Motif ID: PAX5.p2

Z-value: 0.921


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_370343580.334.3e-01Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_101420004 0.767 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr2_-_46384 0.753 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr19_-_291168 0.731 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr1_-_1051458 0.617 C1orf159
chromosome 1 open reading frame 159
chr19_-_291335 0.554 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr15_+_101420032 0.549 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr3_-_132441216 0.529 NPHP3
nephronophthisis 3 (adolescent)
chr6_-_109804322 0.512 ZBTB24
zinc finger and BTB domain containing 24
chr14_-_105634708 0.503 JAG2
jagged 2
chr22_-_20255614 0.441 NM_023004
RTN4R
reticulon 4 receptor
chr16_-_68269948 0.440 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr22_-_43583132 0.437 NM_015140
TTLL12
tubulin tyrosine ligase-like family, member 12
chr1_+_117452359 0.433 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr5_-_60140041 0.431 NM_001104558
NM_024930
ELOVL7

ELOVL fatty acid elongase 7

chr2_+_47596286 0.426 NM_002354
EPCAM
epithelial cell adhesion molecule
chr2_+_47596447 0.413 EPCAM
epithelial cell adhesion molecule
chr16_-_17564737 0.405 NM_022166
XYLT1
xylosyltransferase I
chr17_+_30813928 0.403 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr6_-_109804432 0.391 NM_001164313
NM_014797
ZBTB24

zinc finger and BTB domain containing 24

chr4_-_819879 0.388 NM_006651
CPLX1
complexin 1
chr1_+_11333244 0.380 NM_013319
UBIAD1
UbiA prenyltransferase domain containing 1
chr17_+_55162530 0.380 NM_003488
AKAP1
A kinase (PRKA) anchor protein 1
chr2_+_112812799 0.372 NM_032824
TMEM87B
transmembrane protein 87B
chr3_-_57113292 0.361 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr17_-_41910439 0.352 NM_001932
MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr9_-_139137646 0.351 NM_181701
QSOX2
quiescin Q6 sulfhydryl oxidase 2
chr22_+_45148437 0.350 NM_001017526
NM_001198726
NM_181335
ARHGAP8


Rho GTPase activating protein 8


chr12_-_95044205 0.348 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr14_-_92302612 0.347 NM_001128595
NM_152332
TC2N

tandem C2 domains, nuclear

chr10_+_82213892 0.346 NM_001128309
NM_030927
TSPAN14

tetraspanin 14

chr15_-_52587851 0.338 NM_018728
MYO5C
myosin VC
chr14_-_95786095 0.335 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr6_+_37137882 0.334 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chrX_-_135056132 0.331 NM_173470
MMGT1
membrane magnesium transporter 1
chr2_-_27435014 0.330 NM_021095
SLC5A6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
chr1_-_160068359 0.329 NM_052868
IGSF8
immunoglobulin superfamily, member 8
chr15_-_68521921 0.329 NM_017882
CLN6
ceroid-lipofuscinosis, neuronal 6, late infantile, variant
chr8_+_86376130 0.325 NM_000067
CA2
carbonic anhydrase II
chr15_+_74833517 0.320 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr20_+_6748744 0.320 NM_001200
BMP2
bone morphogenetic protein 2
chr1_-_85358851 0.315 NM_012152
LPAR3
lysophosphatidic acid receptor 3
chr20_+_58152563 0.311 NM_001199505
PHACTR3
phosphatase and actin regulator 3
chr22_+_45098091 0.306 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr15_+_41136178 0.305 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr1_-_117210301 0.302 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr1_-_160068617 0.301 NM_001206665
IGSF8
immunoglobulin superfamily, member 8
chr1_+_955468 0.301 NM_198576
AGRN
agrin
chr5_+_68788387 0.300 NM_001205254
OCLN
occludin
chr1_-_175161832 0.297 NM_001162895
NM_014656
NM_001162893
NM_001162894
KIAA0040



KIAA0040



chr9_-_92112887 0.297 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr10_+_88516340 0.297 NM_004329
BMPR1A
bone morphogenetic protein receptor, type IA
chr4_+_154387450 0.296 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr22_-_43583058 0.295 TTLL12
tubulin tyrosine ligase-like family, member 12
chr22_+_26825220 0.294 NM_020437
ASPHD2
aspartate beta-hydroxylase domain containing 2
chr4_+_2794811 0.291 SH3BP2
SH3-domain binding protein 2
chr21_+_18885296 0.289 CXADR
coxsackie virus and adenovirus receptor
chr10_+_82214066 0.284 TSPAN14
tetraspanin 14
chr1_+_62208091 0.281 NM_176877
INADL
InaD-like (Drosophila)
chr2_-_235405692 0.279 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr1_-_160068261 0.279 IGSF8
immunoglobulin superfamily, member 8
chr1_+_46713433 0.278 RAD54L
RAD54-like (S. cerevisiae)
chr8_-_41166931 0.275 NM_003012
SFRP1
secreted frizzled-related protein 1
chr1_+_46713385 0.273 RAD54L
RAD54-like (S. cerevisiae)
chr7_-_98030165 0.272 BAIAP2L1
BAI1-associated protein 2-like 1
chr1_+_233463513 0.272 NM_032435
KIAA1804
mixed lineage kinase 4
chr1_+_43996478 0.270 NM_002840
NM_130440
PTPRF

protein tyrosine phosphatase, receptor type, F

chr8_-_127570710 0.270 NM_174911
FAM84B
family with sequence similarity 84, member B
chr4_+_85504056 0.269 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr1_+_46713359 0.266 NM_001142548
NM_003579
RAD54L

RAD54-like (S. cerevisiae)

chr17_-_3599298 0.265 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr5_-_1524022 0.265 NM_024830
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr10_+_82214071 0.264 TSPAN14
tetraspanin 14
chr1_+_35247838 0.262 NM_001005752
GJB3
gap junction protein, beta 3, 31kDa
chr1_-_48462561 0.260 NM_001194986
LOC388630
UPF0632 protein A
chr8_+_25042066 0.258 DOCK5
dedicator of cytokinesis 5
chr17_-_17726855 0.257 SREBF1
sterol regulatory element binding transcription factor 1
chr17_-_3599359 0.256 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr11_-_19263144 0.256 E2F8
E2F transcription factor 8
chr14_-_38064176 0.256 FOXA1
forkhead box A1
chr1_-_85462622 0.254 NM_153259
MCOLN2
mucolipin 2
chr2_-_20424627 0.249 NM_002997
SDC1
syndecan 1
chr5_-_1882764 0.249 NM_016358
IRX4
iroquois homeobox 4
chr11_-_19262424 0.249 NM_024680
E2F8
E2F transcription factor 8
chr14_-_105635114 0.248 NM_002226
NM_145159
JAG2

jagged 2

chr8_+_1712011 0.247 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr19_-_15090349 0.247 SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr4_+_1005395 0.244 FGFRL1
fibroblast growth factor receptor-like 1
chr16_+_67233013 0.242 NM_024712
ELMO3
engulfment and cell motility 3
chr16_-_3030391 0.242 PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
chr21_+_47649066 0.242 MCM3AP-AS1
MCM3AP antisense RNA 1 (non-protein coding)
chr5_-_139726173 0.237 NM_001945
HBEGF
heparin-binding EGF-like growth factor
chr15_+_75494235 0.237 C15orf39
chromosome 15 open reading frame 39
chr11_+_68079999 0.237 NM_002335
LRP5
low density lipoprotein receptor-related protein 5
chr10_-_133109983 0.236 NM_174937
TCERG1L
transcription elongation regulator 1-like
chr2_+_173292306 0.235 NM_000210
NM_001079818
ITGA6

integrin, alpha 6

chr8_+_120220554 0.235 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr2_-_9143742 0.234 NM_138799
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr21_-_43373938 0.232 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr2_-_20425166 0.229 NM_001006946
SDC1
syndecan 1
chr1_+_955609 0.229 AGRN
agrin
chr2_-_99347430 0.228 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr21_+_18885104 0.228 NM_001207063
NM_001207064
NM_001207065
NM_001207066
NM_001338
CXADR




coxsackie virus and adenovirus receptor




chr2_+_62423260 0.226 NM_006577
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
chr7_-_559479 0.226 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr1_+_11333502 0.225 UBIAD1
UbiA prenyltransferase domain containing 1
chr1_-_94147201 0.222 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr2_+_173292344 0.221 ITGA6
integrin, alpha 6
chr21_-_46293598 0.221 PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr7_+_18126543 0.221 NM_001204144
HDAC9
histone deacetylase 9
chr20_-_23618382 0.220 NM_000099
CST3
cystatin C
chr14_-_38064440 0.217 NM_004496
FOXA1
forkhead box A1
chr21_-_46293609 0.217 NM_004339
PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr21_-_46293532 0.214 PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr10_+_82214074 0.212 TSPAN14
tetraspanin 14
chr7_+_5322553 0.212 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr1_+_18434236 0.211 NM_032880
IGSF21
immunoglobin superfamily, member 21
chr6_-_11044354 0.211 NM_017770
ELOVL2
ELOVL fatty acid elongase 2
chr2_-_129076045 0.209 NM_004807
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr18_+_29078026 0.209 NM_001943
DSG2
desmoglein 2
chr4_+_1005609 0.209 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr1_-_9884024 0.208 CLSTN1
calsyntenin 1
chr8_+_28351694 0.208 NM_017412
NM_145866
FZD3

frizzled family receptor 3

chr7_-_105752718 0.208 NM_182715
SYPL1
synaptophysin-like 1
chr20_-_56284945 0.208 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr10_-_100027943 0.206 NM_032211
LOXL4
lysyl oxidase-like 4
chr6_-_99395774 0.205 FBXL4
F-box and leucine-rich repeat protein 4
chr21_-_46293561 0.205 PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr22_-_50946020 0.203 LMF2
lipase maturation factor 2
chr5_-_77944341 0.203 NM_005779
LHFPL2
lipoma HMGIC fusion partner-like 2
chr2_+_148602050 0.203 ACVR2A
activin A receptor, type IIA
chr1_+_210111575 0.203 SYT14
synaptotagmin XIV
chr6_+_138188352 0.203 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr19_+_45312294 0.202 NM_001013257
NM_005581
BCAM

basal cell adhesion molecule (Lutheran blood group)

chr20_+_61273786 0.201 NM_016354
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr20_+_61273823 0.201 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr15_+_75494233 0.199 C15orf39
chromosome 15 open reading frame 39
chr8_+_25042254 0.198 NM_024940
DOCK5
dedicator of cytokinesis 5
chr2_-_198175324 0.198 ANKRD44
ankyrin repeat domain 44
chr21_+_46293925 0.197


chr6_-_138428477 0.196 NM_022121
PERP
PERP, TP53 apoptosis effector
chr3_+_113666544 0.195 NM_173570
ZDHHC23
zinc finger, DHHC-type containing 23
chr1_-_202936333 0.195 NM_016243
CYB5R1
cytochrome b5 reductase 1
chr6_+_14117857 0.194 NM_001040280
NM_004233
CD83

CD83 molecule

chr6_+_4776826 0.193 CDYL
chromodomain protein, Y-like
chr6_+_4136242 0.192 LOC100507506
uncharacterized LOC100507506
chr1_+_227058241 0.191 NM_000447
NM_012486
PSEN2

presenilin 2 (Alzheimer disease 4)

chr7_-_138665853 0.190 NM_001164665
NM_020910
KIAA1549

KIAA1549

chr3_-_46735133 0.190 NM_001190707
NM_147129
ALS2CL

ALS2 C-terminal like

chr13_+_26042965 0.189 ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr15_+_90744506 0.189 NM_198925
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr22_-_50946129 0.189 NM_033200
LMF2
lipase maturation factor 2
chr1_+_222791151 0.189 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr1_-_9884549 0.188 NM_001009566
NM_014944
CLSTN1

calsyntenin 1

chr3_-_124931562 0.188 NM_024628
SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr8_-_144650998 0.188 C8orf73
chromosome 8 open reading frame 73
chr1_+_44584521 0.187 NM_173484
KLF17
Kruppel-like factor 17
chr17_-_74497406 0.187 NM_024599
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chrX_-_152989822 0.187 NM_005745
BCAP31
B-cell receptor-associated protein 31
chr17_-_3599487 0.186 NM_001204519
NM_001204520
NM_002561
NM_175080
P2RX5-TAX1BP3
P2RX5



P2RX5-TAX1BP3 readthrough
purinergic receptor P2X, ligand-gated ion channel, 5



chr15_+_73976621 0.184 NM_001024736
NM_025240
CD276

CD276 molecule

chr22_+_45064323 0.184 NM_001017528
NM_001017529
PRR5

proline rich 5 (renal)

chr16_+_67465019 0.183 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr6_-_99395807 0.183 NM_012160
FBXL4
F-box and leucine-rich repeat protein 4
chr21_-_16437125 0.183 NM_003489
NRIP1
nuclear receptor interacting protein 1
chr10_-_116164514 0.182 NM_001001936
NM_032550
AFAP1L2

actin filament associated protein 1-like 2

chr3_+_31574431 0.181 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr15_+_75494196 0.181 NM_015492
C15orf39
chromosome 15 open reading frame 39
chr4_-_37687932 0.181 NM_001085399
NM_001085400
RELL1

RELT-like 1

chr1_-_11714738 0.179 NM_012168
FBXO2
F-box protein 2
chr11_-_113345841 0.179 NM_000795
NM_016574
DRD2

dopamine receptor D2

chr6_+_12012723 0.178 NM_002114
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr19_-_7939325 0.176 NM_001190467
FLJ22184
putative uncharacterized protein FLJ22184
chr17_-_31203889 0.176 NM_015194
MYO1D
myosin ID
chr4_+_106816593 0.176 NM_001033047
NM_001184690
NM_001184691
NM_001184692
NM_001184693
NPNT




nephronectin




chr13_+_26042917 0.175 ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr2_+_233562042 0.175 GIGYF2
GRB10 interacting GYF protein 2
chr1_-_53793743 0.174 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr19_+_30302861 0.174 NM_001238
CCNE1
cyclin E1
chr1_+_116519175 0.174 SLC22A15
solute carrier family 22, member 15
chr6_-_39197225 0.173 NM_003740
KCNK5
potassium channel, subfamily K, member 5
chr4_+_103422730 0.173 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr6_+_14118002 0.172 CD83
CD83 molecule
chr1_+_65613211 0.171 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr20_+_62328068 0.170 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr16_-_87903028 0.170 NM_003486
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr9_+_22447064 0.170


chr15_+_41136622 0.169 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr7_-_105752650 0.167 SYPL1
synaptophysin-like 1
chr2_-_70781146 0.166 NM_001099691
NM_003236
TGFA

transforming growth factor, alpha

chr22_+_29279573 0.165 NM_001206998
ZNRF3
zinc and ring finger 3
chr9_-_100954883 0.165 NM_052820
CORO2A
coronin, actin binding protein, 2A
chr9_-_23821808 0.163 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_-_143105897 0.162 NM_005232
EPHA1
EPH receptor A1
chr20_+_59827452 0.162 NM_001794
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr3_-_133748828 0.162 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr1_+_955536 0.162


chr3_-_123603144 0.162 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr11_+_121322848 0.161 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr18_+_47088400 0.160 NM_006033
LIPG
lipase, endothelial
chr7_+_26331611 0.160 SNX10
sorting nexin 10

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.09 6.93e-21 GO:0009987 cellular process
1.13 1.06e-14 GO:0050794 regulation of cellular process
1.12 4.96e-14 GO:0065007 biological regulation
1.18 5.06e-14 GO:0044260 cellular macromolecule metabolic process
1.12 1.48e-13 GO:0050789 regulation of biological process
1.14 2.38e-13 GO:0044237 cellular metabolic process
1.11 1.98e-10 GO:0008152 metabolic process
1.26 5.98e-10 GO:0006464 protein modification process
1.12 2.20e-09 GO:0044238 primary metabolic process
1.18 3.81e-09 GO:0051179 localization
1.25 4.00e-09 GO:0043412 macromolecule modification
1.14 4.67e-09 GO:0043170 macromolecule metabolic process
1.26 1.85e-08 GO:0023051 regulation of signaling
1.17 1.93e-08 GO:0016043 cellular component organization
1.17 5.99e-08 GO:0071840 cellular component organization or biogenesis
1.19 6.36e-08 GO:0048518 positive regulation of biological process
1.28 7.97e-08 GO:0009966 regulation of signal transduction
1.20 1.47e-07 GO:0044267 cellular protein metabolic process
1.20 2.58e-07 GO:0048522 positive regulation of cellular process
1.17 9.59e-07 GO:0051234 establishment of localization
1.20 1.58e-06 GO:0048523 negative regulation of cellular process
1.17 2.04e-06 GO:0006810 transport
1.29 5.46e-06 GO:0010646 regulation of cell communication
1.18 2.29e-05 GO:0048519 negative regulation of biological process
1.14 2.48e-05 GO:0031323 regulation of cellular metabolic process
1.23 2.56e-05 GO:0007399 nervous system development
1.13 1.12e-04 GO:0019222 regulation of metabolic process
1.24 1.26e-04 GO:0051641 cellular localization
1.16 1.36e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.16 1.51e-04 GO:0071842 cellular component organization at cellular level
1.34 1.65e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.18 2.91e-04 GO:0065008 regulation of biological quality
1.14 2.95e-04 GO:0060255 regulation of macromolecule metabolic process
1.13 3.82e-04 GO:0080090 regulation of primary metabolic process
1.47 3.91e-04 GO:0060284 regulation of cell development
1.18 6.09e-04 GO:0048583 regulation of response to stimulus
1.14 7.16e-04 GO:0019538 protein metabolic process
1.13 9.35e-04 GO:0006807 nitrogen compound metabolic process
1.44 1.08e-03 GO:0018193 peptidyl-amino acid modification
1.14 1.27e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 1.36e-03 GO:0006468 protein phosphorylation
1.15 1.68e-03 GO:0009058 biosynthetic process
1.13 2.39e-03 GO:0034641 cellular nitrogen compound metabolic process
1.16 2.96e-03 GO:0048869 cellular developmental process
1.12 3.37e-03 GO:0023052 signaling
1.11 3.85e-03 GO:0032502 developmental process
1.49 3.87e-03 GO:0050767 regulation of neurogenesis
1.14 4.26e-03 GO:0009889 regulation of biosynthetic process
1.27 4.79e-03 GO:0051128 regulation of cellular component organization
1.26 4.86e-03 GO:0008219 cell death
1.45 5.35e-03 GO:0001944 vasculature development
1.14 5.48e-03 GO:0031326 regulation of cellular biosynthetic process
1.26 5.64e-03 GO:0016265 death
1.33 7.73e-03 GO:0009967 positive regulation of signal transduction
1.20 8.77e-03 GO:0033036 macromolecule localization
1.22 1.01e-02 GO:0051649 establishment of localization in cell
1.33 1.03e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.16 1.06e-02 GO:0030154 cell differentiation
1.12 1.08e-02 GO:0007165 signal transduction
1.14 1.20e-02 GO:0044249 cellular biosynthetic process
1.23 1.28e-02 GO:0006793 phosphorus metabolic process
1.23 1.28e-02 GO:0006796 phosphate metabolic process
1.57 1.34e-02 GO:0051272 positive regulation of cellular component movement
1.59 1.35e-02 GO:0001666 response to hypoxia
1.72 1.41e-02 GO:0010720 positive regulation of cell development
1.44 1.64e-02 GO:0001568 blood vessel development
1.15 1.67e-02 GO:0090304 nucleic acid metabolic process
1.81 1.79e-02 GO:0050769 positive regulation of neurogenesis
1.58 2.19e-02 GO:0031344 regulation of cell projection organization
1.11 2.23e-02 GO:0007275 multicellular organismal development
1.23 2.24e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.28 2.31e-02 GO:0030030 cell projection organization
1.27 2.35e-02 GO:0045595 regulation of cell differentiation
1.70 2.44e-02 GO:0032956 regulation of actin cytoskeleton organization
1.63 2.50e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.24 2.54e-02 GO:0048699 generation of neurons
1.43 2.60e-02 GO:0051960 regulation of nervous system development
1.23 2.79e-02 GO:0022008 neurogenesis
1.79 2.82e-02 GO:0006665 sphingolipid metabolic process
1.18 2.92e-02 GO:0009653 anatomical structure morphogenesis
1.20 2.93e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.63 2.93e-02 GO:0010975 regulation of neuron projection development
1.10 3.22e-02 GO:0051716 cellular response to stimulus
1.23 3.22e-02 GO:0048468 cell development
1.37 3.44e-02 GO:0016568 chromatin modification
1.62 3.51e-02 GO:0022604 regulation of cell morphogenesis
1.73 4.20e-02 GO:0006643 membrane lipid metabolic process
1.13 4.30e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.13 4.45e-02 GO:0010468 regulation of gene expression
1.43 4.69e-02 GO:0009100 glycoprotein metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 1.67e-30 GO:0043227 membrane-bounded organelle
1.14 4.02e-30 GO:0043231 intracellular membrane-bounded organelle
1.10 3.87e-29 GO:0005622 intracellular
1.10 1.09e-28 GO:0044424 intracellular part
1.12 4.25e-27 GO:0043226 organelle
1.12 2.02e-26 GO:0043229 intracellular organelle
1.14 8.92e-25 GO:0005737 cytoplasm
1.16 1.85e-18 GO:0044444 cytoplasmic part
1.04 2.28e-17 GO:0005623 cell
1.04 3.21e-17 GO:0044464 cell part
1.16 4.03e-16 GO:0044446 intracellular organelle part
1.34 8.58e-16 GO:0012505 endomembrane system
1.15 1.61e-15 GO:0044422 organelle part
1.14 1.43e-12 GO:0005634 nucleus
1.25 6.05e-12 GO:0031090 organelle membrane
1.35 9.19e-10 GO:0005794 Golgi apparatus
1.43 2.14e-08 GO:0044431 Golgi apparatus part
1.21 2.23e-08 GO:0044428 nuclear part
1.46 4.79e-08 GO:0000139 Golgi membrane
1.19 1.26e-06 GO:0070013 intracellular organelle lumen
1.19 1.31e-06 GO:0043233 organelle lumen
1.18 1.64e-06 GO:0031974 membrane-enclosed lumen
1.20 6.94e-06 GO:0031981 nuclear lumen
1.31 8.44e-05 GO:0015630 microtubule cytoskeleton
1.52 1.40e-04 GO:0005635 nuclear envelope
1.24 2.14e-04 GO:0005783 endoplasmic reticulum
1.16 4.11e-04 GO:0005829 cytosol
1.26 7.61e-04 GO:0005626 insoluble fraction
1.27 7.75e-04 GO:0044432 endoplasmic reticulum part
1.28 1.25e-03 GO:0005789 endoplasmic reticulum membrane
1.20 1.31e-03 GO:0005654 nucleoplasm
1.21 1.71e-03 GO:0000267 cell fraction
1.27 2.09e-03 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.25 2.56e-03 GO:0005624 membrane fraction
1.26 3.97e-03 GO:0031967 organelle envelope
1.26 4.27e-03 GO:0031975 envelope
1.57 6.21e-03 GO:0031965 nuclear membrane
1.35 1.96e-02 GO:0005815 microtubule organizing center
1.37 2.62e-02 GO:0005874 microtubule
1.51 2.99e-02 GO:0005912 adherens junction
1.48 3.33e-02 GO:0070161 anchoring junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 9.91e-19 GO:0005515 protein binding
1.07 6.35e-13 GO:0005488 binding
1.19 1.42e-06 GO:0000166 nucleotide binding
1.33 8.97e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.36 9.82e-06 GO:0004672 protein kinase activity
1.21 1.00e-05 GO:0016740 transferase activity
1.10 4.36e-05 GO:0003824 catalytic activity
1.30 6.02e-05 GO:0016301 kinase activity
1.27 6.90e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.18 1.60e-04 GO:0017076 purine nucleotide binding
1.18 1.91e-04 GO:0032553 ribonucleotide binding
1.18 1.91e-04 GO:0032555 purine ribonucleotide binding
1.64 2.42e-04 GO:0005085 guanyl-nucleotide exchange factor activity
1.18 3.59e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.19 1.01e-03 GO:0030554 adenyl nucleotide binding
1.18 1.46e-03 GO:0032559 adenyl ribonucleotide binding
1.27 1.62e-03 GO:0019899 enzyme binding
1.18 3.03e-03 GO:0005524 ATP binding
1.34 4.05e-03 GO:0004674 protein serine/threonine kinase activity
1.25 9.77e-03 GO:0042802 identical protein binding
1.31 1.18e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.31 1.62e-02 GO:0030695 GTPase regulator activity
1.37 2.53e-02 GO:0016564 transcription repressor activity
2.94 3.34e-02 GO:0032129 histone deacetylase activity (H3-K9 specific)
2.94 3.34e-02 GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
2.21 4.67e-02 GO:0008378 galactosyltransferase activity