Motif ID: MTF1.p2

Z-value: 1.134


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
MTF1 4520 metal-regulatory transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MTF1chr1_-_38325224-0.285.0e-01Click!


Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_46414636 0.564 NM_018837
SULF2
sulfatase 2
chr5_+_176237435 0.526 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chr7_-_150864866 0.462 NM_001098834
GBX1
gastrulation brain homeobox 1
chr19_+_54371170 0.410 MYADM
myeloid-associated differentiation marker
chr9_-_95896498 0.399 NM_004148
NINJ1
ninjurin 1
chr1_-_6321034 0.389 NM_207370
GPR153
G protein-coupled receptor 153
chr9_+_133320093 0.384 NM_000050
NM_054012
ASS1

argininosuccinate synthase 1

chr6_+_150464156 0.378 NM_030949
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr9_+_133320247 0.367 ASS1
argininosuccinate synthase 1
chr20_+_20348744 0.343 NM_002196
INSM1
insulinoma-associated 1
chr16_+_56666533 0.340 NM_176870
MT1M
metallothionein 1M
chr8_-_110704019 0.332 NM_001099743
NM_001099744
SYBU

syntabulin (syntaxin-interacting)

chr13_-_20806533 0.332 NM_001110219
NM_001110220
NM_001110221
GJB6


gap junction protein, beta 6, 30kDa


chr12_-_22487566 0.326 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr4_+_95679075 0.306 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr6_+_56819706 0.297 NM_152731
BEND6
BEN domain containing 6
chr19_-_15090349 0.287 SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr22_-_46933066 0.287 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr1_-_108507474 0.286 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr17_+_48503607 0.277 ACSF2
acyl-CoA synthetase family member 2
chr7_-_143105897 0.275 NM_005232
EPHA1
EPH receptor A1
chr17_+_48503518 0.273 NM_025149
ACSF2
acyl-CoA synthetase family member 2
chr11_-_1769086 0.270 IFITM10
interferon induced transmembrane protein 10
chr13_-_114018201 0.262 GRTP1
growth hormone regulated TBC protein 1
chr6_-_99797530 0.261 NM_032511
C6orf168
chromosome 6 open reading frame 168
chr2_+_47596286 0.261 NM_002354
EPCAM
epithelial cell adhesion molecule
chr19_-_70944 0.260 WASH5P
WAS protein family homolog 5 pseudogene
chr19_+_38755097 0.257 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr15_-_93616308 0.252 RGMA
RGM domain family, member A
chr5_+_65892139 0.250 NM_001164664
NM_198828
MAST4

microtubule associated serine/threonine kinase family member 4

chr20_+_6748744 0.248 NM_001200
BMP2
bone morphogenetic protein 2
chr8_+_1712011 0.246 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr7_+_150811719 0.244 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr2_+_220306772 0.244 SPEG
SPEG complex locus
chr9_+_214867 0.242 DOCK8
dedicator of cytokinesis 8
chr13_-_20767100 0.242 NM_004004
GJB2
gap junction protein, beta 2, 26kDa
chr2_+_121103670 0.239 NM_002193
INHBB
inhibin, beta B
chr11_-_2016743 0.238 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr17_-_5404304 0.235 NM_001162371
LOC728392
uncharacterized LOC728392
chr10_+_120789227 0.230 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr18_-_74207145 0.227 NM_014643
ZNF516
zinc finger protein 516
chr8_-_22549901 0.226 NM_001199880
EGR3
early growth response 3
chr8_-_48650703 0.225 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr21_+_44073650 0.223 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr9_-_140317650 0.223 EXD3
exonuclease 3'-5' domain containing 3
chr8_-_121824287 0.220 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr10_-_103535656 0.220 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr15_-_29862926 0.219 NM_015307
FAM189A1
family with sequence similarity 189, member A1
chr2_+_47596447 0.217 EPCAM
epithelial cell adhesion molecule
chr2_+_219187858 0.216 NM_022572
PNKD
paroxysmal nonkinesigenic dyskinesia
chr6_+_146136030 0.216 LOC100507557
uncharacterized LOC100507557
chr11_+_121322848 0.215 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr15_-_93616358 0.215 NM_001166286
RGMA
RGM domain family, member A
chr2_-_46384 0.211 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr11_+_65779461 0.210 NM_001323
CST6
cystatin E/M
chr3_-_124931562 0.210 NM_024628
SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr7_+_30324611 0.210 ZNRF2
zinc and ring finger 2
chr2_+_14772809 0.206 NM_145175
FAM84A
family with sequence similarity 84, member A
chr1_-_3528058 0.206 NM_001409
MEGF6
multiple EGF-like-domains 6
chr6_+_160769365 0.205 NM_021977
SLC22A3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr4_+_30722445 0.204 PCDH7
protocadherin 7
chr2_+_7057471 0.203 NM_014746
RNF144A
ring finger protein 144A
chr3_+_71803200 0.202 NM_018971
GPR27
G protein-coupled receptor 27
chr8_-_140715234 0.202 NM_016601
KCNK9
potassium channel, subfamily K, member 9
chr18_+_43913906 0.202 RNF165
ring finger protein 165
chr19_+_33685489 0.199 NM_002333
LRP3
low density lipoprotein receptor-related protein 3
chr8_-_48650683 0.199 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr3_-_10749715 0.197 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr3_-_13921617 0.197 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr1_+_226250421 0.197 H3F3A
H3F3AP4
H3 histone, family 3A
H3 histone, family 3A, pseudogene 4
chr6_+_7541863 0.196 NM_001008844
NM_004415
DSP

desmoplakin

chr11_+_369723 0.196 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr21_-_42219038 0.195 NM_001389
DSCAM
Down syndrome cell adhesion molecule
chr13_+_37006408 0.190 NM_001111045
NM_003914
CCNA1

cyclin A1

chr18_-_500583 0.189 NM_130386
COLEC12
collectin sub-family member 12
chr9_-_140317713 0.186 NM_017820
EXD3
exonuclease 3'-5' domain containing 3
chr11_+_58939539 0.186 NM_015177
DTX4
deltex homolog 4 (Drosophila)
chr9_-_112260529 0.186 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr9_+_116918230 0.185 NM_032888
COL27A1
collagen, type XXVII, alpha 1
chr20_-_36889173 0.185 NM_001029864
KIAA1755
KIAA1755
chr14_-_105634708 0.184 JAG2
jagged 2
chr7_+_2559396 0.183 NM_001040167
NM_001040168
LFNG

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr4_-_53617781 0.183 NM_001242690
NM_024534
ERVMER34-1

endogenous retrovirus group MER34, member 1

chr3_+_36421944 0.181 NM_003149
STAC
SH3 and cysteine rich domain
chr9_+_140317803 0.180 NM_006647
NOXA1
NADPH oxidase activator 1
chr13_-_41240607 0.180 NM_002015
FOXO1
forkhead box O1
chr18_+_33877630 0.179 NM_025135
FHOD3
formin homology 2 domain containing 3
chr11_+_58939960 0.177 DTX4
deltex homolog 4 (Drosophila)
chr18_-_78005230 0.176 NM_032510
PARD6G
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr12_+_57610577 0.175 NM_007224
NXPH4
neurexophilin 4
chr13_-_20767036 0.175 GJB2
gap junction protein, beta 2, 26kDa
chr2_+_207308280 0.175 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr22_-_20255614 0.174 NM_023004
RTN4R
reticulon 4 receptor
chr7_+_86274076 0.171 GRM3
glutamate receptor, metabotropic 3
chr1_-_6479880 0.171 NM_019089
HES2
hairy and enhancer of split 2 (Drosophila)
chr1_+_109792640 0.171 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr10_-_135238075 0.170 NM_001012508
SPRN
shadow of prion protein homolog (zebrafish)
chr7_+_142552547 0.170 NM_004445
EPHB6
EPH receptor B6
chr14_-_21566497 0.169 ZNF219
zinc finger protein 219
chr16_-_79634610 0.169 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr6_+_7541837 0.169 DSP
desmoplakin
chr9_-_94186140 0.168 NM_005384
NFIL3
nuclear factor, interleukin 3 regulated
chr15_+_62682682 0.167 TLN2
talin 2
chr6_-_16761600 0.165 NM_000332
NM_001128164
ATXN1

ataxin 1

chr17_-_74581934 0.165 ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr12_-_123635284 0.164 PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr7_+_86273867 0.164 GRM3
glutamate receptor, metabotropic 3
chr21_+_46825001 0.164 NM_130445
COL18A1
collagen, type XVIII, alpha 1
chr7_+_30324504 0.164 ZNRF2
zinc and ring finger 2
chr1_+_15250578 0.164 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr22_-_51021255 0.163 CHKB
choline kinase beta
chr8_-_121824268 0.163 SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr13_+_37005966 0.162 NM_001111046
NM_001111047
CCNA1

cyclin A1

chr17_+_9548853 0.162 NM_153210
USP43
ubiquitin specific peptidase 43
chr11_+_10472223 0.161 NM_000480
AMPD3
adenosine monophosphate deaminase 3
chr1_+_45769551 0.161 LOC400752
uncharacterized LOC400752
chr17_-_66596934 0.161 NM_001243746
NM_017565
FAM20A

family with sequence similarity 20, member A

chr8_+_1711869 0.160 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr14_-_21566728 0.159 NM_016423
ZNF219
zinc finger protein 219
chr22_+_38035718 0.159 SH3BP1
SH3-domain binding protein 1
chr8_+_145515244 0.158 NM_005526
HSF1
heat shock transcription factor 1
chr19_-_36523770 0.158 NM_015526
CLIP3
CAP-GLY domain containing linker protein 3
chr1_+_233463513 0.158 NM_032435
KIAA1804
mixed lineage kinase 4
chr17_-_36762105 0.158 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr5_+_52776263 0.158 NM_006350
NM_013409
FST

follistatin

chr12_+_107712151 0.158 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chrX_+_135229536 0.157 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr8_+_145515279 0.157 HSF1
heat shock transcription factor 1
chr17_-_74582144 0.157 NM_006456
ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr22_-_51021200 0.156 CHKB
choline kinase beta
chr21_+_46825291 0.156


chr6_+_72596699 0.155 RIMS1
regulating synaptic membrane exocytosis 1
chr5_+_68788387 0.155 NM_001205254
OCLN
occludin
chr11_+_706103 0.155 NM_022772
EPS8L2
EPS8-like 2
chr18_+_11689135 0.155 NM_182978
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr1_+_33722158 0.154 NM_152493
ZNF362
zinc finger protein 362
chr10_-_135090325 0.153 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr4_+_30722191 0.153 PCDH7
protocadherin 7
chr9_-_5832840 0.153 ERMP1
endoplasmic reticulum metallopeptidase 1
chr21_+_42540054 0.152 BACE2
beta-site APP-cleaving enzyme 2
chr1_+_27561006 0.152 NM_015023
WDTC1
WD and tetratricopeptide repeats 1
chr19_+_38755238 0.151 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr1_-_935469 0.151 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr9_-_96717627 0.151 BARX1
BARX homeobox 1
chr9_-_5833072 0.150 NM_024896
ERMP1
endoplasmic reticulum metallopeptidase 1
chr21_+_18885296 0.149 CXADR
coxsackie virus and adenovirus receptor
chr1_+_6052357 0.149 NM_001199861
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr4_+_30721865 0.148 NM_032456
NM_001173523
NM_002589
NM_032457
PCDH7



protocadherin 7



chr5_-_16617085 0.148 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr17_+_8924822 0.148 NM_004822
NTN1
netrin 1
chr10_+_11060105 0.148 CELF2
CUGBP, Elav-like family member 2
chr21_-_42218587 0.147 DSCAM
Down syndrome cell adhesion molecule
chr19_-_19738973 0.147 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr1_+_38273817 0.147 C1orf122
chromosome 1 open reading frame 122
chr8_+_141521526 0.147 CHRAC1
chromatin accessibility complex 1
chr9_+_101705710 0.147 NM_001855
COL15A1
collagen, type XV, alpha 1
chr12_+_133067156 0.147 NM_001142641
FBRSL1
fibrosin-like 1
chr3_+_50192420 0.146 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr8_-_125740650 0.146 NM_014751
MTSS1
metastasis suppressor 1
chr1_-_44497028 0.145 SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr17_-_74581881 0.144 ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr9_+_116638544 0.143 NM_133374
ZNF618
zinc finger protein 618
chr1_+_92495484 0.143 NM_173567
EPHX4
epoxide hydrolase 4
chr9_-_140317583 0.142 EXD3
exonuclease 3'-5' domain containing 3
chr15_+_65134081 0.142 NM_001195059
NM_025201
PLEKHO2

pleckstrin homology domain containing, family O member 2

chr3_-_57113292 0.141 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr9_-_94185959 0.139 NFIL3
nuclear factor, interleukin 3 regulated
chr22_+_43506753 0.139 NM_001197
BIK
BCL2-interacting killer (apoptosis-inducing)
chr7_-_44365019 0.138 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr7_+_18126543 0.138 NM_001204144
HDAC9
histone deacetylase 9
chr2_+_219187975 0.137 PNKD
paroxysmal nonkinesigenic dyskinesia
chr3_+_16926451 0.137 NM_001144382
PLCL2
phospholipase C-like 2
chr2_-_97303983 0.137 KANSL3
KAT8 regulatory NSL complex subunit 3
chr21_+_42540092 0.136 BACE2
beta-site APP-cleaving enzyme 2
chr21_+_42797977 0.135 NM_002462
NM_001178046
MX1

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

chr1_+_203274646 0.135 NM_006763
BTG2
BTG family, member 2
chr6_-_170599568 0.134 NM_005618
DLL1
delta-like 1 (Drosophila)
chr1_+_1981902 0.133 NM_002744
PRKCZ
protein kinase C, zeta
chr8_+_22436253 0.133 NM_021630
PDLIM2
PDZ and LIM domain 2 (mystique)
chr8_-_127570710 0.133 NM_174911
FAM84B
family with sequence similarity 84, member B
chr8_+_61591358 0.132 CHD7
chromodomain helicase DNA binding protein 7
chr9_-_96717544 0.131 NM_021570
BARX1
BARX homeobox 1
chr15_+_40545348 0.131 PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr8_+_144099900 0.131 NM_001127213
NM_002346
LY6E

lymphocyte antigen 6 complex, locus E

chr9_+_137218313 0.131 NM_002957
RXRA
retinoid X receptor, alpha
chr6_+_36098261 0.130 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr17_+_27920479 0.130 NM_152345
ANKRD13B
ankyrin repeat domain 13B
chrX_+_117861523 0.129 NM_001560
IL13RA1
interleukin 13 receptor, alpha 1
chr10_+_111969988 0.129 NM_001008541
MXI1
MAX interactor 1
chr11_+_48002120 0.129 PTPRJ
protein tyrosine phosphatase, receptor type, J
chr16_+_84002099 0.126 NM_019065
NECAB2
N-terminal EF-hand calcium binding protein 2
chr6_+_35227478 0.126 NM_003427
ZNF76
zinc finger protein 76
chr19_+_10196972 0.126 C19orf66
chromosome 19 open reading frame 66
chr11_-_65325391 0.126 LTBP3
latent transforming growth factor beta binding protein 3
chr19_+_751108 0.125 NM_173481
C19orf21
chromosome 19 open reading frame 21
chr22_+_38035683 0.125 NM_018957
SH3BP1
SH3-domain binding protein 1
chr2_-_97304080 0.124 NM_001115016
NM_017991
KANSL3

KAT8 regulatory NSL complex subunit 3

chrY_-_21154560 0.124 NM_013230
CD24
CD24P4
CD24 molecule
CD24 molecule pseudogene 4
chr1_+_245133283 0.124 EFCAB2
EF-hand calcium binding domain 2
chr20_+_49348050 0.123 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.13 4.15e-08 GO:0050794 regulation of cellular process
1.12 5.55e-08 GO:0065007 biological regulation
1.21 7.26e-08 GO:0023052 signaling
1.33 1.76e-07 GO:0023051 regulation of signaling
1.35 1.96e-07 GO:0007399 nervous system development
1.34 3.24e-07 GO:0009653 anatomical structure morphogenesis
1.30 4.23e-07 GO:0006464 protein modification process
1.23 5.27e-07 GO:0048731 system development
1.27 8.50e-07 GO:0048523 negative regulation of cellular process
1.12 8.76e-07 GO:0050789 regulation of biological process
1.50 1.14e-06 GO:0030182 neuron differentiation
1.21 1.46e-06 GO:0048856 anatomical structure development
1.42 3.89e-06 GO:0022008 neurogenesis
1.43 6.98e-06 GO:0048699 generation of neurons
1.38 7.69e-06 GO:0010646 regulation of cell communication
1.24 8.11e-06 GO:0048519 negative regulation of biological process
1.27 8.82e-06 GO:0043412 macromolecule modification
1.41 9.28e-06 GO:0048468 cell development
1.18 1.10e-05 GO:0032502 developmental process
1.19 1.12e-05 GO:0007275 multicellular organismal development
1.31 3.75e-05 GO:0009966 regulation of signal transduction
1.18 7.31e-05 GO:0007165 signal transduction
1.07 8.13e-05 GO:0009987 cellular process
1.35 2.61e-04 GO:0006793 phosphorus metabolic process
1.35 2.61e-04 GO:0006796 phosphate metabolic process
1.50 4.18e-04 GO:0019226 transmission of nerve impulse
1.50 4.18e-04 GO:0035637 multicellular organismal signaling
1.45 4.71e-04 GO:0009887 organ morphogenesis
1.50 4.96e-04 GO:0000904 cell morphogenesis involved in differentiation
1.49 5.18e-04 GO:0007417 central nervous system development
1.24 6.38e-04 GO:0048513 organ development
1.49 7.40e-04 GO:0031175 neuron projection development
1.39 1.00e-03 GO:0006468 protein phosphorylation
1.50 1.38e-03 GO:0048812 neuron projection morphogenesis
1.51 1.52e-03 GO:0007268 synaptic transmission
1.51 1.52e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
2.01 1.67e-03 GO:0060541 respiratory system development
1.78 2.40e-03 GO:0014070 response to organic cyclic compound
1.43 2.41e-03 GO:0048666 neuron development
1.42 2.49e-03 GO:0000902 cell morphogenesis
2.14 2.90e-03 GO:0060828 regulation of canonical Wnt receptor signaling pathway
1.92 2.92e-03 GO:0030111 regulation of Wnt receptor signaling pathway
1.50 3.33e-03 GO:0007409 axonogenesis
1.21 3.95e-03 GO:0030154 cell differentiation
2.10 3.98e-03 GO:0001505 regulation of neurotransmitter levels
1.21 4.90e-03 GO:0048869 cellular developmental process
2.00 5.91e-03 GO:0006836 neurotransmitter transport
1.14 6.03e-03 GO:0051716 cellular response to stimulus
1.44 6.05e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.39 7.53e-03 GO:0032989 cellular component morphogenesis
1.18 8.51e-03 GO:0044267 cellular protein metabolic process
1.30 9.74e-03 GO:0007154 cell communication
2.26 1.15e-02 GO:0007269 neurotransmitter secretion
1.37 1.66e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.37 1.88e-02 GO:0030030 cell projection organization
1.37 1.89e-02 GO:0001932 regulation of protein phosphorylation
1.32 1.97e-02 GO:0016310 phosphorylation
1.35 2.70e-02 GO:0009890 negative regulation of biosynthetic process
1.41 3.05e-02 GO:0048858 cell projection morphogenesis
1.41 3.06e-02 GO:0032990 cell part morphogenesis
1.35 3.11e-02 GO:0042325 regulation of phosphorylation
1.37 3.40e-02 GO:0010629 negative regulation of gene expression
1.14 4.94e-02 GO:0080090 regulation of primary metabolic process
1.47 4.95e-02 GO:0007420 brain development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.05 7.03e-03 GO:0005622 intracellular
1.05 7.71e-03 GO:0044424 intracellular part
1.42 1.72e-02 GO:0045202 synapse
1.17 2.39e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 1.08e-05 GO:0005515 protein binding
1.06 3.47e-05 GO:0005488 binding
1.43 1.99e-04 GO:0004672 protein kinase activity
1.37 6.51e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.34 1.95e-03 GO:0016301 kinase activity
1.29 4.58e-03 GO:0001071 nucleic acid binding transcription factor activity
1.29 4.58e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.28 2.13e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
4.74 2.15e-02 GO:0031624 ubiquitin conjugating enzyme binding