Motif ID: NFATC1..3.p2

Z-value: 0.732


Transcription factors associated with NFATC1..3.p2:

Gene SymbolEntrez IDGene Name
NFATC1 4772 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 4773 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 4775 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFATC3chr16_+_68119211-0.874.6e-03Click!
NFATC1chr18_+_77155966-0.734.0e-02Click!
NFATC2chr20_-_50179338-0.705.1e-02Click!


Activity profile for motif NFATC1..3.p2.

activity profile for motif NFATC1..3.p2


Sorted Z-values histogram for motif NFATC1..3.p2

Sorted Z-values for motif NFATC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFATC1..3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_189839132 1.369 COL3A1
collagen, type III, alpha 1
chr2_-_238322840 1.301 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr2_-_238322770 1.232 COL6A3
collagen, type VI, alpha 3
chr2_-_238322815 1.228 COL6A3
collagen, type VI, alpha 3
chr2_+_189839078 1.222 NM_000090
COL3A1
collagen, type III, alpha 1
chr12_-_91573264 1.038 NM_133503
DCN
decorin
chr2_+_189839113 1.010 COL3A1
collagen, type III, alpha 1
chr12_+_13349716 0.971 EMP1
epithelial membrane protein 1
chr1_-_169599349 0.713 NM_003005
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr12_-_11286842 0.552 NM_001097643
TAS2R30
taste receptor, type 2, member 30
chr13_+_102104941 0.543 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr12_+_13349720 0.506 EMP1
epithelial membrane protein 1
chr2_-_127963342 0.497 NM_001001665
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr3_-_112359863 0.484 CCDC80
coiled-coil domain containing 80
chr4_+_74606222 0.475 NM_000584
IL8
interleukin 8
chr13_-_24007822 0.463 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr4_-_70626429 0.460 NM_014465
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr7_+_100199881 0.456 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr3_-_112359962 0.451 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr14_-_92413738 0.422 FBLN5
fibulin 5
chr1_+_163038934 0.421 NM_001113381
RGS4
regulator of G-protein signaling 4
chr10_+_69869249 0.410 NM_032578
MYPN
myopalladin
chr5_-_150537335 0.403 NM_001155
ANXA6
annexin A6
chr11_+_65271145 0.402


chr7_-_131241321 0.400 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr13_-_38172862 0.399 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr3_+_157154579 0.397 NM_002852
PTX3
pentraxin 3, long
chr17_-_29648631 0.397 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr5_-_172755418 0.396 STC2
stanniocalcin 2
chr3_+_45067750 0.389 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr12_+_13349601 0.388 NM_001423
EMP1
epithelial membrane protein 1
chr15_-_55652777 0.385 CCPG1
cell cycle progression 1
chr1_+_159175048 0.369 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr7_+_23286384 0.364 GPNMB
glycoprotein (transmembrane) nmb
chr1_-_151431648 0.355 POGZ
pogo transposable element with ZNF domain
chr7_+_93551015 0.354 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr7_+_23286390 0.350 GPNMB
glycoprotein (transmembrane) nmb
chr19_+_55315065 0.345 NM_001080770
NM_001080772
NM_002255
KIR2DL4


killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4


chr1_-_57045235 0.340 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr3_+_69812961 0.328 NM_006722
MITF
microphthalmia-associated transcription factor
chr8_-_13372183 0.328 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr5_-_78282356 0.327 NM_000046
ARSB
arylsulfatase B
chr12_-_10151689 0.324 NM_001099431
NM_016509
CLEC1B

C-type lectin domain family 1, member B

chr2_-_97405799 0.323 NM_001142292
NM_030805
LMAN2L

lectin, mannose-binding 2-like

chr3_+_186560462 0.323 NM_001177800
NM_004797
ADIPOQ

adiponectin, C1Q and collagen domain containing

chr1_-_150780705 0.321 NM_000396
CTSK
cathepsin K
chr3_+_186560478 0.320 ADIPOQ
adiponectin, C1Q and collagen domain containing
chr5_+_140602914 0.316 NM_018934
PCDHB14
protocadherin beta 14
chr2_-_192711923 0.316 NM_004657
SDPR
serum deprivation response
chr2_-_174767282 0.313


chr7_+_94024201 0.312 COL1A2
collagen, type I, alpha 2
chr1_+_45274153 0.309 NM_001136537
BTBD19
BTB (POZ) domain containing 19
chr12_+_56075329 0.307 NM_152637
METTL7B
methyltransferase like 7B
chr5_-_111093792 0.304 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr1_+_159173802 0.304 NM_002036
DARC
Duffy blood group, chemokine receptor
chr1_+_162602308 0.293 DDR2
discoidin domain receptor tyrosine kinase 2
chr11_+_113775517 0.293 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr7_+_23286386 0.293 GPNMB
glycoprotein (transmembrane) nmb
chrX_+_152760452 0.289 BGN
biglycan
chr8_+_98703361 0.287 MTDH
metadherin
chr11_-_5462782 0.287 NM_001005288
OR51I1
olfactory receptor, family 51, subfamily I, member 1
chr2_-_200329810 0.286 NM_001172517
SATB2
SATB homeobox 2
chr6_-_128841432 0.286 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr19_+_41725277 0.285 AXL
AXL receptor tyrosine kinase
chr8_+_17433941 0.285 NM_006207
PDGFRL
platelet-derived growth factor receptor-like
chr3_-_178984789 0.284 NM_001163677
NM_171828
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr7_+_48211054 0.282 NM_152701
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr11_-_118550354 0.282 NM_007180
TREH
trehalase (brush-border membrane glycoprotein)
chr9_+_120466625 0.281 TLR4
toll-like receptor 4
chr12_+_56075418 0.279 METTL7B
methyltransferase like 7B
chrX_+_152760346 0.277 NM_001711
BGN
biglycan
chr1_+_162602198 0.275 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr2_-_97405775 0.272 LMAN2L
lectin, mannose-binding 2-like
chr3_-_156878481 0.270 NM_020307
CCNL1
cyclin L1
chr9_-_95186559 0.269 NM_005014
OMD
osteomodulin
chr3_-_195310985 0.269 NM_001647
APOD
apolipoprotein D
chr20_+_12989616 0.267 NM_018327
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr6_-_169653922 0.265 THBS2
thrombospondin 2
chr10_+_31610063 0.264 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr17_-_63822660 0.261 NM_001037325
CEP112
centrosomal protein 112kDa
chr10_+_124320180 0.258 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr3_-_112358510 0.257 CCDC80
coiled-coil domain containing 80
chr1_+_174843523 0.255 NM_001243763
RABGAP1L
RAB GTPase activating protein 1-like
chr5_+_92918924 0.254 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr3_-_112358758 0.251 CCDC80
coiled-coil domain containing 80
chr8_+_70405080 0.250 SULF1
sulfatase 1
chr17_-_15164043 0.249 NM_153322
PMP22
peripheral myelin protein 22
chr3_+_12392993 0.247 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr8_+_17822093 0.245 PCM1
pericentriolar material 1
chr7_+_120629444 0.241 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr2_-_202563353 0.240 NM_033066
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr5_+_140809957 0.238 PCDHGA12
protocadherin gamma subfamily A, 12
chr11_+_131240370 0.238 NM_001048209
NTM
neurotrimin
chr2_-_188419049 0.237 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr7_+_23286277 0.236 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr12_-_56106061 0.236 NM_001144997
ITGA7
integrin, alpha 7
chr4_-_76928601 0.233 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr1_+_163041694 0.231 NM_001113380
RGS4
regulator of G-protein signaling 4
chr13_-_67804432 0.226 NM_020403
NM_203487
PCDH9

protocadherin 9

chr13_-_34250899 0.226 NM_001243476
STARD13
StAR-related lipid transfer (START) domain containing 13
chrX_-_132162297 0.224 NM_031907
USP26
ubiquitin specific peptidase 26
chr21_+_39628663 0.223 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr11_-_67141647 0.222 NM_001166212
CLCF1
cardiotrophin-like cytokine factor 1
chr4_+_70916158 0.221 NM_002159
HTN1
histatin 1
chr17_-_42908178 0.220 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr2_-_188419185 0.220 NM_001032281
NM_006287
TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr7_+_104681378 0.219 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr16_+_2039945 0.219 NM_004209
SYNGR3
synaptogyrin 3
chr3_-_112359277 0.219 CCDC80
coiled-coil domain containing 80
chr2_+_113735595 0.218 NM_019618
IL36G
interleukin 36, gamma
chr6_+_30973728 0.218 NM_001198815
MUC22
mucin 22
chr8_+_97506071 0.215 SDC2
syndecan 2
chr2_-_190044330 0.205 NM_000393
COL5A2
collagen, type V, alpha 2
chr8_+_70405027 0.204 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr12_-_91576579 0.204 DCN
decorin
chr21_+_39628869 0.203 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_147425566 0.202 NM_001097616
GPR89C
G protein-coupled receptor 89C
chr17_-_67138013 0.201 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr15_+_32933869 0.199 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr7_+_80267782 0.199 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr5_+_59784004 0.198 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr5_+_156820161 0.196 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr8_+_97506141 0.196 SDC2
syndecan 2
chr17_-_39216343 0.195 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr3_-_112359251 0.195 CCDC80
coiled-coil domain containing 80
chr9_-_27005649 0.195 NM_022901
LRRC19
leucine rich repeat containing 19
chr7_+_23286401 0.194 GPNMB
glycoprotein (transmembrane) nmb
chr3_-_112359547 0.194 CCDC80
coiled-coil domain containing 80
chr5_+_140734767 0.193 NM_018917
NM_032053
PCDHGA4

protocadherin gamma subfamily A, 4

chr9_+_79115548 0.192 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr12_-_91576805 0.192 NM_001920
DCN
decorin
chr2_+_152214105 0.191 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_-_146833150 0.190 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr5_+_118965253 0.188 NM_001163991
NM_182761
FAM170A

family with sequence similarity 170, member A

chr10_+_91087601 0.187 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr8_+_97506020 0.187 SDC2
syndecan 2
chr9_+_91605777 0.186 NM_001001938
NM_001142413
C9orf47

chromosome 9 open reading frame 47

chr10_-_79789164 0.184 POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr12_-_29937691 0.182 NM_175861
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr1_-_9117554 0.182 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr17_-_18177716 0.181 TOP3A
topoisomerase (DNA) III alpha
chr5_-_64777703 0.180 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr12_-_90049818 0.180 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr12_-_47219734 0.180 NM_001143824
NM_018018
SLC38A4

solute carrier family 38, member 4

chr5_+_140739589 0.180 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr3_-_112359565 0.179 CCDC80
coiled-coil domain containing 80
chr3_-_112359660 0.179 CCDC80
coiled-coil domain containing 80
chr12_-_15038724 0.179 NM_000900
NM_001190839
MGP

matrix Gla protein

chr10_-_79789290 0.177 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr11_+_65266642 0.177


chr4_+_71200670 0.176 NM_033122
CABS1
calcium-binding protein, spermatid-specific 1
chr6_+_163148163 0.175 NM_001080378
NM_152410
PACRG

PARK2 co-regulated

chr6_+_47666288 0.174 NM_153838
GPR115
G protein-coupled receptor 115
chr21_+_26934440 0.174 MIR155HG
MIR155 host gene (non-protein coding)
chrX_-_19688991 0.174 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr1_-_157670280 0.173 NM_052939
FCRL3
Fc receptor-like 3
chr5_-_111091947 0.172 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr11_+_15133969 0.171 NM_001031853
INSC
inscuteable homolog (Drosophila)
chr3_+_69134057 0.170 NM_006407
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr1_-_161193190 0.169 APOA2
apolipoprotein A-II
chr2_+_204801453 0.168 NM_012092
ICOS
inducible T-cell co-stimulator
chr9_-_91793375 0.168 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr3_-_112359443 0.168 CCDC80
coiled-coil domain containing 80
chr3_-_195310770 0.167 APOD
apolipoprotein D
chr9_+_131388167 0.166 SPTAN1
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr5_+_71502700 0.166 MAP1B
microtubule-associated protein 1B
chr17_-_17740288 0.165 SREBF1
sterol regulatory element binding transcription factor 1
chr1_+_78354199 0.165 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr1_+_222791151 0.164 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr9_+_5510544 0.164 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr5_+_140729723 0.163 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr2_-_47797469 0.163 NM_022055
KCNK12
potassium channel, subfamily K, member 12
chr17_-_80291610 0.162 SECTM1
secreted and transmembrane 1
chrX_+_86772714 0.162 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr17_-_80291639 0.161 SECTM1
secreted and transmembrane 1
chr6_+_39760772 0.161 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr13_-_49110117 0.160 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr12_+_2162703 0.160 CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr20_-_13971256 0.159 NM_025229
SEL1L2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr5_+_304290 0.159 NM_001242412
NM_020731
AHRR

aryl-hydrocarbon receptor repressor

chr9_+_91606349 0.155 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chr1_-_203320249 0.154


chr5_-_121413967 0.154 LOX
lysyl oxidase
chr5_+_75699003 0.153 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr6_-_38563763 0.153 NM_001172418
NM_152733
BTBD9

BTB (POZ) domain containing 9

chrX_-_70331297 0.153 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr1_+_185703470 0.153 NM_031935
HMCN1
hemicentin 1
chr5_-_73937248 0.152 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr3_+_46619075 0.152 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr5_+_110407389 0.151 NM_033035
TSLP
thymic stromal lymphopoietin
chr17_-_67311773 0.150 NM_018672
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr14_-_107218786 0.150 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr12_-_81991959 0.150 NM_001220477
NM_001220478
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr1_+_145883867 0.150 NM_001097616
GPR89C
G protein-coupled receptor 89C
chr5_+_180794268 0.149 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr15_-_45480160 0.147 SHF
Src homology 2 domain containing F
chr5_-_176935877 0.147 DOK3
docking protein 3
chr2_+_197504277 0.147 NM_001080539
CCDC150
coiled-coil domain containing 150
chr3_+_45927995 0.147 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr5_+_140753480 0.145 NM_018919
NM_032086
PCDHGA6

protocadherin gamma subfamily A, 6


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.56 1.02e-05 GO:0009611 response to wounding
1.58 6.06e-05 GO:0007155 cell adhesion
1.58 6.06e-05 GO:0022610 biological adhesion
1.78 1.38e-02 GO:0006954 inflammatory response
1.75 1.65e-02 GO:0016337 cell-cell adhesion
1.52 1.81e-02 GO:0042060 wound healing
2.05 3.24e-02 GO:0043062 extracellular structure organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.58 6.51e-09 GO:0044421 extracellular region part
1.37 9.48e-08 GO:0005576 extracellular region
1.57 2.47e-06 GO:0005615 extracellular space
1.75 8.99e-04 GO:0005578 proteinaceous extracellular matrix
3.45 1.54e-03 GO:0005581 collagen
1.66 2.19e-03 GO:0031012 extracellular matrix
5.65 4.24e-03 GO:0005583 fibrillar collagen
1.11 1.23e-02 GO:0044425 membrane part
1.15 1.28e-02 GO:0071944 cell periphery
1.15 1.41e-02 GO:0005886 plasma membrane
1.22 1.70e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.71 4.27e-02 GO:0001608 nucleotide receptor activity, G-protein coupled
3.71 4.27e-02 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled