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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: KLF4.p3

Z-value: 0.409

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_33285493	0.392	NM_005453	ZBTB22	zinc finger and BTB domain containing 22
chr6_-_33285718	0.346	NM_001145338	ZBTB22	zinc finger and BTB domain containing 22
chr18_+_11981552	0.308		IMPA2	inositol(myo)-1(or 4)-monophosphatase 2
chr9_+_130922471	0.306	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr2_+_30369868	0.300		YPEL5	yippee-like 5 (Drosophila)
chrY_-_1521733	0.297	NM_001173474 NM_004192	ASMTL	acetylserotonin O-methyltransferase-like
chrY_-_1522648	0.289	NM_001173473	ASMTL	acetylserotonin O-methyltransferase-like
chrX_-_1572648	0.286	NM_001173473	ASMTL	acetylserotonin O-methyltransferase-like
chrX_-_1571733	0.273	NM_001173474 NM_004192	ASMTL	acetylserotonin O-methyltransferase-like
chr18_+_11981421	0.266	NM_014214	IMPA2	inositol(myo)-1(or 4)-monophosphatase 2
chr1_-_11714738	0.252	NM_012168	FBXO2	F-box protein 2
chr18_+_11981457	0.243		IMPA2	inositol(myo)-1(or 4)-monophosphatase 2
chr19_+_8455265	0.239		RAB11B	RAB11B, member RAS oncogene family
chr14_-_99947080	0.233		SETD3	SET domain containing 3
chr16_+_3074027	0.231	NM_001142350 NM_024339	THOC6	THO complex 6 homolog (Drosophila)
chr1_-_1850704	0.230	NM_178545	TMEM52	transmembrane protein 52
chr2_+_30369800	0.227		YPEL5	yippee-like 5 (Drosophila)
chr19_+_8455243	0.224		RAB11B	RAB11B, member RAS oncogene family
chrX_-_134232663	0.208		LINC00087	long intergenic non-protein coding RNA 87
chr19_+_33166312	0.205	NM_207391	RGS9BP	regulator of G protein signaling 9 binding protein
chr2_+_24272583	0.204	NM_004116 NM_054033	FKBP1B	FK506 binding protein 1B, 12.6 kDa
chr9_-_139890984	0.203	NM_004669	CLIC3	chloride intracellular channel 3
chr15_+_72410630	0.203	NM_001172111 NM_145204	SENP8	SUMO/sentrin specific peptidase family member 8
chr22_+_45098091	0.200	NM_181334	PRR5-ARHGAP8 PRR5	PRR5-ARHGAP8 readthrough proline rich 5 (renal)
chr17_-_66453561	0.200	NM_017983	WIPI1	WD repeat domain, phosphoinositide interacting 1
chr15_+_72410724	0.199		SENP8	SUMO/sentrin specific peptidase family member 8
chr8_+_144816287	0.193		LOC100128338	uncharacterized LOC100128338
chr10_+_134351272	0.192	NM_005539	INPP5A	inositol polyphosphate-5-phosphatase, 40kDa
chr19_-_38746978	0.191		PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr9_+_139685760	0.190	NM_032928	TMEM141	transmembrane protein 141
chr17_-_72869068	0.190	NM_004110 NM_024417	FDXR	ferredoxin reductase
chr14_-_21566497	0.189		ZNF219	zinc finger protein 219
chr14_+_105941061	0.189	NM_001312	CRIP2	cysteine-rich protein 2
chr20_+_62371218	0.187		SLC2A4RG	SLC2A4 regulator
chr19_-_50143350	0.186	NM_006270	RRAS	related RAS viral (r-ras) oncogene homolog
chr17_-_7307413	0.183	NM_152766	C17orf61-PLSCR3 C17orf61	C17orf61-PLSCR3 readthrough chromosome 17 open reading frame 61
chr11_+_64001974	0.181	NM_001243733 NM_003377	VEGFB	vascular endothelial growth factor B
chr7_+_97911023	0.180		BRI3	brain protein I3
chr8_-_99837768	0.179	NM_006281	STK3	serine/threonine kinase 3
chr17_+_79989485	0.178	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr7_+_73498149	0.178		LIMK1	LIM domain kinase 1
chr16_+_3074060	0.177		THOC6	THO complex 6 homolog (Drosophila)
chr16_+_3074051	0.176		THOC6	THO complex 6 homolog (Drosophila)
chr2_+_24272627	0.171		FKBP1B	FK506 binding protein 1B, 12.6 kDa
chr2_+_30369749	0.165	NM_001127399 NM_001127400 NM_001127401 NM_016061	YPEL5	yippee-like 5 (Drosophila)
chr4_-_71705613	0.164	NM_002092	GRSF1	G-rich RNA sequence binding factor 1
chr11_-_575848	0.164		LOC143666	uncharacterized LOC143666
chr20_+_33464327	0.163	NM_001076552 NM_018677	ACSS2	acyl-CoA synthetase short-chain family member 2
chr19_+_8478181	0.162	NM_001005415 NM_001005416 NM_016496	MARCH2	membrane-associated ring finger (C3HC4) 2
chr10_+_111985628	0.160	NM_005962	MXI1	MAX interactor 1
chr19_-_47734215	0.157	NM_014417	BBC3	BCL2 binding component 3
chr14_-_21493122	0.154	NM_201538 NM_201539 NM_201540 NM_201541	NDRG2	NDRG family member 2
chr16_+_1203240	0.154	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr20_+_33464404	0.154		ACSS2	acyl-CoA synthetase short-chain family member 2
chr1_-_173446273	0.151		LOC100506023	uncharacterized LOC100506023
chr14_-_21566728	0.150	NM_016423	ZNF219	zinc finger protein 219
chr19_+_35629727	0.150	NM_021902	FXYD1	FXYD domain containing ion transport regulator 1
chr12_+_50017340	0.146	NM_012272	PRPF40B	PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr17_-_42201009	0.146	NM_001015053 NM_005474	HDAC5	histone deacetylase 5
chr7_+_100797685	0.145	NM_001283	AP1S1	adaptor-related protein complex 1, sigma 1 subunit
chr1_+_211432726	0.145		RCOR3	REST corepressor 3
chr12_+_111843743	0.143	NM_005475	SH2B3	SH2B adaptor protein 3
chr7_+_21468293	0.142
chr20_+_62371109	0.141	NM_020062	SLC2A4RG	SLC2A4 regulator
chr10_-_103543156	0.139	NM_006993	NPM3	nucleophosmin/nucleoplasmin 3
chr8_+_124428964	0.139	NM_018024	WDYHV1	WDYHV motif containing 1
chr11_+_71498497	0.136	NM_001099653 NM_018172 NM_152563	FAM86C1	family with sequence similarity 86, member C1
chr10_+_23728197	0.136	NM_001145373	OTUD1	OTU domain containing 1
chr9_+_140500148	0.135		ARRDC1	arrestin domain containing 1
chr16_-_3074225	0.134	NM_001002017 NM_001002018 NM_017885	HCFC1R1	host cell factor C1 regulator 1 (XPO1 dependent)
chr6_-_31697568	0.134		DDAH2	dimethylarginine dimethylaminohydrolase 2
chrX_-_3631654	0.133	NM_005044	PRKX	protein kinase, X-linked
chr19_-_8455552	0.133		LOC100507567	uncharacterized LOC100507567
chr17_+_55333843	0.132	NM_138962	MSI2	musashi homolog 2 (Drosophila)
chr9_+_133971902	0.132		AIF1L	allograft inflammatory factor 1-like
chr20_-_61492945	0.132	NM_006602	TCFL5	transcription factor-like 5 (basic helix-loop-helix)
chr11_-_66234176	0.132		MRPL11	mitochondrial ribosomal protein L11
chr8_-_144650998	0.131		C8orf73	chromosome 8 open reading frame 73
chr16_+_3074041	0.130		THOC6	THO complex 6 homolog (Drosophila)
chr19_-_40950238	0.130	NM_203344	SERTAD3	SERTA domain containing 3
chr19_-_38747171	0.129	NM_001243947 NM_033256	PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr11_-_65686439	0.129	NM_001135635 NM_031450	C11orf68	chromosome 11 open reading frame 68
chr7_+_73498106	0.129	NM_002314	LIMK1	LIM domain kinase 1
chr9_+_133971862	0.128	NM_001185095 NM_001185096 NM_031426	AIF1L	allograft inflammatory factor 1-like
chr15_+_80445177	0.127	NM_000137	FAH	fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr19_+_47104389	0.126		CALM3	calmodulin 3 (phosphorylase kinase, delta)
chr17_-_62207362	0.126		ERN1	endoplasmic reticulum to nucleus signaling 1
chr6_-_34664517	0.126		C6orf106	chromosome 6 open reading frame 106
chr1_-_113257873	0.126	NM_005167	PPM1J	protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr8_-_103251002	0.125	NM_001172477 NM_001172478 NM_015713	RRM2B	ribonucleotide reductase M2 B (TP53 inducible)
chr1_-_209979388	0.123	NM_001206696 NM_006147	IRF6	interferon regulatory factor 6
chr19_-_40971623	0.122	NM_000713	BLVRB	biliverdin reductase B (flavin reductase (NADPH))
chr14_+_96342728	0.122		LOC100507043	uncharacterized LOC100507043
chr17_-_26903854	0.122		ALDOC	aldolase C, fructose-bisphosphate
chr6_-_31698033	0.122	NM_013974	DDAH2	dimethylarginine dimethylaminohydrolase 2
chr10_+_92980322	0.121	NM_032373	PCGF5	polycomb group ring finger 5
chr7_+_100209941	0.121	NM_001040098 NM_001040099 NM_023948	MOSPD3	motile sperm domain containing 3
chr1_-_161102367	0.121		DEDD	death effector domain containing
chr19_+_8455200	0.120	NM_004218	RAB11B	RAB11B, member RAS oncogene family
chr8_-_127570465	0.120		FAM84B	family with sequence similarity 84, member B
chr8_-_145638929	0.119		SLC39A4	solute carrier family 39 (zinc transporter), member 4
chr17_-_26903926	0.119	NM_005165	ALDOC	aldolase C, fructose-bisphosphate
chr14_+_77648082	0.119	NM_020431	TMEM63C	transmembrane protein 63C
chr6_-_4135701	0.118	NM_001166010 NM_006117 NM_206836	ECI2	enoyl-CoA delta isomerase 2
chr22_+_45098046	0.118	NM_181333	PRR5	proline rich 5 (renal)
chr17_+_75277491	0.118	NM_001113491	SEPT9	septin 9
chr7_+_97910978	0.117	NM_001159491 NM_015379	BRI3	brain protein I3
chr22_+_46546498	0.117	NM_001001928 NM_005036	PPARA	peroxisome proliferator-activated receptor alpha
chr17_+_66244220	0.114
chr18_+_596997	0.114	NM_014410	CLUL1	clusterin-like 1 (retinal)
chr3_-_52001388	0.114	NM_020418 NM_001174100 NM_033008	PCBP4	poly(rC) binding protein 4
chr17_-_62971505	0.114		AMZ2P1	archaelysin family metallopeptidase 2 pseudogene 1
chr1_-_231175971	0.114	NM_198552	FAM89A	family with sequence similarity 89, member A
chr22_+_51113069	0.113	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr7_-_75368276	0.113	NM_001243198 NM_005338	HIP1	huntingtin interacting protein 1
chr4_+_1795004	0.113	NM_000142 NM_001163213 NM_022965	FGFR3	fibroblast growth factor receptor 3
chr8_-_12051533	0.113	NM_001083537	FAM86B2 FAM86B1	family with sequence similarity 86, member B2 family with sequence similarity 86, member B1
chr9_+_140500097	0.112		ARRDC1	arrestin domain containing 1
chr17_-_26879645	0.112	NM_005148 NM_054035	UNC119	unc-119 homolog (C. elegans)
chr19_+_41284161	0.111		RAB4B-EGLN2 RAB4B	RAB4B-EGLN2 readthrough RAB4B, member RAS oncogene family
chr1_-_11714396	0.111		FBXO2	F-box protein 2
chr6_-_31697953	0.111		DDAH2	dimethylarginine dimethylaminohydrolase 2
chr19_+_17858504	0.111	NM_001161357 NM_001161358	FCHO1	FCH domain only 1
chr6_+_37137882	0.111	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr11_-_207403	0.110	NM_001098787 NM_016526	BET1L	blocked early in transport 1 homolog (S. cerevisiae)-like
chr10_+_72163860	0.110	NM_004096	EIF4EBP2	eukaryotic translation initiation factor 4E binding protein 2
chr1_+_150980895	0.110	NM_021222	PRUNE	prune homolog (Drosophila)
chr17_-_26879577	0.110		UNC119	unc-119 homolog (C. elegans)
chr1_-_161102210	0.110	NM_001039712	DEDD	death effector domain containing
chr7_+_21467572	0.109	NM_003112	SP4	Sp4 transcription factor
chr11_+_107799134	0.109	NM_017516	RAB39A	RAB39A, member RAS oncogene family
chr19_-_40950200	0.109		SERTAD3	SERTA domain containing 3
chr19_-_55972935	0.109		ISOC2	isochorismatase domain containing 2
chr3_+_142895132	0.109
chr11_-_64052164	0.109	NM_004322 NM_032989	BAD	BCL2-associated agonist of cell death
chr1_+_211432732	0.108		RCOR3	REST corepressor 3
chr12_+_57482886	0.108		NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr11_-_77899640	0.108	NM_001029859	KCTD21	potassium channel tetramerisation domain containing 21
chr11_+_65292526	0.108	NM_001048218 NM_020680	SCYL1	SCY1-like 1 (S. cerevisiae)
chr17_-_42200957	0.108		HDAC5	histone deacetylase 5
chr5_+_10564431	0.107	NM_001164440	ANKRD33B	ankyrin repeat domain 33B
chr19_-_44143943	0.107	NM_145296	CADM4	cell adhesion molecule 4
chr18_-_77793914	0.107
chr11_-_64052123	0.106		BAD	BCL2-associated agonist of cell death
chr9_-_38069082	0.106		SHB	Src homology 2 domain containing adaptor protein B
chr16_-_8962842	0.106	NM_014316	CARHSP1	calcium regulated heat stable protein 1, 24kDa
chr17_-_43045612	0.105	NM_006688	C1QL1	complement component 1, q subcomponent-like 1
chr12_+_118814310	0.105	NM_022491	SUDS3	suppressor of defective silencing 3 homolog (S. cerevisiae)
chr10_+_49514652	0.105		MAPK8	mitogen-activated protein kinase 8
chr2_+_23608297	0.105	NM_052920	KLHL29	kelch-like 29 (Drosophila)
chr1_-_11714471	0.104		FBXO2	F-box protein 2
chr17_-_882905	0.104	NM_022463	NXN	nucleoredoxin
chr12_+_58148775	0.104	NM_138396	MARCH9	membrane-associated ring finger (C3HC4) 9
chr19_-_58858900	0.104		A1BG	alpha-1-B glycoprotein
chr22_-_19166296	0.103	NM_005984	SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr2_+_24299751	0.102		LOC375190	UPF0638 protein B
chr9_+_140500054	0.102	NM_152285	ARRDC1	arrestin domain containing 1
chr9_+_140500136	0.102		ARRDC1	arrestin domain containing 1
chr2_-_179315756	0.101	NM_003690	PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator
chrX_+_153237990	0.101	NM_003492	TMEM187	transmembrane protein 187
chr9_+_77703412	0.101		OSTF1	osteoclast stimulating factor 1
chr1_-_15850718	0.101		CASP9	caspase 9, apoptosis-related cysteine peptidase
chr13_+_28195961	0.101		POLR1D	polymerase (RNA) I polypeptide D, 16kDa
chr2_-_27294491	0.101	NM_001134693	OST4	oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr11_-_64570621	0.101	NM_004579	MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2
chr22_-_39190103	0.101		DNAL4	dynein, axonemal, light chain 4
chr20_+_44650260	0.100	NM_001134771	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr14_+_77648127	0.100		TMEM63C	transmembrane protein 63C
chr6_+_42981840	0.100	NM_057161	KLHDC3	kelch domain containing 3
chr17_-_31204071	0.099		MYO1D	myosin ID
chr19_+_47778099	0.099	NM_178511	PRR24	proline rich 24
chr6_-_30710219	0.099	NM_005803	FLOT1	flotillin 1
chr13_-_114018201	0.099		GRTP1	growth hormone regulated TBC protein 1
chr9_-_23821842	0.099	NM_001171195	ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chrX_-_48814758	0.099		OTUD5	OTU domain containing 5
chr17_-_42081836	0.098	NM_004160	PYY	peptide YY
chr9_+_139685816	0.098
chr12_+_6875686	0.098		PTMS	parathymosin
chr11_+_33279167	0.097	NM_001048200 NM_005734	HIPK3	homeodomain interacting protein kinase 3
chr11_+_47279467	0.097	NM_001130101 NM_005693	NR1H3	nuclear receptor subfamily 1, group H, member 3
chr2_+_42795844	0.097		MTA3	metastasis associated 1 family, member 3
chr12_+_6875468	0.097	NM_002824	PTMS	parathymosin
chr12_+_57482922	0.097		NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr10_+_112257624	0.097	NM_004419	DUSP5	dual specificity phosphatase 5
chr17_-_57184116	0.096		TRIM37	tripartite motif containing 37
chr17_+_21188021	0.096		MAP2K3	mitogen-activated protein kinase kinase 3
chr14_-_74551073	0.096		ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr3_+_127391768	0.096	NM_032548 NM_172027	ABTB1	ankyrin repeat and BTB (POZ) domain containing 1
chr19_-_46000159	0.096	NM_005619 NM_206900	RTN2	reticulon 2
chr6_-_31633587	0.095	NM_001199238 NM_001199239	GPANK1	G patch domain and ankyrin repeats 1
chr6_+_126070895	0.095		HEY2	hairy/enhancer-of-split related with YRPW motif 2
chr19_-_6110491	0.095		RFX2	regulatory factor X, 2 (influences HLA class II expression)
chrX_+_47077426	0.095	NM_033018	CDK16	cyclin-dependent kinase 16
chr17_+_75369372	0.095		SEPT9	septin 9
chr22_-_19166133	0.095		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr19_+_7985193	0.095	NM_003083	SNAPC2	small nuclear RNA activating complex, polypeptide 2, 45kDa
chr22_+_41347328	0.095	NM_014248	RBX1	ring-box 1, E3 ubiquitin protein ligase
chr1_-_9970265	0.094	NM_001012329 NM_020248	CTNNBIP1	catenin, beta interacting protein 1
chr19_+_47104559	0.094		CALM3	calmodulin 3 (phosphorylase kinase, delta)
chr6_+_42981955	0.093		KLHDC3	kelch domain containing 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.08	2.49e-25	GO:0009987	cellular process
1.14	1.06e-20	GO:0044237	cellular metabolic process
1.12	1.19e-17	GO:0008152	metabolic process
1.16	8.83e-17	GO:0044260	cellular macromolecule metabolic process
1.12	6.15e-16	GO:0044238	primary metabolic process
1.10	1.13e-15	GO:0065007	biological regulation
1.11	3.45e-15	GO:0050794	regulation of cellular process
1.10	1.14e-14	GO:0050789	regulation of biological process
1.14	2.41e-14	GO:0043170	macromolecule metabolic process
1.15	3.19e-11	GO:0031323	regulation of cellular metabolic process
1.22	1.77e-10	GO:0006464	protein modification process
1.14	1.86e-10	GO:0019222	regulation of metabolic process
1.18	7.99e-10	GO:0044267	cellular protein metabolic process
1.14	4.24e-09	GO:0080090	regulation of primary metabolic process
1.20	7.98e-09	GO:0043412	macromolecule modification
1.14	1.50e-08	GO:0060255	regulation of macromolecule metabolic process
1.44	4.59e-08	GO:0007264	small GTPase mediated signal transduction
1.14	7.32e-08	GO:0006807	nitrogen compound metabolic process
1.18	1.18e-07	GO:0048523	negative regulation of cellular process
1.22	1.63e-07	GO:0009966	regulation of signal transduction
1.15	2.12e-07	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14	2.86e-07	GO:0034641	cellular nitrogen compound metabolic process
1.20	4.22e-07	GO:0023051	regulation of signaling
1.14	5.44e-07	GO:0019538	protein metabolic process
1.22	7.86e-07	GO:0035556	intracellular signal transduction
1.22	1.70e-06	GO:0051641	cellular localization
1.25	1.78e-06	GO:0007049	cell cycle
1.16	1.97e-06	GO:0048519	negative regulation of biological process
1.27	2.73e-06	GO:0015031	protein transport
1.21	2.99e-06	GO:0009056	catabolic process
1.27	3.17e-06	GO:0045184	establishment of protein localization
1.19	4.17e-06	GO:0006996	organelle organization
1.21	7.66e-06	GO:0033036	macromolecule localization
1.23	8.16e-06	GO:0008104	protein localization
1.11	1.17e-05	GO:0051716	cellular response to stimulus
1.22	1.53e-05	GO:0044248	cellular catabolic process
1.26	1.67e-05	GO:0033554	cellular response to stress
1.22	1.80e-05	GO:0051649	establishment of localization in cell
1.23	2.09e-05	GO:0043067	regulation of programmed cell death
1.33	2.46e-05	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.33	2.56e-05	GO:0043068	positive regulation of programmed cell death
1.30	2.65e-05	GO:0051726	regulation of cell cycle
1.19	2.65e-05	GO:0065009	regulation of molecular function
1.23	2.72e-05	GO:0010941	regulation of cell death
1.23	5.09e-05	GO:0006793	phosphorus metabolic process
1.23	5.09e-05	GO:0006796	phosphate metabolic process
1.23	5.51e-05	GO:0042981	regulation of apoptosis
1.32	6.20e-05	GO:0043065	positive regulation of apoptosis
1.32	6.52e-05	GO:0010942	positive regulation of cell death
1.13	7.30e-05	GO:0051171	regulation of nitrogen compound metabolic process
1.22	7.52e-05	GO:0032268	regulation of cellular protein metabolic process
1.13	7.67e-05	GO:0071842	cellular component organization at cellular level
1.24	1.09e-04	GO:0008219	cell death
1.38	1.31e-04	GO:0012502	induction of programmed cell death
1.26	1.36e-04	GO:0006468	protein phosphorylation
1.11	1.37e-04	GO:0007165	signal transduction
1.25	1.51e-04	GO:0046907	intracellular transport
1.14	1.54e-04	GO:0048522	positive regulation of cellular process
1.13	1.60e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13	1.64e-04	GO:0048518	positive regulation of biological process
1.37	1.83e-04	GO:0006917	induction of apoptosis
1.66	2.12e-04	GO:0031098	stress-activated protein kinase signaling cascade
1.24	2.28e-04	GO:0016265	death
1.11	2.66e-04	GO:0016043	cellular component organization
1.21	2.94e-04	GO:0051246	regulation of protein metabolic process
1.20	5.18e-04	GO:0050790	regulation of catalytic activity
1.14	5.31e-04	GO:0090304	nucleic acid metabolic process
1.12	6.07e-04	GO:0071841	cellular component organization or biogenesis at cellular level
1.10	6.58e-04	GO:0023052	signaling
1.24	8.50e-04	GO:0031399	regulation of protein modification process
1.31	1.03e-03	GO:0045859	regulation of protein kinase activity
1.10	1.07e-03	GO:0071840	cellular component organization or biogenesis
1.11	1.10e-03	GO:0051234	establishment of localization
1.60	1.22e-03	GO:0007265	Ras protein signal transduction
1.39	1.24e-03	GO:0071900	regulation of protein serine/threonine kinase activity
1.16	1.37e-03	GO:0009059	macromolecule biosynthetic process
1.23	1.46e-03	GO:0022402	cell cycle process
1.16	1.48e-03	GO:0034645	cellular macromolecule biosynthetic process
1.24	1.75e-03	GO:0012501	programmed cell death
1.17	1.80e-03	GO:0007399	nervous system development
1.29	2.27e-03	GO:0051338	regulation of transferase activity
1.24	2.81e-03	GO:0019220	regulation of phosphate metabolic process
1.24	2.81e-03	GO:0051174	regulation of phosphorus metabolic process
1.25	3.25e-03	GO:0001932	regulation of protein phosphorylation
1.24	3.29e-03	GO:0006915	apoptosis
1.12	3.53e-03	GO:0010468	regulation of gene expression
1.40	3.83e-03	GO:0000165	MAPKKK cascade
1.20	4.08e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.32	4.29e-03	GO:0010627	regulation of intracellular protein kinase cascade
1.25	4.44e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.22	4.74e-03	GO:0016310	phosphorylation
1.28	5.17e-03	GO:0043549	regulation of kinase activity
1.11	5.31e-03	GO:0006810	transport
1.22	5.45e-03	GO:0051128	regulation of cellular component organization
1.20	5.91e-03	GO:0009892	negative regulation of metabolic process
1.49	5.92e-03	GO:0046039	GTP metabolic process
1.20	5.99e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.33	6.04e-03	GO:0051301	cell division
1.14	6.07e-03	GO:0048583	regulation of response to stimulus
1.24	6.29e-03	GO:0042325	regulation of phosphorylation
1.11	6.80e-03	GO:0031326	regulation of cellular biosynthetic process
1.12	7.52e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.50	9.07e-03	GO:0006184	GTP catabolic process
1.43	1.02e-02	GO:0043408	regulation of MAPKKK cascade
1.14	1.07e-02	GO:0010467	gene expression
1.32	1.13e-02	GO:0010564	regulation of cell cycle process
1.12	1.28e-02	GO:0044249	cellular biosynthetic process
1.51	1.38e-02	GO:0008286	insulin receptor signaling pathway
1.11	1.39e-02	GO:0009889	regulation of biosynthetic process
1.09	1.41e-02	GO:0051179	localization
1.24	1.49e-02	GO:0009057	macromolecule catabolic process
1.26	1.82e-02	GO:0044265	cellular macromolecule catabolic process
1.39	1.92e-02	GO:0071375	cellular response to peptide hormone stimulus
1.11	2.00e-02	GO:0010556	regulation of macromolecule biosynthetic process
1.33	2.29e-02	GO:0032870	cellular response to hormone stimulus
1.19	2.43e-02	GO:0031324	negative regulation of cellular metabolic process
1.30	2.44e-02	GO:0030163	protein catabolic process
1.65	2.92e-02	GO:0000209	protein polyubiquitination
1.65	2.92e-02	GO:0045787	positive regulation of cell cycle
1.64	3.10e-02	GO:0007254	JNK cascade
1.63	3.28e-02	GO:0008629	induction of apoptosis by intracellular signals
1.11	3.30e-02	GO:0009058	biosynthetic process
1.21	3.37e-02	GO:0016192	vesicle-mediated transport
1.42	3.38e-02	GO:0032869	cellular response to insulin stimulus
1.31	3.40e-02	GO:0071495	cellular response to endogenous stimulus
1.12	3.46e-02	GO:0051252	regulation of RNA metabolic process
1.30	3.57e-02	GO:0051056	regulation of small GTPase mediated signal transduction
1.21	4.54e-02	GO:0043085	positive regulation of catalytic activity
1.37	4.74e-02	GO:0032868	response to insulin stimulus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.11	1.81e-57	GO:0005622	intracellular
1.12	1.13e-55	GO:0044424	intracellular part
1.15	6.78e-42	GO:0005737	cytoplasm
1.12	2.27e-36	GO:0043226	organelle
1.11	6.88e-36	GO:0043229	intracellular organelle
1.12	7.35e-34	GO:0043227	membrane-bounded organelle
1.12	8.56e-34	GO:0043231	intracellular membrane-bounded organelle
1.16	5.68e-24	GO:0005634	nucleus
1.14	1.04e-22	GO:0044444	cytoplasmic part
1.26	1.90e-19	GO:0005829	cytosol
1.13	1.07e-15	GO:0044446	intracellular organelle part
1.12	2.11e-14	GO:0044422	organelle part
1.20	4.06e-12	GO:0044428	nuclear part
1.19	8.59e-11	GO:0070013	intracellular organelle lumen
1.18	2.60e-10	GO:0043233	organelle lumen
1.18	5.36e-10	GO:0031974	membrane-enclosed lumen
1.21	5.63e-10	GO:0031981	nuclear lumen
1.23	8.25e-09	GO:0005654	nucleoplasm
1.03	6.94e-07	GO:0005623	cell
1.03	8.30e-07	GO:0044464	cell part
1.12	2.31e-05	GO:0043234	protein complex
1.24	4.06e-04	GO:0015630	microtubule cytoskeleton
1.17	6.63e-04	GO:0005739	mitochondrion
1.95	6.92e-04	GO:0008287	protein serine/threonine phosphatase complex
1.11	9.77e-04	GO:0043228	non-membrane-bounded organelle
1.11	9.77e-04	GO:0043232	intracellular non-membrane-bounded organelle
1.09	1.22e-03	GO:0032991	macromolecular complex
1.44	1.49e-03	GO:0031252	cell leading edge

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.15	2.12e-36	GO:0005515	protein binding
1.09	1.51e-34	GO:0005488	binding
1.19	1.26e-10	GO:0000166	nucleotide binding
1.21	1.51e-10	GO:0035639	purine ribonucleoside triphosphate binding
1.21	2.26e-10	GO:0017076	purine nucleotide binding
1.21	2.86e-10	GO:0032553	ribonucleotide binding
1.21	2.86e-10	GO:0032555	purine ribonucleotide binding
1.11	1.74e-09	GO:0003824	catalytic activity
1.32	7.94e-09	GO:0019899	enzyme binding
1.19	7.45e-07	GO:0030554	adenyl nucleotide binding
1.19	1.02e-06	GO:0005524	ATP binding
1.19	1.25e-06	GO:0032559	adenyl ribonucleotide binding
1.24	5.25e-05	GO:0016301	kinase activity
1.24	3.01e-04	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.21	5.32e-04	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.24	2.21e-03	GO:0004672	protein kinase activity
1.26	2.61e-03	GO:0008092	cytoskeletal protein binding
1.27	3.06e-03	GO:0060589	nucleoside-triphosphatase regulator activity
1.41	3.09e-03	GO:0003924	GTPase activity
1.27	3.97e-03	GO:0030695	GTPase regulator activity
1.13	8.59e-03	GO:0016740	transferase activity
1.29	1.73e-02	GO:0042578	phosphoric ester hydrolase activity
1.28	2.30e-02	GO:0005525	GTP binding
1.09	2.33e-02	GO:0003676	nucleic acid binding
1.19	2.41e-02	GO:0042802	identical protein binding
1.25	2.96e-02	GO:0019904	protein domain specific binding
1.33	3.77e-02	GO:0016791	phosphatase activity
1.41	4.54e-02	GO:0004721	phosphoprotein phosphatase activity