Motif ID: NFE2L2.p2

Z-value: 1.011


Transcription factors associated with NFE2L2.p2:

Gene SymbolEntrez IDGene Name
NFE2L2 4780 nuclear factor (erythroid-derived 2)-like 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2L2chr2_-_178129294-0.629.9e-02Click!


Activity profile for motif NFE2L2.p2.

activity profile for motif NFE2L2.p2


Sorted Z-values histogram for motif NFE2L2.p2

Sorted Z-values for motif NFE2L2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_56075329 1.634 NM_152637
METTL7B
methyltransferase like 7B
chr12_+_56075418 1.555 METTL7B
methyltransferase like 7B
chr5_-_75919051 0.665 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr1_+_223889253 0.657 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr16_+_53133063 0.628 CHD9
chromodomain helicase DNA binding protein 9
chr17_-_48264039 0.609 COL1A1
collagen, type I, alpha 1
chr1_-_162838550 0.601 NM_178550
C1orf110
chromosome 1 open reading frame 110
chr7_+_93551015 0.539 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chrX_+_9431314 0.534 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr22_-_44708730 0.515 NM_001099294
KIAA1644
KIAA1644
chr17_-_76921453 0.508 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr2_+_33359607 0.502 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr20_+_34742656 0.468 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr7_+_23286277 0.465 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr7_+_23286384 0.440 GPNMB
glycoprotein (transmembrane) nmb
chr22_+_22735202 0.437


chrX_+_30671602 0.420 GK
glycerol kinase
chr8_+_120428551 0.402 NM_002514
NOV
nephroblastoma overexpressed gene
chr17_-_76921205 0.382 TIMP2
TIMP metallopeptidase inhibitor 2
chrX_+_149531439 0.375 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr4_-_39033981 0.369 NM_024943
TMEM156
transmembrane protein 156
chr3_+_141043054 0.350 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr7_+_23286386 0.347 GPNMB
glycoprotein (transmembrane) nmb
chr1_-_84464728 0.346 NM_024686
TTLL7
tubulin tyrosine ligase-like family, member 7
chr19_+_36359346 0.344 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr12_-_56101465 0.339 ITGA7
integrin, alpha 7
chr1_+_159141376 0.337 NM_021189
NM_001127173
CADM3

cell adhesion molecule 3

chr4_+_123747939 0.333 FGF2
fibroblast growth factor 2 (basic)
chr11_-_102826433 0.323 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr7_+_23286390 0.323 GPNMB
glycoprotein (transmembrane) nmb
chr5_-_95158465 0.319 NM_001118890
NM_001243658
NM_001243659
NM_002064
GLRX



glutaredoxin (thioltransferase)



chr4_+_123747815 0.318 NM_002006
FGF2
fibroblast growth factor 2 (basic)
chr16_+_55512801 0.317 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr12_-_56101667 0.310 NM_001144996
NM_002206
ITGA7

integrin, alpha 7

chr19_-_51587466 0.303 NM_022046
KLK14
kallikrein-related peptidase 14
chr5_-_149535420 0.299 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr1_-_109969058 0.299 NM_001199772
NM_002790
NM_001199773
NM_001199774
PSMA5



proteasome (prosome, macropain) subunit, alpha type, 5



chr14_-_21572374 0.294


chr16_+_30076993 0.289 NM_001243177
NM_184041
ALDOA

aldolase A, fructose-bisphosphate

chr6_-_24877453 0.287 NM_015864
FAM65B
family with sequence similarity 65, member B
chr9_-_130341265 0.287 NM_001035534
FAM129B
family with sequence similarity 129, member B
chr2_-_224467049 0.282 SCG2
secretogranin II
chr17_-_28618836 0.277 BLMH
bleomycin hydrolase
chr2_-_224467095 0.273 SCG2
secretogranin II
chr11_-_67141647 0.271 NM_001166212
CLCF1
cardiotrophin-like cytokine factor 1
chr7_+_116312412 0.271 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr5_-_95158365 0.271 GLRX
glutaredoxin (thioltransferase)
chr9_-_95186559 0.270 NM_005014
OMD
osteomodulin
chr11_-_6341708 0.266 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr16_+_30077120 0.266 ALDOA
aldolase A, fructose-bisphosphate
chr16_+_30077146 0.261 ALDOA
aldolase A, fructose-bisphosphate
chr3_+_48507209 0.253 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr5_-_149535309 0.251 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr8_-_26724748 0.251 ADRA1A
adrenergic, alpha-1A-, receptor
chr16_+_30996462 0.251 NM_001142777
NM_001142778
NM_025193
HSD3B7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr5_+_179247911 0.250 SQSTM1
sequestosome 1
chr5_+_179247903 0.249 SQSTM1
sequestosome 1
chr5_+_159436155 0.249 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr14_-_106714594 0.247


chr4_+_15004297 0.247 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
CPEB2





cytoplasmic polyadenylation element binding protein 2





chr19_-_49222956 0.245 NM_001130915
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr16_+_27438578 0.244 NM_021798
IL21R
interleukin 21 receptor
chr15_-_40630272 0.243 C15orf52
chromosome 15 open reading frame 52
chr17_+_14204326 0.238 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr8_-_82395401 0.237 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr5_+_159436143 0.236 TTC1
tetratricopeptide repeat domain 1
chr17_-_33390676 0.233 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr2_-_224467142 0.232 NM_003469
SCG2
secretogranin II
chr16_+_83986826 0.225 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr3_-_186262114 0.225 NM_017541
CRYGS
crystallin, gamma S
chr3_+_148447966 0.220 NM_032049
AGTR1
angiotensin II receptor, type 1
chr3_+_69915374 0.217 NM_198177
MITF
microphthalmia-associated transcription factor
chr10_+_95848811 0.213 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr3_+_48507621 0.212 TREX1
three prime repair exonuclease 1
chr6_-_35696359 0.212 NM_001145775
FKBP5
FK506 binding protein 5
chr6_+_34206567 0.212 NM_145905
HMGA1
high mobility group AT-hook 1
chr7_+_94023872 0.210 NM_000089
COL1A2
collagen, type I, alpha 2
chr5_+_176875325 0.210 NM_001174102
PRR7
proline rich 7 (synaptic)
chr7_-_93519990 0.208 NM_006528
TFPI2
tissue factor pathway inhibitor 2
chr20_-_42839295 0.208 C20orf111
chromosome 20 open reading frame 111
chr5_-_172756505 0.208 NM_003714
STC2
stanniocalcin 2
chrX_+_153770458 0.207 NM_001099856
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chrX_-_19688991 0.206 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr4_+_87968191 0.204 AFF1
AF4/FMR2 family, member 1
chr19_-_46285746 0.202 DMPK
dystrophia myotonica-protein kinase
chr16_-_27899477 0.201 NM_144675
GSG1L
GSG1-like
chr4_-_80329354 0.201 NM_033214
GK2
glycerol kinase 2
chr12_+_78225068 0.200 NM_014903
NAV3
neuron navigator 3
chr9_-_86322593 0.198 UBQLN1
ubiquilin 1
chr17_+_80193649 0.197 NM_001206952
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr2_+_69201704 0.195 NM_019617
GKN1
gastrokine 1
chr10_-_71892514 0.193 AIFM2
apoptosis-inducing factor, mitochondrion-associated, 2
chr3_-_53916199 0.193 NM_022899
ACTR8
ARP8 actin-related protein 8 homolog (yeast)
chr12_-_102591547 0.193 NM_002674
PMCH
pro-melanin-concentrating hormone
chr22_+_22712091 0.192 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr5_+_145583112 0.192 RBM27
RNA binding motif protein 27
chr17_+_30677187 0.189 ZNF207
zinc finger protein 207
chr6_+_160542862 0.188 NM_003057
NM_153187
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr1_+_114493766 0.186 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr6_+_56819706 0.184 NM_152731
BEND6
BEN domain containing 6
chr3_+_11178778 0.183 NM_001098213
HRH1
histamine receptor H1
chr17_-_28619183 0.183 NM_000386
BLMH
bleomycin hydrolase
chrX_-_106960268 0.182 NM_004089
TSC22D3
TSC22 domain family, member 3
chrX_+_133371076 0.182 NM_001101357
CCDC160
coiled-coil domain containing 160
chr19_+_12863406 0.181 NM_017682
BEST2
bestrophin 2
chr18_+_31319154 0.180 ASXL3
additional sex combs like 3 (Drosophila)
chr1_+_27719151 0.179 NM_005281
GPR3
G protein-coupled receptor 3
chr8_-_145025043 0.179 NM_201380
PLEC
plectin
chr20_-_42839423 0.178 NM_016470
C20orf111
chromosome 20 open reading frame 111
chr22_+_22786283 0.176


chr18_+_158480 0.175 NM_001037334
NM_005151
USP14

ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)

chr5_-_137911039 0.174 HSPA9
heat shock 70kDa protein 9 (mortalin)
chr16_+_31366468 0.173 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr6_+_56819923 0.173 BEND6
BEN domain containing 6
chr17_+_47074749 0.173 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr5_+_179247841 0.173 NM_003900
SQSTM1
sequestosome 1
chr10_-_21462987 0.173 NEBL
nebulette
chr3_+_184038050 0.170 NM_004953
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr8_+_22210311 0.170 PIWIL2
piwi-like 2 (Drosophila)
chr18_+_158586 0.169 USP14
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr1_-_115880851 0.167 NM_002506
NGF
nerve growth factor (beta polypeptide)
chr5_+_179125362 0.166 CANX
calnexin
chr7_+_129932973 0.165 NM_001163446
NM_016352
CPA4

carboxypeptidase A4

chr7_-_115670774 0.165 TFEC
transcription factor EC
chr14_+_103800678 0.164 EIF5
eukaryotic translation initiation factor 5
chr12_-_39299335 0.163 NM_153634
CPNE8
copine VIII
chr17_+_73598139 0.163 MYO15B
myosin XVB pseudogene
chr2_+_231921625 0.163 PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr12_+_7023490 0.163 NM_001975
ENO2
enolase 2 (gamma, neuronal)
chr5_-_137911005 0.162 HSPA9
heat shock 70kDa protein 9 (mortalin)
chr5_+_140613937 0.161 PCDHB18
protocadherin beta 18 pseudogene
chr7_+_1200097 0.161


chrX_-_65859107 0.161 NM_001199687
EDA2R
ectodysplasin A2 receptor
chr22_+_23154240 0.160


chr15_-_35087748 0.156 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr14_+_23352430 0.155 NM_173527
REM2
RAS (RAD and GEM)-like GTP binding 2
chr13_+_44453419 0.153 NM_001128303
LACC1
laccase (multicopper oxidoreductase) domain containing 1
chr4_-_83933961 0.152 NM_001115007
LIN54
lin-54 homolog (C. elegans)
chr6_-_31704272 0.150 CLIC1
chloride intracellular channel 1
chr6_-_31704281 0.149 CLIC1
chloride intracellular channel 1
chr2_+_133174146 0.149 NM_001508
GPR39
G protein-coupled receptor 39
chr11_-_47447779 0.148 PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr16_-_1429612 0.148 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr7_+_23286420 0.148 GPNMB
glycoprotein (transmembrane) nmb
chrX_-_53350521 0.146 NM_001111125
IQSEC2
IQ motif and Sec7 domain 2
chr6_-_31704304 0.145 CLIC1
chloride intracellular channel 1
chr6_-_31704287 0.144 CLIC1
chloride intracellular channel 1
chr19_-_7764283 0.143 NM_001207019
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr11_+_63448868 0.143 NM_006054
NM_201428
NM_201429
NM_201430
RTN3



reticulon 3



chr10_-_71892596 0.142 NM_001198696
NM_032797
AIFM2

apoptosis-inducing factor, mitochondrion-associated, 2

chr3_-_53916087 0.141 ACTR8
ARP8 actin-related protein 8 homolog (yeast)
chr7_+_94024201 0.140 COL1A2
collagen, type I, alpha 2
chr3_-_194090459 0.140 NM_001135057
NM_130830
LRRC15

leucine rich repeat containing 15

chr19_-_46285645 0.140 DMPK
dystrophia myotonica-protein kinase
chr11_+_20070609 0.139 NAV2
neuron navigator 2
chr6_-_31704318 0.139 NM_001288
CLIC1
chloride intracellular channel 1
chr20_-_633844 0.139 NM_080725
SRXN1
sulfiredoxin 1
chr7_+_22766765 0.136 NM_000600
IL6
interleukin 6 (interferon, beta 2)
chr9_+_139921915 0.135 NM_207511
C9orf139
chromosome 9 open reading frame 139
chr8_-_42623928 0.135 NM_001199279
NM_004198
CHRNA6

cholinergic receptor, nicotinic, alpha 6

chr17_-_39623476 0.135 NM_002278
KRT32
keratin 32
chr1_-_114302093 0.135 PHTF1
putative homeodomain transcription factor 1
chr22_-_40859423 0.134 MKL1
megakaryoblastic leukemia (translocation) 1
chr1_-_225616556 0.132 NM_194442
LBR
lamin B receptor
chr2_+_113763448 0.132 NM_014440
IL36A
interleukin 36, alpha
chr11_-_47447457 0.132 PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr16_+_89988416 0.131 NM_001197181
TUBB3
tubulin, beta 3 class III
chr11_-_47447915 0.130 NM_002804
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr3_-_150920946 0.128 NM_013308
GPR171
G protein-coupled receptor 171
chr2_-_111334677 0.127 NM_005054
RGPD5
RANBP2-like and GRIP domain containing 5
chr16_+_31366529 0.127 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr3_+_183894736 0.124 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr4_+_154178525 0.123 TRIM2
tripartite motif containing 2
chr2_-_214016332 0.122 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr12_-_48119224 0.122 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr7_+_150434679 0.121 GIMAP5
GTPase, IMAP family member 5
chr6_+_74405856 0.119 CD109
CD109 molecule
chrX_+_12993224 0.119 NM_021109
TMSB4X
thymosin beta 4, X-linked
chr3_+_184038445 0.118 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr12_+_50794591 0.118 NM_001170803
NM_001170804
NM_001170808
NM_052879
NM_199188
NM_199190
LARP4





La ribonucleoprotein domain family, member 4





chr7_+_143058794 0.118 ZYX
zyxin
chr17_+_79650961 0.116 NM_004712
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr19_-_6670598 0.116 NM_003807
NM_172014
TNFSF14

tumor necrosis factor (ligand) superfamily, member 14

chr11_+_57228126 0.115 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr10_-_31288420 0.115 NM_001143769
ZNF438
zinc finger protein 438
chr20_+_24929862 0.115 NM_003650
CST7
cystatin F (leukocystatin)
chr3_-_172428773 0.114 NM_001146276
NM_001146277
NM_001146278
NM_020792
NCEH1



neutral cholesterol ester hydrolase 1



chr17_+_80317122 0.114 NM_207459
TEX19
testis expressed 19
chr1_+_154377847 0.114 IL6R
interleukin 6 receptor
chr20_+_2796947 0.113 NM_001167670
TMEM239
transmembrane protein 239
chr6_-_31704093 0.113 CLIC1
chloride intracellular channel 1
chr17_+_79651072 0.111 HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr3_-_178977678 0.111 NM_171829
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr2_+_110551965 0.110 NM_005054
RGPD5
RANBP2-like and GRIP domain containing 5
chr3_+_49027281 0.110 NM_177938
NM_177939
P4HTM

prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

chr19_+_1248548 0.110 NM_177401
MIDN
midnolin
chr11_+_35684342 0.110 NM_017583
TRIM44
tripartite motif containing 44
chr1_+_22351984 0.109 LINC00339
long intergenic non-protein coding RNA 339
chr2_+_109335906 0.109 NM_006267
RANBP2
RAN binding protein 2
chr9_-_140082983 0.108 ANAPC2
anaphase promoting complex subunit 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
5.46 2.19e-06 GO:0051351 positive regulation of ligase activity
5.89 4.71e-06 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
1.93 5.09e-06 GO:0050790 regulation of catalytic activity
6.67 6.40e-06 GO:0006521 regulation of cellular amino acid metabolic process
5.44 6.43e-06 GO:0051443 positive regulation of ubiquitin-protein ligase activity
6.18 6.52e-06 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
6.18 6.52e-06 GO:0072395 signal transduction involved in cell cycle checkpoint
6.18 6.52e-06 GO:0072401 signal transduction involved in DNA integrity checkpoint
6.18 6.52e-06 GO:0072404 signal transduction involved in G1/S transition checkpoint
6.18 6.52e-06 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
6.18 6.52e-06 GO:0072422 signal transduction involved in DNA damage checkpoint
6.18 6.52e-06 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
6.18 6.52e-06 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
5.64 9.63e-06 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.89 1.39e-05 GO:0071158 positive regulation of cell cycle arrest
4.76 2.47e-05 GO:0051340 regulation of ligase activity
5.63 2.85e-05 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
4.45 3.54e-05 GO:0000077 DNA damage checkpoint
5.20 3.59e-05 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.13 4.41e-05 GO:0031575 mitotic cell cycle G1/S transition checkpoint
5.13 4.41e-05 GO:0071779 G1/S transition checkpoint
5.38 5.58e-05 GO:0051352 negative regulation of ligase activity
5.38 5.58e-05 GO:0051444 negative regulation of ubiquitin-protein ligase activity
5.01 6.60e-05 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
4.71 7.11e-05 GO:0051438 regulation of ubiquitin-protein ligase activity
4.88 9.73e-05 GO:2000045 regulation of G1/S transition of mitotic cell cycle
5.52 1.06e-04 GO:0033238 regulation of cellular amine metabolic process
4.17 1.09e-04 GO:0031570 DNA integrity checkpoint
4.26 1.62e-04 GO:0090068 positive regulation of cell cycle process
4.66 2.04e-04 GO:0030330 DNA damage response, signal transduction by p53 class mediator
2.01 2.21e-04 GO:0044093 positive regulation of molecular function
4.14 2.59e-04 GO:0031398 positive regulation of protein ubiquitination
2.08 3.51e-04 GO:0043085 positive regulation of catalytic activity
1.71 3.54e-04 GO:0065009 regulation of molecular function
1.81 8.65e-04 GO:0051246 regulation of protein metabolic process
2.64 1.19e-03 GO:0031401 positive regulation of protein modification process
3.93 1.27e-03 GO:0000084 S phase of mitotic cell cycle
4.33 1.36e-03 GO:0031397 negative regulation of protein ubiquitination
1.82 1.42e-03 GO:0032268 regulation of cellular protein metabolic process
4.53 1.66e-03 GO:0000216 M/G1 transition of mitotic cell cycle
3.86 1.69e-03 GO:0051320 S phase
2.39 2.59e-03 GO:0032270 positive regulation of cellular protein metabolic process
3.34 4.34e-03 GO:0031396 regulation of protein ubiquitination
3.74 5.16e-03 GO:0042770 signal transduction in response to DNA damage
1.87 6.03e-03 GO:0006508 proteolysis
2.28 7.66e-03 GO:0051247 positive regulation of protein metabolic process
1.87 8.65e-03 GO:0031399 regulation of protein modification process
3.42 9.94e-03 GO:0007093 mitotic cell cycle checkpoint
2.05 1.41e-02 GO:0019725 cellular homeostasis
1.89 1.64e-02 GO:0006915 apoptosis
3.06 1.71e-02 GO:0010498 proteasomal protein catabolic process
3.06 1.71e-02 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.86 2.51e-02 GO:0012501 programmed cell death
1.77 2.86e-02 GO:0008219 cell death
1.19 2.99e-02 GO:0050789 regulation of biological process
1.76 3.33e-02 GO:0016265 death
1.34 3.49e-02 GO:0007165 signal transduction
1.18 3.61e-02 GO:0065007 biological regulation
3.05 4.96e-02 GO:0000082 G1/S transition of mitotic cell cycle

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
6.73 2.15e-08 GO:0000502 proteasome complex
1.70 1.22e-03 GO:0000267 cell fraction
1.73 1.04e-02 GO:0005626 insoluble fraction
1.69 2.90e-02 GO:0005624 membrane fraction
2.37 3.65e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
5.89 2.11e-03 GO:0003823 antigen binding
4.62 2.09e-02 GO:0005097 Rab GTPase activator activity