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Motif ID: NFE2.p2

Z-value: 0.566

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr18_+_21452981	0.830	NM_000227 NM_001127718	LAMA3	laminin, alpha 3
chr1_+_183155173	0.546	NM_005562 NM_018891	LAMC2	laminin, gamma 2
chr1_+_183155361	0.483		LAMC2	laminin, gamma 2
chr1_+_183155393	0.398		LAMC2	laminin, gamma 2
chr12_+_78225068	0.390	NM_014903	NAV3	neuron navigator 3
chr4_+_41258941	0.375		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr11_-_102668822	0.287		MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr11_-_102668892	0.273	NM_001145938 NM_002421	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr11_+_62649160	0.237		SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr4_-_39033981	0.218	NM_024943	TMEM156	transmembrane protein 156
chr7_+_116312412	0.217	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr8_-_145025043	0.203	NM_201380	PLEC	plectin
chr6_+_47624222	0.198	NM_153839	GPR111	G protein-coupled receptor 111
chr1_+_35246789	0.188	NM_024009	GJB3	gap junction protein, beta 3, 31kDa
chr8_-_145016691	0.176	NM_201383	PLEC	plectin
chr17_-_39280377	0.173	NM_031854	KRTAP4-12	keratin associated protein 4-12
chr11_-_65667809	0.171		FOSL1	FOS-like antigen 1
chrX_+_133371076	0.169	NM_001101357	CCDC160	coiled-coil domain containing 160
chr20_+_44637539	0.169	NM_004994	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr19_-_36004553	0.158	NM_001126056 NM_001126057 NM_001126058 NM_001190347 NM_001190348 NM_001190349 NM_033317	DMKN	dermokine
chr16_+_57662301	0.157	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr7_+_26331611	0.156		SNX10	sorting nexin 10
chr4_-_139163222	0.155	NM_014331	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr10_-_90611675	0.153	NM_144590	ANKRD22	ankyrin repeat domain 22
chr9_-_86322593	0.152		UBQLN1	ubiquilin 1
chr7_+_26331493	0.148	NM_001199835 NM_013322	SNX10	sorting nexin 10
chr11_-_65667860	0.148	NM_005438	FOSL1	FOS-like antigen 1
chr11_-_65667858	0.147		FOSL1	FOS-like antigen 1
chr4_-_36245893	0.145	NM_015230	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_+_84457256	0.141		AGPAT9	1-acylglycerol-3-phosphate O-acyltransferase 9
chr17_+_48610077	0.138		EPN3	epsin 3
chr1_+_32043745	0.135	NM_001204415	TINAGL1	tubulointerstitial nephritis antigen-like 1
chr16_-_30124829	0.133	NM_024307	GDPD3	glycerophosphodiester phosphodiesterase domain containing 3
chr3_+_184038050	0.133	NM_004953	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr6_-_30685457	0.126	NM_014641	MDC1	mediator of DNA-damage checkpoint 1
chr1_-_225616556	0.125	NM_194442	LBR	lamin B receptor
chr6_-_30684851	0.124		MDC1	mediator of DNA-damage checkpoint 1
chr3_+_184038445	0.123		EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr18_+_55888838	0.120		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr9_-_117880411	0.120	NM_002160	TNC	tenascin C
chr1_+_81771844	0.120		LPHN2	latrophilin 2
chr17_-_39675078	0.116	NM_002275	KRT15	keratin 15
chr18_+_61442611	0.116	NM_003784	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_-_6662681	0.115		KLHL21	kelch-like 21 (Drosophila)
chr6_+_31895201	0.114	NM_000063 NM_001145903	C2	complement component 2
chr15_+_40532034	0.114	NM_020168	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr15_+_40531236	0.113		PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr14_-_21572374	0.113
chr18_+_55888799	0.113		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr14_+_73525267	0.111		RBM25	RNA binding motif protein 25
chr14_-_24777184	0.109		CIDEB	cell death-inducing DFFA-like effector b
chr11_+_64323089	0.107	NM_018484	SLC22A11	solute carrier family 22 (organic anion/urate transporter), member 11
chr14_-_24777153	0.107		CIDEB	cell death-inducing DFFA-like effector b
chr1_+_209602164	0.106	NM_001104548	MIR205HG	MIR205 host gene (non-protein coding)
chr14_+_73525187	0.106	NM_021239	RBM25	RNA binding motif protein 25
chr6_+_44195008	0.105		SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chrX_-_19817854	0.104		SH3KBP1	SH3-domain kinase binding protein 1
chr4_+_84457390	0.104	NM_032717	AGPAT9	1-acylglycerol-3-phosphate O-acyltransferase 9
chr3_-_98241722	0.104		CLDND1	claudin domain containing 1
chr19_+_7953380	0.104	NM_025061	LRRC8E	leucine rich repeat containing 8 family, member E
chr6_-_84140854	0.103	NM_002395	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr6_-_84140758	0.102		ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr14_+_73525232	0.101		RBM25	RNA binding motif protein 25
chr20_+_6748744	0.100	NM_001200	BMP2	bone morphogenetic protein 2
chr1_-_153588789	0.099	NM_020672	S100A14	S100 calcium binding protein A14
chr17_+_47288068	0.097		ABI3	ABI family, member 3
chr6_-_138428477	0.097	NM_022121	PERP	PERP, TP53 apoptosis effector
chr9_-_86322861	0.097		UBQLN1	ubiquilin 1
chr4_-_89080010	0.096	NM_004827	ABCG2	ATP-binding cassette, sub-family G (WHITE), member 2
chr1_-_94374986	0.096	NM_002061	GCLM	glutamate-cysteine ligase, modifier subunit
chr2_+_109335906	0.095	NM_006267	RANBP2	RAN binding protein 2
chr1_-_94374949	0.095		GCLM	glutamate-cysteine ligase, modifier subunit
chr14_+_103801160	0.095	NM_183004	EIF5	eukaryotic translation initiation factor 5
chr9_+_35673852	0.094	NM_001216	CA9	carbonic anhydrase IX
chr16_+_82068830	0.094	NM_002153	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr11_+_394199	0.093	NM_007183	PKP3	plakophilin 3
chr14_+_73525302	0.093		RBM25	RNA binding motif protein 25
chr6_+_32121228	0.093	NM_138717	PPT2	palmitoyl-protein thioesterase 2
chr6_-_84140744	0.092		ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr11_-_58343308	0.092	NM_004811	LPXN	leupaxin
chr11_-_9025531	0.092	NM_020645	NRIP3	nuclear receptor interacting protein 3
chr10_+_115312777	0.092	NM_004132	HABP2	hyaluronan binding protein 2
chr17_+_7482804	0.092	NM_001251 NM_001040059	CD68	CD68 molecule
chrX_-_153285262	0.091		IRAK1	interleukin-1 receptor-associated kinase 1
chr22_-_27013959	0.090	NM_001887	CRYBB1	crystallin, beta B1
chr10_-_119134737	0.090	NM_173791	PDZD8	PDZ domain containing 8
chr8_-_145013628	0.090	NM_201384	PLEC	plectin
chr18_+_61554938	0.090	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr10_-_71892514	0.089		AIFM2	apoptosis-inducing factor, mitochondrion-associated, 2
chr20_-_30457800	0.089	NM_001012644	DUSP15	dual specificity phosphatase 15
chr9_+_140172273	0.088	NM_017723	C9orf167	chromosome 9 open reading frame 167
chr19_-_6670598	0.088	NM_003807 NM_172014	TNFSF14	tumor necrosis factor (ligand) superfamily, member 14
chr12_-_54813002	0.088		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr12_+_110719143	0.088		ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr11_+_394238	0.088		PKP3	plakophilin 3
chr9_-_86322844	0.087		UBQLN1	ubiquilin 1
chr1_+_40735749	0.087		ZMPSTE24	zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr17_+_7482938	0.087		CD68	CD68 molecule
chr10_-_71892596	0.086	NM_001198696 NM_032797	AIFM2	apoptosis-inducing factor, mitochondrion-associated, 2
chr9_-_86323117	0.086	NM_013438 NM_053067	UBQLN1	ubiquilin 1
chr10_-_6019880	0.085	NM_001243539	IL15RA	interleukin 15 receptor, alpha
chr17_-_38721701	0.085	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chr1_-_207205996	0.085	NM_001083924 NM_023938	C1orf116	chromosome 1 open reading frame 116
chr19_+_1248548	0.084	NM_177401	MIDN	midnolin
chr21_-_36421578	0.084		RUNX1	runt-related transcription factor 1
chr14_-_94854910	0.084		SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr22_-_27014037	0.084		CRYBB1	crystallin, beta B1
chr3_-_149095333	0.084		TM4SF1	transmembrane 4 L six family member 1
chr2_-_142889269	0.083	NM_018557	LRP1B	low density lipoprotein receptor-related protein 1B
chr11_+_20620945	0.083	NM_004211	SLC6A5	solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr14_-_105436817	0.083		AHNAK2	AHNAK nucleoprotein 2
chr3_-_149095413	0.083		TM4SF1	transmembrane 4 L six family member 1
chr8_-_26724748	0.083		ADRA1A	adrenergic, alpha-1A-, receptor
chr1_-_6662898	0.083	NM_014851	KLHL21	kelch-like 21 (Drosophila)
chr1_+_160160284	0.082	NM_001231	CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)
chr15_+_86220267	0.081	NM_144767	AKAP13	A kinase (PRKA) anchor protein 13
chr1_+_223889253	0.081	NM_001146068	CAPN2	calpain 2, (m/II) large subunit
chr8_+_24771268	0.081	NM_005382	NEFM	neurofilament, medium polypeptide
chr15_+_41136178	0.081	NM_003710 NM_181642	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr9_+_140135698	0.081	NM_006088	TUBB4B	tubulin, beta 4B class IVb
chr14_-_94855120	0.081	NM_000295	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr17_-_29641087	0.081		EVI2B	ecotropic viral integration site 2B
chr6_-_35888889	0.080		SRPK1	SRSF protein kinase 1
chr6_+_34206567	0.080	NM_145905	HMGA1	high mobility group AT-hook 1
chr9_+_140135738	0.080		TUBB4B	tubulin, beta 4B class IVb
chr2_+_133174146	0.080	NM_001508	GPR39	G protein-coupled receptor 39
chr6_-_35888816	0.080		SRPK1	SRSF protein kinase 1
chrX_-_19688991	0.079	NM_001184960	SH3KBP1	SH3-domain kinase binding protein 1
chr18_-_47376156	0.079		MYO5B	myosin VB
chr17_+_30771532	0.079		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr17_-_79881304	0.078	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr6_-_35888937	0.078	NM_003137	SRPK1	SRSF protein kinase 1
chr1_-_8931634	0.078	NM_001201483	ENO1	enolase 1, (alpha)
chr17_-_38657814	0.078	NM_032865	TNS4	tensin 4
chr3_-_149095458	0.078		TM4SF1	transmembrane 4 L six family member 1
chr8_+_24771276	0.078		NEFM	neurofilament, medium polypeptide
chr7_+_73245192	0.078	NM_001305	CLDN4	claudin 4
chr15_+_89182038	0.077	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr11_+_35160385	0.077	NM_000610 NM_001001389 NM_001001390 NM_001001391 NM_001001392 NM_001202555 NM_001202556 NM_001202557	CD44	CD44 molecule (Indian blood group)
chr17_+_30771522	0.075		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr9_-_86322870	0.075		UBQLN1	ubiquilin 1
chr8_+_32504250	0.075	NM_013959	NRG1	neuregulin 1
chr17_+_79651035	0.074		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr9_-_123688352	0.074		TRAF1	TNF receptor-associated factor 1
chrX_-_153285334	0.074	NM_001025242 NM_001025243 NM_001569	IRAK1	interleukin-1 receptor-associated kinase 1
chr17_-_10741398	0.073	NM_001101387	PIRT	phosphoinositide-interacting regulator of transient receptor potential channels
chr17_+_30771485	0.073		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr11_-_71781091	0.072		NUMA1	nuclear mitotic apparatus protein 1
chr4_+_120056938	0.072	NM_016599	MYOZ2	myozenin 2
chr9_+_140135742	0.072		TUBB4B	tubulin, beta 4B class IVb
chr17_+_30771494	0.072	NM_002815	PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr14_+_58711599	0.072		PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr12_-_51403028	0.071	NM_001174130	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr16_+_82068958	0.071		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr12_-_54812936	0.071		ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr11_+_118958696	0.070	NM_001024382	HMBS	hydroxymethylbilane synthase
chr12_-_108991893	0.070	NM_181724	TMEM119	transmembrane protein 119
chr2_+_120189342	0.070	NM_183240	TMEM37	transmembrane protein 37
chr2_+_172864803	0.070	NM_199227	METAP1D	methionyl aminopeptidase type 1D (mitochondrial)
chr7_-_92462637	0.069		CDK6	cyclin-dependent kinase 6
chr17_-_34266359	0.068	NM_020426	LYZL6	lysozyme-like 6
chr15_+_91260575	0.068	NM_000057	BLM	Bloom syndrome, RecQ helicase-like
chr11_+_35160666	0.068		CD44	CD44 molecule (Indian blood group)
chr8_+_22210311	0.068		PIWIL2	piwi-like 2 (Drosophila)
chr4_-_26491888	0.068	NM_000730	CCKAR	cholecystokinin A receptor
chr18_+_61254533	0.067	NM_012397	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr7_+_112063131	0.067	NM_001007245 NM_001197080	IFRD1	interferon-related developmental regulator 1
chr3_-_108308221	0.067		KIAA1524	KIAA1524
chr1_+_32083286	0.067	NM_001525	HCRTR1	hypocretin (orexin) receptor 1
chr17_+_7482980	0.067		CD68	CD68 molecule
chr14_+_103800678	0.067		EIF5	eukaryotic translation initiation factor 5
chr4_-_80329354	0.066	NM_033214	GK2	glycerol kinase 2
chr17_-_38911524	0.066	NM_181534	KRT25	keratin 25
chr6_+_1611544	0.066		FOXC1	forkhead box C1
chr10_-_6019454	0.066	NM_002189 NM_172200	IL15RA	interleukin 15 receptor, alpha
chrX_-_19817907	0.066	NM_001024666	SH3KBP1	SH3-domain kinase binding protein 1
chr6_+_44214786	0.066	NM_007355	HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1
chr17_+_18625335	0.065	NM_001037330	TRIM16L	tripartite motif containing 16-like
chr1_+_19638739	0.065	NM_001040125 NM_001040126 NM_017765	PQLC2	PQ loop repeat containing 2
chr3_-_108308460	0.064	NM_020890	KIAA1524	KIAA1524
chr17_-_65362635	0.064		PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr16_+_31404596	0.064	NM_005353	ITGAD	integrin, alpha D
chr5_+_145317297	0.064		SH3RF2	SH3 domain containing ring finger 2
chr17_-_39216343	0.063	NM_001165252	LOC730755	keratin associated protein 2-4-like
chr12_-_54813010	0.063	NM_002205	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr12_-_51402988	0.063		SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr9_-_86322854	0.063		UBQLN1	ubiquilin 1
chr19_+_39833132	0.062		SAMD4B	sterile alpha motif domain containing 4B
chr4_-_101111606	0.062	NM_145244	DDIT4L	DNA-damage-inducible transcript 4-like
chr11_+_10476665	0.062	NM_001025389	AMPD3	adenosine monophosphate deaminase 3
chr2_+_47596286	0.061	NM_002354	EPCAM	epithelial cell adhesion molecule
chr8_+_125487193	0.061		RNF139	ring finger protein 139
chr5_-_16738346	0.060		MYO10	myosin X
chr5_+_61714710	0.059	NM_001134779	IPO11	importin 11
chr2_+_233562031	0.059		GIGYF2	GRB10 interacting GYF protein 2
chr4_+_36283243	0.059	NM_001136536	DTHD1	death domain containing 1
chr19_-_44285012	0.059		KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr21_-_36421586	0.059	NM_001754	RUNX1	runt-related transcription factor 1
chr5_-_137911005	0.058		HSPA9	heat shock 70kDa protein 9 (mortalin)
chr12_-_53343607	0.058		KRT8	keratin 8

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.42	3.49e-03	GO:0006950	response to stress
2.46	4.04e-03	GO:0048545	response to steroid hormone stimulus
1.44	4.28e-03	GO:0042221	response to chemical stimulus
1.74	5.75e-03	GO:0051704	multi-organism process
1.58	1.22e-02	GO:0010033	response to organic substance
1.59	1.44e-02	GO:0002376	immune system process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.76	6.74e-04	GO:0005626	insoluble fraction
1.74	1.55e-03	GO:0005624	membrane fraction
1.42	1.63e-03	GO:0044459	plasma membrane part
1.61	1.99e-03	GO:0000267	cell fraction
3.92	6.67e-03	GO:0000502	proteasome complex
2.42	1.30e-02	GO:0005911	cell-cell junction
6.33	2.21e-02	GO:0001533	cornified envelope
1.74	2.47e-02	GO:0030054	cell junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.75	4.87e-03	GO:0019899	enzyme binding
1.17	1.23e-02	GO:0005515	protein binding
2.43	4.04e-02	GO:0005126	cytokine receptor binding