Motif ID: RORA.p2

Z-value: 0.623


Transcription factors associated with RORA.p2:

Gene SymbolEntrez IDGene Name
RORA 6095 RAR-related orphan receptor A

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RORAchr15_-_60884615-0.772.4e-02Click!


Activity profile for motif RORA.p2.

activity profile for motif RORA.p2


Sorted Z-values histogram for motif RORA.p2

Sorted Z-values for motif RORA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RORA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_136847743 1.601 NM_001198614
NM_001198618
NM_001198619
MAP7


microtubule-associated protein 7


chr15_+_40509628 1.419 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr11_-_120008801 1.039 TRIM29
tripartite motif containing 29
chr10_-_105845619 0.932 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr10_-_105845556 0.511 COL17A1
collagen, type XVII, alpha 1
chr6_+_43738757 0.447 VEGFA
vascular endothelial growth factor A
chr1_+_46640748 0.372 NM_005727
TSPAN1
tetraspanin 1
chr11_-_102651321 0.369 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr6_-_111927059 0.355 TRAF3IP2
TRAF3 interacting protein 2
chr5_-_134914968 0.329 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr2_-_216003068 0.324 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr6_+_43738394 0.323 VEGFA
vascular endothelial growth factor A
chr5_+_66124603 0.315 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr6_+_43737937 0.301 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_001204384
NM_001204385
NM_003376
VEGFA

















vascular endothelial growth factor A

















chr6_-_52109226 0.299 NM_052872
IL17F
interleukin 17F
chr18_+_55816546 0.299 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr6_+_15245702 0.291 JARID2
jumonji, AT rich interactive domain 2
chr1_+_158149736 0.281 NM_001766
CD1D
CD1d molecule
chr4_+_85504056 0.281 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr16_+_27325269 0.268 IL4R
interleukin 4 receptor
chr8_-_142238672 0.267 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr11_-_120008738 0.253 TRIM29
tripartite motif containing 29
chr6_+_37252166 0.252 TBC1D22B
TBC1 domain family, member 22B
chr17_-_35656691 0.250 NM_198837
NM_198838
ACACA

acetyl-CoA carboxylase alpha

chr7_-_107204705 0.250 NM_001161520
NM_006348
NM_181733
COG5


component of oligomeric golgi complex 5


chr7_+_18535351 0.248 NM_001204145
NM_001204146
NM_014707
NM_178423
HDAC9



histone deacetylase 9



chr12_+_50479033 0.240 SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr6_+_121756744 0.230 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr13_+_109248499 0.225 NM_015011
MYO16
myosin XVI
chr8_+_120220554 0.220 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr19_-_49140569 0.216 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr19_-_55580896 0.204 NM_138412
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr6_+_32121775 0.196 NM_001204103
NM_005155
PPT2-EGFL8
PPT2

PPT2-EGFL8 readthrough
palmitoyl-protein thioesterase 2

chr12_+_105153258 0.187 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr7_-_83824216 0.180 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_24536176 0.180 NM_000461
NM_001128176
NM_001128177
NM_001252634
THRB



thyroid hormone receptor, beta



chr11_+_107462073 0.179 ELMOD1
ELMO/CED-12 domain containing 1
chr8_-_95449131 0.173 NM_001205263
RAD54B
RAD54 homolog B (S. cerevisiae)
chr8_-_144654921 0.172 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chrX_-_32173585 0.152 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr6_+_32121228 0.152 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr17_-_48785016 0.140 NM_052855
ANKRD40
ankyrin repeat domain 40
chr1_+_67632168 0.138 NM_144701
IL23R
interleukin 23 receptor
chr6_-_111927082 0.137 TRAF3IP2
TRAF3 interacting protein 2
chr6_-_24383519 0.136 NM_001195610
DCDC2
doublecortin domain containing 2
chr9_+_125281418 0.134 NM_001004452
OR1J4
olfactory receptor, family 1, subfamily J, member 4
chr1_-_205744543 0.133 NM_001135662
NM_001135663
NM_001135664
NM_003929
RAB7L1



RAB7, member RAS oncogene family-like 1



chr7_+_97736118 0.125 NM_014916
LMTK2
lemur tyrosine kinase 2
chr6_+_43738177 0.123 VEGFA
vascular endothelial growth factor A
chr15_+_45422130 0.119 NM_017434
NM_175940
DUOX1

dual oxidase 1

chrX_-_33229428 0.116 NM_004006
DMD
dystrophin
chr19_-_7796977 0.116 NM_001244856
NM_198492
CLEC4G

C-type lectin domain family 4, member G

chr4_-_120243257 0.115 NM_000134
FABP2
fatty acid binding protein 2, intestinal
chr1_-_156786500 0.109 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr10_-_52645384 0.106 A1CF
APOBEC1 complementation factor
chr15_-_45422056 0.104 NM_144565
DUOXA1
dual oxidase maturation factor 1
chr2_-_165477986 0.093 GRB14
growth factor receptor-bound protein 14
chr4_-_151770611 0.092 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chrX_-_24690740 0.091 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr17_+_40996596 0.091 NM_001158
NM_009590
AOC2

amine oxidase, copper containing 2 (retina-specific)

chr10_-_21435487 0.091 NM_001010896
NM_001177483
C10orf113

chromosome 10 open reading frame 113

chr12_+_113376301 0.091 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr15_-_56535475 0.090 NM_022841
RFX7
regulatory factor X, 7
chr11_-_119599253 0.089 NM_002855
NM_203285
NM_203286
PVRL1


poliovirus receptor-related 1 (herpesvirus entry mediator C)


chr5_+_38258660 0.089 EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr16_-_12009918 0.088 GSPT1
G1 to S phase transition 1
chr12_+_113376001 0.084 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr11_+_107461807 0.076 NM_001130037
NM_018712
ELMOD1

ELMO/CED-12 domain containing 1

chr16_-_15188089 0.075 NM_018427
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr9_-_114545772 0.074 NM_173521
C9orf84
chromosome 9 open reading frame 84
chr7_+_129008044 0.074 AHCYL2
adenosylhomocysteinase-like 2
chr13_-_103719195 0.070 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chrX_-_2882288 0.069 NM_000047
ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr5_+_38258510 0.066 NM_001205301
NM_152403
EGFLAM

EGF-like, fibronectin type III and laminin G domains

chr6_-_134373618 0.066 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr10_-_72141347 0.065 NM_207119
LRRC20
leucine rich repeat containing 20
chr17_-_43502992 0.063 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chrX_-_10544852 0.063 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr5_-_137071703 0.060 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr1_+_31883020 0.058 NM_001199037
SERINC2
serine incorporator 2
chr7_+_150782881 0.057 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr14_-_24804243 0.057 NM_001198568
NM_001198592
NM_139247
ADCY4


adenylate cyclase 4


chr3_+_1134619 0.055 NM_014461
CNTN6
contactin 6
chr6_-_34101272 0.055 NM_000841
GRM4
glutamate receptor, metabotropic 4
chr11_-_72380107 0.054 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr6_-_155635611 0.053 NM_016020
TFB1M
transcription factor B1, mitochondrial
chr6_-_155635562 0.053 TFB1M
transcription factor B1, mitochondrial
chr17_-_17485691 0.051 PEMT
phosphatidylethanolamine N-methyltransferase
chr14_-_90798253 0.049 NM_017970
C14orf102
chromosome 14 open reading frame 102
chr18_+_63417845 0.048 CDH7
cadherin 7, type 2
chr17_-_17485744 0.048 NM_007169
PEMT
phosphatidylethanolamine N-methyltransferase
chr9_+_74920329 0.044


chr1_+_205782430 0.042


chr1_-_103496768 0.042 COL11A1
collagen, type XI, alpha 1
chr1_-_203155910 0.041 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr12_+_93963597 0.040 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr17_-_34308455 0.040 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr11_+_13299260 0.040 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr1_-_235812994 0.040 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr1_+_109255555 0.040 NM_001144937
FNDC7
fibronectin type III domain containing 7
chr11_+_13299329 0.038 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr3_+_32433342 0.038 CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr6_+_4836331 0.038 NM_001143970
CDYL
chromodomain protein, Y-like
chr18_-_3874688 0.037 NM_001242762
NM_001242763
DLGAP1

discs, large (Drosophila) homolog-associated protein 1

chr16_-_21831730 0.037 RRN3P1
RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
chr4_+_110749149 0.036 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr16_+_24266873 0.035 NM_006539
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr1_-_161147757 0.035 NM_001199873
NM_001199874
NM_003779
B4GALT3


UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3


chr7_+_129007942 0.035 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr17_-_3499124 0.035 NM_080705
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chrX_-_23925947 0.033 NM_024122
APOO
apolipoprotein O
chr6_-_152623213 0.032 SYNE1
spectrin repeat containing, nuclear envelope 1
chrX_+_119495939 0.031 NM_001142447
NM_012069
ATP1B4

ATPase, Na+/K+ transporting, beta 4 polypeptide

chr15_-_65670325 0.031 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr14_-_75389144 0.030 NM_031464
RPS6KL1
ribosomal protein S6 kinase-like 1
chr11_+_13299376 0.030 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_-_129062092 0.030 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr22_+_21771661 0.029 NM_015094
HIC2
hypermethylated in cancer 2
chr11_+_13299372 0.028 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr2_+_171034654 0.028 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr10_+_114043413 0.027 NM_058222
TECTB
tectorin beta
chr2_+_139259476 0.027


chr14_+_94492747 0.027 OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr22_+_21821458 0.026 NM_001207052
TMEM191C
transmembrane protein 191C
chr1_-_203155867 0.026 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr11_+_13299391 0.025 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr17_-_38859976 0.025 NM_019016
KRT24
keratin 24
chrX_+_65235279 0.025


chr7_+_115863004 0.025 NM_152829
TES
testis derived transcript (3 LIM domains)
chr2_+_102927961 0.025 NM_016232
IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chr14_-_75600111 0.023 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr1_-_150207025 0.023 NM_001136479
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr7_+_50348255 0.021 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr1_+_111833473 0.021 NM_021797
NM_201653
CHIA

chitinase, acidic

chr4_-_186732208 0.021 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr7_-_107880492 0.020 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr5_+_61708565 0.020 NM_016338
IPO11
importin 11
chr11_+_13299349 0.020 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr22_-_33402648 0.019 NM_003490
NM_133633
SYN3

synapsin III

chr17_+_32646058 0.019 NM_005623
CCL8
chemokine (C-C motif) ligand 8
chr17_+_7554711 0.019 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr6_+_143929316 0.019 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chrX_+_12924738 0.019 NM_138636
TLR8
toll-like receptor 8
chr17_+_26369935 0.017 NLK
nemo-like kinase
chr17_-_2304217 0.017 NM_020310
MNT
MAX binding protein
chr17_+_7533452 0.017 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr17_+_20978860 0.016


chr3_-_184095927 0.016 NM_000460
NM_001177597
NM_001177598
THPO


thrombopoietin


chr19_+_40146533 0.016 NM_001190441
LGALS16
lectin, galactoside-binding, soluble, 16
chr1_+_20396652 0.015 NM_000929
PLA2G5
phospholipase A2, group V
chr2_-_31030271 0.014 NM_144575
CAPN13
calpain 13
chr19_+_57791794 0.014 NM_006635
ZNF460
zinc finger protein 460
chr6_-_32634287 0.012 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chr19_+_8953268 0.012 NM_145208
MBD3L1
methyl-CpG binding domain protein 3-like 1
chr14_+_92788924 0.012 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_+_132318980 0.012 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chr10_-_52645430 0.012 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr19_-_8567473 0.012 NM_032152
PRAM1
PML-RARA regulated adaptor molecule 1
chr19_+_40093163 0.011 NM_013268
LGALS13
lectin, galactoside-binding, soluble, 13
chr8_-_6420454 0.011 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr1_-_47695442 0.010 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr16_+_16326478 0.010 NOMO2
NODAL modulator 2
chr1_-_203155827 0.010 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr7_+_120969089 0.010 NM_057168
WNT16
wingless-type MMTV integration site family, member 16
chr4_+_39408472 0.009 NM_175737
KLB
klotho beta
chr1_-_247697140 0.009 NM_198074
OR2C3
olfactory receptor, family 2, subfamily C, member 3
chr8_+_125463042 0.009 NM_017956
TRMT12
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr3_-_50360109 0.008 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr10_+_101542554 0.008 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr1_+_171750807 0.008 METTL13
methyltransferase like 13
chr5_-_175395544 0.007 NM_032361
THOC3
THO complex 3
chr6_-_30181197 0.007 NM_001242783
NM_003449
TRIM26

tripartite motif containing 26

chr1_-_151798552 0.007 NM_001001523
RORC
RAR-related orphan receptor C
chr1_-_120311466 0.007 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr1_-_173176314 0.007 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr10_+_102729249 0.006 SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr8_-_134072404 0.006 NM_006748
SLA
Src-like-adaptor
chr7_+_112063131 0.006 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr9_-_139292888 0.006 NM_003086
SNAPC4
small nuclear RNA activating complex, polypeptide 4, 190kDa
chr6_-_30128688 0.005 NM_006778
NM_052828
TRIM10

tripartite motif containing 10

chr1_+_197881618 0.005 NM_001014434
LHX9
LIM homeobox 9
chr1_-_211751953 0.005 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr7_-_42971779 0.005 NM_002787
PSMA2
proteasome (prosome, macropain) subunit, alpha type, 2
chr11_-_73720281 0.004 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr1_-_51810693 0.004 NM_001144832
TTC39A
tetratricopeptide repeat domain 39A
chr16_+_16326488 0.003 NOMO2
NODAL modulator 2
chr16_+_16326454 0.002 NOMO2
NODAL modulator 2
chr2_-_228497801 0.002 NM_001162483
NM_020161
C2orf83

chromosome 2 open reading frame 83

chr12_-_56848398 0.002 NM_012064
MIP
major intrinsic protein of lens fiber
chr10_-_121296044 0.001 NM_002925
RGS10
regulator of G-protein signaling 10
chr2_+_233243243 0.001 NM_001632
ALPP
alkaline phosphatase, placental
chr7_-_126883568 0.001 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr19_-_51220194 0.000 NM_016148
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr16_+_16326471 0.000 NOMO2
NODAL modulator 2
chr17_-_59940669 0.000 NM_032043
BRIP1
BRCA1 interacting protein C-terminal helicase 1
chr10_-_72362513 0.000 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr10_+_18041217 0.000 NM_001098844
TMEM236
transmembrane protein 236

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.58 4.09e-03 GO:0002376 immune system process

Nothing significant found in compartment category.

Nothing significant found in function category.