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• Activity deltas table
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Motif ID: HOXA9_MEIS1.p2

Z-value: 0.522

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_165424993	0.414		GRB14	growth factor receptor-bound protein 14
chr14_-_94856926	0.394	NM_001002235 NM_001002236 NM_001127700 NM_001127701 NM_001127702 NM_001127703 NM_001127704 NM_001127705 NM_001127706 NM_001127707	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr5_+_68800003	0.383	NM_001205255	OCLN	occludin
chr6_+_29274402	0.366	NM_030946	OR14J1	olfactory receptor, family 14, subfamily J, member 1
chr16_+_4838397	0.361	NM_001253790 NM_001253791	LOC440335	uncharacterized LOC440335
chr13_+_78109808	0.325	NM_001160706 NM_003843 NM_144777	SCEL	sciellin
chr2_-_161056573	0.290	NM_000888	ITGB6	integrin, beta 6
chr5_+_140261792	0.263	NM_018904 NM_031865	PCDHA13	protocadherin alpha 13
chr7_+_73245192	0.246	NM_001305	CLDN4	claudin 4
chr4_-_53617781	0.241	NM_001242690 NM_024534	ERVMER34-1	endogenous retrovirus group MER34, member 1
chr17_-_46608271	0.236	NM_002144	HOXB1	homeobox B1
chr3_-_27498244	0.232	NM_003615	SLC4A7	solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr17_+_16120465	0.225	NM_004278	PIGL	phosphatidylinositol glycan anchor biosynthesis, class L
chr19_-_44174497	0.223	NM_001005376 NM_001005377 NM_002659	PLAUR	plasminogen activator, urokinase receptor
chr1_-_115238091	0.214	NM_000036 NM_001172626	AMPD1	adenosine monophosphate deaminase 1
chr20_+_9458460	0.214		PLCB4	phospholipase C, beta 4
chr15_+_66694216	0.209		MAP2K1	mitogen-activated protein kinase kinase 1
chr2_-_113594325	0.199	NM_000576	IL1B	interleukin 1, beta
chr3_-_190167597	0.190	NM_207316	TMEM207	transmembrane protein 207
chr7_+_115863004	0.182	NM_152829	TES	testis derived transcript (3 LIM domains)
chr4_-_166034003	0.175	NM_001100389	TMEM192	transmembrane protein 192
chr3_+_130569368	0.172	NM_001199180 NM_001199181 NM_001199182	ATP2C1	ATPase, Ca++ transporting, type 2C, member 1
chr12_+_78225068	0.165	NM_014903	NAV3	neuron navigator 3
chr12_-_51422012	0.162	NM_001174125	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr8_-_17555158	0.158	NM_020749	MTUS1	microtubule associated tumor suppressor 1
chr9_+_93589704	0.154	NM_001174167	SYK	spleen tyrosine kinase
chr4_-_166033924	0.154		TMEM192	transmembrane protein 192
chr17_-_29641094	0.145	NM_006495	EVI2B	ecotropic viral integration site 2B
chr14_+_68168602	0.144	NM_152443	RDH12	retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr1_+_2005424	0.142	NM_001242874	PRKCZ	protein kinase C, zeta
chr5_+_145316120	0.139	NM_152550	SH3RF2	SH3 domain containing ring finger 2
chr18_+_9885722	0.129	NM_001098529 NM_032243	TXNDC2	thioredoxin domain containing 2 (spermatozoa)
chr10_+_98740987	0.127	NM_015652	C10orf12	chromosome 10 open reading frame 12
chr12_+_8975149	0.127	NM_144670	A2ML1	alpha-2-macroglobulin-like 1
chr4_+_69313166	0.124	NM_014058	TMPRSS11E	transmembrane protease, serine 11E
chr19_+_10828813	0.119		DNM2	dynamin 2
chr6_-_52109226	0.119	NM_052872	IL17F	interleukin 17F
chr4_+_88896899	0.117		SPP1	secreted phosphoprotein 1
chr17_-_29641087	0.116		EVI2B	ecotropic viral integration site 2B
chr8_+_143781527	0.110	NM_001160354 NM_001160355 NM_017527	LY6K	lymphocyte antigen 6 complex, locus K
chr4_-_40516567	0.106		RBM47	RNA binding motif protein 47
chr9_+_125281418	0.105	NM_001004452	OR1J4	olfactory receptor, family 1, subfamily J, member 4
chr19_+_10828725	0.100	NM_001005360 NM_001005361 NM_001005362 NM_001190716 NM_004945	DNM2	dynamin 2
chr16_+_88636818	0.097		ZC3H18	zinc finger CCCH-type containing 18
chr1_-_247171302	0.096		ZNF695	zinc finger protein 695
chr9_+_130911731	0.093	NM_005564	LCN2	lipocalin 2
chr5_+_132432880	0.091		HSPA4	heat shock 70kDa protein 4
chr4_-_122137781	0.089	NM_001128843	TNIP3	TNFAIP3 interacting protein 3
chr12_-_53343607	0.089		KRT8	keratin 8
chr6_+_125304509	0.088	NM_152553	RNF217	ring finger protein 217
chr6_-_29343063	0.087	NM_030959	OR12D3	olfactory receptor, family 12, subfamily D, member 3
chr3_-_168864325	0.085	NM_001105078	MECOM	MDS1 and EVI1 complex locus
chr17_-_56492938	0.084		RNF43	ring finger protein 43
chr19_-_49567123	0.084	NM_006179	NTF4	neurotrophin 4
chr3_-_56809594	0.083	NM_001128616	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chr11_+_71846755	0.083	NM_000804	FOLR3	folate receptor 3 (gamma)
chr19_+_15052298	0.082	NM_012377	OR7C2	olfactory receptor, family 7, subfamily C, member 2
chr12_+_41086189	0.082	NM_001843 NM_175038	CNTN1	contactin 1
chr19_-_15590203	0.080	NM_052890	PGLYRP2	peptidoglycan recognition protein 2
chr19_+_10828763	0.080		DNM2	dynamin 2
chr19_+_10828772	0.076		DNM2	dynamin 2
chr4_+_71494460	0.075	NM_031889	ENAM	enamelin
chr17_-_38210888	0.074	NM_001079518 NM_014815	MED24	mediator complex subunit 24
chr19_-_14910947	0.073	NM_198944	OR7C1	olfactory receptor, family 7, subfamily C, member 1
chr3_+_82035288	0.072
chr18_+_20735788	0.071	NM_138375	CABLES1	Cdk5 and Abl enzyme substrate 1
chr4_-_128887092	0.070	NM_152778	MFSD8	major facilitator superfamily domain containing 8
chr16_+_88636841	0.069		ZC3H18	zinc finger CCCH-type containing 18
chr3_+_111717585	0.068	NM_001008272 NM_013259	TAGLN3	transgelin 3
chr2_+_115199898	0.068	NM_020868	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr11_-_16430425	0.066	NM_001145811	SOX6	SRY (sex determining region Y)-box 6
chr16_+_88636810	0.066		ZC3H18	zinc finger CCCH-type containing 18
chr12_-_120765555	0.066	NM_000928	PLA2G1B	phospholipase A2, group IB (pancreas)
chr16_+_88636657	0.065	NM_144604	ZC3H18	zinc finger CCCH-type containing 18
chr11_+_27062508	0.065	NM_003986	BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr8_-_6420454	0.065	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr4_-_83347778	0.065		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr4_+_39408472	0.064	NM_175737	KLB	klotho beta
chr2_+_68592432	0.064		PLEK	pleckstrin
chr8_-_124408665	0.063		ATAD2	ATPase family, AAA domain containing 2
chr3_-_150966901	0.063	NM_001081455	P2RY14	purinergic receptor P2Y, G-protein coupled, 14
chr15_+_45028559	0.062	NM_080745 NM_182985	TRIM69	tripartite motif containing 69
chr4_+_88896801	0.062	NM_000582 NM_001040058 NM_001040060 NM_001251829 NM_001251830	SPP1	secreted phosphoprotein 1
chr2_+_219724545	0.060	NM_006522	WNT6	wingless-type MMTV integration site family, member 6
chr18_+_72166568	0.057		CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr5_-_137071703	0.054	NM_017415	KLHL3	kelch-like 3 (Drosophila)
chrX_-_32430370	0.053	NM_004011 NM_004012	DMD	dystrophin
chr18_-_22930826	0.052
chr14_-_95599794	0.050	NM_001195573	DICER1	dicer 1, ribonuclease type III
chr2_+_88824168	0.050	NM_152670	C2orf51	chromosome 2 open reading frame 51
chr2_+_204732509	0.049	NM_001037631 NM_005214	CTLA4	cytotoxic T-lymphocyte-associated protein 4
chr13_+_96329392	0.048	NM_006260	DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3
chrX_+_123234462	0.047		STAG2	stromal antigen 2
chr7_-_50628744	0.046	NM_000790 NM_001242886 NM_001242887 NM_001242888 NM_001242889 NM_001242890	DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr19_-_39235113	0.046	NM_144691	CAPN12	calpain 12
chr21_-_32253843	0.045	NM_175858	KRTAP11-1	keratin associated protein 11-1
chr18_-_52969714	0.045	NM_001243236	TCF4	transcription factor 4
chr7_+_80267782	0.045	NM_000072 NM_001001548	CD36	CD36 molecule (thrombospondin receptor)
chr1_-_247921707	0.045	NM_012353	OR1C1	olfactory receptor, family 1, subfamily C, member 1
chr8_-_124408688	0.043	NM_014109	ATAD2	ATPase family, AAA domain containing 2
chrM_+_11723	0.043
chr12_-_46384208	0.042		SCAF11	SR-related CTD-associated factor 11
chr17_+_17608163	0.042
chrX_+_100474932	0.041	NM_001171184 NM_001939	DRP2	dystrophin related protein 2
chr7_+_44646120	0.040	NM_001003941 NM_001165036 NM_002541	OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr18_+_56530060	0.040	NM_018181	ZNF532	zinc finger protein 532
chr1_+_24649529	0.039	NM_021180	GRHL3	grainyhead-like 3 (Drosophila)
chr18_-_31628557	0.039	NM_001198549	NOL4	nucleolar protein 4
chr12_-_121342050	0.039	NM_139015	SPPL3	signal peptide peptidase-like 3
chrX_-_110654373	0.039	NM_000555	DCX	doublecortin
chr18_+_72166822	0.039	NM_001168499	CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr12_-_16757944	0.038		LMO3	LIM domain only 3 (rhombotin-like 2)
chr7_+_63774378	0.038		ZNF736	zinc finger protein 736
chr12_-_9268475	0.038		A2M	alpha-2-macroglobulin
chr8_-_101965554	0.038		YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr21_+_46117086	0.037	NM_198699	KRTAP10-12	keratin associated protein 10-12
chr7_+_128578246	0.036	NM_032643	IRF5	interferon regulatory factor 5
chr15_-_43559054	0.035	NM_004245 NM_201631	TGM5	transglutaminase 5
chr9_+_90497740	0.035	NM_178828	C9orf79	chromosome 9 open reading frame 79
chr7_+_136553398	0.035	NM_001006627 NM_001006630	CHRM2	cholinergic receptor, muscarinic 2
chr18_+_2655885	0.035	NM_015295	SMCHD1	structural maintenance of chromosomes flexible hinge domain containing 1
chr1_+_171481164	0.035		PRRC2C	proline-rich coiled-coil 2C
chr11_-_7847518	0.034	NM_153445	OR5P3	olfactory receptor, family 5, subfamily P, member 3
chr2_-_225370687	0.033		CUL3	cullin 3
chr18_+_55816546	0.033	NM_001144965 NM_001144968 NM_001144969 NM_001144971	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chrX_+_78003205	0.033	NM_005296	LPAR4	lysophosphatidic acid receptor 4
chr3_-_150996153	0.033	NM_014879	P2RY14	purinergic receptor P2Y, G-protein coupled, 14
chr21_-_34185943	0.031	NM_001162495 NM_001162496 NM_019596	C21orf62	chromosome 21 open reading frame 62
chr6_-_49604524	0.030	NM_000324	RHAG	Rh-associated glycoprotein
chr5_+_126984712	0.030	NM_001048252	CTXN3	cortexin 3
chr1_-_169599349	0.029	NM_003005	SELP	selectin P (granule membrane protein 140kDa, antigen CD62)
chr13_+_32313678	0.029	NM_001166058 NM_130806	RXFP2	relaxin/insulin-like family peptide receptor 2
chr10_+_123754141	0.029		TACC2	transforming, acidic coiled-coil containing protein 2
chr3_-_193096513	0.028	NM_198505	ATP13A5	ATPase type 13A5
chr11_-_62389376	0.028		B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chrX_-_6145887	0.028	NM_020742	NLGN4X	neuroligin 4, X-linked
chr1_+_67632168	0.028	NM_144701	IL23R	interleukin 23 receptor
chr2_-_74781061	0.028	NM_032603	LOXL3	lysyl oxidase-like 3
chr12_-_16758312	0.027	NM_001243611	LMO3	LIM domain only 3 (rhombotin-like 2)
chr8_-_101965601	0.026	NM_003406	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr3_-_149470230	0.026		COMMD2	COMM domain containing 2
chr3_-_71179736	0.025		FOXP1	forkhead box P1
chr4_+_15376174	0.025	NM_001135171	C1QTNF7	C1q and tumor necrosis factor related protein 7
chr3_+_121796695	0.025	NM_006889 NM_176892	CD86	CD86 molecule
chr1_-_21415672	0.024		EIF4G3	eukaryotic translation initiation factor 4 gamma, 3
chr4_+_71263598	0.024	NM_021225	PROL1	proline rich, lacrimal 1
chr9_+_132897342	0.024		GPR107	G protein-coupled receptor 107
chr6_-_43543600	0.024		XPO5	exportin 5
chr9_-_21385258	0.024	NM_000605	IFNA2	interferon, alpha 2
chr1_-_155210887	0.023		GBA	glucosidase, beta, acid
chr18_+_72342918	0.023	NM_001146189 NM_001146190 NM_017757	ZNF407	zinc finger protein 407
chr21_-_36252872	0.023		RUNX1	runt-related transcription factor 1
chrX_-_130964633	0.023		LOC286467	family with sequence similarity 195, member A pseudogene
chr9_-_8733893	0.023	NM_001040712 NM_001171025 NM_130391 NM_130392 NM_130393	PTPRD	protein tyrosine phosphatase, receptor type, D
chr10_-_74114865	0.023	NM_001002762 NM_017626	DNAJB12	DnaJ (Hsp40) homolog, subfamily B, member 12
chr7_-_38313232	0.022	NM_001003799 NM_001003806	TARP TRGV9	TCR gamma alternate reading frame protein T cell receptor gamma variable 9
chr1_-_8003224	0.022	NM_001561	TNFRSF9	tumor necrosis factor receptor superfamily, member 9
chr17_-_46667596	0.022		HOXB3	homeobox B3
chr11_+_68367824	0.022		PPP6R3	protein phosphatase 6, regulatory subunit 3
chr11_-_8964579	0.022	NM_020646	ASCL3	achaete-scute complex homolog 3 (Drosophila)
chr1_+_13516065	0.021	NM_001099852	PRAMEF20	PRAME family member 20
chr17_-_46799879	0.021	NM_032391	PRAC	prostate cancer susceptibility candidate
chr1_+_13736906	0.021	NM_001099852	PRAMEF20	PRAME family member 20
chr2_-_135782246	0.021	NM_001018046 NM_025052	YSK4	YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
chr3_+_63428752	0.021	NM_144642	SYNPR	synaptoporin
chr1_-_19578030	0.021		KIAA0090	KIAA0090
chr1_+_152758752	0.021	NM_178353	LCE1E	late cornified envelope 1E
chr8_+_123794043	0.021		ZHX2	zinc fingers and homeoboxes 2
chr10_+_32856650	0.020	NM_024688	C10orf68	chromosome 10 open reading frame 68
chr1_-_155211049	0.020	NM_001171812 NM_000157	GBA	glucosidase, beta, acid
chr20_-_44207964	0.020	NM_130896 NM_181510	WFDC8	WAP four-disulfide core domain 8
chr3_-_69037498	0.020		C3orf64	chromosome 3 open reading frame 64
chr17_-_41739261	0.020	NM_001040002	MEOX1	mesenchyme homeobox 1
chrX_-_101112548	0.020	NM_032946	NXF5	nuclear RNA export factor 5
chrM_+_11427	0.020
chr1_-_152297678	0.019	NM_002016	FLG	filaggrin
chrX_-_105282714	0.019	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr1_+_40713572	0.019	NM_001008740	TMCO2	transmembrane and coiled-coil domains 2
chr5_-_35118223	0.019	NM_001204314 NM_001204315 NM_001204316 NM_001204317 NM_001204318	PRLR	prolactin receptor
chr12_-_109027615	0.018		SELPLG	selectin P ligand
chr9_+_4792974	0.018		RCL1	RNA terminal phosphate cyclase-like 1
chr13_+_52436116	0.018	NM_031290	CCDC70	coiled-coil domain containing 70
chr8_+_123793988	0.018		ZHX2	zinc fingers and homeoboxes 2
chr6_-_137540435	0.018		IFNGR1	interferon gamma receptor 1
chrX_-_43832920	0.018	NM_000266	NDP	Norrie disease (pseudoglioma)
chr1_-_155774769	0.018		GON4L	gon-4-like (C. elegans)
chr1_-_7913490	0.017	NM_021995	UTS2	urotensin 2
chr3_-_119963141	0.017	NM_001168271 NM_153002	GPR156	G protein-coupled receptor 156
chr1_-_170038055	0.016	NM_001204517	KIFAP3	kinesin-associated protein 3
chrX_-_77582979	0.016	NM_006639	CYSLTR1	cysteinyl leukotriene receptor 1
chr6_-_137540504	0.016		IFNGR1	interferon gamma receptor 1
chr12_+_50024326	0.016	NM_001031698	PRPF40B	PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr3_-_42452022	0.016	NM_144634	LYZL4	lysozyme-like 4
chr6_-_46889620	0.016	NM_001098518	GPR116	G protein-coupled receptor 116
chr7_+_64126481	0.015	NM_001013746 NM_016220	ZNF107	zinc finger protein 107
chr6_-_138539626	0.015	NM_021635	PBOV1	prostate and breast cancer overexpressed 1
chr17_-_79838899	0.015
chr16_+_69958900	0.015	NM_199424	WWP2	WW domain containing E3 ubiquitin protein ligase 2
chr20_+_33759773	0.015	NM_006404	PROCR	protein C receptor, endothelial
chr1_-_169555624	0.015		F5	coagulation factor V (proaccelerin, labile factor)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
30.27	5.76e-03	GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.72	2.22e-02	GO:0005576	extracellular region

Nothing significant found in function category.