Motif ID: POU2F1..3.p2

Z-value: 1.120


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F1chr1_+_1672983820.902.2e-03Click!
POU2F2chr19_-_426365590.782.2e-02Click!
POU2F3chr11_+_120107348,
chr11_+_120110902
-0.413.2e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_11779279 2.139 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chrX_-_24665454 1.499 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr5_+_36608430 1.445 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr18_-_53089722 1.252 NM_001243233
TCF4
transcription factor 4
chrX_-_24665225 1.152 PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr10_-_98031154 1.132 NM_001114094
NM_013314
BLNK

B-cell linker

chr6_+_26124372 1.099 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr10_-_123356158 1.081 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr17_-_56494889 1.059 RNF43
ring finger protein 43
chr9_-_140196702 1.042 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr1_+_206730456 1.015 NM_182665
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr12_-_31479120 1.014 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr12_-_31479084 0.994 FAM60A
family with sequence similarity 60, member A
chr12_+_107712151 0.976 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chrX_-_117119282 0.961 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr12_-_31479038 0.950 FAM60A
family with sequence similarity 60, member A
chr9_-_117160748 0.944 AKNA
AT-hook transcription factor
chr20_+_62795773 0.943 MYT1
myelin transcription factor 1
chr6_+_27215479 0.927 NM_005865
PRSS16
protease, serine, 16 (thymus)
chr17_-_56494930 0.911 NM_017763
RNF43
ring finger protein 43
chr6_+_26183957 0.904 NM_003523
HIST1H2BE
histone cluster 1, H2be
chr7_+_16793320 0.879 NM_014399
TSPAN13
tetraspanin 13
chr6_-_99797530 0.878 NM_032511
C6orf168
chromosome 6 open reading frame 168
chr1_+_206730497 0.835 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr11_+_34642587 0.818 NM_001206615
NM_012153
EHF

ets homologous factor

chr8_+_56792345 0.752 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr8_+_56792392 0.742 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr7_-_41742666 0.740 NM_002192
INHBA
inhibin, beta A
chr6_-_26124130 0.736 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr12_+_113344738 0.733 NM_001032409
NM_002534
NM_016816
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr8_+_56792399 0.719 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr1_+_156119734 0.709 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr5_+_145317297 0.695 SH3RF2
SH3 domain containing ring finger 2
chr4_-_40517913 0.672 NM_019027
RBM47
RNA binding motif protein 47
chr1_-_228645517 0.668 NM_033445
HIST3H2A
histone cluster 3, H2a
chr6_+_37137882 0.665 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr6_-_170599568 0.642 NM_005618
DLL1
delta-like 1 (Drosophila)
chr2_+_207804277 0.627 NM_173077
CPO
carboxypeptidase O
chr1_+_6052699 0.601 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr6_+_26251826 0.598 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr3_+_186648273 0.598 NM_173216
NM_173217
ST6GAL1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

chr16_+_23847271 0.592 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr1_+_6052758 0.584 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr2_-_113594325 0.579 NM_000576
IL1B
interleukin 1, beta
chrX_+_69674914 0.542 NM_001166278
DLG3
discs, large homolog 3 (Drosophila)
chr6_+_43139201 0.537 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr12_+_113344811 0.524 OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr6_-_27114577 0.518 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr6_-_27100528 0.513 NM_021058
HIST1H2BJ
histone cluster 1, H2bj
chr6_-_143266283 0.511 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr8_+_86099909 0.511 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chr13_+_97794050 0.500 MBNL2
muscleblind-like 2 (Drosophila)
chr11_+_64073040 0.483 NM_004451
ESRRA
estrogen-related receptor alpha
chr8_+_123793988 0.473 ZHX2
zinc fingers and homeoboxes 2
chr21_-_32201926 0.468 NM_181606
KRTAP7-1
keratin associated protein 7-1 (gene/pseudogene)
chr12_-_57328044 0.463 NM_148897
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr2_-_165551178 0.458 COBLL1
COBL-like 1
chr6_-_10415438 0.457 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr17_-_7307413 0.443 NM_152766
C17orf61-PLSCR3
C17orf61
C17orf61-PLSCR3 readthrough
chromosome 17 open reading frame 61
chr12_-_50616425 0.407 NM_001113547
LIMA1
LIM domain and actin binding 1
chr16_+_23847321 0.397 PRKCB
protein kinase C, beta
chr1_-_94586678 0.395 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr8_+_123793894 0.390 NM_014943
ZHX2
zinc fingers and homeoboxes 2
chr6_+_26158332 0.383 NM_021063
NM_138720
HIST1H2BD

histone cluster 1, H2bd

chr1_+_149822627 0.382 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr1_-_149814264 0.377 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr6_+_43139190 0.369 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr17_+_9745847 0.369 GLP2R
glucagon-like peptide 2 receptor
chr1_-_154832187 0.358 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr19_-_1132109 0.354 NM_001100122
SBNO2
strawberry notch homolog 2 (Drosophila)
chr1_-_149399159 0.350 NM_001024599
HIST2H2BF
histone cluster 2, H2bf
chr11_+_34642651 0.349 EHF
ets homologous factor
chr22_+_22758538 0.345


chr4_+_5526882 0.344 NM_005750
C4orf6
chromosome 4 open reading frame 6
chr1_-_149783910 0.342 NM_001024599
NM_001161334
HIST2H2BF

histone cluster 2, H2bf

chr1_+_167298382 0.326 POU2F1
POU class 2 homeobox 1
chr7_+_50348255 0.321 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chrX_-_84634742 0.318 NM_024921
POF1B
premature ovarian failure, 1B
chr2_+_202047620 0.314 NM_001206524
NM_001206542
NM_001230
NM_032974
NM_032976
NM_032977
CASP10





caspase 10, apoptosis-related cysteine peptidase





chr1_-_149859465 0.314 NM_175065
HIST2H2AB
HIST2H2BE
histone cluster 2, H2ab
histone cluster 2, H2be
chr8_+_123794043 0.309 ZHX2
zinc fingers and homeoboxes 2
chr17_+_7554239 0.305 NM_001678
ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr2_+_97426571 0.301 NM_020184
CNNM4
cyclin M4
chr6_+_26273143 0.298 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr19_+_19144617 0.291 ARMC6
armadillo repeat containing 6
chr5_+_166711842 0.291 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr3_+_127641901 0.289 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chrX_+_38660653 0.287 NM_001098790
NM_001098791
MID1IP1

MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))

chr7_+_94292737 0.287 PEG10
paternally expressed 10
chr2_-_46747095 0.284 NM_080653
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr3_+_132036276 0.282 ACPP
acid phosphatase, prostate
chr19_+_19144520 0.279 ARMC6
armadillo repeat containing 6
chr16_-_74808699 0.277 NM_024306
FA2H
fatty acid 2-hydroxylase
chr8_-_15095791 0.275 NM_139167
SGCZ
sarcoglycan, zeta
chr2_-_152684933 0.274 ARL5A
ADP-ribosylation factor-like 5A
chr7_+_18535351 0.268 NM_001204145
NM_001204146
NM_014707
NM_178423
HDAC9



histone deacetylase 9



chr2_-_237172987 0.268 NM_212556
ASB18
ankyrin repeat and SOCS box containing 18
chr1_+_81771844 0.264 LPHN2
latrophilin 2
chr22_+_24033047 0.264 NM_153615
RGL4
ral guanine nucleotide dissociation stimulator-like 4
chr18_-_52988916 0.264 NM_001243234
NM_001243235
TCF4

transcription factor 4

chr20_+_9198036 0.263 NM_182797
PLCB4
phospholipase C, beta 4
chr22_+_21986968 0.262 NM_152612
CCDC116
coiled-coil domain containing 116
chr11_+_27062508 0.262 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr2_+_202047803 0.257 CASP10
caspase 10, apoptosis-related cysteine peptidase
chr12_-_11139510 0.255 NM_176890
TAS2R50
taste receptor, type 2, member 50
chr19_+_41305100 0.254 EGLN2
egl nine homolog 2 (C. elegans)
chr3_+_132036210 0.254 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate

chr17_+_7554415 0.253 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr3_+_151591428 0.252 NM_033050
SUCNR1
succinate receptor 1
chr16_-_74808474 0.251 FA2H
fatty acid 2-hydroxylase
chr7_-_141673572 0.248 NM_176817
TAS2R38
taste receptor, type 2, member 38
chrX_+_38660692 0.248 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr6_-_26216871 0.246 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr3_-_165555167 0.246 BCHE
butyrylcholinesterase
chr2_+_16080559 0.244 MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr11_+_112047088 0.244 NM_001037290
BCO2
beta-carotene oxygenase 2
chr1_-_149858114 0.244 NM_003528
HIST2H2BE
histone cluster 2, H2be
chr6_-_138820580 0.242


chr19_+_41305041 0.242 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr11_-_62369213 0.241 MTA2
metastasis associated 1 family, member 2
chr2_-_215896809 0.241 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr12_-_6484389 0.238 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chrX_-_131547536 0.236 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr19_+_19144370 0.235 NM_001199196
NM_033415
ARMC6

armadillo repeat containing 6

chr12_-_48963802 0.235 NM_002289
LALBA
lactalbumin, alpha-
chr10_+_123922940 0.228 TACC2
transforming, acidic coiled-coil containing protein 2
chr15_-_64995346 0.227 OAZ2
ornithine decarboxylase antizyme 2
chr2_-_152684689 0.226 ARL5A
ADP-ribosylation factor-like 5A
chr1_-_186649421 0.222 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr12_-_11062160 0.221 NM_023920
TAS2R13
taste receptor, type 2, member 13
chr6_+_27861202 0.220 NM_003527
HIST1H2BO
histone cluster 1, H2bo
chrX_-_84634664 0.220 POF1B
premature ovarian failure, 1B
chr6_-_43655514 0.219 MRPS18A
mitochondrial ribosomal protein S18A
chr14_+_65007418 0.219 HSPA2
heat shock 70kDa protein 2
chr19_-_50169021 0.218 NM_001197122
NM_001197123
NM_001197124
NM_001197125
NM_001197126
NM_001197127
NM_001197128
NM_001571
IRF3







interferon regulatory factor 3







chr12_+_122064448 0.217 NM_032790
ORAI1
ORAI calcium release-activated calcium modulator 1
chr6_-_43655539 0.214 NM_001193343
NM_018135
MRPS18A

mitochondrial ribosomal protein S18A

chr11_-_62369097 0.213 MTA2
metastasis associated 1 family, member 2
chr19_+_50169080 0.210 BCL2L12
BCL2-like 12 (proline rich)
chr22_+_32750871 0.209 NM_006604
RFPL3
ret finger protein-like 3
chr10_-_62332666 0.209 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr19_+_17337012 0.207 NM_024578
OCEL1
occludin/ELL domain containing 1
chr11_-_64084980 0.206 NM_016404
TRMT112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr9_-_2844098 0.205 NM_014878
KIAA0020
KIAA0020
chr14_-_23445885 0.204 AJUBA
ajuba LIM protein
chr19_-_40791291 0.201 NM_001243027
NM_001243028
NM_001626
AKT2


v-akt murine thymoma viral oncogene homolog 2


chr9_-_3223007 0.200


chr11_+_46383115 0.199 NM_001105540
DGKZ
diacylglycerol kinase, zeta
chr3_+_50192420 0.198 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_-_165555252 0.197 NM_000055
BCHE
butyrylcholinesterase
chr11_-_62358969 0.196 NM_022830
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chr11_-_62369250 0.194 NM_004739
MTA2
metastasis associated 1 family, member 2
chr10_-_97321094 0.194 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr11_-_115375065 0.193 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr1_+_41157241 0.193 NM_001142587
NM_001142588
NM_001142589
NM_014223
NFYC



nuclear transcription factor Y, gamma



chr19_-_50168866 0.193 IRF3
interferon regulatory factor 3
chr6_-_138820578 0.192 NM_001144060
NHSL1
NHS-like 1
chr14_+_65007163 0.191 NM_021979
HSPA2
heat shock 70kDa protein 2
chr18_+_77866914 0.190 NM_014913
ADNP2
ADNP homeobox 2
chr17_-_48072566 0.187 NM_005220
DLX3
distal-less homeobox 3
chr1_+_228645807 0.186 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr11_-_3013550 0.185 NAP1L4
nucleosome assembly protein 1-like 4
chr9_-_2844083 0.184 KIAA0020
KIAA0020
chr10_+_123923104 0.180 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr11_+_537521 0.179 NM_198075
LRRC56
leucine rich repeat containing 56
chr19_-_19281090 0.178 NM_001145785
MEF2B
myocyte enhancer factor 2B
chr16_-_30107492 0.178 NM_031477
NM_001145524
YPEL3

yippee-like 3 (Drosophila)

chr10_+_106113513 0.178 NM_001008723
CCDC147
coiled-coil domain containing 147
chr7_-_100183753 0.177 NM_002319
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr4_-_47983430 0.177 NM_001142564
CNGA1
cyclic nucleotide gated channel alpha 1
chr1_+_167298280 0.176 NM_001198783
POU2F1
POU class 2 homeobox 1
chr6_+_31588460 0.175 PRRC2A
proline-rich coiled-coil 2A
chr1_-_68962679 0.174 DEPDC1
DEP domain containing 1
chr15_-_40600065 0.174 PLCB2
phospholipase C, beta 2
chr19_-_19281062 0.174 MEF2B
myocyte enhancer factor 2B
chr10_-_72648540 0.173 NM_000281
PCBD1
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chrX_+_123234462 0.173 STAG2
stromal antigen 2
chr7_-_44122083 0.170 POLM
polymerase (DNA directed), mu
chr7_-_44122036 0.169 POLM
polymerase (DNA directed), mu
chr6_-_134373618 0.168 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr3_-_121379701 0.168 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr6_+_143999058 0.166 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr22_+_23054862 0.165 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr7_+_16566504 0.164 NM_001195280
LRRC72
leucine rich repeat containing 72
chr18_-_24442534 0.163 NM_004028
AQP4
aquaporin 4
chr21_-_39493349 0.161 NM_005867
DSCR4
Down syndrome critical region gene 4
chr6_+_31588444 0.161 NM_004638
NM_080686
PRRC2A

proline-rich coiled-coil 2A

chr18_+_44526786 0.161 NM_031303
KATNAL2
katanin p60 subunit A-like 2
chr2_+_16080639 0.160 NM_005378
MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr18_+_76740274 0.160 NM_171999
SALL3
sal-like 3 (Drosophila)
chr5_-_142065586 0.159 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr5_-_2751768 0.158 NM_001134222
NM_033267
IRX2

iroquois homeobox 2

chr6_+_148663953 0.157 SASH1
SAM and SH3 domain containing 1
chr5_+_52776408 0.156 FST
follistatin
chr8_+_26435590 0.155 DPYSL2
dihydropyrimidinase-like 2
chr5_+_52776263 0.155 NM_006350
NM_013409
FST

follistatin

chr19_+_41305333 0.152 NM_053046
EGLN2
egl nine homolog 2 (C. elegans)
chr6_+_31588524 0.152 PRRC2A
proline-rich coiled-coil 2A
chr6_+_148663728 0.152 NM_015278
SASH1
SAM and SH3 domain containing 1
chr13_-_70682458 0.151 NM_020866
KLHL1
kelch-like 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
8.13 1.28e-10 GO:0034728 nucleosome organization
8.58 1.69e-10 GO:0006334 nucleosome assembly
8.14 4.90e-10 GO:0031497 chromatin assembly
7.40 8.94e-10 GO:0071824 protein-DNA complex subunit organization
7.45 2.84e-09 GO:0065004 protein-DNA complex assembly
6.43 4.83e-09 GO:0006333 chromatin assembly or disassembly
5.87 3.19e-08 GO:0071103 DNA conformation change
6.22 9.09e-08 GO:0006323 DNA packaging
2.13 2.76e-05 GO:0002376 immune system process
2.49 4.63e-05 GO:0006955 immune response
3.16 2.01e-04 GO:0034622 cellular macromolecular complex assembly
2.81 2.07e-04 GO:0034621 cellular macromolecular complex subunit organization
2.85 2.41e-04 GO:0006325 chromatin organization
1.31 3.64e-03 GO:0050896 response to stimulus
12.46 8.11e-03 GO:0050853 B cell receptor signaling pathway
2.34 8.38e-03 GO:0051276 chromosome organization
1.68 9.32e-03 GO:0048513 organ development
2.16 1.31e-02 GO:0071844 cellular component assembly at cellular level
7.34 1.62e-02 GO:0050909 sensory perception of taste
2.08 1.73e-02 GO:0006952 defense response
4.67 3.46e-02 GO:0050851 antigen receptor-mediated signaling pathway
1.50 4.26e-02 GO:0048518 positive regulation of biological process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
12.50 5.03e-14 GO:0000786 nucleosome
7.89 4.93e-10 GO:0032993 protein-DNA complex
4.29 1.91e-07 GO:0000785 chromatin
2.34 2.31e-03 GO:0005694 chromosome
2.43 4.41e-03 GO:0044427 chromosomal part
1.45 2.01e-02 GO:0043228 non-membrane-bounded organelle
1.45 2.01e-02 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
8.88 1.57e-04 GO:0003823 antigen binding
2.64 1.52e-02 GO:0003779 actin binding
2.15 3.62e-02 GO:0008092 cytoskeletal protein binding