Motif ID: JUN.p2

Z-value: 0.880


Transcription factors associated with JUN.p2:

Gene SymbolEntrez IDGene Name
JUN 3725 jun oncogene
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
JUNDchr19_-_183924130.821.3e-02Click!
JUNBchr19_+_129022950.611.1e-01Click!
JUNchr1_-_592482870.216.1e-01Click!


Activity profile for motif JUN.p2.

activity profile for motif JUN.p2


Sorted Z-values histogram for motif JUN.p2

Sorted Z-values for motif JUN.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of JUN.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_33146500 1.440 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr5_-_172198160 1.001 NM_004417
DUSP1
dual specificity phosphatase 1
chr19_+_36024313 0.979 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr6_+_139456240 0.722 NM_016217
HECA
headcase homolog (Drosophila)
chr10_-_64576123 0.716 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr10_-_64576074 0.702 EGR2
early growth response 2
chr14_+_88851987 0.641 NM_001040428
NM_018418
SPATA7

spermatogenesis associated 7

chr14_+_101292483 0.633


chr2_+_220144024 0.598 NM_001039550
NM_006736
DNAJB2

DnaJ (Hsp40) homolog, subfamily B, member 2

chr2_-_224467049 0.598 SCG2
secretogranin II
chr15_+_76629101 0.592 NM_145805
ISL2
ISL LIM homeobox 2
chr14_+_88852065 0.579 SPATA7
spermatogenesis associated 7
chr2_-_224467095 0.571 SCG2
secretogranin II
chr20_+_33292117 0.568 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr21_-_45079327 0.550 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chr2_-_224467142 0.540 NM_003469
SCG2
secretogranin II
chr6_-_46293404 0.532 RCAN2
regulator of calcineurin 2
chr11_-_111782447 0.528 NM_001885
CRYAB
crystallin, alpha B
chr3_-_187463474 0.514 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr5_-_178054072 0.486 CLK4
CDC-like kinase 4
chr1_+_203274646 0.472 NM_006763
BTG2
BTG family, member 2
chr3_+_8543508 0.466 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr10_+_99079017 0.461 NM_005479
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr11_-_63381907 0.459 NM_007069
PLA2G16
phospholipase A2, group XVI
chr7_-_129592794 0.452 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H

chr11_-_63381840 0.451 PLA2G16
phospholipase A2, group XVI
chr6_-_46293628 0.450 NM_005822
RCAN2
regulator of calcineurin 2
chr14_+_101292451 0.440 MEG3
maternally expressed 3 (non-protein coding)
chr11_+_117070039 0.439 NM_001001522
NM_003186
TAGLN

transgelin

chr1_-_1293907 0.434 NM_032348
MXRA8
matrix-remodelling associated 8
chr6_+_39760138 0.430


chr8_-_108510094 0.428 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr7_-_129592711 0.427 NM_001202498
UBE2H
ubiquitin-conjugating enzyme E2H
chr12_-_50790391 0.422 NM_001145475
FAM186A
family with sequence similarity 186, member A
chr1_-_150602047 0.418 ENSA
endosulfine alpha
chr1_+_70820485 0.417 NM_001031693
NM_001036645
NM_001036646
HHLA3


HERV-H LTR-associating 3


chr20_+_17207669 0.412 PCSK2
proprotein convertase subtilisin/kexin type 2
chr11_-_35547144 0.402 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr6_+_136172802 0.400 NM_018945
PDE7B
phosphodiesterase 7B
chr11_-_63381940 0.399 NM_001128203
PLA2G16
phospholipase A2, group XVI
chr16_-_4588738 0.398 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr12_+_71833518 0.393 LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr10_+_35484829 0.391 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr5_-_178054001 0.385 NM_020666
CLK4
CDC-like kinase 4
chr21_+_47545189 0.385 COL6A2
collagen, type VI, alpha 2
chr4_+_108911008 0.373 HADH
hydroxyacyl-CoA dehydrogenase
chr20_-_34025955 0.372 NM_000557
GDF5
growth differentiation factor 5
chr8_+_26240522 0.367 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr3_+_101292987 0.366 PCNP
PEST proteolytic signal containing nuclear protein
chr12_+_10365415 0.363 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr7_+_28448970 0.359 LOC401317
uncharacterized LOC401317
chr3_-_187463227 0.358 BCL6
B-cell CLL/lymphoma 6
chr20_+_17207680 0.355 PCSK2
proprotein convertase subtilisin/kexin type 2
chrX_+_86772714 0.353 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr19_+_10527448 0.350 NM_001243121
PDE4A
phosphodiesterase 4A, cAMP-specific
chr12_-_92539614 0.349 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr2_+_28615695 0.348 FOSL2
FOS-like antigen 2
chr4_+_145567147 0.347 NM_022475
HHIP
hedgehog interacting protein
chr7_+_100199881 0.346 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr5_-_168727715 0.345 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr3_+_101293026 0.343 NM_020357
PCNP
PEST proteolytic signal containing nuclear protein
chr6_+_89791510 0.335 PNRC1
proline-rich nuclear receptor coactivator 1
chr6_+_56819706 0.333 NM_152731
BEND6
BEN domain containing 6
chr2_+_30454396 0.333 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr3_-_99594915 0.331 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr21_+_47545896 0.330 COL6A2
collagen, type VI, alpha 2
chr19_+_16187315 0.327 TPM4
tropomyosin 4
chr3_-_9811623 0.322 CAMK1
calcium/calmodulin-dependent protein kinase I
chr16_+_30996462 0.320 NM_001142777
NM_001142778
NM_025193
HSD3B7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr3_-_9811628 0.320 NM_003656
CAMK1
calcium/calmodulin-dependent protein kinase I
chr12_-_4754275 0.315 NM_006422
AKAP3
A kinase (PRKA) anchor protein 3
chr3_-_9811583 0.314 CAMK1
calcium/calmodulin-dependent protein kinase I
chr7_+_30174343 0.314 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr17_+_4046941 0.313 CYB5D2
cytochrome b5 domain containing 2
chr19_-_59066458 0.311 CHMP2A
charged multivesicular body protein 2A
chr16_-_79634610 0.310 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr11_-_6633400 0.310 TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr9_+_132251403 0.309 LOC100506190
uncharacterized LOC100506190
chr3_+_8543539 0.308 LMCD1
LIM and cysteine-rich domains 1
chr7_-_6388408 0.303 NM_001037163
C7orf70
chromosome 7 open reading frame 70
chr19_-_59066477 0.299 NM_014453
CHMP2A
charged multivesicular body protein 2A
chr4_-_142054431 0.299 NM_020724
RNF150
ring finger protein 150
chrX_+_153672449 0.295 NM_004699
FAM50A
family with sequence similarity 50, member A
chr19_+_16187266 0.291 TPM4
tropomyosin 4
chr9_-_99382073 0.291 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr3_+_69985750 0.288 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr9_+_17578952 0.288 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr12_-_6772252 0.287 NM_001127582
NM_001127583
NM_001127584
NM_001127585
NM_001127586
NM_016162
ING4





inhibitor of growth family, member 4





chr2_+_33172368 0.285 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr19_+_16187306 0.284 TPM4
tropomyosin 4
chr2_-_238322770 0.282 COL6A3
collagen, type VI, alpha 3
chr3_+_9975513 0.282 NM_015513
NM_001031717
NM_001077415
CRELD1


cysteine-rich with EGF-like domains 1


chr2_+_74153987 0.280 DGUOK
deoxyguanosine kinase
chr9_-_140353785 0.279 NM_001130969
NM_001130970
NM_001130971
NM_001178064
NM_015537
NELF




nasal embryonic LHRH factor




chr12_+_27397077 0.279 NM_015000
STK38L
serine/threonine kinase 38 like
chr2_+_152214105 0.278 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr2_+_105954008 0.278 NM_024093
C2orf49
chromosome 2 open reading frame 49
chr9_+_34990266 0.277 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr1_-_23886284 0.277 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr5_-_147286064 0.276 NM_206966
C5orf46
chromosome 5 open reading frame 46
chr2_-_238322840 0.275 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr12_+_71833761 0.272 NM_003667
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr1_+_228327966 0.271 GUK1
guanylate kinase 1
chrX_+_153672490 0.269 FAM50A
family with sequence similarity 50, member A
chr9_-_140353748 0.269 NELF
nasal embryonic LHRH factor
chr1_+_228327982 0.267 GUK1
guanylate kinase 1
chr19_-_59066353 0.266 NM_198426
CHMP2A
charged multivesicular body protein 2A
chr2_+_74154015 0.265 DGUOK
deoxyguanosine kinase
chr5_+_71403040 0.265 NM_005909
MAP1B
microtubule-associated protein 1B
chr1_+_183774214 0.264 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr4_+_668250 0.263 MYL5
myosin, light chain 5, regulatory
chr11_-_111749810 0.262 FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr10_+_35484054 0.261 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr22_+_35695792 0.259 NM_001135730
NM_001135732
NM_005488
TOM1


target of myb1 (chicken)


chr4_+_668312 0.258 MYL5
myosin, light chain 5, regulatory
chr19_-_18392048 0.258 JUND
jun D proto-oncogene
chr7_+_140396463 0.256 NM_004546
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr2_+_74153931 0.256 NM_080916
NM_080918
DGUOK

deoxyguanosine kinase

chr1_+_228328003 0.256 GUK1
guanylate kinase 1
chr12_+_133707212 0.253 NM_015394
ZNF10
zinc finger protein 10
chr4_-_8430185 0.252 ACOX3
acyl-CoA oxidase 3, pristanoyl
chr1_+_228328015 0.251 GUK1
guanylate kinase 1
chr14_+_60712469 0.250 NM_177952
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr11_+_12695851 0.250 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr1_-_150602020 0.248 ENSA
endosulfine alpha
chr20_+_42219558 0.248 NM_016004
IFT52
intraflagellar transport 52 homolog (Chlamydomonas)
chr17_-_40540576 0.247 STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr19_-_59066303 0.247 CHMP2A
charged multivesicular body protein 2A
chrX_+_110339374 0.245 NM_002578
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr6_+_56819923 0.244 BEND6
BEN domain containing 6
chr17_-_7835146 0.244 NM_021210
NM_001166621
TRAPPC1

trafficking protein particle complex 1

chr7_+_127228405 0.242 NM_001662
ARF5
ADP-ribosylation factor 5
chr17_+_58677489 0.240 NM_003620
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr19_-_18392436 0.239 JUND
jun D proto-oncogene
chr9_-_73029539 0.237 NM_001206
KLF9
Kruppel-like factor 9
chr22_+_35695872 0.236 TOM1
target of myb1 (chicken)
chr2_+_74781846 0.235 DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr4_+_108911042 0.233 HADH
hydroxyacyl-CoA dehydrogenase
chr6_+_30524485 0.231 NM_001077497
NM_025263
PRR3

proline rich 3

chr16_-_4588379 0.229 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr10_-_62703822 0.227 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr1_+_85527992 0.227 NM_145172
WDR63
WD repeat domain 63
chr6_+_35227234 0.225 ZNF76
zinc finger protein 76
chr19_-_59066372 0.225 CHMP2A
charged multivesicular body protein 2A
chr19_-_51014344 0.225 NM_138334
JOSD2
Josephin domain containing 2
chr2_+_74781511 0.225 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr15_-_66790068 0.223 NM_006049
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr17_+_58677603 0.223 PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr19_-_18392413 0.222 NM_005354
JUND
jun D proto-oncogene
chr11_-_63381485 0.222 PLA2G16
phospholipase A2, group XVI
chr15_-_82338459 0.221 MEX3B
mex-3 homolog B (C. elegans)
chr19_-_48018163 0.221 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr3_-_141944441 0.220 NM_001039547
GK5
glycerol kinase 5 (putative)
chr2_-_211168315 0.220 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chrX_-_13956644 0.220 NM_001001994
GPM6B
glycoprotein M6B
chr7_-_105516923 0.219 NM_020725
NM_152749
ATXN7L1

ataxin 7-like 1

chr1_-_76397975 0.219 NM_080868
ASB17
ankyrin repeat and SOCS box containing 17
chr17_-_26662439 0.219 NM_174887
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chr22_+_24236575 0.218


chr1_-_150602089 0.218 NM_004436
NM_207042
NM_207043
NM_207044
NM_207168
ENSA




endosulfine alpha




chr12_-_102455793 0.217 NM_016053
CCDC53
coiled-coil domain containing 53
chr6_-_34664587 0.216 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr3_-_107941168 0.213 NM_018010
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr1_-_150849211 0.212 NM_001197325
NM_001668
NM_178427
ARNT


aryl hydrocarbon receptor nuclear translocator


chr16_+_29912146 0.212 NM_181718
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr6_+_39760148 0.212 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr9_+_97521930 0.212 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr2_-_238322815 0.208 COL6A3
collagen, type VI, alpha 3
chr16_+_475629 0.207 NM_014700
RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr19_+_57831824 0.207 NM_213598
ZNF543
zinc finger protein 543
chr19_-_46088074 0.205 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr11_+_113930296 0.205 ZBTB16
zinc finger and BTB domain containing 16
chr22_+_24236556 0.204 NM_002415
MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr16_+_29973341 0.204 NM_001083613
NM_194280
TMEM219

transmembrane protein 219

chr1_-_23885916 0.203 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr9_+_34989637 0.201 NM_001135004
NM_012266
DNAJB5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr14_+_105219466 0.199 NM_006427
NM_021709
SIVA1

SIVA1, apoptosis-inducing factor

chr15_-_80216004 0.199 ST20
suppressor of tumorigenicity 20
chr1_-_713985 0.198 LOC100288069
general transcription factor IIi pseudogene
chrX_+_43514157 0.198 MAOA
monoamine oxidase A
chr1_-_110933635 0.198 SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr11_+_18343794 0.197 NM_001142307
NM_005316
GTF2H1

general transcription factor IIH, polypeptide 1, 62kDa

chr12_-_102455763 0.197 CCDC53
coiled-coil domain containing 53
chr22_+_24236569 0.196 MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr1_+_201476283 0.196


chr16_+_31119730 0.196 BCKDK
branched chain ketoacid dehydrogenase kinase
chr14_-_77494974 0.196 NM_024496
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr15_+_44084493 0.195 SERF2
small EDRK-rich factor 2
chr15_+_31619043 0.195 NM_015995
KLF13
Kruppel-like factor 13
chr5_+_32711437 0.193 NM_000908
NM_001204375
NPR3

natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)

chr11_+_6226797 0.193 NM_173525
C11orf42
chromosome 11 open reading frame 42
chr16_+_31119748 0.193 BCKDK
branched chain ketoacid dehydrogenase kinase
chr12_-_102455739 0.193 CCDC53
coiled-coil domain containing 53
chr16_+_475605 0.192 RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr3_+_187871473 0.192 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr13_+_49822046 0.192 NM_001193478
NM_030911
CDADC1

cytidine and dCMP deaminase domain containing 1

chr21_+_47546427 0.192 COL6A2
collagen, type VI, alpha 2
chr12_+_107168336 0.190 NM_018157
RIC8B
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr1_-_150601911 0.190 ENSA
endosulfine alpha
chr3_+_184053682 0.190 NM_001171093
FAM131A
family with sequence similarity 131, member A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.22 1.41e-02 GO:0044260 cellular macromolecule metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 6.22e-09 GO:0005622 intracellular
1.13 9.77e-09 GO:0044424 intracellular part
1.26 1.44e-07 GO:0005634 nucleus
1.15 2.53e-07 GO:0043229 intracellular organelle
1.15 3.89e-07 GO:0043226 organelle
1.15 7.24e-06 GO:0043231 intracellular membrane-bounded organelle
1.15 9.04e-06 GO:0043227 membrane-bounded organelle
1.15 1.40e-04 GO:0005737 cytoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 1.75e-06 GO:0005488 binding
1.19 2.07e-06 GO:0005515 protein binding
1.23 3.42e-02 GO:0003676 nucleic acid binding