Motif ID: NRF1.p2

Z-value: 4.691


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NRF1chr7_+_1292699160.561.4e-01Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_49449638 5.049 NM_022171
TCTA
T-cell leukemia translocation altered gene
chr17_+_260092 4.922 NM_001013672
C17orf97
chromosome 17 open reading frame 97
chr3_+_49449753 4.599 TCTA
T-cell leukemia translocation altered gene
chr5_+_119800004 4.558 NM_016644
PRR16
proline rich 16
chr5_+_119799898 4.547 PRR16
proline rich 16
chr7_+_149571029 4.433 ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr22_+_24666749 3.141 NM_001145468
NM_015330
SPECC1L

sperm antigen with calponin homology and coiled-coil domains 1-like

chrX_+_51927918 3.030 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chrX_-_51812249 2.985 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chr12_-_54070108 2.513 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr13_-_44361032 2.452 NM_001242863
NM_017993
ENOX1

ecto-NOX disulfide-thiol exchanger 1

chr19_-_44124013 2.433 NM_182498
ZNF428
zinc finger protein 428
chr5_+_134181729 2.351 C5orf24
chromosome 5 open reading frame 24
chr19_-_44123732 2.255 ZNF428
zinc finger protein 428
chr13_-_49107250 2.208 NM_001268
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr12_-_124457099 2.169 NM_025140
CCDC92
coiled-coil domain containing 92
chr11_+_63706433 2.150 NM_024771
NAA40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr15_-_48937068 2.148 FBN1
fibrillin 1
chr13_-_49107185 2.135 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr9_+_134378335 2.132 POMT1
protein-O-mannosyltransferase 1
chrX_+_54835492 2.068 NM_201222
MAGED2
melanoma antigen family D, 2
chr9_+_134378353 2.020 POMT1
protein-O-mannosyltransferase 1
chr1_+_183605207 2.002 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr19_-_18391440 1.996


chr3_+_73045939 1.968 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr14_-_61115906 1.964 NM_005982
SIX1
SIX homeobox 1
chr3_+_73046081 1.959 NM_174907
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr11_+_113931228 1.953 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr21_+_45553546 1.903 C21orf33
chromosome 21 open reading frame 33
chr20_-_35580045 1.898 SAMHD1
SAM domain and HD domain 1
chr20_-_35580109 1.879 SAMHD1
SAM domain and HD domain 1
chr2_+_37311593 1.876 NM_174931
CCDC75
coiled-coil domain containing 75
chr19_+_56159400 1.860 CCDC106
coiled-coil domain containing 106
chr19_-_40023449 1.860 NM_152361
EID2B
EP300 interacting inhibitor of differentiation 2B
chr12_-_54069856 1.855 ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr4_-_7044664 1.855 NM_153376
CCDC96
coiled-coil domain containing 96
chr16_-_2390737 1.814 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr20_-_35580186 1.788 NM_015474
SAMHD1
SAM domain and HD domain 1
chr22_-_31741761 1.782 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr22_-_29075708 1.766 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr16_-_2390711 1.761 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr12_+_107349539 1.755 NM_152261
C12orf23
chromosome 12 open reading frame 23
chr6_-_33679435 1.739 C6orf125
chromosome 6 open reading frame 125
chr7_-_149570763 1.720 LOC401431
uncharacterized LOC401431
chr20_-_35580175 1.717 SAMHD1
SAM domain and HD domain 1
chr6_-_33679501 1.689 NM_032340
C6orf125
chromosome 6 open reading frame 125
chr12_-_54673901 1.674 NM_012117
CBX5
chromobox homolog 5
chr5_+_92920592 1.668 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr3_+_43732358 1.664 NM_016006
ABHD5
abhydrolase domain containing 5
chr3_-_49449400 1.661 RHOA
ras homolog gene family, member A
chr21_+_48055589 1.658 PRMT2
protein arginine methyltransferase 2
chr21_+_48055585 1.651 PRMT2
protein arginine methyltransferase 2
chr12_+_107349673 1.643 C12orf23
chromosome 12 open reading frame 23
chr5_+_134181545 1.620 NM_001135586
C5orf24
chromosome 5 open reading frame 24
chr12_-_54673879 1.612 CBX5
chromobox homolog 5
chr1_-_16939687 1.596 NM_017940
NBPF1
neuroblastoma breakpoint family, member 1
chr19_-_5622725 1.594 SAFB2
scaffold attachment factor B2
chr16_-_2390593 1.582 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr1_+_197871681 1.582 NM_001024594
C1orf53
chromosome 1 open reading frame 53
chr5_-_111093792 1.575 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr19_-_6199536 1.569


chr6_+_41040891 1.568 NFYA
nuclear transcription factor Y, alpha
chr2_-_19558371 1.536 NM_145260
OSR1
odd-skipped related 1 (Drosophila)
chr22_-_31742217 1.522 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr10_-_50747038 1.520 ERCC6
excision repair cross-complementing rodent repair deficiency, complementation group 6
chr10_-_127511832 1.516 NM_000375
UROS
uroporphyrinogen III synthase
chr7_+_158649200 1.502 NM_018051
WDR60
WD repeat domain 60
chr19_-_53662279 1.493 NM_001172674
NM_001172675
NM_032584
ZNF347


zinc finger protein 347


chr3_-_185826332 1.478 ETV5
ets variant 5
chr3_-_49449393 1.436 RHOA
ras homolog gene family, member A
chr19_-_46405854 1.429 NM_001012643
MYPOP
Myb-related transcription factor, partner of profilin
chr19_+_14544216 1.400 PKN1
protein kinase N1
chr10_-_124639077 1.380 NM_001204364
NM_152644
FAM24B-CUZD1
FAM24B

FAM24B-CUZD1 readthrough
family with sequence similarity 24, member B

chr19_+_4304590 1.368 NM_024333
FSD1
fibronectin type III and SPRY domain containing 1
chr9_-_74061819 1.350 TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr8_-_95907423 1.349 NM_057749
CCNE2
cyclin E2
chr22_-_20850075 1.337 NM_032775
KLHL22
kelch-like 22 (Drosophila)
chr13_+_21714684 1.337 SAP18
Sin3A-associated protein, 18kDa
chr19_-_50432731 1.337 NUP62
nucleoporin 62kDa
chr20_-_30539803 1.329 PDRG1
p53 and DNA-damage regulated 1
chr13_+_21714652 1.315 NM_005870
SAP18
Sin3A-associated protein, 18kDa
chr20_-_35402142 1.299 NM_001145316
NM_024918
NM_001145315
NM_001145317
NM_001145318
DSN1




DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)




chr3_-_49449423 1.290 RHOA
ras homolog gene family, member A
chr7_-_72971868 1.284 BCL7B
B-cell CLL/lymphoma 7B
chr7_+_142985462 1.277 CASP2
caspase 2, apoptosis-related cysteine peptidase
chr22_-_31742329 1.269 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr11_-_9286832 1.269 NM_001243254
NM_015213
DENND5A

DENN/MADD domain containing 5A

chr6_+_41040687 1.258 NM_002505
NM_021705
NFYA

nuclear transcription factor Y, alpha

chr20_-_30539725 1.253 PDRG1
p53 and DNA-damage regulated 1
chr2_+_71295407 1.251 NM_017567
NAGK
N-acetylglucosamine kinase
chr3_-_49449525 1.240 NM_001664
RHOA
ras homolog gene family, member A
chr2_+_28113598 1.239 BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr1_-_47133982 1.237 ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr9_+_91003238 1.231 NM_006717
SPIN1
spindlin 1
chr14_-_60097314 1.226 RTN1
reticulon 1
chr4_+_6675654 1.226 LOC93622
Morf4 family associated protein 1-like 1 pseudogene
chr7_-_72972021 1.223 NM_001197244
NM_001707
BCL7B

B-cell CLL/lymphoma 7B

chr4_-_39640461 1.221 NM_174921
C4orf34
chromosome 4 open reading frame 34
chr13_-_49107357 1.208 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr21_+_48055506 1.208 NM_001242864
NM_001242865
NM_001242866
NM_001535
NM_206962
PRMT2




protein arginine methyltransferase 2




chr1_-_110282908 1.203 GSTM3
glutathione S-transferase mu 3 (brain)
chr19_+_18794487 1.202 CRTC1
CREB regulated transcription coactivator 1
chrX_+_51636608 1.198 NM_001005333
NM_006986
MAGED1

melanoma antigen family D, 1

chr21_-_47648685 1.196 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr1_-_28969516 1.194 NM_001135218
NM_005644
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr16_+_89939992 1.192 NM_014972
TCF25
transcription factor 25 (basic helix-loop-helix)
chr3_-_49449357 1.189 RHOA
ras homolog gene family, member A
chr20_+_39657461 1.185 NM_003286
TOP1
topoisomerase (DNA) I
chr20_-_42839423 1.180 NM_016470
C20orf111
chromosome 20 open reading frame 111
chr17_-_76778306 1.178 NM_004762
NM_017456
CYTH1

cytohesin 1

chr20_+_39657612 1.178 TOP1
topoisomerase (DNA) I
chr9_-_115774471 1.176 NM_001101338
ZNF883
zinc finger protein 883
chr5_-_178054001 1.170 NM_020666
CLK4
CDC-like kinase 4
chr10_-_16859389 1.170 RSU1
Ras suppressor protein 1
chr3_-_49449409 1.166 RHOA
ras homolog gene family, member A
chr21_+_45553485 1.159 NM_004649
NM_198155
C21orf33

chromosome 21 open reading frame 33

chr15_+_42787850 1.153 SNAP23
synaptosomal-associated protein, 23kDa
chr1_-_47134039 1.152 NM_001042546
NM_022745
ATPAF1

ATP synthase mitochondrial F1 complex assembly factor 1

chr5_-_179050635 1.149 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr20_+_34042908 1.140 NM_007186
CEP250
centrosomal protein 250kDa
chr12_-_120554453 1.140 RAB35
RAB35, member RAS oncogene family
chr5_-_139682680 1.138 NM_002622
PFDN1
prefoldin subunit 1
chr19_-_36236291 1.137 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr6_+_43543877 1.133 NM_006502
POLH
polymerase (DNA directed), eta
chr10_-_127511795 1.130 UROS
uroporphyrinogen III synthase
chr5_-_90679115 1.127 NM_020801
ARRDC3
arrestin domain containing 3
chrX_-_153707595 1.121 NM_006014
LAGE3
L antigen family, member 3
chr9_+_134378324 1.115 POMT1
protein-O-mannosyltransferase 1
chr20_+_11871364 1.106 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr13_-_20357081 1.106 PSPC1
paraspeckle component 1
chr8_+_38854431 1.105 NM_003816
ADAM9
ADAM metallopeptidase domain 9
chr4_+_6675798 1.104 LOC93622
Morf4 family associated protein 1-like 1 pseudogene
chr19_+_14017038 1.104 CC2D1A
coiled-coil and C2 domain containing 1A
chr4_+_668312 1.103 MYL5
myosin, light chain 5, regulatory
chr1_+_151170978 1.103 NM_001135636
NM_001135637
NM_001135638
NM_003557
PIP5K1A



phosphatidylinositol-4-phosphate 5-kinase, type I, alpha



chr9_+_4985082 1.102 JAK2
Janus kinase 2
chr14_-_60097223 1.100 RTN1
reticulon 1
chr19_-_36909463 1.098 NM_133466
ZFP82
zinc finger protein 82 homolog (mouse)
chr16_+_15528324 1.096 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr6_-_88875766 1.094 NM_001160226
NM_001160258
NM_001160259
NM_016083
CNR1



cannabinoid receptor 1 (brain)



chr2_+_28113612 1.093 BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr13_+_114238978 1.091 TFDP1
transcription factor Dp-1
chr6_+_41040713 1.089 NFYA
nuclear transcription factor Y, alpha
chr19_+_18118921 1.086 NM_015683
ARRDC2
arrestin domain containing 2
chr9_+_134378271 1.081 NM_001077365
NM_001077366
NM_001136113
NM_001136114
NM_007171
POMT1




protein-O-mannosyltransferase 1




chr3_-_48885217 1.077 PRKAR2A
protein kinase, cAMP-dependent, regulatory, type II, alpha
chr20_-_30539853 1.070 NM_030815
PDRG1
p53 and DNA-damage regulated 1
chr5_-_178054072 1.068 CLK4
CDC-like kinase 4
chr1_-_202858225 1.066 NM_002871
RABIF
RAB interacting factor
chr4_+_668250 1.066 MYL5
myosin, light chain 5, regulatory
chr19_+_56915382 1.065 NM_001159860
ZNF583
zinc finger protein 583
chr9_+_134378334 1.057 POMT1
protein-O-mannosyltransferase 1
chr17_+_21279667 1.057 NM_021012
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr20_-_42839295 1.056 C20orf111
chromosome 20 open reading frame 111
chr10_-_50747080 1.055 NM_000124
ERCC6
PGBD3
excision repair cross-complementing rodent repair deficiency, complementation group 6
piggyBac transposable element derived 3
chr18_-_5296013 1.054 NM_001143823
NM_003409
ZFP161

zinc finger protein 161 homolog (mouse)

chr19_-_19144304 1.028 SUGP2
SURP and G patch domain containing 2
chr9_+_45441902 1.027 LOC100132167
uncharacterized LOC100132167
chr11_-_1330883 1.025 TOLLIP
toll interacting protein
chr22_-_31741565 1.024 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr3_-_185826748 1.022 NM_004454
ETV5
ets variant 5
chr9_+_115142395 1.021 HSDL2
hydroxysteroid dehydrogenase like 2
chr19_+_3762671 1.017 MRPL54
mitochondrial ribosomal protein L54
chr9_-_100459623 1.014 NM_000380
XPA
xeroderma pigmentosum, complementation group A
chr8_+_42249383 1.012 VDAC3
voltage-dependent anion channel 3
chr3_+_10157314 1.007 NM_018462
BRK1
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr6_+_43543921 1.006 POLH
polymerase (DNA directed), eta
chr19_-_50432678 1.005 NUP62
nucleoporin 62kDa
chr2_-_198175494 1.002 NM_001195144
NM_153697
ANKRD44

ankyrin repeat domain 44

chr13_-_21348081 1.002 N6AMT2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr1_+_246887591 1.000 SCCPDH
saccharopine dehydrogenase (putative)
chr17_-_16472463 0.997 NM_020653
ZNF287
zinc finger protein 287
chr19_+_56915693 0.996 NM_152478
NM_001159861
ZNF583

zinc finger protein 583

chr10_+_102820914 0.995 NM_030929
KAZALD1
Kazal-type serine peptidase inhibitor domain 1
chr22_+_32340592 0.987 YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr14_+_100438095 0.980 EVL
Enah/Vasp-like
chr19_+_3762650 0.975 NM_172251
MRPL54
mitochondrial ribosomal protein L54
chr3_-_178789535 0.971 ZMAT3
zinc finger, matrin-type 3
chr15_+_41952641 0.971 MGA
MAX gene associated
chr9_-_100459556 0.967 XPA
xeroderma pigmentosum, complementation group A
chr16_+_31191470 0.964 FUS
fused in sarcoma
chr3_-_122134881 0.963 NM_019069
WDR5B
WD repeat domain 5B
chr9_+_4985243 0.957 NM_004972
JAK2
Janus kinase 2
chr16_+_31191461 0.957 FUS
fused in sarcoma
chr9_+_115142188 0.954 NM_001195822
NM_032303
HSDL2

hydroxysteroid dehydrogenase like 2

chr11_-_1330891 0.954 NM_019009
TOLLIP
toll interacting protein
chr16_+_2802634 0.953 SRRM2
serine/arginine repetitive matrix 2
chr13_-_21348054 0.950 NM_174928
N6AMT2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr5_+_154238196 0.949 NM_004779
CNOT8
CCR4-NOT transcription complex, subunit 8
chr19_-_58609606 0.940 NM_001145543
NM_001145544
NM_023926
ZSCAN18


zinc finger and SCAN domain containing 18


chr19_-_5622794 0.940 NM_014649
SAFB2
scaffold attachment factor B2
chr19_+_5623119 0.938 SAFB
scaffold attachment factor B
chr10_-_127511693 0.931 UROS
uroporphyrinogen III synthase
chr5_+_178450775 0.925 NM_001136116
ZNF879
zinc finger protein 879
chr3_-_48885028 0.925 PRKAR2A
protein kinase, cAMP-dependent, regulatory, type II, alpha
chr3_-_50374749 0.924 RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr7_+_142985307 0.923 NM_032982
NM_032983
CASP2

caspase 2, apoptosis-related cysteine peptidase

chr21_+_38445562 0.922 NM_001001894
TTC3
tetratricopeptide repeat domain 3
chr6_+_31126340 0.919 TCF19
transcription factor 19
chr11_+_67250504 0.919 NM_003977
AIP
aryl hydrocarbon receptor interacting protein

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.41 8.84e-22 GO:0044260 cellular macromolecule metabolic process
1.31 5.48e-21 GO:0044237 cellular metabolic process
1.51 3.35e-18 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56 2.45e-16 GO:0090304 nucleic acid metabolic process
1.44 4.33e-16 GO:0034641 cellular nitrogen compound metabolic process
1.42 2.39e-15 GO:0006807 nitrogen compound metabolic process
1.32 2.51e-15 GO:0043170 macromolecule metabolic process
1.23 1.16e-13 GO:0008152 metabolic process
1.23 1.17e-11 GO:0044238 primary metabolic process
1.56 3.28e-11 GO:0006996 organelle organization
1.42 4.64e-11 GO:0071842 cellular component organization at cellular level
1.41 6.81e-11 GO:0071841 cellular component organization or biogenesis at cellular level
1.49 5.31e-10 GO:0010467 gene expression
1.50 1.99e-09 GO:0016070 RNA metabolic process
1.96 2.80e-09 GO:0016071 mRNA metabolic process
1.72 1.84e-08 GO:0033554 cellular response to stress
1.32 2.45e-08 GO:0016043 cellular component organization
1.31 2.48e-08 GO:0071840 cellular component organization or biogenesis
1.69 4.32e-08 GO:0045184 establishment of protein localization
1.61 4.69e-08 GO:0008104 protein localization
1.83 4.77e-08 GO:0051276 chromosome organization
2.17 2.18e-07 GO:0008380 RNA splicing
1.66 2.83e-07 GO:0015031 protein transport
1.87 4.45e-07 GO:0006974 response to DNA damage stimulus
1.69 4.80e-07 GO:0046907 intracellular transport
2.01 5.09e-07 GO:0006397 mRNA processing
1.80 6.51e-07 GO:0006259 DNA metabolic process
2.41 8.02e-07 GO:0000375 RNA splicing, via transesterification reactions
1.72 1.76e-06 GO:0022403 cell cycle phase
1.49 2.50e-06 GO:0033036 macromolecule localization
2.38 2.59e-06 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.38 2.59e-06 GO:0000398 nuclear mRNA splicing, via spliceosome
1.34 3.13e-06 GO:0044267 cellular protein metabolic process
1.85 5.23e-06 GO:0006325 chromatin organization
1.49 6.47e-06 GO:0051641 cellular localization
1.99 8.26e-06 GO:0006281 DNA repair
1.54 1.20e-05 GO:0007049 cell cycle
1.61 1.99e-05 GO:0022402 cell cycle process
1.40 2.20e-05 GO:0034645 cellular macromolecule biosynthetic process
1.25 2.56e-05 GO:0031323 regulation of cellular metabolic process
1.40 2.74e-05 GO:0009059 macromolecule biosynthetic process
1.26 2.86e-05 GO:0060255 regulation of macromolecule metabolic process
1.96 3.92e-05 GO:0070647 protein modification by small protein conjugation or removal
1.25 5.54e-05 GO:0080090 regulation of primary metabolic process
1.82 5.77e-05 GO:0000279 M phase
2.04 5.98e-05 GO:0032446 protein modification by small protein conjugation
1.52 7.86e-05 GO:0032774 RNA biosynthetic process
2.00 8.52e-05 GO:0006366 transcription from RNA polymerase II promoter
1.89 1.02e-04 GO:0016568 chromatin modification
2.05 1.34e-04 GO:0016567 protein ubiquitination
1.47 2.21e-04 GO:0051649 establishment of localization in cell
1.09 2.23e-04 GO:0009987 cellular process
1.67 2.28e-04 GO:0000278 mitotic cell cycle
1.63 3.19e-04 GO:0006396 RNA processing
2.24 3.69e-04 GO:0006913 nucleocytoplasmic transport
1.52 5.08e-04 GO:0006351 transcription, DNA-dependent
2.21 5.33e-04 GO:0051169 nuclear transport
1.44 5.71e-04 GO:0044248 cellular catabolic process
1.21 8.05e-04 GO:0019222 regulation of metabolic process
2.66 1.29e-03 GO:0022904 respiratory electron transport chain
1.26 1.54e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 2.52e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.66 3.34e-03 GO:0034621 cellular macromolecular complex subunit organization
2.01 3.43e-03 GO:0009203 ribonucleoside triphosphate catabolic process
2.01 3.43e-03 GO:0009207 purine ribonucleoside triphosphate catabolic process
1.27 3.92e-03 GO:0044249 cellular biosynthetic process
2.00 3.99e-03 GO:0009146 purine nucleoside triphosphate catabolic process
2.86 5.02e-03 GO:0006200 ATP catabolic process
1.84 5.07e-03 GO:0000087 M phase of mitotic cell cycle
1.92 5.52e-03 GO:0072523 purine-containing compound catabolic process
1.83 5.73e-03 GO:0048285 organelle fission
1.97 6.20e-03 GO:0009143 nucleoside triphosphate catabolic process
1.97 6.20e-03 GO:0009154 purine ribonucleotide catabolic process
1.25 6.96e-03 GO:0010468 regulation of gene expression
1.95 8.26e-03 GO:0009261 ribonucleotide catabolic process
1.27 8.39e-03 GO:0051252 regulation of RNA metabolic process
1.29 8.80e-03 GO:0043412 macromolecule modification
1.30 9.25e-03 GO:0006464 protein modification process
2.29 1.02e-02 GO:0045333 cellular respiration
2.82 1.11e-02 GO:0006405 RNA export from nucleus
1.23 1.13e-02 GO:0019538 protein metabolic process
1.26 1.19e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.59 1.24e-02 GO:0044265 cellular macromolecule catabolic process
1.90 1.25e-02 GO:0006195 purine nucleotide catabolic process
1.67 1.57e-02 GO:0016032 viral reproduction
1.80 1.83e-02 GO:0000280 nuclear division
1.80 1.83e-02 GO:0007067 mitosis
1.79 2.05e-02 GO:0009205 purine ribonucleoside triphosphate metabolic process
1.59 2.10e-02 GO:0034613 cellular protein localization
1.24 2.25e-02 GO:0009058 biosynthetic process
1.78 2.31e-02 GO:0009199 ribonucleoside triphosphate metabolic process
1.67 2.57e-02 GO:0006163 purine nucleotide metabolic process
1.71 2.65e-02 GO:0051301 cell division
1.52 2.69e-02 GO:0009057 macromolecule catabolic process
1.58 2.72e-02 GO:0070727 cellular macromolecule localization
1.77 2.91e-02 GO:0009144 purine nucleoside triphosphate metabolic process
1.33 2.94e-02 GO:0009056 catabolic process
2.18 3.11e-02 GO:0022900 electron transport chain
1.74 3.26e-02 GO:0009150 purine ribonucleotide metabolic process
1.62 4.91e-02 GO:0072521 purine-containing compound metabolic process
1.80 4.93e-02 GO:0009166 nucleotide catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.22 6.26e-51 GO:0005622 intracellular
1.23 8.52e-48 GO:0044424 intracellular part
1.26 1.35e-40 GO:0043226 organelle
1.26 1.56e-40 GO:0043229 intracellular organelle
1.45 8.94e-40 GO:0005634 nucleus
1.29 3.37e-39 GO:0043231 intracellular membrane-bounded organelle
1.29 3.47e-39 GO:0043227 membrane-bounded organelle
1.61 1.36e-20 GO:0044428 nuclear part
1.43 1.48e-19 GO:0032991 macromolecular complex
1.31 2.92e-18 GO:0044446 intracellular organelle part
1.74 2.84e-17 GO:0005654 nucleoplasm
1.29 3.75e-17 GO:0044422 organelle part
1.60 2.88e-16 GO:0031981 nuclear lumen
1.20 1.36e-15 GO:0005737 cytoplasm
1.49 3.42e-14 GO:0070013 intracellular organelle lumen
1.47 9.33e-14 GO:0031974 membrane-enclosed lumen
1.47 2.87e-13 GO:0043233 organelle lumen
1.37 2.34e-11 GO:0043234 protein complex
1.46 2.71e-11 GO:0005829 cytosol
1.78 1.07e-09 GO:0044451 nucleoplasm part
1.81 1.27e-07 GO:0005694 chromosome
1.19 2.21e-07 GO:0044444 cytoplasmic part
1.82 3.59e-07 GO:0030529 ribonucleoprotein complex
1.32 4.24e-07 GO:0043228 non-membrane-bounded organelle
1.32 4.24e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.83 1.55e-06 GO:0044427 chromosomal part
2.68 3.54e-06 GO:0044455 mitochondrial membrane part
1.64 1.03e-05 GO:0015630 microtubule cytoskeleton
1.43 1.61e-05 GO:0005739 mitochondrion
2.27 1.69e-05 GO:0005819 spindle
1.90 1.90e-05 GO:0005815 microtubule organizing center
2.47 1.35e-04 GO:0016607 nuclear speck
2.78 3.64e-04 GO:0031461 cullin-RING ubiquitin ligase complex
2.25 7.52e-04 GO:0000151 ubiquitin ligase complex
1.93 1.76e-03 GO:0016604 nuclear body
1.89 3.98e-03 GO:0005813 centrosome
2.69 7.64e-03 GO:0070469 respiratory chain
1.04 8.18e-03 GO:0044464 cell part
1.04 8.47e-03 GO:0005623 cell
3.07 1.24e-02 GO:0017053 transcriptional repressor complex
2.63 2.70e-02 GO:0005746 mitochondrial respiratory chain
2.71 4.40e-02 GO:0034708 methyltransferase complex
2.71 4.40e-02 GO:0035097 histone methyltransferase complex
3.84 4.84e-02 GO:0019005 SCF ubiquitin ligase complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.25 1.06e-19 GO:0005515 protein binding
1.42 6.75e-17 GO:0003676 nucleic acid binding
1.12 2.75e-13 GO:0005488 binding
1.37 4.11e-08 GO:0003677 DNA binding
1.63 4.95e-07 GO:0003723 RNA binding
1.84 8.42e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.72 1.47e-03 GO:0003712 transcription cofactor activity
1.71 1.64e-03 GO:0000988 protein binding transcription factor activity
1.71 1.64e-03 GO:0000989 transcription factor binding transcription factor activity
1.81 4.82e-03 GO:0016881 acid-amino acid ligase activity
1.27 5.85e-03 GO:0008270 zinc ion binding
1.24 7.13e-03 GO:0000166 nucleotide binding
1.95 8.16e-03 GO:0003682 chromatin binding
1.84 1.01e-02 GO:0019787 small conjugating protein ligase activity
1.36 3.06e-02 GO:0030528 transcription regulator activity
4.83 4.37e-02 GO:0030983 mismatched DNA binding