Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 1.069


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HBP1chr7_+_1068094050.695.9e-02Click!
UBTFchr17_-_42296923,
chr17_-_42298881
0.581.3e-01Click!
SSRP1chr11_-_57103324-0.462.5e-01Click!
HMGB3chrX_+_150151757-0.167.1e-01Click!
HMGB2chr4_-_1742554540.049.3e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_92413738 4.342 FBLN5
fibulin 5
chr14_-_92414004 3.099 NM_006329
FBLN5
fibulin 5
chr8_-_108510094 2.717 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr1_+_163038564 2.271 NM_005613
RGS4
regulator of G-protein signaling 4
chr12_-_91573264 2.062 NM_133503
DCN
decorin
chr10_+_70847817 1.941 NM_002727
SRGN
serglycin
chr12_-_91576579 1.847 DCN
decorin
chr2_+_33359607 1.832 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr5_-_111091947 1.807 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chrX_+_86772714 1.763 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr4_-_138453628 1.750 NM_019035
PCDH18
protocadherin 18
chr10_+_70847857 1.702 SRGN
serglycin
chr18_+_3594056 1.684 FLJ35776
uncharacterized LOC649446
chr2_+_189839132 1.613 COL3A1
collagen, type III, alpha 1
chr3_-_114790221 1.345 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr14_-_89883306 1.306 NM_005197
FOXN3
forkhead box N3
chr3_-_112359547 1.255 CCDC80
coiled-coil domain containing 80
chr5_+_95066628 1.157 NM_014899
RHOBTB3
Rho-related BTB domain containing 3
chrX_+_100333835 1.155 NM_021637
TMEM35
transmembrane protein 35
chr3_-_112359443 1.128 CCDC80
coiled-coil domain containing 80
chr6_+_89790412 1.112 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr8_+_70405080 1.109 SULF1
sulfatase 1
chr16_-_4896197 1.099 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr6_+_89790464 1.099 PNRC1
proline-rich nuclear receptor coactivator 1
chr1_-_57045129 1.093 PPAP2B
phosphatidic acid phosphatase type 2B
chr8_+_70405027 1.073 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr1_+_155853546 1.068 SYT11
synaptotagmin XI
chr3_-_112359565 1.068 CCDC80
coiled-coil domain containing 80
chr1_-_31345361 1.065 SDC3
syndecan 3
chr5_-_147286064 1.057 NM_206966
C5orf46
chromosome 5 open reading frame 46
chr14_-_60097531 1.020 NM_206852
RTN1
reticulon 1
chr11_+_113931228 1.010 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr1_-_57045214 0.982 PPAP2B
phosphatidic acid phosphatase type 2B
chr7_+_142560512 0.969 EPHB6
EPH receptor B6
chr1_-_57045235 0.969 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr2_-_200325200 0.947 SATB2
SATB homeobox 2
chrX_-_142723921 0.945 NM_001184749
SLITRK4
SLIT and NTRK-like family, member 4
chr4_-_2263808 0.929 MXD4
MAX dimerization protein 4
chr16_+_86612114 0.928 NM_005250
FOXL1
forkhead box L1
chr10_+_63661012 0.906 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr1_+_159141376 0.897 NM_021189
NM_001127173
CADM3

cell adhesion molecule 3

chr4_-_2263706 0.891 NM_006454
MXD4
MAX dimerization protein 4
chr3_-_187454247 0.883 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr5_+_110407389 0.875 NM_033035
TSLP
thymic stromal lymphopoietin
chr9_-_95298251 0.869 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr9_+_18474078 0.863 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr5_-_111092918 0.861 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr1_+_163038934 0.850 NM_001113381
RGS4
regulator of G-protein signaling 4
chr7_+_93551015 0.847 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr1_-_57044980 0.836 PPAP2B
phosphatidic acid phosphatase type 2B
chrX_+_85517970 0.828 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chr13_-_33780142 0.826 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr17_-_67138013 0.816 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr18_+_72922725 0.815 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr3_-_151987332 0.810 LOC401093
uncharacterized LOC401093
chr14_+_21156922 0.804 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr6_+_155538096 0.797 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr2_+_169923531 0.794 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr17_-_66951381 0.793 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr1_-_232651227 0.792 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr4_+_124317884 0.791 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr1_+_221052735 0.779 NM_021958
HLX
H2.0-like homeobox
chr9_-_95186559 0.775 NM_005014
OMD
osteomodulin
chrX_+_80457302 0.775 NM_003022
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr5_+_15500288 0.770 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr5_-_121413967 0.764 LOX
lysyl oxidase
chr4_-_138453564 0.764 PCDH18
protocadherin 18
chr3_-_114478117 0.763 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr5_-_121413906 0.757 LOX
lysyl oxidase
chr5_-_111312522 0.755 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr6_+_114178516 0.751 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr5_-_168271852 0.745


chr2_-_163099877 0.731 NM_004460
FAP
fibroblast activation protein, alpha
chr5_+_156820161 0.729 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr6_+_136172802 0.716 NM_018945
PDE7B
phosphodiesterase 7B
chr4_+_70916158 0.705 NM_002159
HTN1
histatin 1
chr12_+_53443834 0.689 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr7_-_47621635 0.686 TNS3
tensin 3
chr13_-_67804432 0.679 NM_020403
NM_203487
PCDH9

protocadherin 9

chr6_-_46293404 0.678 RCAN2
regulator of calcineurin 2
chrX_+_22050920 0.677 NM_000444
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr13_-_74708361 0.676 KLF12
Kruppel-like factor 12
chr1_-_26233367 0.670 NM_203399
STMN1
stathmin 1
chr5_-_111092865 0.668 C5orf13
chromosome 5 open reading frame 13
chr8_-_38325524 0.666 FGFR1
fibroblast growth factor receptor 1
chr5_-_121414011 0.663 NM_002317
LOX
lysyl oxidase
chr13_+_24144402 0.662 NM_001204459
NM_148957
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr9_-_16727887 0.658 BNC2
basonuclin 2
chr5_+_140571903 0.653 NM_018930
PCDHB10
protocadherin beta 10
chrX_-_62974341 0.648 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr10_-_32667543 0.647 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr3_-_114343052 0.643 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr7_-_47621741 0.643 NM_022748
TNS3
tensin 3
chr6_-_139695784 0.643 NM_006079
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr18_+_7946885 0.641 PTPRM
protein tyrosine phosphatase, receptor type, M
chr6_-_139695739 0.638 CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr14_-_73493744 0.636 NM_021260
ZFYVE1
zinc finger, FYVE domain containing 1
chr10_+_69869249 0.635 NM_032578
MYPN
myopalladin
chr1_+_39875175 0.630 NM_015038
KIAA0754
KIAA0754
chr13_-_33760215 0.627 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr12_-_91576805 0.621 NM_001920
DCN
decorin
chr8_-_38326115 0.620 FGFR1
fibroblast growth factor receptor 1
chr5_-_158526698 0.615 NM_024007
EBF1
early B-cell factor 1
chr6_-_139695349 0.613 NM_001168389
NM_001168388
CITED2

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

chr10_+_31610063 0.613 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr8_-_38325241 0.612 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chrX_+_51927918 0.607 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chr11_+_19372270 0.607 NM_001111018
NAV2
neuron navigator 2
chr2_+_12857885 0.594 TRIB2
tribbles homolog 2 (Drosophila)
chrX_+_135251795 0.593 NM_001167819
FHL1
four and a half LIM domains 1
chr16_+_15528324 0.593 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr7_-_27183225 0.588 NM_019102
HOXA5
homeobox A5
chr6_+_21666645 0.585 LINC00340
long intergenic non-protein coding RNA 340
chr3_-_112359863 0.585 CCDC80
coiled-coil domain containing 80
chr3_-_112358510 0.584 CCDC80
coiled-coil domain containing 80
chr13_+_93879011 0.579 NM_005708
GPC6
glypican 6
chr1_-_85930610 0.579 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr7_+_134464372 0.576 CALD1
caldesmon 1
chr12_-_92539614 0.573 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr8_+_72756335 0.569


chr8_+_72756218 0.562 LOC100132891
uncharacterized LOC100132891
chr2_+_128176019 0.562 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr8_-_60031545 0.558 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr4_+_52917440 0.557 NM_145263
SPATA18
spermatogenesis associated 18 homolog (rat)
chr3_-_112359962 0.555 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr20_-_45985411 0.554 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr11_-_111782447 0.552 NM_001885
CRYAB
crystallin, alpha B
chr6_+_72596699 0.551 RIMS1
regulating synaptic membrane exocytosis 1
chr3_-_112358758 0.548 CCDC80
coiled-coil domain containing 80
chr8_-_124553448 0.548 NM_001242463
NM_058229
FBXO32

F-box protein 32

chr1_+_221052845 0.545 HLX
H2.0-like homeobox
chr20_+_123230 0.541 NM_030931
DEFB126
defensin, beta 126
chr3_-_112359660 0.539 CCDC80
coiled-coil domain containing 80
chr4_+_70894129 0.537 NM_000200
HTN3
histatin 3
chr9_+_118916069 0.535 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chrX_-_51812249 0.535 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chr13_-_74707913 0.535 NM_007249
KLF12
Kruppel-like factor 12
chr5_+_172068188 0.534 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr1_+_51435911 0.532 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr6_+_72596405 0.527 RIMS1
regulating synaptic membrane exocytosis 1
chr3_-_18480203 0.526 NM_001131010
SATB1
SATB homeobox 1
chr2_+_128175989 0.522 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr5_+_138677570 0.516 PAIP2
poly(A) binding protein interacting protein 2
chr5_+_71403040 0.514 NM_005909
MAP1B
microtubule-associated protein 1B
chr17_+_65822206 0.508 BPTF
bromodomain PHD finger transcription factor
chr14_+_77228132 0.505 NM_014909
VASH1
vasohibin 1
chr3_-_112359277 0.504 CCDC80
coiled-coil domain containing 80
chr3_-_112359251 0.503 CCDC80
coiled-coil domain containing 80
chr7_-_27142301 0.502 NM_006735
HOXA2
homeobox A2
chr6_+_124125068 0.498 NM_001040214
NM_153355
NKAIN2

Na+/K+ transporting ATPase interacting 2

chr8_-_93075190 0.497 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_+_135251454 0.494 NM_001159704
FHL1
four and a half LIM domains 1
chr1_-_201476218 0.488 CSRP1
cysteine and glycine-rich protein 1
chr17_-_21156577 0.484 NM_152914
C17orf103
chromosome 17 open reading frame 103
chr1_-_86043932 0.482 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr1_-_27998719 0.481 NM_002038
NM_022872
NM_022873
IFI6


interferon, alpha-inducible protein 6


chr2_-_225266710 0.480 NM_001122779
NM_024785
FAM124B

family with sequence similarity 124B

chr5_+_137203559 0.480 MYOT
myotilin
chr2_-_224467095 0.476 SCG2
secretogranin II
chr9_+_91003987 0.476 SPIN1
spindlin 1
chr17_-_19648924 0.474 NM_001135167
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr9_-_73483933 0.473 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr20_+_11898536 0.471 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr7_-_44887663 0.471 H2AFV
H2A histone family, member V
chr17_+_61851512 0.471


chr16_-_73082169 0.469 NM_006885
ZFHX3
zinc finger homeobox 3
chr5_-_39424930 0.467 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr7_-_47622127 0.465 TNS3
tensin 3
chr5_+_138677546 0.465 PAIP2
poly(A) binding protein interacting protein 2
chr6_+_119215240 0.463 NM_014034
ASF1A
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr8_-_93029864 0.459 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_137203544 0.459 NM_001135940
NM_006790
MYOT

myotilin

chr9_-_89562103 0.459 NM_002048
GAS1
growth arrest-specific 1
chr5_-_146833150 0.457 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr5_-_39425297 0.455 NM_001244871
NM_001343
DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

chr5_+_67588395 0.450 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr2_-_224467049 0.450 SCG2
secretogranin II
chr8_-_72273965 0.448 EYA1
eyes absent homolog 1 (Drosophila)
chr2_+_152214105 0.447 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_+_140739589 0.447 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr2_-_214015053 0.445 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr3_+_154797644 0.444 NM_007287
MME
membrane metallo-endopeptidase
chr7_+_134464417 0.442 CALD1
caldesmon 1
chr16_+_69726751 0.440 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr7_-_19157262 0.440 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr5_-_172198160 0.440 NM_004417
DUSP1
dual specificity phosphatase 1
chr2_-_224467142 0.439 NM_003469
SCG2
secretogranin II
chr5_+_81601165 0.438 NM_001017971
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr3_+_154797435 0.438 NM_000902
MME
membrane metallo-endopeptidase
chr6_-_152957985 0.437 NM_033071
SYNE1
spectrin repeat containing, nuclear envelope 1
chr3_-_48700317 0.436 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr12_+_13349716 0.435 EMP1
epithelial membrane protein 1
chr5_-_14871555 0.433 NM_054027
ANKH
ankylosis, progressive homolog (mouse)
chrX_-_135863033 0.429 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chrX_-_135863502 0.428 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr10_+_104535887 0.428 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr5_+_172483285 0.428 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr19_-_44831907 0.425 ZFP112
zinc finger protein 112 homolog (mouse)
chr6_-_85473898 0.424 NM_001080508
TBX18
T-box 18
chr16_+_55515468 0.423 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.33 2.02e-11 GO:0032502 developmental process
1.20 1.13e-09 GO:0050794 regulation of cellular process
1.33 1.82e-09 GO:0007275 multicellular organismal development
1.43 2.49e-09 GO:0048523 negative regulation of cellular process
1.18 3.82e-09 GO:0050789 regulation of biological process
1.34 4.43e-09 GO:0048856 anatomical structure development
1.40 1.24e-08 GO:0048519 negative regulation of biological process
1.17 2.10e-08 GO:0065007 biological regulation
1.51 3.31e-08 GO:0009653 anatomical structure morphogenesis
1.33 2.27e-07 GO:0048731 system development
1.78 6.57e-07 GO:0010629 negative regulation of gene expression
1.47 7.95e-07 GO:0007399 nervous system development
1.71 1.15e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.76 1.38e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.30 1.47e-05 GO:0048518 positive regulation of biological process
1.74 2.15e-05 GO:0051253 negative regulation of RNA metabolic process
1.71 2.27e-05 GO:0000902 cell morphogenesis
1.78 2.42e-05 GO:0000904 cell morphogenesis involved in differentiation
1.32 2.43e-05 GO:0048522 positive regulation of cellular process
1.68 3.41e-05 GO:0032989 cellular component morphogenesis
1.66 4.63e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.34 4.83e-05 GO:0048869 cellular developmental process
1.62 1.52e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.33 1.53e-04 GO:0030154 cell differentiation
1.52 1.86e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.25 2.01e-04 GO:0016043 cellular component organization
1.53 2.25e-04 GO:0006351 transcription, DNA-dependent
1.71 2.80e-04 GO:0048858 cell projection morphogenesis
1.29 3.72e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.30 3.95e-04 GO:0051252 regulation of RNA metabolic process
1.77 4.00e-04 GO:0007409 axonogenesis
1.70 4.31e-04 GO:0032990 cell part morphogenesis
1.18 4.41e-04 GO:0032501 multicellular organismal process
1.58 5.01e-04 GO:0009890 negative regulation of biosynthetic process
1.28 5.20e-04 GO:0010468 regulation of gene expression
1.28 7.15e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.47 7.89e-04 GO:0009892 negative regulation of metabolic process
1.49 8.97e-04 GO:0022008 neurogenesis
1.73 9.82e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.30 1.01e-03 GO:0006355 regulation of transcription, DNA-dependent
1.72 1.07e-03 GO:0048812 neuron projection morphogenesis
1.61 1.18e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49 1.26e-03 GO:0031324 negative regulation of cellular metabolic process
1.50 1.52e-03 GO:0048699 generation of neurons
1.58 1.63e-03 GO:0030030 cell projection organization
1.22 1.84e-03 GO:0007165 signal transduction
1.84 1.94e-03 GO:0001501 skeletal system development
1.59 2.24e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.22 2.38e-03 GO:0071840 cellular component organization or biogenesis
1.46 2.53e-03 GO:0032774 RNA biosynthetic process
1.31 3.03e-03 GO:0048513 organ development
1.22 3.11e-03 GO:0060255 regulation of macromolecule metabolic process
1.19 3.16e-03 GO:0051716 cellular response to stimulus
1.45 3.35e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.21 3.48e-03 GO:0023052 signaling
1.34 4.01e-03 GO:0023051 regulation of signaling
1.46 4.05e-03 GO:0048468 cell development
1.63 6.05e-03 GO:0031175 neuron projection development
1.25 8.02e-03 GO:0071842 cellular component organization at cellular level
1.69 9.73e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.35 1.04e-02 GO:0009966 regulation of signal transduction
1.47 1.20e-02 GO:0051128 regulation of cellular component organization
1.07 1.36e-02 GO:0009987 cellular process
1.51 1.37e-02 GO:0030182 neuron differentiation
1.80 1.66e-02 GO:0030029 actin filament-based process
1.20 1.66e-02 GO:0031323 regulation of cellular metabolic process
1.55 1.88e-02 GO:0048666 neuron development
1.44 2.04e-02 GO:0040011 locomotion
1.19 2.32e-02 GO:0080090 regulation of primary metabolic process
1.50 2.50e-02 GO:0010628 positive regulation of gene expression
1.23 2.87e-02 GO:0031326 regulation of cellular biosynthetic process
1.34 2.98e-02 GO:0035556 intracellular signal transduction
2.13 4.08e-02 GO:0007156 homophilic cell adhesion
2.96 4.11e-02 GO:0001764 neuron migration
1.51 4.16e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.22 4.51e-02 GO:0009889 regulation of biosynthetic process
1.46 4.51e-02 GO:2000026 regulation of multicellular organismal development
2.50 4.62e-02 GO:0048706 embryonic skeletal system development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.24 1.35e-11 GO:0005634 nucleus
1.08 2.39e-05 GO:0044424 intracellular part
1.08 2.72e-05 GO:0005622 intracellular
1.10 1.72e-04 GO:0043229 intracellular organelle
1.10 2.16e-04 GO:0043226 organelle
2.33 1.47e-03 GO:0044420 extracellular matrix part
1.10 1.81e-03 GO:0043231 intracellular membrane-bounded organelle
1.10 2.30e-03 GO:0043227 membrane-bounded organelle
1.72 4.47e-03 GO:0005578 proteinaceous extracellular matrix
2.58 8.37e-03 GO:0005604 basement membrane
2.21 1.27e-02 GO:0030055 cell-substrate junction
1.62 1.33e-02 GO:0031012 extracellular matrix
2.24 1.77e-02 GO:0005925 focal adhesion
3.20 2.04e-02 GO:0005581 collagen
2.35 2.07e-02 GO:0030027 lamellipodium
2.13 4.47e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 4.44e-12 GO:0005488 binding
1.19 1.23e-10 GO:0005515 protein binding
1.58 1.03e-07 GO:0001071 nucleic acid binding transcription factor activity
1.58 1.03e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.55 7.65e-07 GO:0030528 transcription regulator activity
1.29 9.15e-05 GO:0003677 DNA binding
1.21 1.81e-03 GO:0003676 nucleic acid binding
1.51 2.10e-03 GO:0043565 sequence-specific DNA binding
3.11 7.72e-03 GO:0008013 beta-catenin binding
1.53 9.18e-03 GO:0008092 cytoskeletal protein binding
1.68 1.64e-02 GO:0003779 actin binding