Motif ID: MAZ.p2

Z-value: 1.471


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_29817810-0.294.9e-01Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_291168 3.814 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr19_-_291335 3.789 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr8_+_95653272 3.062 ESRP1
epithelial splicing regulatory protein 1
chr8_+_95653399 2.574 ESRP1
epithelial splicing regulatory protein 1
chr8_+_95653340 2.141 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr3_-_10547221 1.726 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr6_+_37137882 1.717 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr7_+_69064316 1.613 AUTS2
autism susceptibility candidate 2
chr1_-_11714738 1.599 NM_012168
FBXO2
F-box protein 2
chr18_+_33877630 1.522 NM_025135
FHOD3
formin homology 2 domain containing 3
chr7_-_98030165 1.456 BAIAP2L1
BAI1-associated protein 2-like 1
chr1_+_955609 1.424 AGRN
agrin
chr1_+_955468 1.403 NM_198576
AGRN
agrin
chr1_-_160068359 1.380 NM_052868
IGSF8
immunoglobulin superfamily, member 8
chr17_-_47841517 1.303 NM_030802
FAM117A
family with sequence similarity 117, member A
chr1_-_175161832 1.287 NM_001162895
NM_014656
NM_001162893
NM_001162894
KIAA0040



KIAA0040



chr1_+_60280462 1.269 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr19_-_15090349 1.251 SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr3_-_13921617 1.233 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr8_+_86376130 1.211 NM_000067
CA2
carbonic anhydrase II
chr8_-_495330 1.202 NM_175075
C8orf42
chromosome 8 open reading frame 42
chr13_-_114018201 1.197 GRTP1
growth hormone regulated TBC protein 1
chr18_-_24129084 1.194 NM_001136205
KCTD1
potassium channel tetramerisation domain containing 1
chr22_+_45148437 1.184 NM_001017526
NM_001198726
NM_181335
ARHGAP8


Rho GTPase activating protein 8


chr8_-_494834 1.179 C8orf42
chromosome 8 open reading frame 42
chr20_+_58179601 1.176 NM_080672
PHACTR3
phosphatase and actin regulator 3
chr10_+_111985628 1.169 NM_005962
MXI1
MAX interactor 1
chr8_-_144650998 1.168 C8orf73
chromosome 8 open reading frame 73
chr1_-_160068617 1.162 NM_001206665
IGSF8
immunoglobulin superfamily, member 8
chr18_-_28681885 1.157 NM_004949
NM_024422
DSC2

desmocollin 2

chr22_+_45064323 1.143 NM_001017528
NM_001017529
PRR5

proline rich 5 (renal)

chr1_+_15250578 1.137 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr12_+_4382882 1.136 NM_001759
CCND2
cyclin D2
chr13_-_114018365 1.105 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr1_+_233463513 1.091 NM_032435
KIAA1804
mixed lineage kinase 4
chr1_-_207205996 1.079 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr1_-_11714471 1.063 FBXO2
F-box protein 2
chr14_-_21994342 1.053 SALL2
sal-like 2 (Drosophila)
chr4_-_819879 1.053 NM_006651
CPLX1
complexin 1
chr1_+_200860619 1.039 NM_018265
C1orf106
chromosome 1 open reading frame 106
chr1_-_160068261 1.013 IGSF8
immunoglobulin superfamily, member 8
chr22_-_43583058 0.981 TTLL12
tubulin tyrosine ligase-like family, member 12
chr12_-_106532447 0.977 NUAK1
NUAK family, SNF1-like kinase, 1
chr1_-_11714396 0.971 FBXO2
F-box protein 2
chr16_+_89778242 0.970 LOC100128881
uncharacterized LOC100128881
chr17_-_47841468 0.969 FAM117A
family with sequence similarity 117, member A
chr11_-_119234628 0.949 USP2
ubiquitin specific peptidase 2
chr19_-_51487070 0.942 NM_139277
NM_001207053
NM_001243126
NM_005046
KLK7



kallikrein-related peptidase 7



chr5_-_141257943 0.941 NM_002587
NM_032420
PCDH1

protocadherin 1

chr22_+_45098091 0.941 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr3_+_50192420 0.939 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr6_+_41606193 0.936 NM_005586
MDFI
MyoD family inhibitor
chr8_-_21988518 0.935 NM_005144
NM_018411
HR

hairless homolog (mouse)

chr1_-_41131323 0.932 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr14_-_95786095 0.930 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr18_-_28681429 0.929 DSC2
desmocollin 2
chr22_-_43583132 0.928 NM_015140
TTLL12
tubulin tyrosine ligase-like family, member 12
chr5_-_175964223 0.928 NM_014901
RNF44
ring finger protein 44
chr14_-_21566497 0.927 ZNF219
zinc finger protein 219
chr1_+_1981902 0.920 NM_002744
PRKCZ
protein kinase C, zeta
chr15_+_101420032 0.913 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr6_+_150464156 0.901 NM_030949
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr14_-_21566728 0.898 NM_016423
ZNF219
zinc finger protein 219
chr10_-_105614952 0.894 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr2_+_85360373 0.891 NM_031283
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr10_-_135090325 0.883 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr6_-_42419782 0.878 NM_033502
TRERF1
transcriptional regulating factor 1
chr5_+_52776263 0.872 NM_006350
NM_013409
FST

follistatin

chr17_+_47572592 0.867 NM_002507
NGFR
nerve growth factor receptor
chr15_+_41136178 0.859 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chrX_-_153141398 0.855 NM_000425
NM_001143963
NM_024003
L1CAM


L1 cell adhesion molecule


chr16_-_402617 0.848 NM_003502
NM_181050
AXIN1

axin 1

chr8_-_57232700 0.844 SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr1_+_160370363 0.842 NM_020335
VANGL2
vang-like 2 (van gogh, Drosophila)
chr22_+_51113069 0.841 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr7_+_145813452 0.840 NM_014141
CNTNAP2
contactin associated protein-like 2
chr19_-_55658310 0.830 TNNT1
troponin T type 1 (skeletal, slow)
chr1_-_117210301 0.813 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr9_-_139948448 0.810 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr17_+_48503518 0.802 NM_025149
ACSF2
acyl-CoA synthetase family member 2
chr2_-_46384 0.801 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr22_-_39639967 0.796 PDGFB
platelet-derived growth factor beta polypeptide
chr15_+_90744506 0.788 NM_198925
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr1_-_201368434 0.780 LAD1
ladinin 1
chr9_-_92112887 0.775 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr8_-_127570710 0.762 NM_174911
FAM84B
family with sequence similarity 84, member B
chr22_+_45098046 0.759 NM_181333
PRR5
proline rich 5 (renal)
chr8_-_10587942 0.756 NM_031439
SOX7
SRY (sex determining region Y)-box 7
chr20_+_62328068 0.748 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr12_+_104850784 0.744 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr12_+_104850762 0.738 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr1_-_242687997 0.737 NM_152666
PLD5
phospholipase D family, member 5
chr15_+_74833517 0.735 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr6_+_30852326 0.728 NM_013993
DDR1
discoidin domain receptor tyrosine kinase 1
chr10_+_82213892 0.727 NM_001128309
NM_030927
TSPAN14

tetraspanin 14

chr1_+_62208091 0.726 NM_176877
INADL
InaD-like (Drosophila)
chr16_+_67465019 0.723 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr3_-_128840605 0.722 NM_001204886
NM_001204887
NM_001204888
NM_198490
NM_001204885
RAB43




RAB43, member RAS oncogene family




chr3_-_128840856 0.721 NM_001204884
NM_001204883
RAB43

RAB43, member RAS oncogene family

chr11_+_1861431 0.720 NM_001145841
TNNI2
troponin I type 2 (skeletal, fast)
chr10_+_82214066 0.719 TSPAN14
tetraspanin 14
chr1_+_184356364 0.719 C1orf21
chromosome 1 open reading frame 21
chr17_+_48503607 0.716 ACSF2
acyl-CoA synthetase family member 2
chr10_-_103535656 0.714 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr12_+_104850986 0.711 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr10_-_103874661 0.706 NM_003893
LDB1
LIM domain binding 1
chr7_+_69063768 0.705 NM_001127231
NM_001127232
NM_015570
AUTS2


autism susceptibility candidate 2


chr1_+_955536 0.697


chr19_-_51523272 0.697 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr12_-_53625834 0.694 NM_000966
NM_001243730
NM_001243731
RARG


retinoic acid receptor, gamma


chr8_-_127570465 0.688 FAM84B
family with sequence similarity 84, member B
chr1_-_32801606 0.687 NM_023009
MARCKSL1
MARCKS-like 1
chr20_-_22564893 0.685 FOXA2
forkhead box A2
chr3_-_128840343 0.681 RAB43
RAB43, member RAS oncogene family
chr15_-_72612497 0.681 NM_052840
CELF6
CUGBP, Elav-like family member 6
chr1_-_1051458 0.678 C1orf159
chromosome 1 open reading frame 159
chr22_+_29468887 0.671 NM_001039570
NM_032045
KREMEN1

kringle containing transmembrane protein 1

chr2_-_60780404 0.670 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr19_-_44143943 0.670 NM_145296
CADM4
cell adhesion molecule 4
chr11_+_394199 0.661 NM_007183
PKP3
plakophilin 3
chr1_+_151483861 0.655 NM_020770
CGN
cingulin
chr1_-_6321034 0.653 NM_207370
GPR153
G protein-coupled receptor 153
chr18_+_19749403 0.648 NM_005257
GATA6
GATA binding protein 6
chr12_+_104850641 0.648 NM_001173982
NM_018413
CHST11

carbohydrate (chondroitin 4) sulfotransferase 11

chr16_-_402398 0.643 AXIN1
axin 1
chr2_+_220306772 0.638 SPEG
SPEG complex locus
chr9_-_124989755 0.638 NM_001242334
LHX6
LIM homeobox 6
chr19_+_34287662 0.632 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr2_-_60780767 0.631 BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr2_-_235405692 0.627 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr10_+_82214074 0.622 TSPAN14
tetraspanin 14
chr3_-_48470715 0.621 NM_002673
PLXNB1
plexin B1
chr20_-_46414636 0.621 NM_018837
SULF2
sulfatase 2
chr10_+_82214071 0.615 TSPAN14
tetraspanin 14
chr17_+_47653474 0.613 NXPH3
neurexophilin 3
chr2_+_220325533 0.607 NM_001173476
SPEG
SPEG complex locus
chr19_+_45754551 0.607 MARK4
MAP/microtubule affinity-regulating kinase 4
chr9_+_133971862 0.605 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr14_-_100070442 0.603 NM_001144995
CCDC85C
coiled-coil domain containing 85C
chr15_-_65067696 0.602 NM_194272
RBPMS2
RNA binding protein with multiple splicing 2
chr4_+_1795004 0.602 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr3_+_50192847 0.599 NM_004186
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr19_+_38755097 0.599 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr1_+_3371020 0.594 NM_014448
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr8_-_75233461 0.594 NM_020647
JPH1
junctophilin 1
chr17_+_73717515 0.593 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr21_+_46825001 0.592 NM_130445
COL18A1
collagen, type XVIII, alpha 1
chr4_-_84255999 0.591 HPSE
heparanase
chr20_-_31071187 0.589 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr2_+_47596447 0.588 EPCAM
epithelial cell adhesion molecule
chr1_-_9970265 0.585 NM_001012329
NM_020248
CTNNBIP1

catenin, beta interacting protein 1

chr1_+_46640748 0.583 NM_005727
TSPAN1
tetraspanin 1
chr13_+_26042965 0.580 ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr8_-_144650884 0.580 C8orf73
chromosome 8 open reading frame 73
chr9_+_116638544 0.579 NM_133374
ZNF618
zinc finger protein 618
chrX_+_152954965 0.579 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr2_+_47596286 0.578 NM_002354
EPCAM
epithelial cell adhesion molecule
chr11_+_124933197 0.578 SLC37A2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr6_+_43738757 0.577 VEGFA
vascular endothelial growth factor A
chr2_-_20424627 0.573 NM_002997
SDC1
syndecan 1
chr9_-_135996287 0.569 NM_006266
RALGDS
ral guanine nucleotide dissociation stimulator
chr4_-_84255895 0.567 NM_001199830
HPSE
heparanase
chr12_-_91572328 0.565 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chr3_-_52444016 0.565 BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr15_-_72612247 0.563 NM_001172684
CELF6
CUGBP, Elav-like family member 6
chr14_-_91526912 0.561 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr3_-_52443893 0.560 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr12_-_54779482 0.557 ZNF385A
zinc finger protein 385A
chr3_-_98241748 0.557 CLDND1
claudin domain containing 1
chr1_+_26856252 0.557 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr20_-_62284701 0.553 NM_015894
STMN3
stathmin-like 3
chr17_+_73717556 0.552 ITGB4
integrin, beta 4
chr1_+_155099935 0.549 EFNA1
ephrin-A1
chr7_-_559479 0.549 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr20_-_18038520 0.546 NM_021220
OVOL2
ovo-like 2 (Drosophila)
chr14_+_61788398 0.546 NM_006255
PRKCH
protein kinase C, eta
chr8_+_120220554 0.544 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr4_-_84256012 0.542 NM_001098540
HPSE
heparanase
chr12_+_50017340 0.540 NM_012272
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr2_-_165477818 0.540 GRB14
growth factor receptor-bound protein 14
chr2_-_74667553 0.538 NM_001015056
NM_033046
RTKN

rhotekin

chr14_+_94640648 0.538 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr16_+_67233013 0.537 NM_024712
ELMO3
engulfment and cell motility 3
chr19_+_38755238 0.537 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr15_+_45422130 0.537 NM_017434
NM_175940
DUOX1

dual oxidase 1

chr18_-_74207145 0.536 NM_014643
ZNF516
zinc finger protein 516
chrX_+_152953751 0.535 NM_001142805
NM_005629
SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

chr4_+_1005395 0.534 FGFRL1
fibroblast growth factor receptor-like 1
chr2_-_165477986 0.533 GRB14
growth factor receptor-bound protein 14
chr4_-_25864430 0.533 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr20_+_1875534 0.532 SIRPA
signal-regulatory protein alpha
chr19_-_36004553 0.531 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr12_+_104850750 0.531 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr18_+_11981421 0.526 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr12_+_70759974 0.526 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr2_+_64681610 0.525 LGALSL
lectin, galactoside-binding-like
chr12_-_54785018 0.525 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chr2_-_122042767 0.523 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr7_+_86273867 0.522 GRM3
glutamate receptor, metabotropic 3
chr6_-_170599568 0.518 NM_005618
DLL1
delta-like 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.09 4.08e-31 GO:0009987 cellular process
1.13 1.09e-22 GO:0050794 regulation of cellular process
1.12 2.66e-21 GO:0065007 biological regulation
1.12 7.87e-21 GO:0050789 regulation of biological process
1.13 4.18e-19 GO:0044237 cellular metabolic process
1.17 3.56e-18 GO:0044260 cellular macromolecule metabolic process
1.12 1.32e-15 GO:0044238 primary metabolic process
1.14 2.36e-15 GO:0043170 macromolecule metabolic process
1.10 8.61e-14 GO:0008152 metabolic process
1.23 6.41e-12 GO:0043412 macromolecule modification
1.23 6.96e-12 GO:0006464 protein modification process
1.21 9.07e-12 GO:0048523 negative regulation of cellular process
1.20 1.45e-11 GO:0048519 negative regulation of biological process
1.19 1.13e-10 GO:0044267 cellular protein metabolic process
1.24 2.76e-10 GO:0009653 anatomical structure morphogenesis
1.15 3.26e-10 GO:0031323 regulation of cellular metabolic process
1.15 9.13e-10 GO:0007275 multicellular organismal development
1.15 9.17e-10 GO:0060255 regulation of macromolecule metabolic process
1.14 1.51e-09 GO:0032502 developmental process
1.14 1.88e-09 GO:0023052 signaling
1.14 4.71e-09 GO:0080090 regulation of primary metabolic process
1.36 5.02e-09 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.35 6.31e-09 GO:0010558 negative regulation of macromolecule biosynthetic process
1.40 6.45e-09 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.15 6.96e-09 GO:0048856 anatomical structure development
1.22 9.99e-09 GO:0023051 regulation of signaling
1.39 1.03e-08 GO:0045892 negative regulation of transcription, DNA-dependent
1.34 1.04e-08 GO:0031327 negative regulation of cellular biosynthetic process
1.30 1.10e-08 GO:0031324 negative regulation of cellular metabolic process
1.16 1.14e-08 GO:0048731 system development
1.28 1.34e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.36 1.66e-08 GO:0010629 negative regulation of gene expression
1.34 2.00e-08 GO:0009890 negative regulation of biosynthetic process
1.13 2.38e-08 GO:0019222 regulation of metabolic process
1.14 2.57e-08 GO:0016043 cellular component organization
1.36 2.71e-08 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 3.27e-08 GO:0010605 negative regulation of macromolecule metabolic process
1.35 3.29e-08 GO:0051172 negative regulation of nitrogen compound metabolic process
1.28 3.90e-08 GO:0009892 negative regulation of metabolic process
1.37 6.17e-08 GO:0051253 negative regulation of RNA metabolic process
1.15 6.87e-08 GO:0019538 protein metabolic process
1.16 9.13e-08 GO:0010468 regulation of gene expression
1.22 1.10e-07 GO:0009966 regulation of signal transduction
1.27 1.28e-07 GO:0006793 phosphorus metabolic process
1.27 1.28e-07 GO:0006796 phosphate metabolic process
1.39 1.53e-07 GO:0048646 anatomical structure formation involved in morphogenesis
1.33 1.63e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.14 1.92e-07 GO:0007165 signal transduction
1.31 3.52e-07 GO:0006468 protein phosphorylation
1.29 3.90e-07 GO:0016310 phosphorylation
1.15 6.41e-07 GO:0048518 positive regulation of biological process
1.16 7.11e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.16 9.77e-07 GO:0051252 regulation of RNA metabolic process
1.13 1.22e-06 GO:0071840 cellular component organization or biogenesis
1.15 1.79e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.26 3.43e-06 GO:0006351 transcription, DNA-dependent
1.20 3.92e-06 GO:0007399 nervous system development
1.14 4.15e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 4.93e-06 GO:0009889 regulation of biosynthetic process
1.15 5.10e-06 GO:0071842 cellular component organization at cellular level
1.14 5.46e-06 GO:0031326 regulation of cellular biosynthetic process
1.15 5.92e-06 GO:0044249 cellular biosynthetic process
1.14 6.11e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.40 6.98e-06 GO:0009792 embryo development ending in birth or egg hatching
1.40 7.28e-06 GO:0043009 chordate embryonic development
1.16 7.95e-06 GO:0006355 regulation of transcription, DNA-dependent
1.15 1.36e-05 GO:0048522 positive regulation of cellular process
1.10 3.82e-05 GO:0051716 cellular response to stimulus
1.16 4.81e-05 GO:0030154 cell differentiation
1.15 4.99e-05 GO:0048869 cellular developmental process
1.22 5.53e-05 GO:0010646 regulation of cell communication
1.27 6.70e-05 GO:0009790 embryo development
1.36 7.04e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.13 7.42e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 8.00e-05 GO:0030182 neuron differentiation
1.23 1.18e-04 GO:0048468 cell development
1.14 1.30e-04 GO:0009058 biosynthetic process
1.13 1.95e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.16 2.50e-04 GO:0048583 regulation of response to stimulus
1.26 3.36e-04 GO:0045595 regulation of cell differentiation
1.23 5.17e-04 GO:0048699 generation of neurons
1.16 5.28e-04 GO:0016070 RNA metabolic process
1.21 6.89e-04 GO:0032774 RNA biosynthetic process
1.22 7.97e-04 GO:0022008 neurogenesis
1.16 8.77e-04 GO:0034645 cellular macromolecule biosynthetic process
1.11 9.25e-04 GO:0006807 nitrogen compound metabolic process
1.11 1.12e-03 GO:0034641 cellular nitrogen compound metabolic process
1.29 1.45e-03 GO:0019226 transmission of nerve impulse
1.29 1.45e-03 GO:0035637 multicellular organismal signaling
1.31 1.61e-03 GO:0007268 synaptic transmission
1.15 1.74e-03 GO:0010467 gene expression
1.15 1.96e-03 GO:0009059 macromolecule biosynthetic process
1.20 2.15e-03 GO:0032268 regulation of cellular protein metabolic process
1.26 2.60e-03 GO:0009887 organ morphogenesis
1.13 2.97e-03 GO:0090304 nucleic acid metabolic process
1.10 3.04e-03 GO:0051179 localization
1.41 4.05e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.42 6.57e-03 GO:0001701 in utero embryonic development
1.18 1.02e-02 GO:0051246 regulation of protein metabolic process
1.31 1.06e-02 GO:0016568 chromatin modification
1.72 1.52e-02 GO:0031124 mRNA 3'-end processing
1.10 1.64e-02 GO:0051234 establishment of localization
1.24 1.85e-02 GO:0048666 neuron development
1.19 2.03e-02 GO:0050793 regulation of developmental process
1.23 2.53e-02 GO:0030030 cell projection organization
1.15 2.86e-02 GO:0035556 intracellular signal transduction
1.32 3.70e-02 GO:0060284 regulation of cell development
1.14 4.11e-02 GO:0006996 organelle organization
1.10 4.47e-02 GO:0006810 transport
1.41 4.58e-02 GO:0016569 covalent chromatin modification

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 2.61e-35 GO:0005622 intracellular
1.09 1.08e-33 GO:0044424 intracellular part
1.10 1.98e-23 GO:0043227 membrane-bounded organelle
1.10 2.21e-23 GO:0043231 intracellular membrane-bounded organelle
1.11 2.60e-22 GO:0005737 cytoplasm
1.14 1.47e-20 GO:0005634 nucleus
1.09 2.66e-20 GO:0043229 intracellular organelle
1.09 3.07e-20 GO:0043226 organelle
1.10 4.24e-10 GO:0044444 cytoplasmic part
1.03 9.32e-10 GO:0044464 cell part
1.03 1.06e-09 GO:0005623 cell
1.18 2.22e-08 GO:0005829 cytosol
1.17 5.32e-08 GO:0070013 intracellular organelle lumen
1.16 7.85e-08 GO:0043233 organelle lumen
1.16 1.13e-07 GO:0031974 membrane-enclosed lumen
1.17 6.30e-07 GO:0031981 nuclear lumen
1.20 1.13e-06 GO:0005654 nucleoplasm
1.15 4.17e-06 GO:0044428 nuclear part
1.08 2.33e-05 GO:0044422 organelle part
1.08 4.76e-05 GO:0044446 intracellular organelle part
1.24 1.57e-03 GO:0030054 cell junction
1.30 3.83e-03 GO:0048471 perinuclear region of cytoplasm
1.42 6.85e-03 GO:0070161 anchoring junction
1.20 1.37e-02 GO:0044451 nucleoplasm part
1.09 2.18e-02 GO:0043234 protein complex
1.15 2.38e-02 GO:0005783 endoplasmic reticulum

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 4.66e-32 GO:0005515 protein binding
1.08 3.87e-31 GO:0005488 binding
1.28 7.15e-10 GO:0001071 nucleic acid binding transcription factor activity
1.28 7.15e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.30 1.11e-07 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.28 3.92e-07 GO:0016301 kinase activity
1.30 4.47e-07 GO:0043565 sequence-specific DNA binding
1.24 1.27e-06 GO:0030528 transcription regulator activity
1.30 3.86e-06 GO:0004672 protein kinase activity
1.14 1.53e-05 GO:0000166 nucleotide binding
1.14 4.12e-05 GO:0003677 DNA binding
1.23 5.04e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.25 7.09e-05 GO:0019899 enzyme binding
1.17 1.14e-04 GO:0032559 adenyl ribonucleotide binding
1.16 1.77e-04 GO:0030554 adenyl nucleotide binding
1.16 2.32e-04 GO:0005524 ATP binding
1.31 3.30e-04 GO:0004674 protein serine/threonine kinase activity
1.10 3.94e-04 GO:0003676 nucleic acid binding
1.09 4.85e-04 GO:0043169 cation binding
1.14 5.72e-04 GO:0032553 ribonucleotide binding
1.14 5.72e-04 GO:0032555 purine ribonucleotide binding
1.14 8.03e-04 GO:0017076 purine nucleotide binding
1.09 8.29e-04 GO:0043167 ion binding
1.09 8.30e-04 GO:0046872 metal ion binding
1.14 8.42e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.33 3.25e-03 GO:0016564 transcription repressor activity
1.28 3.67e-03 GO:0019904 protein domain specific binding
1.49 4.95e-03 GO:0004713 protein tyrosine kinase activity
1.25 1.48e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.32 3.07e-02 GO:0005261 cation channel activity
1.54 3.17e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.20 3.64e-02 GO:0046983 protein dimerization activity
1.24 4.32e-02 GO:0030695 GTPase regulator activity