Motif ID: NR1H4.p2

Z-value: 1.012


Transcription factors associated with NR1H4.p2:

Gene SymbolEntrez IDGene Name
NR1H4 9971 nuclear receptor subfamily 1, group H, member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR1H4chr12_+_1008675500.492.2e-01Click!


Activity profile for motif NR1H4.p2.

activity profile for motif NR1H4.p2


Sorted Z-values histogram for motif NR1H4.p2

Sorted Z-values for motif NR1H4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1H4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_103031797 0.765 PLP1
proteolipid protein 1
chr1_+_45274153 0.704 NM_001136537
BTBD19
BTB (POZ) domain containing 19
chrX_+_103031433 0.686 NM_001128834
PLP1
proteolipid protein 1
chrX_+_103031753 0.651 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr7_+_100199881 0.645 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr6_+_31623668 0.572 NM_019101
APOM
apolipoprotein M
chr17_-_53809444 0.568 NM_001099640
TMEM100
transmembrane protein 100
chr17_+_1665306 0.566 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr6_+_31623688 0.565 APOM
apolipoprotein M
chr5_+_149569810 0.553 SLC6A7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr5_+_32710742 0.552 NM_001204376
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr17_+_1665233 0.544 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_1665281 0.516 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr5_+_149569519 0.510 NM_014228
SLC6A7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr17_+_1665342 0.505 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chrX_-_154250769 0.468 NM_000132
F8
coagulation factor VIII, procoagulant component
chr11_+_63304272 0.404 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr12_+_53442732 0.398 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr19_-_42894419 0.384 NM_032488
CNFN
cornifelin
chr3_-_187452669 0.370 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr11_+_10879763 0.368 LOC729013
uncharacterized LOC729013
chr19_+_35629727 0.359 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr19_-_58864820 0.355 NM_130786
A1BG
alpha-1-B glycoprotein
chr9_-_96215873 0.347 NM_198841
FAM120AOS
family with sequence similarity 120A opposite strand
chr2_-_85637486 0.346 NM_001747
CAPG
capping protein (actin filament), gelsolin-like
chr1_+_156024516 0.344 NM_001145264
NM_014017
LAMTOR2

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

chr16_-_2336874 0.340


chr6_-_31698033 0.333 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chrX_-_118827322 0.333 NM_015129
NM_145799
NM_145800
NM_145802
SEPT6



septin 6



chr4_-_186697065 0.321 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr4_+_62362838 0.320 NM_015236
LPHN3
latrophilin 3
chr2_-_91847961 0.319


chr20_+_36531498 0.312 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chr19_+_10197023 0.312 C19orf66
chromosome 19 open reading frame 66
chr11_+_62380212 0.309 NM_000327
ROM1
retinal outer segment membrane protein 1
chr19_+_10196972 0.301 C19orf66
chromosome 19 open reading frame 66
chr4_-_100242487 0.297 NM_000668
ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr8_-_12973752 0.294 NM_001164271
DLC1
deleted in liver cancer 1
chr17_-_19651586 0.291 NM_000691
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr6_-_109415514 0.288 NM_014454
SESN1
sestrin 1
chr8_+_110346549 0.284 NM_001193557
NM_020189
ENY2

enhancer of yellow 2 homolog (Drosophila)

chr5_-_139944045 0.282 NM_006051
NM_133172
NM_133173
NM_133174
APBB3



amyloid beta (A4) precursor protein-binding, family B, member 3



chr3_+_45067750 0.282 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr2_+_210288668 0.274 NM_001039538
MAP2
microtubule-associated protein 2
chr7_-_92777657 0.257 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr5_-_139943829 0.257 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr1_-_150849043 0.252 ARNT
aryl hydrocarbon receptor nuclear translocator
chr18_+_66465316 0.238 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr3_-_112359277 0.236 CCDC80
coiled-coil domain containing 80
chr2_-_190044330 0.231 NM_000393
COL5A2
collagen, type V, alpha 2
chr1_-_150849211 0.229 NM_001197325
NM_001668
NM_178427
ARNT


aryl hydrocarbon receptor nuclear translocator


chr11_+_67250504 0.229 NM_003977
AIP
aryl hydrocarbon receptor interacting protein
chr2_-_85637473 0.229 CAPG
capping protein (actin filament), gelsolin-like
chr3_-_112358510 0.227 CCDC80
coiled-coil domain containing 80
chr14_-_75078669 0.226 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr11_+_114167197 0.225 NNMT
nicotinamide N-methyltransferase
chr19_-_44860798 0.223 NM_001083335
NM_013380
ZFP112

zinc finger protein 112 homolog (mouse)

chr1_-_144997110 0.219 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr16_+_67700704 0.217 NM_001012984
C16orf86
chromosome 16 open reading frame 86
chr9_+_74526527 0.217 C9orf85
chromosome 9 open reading frame 85
chr6_-_85472312 0.216 TBX18
T-box 18
chr15_-_83474805 0.215 NM_001007122
FSD2
fibronectin type III and SPRY domain containing 2
chr9_-_139890984 0.213 NM_004669
CLIC3
chloride intracellular channel 3
chr1_-_151804225 0.213 NM_005060
RORC
RAR-related orphan receptor C
chr11_+_114167168 0.213 NNMT
nicotinamide N-methyltransferase
chr1_-_149908098 0.213 NM_181873
MTMR11
myotubularin related protein 11
chr3_-_49851217 0.210 UBA7
ubiquitin-like modifier activating enzyme 7
chr22_+_30792929 0.210 NM_001204204
NM_012429
NM_033382
SEC14L2


SEC14-like 2 (S. cerevisiae)


chr3_+_184055275 0.209 NM_144635
FAM131A
family with sequence similarity 131, member A
chr5_+_178450775 0.206 NM_001136116
ZNF879
zinc finger protein 879
chr8_+_70405080 0.204 SULF1
sulfatase 1
chr16_-_4562979 0.204 C16orf5
chromosome 16 open reading frame 5
chr3_-_112359251 0.203 CCDC80
coiled-coil domain containing 80
chr1_+_154300275 0.201 NM_020452
ATP8B2
ATPase, class I, type 8B, member 2
chr17_+_41177247 0.200 NM_005440
RND2
Rho family GTPase 2
chr3_+_190105660 0.199 NM_006580
CLDN16
claudin 16
chr14_+_100531745 0.198 NM_016337
EVL
Enah/Vasp-like
chrX_+_149613719 0.198 NM_001177466
NM_005491
MAMLD1

mastermind-like domain containing 1

chr10_-_21814610 0.195 NM_207371
C10orf140
chromosome 10 open reading frame 140
chr3_-_112358758 0.194 CCDC80
coiled-coil domain containing 80
chr9_+_131191206 0.191 CERCAM
cerebral endothelial cell adhesion molecule
chr1_-_36789754 0.191 NM_018166
FAM176B
family with sequence similarity 176, member B
chr1_-_150849062 0.191 ARNT
aryl hydrocarbon receptor nuclear translocator
chr1_-_16939687 0.191 NM_017940
NBPF1
neuroblastoma breakpoint family, member 1
chrX_-_118827060 0.190 SEPT6
septin 6
chr12_-_57914287 0.186 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr6_+_127587984 0.185 RNF146
ring finger protein 146
chr20_-_44455932 0.184 NM_003279
TNNC2
troponin C type 2 (fast)
chr6_+_127587826 0.183 NM_001242851
NM_001242844
NM_001242849
NM_001242852
NM_001242845
NM_001242846
NM_001242850
NM_030963
RNF146







ring finger protein 146







chr22_+_32149936 0.182 NM_001242897
DEPDC5
DEP domain containing 5
chr8_-_57359148 0.182 NM_001135690
PENK
proenkephalin
chr19_-_50143350 0.182 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr21_+_46707949 0.181 LOC642852
uncharacterized LOC642852
chr19_+_51226593 0.181 NM_002975
CLEC11A
C-type lectin domain family 11, member A
chr10_+_69869249 0.180 NM_032578
MYPN
myopalladin
chr22_+_30163351 0.179 NM_001003684
NM_013387
UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chrX_+_7137471 0.179 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chrX_-_118827116 0.178 SEPT6
septin 6
chr20_-_3149070 0.177 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr1_-_150849147 0.176 ARNT
aryl hydrocarbon receptor nuclear translocator
chr6_+_132891460 0.175 NM_175067
TAAR6
trace amine associated receptor 6
chr4_+_41992547 0.174 SLC30A9
solute carrier family 30 (zinc transporter), member 9
chr5_+_139944411 0.174 NM_080670
SLC35A4
solute carrier family 35, member A4
chr22_+_32150002 0.173 NM_001007188
NM_001242896
NM_014662
DEPDC5


DEP domain containing 5


chr14_-_25103365 0.172 NM_004131
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr8_+_72756335 0.171


chr8_+_70405027 0.170 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr17_-_33390676 0.169 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr3_-_160117314 0.169 NM_001190241
NM_020800
IFT80

intraflagellar transport 80 homolog (Chlamydomonas)

chr19_-_51875790 0.168 NM_005601
NKG7
natural killer cell group 7 sequence
chr11_+_45868956 0.167 NM_021117
CRY2
cryptochrome 2 (photolyase-like)
chr13_+_31506809 0.166 NM_152325
C13orf26
chromosome 13 open reading frame 26
chr19_+_51226638 0.166 CLEC11A
C-type lectin domain family 11, member A
chr3_-_195306274 0.166 APOD
apolipoprotein D
chr4_-_69817478 0.165 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr1_+_110230417 0.165 NM_000561
NM_146421
GSTM1

glutathione S-transferase mu 1

chr20_-_5295014 0.165 NM_144773
PROKR2
prokineticin receptor 2
chr6_-_31697568 0.163 DDAH2
dimethylarginine dimethylaminohydrolase 2
chrX_-_153640358 0.162 NM_001009932
NM_001009933
NM_001009934
DNASE1L1


deoxyribonuclease I-like 1


chr19_-_3062191 0.162 NM_001130
NM_198970
AES

amino-terminal enhancer of split

chr3_-_28390506 0.161 NM_001134432
NM_001134433
NM_022461
AZI2


5-azacytidine induced 2


chr16_+_28875181 0.161 NM_001145812
NM_015503
SH2B1

SH2B adaptor protein 1

chr19_+_54606141 0.160 NM_004542
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr1_+_46769336 0.160 NM_006004
UQCRH
ubiquinol-cytochrome c reductase hinge protein
chr19_+_10563581 0.158 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chr11_+_67777788 0.158 NM_000694
NM_001030010
ALDH3B1

aldehyde dehydrogenase 3 family, member B1

chr7_+_44078677 0.158 FLJ35390
uncharacterized LOC255031
chr11_-_63993562 0.158 NM_001033678
NM_001160389
NM_001160390
NM_001160392
NM_031472
TRPT1




tRNA phosphotransferase 1




chr1_+_171283372 0.158 NM_002022
FMO4
flavin containing monooxygenase 4
chr3_-_49726081 0.157 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr1_+_90024271 0.157 NM_015350
LRRC8B
leucine rich repeat containing 8 family, member B
chr16_+_67207755 0.157 NM_003946
NM_001185057
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr17_+_73975297 0.156 NM_001113324
TEN1
TEN1-CDK3
TEN1 telomerase capping complex subunit homolog (S. cerevisiae)
TEN1-CDK3 readthrough
chr13_+_32605436 0.156 NM_023037
FRY
furry homolog (Drosophila)
chr19_-_17516383 0.154 NM_004335
BST2
bone marrow stromal cell antigen 2
chr4_+_77870864 0.153 NM_018243
SEPT11
septin 11
chr19_+_54415990 0.152 NM_031896
CACNG7
calcium channel, voltage-dependent, gamma subunit 7
chr14_+_24025188 0.152 NM_001126339
NM_024328
THTPA

thiamine triphosphatase

chr1_+_59775749 0.152 NM_001244714
FGGY
FGGY carbohydrate kinase domain containing
chr5_-_150537335 0.151 NM_001155
ANXA6
annexin A6
chr11_+_67777795 0.150 ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr11_-_63381940 0.150 NM_001128203
PLA2G16
phospholipase A2, group XVI
chr4_+_41992492 0.149 NM_006345
SLC30A9
solute carrier family 30 (zinc transporter), member 9
chr3_-_28390280 0.148 AZI2
5-azacytidine induced 2
chr11_+_67250595 0.148 AIP
aryl hydrocarbon receptor interacting protein
chr16_+_2039945 0.148 NM_004209
SYNGR3
synaptogyrin 3
chr12_+_56511969 0.148 NM_032786
ZC3H10
zinc finger CCCH-type containing 10
chr9_-_16727887 0.147 BNC2
basonuclin 2
chr15_-_100273620 0.147 NM_152449
LYSMD4
LysM, putative peptidoglycan-binding, domain containing 4
chrX_-_118827155 0.146 SEPT6
septin 6
chr5_+_79330990 0.146 NM_003248
THBS4
thrombospondin 4
chr17_-_9939873 0.145 GAS7
growth arrest-specific 7
chr22_+_32149962 0.144 DEPDC5
DEP domain containing 5
chr3_-_50383009 0.144 NM_015896
ZMYND10
zinc finger, MYND-type containing 10
chr5_+_137419580 0.144 NM_058244
WNT8A
wingless-type MMTV integration site family, member 8A
chr11_-_63381907 0.143 NM_007069
PLA2G16
phospholipase A2, group XVI
chr11_-_65640199 0.143 NM_016938
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr10_-_90750955 0.143 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr11_-_6341708 0.142 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr14_-_21945031 0.142 NM_032846
RAB2B
RAB2B, member RAS oncogene family
chr3_-_105421044 0.140 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr1_+_145727712 0.138 PDZK1
PDZ domain containing 1
chr11_+_27015833 0.138 FIBIN
fin bud initiation factor homolog (zebrafish)
chr1_-_167905078 0.137 BRP44
brain protein 44
chr4_+_25915805 0.136 NM_001145432
C4orf52
chromosome 4 open reading frame 52
chr4_+_77870944 0.135 SEPT11
septin 11
chr16_+_53133063 0.135 CHD9
chromodomain helicase DNA binding protein 9
chrX_-_65835845 0.134 NM_001242310
EDA2R
ectodysplasin A2 receptor
chr10_-_121302149 0.134 NM_001005339
RGS10
regulator of G-protein signaling 10
chr19_-_3062911 0.134 NM_198969
AES
amino-terminal enhancer of split
chr6_+_2245965 0.133


chr22_+_19705990 0.133 SEPT5-GP1BB
SEPT5-GP1BB readthrough
chr19_+_1026608 0.133 CNN2
calponin 2
chr1_-_167905214 0.132 BRP44
brain protein 44
chr14_-_106111114 0.132 IGHG2
immunoglobulin heavy constant gamma 2 (G2m marker)
chr1_+_210502639 0.132 NM_001170580
HHAT
hedgehog acyltransferase
chr11_-_46717657 0.131 ARHGAP1
Rho GTPase activating protein 1
chr21_-_28339405 0.130 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr12_+_100661158 0.128 SCYL2
SCY1-like 2 (S. cerevisiae)
chr19_+_44037287 0.127 NM_174945
ZNF575
zinc finger protein 575
chr3_-_49851356 0.124 NM_003335
UBA7
ubiquitin-like modifier activating enzyme 7
chr3_-_187454247 0.124 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr11_+_63273555 0.124 LGALS12
lectin, galactoside-binding, soluble, 12
chr3_+_52489646 0.124 NISCH
nischarin
chr15_+_40698000 0.124 IVD
isovaleryl-CoA dehydrogenase
chr9_+_116343169 0.124 RGS3
regulator of G-protein signaling 3
chr11_-_63381840 0.124 PLA2G16
phospholipase A2, group XVI
chr19_+_6372805 0.123 ALKBH7
alkB, alkylation repair homolog 7 (E. coli)
chr19_+_18496966 0.121 NM_004864
GDF15
growth differentiation factor 15
chr4_+_41614725 0.120 LIMCH1
LIM and calponin homology domains 1
chr6_+_107349327 0.120 NM_001142468
NM_001142470
NM_016487
C6orf203


chromosome 6 open reading frame 203


chr1_+_171217632 0.119 NM_002021
FMO1
flavin containing monooxygenase 1
chr20_-_34287043 0.118 NM_001198989
NM_021100
NFS1

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)

chr17_+_18647325 0.118 NM_031456
FBXW10
F-box and WD repeat domain containing 10
chr19_+_36239445 0.118 LIN37
lin-37 homolog (C. elegans)
chr1_+_44457231 0.117 NM_152499
CCDC24
coiled-coil domain containing 24
chr17_-_3704437 0.117 ITGAE
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
chr16_+_23652686 0.116 NM_001199011
NM_001199743
NM_032486
DCTN5


dynactin 5 (p25)


chr17_+_78161598 0.116 NM_052819
CARD14
caspase recruitment domain family, member 14
chr18_+_47340328 0.116



Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.42 6.12e-03 GO:0005739 mitochondrion
2.49 1.57e-02 GO:0044455 mitochondrial membrane part

Nothing significant found in function category.