Motif ID: NR3C1.p2

Z-value: 0.684


Transcription factors associated with NR3C1.p2:

Gene SymbolEntrez IDGene Name
NR3C1 2908 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR3C1chr5_-_142783200-0.245.7e-01Click!


Activity profile for motif NR3C1.p2.

activity profile for motif NR3C1.p2


Sorted Z-values histogram for motif NR3C1.p2

Sorted Z-values for motif NR3C1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR3C1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_139163222 0.325 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr11_+_111126706 0.272 NM_198498
C11orf53
chromosome 11 open reading frame 53
chr3_-_111314181 0.213 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr10_+_695887 0.205 C10orf108
chromosome 10 open reading frame 108
chr1_-_186417855 0.199 NM_022576
PDC
phosducin
chr11_-_58343308 0.194 NM_004811
LPXN
leupaxin
chr4_+_36285643 0.190 NM_001170700
DTHD1
death domain containing 1
chr2_-_237172987 0.186 NM_212556
ASB18
ankyrin repeat and SOCS box containing 18
chr1_+_173793817 0.160 DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr8_+_32504250 0.154 NM_013959
NRG1
neuregulin 1
chr7_-_122339186 0.137 NM_139175
RNF133
ring finger protein 133
chr19_-_5790913 0.133 DUS3L
dihydrouridine synthase 3-like (S. cerevisiae)
chr10_+_114043413 0.130 NM_058222
TECTB
tectorin beta
chr7_-_97501680 0.130 ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr7_+_23286386 0.127 GPNMB
glycoprotein (transmembrane) nmb
chr19_+_15783827 0.126 NM_023944
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chr22_+_45704821 0.124 NM_001104595
FAM118A
family with sequence similarity 118, member A
chr8_-_110655418 0.118 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr1_-_183622447 0.115 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr3_-_121264780 0.112 NM_199420
POLQ
polymerase (DNA directed), theta
chr11_-_59633942 0.112 NM_001062
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr2_-_233877920 0.108 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr21_-_46340821 0.106 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_-_102826433 0.106 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr10_+_70847817 0.105 NM_002727
SRGN
serglycin
chr5_-_16738346 0.101 MYO10
myosin X
chr1_+_32645322 0.100 NM_175852
TXLNA
taxilin alpha
chr17_-_39306053 0.096 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr1_+_210001363 0.096 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr1_+_210001351 0.094 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr2_-_45795104 0.093 SRBD1
S1 RNA binding domain 1
chr1_-_160492982 0.091 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr1_+_158223926 0.090 NM_001763
CD1A
CD1a molecule
chr21_-_46340776 0.090 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_-_31648140 0.090 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr6_-_132967141 0.088 NM_138327
TAAR1
trace amine associated receptor 1
chr1_+_84874033 0.088 NM_058248
DNASE2B
deoxyribonuclease II beta
chr15_-_74501309 0.088 NM_001142617
NM_001142619
NM_001142620
STRA6


stimulated by retinoic acid gene 6 homolog (mouse)


chr1_+_210001267 0.087 NM_014388
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr2_-_202563353 0.087 NM_033066
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr4_+_113970784 0.087 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr7_-_96654128 0.085 NM_005221
DLX5
distal-less homeobox 5
chr6_-_32191779 0.083 NM_004557
NOTCH4
notch 4
chr9_+_125281418 0.083 NM_001004452
OR1J4
olfactory receptor, family 1, subfamily J, member 4
chr11_-_121986800 0.080 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr19_-_36643770 0.077 NM_001864
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr13_-_47470967 0.076 NM_000621
NM_001165947
HTR2A

5-hydroxytryptamine (serotonin) receptor 2A

chr1_-_94586678 0.076 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr8_+_26150731 0.076 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr14_-_92333856 0.075 NM_001128596
TC2N
tandem C2 domains, nuclear
chr10_+_5488521 0.074 NM_005863
NET1
neuroepithelial cell transforming 1
chr3_+_148583042 0.074 NM_001870
CPA3
carboxypeptidase A3 (mast cell)
chr11_-_47510518 0.074 NM_001025596
NM_001172640
CELF1

CUGBP, Elav-like family member 1

chr2_+_108602978 0.074 NM_021815
SLC5A7
solute carrier family 5 (choline transporter), member 7
chr10_-_90611675 0.071 NM_144590
ANKRD22
ankyrin repeat domain 22
chr14_-_45722604 0.071 NM_018353
MIS18BP1
MIS18 binding protein 1
chr1_+_162602308 0.071 DDR2
discoidin domain receptor tyrosine kinase 2
chr17_-_8055684 0.070 NM_002616
PER1
period homolog 1 (Drosophila)
chr5_-_172755418 0.070 STC2
stanniocalcin 2
chr10_+_13203547 0.070 NM_018518
NM_182751
MCM10

minichromosome maintenance complex component 10

chr3_-_149375584 0.068 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chrX_-_70326637 0.068 NM_001025265
CXorf65
chromosome X open reading frame 65
chr3_+_46448678 0.066 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr14_+_74083547 0.066 NM_001037162
ACOT6
acyl-CoA thioesterase 6
chr12_+_50869531 0.065 LARP4
La ribonucleoprotein domain family, member 4
chr4_+_37962055 0.062 NM_006607
PTTG2
pituitary tumor-transforming 2
chr22_-_17073440 0.062 NM_014406
CCT8L2
chaperonin containing TCP1, subunit 8 (theta)-like 2
chr22_+_37678565 0.061 CYTH4
cytohesin 4
chr11_-_57195052 0.060 NM_017611
SLC43A3
solute carrier family 43, member 3
chr1_-_10856704 0.058 NM_001079843
NM_017766
CASZ1

castor zinc finger 1

chr19_-_2038937 0.058 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr6_+_64231626 0.058 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr12_+_5153084 0.058 NM_002234
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr20_+_56136136 0.057 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr20_+_51801821 0.057 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr17_-_70588942 0.057 LOC100499467
uncharacterized LOC100499467
chr1_+_210001399 0.056 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr11_+_111895537 0.056 NM_001931
DLAT
dihydrolipoamide S-acetyltransferase
chr11_-_115088628 0.055 CADM1
cell adhesion molecule 1
chr6_+_26156558 0.054 NM_005321
HIST1H1E
histone cluster 1, H1e
chr7_+_23286390 0.053 GPNMB
glycoprotein (transmembrane) nmb
chr22_-_42336222 0.053 NM_001110215
CENPM
centromere protein M
chr14_-_106714594 0.053


chr8_-_110346272 0.053 NM_032869
NUDCD1
NudC domain containing 1
chr22_+_41074994 0.053 NM_005297
MCHR1
melanin-concentrating hormone receptor 1
chr7_+_117864711 0.053 NM_019644
ANKRD7
ankyrin repeat domain 7
chrX_+_30671602 0.052 GK
glycerol kinase
chr15_+_59908908 0.052 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr8_+_103563847 0.051 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr17_+_45286427 0.051 NM_001002841
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr6_+_26156552 0.049 HIST1H1E
histone cluster 1, H1e
chr2_-_238499317 0.049 RAB17
RAB17, member RAS oncogene family
chr7_-_104909442 0.049 NM_182691
SRPK2
SRSF protein kinase 2
chr17_-_35656691 0.049 NM_198837
NM_198838
ACACA

acetyl-CoA carboxylase alpha

chr1_+_165797060 0.048 UCK2
uridine-cytidine kinase 2
chr14_-_106774311 0.046 IGHA1
immunoglobulin heavy constant alpha 1
chr8_+_54793516 0.046 RGS20
regulator of G-protein signaling 20
chr1_+_43766565 0.046 NM_001253357
NM_005424
TIE1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

chr3_-_52090090 0.046 NM_001947
DUSP7
dual specificity phosphatase 7
chr17_+_21308447 0.045 NM_001194958
KCNJ18
potassium inwardly-rectifying channel, subfamily J, member 18
chr22_+_44395090 0.045 NM_001003828
PARVB
parvin, beta
chr19_-_3500937 0.045 NM_001145165
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr19_+_7702010 0.044 STXBP2
syntaxin binding protein 2
chr8_-_62602285 0.044 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr6_-_29323971 0.044 NM_030876
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr7_+_127233688 0.044 NM_020369
FSCN3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr6_-_53409897 0.043 NM_001197115
NM_001498
GCLC

glutamate-cysteine ligase, catalytic subunit

chrX_-_151877669 0.043 NM_001129826
NM_001129828
NM_001080848
NM_004909
CSAG3

CSAG2

CSAG family, member 3

CSAG family, member 2

chr2_+_159651828 0.043 NM_001017920
DAPL1
death associated protein-like 1
chr11_+_44785975 0.043 NM_130783
TSPAN18
tetraspanin 18
chr3_-_123339423 0.042 NM_053031
NM_053032
MYLK

myosin light chain kinase

chrX_+_123234462 0.042 STAG2
stromal antigen 2
chrX_+_151927733 0.042 NM_001129828
NM_001129826
NM_001080848
NM_004909
CSAG3

CSAG2

CSAG family, member 3

CSAG family, member 2

chr17_+_34171647 0.042 TAF15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr16_-_31228394 0.042 NM_152901
PYDC1
PYD (pyrin domain) containing 1
chr6_-_75970566 0.041 TMEM30A
transmembrane protein 30A
chr5_-_156772672 0.041 NM_001001343
FNDC9
fibronectin type III domain containing 9
chr11_-_47545539 0.041 NM_001172639
CELF1
CUGBP, Elav-like family member 1
chr1_-_170038055 0.041 NM_001204517
KIFAP3
kinesin-associated protein 3
chrX_+_128913897 0.041 SASH3
SAM and SH3 domain containing 3
chr2_+_182321618 0.041 NM_000885
ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr9_+_43684800 0.041 NM_001201380
CNTNAP3B
contactin associated protein-like 3B
chr4_+_72204769 0.041 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr6_+_33359312 0.040 NM_002263
KIFC1
kinesin family member C1
chr16_+_31366468 0.040 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr2_-_158300517 0.040 NM_004288
CYTIP
cytohesin 1 interacting protein
chr4_-_155511838 0.040 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr8_-_110657745 0.040 NM_001099751
NM_001099752
SYBU

syntabulin (syntaxin-interacting)

chr10_-_123353330 0.039 NM_001144913
NM_001144914
FGFR2

fibroblast growth factor receptor 2

chr19_-_2456954 0.039 NM_032737
LMNB2
lamin B2
chrX_+_128913881 0.039 NM_018990
SASH3
SAM and SH3 domain containing 3
chr19_+_7701976 0.039 NM_001127396
NM_006949
STXBP2

syntaxin binding protein 2

chr7_-_97501737 0.038 NM_001178075
NM_001178076
NM_001673
NM_183356
ASNS



asparagine synthetase (glutamine-hydrolyzing)



chrY_-_20935503 0.038 NM_001001877
NM_153716
NM_152584
NM_033108
HSFY2

HSFY1

heat shock transcription factor, Y linked 2

heat shock transcription factor, Y-linked 1

chr19_-_9609243 0.037 NM_152476
ZNF560
zinc finger protein 560
chr16_-_21222867 0.037 NM_003460
ZP2
zona pellucida glycoprotein 2 (sperm receptor)
chr5_+_35856990 0.037 NM_002185
IL7R
interleukin 7 receptor
chr10_-_32345293 0.037 KIF5B
kinesin family member 5B
chr22_+_35462125 0.036 NM_001008494
ISX
intestine-specific homeobox
chr12_-_91452130 0.036 NM_007035
KERA
keratocan
chr21_+_41239346 0.036 NM_006198
PCP4
Purkinje cell protein 4
chrY_+_20708556 0.036 NM_153716
NM_001001877
NM_033108
NM_152584
HSFY2

HSFY1

heat shock transcription factor, Y linked 2

heat shock transcription factor, Y-linked 1

chr1_-_151798552 0.035 NM_001001523
RORC
RAR-related orphan receptor C
chr2_-_75796847 0.034 NM_032181
FAM176A
family with sequence similarity 176, member A
chr1_+_107682628 0.034 NM_001113226
NM_001113228
NM_014917
NTNG1


netrin G1


chr11_-_36619776 0.034 NM_000536
NM_001243785
NM_001243786
RAG2


recombination activating gene 2


chr6_+_31638727 0.034 NM_021221
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chrX_+_30671456 0.033 NM_000167
NM_001128127
NM_001205019
NM_203391
GK



glycerol kinase



chr20_+_43835637 0.033 NM_003007
SEMG1
semenogelin I
chr11_-_57194512 0.032 NM_014096
SLC43A3
solute carrier family 43, member 3
chr21_+_30400229 0.032 USP16
ubiquitin specific peptidase 16
chr20_+_9198036 0.032 NM_182797
PLCB4
phospholipase C, beta 4
chr14_+_24616707 0.032 RNF31
ring finger protein 31
chr8_+_62200524 0.032 NM_173519
CLVS1
clavesin 1
chr12_-_56679729 0.032 CS
citrate synthase
chr12_-_117742856 0.031 NM_001204213
NOS1
nitric oxide synthase 1 (neuronal)
chr6_-_132022540 0.031 NM_030908
OR2A4
olfactory receptor, family 2, subfamily A, member 4
chr18_+_32398225 0.031 NM_001198942
NM_001198944
NM_032980
NM_032981
DTNA



dystrobrevin, alpha



chr12_-_57443858 0.031 NM_005379
MYO1A
myosin IA
chr18_-_24442534 0.031 NM_004028
AQP4
aquaporin 4
chr14_+_65877309 0.031 NM_004480
NM_178155
NM_178156
FUT8


fucosyltransferase 8 (alpha (1,6) fucosyltransferase)


chr11_+_45825873 0.030 SLC35C1
solute carrier family 35, member C1
chr15_-_50647275 0.030 GABPB1
GA binding protein transcription factor, beta subunit 1
chr19_+_15121538 0.030 NM_173482
CCDC105
coiled-coil domain containing 105
chr5_+_180467224 0.030 NM_152547
BTNL9
butyrophilin-like 9
chr16_-_20702577 0.030 NM_052956
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr16_+_4545858 0.030 NM_001127205
HMOX2
heme oxygenase (decycling) 2
chr1_+_41157241 0.030 NM_001142587
NM_001142588
NM_001142589
NM_014223
NFYC



nuclear transcription factor Y, gamma



chr4_+_71494460 0.030 NM_031889
ENAM
enamelin
chr16_-_24968856 0.029 ARHGAP17
Rho GTPase activating protein 17
chr1_-_59147727 0.029


chr1_+_192127591 0.029 NM_130782
RGS18
regulator of G-protein signaling 18
chr12_-_120687956 0.029 NM_025157
PXN
paxillin
chr12_+_52347163 0.029 NM_020327
ACVR1B
activin A receptor, type IB
chr11_+_18287807 0.029 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chrX_+_46940235 0.028 RGN
regucalcin (senescence marker protein-30)
chr14_-_88793250 0.028 NM_021161
KCNK10
potassium channel, subfamily K, member 10
chr6_-_136788012 0.028 NM_001198615
MAP7
microtubule-associated protein 7
chr1_-_153085963 0.028 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr1_-_152386727 0.028 NM_016190
CRNN
cornulin
chr1_-_182922504 0.028 NM_030933
SHCBP1L
SHC SH2-domain binding protein 1-like
chr10_-_123353771 0.028 NM_001144916
FGFR2
fibroblast growth factor receptor 2
chr6_+_158733691 0.028 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr10_-_32345337 0.028 NM_004521
KIF5B
kinesin family member 5B
chr12_-_123706393 0.028 NM_022782
MPHOSPH9
M-phase phosphoprotein 9
chr20_+_43850009 0.028 NM_003008
SEMG2
semenogelin II
chr15_+_40886217 0.028 CASC5
cancer susceptibility candidate 5
chr2_-_163008913 0.027 NM_002054
GCG
glucagon
chr11_-_102745666 0.027 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr1_+_162602198 0.027 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr8_+_54793409 0.027 NM_003702
RGS20
regulator of G-protein signaling 20
chr11_-_57194556 0.027 SLC43A3
solute carrier family 43, member 3
chr11_-_57194591 0.027 NM_199329
SLC43A3
solute carrier family 43, member 3
chr6_+_4890225 0.027 NM_001143971
CDYL
chromodomain protein, Y-like
chr13_-_60587298 0.027 NM_030932
DIAPH3
diaphanous homolog 3 (Drosophila)
chr6_+_41196061 0.027 NM_198153
TREML4
triggering receptor expressed on myeloid cells-like 4
chr3_+_151488214 0.026 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr8_-_66701175 0.026 NM_002603
PDE7A
phosphodiesterase 7A
chr2_-_43453724 0.026 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr12_+_3068442 0.026 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4



Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.31 1.42e-02 GO:0005886 plasma membrane
1.30 2.08e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
6.28 1.11e-02 GO:0003823 antigen binding