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• Activity deltas table
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Motif ID: HLF.p2

Z-value: 1.257

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_52845862	2.938	NM_005555	KRT6B	keratin 6B
chr2_+_113885137	2.655	NM_173842	IL1RN	interleukin 1 receptor antagonist
chr8_+_124194751	2.639	NM_032899 NM_207006	FAM83A	family with sequence similarity 83, member A
chr8_+_124194873	2.563		FAM83A	family with sequence similarity 83, member A
chr2_-_113594325	2.460	NM_000576	IL1B	interleukin 1, beta
chr19_-_35992798	2.140	NM_001035516	DMKN	dermokine
chr12_-_28124915	2.096	NM_002820 NM_198965	PTHLH	parathyroid hormone-like hormone
chr18_+_61554938	2.016	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr5_+_140247767	1.773	NM_018902 NM_031861	PCDHA11	protocadherin alpha 11
chr10_-_116444374	1.711	NM_001003407 NM_001003408	ABLIM1	actin binding LIM protein 1
chr14_+_96722546	1.710	NM_000710	BDKRB1	bradykinin receptor B1
chr2_+_113885145	1.519		IL1RN	interleukin 1 receptor antagonist
chr10_-_116444112	1.436		ABLIM1	actin binding LIM protein 1
chr11_+_18287807	1.323	NM_000331 NM_001178006 NM_199161	SAA1	serum amyloid A1
chr20_+_58630965	1.247	NM_173644	C20orf197	chromosome 20 open reading frame 197
chr12_+_29376596	1.171	NM_018099	FAR2	fatty acyl CoA reductase 2
chr20_+_58296264	1.133	NM_183244 NM_183246	PHACTR3	phosphatase and actin regulator 3
chr16_+_57406398	1.124	NM_002996	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr7_-_83824216	1.084	NM_006080	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr5_+_36606456	1.008	NM_001166696 NM_004172	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_-_117251302	0.989	NM_001168301	KLHL13	kelch-like 13 (Drosophila)
chr6_-_2840683	0.957		SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr2_-_31637598	0.956	NM_000379	XDH	xanthine dehydrogenase
chr2_-_31637553	0.949		XDH	xanthine dehydrogenase
chrX_-_33229428	0.906	NM_004006	DMD	dystrophin
chr5_+_140254930	0.904	NM_018903 NM_031864	PCDHA12	protocadherin alpha 12
chr18_+_61254533	0.879	NM_012397	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr5_+_36606667	0.857		SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_-_41623246	0.736	NM_001986	ETV4	ets variant 4
chr17_+_34431219	0.730	NM_002984	CCL4	chemokine (C-C motif) ligand 4
chr14_+_96671015	0.723	NM_000623	BDKRB2	bradykinin receptor B2
chr15_-_83621350	0.706	NM_004839 NM_199330	HOMER2	homer homolog 2 (Drosophila)
chr1_-_62785067	0.665	NM_181712	KANK4	KN motif and ankyrin repeat domains 4
chr12_-_105322056	0.663	NM_032148	SLC41A2	solute carrier family 41, member 2
chr20_-_43883183	0.636	NM_003064	SLPI	secretory leukocyte peptidase inhibitor
chr5_+_149151502	0.631	NM_001172699	PPARGC1B	peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr3_+_122044010	0.611	NM_005213	CSTA	cystatin A (stefin A)
chr15_-_63674074	0.593	NM_001218 NM_206925	CA12	carbonic anhydrase XII
chr6_-_30043547	0.590	NM_170769 NM_025236	RNF39	ring finger protein 39
chr17_-_39274587	0.570	NM_033059	KRTAP4-11	keratin associated protein 4-11
chr8_-_130799133	0.570	NM_031415	GSDMC	gasdermin C
chr17_-_39538635	0.566	NM_021013	KRT34	keratin 34
chr16_+_68057144	0.557	NM_017803	DUS2L	dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)
chr2_+_191002485	0.535	NM_001042521	C2orf88	chromosome 2 open reading frame 88
chr1_-_62784971	0.526		KANK4	KN motif and ankyrin repeat domains 4
chr4_-_153273683	0.524	NM_018315	FBXW7	F-box and WD repeat domain containing 7
chr4_+_71200670	0.523	NM_033122	CABS1	calcium-binding protein, spermatid-specific 1
chr11_-_18270167	0.507	NM_001199744 NM_001127380 NM_030754	SAA2-SAA4 SAA2	SAA2-SAA4 readthrough serum amyloid A2
chr10_-_45474210	0.503	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr12_-_123201319	0.502	NM_006018	HCAR3	hydroxycarboxylic acid receptor 3
chr5_-_140012730	0.498		CD14	CD14 molecule
chr3_-_151034514	0.498	NM_023915	GPR87	G protein-coupled receptor 87
chr18_+_55888799	0.490		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr2_-_38525527	0.484		ATL2	atlastin GTPase 2
chr11_+_112047088	0.467	NM_001037290	BCO2	beta-carotene oxygenase 2
chr14_-_23284617	0.461		SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_-_41388656	0.461	NM_000764 NM_030589	CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7
chr3_-_121264780	0.459	NM_199420	POLQ	polymerase (DNA directed), theta
chr17_-_41277409	0.455	NM_007297 NM_007299 NM_007294 NM_007300	BRCA1	breast cancer 1, early onset
chr14_-_23284565	0.452		SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr12_-_123380682	0.447	NM_024667	VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr1_+_196857143	0.435	NM_001201550 NM_001201551 NM_006684	CFHR4	complement factor H-related 4
chr4_-_100485173	0.432	NM_001134665 NM_001134666	RG9MTD2	RNA (guanine-9-) methyltransferase domain containing 2
chr3_+_142342265	0.431	NM_002670	PLS1	plastin 1
chr10_+_103911932	0.430	NM_004741	NOLC1	nucleolar and coiled-body phosphoprotein 1
chr19_+_45504686	0.429	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr5_-_140013034	0.416	NM_000591	CD14	CD14 molecule
chr17_-_17485691	0.415		PEMT	phosphatidylethanolamine N-methyltransferase
chr7_+_143880547	0.414	NM_198495	CTAGE4 CTAGE8	CTAGE family, member 4 CTAGE family, member 8
chr12_-_123380628	0.402		VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr16_-_68057098	0.400		DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr5_+_36608430	0.392	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_+_90032647	0.392	NM_001185072 NM_001185073 NM_012129	CLDN12	claudin 12
chrX_+_41306686	0.387	NM_022567	NYX	nyctalopin
chrY_+_3447081	0.380	NM_139214	TGIF2LY	TGFB-induced factor homeobox 2-like, Y-linked
chr18_+_77866914	0.375	NM_014913	ADNP2	ADNP homeobox 2
chr10_+_123923104	0.375	NM_006997 NM_206860	TACC2	transforming, acidic coiled-coil containing protein 2
chr9_-_117156684	0.360	NM_030767	AKNA	AT-hook transcription factor
chr3_-_143567163	0.360	NM_173653	SLC9A9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr7_-_143966380	0.359	NM_198495	CTAGE4 CTAGE8	CTAGE family, member 4 CTAGE family, member 8
chr17_-_17485744	0.350	NM_007169	PEMT	phosphatidylethanolamine N-methyltransferase
chr12_-_71148383	0.350	NM_130846 NM_001207016	PTPRR	protein tyrosine phosphatase, receptor type, R
chr12_-_123187842	0.344	NM_177551	HCAR2	hydroxycarboxylic acid receptor 2
chr6_-_52109226	0.341	NM_052872	IL17F	interleukin 17F
chr10_+_47746919	0.340	NM_001630	ANXA8L2 ANXA8	annexin A8-like 2 annexin A8
chr1_-_178840079	0.340	NM_004673	ANGPTL1	angiopoietin-like 1
chr10_+_74653338	0.338	NM_152635	OIT3	oncoprotein induced transcript 3
chr10_+_99496891	0.338		ZFYVE27	zinc finger, FYVE domain containing 27
chr6_-_132032156	0.334	NM_001145659	CTAGE9	CTAGE family, member 9
chr7_+_90032771	0.334		CLDN12	claudin 12
chr19_+_10362886	0.326		MRPL4	mitochondrial ribosomal protein L4
chr1_-_151032036	0.318		CDC42SE1	CDC42 small effector 1
chr17_-_7155258	0.318	NM_015343	CTDNEP1	CTD nuclear envelope phosphatase 1
chr6_-_119252887	0.318	NM_017696	MCM9	minichromosome maintenance complex component 9
chr5_+_150632612	0.317	NM_000405 NM_001167607	GM2A	GM2 ganglioside activator
chr13_-_75901897	0.317		TBC1D4	TBC1 domain family, member 4
chr12_-_71031174	0.316	NM_001109754	PTPRB	protein tyrosine phosphatase, receptor type, B
chr17_-_56494930	0.315	NM_017763	RNF43	ring finger protein 43
chr17_-_26127395	0.311		NOS2	nitric oxide synthase 2, inducible
chr19_-_41356193	0.311	NM_000762	CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6
chr18_+_55816546	0.310	NM_001144965 NM_001144968 NM_001144969 NM_001144971	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr11_+_69061599	0.309	NM_138768	MYEOV	myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr17_-_41322211	0.307		BRCA1	breast cancer 1, early onset
chr6_+_121756744	0.305	NM_000165	GJA1	gap junction protein, alpha 1, 43kDa
chrX_+_102585113	0.304	NM_152278	TCEAL7	transcription elongation factor A (SII)-like 7
chr8_-_86253863	0.300	NM_001164830	CA1	carbonic anhydrase I
chr1_-_67266930	0.299	NM_005478	INSL5	insulin-like 5
chr10_+_114043413	0.296	NM_058222	TECTB	tectorin beta
chr5_+_55149149	0.296	NM_001242636 NM_001242639	IL31RA	interleukin 31 receptor A
chr11_+_10477480	0.294	NM_001025390	AMPD3	adenosine monophosphate deaminase 3
chr18_+_29598444	0.286	NM_017831	RNF125	ring finger protein 125
chr15_+_40509628	0.286	NM_001128628 NM_001128629	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr1_+_212738675	0.285	NM_001030287	ATF3	activating transcription factor 3
chrX_-_13338517	0.285	NM_001135995	ATXN3L	ataxin 3-like
chr18_+_55888838	0.283		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr1_-_109935869	0.282	NM_001205228	SORT1	sortilin 1
chr4_-_170924911	0.277	NM_001009554	MFAP3L	microfibrillar-associated protein 3-like
chr10_+_99496938	0.277		ZFYVE27	zinc finger, FYVE domain containing 27
chr19_-_49250023	0.276	NM_182575	IZUMO1	izumo sperm-egg fusion 1
chr9_-_125941304	0.275		STRBP	spermatid perinuclear RNA binding protein
chr14_+_68086655	0.274		ARG2	arginase, type II
chr4_+_128802064	0.273	NM_001190801	PLK4	polo-like kinase 4
chr8_-_42397048	0.272	NM_006749	SLC20A2	solute carrier family 20 (phosphate transporter), member 2
chr20_+_55099784	0.271	NM_001012971	FAM209A FAM209B	family with sequence similarity 209, member A family with sequence similarity 209, member B
chr5_+_6746100	0.271	NM_001171806	PAPD7	PAP associated domain containing 7
chr8_+_120079423	0.271	NM_006438	COLEC10	collectin sub-family member 10 (C-type lectin)
chr20_+_36011936	0.270		SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr6_+_90276556	0.270	NM_001242814	ANKRD6	ankyrin repeat domain 6
chr19_+_10362912	0.269		MRPL4	mitochondrial ribosomal protein L4
chr20_+_30028410	0.265	NM_153324	DEFB123	defensin, beta 123
chr18_+_55888750	0.264	NM_001144966	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr2_+_201756639	0.263	NM_001142356	NIF3L1	NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr19_-_2042022	0.262		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr3_+_189349215	0.260	NM_001114978 NM_001114979 NM_003722	TP63	tumor protein p63
chrX_-_118699318	0.260	NM_001170569	CXorf56	chromosome X open reading frame 56
chr17_-_41277304	0.257		BRCA1	breast cancer 1, early onset
chr1_+_241815579	0.257	NM_144625	WDR64	WD repeat domain 64
chr8_+_98788014	0.257		LAPTM4B	lysosomal protein transmembrane 4 beta
chr19_-_40919270	0.256	NM_020956 NM_181882	PRX	periaxin
chr1_+_7844713	0.256	NM_016831	PER3	period homolog 3 (Drosophila)
chr16_-_68057120	0.256		DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr11_+_112046207	0.255	NM_031938	BCO2	beta-carotene oxygenase 2
chr12_-_52604488	0.254	NM_001242696	LOC283403	uncharacterized LOC283403
chr7_-_31380507	0.253	NM_022728	NEUROD6	neurogenic differentiation 6
chr1_-_93342706	0.248	NM_001252271	FAM69A	family with sequence similarity 69, member A
chr11_-_33795892	0.247	NM_012175 NM_033406	FBXO3	F-box protein 3
chr20_+_16728997	0.246	NM_020157	OTOR	otoraplin
chr10_-_101190201	0.245	NM_002079	GOT1	glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chr14_-_23285011	0.243	NM_001126105	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_-_114429996	0.242		BCL2L15	BCL2-like 15
chr15_-_72598655	0.240	NM_001172685	CELF6	CUGBP, Elav-like family member 6
chr15_-_63673918	0.237		CA12	carbonic anhydrase XII
chr12_+_112856756	0.237		PTPN11	protein tyrosine phosphatase, non-receptor type 11
chr16_+_31711914	0.236		KIAA0664L3	KIAA0664-like 3
chr1_-_114430168	0.230	NM_001010922	BCL2L15	BCL2-like 15
chr19_+_49259343	0.227	NM_019113	FGF21	fibroblast growth factor 21
chr13_-_25746304	0.227		FAM123A	family with sequence similarity 123A
chr2_+_179184970	0.225	NM_145739	OSBPL6	oxysterol binding protein-like 6
chr9_-_2844098	0.224	NM_014878	KIAA0020	KIAA0020
chr9_-_2844083	0.223		KIAA0020	KIAA0020
chr17_-_34270670	0.222	NM_001199951	LYZL6	lysozyme-like 6
chr9_-_117160748	0.220		AKNA	AT-hook transcription factor
chr2_+_65663812	0.220		FLJ16124	FLJ16124 protein
chr1_+_152956563	0.219	NM_001199828 NM_005987	SPRR1A	small proline-rich protein 1A
chr11_-_18062304	0.219	NM_004179	TPH1	tryptophan hydroxylase 1
chr18_+_77155943	0.217		NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr17_-_39324423	0.217	NM_033187	KRTAP4-3	keratin associated protein 4-3
chr6_-_134373618	0.215	NM_145176	SLC2A12	solute carrier family 2 (facilitated glucose transporter), member 12
chr6_-_24383519	0.214	NM_001195610	DCDC2	doublecortin domain containing 2
chr12_-_8043743	0.214		SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14
chr14_-_24732344	0.214	NM_000359	TGM1	transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
chr16_+_9185534	0.213	NM_014117	C16orf72	chromosome 16 open reading frame 72
chr3_+_142375738	0.213	NM_001172312	PLS1	plastin 1
chr11_-_123525300	0.210	NM_001040151 NM_018400	SCN3B	sodium channel, voltage-gated, type III, beta
chr20_+_23471765	0.209	NM_005492	CST8	cystatin 8 (cystatin-related epididymal specific)
chr8_-_66701175	0.207	NM_002603	PDE7A	phosphodiesterase 7A
chr18_-_13726582	0.207	NM_001098801 NM_152352	FAM210A	family with sequence similarity 210, member A
chr7_+_115863004	0.207	NM_152829	TES	testis derived transcript (3 LIM domains)
chr5_-_53606387	0.205	NM_019087	ARL15	ADP-ribosylation factor-like 15
chr1_+_158150678	0.204		CD1D	CD1d molecule
chr1_-_247054277	0.204		AHCTF1	AT hook containing transcription factor 1
chr8_-_125579395	0.204		MTSS1	metastasis suppressor 1
chr18_+_13726658	0.195	NM_003799	RNMT	RNA (guanine-7-) methyltransferase
chr4_+_128802015	0.195	NM_001190799 NM_014264	PLK4	polo-like kinase 4
chr6_+_7402879	0.194	NM_153005	RIOK1	RIO kinase 1 (yeast)
chr17_+_57297827	0.192	NM_001165993 NM_001165994 NM_182569	GDPD1	glycerophosphodiester phosphodiesterase domain containing 1
chr16_+_30034654	0.190	NM_001109659 NM_001109660	C16orf92	chromosome 16 open reading frame 92
chr19_-_53770917	0.189	NM_173857	VN1R4	vomeronasal 1 receptor 4
chr13_-_25745620	0.188		FAM123A	family with sequence similarity 123A
chr8_+_98787808	0.185	NM_018407	LAPTM4B	lysosomal protein transmembrane 4 beta
chr12_+_112856701	0.184		PTPN11	protein tyrosine phosphatase, non-receptor type 11
chr17_-_26941178	0.184	NM_001174103	SGK494	uncharacterized serine/threonine-protein kinase SgK494
chr11_+_3818953	0.184	NM_001145438	PGAP2	post-GPI attachment to proteins 2
chr6_+_150690027	0.183	NM_001164694 NM_001164695 NM_203395	IYD	iodotyrosine deiodinase
chr19_-_18314731	0.182	NM_002866	RAB3A	RAB3A, member RAS oncogene family
chr7_-_37956515	0.182	NM_003014	SFRP4	secreted frizzled-related protein 4
chr16_+_31711926	0.182		KIAA0664L3	KIAA0664-like 3
chr3_-_196911001	0.180	NM_001204387 NM_001204388	DLG1	discs, large homolog 1 (Drosophila)
chrX_-_72434623	0.180		NAP1L2	nucleosome assembly protein 1-like 2
chr1_-_161147757	0.178	NM_001199873 NM_001199874 NM_003779	B4GALT3	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
15.46	1.38e-03	GO:0060600	dichotomous subdivision of an epithelial terminal unit
17.71	5.07e-03	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching
15.74	1.11e-02	GO:0048880	sensory system development
15.74	1.11e-02	GO:0048892	lateral line nerve development
15.74	1.11e-02	GO:0048895	lateral line nerve glial cell differentiation
15.74	1.11e-02	GO:0048925	lateral line system development
15.74	1.11e-02	GO:0048937	lateral line nerve glial cell development
15.74	1.11e-02	GO:0050935	iridophore differentiation
11.34	1.32e-02	GO:0048485	sympathetic nervous system development
2.66	1.68e-02	GO:0006954	inflammatory response
10.63	2.06e-02	GO:0015721	bile acid and bile salt transport

Nothing significant found in compartment category.

Nothing significant found in function category.