Motif ID: NFKB1_REL_RELA.p2

Z-value: 2.471


Transcription factors associated with NFKB1_REL_RELA.p2:

Gene SymbolEntrez IDGene Name
NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
REL 5966 v-rel reticuloendotheliosis viral oncogene homolog (avian)
RELA 5970 v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFKB1chr4_+_1034227300.944.3e-04Click!
RELchr2_+_611087750.811.6e-02Click!
RELAchr11_-_65430214-0.373.6e-01Click!


Activity profile for motif NFKB1_REL_RELA.p2.

activity profile for motif NFKB1_REL_RELA.p2


Sorted Z-values histogram for motif NFKB1_REL_RELA.p2

Sorted Z-values for motif NFKB1_REL_RELA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFKB1_REL_RELA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_51522953 4.434 NM_145888
KLK10
kallikrein-related peptidase 10
chr1_-_209825797 3.342 NM_000228
LAMB3
laminin, beta 3
chr1_-_209824641 3.189 NM_001017402
LAMB3
laminin, beta 3
chr12_-_58160823 2.887 NM_000785
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr1_+_46640748 2.871 NM_005727
TSPAN1
tetraspanin 1
chr6_+_30850693 2.788 DDR1
discoidin domain receptor tyrosine kinase 1
chr6_-_136847743 2.708 NM_001198614
NM_001198618
NM_001198619
MAP7


microtubule-associated protein 7


chr11_+_18287807 2.696 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr7_+_69064316 2.582 AUTS2
autism susceptibility candidate 2
chr20_+_43803539 2.511 NM_002638
PI3
peptidase inhibitor 3, skin-derived
chr6_-_136847078 2.508 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr19_-_4338750 2.460 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr1_-_209979388 2.430 NM_001206696
NM_006147
IRF6

interferon regulatory factor 6

chr6_-_136847609 2.392 MAP7
microtubule-associated protein 7
chr5_+_31639424 2.316 PDZD2
PDZ domain containing 2
chr2_-_74669005 2.296 RTKN
rhotekin
chr7_+_18548899 2.287 NM_001204147
NM_001204148
HDAC9

histone deacetylase 9

chr13_-_20806533 2.250 NM_001110219
NM_001110220
NM_001110221
GJB6


gap junction protein, beta 6, 30kDa


chr19_-_51456159 2.206 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr2_-_70781146 2.122 NM_001099691
NM_003236
TGFA

transforming growth factor, alpha

chr2_-_74669026 2.063 RTKN
rhotekin
chr19_-_51523272 2.026 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr2_-_70780621 2.015 TGFA
transforming growth factor, alpha
chr1_+_234040547 1.987 NM_173508
SLC35F3
solute carrier family 35, member F3
chr11_-_18270167 1.957 NM_001199744
NM_001127380
NM_030754
SAA2-SAA4
SAA2

SAA2-SAA4 readthrough
serum amyloid A2

chr2_+_68961912 1.927 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr8_-_139926235 1.873 NM_152888
COL22A1
collagen, type XXII, alpha 1
chr6_+_80340971 1.870 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr17_-_7197866 1.816 NM_015982
YBX2
Y box binding protein 2
chr20_+_44637539 1.793 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr18_+_33877630 1.792 NM_025135
FHOD3
formin homology 2 domain containing 3
chr1_-_159915382 1.766 NM_001135050
NM_020789
IGSF9

immunoglobulin superfamily, member 9

chr18_-_28681429 1.759 DSC2
desmocollin 2
chr6_+_125475334 1.722 NM_001003395
TPD52L1
tumor protein D52-like 1
chr1_+_200863948 1.718 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr12_-_28124915 1.671 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr15_+_41136178 1.645 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr9_-_124990706 1.643 NM_001242333
LHX6
LIM homeobox 6
chr2_-_235405692 1.624 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr3_+_113666544 1.618 NM_173570
ZDHHC23
zinc finger, DHHC-type containing 23
chr2_-_74669055 1.595 NM_001015055
RTKN
rhotekin
chr9_-_124990949 1.532 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr19_+_17905907 1.524 NM_014256
B3GNT3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
chr4_+_103422730 1.514 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr19_+_54371170 1.511 MYADM
myeloid-associated differentiation marker
chr9_+_115913266 1.506 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr16_+_67465019 1.497 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr1_-_161008710 1.457 TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr2_+_69001932 1.455 NM_001166276
NM_014882
ARHGAP25

Rho GTPase activating protein 25

chr15_-_75017710 1.446 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr1_-_24513737 1.416 NM_170743
NM_173064
NM_173065
IL28RA


interleukin 28 receptor, alpha (interferon, lambda receptor)


chr12_-_106532447 1.413 NUAK1
NUAK family, SNF1-like kinase, 1
chr14_-_22005035 1.402 NM_005407
SALL2
sal-like 2 (Drosophila)
chr1_+_3388170 1.369 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr11_+_66824308 1.366 RHOD
ras homolog gene family, member D
chr19_+_17905935 1.361 B3GNT3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
chr18_-_28742744 1.356 NM_004948
NM_024421
DSC1

desmocollin 1

chr17_+_54671059 1.347 NM_005450
NOG
noggin
chr12_-_8815266 1.324 MFAP5
microfibrillar associated protein 5
chr12_-_8815370 1.322 NM_003480
MFAP5
microfibrillar associated protein 5
chr8_-_95274540 1.311 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr4_+_103422822 1.310 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr19_+_45504686 1.301 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr19_-_11688441 1.277 ACP5
acid phosphatase 5, tartrate resistant
chr11_-_115088628 1.276 CADM1
cell adhesion molecule 1
chr1_-_209825673 1.273 NM_001127641
LAMB3
laminin, beta 3
chr4_-_120549115 1.262 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr16_+_3115611 1.256 NM_001012635
IL32
interleukin 32
chr7_+_86273219 1.253 NM_000840
GRM3
glutamate receptor, metabotropic 3
chr4_+_103422479 1.246 NM_001165412
NM_003998
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr10_-_135090325 1.221 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr11_-_118016134 1.217 NM_001142349
SCN4B
sodium channel, voltage-gated, type IV, beta
chr8_+_21912327 1.209 NM_001114136
NM_001114139
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr1_-_183560010 1.209 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr9_+_38392696 1.202 ALDH1B1
aldehyde dehydrogenase 1 family, member B1
chr2_-_31361591 1.200 NM_001253826
NM_024572
GALNT14

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)

chr16_+_3115312 1.196 NM_001012631
NM_001012633
NM_001012718
NM_004221
IL32



interleukin 32



chr1_+_26872342 1.194 NM_001006665
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_-_7197896 1.183 YBX2
Y box binding protein 2
chr2_-_163174816 1.182 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr9_-_117568292 1.181 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr16_-_57318574 1.169 NM_015993
PLLP
plasmolipin
chr16_+_3115638 1.157 NM_001012634
IL32
interleukin 32
chr6_+_53659788 1.156 LRRC1
leucine rich repeat containing 1
chr1_+_26856252 1.153 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr14_+_65171243 1.149 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr4_+_103422553 1.148 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr17_-_4642638 1.143 CXCL16
chemokine (C-X-C motif) ligand 16
chr1_+_26872306 1.136 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_-_24469571 1.135 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr19_-_38747171 1.135 NM_001243947
NM_033256
PPP1R14A

protein phosphatase 1, regulatory (inhibitor) subunit 14A

chr10_+_104154228 1.135 NM_001077493
NM_001077494
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr2_+_113993082 1.131 LOC654433
uncharacterized LOC654433
chr17_+_8924822 1.127 NM_004822
NTN1
netrin 1
chr18_+_23806385 1.122 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr16_+_3115639 1.117 IL32
interleukin 32
chr4_+_106816627 1.114 NPNT
nephronectin
chr5_+_167718485 1.113 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr2_-_31361284 1.111 GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr8_-_66754276 1.110 PDE7A
phosphodiesterase 7A
chr8_+_101170510 1.104 NM_003114
SPAG1
sperm associated antigen 1
chr1_-_21059132 1.104 NM_001103160
NM_001103161
SH2D5

SH2 domain containing 5

chr19_-_38746978 1.094 PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr6_+_106534188 1.089 NM_001198
PRDM1
PR domain containing 1, with ZNF domain
chr8_-_95274520 1.085 GEM
GTP binding protein overexpressed in skeletal muscle
chr11_-_119234628 1.060 USP2
ubiquitin specific peptidase 2
chr6_+_14117486 1.051 NM_001251901
CD83
CD83 molecule
chr7_-_102920665 1.042 DPY19L2P2
dpy-19-like 2 pseudogene 2 (C. elegans)
chr5_+_36606667 1.041 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_-_8815479 1.040 MFAP5
microfibrillar associated protein 5
chr16_-_57318452 1.036 PLLP
plasmolipin
chr6_+_53659738 1.018 NM_018214
LRRC1
leucine rich repeat containing 1
chr11_+_102188180 1.011 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr19_+_1067536 1.009 HMHA1
histocompatibility (minor) HA-1
chr1_-_183559669 0.998 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr20_-_46415277 0.998 NM_001161841
NM_198596
SULF2

sulfatase 2

chr17_+_9548853 0.992 NM_153210
USP43
ubiquitin specific peptidase 43
chr9_+_38392700 0.990 ALDH1B1
aldehyde dehydrogenase 1 family, member B1
chr14_+_65171149 0.977 NM_015549
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr17_-_4643162 0.974 NM_001100812
NM_022059
CXCL16

chemokine (C-X-C motif) ligand 16

chr10_-_73533196 0.969 NM_022153
C10orf54
chromosome 10 open reading frame 54
chr9_+_38392658 0.950 NM_000692
ALDH1B1
aldehyde dehydrogenase 1 family, member B1
chr6_+_116692098 0.948 NM_013352
DSE
dermatan sulfate epimerase
chr12_-_85306539 0.948 SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr12_+_7055736 0.943 NM_080548
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr14_+_103243813 0.924 NM_001199427
NM_003300
NM_145725
NM_145726
TRAF3



TNF receptor-associated factor 3



chr9_+_130911731 0.917 NM_005564
LCN2
lipocalin 2
chr8_+_104831415 0.911 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr19_+_3136026 0.910 NM_002068
GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr4_-_22517339 0.906 NM_145290
GPR125
G protein-coupled receptor 125
chr10_+_104155431 0.899 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr1_+_183155393 0.885 LAMC2
laminin, gamma 2
chr6_+_109762204 0.883 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr3_-_52090090 0.881 NM_001947
DUSP7
dual specificity phosphatase 7
chr2_+_64681610 0.875 LGALSL
lectin, galactoside-binding-like
chr17_+_35294771 0.874 NM_005568
LHX1
LIM homeobox 1
chr11_+_66824285 0.869 NM_014578
RHOD
ras homolog gene family, member D
chr17_-_39675078 0.867 NM_002275
KRT15
keratin 15
chr8_-_144810691 0.866 FAM83H
family with sequence similarity 83, member H
chr1_-_186649421 0.863 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr12_-_85306579 0.850 NM_001146335
NM_018057
NM_182767
SLC6A15


solute carrier family 6 (neutral amino acid transporter), member 15


chr19_+_54371125 0.848 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr18_+_61420276 0.843 NM_001040147
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_-_161008733 0.837 NM_001113205
NM_001113206
NM_001113207
TSTD1


F11R
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1


F11 receptor
chr6_+_14118002 0.825 CD83
CD83 molecule
chr6_+_7541837 0.822 DSP
desmoplakin
chr4_-_76944585 0.815 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chrX_+_17653412 0.813 NM_001136024
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr4_-_103422436 0.813


chr16_-_2059759 0.798 NM_178167
ZNF598
zinc finger protein 598
chr1_+_26856259 0.796 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr3_+_111718006 0.794 NM_001008273
TAGLN3
transgelin 3
chr19_+_38755422 0.792 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr10_-_116286661 0.783 NM_006720
ABLIM1
actin binding LIM protein 1
chr19_+_14142611 0.782 IL27RA
interleukin 27 receptor, alpha
chr4_+_74735107 0.778 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr20_+_3024267 0.777 NM_001501
NM_178331
NM_178332
GNRH2


gonadotropin-releasing hormone 2


chr2_+_27665232 0.770 NM_001168364
NM_173853
KRTCAP3

keratinocyte associated protein 3

chr18_+_55711890 0.767 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr15_+_89182038 0.767 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr14_-_35873823 0.763 NM_020529
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr2_+_233925104 0.762 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr11_+_59522801 0.761 STX3
syntaxin 3
chr14_+_103243832 0.758 TRAF3
TNF receptor-associated factor 3
chr17_+_7461591 0.754 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr1_-_85462622 0.754 NM_153259
MCOLN2
mucolipin 2
chr12_-_6740814 0.750 NM_001142961
LPAR5
lysophosphatidic acid receptor 5
chr19_+_14142459 0.748 IL27RA
interleukin 27 receptor, alpha
chr1_+_40420837 0.746 MFSD2A
major facilitator superfamily domain containing 2A
chr8_-_145641828 0.746 NM_017767
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr19_+_41222915 0.742 NM_025194
ITPKC
inositol-trisphosphate 3-kinase C
chr12_+_7055753 0.740 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr6_+_130339715 0.738 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr3_+_10857867 0.736 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr16_+_3096681 0.735 NM_022468
MMP25
matrix metallopeptidase 25
chr2_+_233925035 0.732 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr17_-_34122547 0.731 NM_001032278
NM_024302
MMP28

matrix metallopeptidase 28

chr1_-_93426998 0.727 NM_001006605
NM_001252269
NM_001252270
NM_001252273
FAM69A



family with sequence similarity 69, member A



chr8_-_15095791 0.723 NM_139167
SGCZ
sarcoglycan, zeta
chr3_+_36421944 0.721 NM_003149
STAC
SH3 and cysteine rich domain
chr1_+_203274646 0.719 NM_006763
BTG2
BTG family, member 2
chr11_-_118134986 0.718 MPZL2
myelin protein zero-like 2
chr11_+_69924407 0.715 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr6_-_155777036 0.709 NM_015718
NOX3
NADPH oxidase 3
chr2_+_26568900 0.708 NM_033505
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr17_+_78075299 0.702 NM_000152
NM_001079803
NM_001079804
GAA


glucosidase, alpha; acid


chr6_+_37137882 0.702 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr20_-_4795768 0.696 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr1_+_26856240 0.693 NM_002953
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr3_+_132757216 0.687 TMEM108
transmembrane protein 108
chr1_+_167599329 0.686 NM_052862
RCSD1
RCSD domain containing 1
chr11_+_121322848 0.685 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr19_+_41223282 0.685 ITPKC
inositol-trisphosphate 3-kinase C
chr1_+_183155361 0.684 LAMC2
laminin, gamma 2
chr17_+_65373574 0.684 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr15_+_59730272 0.681 NM_152450
FAM81A
family with sequence similarity 81, member A
chr2_+_61108724 0.680 NM_002908
REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr6_-_136871542 0.677 MAP7
microtubule-associated protein 7
chr2_+_61108775 0.675 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr8_-_66753968 0.671 NM_001242318
PDE7A
phosphodiesterase 7A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.13 5.23e-09 GO:0009987 cellular process
1.42 5.71e-09 GO:0048518 positive regulation of biological process
1.44 1.10e-08 GO:0048522 positive regulation of cellular process
1.17 6.92e-07 GO:0065007 biological regulation
1.19 2.18e-06 GO:0050794 regulation of cellular process
1.28 1.05e-05 GO:0023052 signaling
1.17 1.33e-05 GO:0050789 regulation of biological process
1.31 1.26e-04 GO:0048731 system development
1.29 1.71e-04 GO:0048856 anatomical structure development
1.27 2.25e-04 GO:0007275 multicellular organismal development
1.51 2.38e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.64 3.15e-04 GO:0006955 immune response
1.53 3.59e-04 GO:0010941 regulation of cell death
1.53 3.92e-04 GO:0043067 regulation of programmed cell death
1.54 3.97e-04 GO:0042981 regulation of apoptosis
1.48 4.37e-04 GO:0009893 positive regulation of metabolic process
1.26 6.48e-04 GO:0007165 signal transduction
1.24 1.18e-03 GO:0032502 developmental process
1.32 1.19e-03 GO:0048519 negative regulation of biological process
1.64 1.78e-03 GO:0010628 positive regulation of gene expression
1.22 2.45e-03 GO:0051716 cellular response to stimulus
1.45 2.63e-03 GO:0002376 immune system process
1.58 5.50e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.44 6.04e-03 GO:0031325 positive regulation of cellular metabolic process
1.31 1.13e-02 GO:0048523 negative regulation of cellular process
1.33 1.30e-02 GO:0048513 organ development
2.23 2.06e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
2.63 2.43e-02 GO:0051222 positive regulation of protein transport
2.27 2.44e-02 GO:0034762 regulation of transmembrane transport
2.83 2.71e-02 GO:0002699 positive regulation of immune effector process
7.06 2.78e-02 GO:0002828 regulation of type 2 immune response
1.22 3.20e-02 GO:0060255 regulation of macromolecule metabolic process
1.17 3.39e-02 GO:0043170 macromolecule metabolic process
1.31 3.69e-02 GO:0048583 regulation of response to stimulus
1.80 4.09e-02 GO:0045597 positive regulation of cell differentiation
1.50 4.56e-02 GO:0048584 positive regulation of response to stimulus
1.54 4.69e-02 GO:0002682 regulation of immune system process
1.68 4.98e-02 GO:0051094 positive regulation of developmental process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.32 2.68e-04 GO:0044459 plasma membrane part
10.09 4.19e-03 GO:0033256 I-kappaB/NF-kappaB complex
1.12 4.73e-03 GO:0016020 membrane
1.18 1.33e-02 GO:0005886 plasma membrane
1.18 1.66e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 4.11e-07 GO:0005515 protein binding
1.08 4.97e-04 GO:0005488 binding