-06 GO:0048513 organ development
1.31 1.35e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.23 1.54e-06 GO:0030154 cell differentiation
1.41 1.60e-06 GO:0009719 response to endogenous stimulus
1.30 1.76e-06 GO:0031325 positive regulation of cellular metabolic process
1.20 8.83e-06 GO:0051252 regulation of RNA metabolic process
1.35 8.98e-06 GO:0051128 regulation of cellular component organization
1.38 1.33e-05 GO:0030182 neuron differentiation
1.41 1.35e-05 GO:0009725 response to hormone stimulus
1.20 1.53e-05 GO:0006355 regulation of transcription, DNA-dependent
1.19 1.68e-05 GO:0044267 cellular protein metabolic process
1.42 1.86e-05 GO:0048666 neuron development
1.18 1.94e-05 GO:0071842 cellular component organization at cellular level
1.30 2.40e-05 GO:0010646 regulation of cell communication
1.31 2.61e-05 GO:0009892 negative regulation of metabolic process
1.22 2.64e-05 GO:0006464 protein modification process
1.44 3.28e-05 GO:0031175 neuron projection development
1.32 3.59e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.25 4.51e-05 GO:0009966 regulation of signal transduction
1.31 4.88e-05 GO:0032774 RNA biosynthetic process
1.21 5.68e-05 GO:0043412 macromolecule modification
1.29 6.25e-05 GO:0010941 regulation of cell death
1.30 6.31e-05 GO:0032879 regulation of localization
1.45 8.90e-05 GO:0048812 neuron projection morphogenesis
1.31 8.99e-05 GO:0031324 negative regulation of cellular metabolic process
1.29 1.02e-04 GO:0043067 regulation of programmed cell death
1.29 1.23e-04 GO:0042981 regulation of apoptosis
1.31 1.32e-04 GO:0050793 regulation of developmental process
1.38 1.33e-04 GO:0010629 negative regulation of gene expression
1.37 1.52e-04 GO:0030030 cell projection organization
1.21 1.65e-04 GO:0048583 regulation of response to stimulus
1.36 2.05e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.44 2.30e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.52 2.53e-04 GO:0001501 skeletal system development
1.37 2.54e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.33 2.63e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.41 2.65e-04 GO:0000904 cell morphogenesis involved in differentiation
1.41 2.66e-04 GO:0048858 cell projection morphogenesis
1.36 2.98e-04 GO:0032989 cellular component morphogenesis
1.08 3.03e-04 GO:0008152 metabolic process
1.31 3.14e-04 GO:0006351 transcription, DNA-dependent
1.41 3.20e-04 GO:0032990 cell part morphogenesis
1.37 3.68e-04 GO:0009887 organ morphogenesis
1.37 3.69e-04 GO:0000902 cell morphogenesis
1.16 3.77e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.39 3.86e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.33 4.48e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39 4.58e-04 GO:0051253 negative regulation of RNA metabolic process
1.36 5.81e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.09 5.95e-04 GO:0044238 primary metabolic process
1.24 6.14e-04 GO:0051239 regulation of multicellular organismal process
1.40 6.53e-04 GO:0007417 central nervous system development
1.36 8.15e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 8.43e-04 GO:0007409 axonogenesis
1.34 9.22e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.34 9.42e-04 GO:0010628 positive regulation of gene expression
1.33 1.02e-03 GO:0009890 negative regulation of biosynthetic process
1.28 1.14e-03 GO:0048468 cell development
1.26 1.20e-03 GO:0051246 regulation of protein metabolic process
1.48 1.29e-03 GO:0071495 cellular response to endogenous stimulus
1.27 1.57e-03 GO:0032268 regulation of cellular protein metabolic process
1.33 1.70e-03 GO:0045595 regulation of cell differentiation
1.31 2.23e-03 GO:0051049 regulation of transport
1.39 3.14e-03 GO:0072358 cardiovascular system development
1.39 3.14e-03 GO:0072359 circulatory system development
1.40 3.73e-03 GO:0060341 regulation of cellular localization
1.26 3.95e-03 GO:0009605 response to external stimulus
1.14 3.95e-03 GO:0019538 protein metabolic process
1.14 4.02e-03 GO:0034641 cellular nitrogen compound metabolic process
1.22 4.91e-03 GO:0035556 intracellular signal transduction
1.32 5.32e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.15 5.47e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.42 7.15e-03 GO:0043009 chordate embryonic development
1.32 7.93e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.42 8.68e-03 GO:0009792 embryo development ending in birth or egg hatching
1.51 8.72e-03 GO:0030036 actin cytoskeleton organization
1.31 8.80e-03 GO:0051254 positive regulation of RNA metabolic process
1.29 9.29e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.73 9.38e-03 GO:0007050 cell cycle arrest
1.42 1.23e-02 GO:0007420 brain development
1.27 1.79e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.26 1.86e-02 GO:0009891 positive regulation of biosynthetic process
1.16 1.99e-02 GO:0090304 nucleic acid metabolic process
1.44 2.31e-02 GO:0032870 cellular response to hormone stimulus
1.26 2.89e-02 GO:0040011 locomotion
1.27 2.92e-02 GO:2000026 regulation of multicellular organismal development
1.41 2.97e-02 GO:0043434 response to peptide hormone stimulus
1.40 3.04e-02 GO:0016568 chromatin modification
1.29 3.08e-02 GO:0009790 embryo development
1.27 3.23e-02 GO:0016192 vesicle-mediated transport
1.18 3.47e-02 GO:0006996 organelle organization
1.41 3.53e-02 GO:0007411 axon guidance
1.38 3.59e-02 GO:0007264 small GTPase mediated signal transduction
1.12 3.87e-02 GO:0006807 nitrogen compound metabolic process
1.19 4.16e-02 GO:0065009 regulation of molecular function
1.20 4.16e-02 GO:0010033 response to organic substance
1.48 4.46e-02 GO:0007507 heart development
1.44 4.69e-02 GO:0030029 actin filament-based process
1.47 4.75e-02 GO:0000165 MAPKKK cascade
1.43 4.82e-02 GO:0051130 positive regulation of cellular component organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 2.30e-16 GO:0005622 intracellular
1.08 5.54e-15 GO:0044424 intracellular part
1.10 5.60e-12 GO:0005737 cytoplasm
1.12 2.00e-08 GO:0005634 nucleus
1.21 1.66e-06 GO:0005829 cytosol
1.06 6.70e-05 GO:0043226 organelle
1.06 7.38e-05 GO:0043229 intracellular organelle
1.44 8.16e-05 GO:0043005 neuron projection
1.06 2.49e-04 GO:0043227 membrane-bounded organelle
1.06 2.70e-04 GO:0043231 intracellular membrane-bounded organelle
1.37 3.01e-03 GO:0045202 synapse
1.20 3.32e-03 GO:0005654 nucleoplasm
1.42 8.44e-03 GO:0015629 actin cytoskeleton
1.23 1.24e-02 GO:0042995 cell projection
1.55 2.65e-02 GO:0005912 adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 7.51e-27 GO:0005515 protein binding
1.09 3.86e-22 GO:0005488 binding
1.40 1.75e-11 GO:0001071 nucleic acid binding transcription factor activity
1.40 1.75e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
1.34 7.74e-08 GO:0030528 transcription regulator activity
1.38 2.06e-06 GO:0043565 sequence-specific DNA binding
1.43 6.53e-05 GO:0019904 protein domain specific binding
1.17 1.54e-04 GO:0003677 DNA binding
1.18 2.26e-04 GO:0008270 zinc ion binding
1.72 2.73e-04 GO:0003714 transcription corepressor activity
1.47 3.51e-04 GO:0003779 actin binding
1.36 4.44e-04 GO:0008092 cytoskeletal protein binding
1.61 6.86e-04 GO:0003682 chromatin binding
1.32 1.05e-03 GO:0046983 protein dimerization activity
1.13 1.99e-03 GO:0003676 nucleic acid binding
1.11 2.08e-03 GO:0046872 metal ion binding
2.96 2.33e-03 GO:0008601 protein phosphatase type 2A regulator activity
1.40 2.34e-03 GO:0000988 protein binding transcription factor activity
1.40 2.34e-03 GO:0000989 transcription factor binding transcription factor activity
1.40 3.33e-03 GO:0003712 transcription cofactor activity
1.11 3.49e-03 GO:0043167 ion binding
1.11 3.75e-03 GO:0043169 cation binding
2.20 6.78e-03 GO:0019888 protein phosphatase regulator activity
2.10 7.09e-03 GO:0019208 phosphatase regulator activity
1.43 8.84e-03 GO:0008134 transcription factor binding
1.27 9.25e-03 GO:0019899 enzyme binding
1.25 2.36e-02 GO:0042802 identical protein binding
1.14 2.57e-02 GO:0046914 transition metal ion binding