Motif ID: MYOD1.p2

Z-value: 0.792


Transcription factors associated with MYOD1.p2:

Gene SymbolEntrez IDGene Name
MYOD1 4654 myogenic differentiation 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYOD1chr11_+_177411090.078.6e-01Click!


Activity profile for motif MYOD1.p2.

activity profile for motif MYOD1.p2


Sorted Z-values histogram for motif MYOD1.p2

Sorted Z-values for motif MYOD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYOD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_1769086 0.802 IFITM10
interferon induced transmembrane protein 10
chr5_+_95067511 0.383


chr17_+_39382878 0.366 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr9_+_17578952 0.306 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr21_+_47531369 0.300 COL6A2
collagen, type VI, alpha 2
chr10_+_120789227 0.292 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr19_-_49222956 0.277 NM_001130915
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr14_-_30396811 0.268 NM_002742
PRKD1
protein kinase D1
chr10_-_21462987 0.265 NEBL
nebulette
chr12_+_56075329 0.261 NM_152637
METTL7B
methyltransferase like 7B
chr12_+_56075418 0.260 METTL7B
methyltransferase like 7B
chr10_-_124605690 0.250 NM_022034
CUZD1
CUB and zona pellucida-like domains 1
chr19_-_7939325 0.247 NM_001190467
FLJ22184
putative uncharacterized protein FLJ22184
chr11_-_111782447 0.246 NM_001885
CRYAB
crystallin, alpha B
chr10_-_21463019 0.246 NM_001173484
NM_213569
NEBL

nebulette

chr16_-_4987056 0.236 NM_002705
PPL
periplakin
chr1_+_89990396 0.234 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr7_-_45960738 0.231 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr17_+_73717556 0.224 ITGB4
integrin, beta 4
chr5_+_176237435 0.207 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chrX_+_118108595 0.203 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chrX_-_151143096 0.201 NM_004961
GABRE
gamma-aminobutyric acid (GABA) A receptor, epsilon
chr19_+_41222915 0.195 NM_025194
ITPKC
inositol-trisphosphate 3-kinase C
chrX_+_118108575 0.194 LONRF3
LON peptidase N-terminal domain and ring finger 3
chr7_-_137531585 0.192 NM_004717
DGKI
diacylglycerol kinase, iota
chr15_+_41056243 0.188 NM_005258
GCHFR
GTP cyclohydrolase I feedback regulator
chr8_+_1922030 0.185 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr17_+_73717596 0.181 ITGB4
integrin, beta 4
chr19_+_50016435 0.181 NM_004107
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_+_92702788 0.181 NM_005959
MTNR1B
melatonin receptor 1B
chr2_-_224467049 0.179 SCG2
secretogranin II
chr19_+_41223282 0.179 ITPKC
inositol-trisphosphate 3-kinase C
chr2_-_224467142 0.177 NM_003469
SCG2
secretogranin II
chr2_-_224467095 0.174 SCG2
secretogranin II
chr2_-_133427624 0.173 LYPD1
LY6/PLAUR domain containing 1
chr9_+_92219926 0.170 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr11_+_1874199 0.169 NM_002339
LSP1
lymphocyte-specific protein 1
chr9_+_34990715 0.168 DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr1_+_38273817 0.167 C1orf122
chromosome 1 open reading frame 122
chr10_+_104613966 0.166 NM_001136200
NM_144591
C10orf32-AS3MT
C10orf32

C10orf32-AS3MT readthrough
chromosome 10 open reading frame 32

chr10_-_64576074 0.165 EGR2
early growth response 2
chr12_-_7245006 0.164 NM_001733
C1R
complement component 1, r subcomponent
chr17_+_39394269 0.163 NM_031963
KRTAP9-8
keratin associated protein 9-8
chr5_+_131630065 0.162 NM_003059
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
chr9_-_74061819 0.161 TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr17_+_73717515 0.159 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr10_-_64576123 0.158 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr5_+_75699003 0.156 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr12_-_56101667 0.155 NM_001144996
NM_002206
ITGA7

integrin, alpha 7

chr18_-_74691951 0.155 MBP
myelin basic protein
chr5_+_145718586 0.154 NM_002700
POU4F3
POU class 4 homeobox 3
chr3_-_48470715 0.154 NM_002673
PLXNB1
plexin B1
chr12_-_56101465 0.152 ITGA7
integrin, alpha 7
chr6_-_117747017 0.149 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr3_-_48594209 0.149 NM_004567
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr7_+_70597788 0.147 NM_022479
WBSCR17
Williams-Beuren syndrome chromosome region 17
chr11_+_73358593 0.146 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr5_+_139027868 0.144 CXXC5
CXXC finger protein 5
chr3_-_99833348 0.144 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr9_+_90112754 0.143 NM_004938
DAPK1
death-associated protein kinase 1
chr6_+_96463844 0.143 NM_006581
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr19_+_18794487 0.142 CRTC1
CREB regulated transcription coactivator 1
chr22_+_31003069 0.141 NM_000355
NM_001184726
TCN2

transcobalamin II

chr19_+_14544216 0.141 PKN1
protein kinase N1
chr8_+_104383701 0.141 CTHRC1
collagen triple helix repeat containing 1
chr8_+_72756218 0.140 LOC100132891
uncharacterized LOC100132891
chr3_-_87040246 0.140 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr16_-_54318889 0.139 IRX3
iroquois homeobox 3
chr8_+_72756335 0.138


chr7_+_2557496 0.136 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr20_+_23420321 0.135 NM_138283
CSTL1
cystatin-like 1
chr1_-_40254510 0.135 BMP8B
bone morphogenetic protein 8b
chr5_+_5140442 0.133 NM_139056
ADAMTS16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr10_-_13043570 0.133 NM_031455
CCDC3
coiled-coil domain containing 3
chr1_+_118148506 0.133 NM_017709
FAM46C
family with sequence similarity 46, member C
chr5_+_156693051 0.132 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr3_+_45927995 0.131 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr2_-_133428480 0.131 NM_144586
LYPD1
LY6/PLAUR domain containing 1
chr2_-_85829757 0.129 NM_001031738
TMEM150A
transmembrane protein 150A
chr11_+_27015833 0.128 FIBIN
fin bud initiation factor homolog (zebrafish)
chr1_-_27339326 0.128 NM_052943
FAM46B
family with sequence similarity 46, member B
chr8_+_38831667 0.127 NM_153692
HTRA4
HtrA serine peptidase 4
chr3_+_39851028 0.126 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr16_+_4385141 0.126 GLIS2
GLIS family zinc finger 2
chrX_-_15872938 0.124 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr8_+_17433941 0.124 NM_006207
PDGFRL
platelet-derived growth factor receptor-like
chrX_-_15872871 0.124 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr21_-_39288661 0.122 NM_002240
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr3_-_48471401 0.121 NM_001130082
PLXNB1
plexin B1
chr20_-_39995497 0.120 NM_052846
EMILIN3
elastin microfibril interfacer 3
chr5_-_41510627 0.120 NM_001005473
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr14_+_24605366 0.119 NM_006263
NM_176783
PSME1

proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)

chr19_-_46285746 0.119 DMPK
dystrophia myotonica-protein kinase
chr17_+_26800657 0.117 NM_001145975
NM_001145976
NM_003984
SLC13A2


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2


chr4_-_46391393 0.117 NM_001114175
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr5_-_75919051 0.117 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr7_-_131241321 0.116 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr1_-_27339448 0.116 FAM46B
family with sequence similarity 46, member B
chr8_-_124553253 0.116 FBXO32
F-box protein 32
chr15_-_81616439 0.115 NM_181900
STARD5
StAR-related lipid transfer (START) domain containing 5
chr20_-_44455932 0.115 NM_003279
TNNC2
troponin C type 2 (fast)
chr6_+_168841829 0.115 NM_001166412
NM_022138
SMOC2

SPARC related modular calcium binding 2

chr2_-_190044330 0.114 NM_000393
COL5A2
collagen, type V, alpha 2
chr4_-_142054431 0.114 NM_020724
RNF150
ring finger protein 150
chr17_+_39405938 0.113 NM_033191
KRTAP9-4
keratin associated protein 9-4
chr19_+_50016606 0.113 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr7_-_124405029 0.113 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chrX_+_118109314 0.113 LONRF3
LON peptidase N-terminal domain and ring finger 3
chr1_+_27668499 0.113 SYTL1
synaptotagmin-like 1
chr6_-_24911194 0.113 NM_014722
FAM65B
family with sequence similarity 65, member B
chr13_-_26625164 0.112 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr5_-_66492574 0.112 NM_005582
CD180
CD180 molecule
chr11_-_77899640 0.111 NM_001029859
KCTD21
potassium channel tetramerisation domain containing 21
chr10_-_98480174 0.111 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr2_+_217498082 0.110 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr5_+_139028483 0.110 CXXC5
CXXC finger protein 5
chr22_-_21905372 0.110 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr4_-_159092509 0.110 FAM198B
family with sequence similarity 198, member B
chr1_-_145075636 0.109 NM_022359
PDE4DIP
phosphodiesterase 4D interacting protein
chr2_+_217498205 0.108 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr1_-_168698412 0.107 NM_001937
DPT
dermatopontin
chr19_-_46285645 0.107 DMPK
dystrophia myotonica-protein kinase
chr4_-_46391771 0.107 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr19_-_39368889 0.106 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr20_+_44519590 0.106 NM_000308
NM_001127695
NM_001167594
CTSA


cathepsin A


chr20_+_54933982 0.106 NM_080821
FAM210B
family with sequence similarity 210, member B
chr4_+_134073180 0.105 PCDH10
protocadherin 10
chr12_+_90102639 0.104 LOC338758
uncharacterized LOC338758
chr2_+_205410465 0.104 NM_057177
NM_152526
NM_205863
PARD3B


par-3 partitioning defective 3 homolog B (C. elegans)


chr3_-_49851356 0.104 NM_003335
UBA7
ubiquitin-like modifier activating enzyme 7
chr5_+_137774632 0.104 NM_016606
REEP2
receptor accessory protein 2
chr5_+_137774897 0.103 REEP2
receptor accessory protein 2
chr19_-_6375859 0.103 NM_004158
PSPN
persephin
chr17_-_7017971 0.103 ASGR2
asialoglycoprotein receptor 2
chr1_+_53925482 0.102 DMRTB1
DMRT-like family B with proline-rich C-terminal, 1
chr14_+_24605393 0.102 PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr6_+_168841873 0.102 SMOC2
SPARC related modular calcium binding 2
chr15_+_81489218 0.102 NM_001172128
IL16
interleukin 16
chr19_+_36359346 0.102 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr18_-_56940616 0.101 NM_013435
RAX
retina and anterior neural fold homeobox
chr3_-_49851217 0.101 UBA7
ubiquitin-like modifier activating enzyme 7
chr7_+_44788453 0.101 NM_031449
ZMIZ2
zinc finger, MIZ-type containing 2
chr11_+_1886394 0.100 NM_001242932
LSP1
lymphocyte-specific protein 1
chr7_-_150864866 0.099 NM_001098834
GBX1
gastrulation brain homeobox 1
chr22_-_31885512 0.099 NM_001164501
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr8_-_124553448 0.099 NM_001242463
NM_058229
FBXO32

F-box protein 32

chr3_-_9920633 0.098 NM_022094
CIDEC
cell death-inducing DFFA-like effector c
chr6_-_6007632 0.098 NM_016588
NRN1
neuritin 1
chr17_+_5972425 0.098 WSCD1
WSC domain containing 1
chr3_-_9920471 0.098 NM_001199623
CIDEC
cell death-inducing DFFA-like effector c
chr6_+_31683084 0.097 NM_021246
LY6G6D
lymphocyte antigen 6 complex, locus G6D
chr3_+_105085740 0.097 ALCAM
activated leukocyte cell adhesion molecule
chr5_-_159739482 0.097 NM_024565
CCNJL
cyclin J-like
chr3_+_8543539 0.097 LMCD1
LIM and cysteine-rich domains 1
chr5_+_139027955 0.096 CXXC5
CXXC finger protein 5
chr5_+_139027907 0.096 CXXC5
CXXC finger protein 5
chr10_-_15413054 0.096 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr8_+_104383785 0.096 NM_138455
CTHRC1
collagen triple helix repeat containing 1
chr5_+_96271086 0.096 LNPEP
leucyl/cystinyl aminopeptidase
chr12_-_52585686 0.096 NM_001081492
NM_182507
KRT80

keratin 80

chrX_-_13956530 0.095 GPM6B
glycoprotein M6B
chr6_+_35182182 0.095 NM_152753
SCUBE3
signal peptide, CUB domain, EGF-like 3
chr6_+_35181721 0.095 SCUBE3
signal peptide, CUB domain, EGF-like 3
chr19_+_18111923 0.094 NM_001025604
ARRDC2
arrestin domain containing 2
chr19_-_11591439 0.094 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr3_+_170136652 0.094 NM_005602
CLDN11
claudin 11
chr5_+_149569810 0.094 SLC6A7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr19_+_8478181 0.094 NM_001005415
NM_001005416
NM_016496
MARCH2


membrane-associated ring finger (C3HC4) 2


chr12_-_7245048 0.094 C1R
complement component 1, r subcomponent
chr8_-_57123827 0.094 PLAG1
pleiomorphic adenoma gene 1
chr1_+_210501595 0.094 NM_001122834
NM_001170564
HHAT

hedgehog acyltransferase

chr4_-_2366530 0.093 NM_001172659
NM_001172660
ZFYVE28

zinc finger, FYVE domain containing 28

chr2_+_109745996 0.093 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr19_-_46285752 0.092 NM_001081560
NM_001081562
NM_004409
DMPK


dystrophia myotonica-protein kinase


chrX_-_19140581 0.092 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr1_-_183387501 0.092 NM_015039
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr13_+_102104941 0.092 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr1_+_77747602 0.091 NM_174858
AK5
adenylate kinase 5
chr17_+_77030471 0.091 NM_198593
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_-_72542148 0.091 CD300C
CD300c molecule
chrX_-_152939256 0.091 PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chrX_-_100306859 0.091 TRMT2B
TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae)
chr21_-_45079327 0.090 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chr3_+_69788562 0.090 NM_198159
MITF
microphthalmia-associated transcription factor
chr1_+_53925071 0.090 NM_033067
DMRTB1
DMRT-like family B with proline-rich C-terminal, 1
chr4_-_16085593 0.090 NM_001145847
NM_001145848
PROM1

prominin 1

chr10_-_13276327 0.089 NM_145314
UCMA
upper zone of growth plate and cartilage matrix associated
chr4_-_129208964 0.089 PGRMC2
progesterone receptor membrane component 2
chr1_-_26232890 0.089 NM_001145454
NM_005563
STMN1

stathmin 1

chr1_+_23695441 0.089 C1orf213
chromosome 1 open reading frame 213
chr13_+_32605436 0.088 NM_023037
FRY
furry homolog (Drosophila)
chr4_-_57976550 0.088 NM_001253835
NM_001553
IGFBP7

insulin-like growth factor binding protein 7

chrX_-_15872882 0.088 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr11_-_1785087 0.088 CTSD
cathepsin D
chr5_-_126366439 0.088 NM_178450
MARCH3
membrane-associated ring finger (C3HC4) 3
chr17_+_78194090 0.088 NM_001166347
NM_001166348
NM_001166349
NM_173626
SLC26A11



solute carrier family 26, member 11



chr19_+_50016490 0.088 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr14_-_61115906 0.087 NM_005982
SIX1
SIX homeobox 1
chr9_-_115652961 0.087 NM_033051
SLC46A2
solute carrier family 46, member 2
chr6_+_26501448 0.087 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.28 3.43e-08 GO:0048856 anatomical structure development
1.27 2.73e-06 GO:0048731 system development
1.23 3.19e-06 GO:0032502 developmental process
1.23 9.11e-06 GO:0007275 multicellular organismal development
1.29 1.77e-04 GO:0030154 cell differentiation
1.28 3.28e-04 GO:0048869 cellular developmental process
1.34 3.72e-04 GO:0007399 nervous system development
1.44 4.80e-04 GO:0022008 neurogenesis
1.31 1.46e-03 GO:0023051 regulation of signaling
1.43 2.41e-03 GO:0048699 generation of neurons
1.76 3.05e-03 GO:0061061 muscle structure development
1.40 5.48e-03 GO:0048468 cell development
1.10 8.11e-03 GO:0065007 biological regulation
1.88 8.22e-03 GO:0007517 muscle organ development
1.11 1.16e-02 GO:0050789 regulation of biological process
1.29 1.18e-02 GO:0009653 anatomical structure morphogenesis
1.33 3.72e-02 GO:0010646 regulation of cell communication

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 2.06e-03 GO:0005783 endoplasmic reticulum
1.27 3.37e-03 GO:0012505 endomembrane system
1.22 7.10e-03 GO:0031090 organelle membrane
1.40 1.17e-02 GO:0005789 endoplasmic reticulum membrane
1.39 1.60e-02 GO:0042175 nuclear membrane-endoplasmic reticulum network
4.75 1.76e-02 GO:0031105 septin complex
4.75 1.76e-02 GO:0032156 septin cytoskeleton
1.36 1.97e-02 GO:0044432 endoplasmic reticulum part

Nothing significant found in function category.