Motif ID: PPARG.p2

Z-value: 0.479


Transcription factors associated with PPARG.p2:

Gene SymbolEntrez IDGene Name
PPARG 5468 peroxisome proliferator-activated receptor gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PPARGchr3_+_12329332,
chr3_+_12392993,
chr3_+_12330336
-0.157.2e-01Click!


Activity profile for motif PPARG.p2.

activity profile for motif PPARG.p2


Sorted Z-values histogram for motif PPARG.p2

Sorted Z-values for motif PPARG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PPARG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_203274646 0.461 NM_006763
BTG2
BTG family, member 2
chr10_-_116418056 0.301 NM_002313
ABLIM1
actin binding LIM protein 1
chr15_+_57998920 0.240 POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr15_+_57998853 0.237 NM_001018102
NM_015532
POLR2M

polymerase (RNA) II (DNA directed) polypeptide M

chr7_+_75932865 0.168 HSPB1
heat shock 27kDa protein 1
chr1_+_16083132 0.161 FBLIM1
filamin binding LIM protein 1
chr7_+_75932992 0.156 HSPB1
heat shock 27kDa protein 1
chr15_-_74753490 0.154 NM_032907
NM_201265
UBL7

ubiquitin-like 7 (bone marrow stromal cell-derived)

chr15_-_74753431 0.151 UBL7
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr8_-_101118170 0.150 RGS22
regulator of G-protein signaling 22
chr14_+_24630421 0.146 NM_006084
IRF9
interferon regulatory factor 9
chr8_-_70745403 0.143 NM_001146009
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr10_-_99052429 0.136 NM_001204300
NM_032900
ARHGAP19

Rho GTPase activating protein 19

chr8_-_145642226 0.131 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr1_-_160254910 0.129 PEX19
peroxisomal biogenesis factor 19
chr16_+_90168671 0.127 FAM157C
family with sequence similarity 157, member C
chr22_+_22758538 0.123


chr10_-_99052358 0.123 ARHGAP19
Rho GTPase activating protein 19
chr10_-_99052391 0.121 ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough
Rho GTPase activating protein 19
chr12_+_109915461 0.121 UBE3B
ubiquitin protein ligase E3B
chr8_-_145642250 0.120 NM_130849
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr11_+_313852 0.113 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr1_-_160254923 0.108 NM_001193644
NM_002857
PEX19

peroxisomal biogenesis factor 19

chr8_-_127570710 0.101 NM_174911
FAM84B
family with sequence similarity 84, member B
chr19_+_7968762 0.100 MAP2K7
mitogen-activated protein kinase kinase 7
chr19_+_7968765 0.099 MAP2K7
mitogen-activated protein kinase kinase 7
chr8_-_9009050 0.095 NM_001201329
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr3_+_8775485 0.090 NM_001234
NM_033337
CAV3

caveolin 3

chr6_+_159309618 0.089 NM_001195032
C6orf99
chromosome 6 open reading frame 99
chr19_+_18451365 0.086 NM_017712
PGPEP1
pyroglutamyl-peptidase I
chr19_+_7968820 0.085 MAP2K7
mitogen-activated protein kinase kinase 7
chr11_+_117070039 0.082 NM_001001522
NM_003186
TAGLN

transgelin

chr19_+_4343523 0.081 NM_001159846
NM_032868
MPND

MPN domain containing

chr11_-_63933204 0.081 MACROD1
MACRO domain containing 1
chr1_-_151762905 0.079 NM_001083963
NM_001083964
NM_001083965
NM_006862
TDRKH



tudor and KH domain containing



chr11_-_118016134 0.075 NM_001142349
SCN4B
sodium channel, voltage-gated, type IV, beta
chr11_-_1330680 0.075 TOLLIP
toll interacting protein
chr11_+_46740736 0.075 NM_000506
F2
coagulation factor II (thrombin)
chr11_-_64052123 0.074 BAD
BCL2-associated agonist of cell death
chr9_-_33447527 0.073 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr15_-_76603728 0.071 ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr17_+_48172100 0.071 NM_001199898
PDK2
pyruvate dehydrogenase kinase, isozyme 2
chr14_+_100531745 0.071 NM_016337
EVL
Enah/Vasp-like
chr11_+_46740769 0.070 F2
coagulation factor II (thrombin)
chr19_-_51017124 0.070 NM_001114598
ASPDH
aspartate dehydrogenase domain containing
chr19_+_1383904 0.068 NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr19_+_7968764 0.067 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr9_+_34329503 0.067 NM_001161
NM_001244390
NM_147172
NM_147173
NUDT2



nudix (nucleoside diphosphate linked moiety X)-type motif 2



chr12_-_6484904 0.065 NM_001038
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr15_-_83621350 0.065 NM_004839
NM_199330
HOMER2

homer homolog 2 (Drosophila)

chr12_+_109915446 0.065 UBE3B
ubiquitin protein ligase E3B
chr7_-_128543379 0.064 KCP
kielin/chordin-like protein
chr11_+_308106 0.063 NM_006435
IFITM2
interferon induced transmembrane protein 2 (1-8D)
chr8_-_97247757 0.062 NM_001199975
NM_006294
UQCRB

ubiquinol-cytochrome c reductase binding protein

chr12_+_109915430 0.061 NM_130466
NM_183415
UBE3B

ubiquitin protein ligase E3B

chr1_-_3816823 0.059 NM_207356
C1orf174
chromosome 1 open reading frame 174
chr19_+_1491000 0.059 NM_138393
REEP6
receptor accessory protein 6
chr15_-_76603742 0.059 ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr1_-_3816704 0.058 C1orf174
chromosome 1 open reading frame 174
chr11_+_2923528 0.058 SLC22A18
solute carrier family 22, member 18
chr16_+_8768403 0.058 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr15_-_76603791 0.057 ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr15_-_76603806 0.056 NM_000126
NM_001127716
ETFA

electron-transfer-flavoprotein, alpha polypeptide

chr17_+_7942351 0.056 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr1_-_38218573 0.055 EPHA10
EPH receptor A10
chr1_+_153388999 0.053 NM_176823
S100A7A
S100 calcium binding protein A7A
chr3_+_49057907 0.053 NM_199074
NDUFAF3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr19_+_7968701 0.053 MAP2K7
mitogen-activated protein kinase kinase 7
chr22_-_29977325 0.053 NM_003634
NIPSNAP1
nipsnap homolog 1 (C. elegans)
chr19_+_50016606 0.052 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_+_2923559 0.052 SLC22A18
solute carrier family 22, member 18
chr2_-_42588300 0.052 NM_004718
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr8_-_127570465 0.048 FAM84B
family with sequence similarity 84, member B
chr11_+_117947726 0.045 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr11_+_75526211 0.044 NM_003369
UVRAG
UV radiation resistance associated gene
chr17_-_882905 0.043 NM_022463
NXN
nucleoredoxin
chr11_+_117947785 0.043 TMPRSS4
transmembrane protease, serine 4
chr11_-_1330883 0.041 TOLLIP
toll interacting protein
chr19_+_56152281 0.040 NM_207115
ZNF580
zinc finger protein 580
chr1_-_6551759 0.039 NM_020631
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr5_+_167956545 0.039


chrX_-_107019001 0.039 NM_198057
TSC22D3
TSC22 domain family, member 3
chr10_+_49514652 0.039 MAPK8
mitogen-activated protein kinase 8
chr2_+_47168362 0.039 TTC7A
tetratricopeptide repeat domain 7A
chr11_-_64052164 0.039 NM_004322
NM_032989
BAD

BCL2-associated agonist of cell death

chr3_+_33840060 0.038 NM_001162429
NM_013374
PDCD6IP

programmed cell death 6 interacting protein

chr1_-_24469571 0.038 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr19_+_48958765 0.037 NM_013348
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr1_-_94586678 0.036 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr2_-_72371188 0.036 CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr17_+_25958192 0.035 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_-_74236272 0.035 NM_052916
RNF157
ring finger protein 157
chr17_+_48172508 0.034 NM_001199900
NM_002611
NM_001199899
PDK2


pyruvate dehydrogenase kinase, isozyme 2


chr7_-_10979752 0.034 NM_002489
NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr11_-_63993340 0.034 NM_001160393
TRPT1
tRNA phosphotransferase 1
chr15_+_81517639 0.033 NM_172217
IL16
interleukin 16
chr11_+_75526236 0.033 UVRAG
UV radiation resistance associated gene
chr17_+_42248073 0.033 NM_080863
ASB16
ankyrin repeat and SOCS box containing 16
chr10_+_102758072 0.033 LZTS2
leucine zipper, putative tumor suppressor 2
chr17_-_39728304 0.032 NM_000226
KRT9
keratin 9
chr17_+_25958257 0.032 LGALS9
lectin, galactoside-binding, soluble, 9
chr2_-_203103214 0.032 NM_001005781
NM_001005782
NM_003352
SUMO1


SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)


chr1_-_68299047 0.032 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr9_+_140125208 0.032 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr8_-_30515665 0.031 NM_002095
GTF2E2
general transcription factor IIE, polypeptide 2, beta 34kDa
chr1_+_19923457 0.031 NM_001204088
NM_001204089
NM_001032363
NM_001204082
NM_001204083
C1orf151-NBL1

MINOS1


C1orf151-NBL1 readthrough

mitochondrial inner membrane organizing system 1


chrX_-_107018889 0.030 TSC22D3
TSC22 domain family, member 3
chr6_-_112575708 0.030 LAMA4
laminin, alpha 4
chr22_+_20008602 0.029 NM_152906
C22orf25
chromosome 22 open reading frame 25
chr17_-_40337384 0.029 NM_001524
HCRT
hypocretin (orexin) neuropeptide precursor
chrX_-_48828250 0.029 NM_004979
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr19_+_36239261 0.029 NM_019104
LIN37
lin-37 homolog (C. elegans)
chr11_-_320775 0.029 NM_021034
IFITM3
interferon induced transmembrane protein 3
chr1_+_217804665 0.028 NM_138796
SPATA17
spermatogenesis associated 17
chr6_+_132859426 0.028 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr1_+_33231260 0.027 KIAA1522
KIAA1522
chr20_-_44540685 0.027 PLTP
phospholipid transfer protein
chr8_-_143867931 0.027 NM_003695
LY6D
lymphocyte antigen 6 complex, locus D
chr19_+_751108 0.026 NM_173481
C19orf21
chromosome 19 open reading frame 21
chr17_-_41984888 0.026 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr20_+_816710 0.025 NM_207121
FAM110A
family with sequence similarity 110, member A
chr19_-_49944613 0.025 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr9_-_138591318 0.025 NM_001012415
NM_001101677
SOHLH1

spermatogenesis and oogenesis specific basic helix-loop-helix 1

chr7_-_10979683 0.024 NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr5_+_178977559 0.024 NM_025158
RUFY1
RUN and FYVE domain containing 1
chr7_-_141401889 0.024 NM_001080392
KIAA1147
KIAA1147
chr19_+_1383898 0.024 NDUFS7
NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr4_+_57371374 0.023 NM_206919
ARL9
ADP-ribosylation factor-like 9
chr17_-_38074842 0.023 NM_001042471
NM_001165958
NM_001165959
GSDMB


gasdermin B


chr11_+_7506599 0.023 NM_198474
OLFML1
olfactomedin-like 1
chr8_-_53626982 0.023 RB1CC1
RB1-inducible coiled-coil 1
chr10_+_102821552 0.023 KAZALD1
Kazal-type serine peptidase inhibitor domain 1
chr22_+_40390935 0.023 NM_138435
FAM83F
family with sequence similarity 83, member F
chr19_+_1000295 0.023 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr3_-_46505077 0.022 NM_001199149
LTF
lactotransferrin
chr2_+_220110184 0.022 NM_001008910
STK16
serine/threonine kinase 16
chr21_-_43771069 0.022 NM_005423
TFF2
trefoil factor 2
chr6_+_292033 0.022 NM_020185
DUSP22
dual specificity phosphatase 22
chr9_-_37592575 0.022 NM_001001790
NM_001134484
NM_001134485
TOMM5


translocase of outer mitochondrial membrane 5 homolog (yeast)


chr11_+_722282 0.022 EPS8L2
EPS8-like 2
chr14_-_92572950 0.021 NM_001127696
NM_001127697
NM_001164774
NM_001164776
NM_001164777
NM_001164778
NM_001164779
NM_001164780
NM_001164781
NM_001164782
NM_004993
NM_030660
ATXN3











ataxin 3











chr15_-_41120905 0.020 NM_001130143
NM_017726
PPP1R14D

protein phosphatase 1, regulatory (inhibitor) subunit 14D

chr1_+_16693582 0.020 NM_001114600
NM_015609
C1orf144

chromosome 1 open reading frame 144

chr12_-_53730003 0.020 NM_001173467
SP7
Sp7 transcription factor
chr15_+_74753602 0.020 LOC440288
uncharacterized LOC440288
chr12_-_117747214 0.020 NM_001204214
NOS1
nitric oxide synthase 1 (neuronal)
chr17_+_41177247 0.019 NM_005440
RND2
Rho family GTPase 2
chr19_+_42388445 0.019 NM_199002
ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr9_-_37592465 0.019 TOMM5
translocase of outer mitochondrial membrane 5 homolog (yeast)
chr22_+_20008633 0.019 C22orf25
chromosome 22 open reading frame 25
chr9_+_101984558 0.019 NM_006808
SEC61B
Sec61 beta subunit
chr1_-_47080793 0.019 NM_145279
MOB3C
MOB kinase activator 3C
chr11_-_1330840 0.019 TOLLIP
toll interacting protein
chr19_+_49128208 0.019 NM_001204160
SPHK2
sphingosine kinase 2
chr11_-_1330808 0.019 TOLLIP
toll interacting protein
chr13_-_28024700 0.018 NM_001166263
NM_152912
MTIF3

mitochondrial translational initiation factor 3

chr17_+_25958151 0.018 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr8_-_53626991 0.018 NM_001083617
NM_014781
RB1CC1

RB1-inducible coiled-coil 1

chr19_+_52873169 0.018 NM_001145434
ZNF880
zinc finger protein 880
chr15_-_85201793 0.018 NM_021077
NM_205858
NMB

neuromedin B

chr12_-_57118263 0.018 NACA
nascent polypeptide-associated complex alpha subunit
chr17_-_7531107 0.018 NM_133491
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr10_-_125651494 0.018 NM_198148
CPXM2
carboxypeptidase X (M14 family), member 2
chr17_-_76573475 0.018 NM_173628
DNAH17
dynein, axonemal, heavy chain 17
chr19_+_50016435 0.018 NM_004107
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr9_-_34458477 0.017 NM_001184940
NM_001184941
NM_001184942
NM_001184943
NM_001184945
NM_147202
C9orf25





chromosome 9 open reading frame 25





chr20_-_35374530 0.017 NM_022477
NM_032013
NDRG3

NDRG family member 3

chr14_-_75389144 0.017 NM_031464
RPS6KL1
ribosomal protein S6 kinase-like 1
chrX_-_51812249 0.017 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chr17_-_7297826 0.017 PLSCR3
phospholipid scramblase 3
chr16_-_3627353 0.017 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr11_-_8739398 0.017 ST5
suppression of tumorigenicity 5
chr2_+_70121074 0.017 NM_006857
SNRNP27
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr12_-_121476770 0.017 NM_003733
NM_198213
OASL

2'-5'-oligoadenylate synthetase-like

chr12_-_57504935 0.017 STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr22_+_20105076 0.016 RANBP1
RAN binding protein 1
chr20_-_35374468 0.016 NDRG3
NDRG family member 3
chr1_+_44435649 0.016 NM_001039589
NM_001384
DPH2

DPH2 homolog (S. cerevisiae)

chr9_-_130679210 0.016 NM_175039
NM_175040
ST6GALNAC4

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

chr1_+_29562947 0.016 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr1_+_150521786 0.016 NM_019032
NM_025008
ADAMTSL4

ADAMTS-like 4

chr6_-_26285726 0.016 NM_003543
HIST1H4H
histone cluster 1, H4h
chr11_+_2924504 0.016 SLC22A18
solute carrier family 22, member 18
chr22_+_23229959 0.016 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chrX_+_51927918 0.015 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chr6_-_43477980 0.015 LRRC73
leucine rich repeat containing 73
chr1_-_6526150 0.015 NM_001039664
NM_003790
NM_148965
NM_148966
NM_148967
NM_148970
TNFRSF25





tumor necrosis factor receptor superfamily, member 25





chr7_-_100425035 0.015 NM_004444
EPHB4
EPH receptor B4
chr19_+_50016500 0.015 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr14_-_106208695 0.015


chr15_+_69745156 0.015 NM_001003
NM_213725
RPLP1

ribosomal protein, large, P1

chr11_+_2923487 0.014 NM_002555
SLC22A18
solute carrier family 22, member 18
chr8_-_132052834 0.014 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr1_+_158323485 0.014 NM_001042583
NM_001042584
NM_001042585
NM_001042586
NM_001042587
NM_001185107
NM_001185108
NM_001185110
NM_001185112
NM_001185113
NM_001185114
NM_001185115
NM_030893
CD1E












CD1e molecule












chr6_+_97010423 0.013 NM_001170807
NM_020482
FHL5

four and a half LIM domains 5

chr20_+_55204307 0.013 NM_003222
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr1_+_14031349 0.013 NM_012231
NM_015866
PRDM2

PR domain containing 2, with ZNF domain

chr6_-_112575766 0.013 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr17_+_77704881 0.013 NM_178543
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr19_-_51587466 0.013 NM_022046
KLK14
kallikrein-related peptidase 14

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.36 4.38e-02 GO:0019221 cytokine-mediated signaling pathway

Nothing significant found in compartment category.

Nothing significant found in function category.