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Motif ID: RUNX1..3.p2

Z-value: 1.186

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_+_45067750	1.537	NM_003278	CLEC3B	C-type lectin domain family 3, member B
chr8_-_12973752	1.379	NM_001164271	DLC1	deleted in liver cancer 1
chr6_+_72926462	1.245	NM_001168410	RIMS1	regulating synaptic membrane exocytosis 1
chrX_+_9431314	1.126	NM_001139466 NM_001139467 NM_001139468	TBL1X	transducin (beta)-like 1X-linked
chr2_+_128175989	1.039	NM_000312	PROC	protein C (inactivator of coagulation factors Va and VIIIa)
chr2_+_33359607	0.925	NM_000627 NM_001166264 NM_001166265 NM_001166266	LTBP1	latent transforming growth factor beta binding protein 1
chr2_+_189839078	0.915	NM_000090	COL3A1	collagen, type III, alpha 1
chr9_-_95186559	0.904	NM_005014	OMD	osteomodulin
chr16_+_53133063	0.899		CHD9	chromodomain helicase DNA binding protein 9
chr8_-_60031545	0.853	NM_014729	TOX	thymocyte selection-associated high mobility group box
chr5_+_156696351	0.849	NM_014376	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr19_+_51226638	0.847		CLEC11A	C-type lectin domain family 11, member A
chr11_-_119293848	0.827		THY1	Thy-1 cell surface antigen
chr14_-_61115906	0.818	NM_005982	SIX1	SIX homeobox 1
chr9_+_120466607	0.772		TLR4	toll-like receptor 4
chr1_-_184006491	0.751		GLT25D2	glycosyltransferase 25 domain containing 2
chr5_+_139505519	0.749	NM_001007189	IGIP	IgA-inducing protein homolog (Bos taurus)
chr6_-_132272311	0.745	NM_001901	CTGF	connective tissue growth factor
chr2_+_128176019	0.736		PROC	protein C (inactivator of coagulation factors Va and VIIIa)
chr19_+_51226593	0.718	NM_002975	CLEC11A	C-type lectin domain family 11, member A
chr6_+_72926144	0.708	NM_001168409	RIMS1	regulating synaptic membrane exocytosis 1
chr9_+_120466625	0.704		TLR4	toll-like receptor 4
chr11_+_1889902	0.686	NM_001013253	LSP1	lymphocyte-specific protein 1
chr1_+_155853546	0.672		SYT11	synaptotagmin XI
chr10_+_31607419	0.660		ZEB1	zinc finger E-box binding homeobox 1
chr3_+_157154579	0.654	NM_002852	PTX3	pentraxin 3, long
chr10_+_70847817	0.648	NM_002727	SRGN	serglycin
chr2_+_189839132	0.642		COL3A1	collagen, type III, alpha 1
chr5_+_75699003	0.639	NM_006633	IQGAP2	IQ motif containing GTPase activating protein 2
chr1_-_16939687	0.630	NM_017940	NBPF1	neuroblastoma breakpoint family, member 1
chr4_+_126237566	0.596	NM_024582	FAT4	FAT tumor suppressor homolog 4 (Drosophila)
chr10_+_70847857	0.590		SRGN	serglycin
chr1_+_215178884	0.576	NM_001017424	KCNK2	potassium channel, subfamily K, member 2
chr5_-_38595506	0.561	NM_002310	LIFR	leukemia inhibitory factor receptor alpha
chr6_-_31514620	0.560	NM_001204078 NM_130463 NM_138282	ATP6V1G2	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr2_-_216300444	0.544		FN1	fibronectin 1
chr12_-_4754275	0.541	NM_006422	AKAP3	A kinase (PRKA) anchor protein 3
chr5_-_111091947	0.539	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr2_-_175462428	0.539		WIPF1	WAS/WASL interacting protein family, member 1
chr20_+_12989616	0.535	NM_018327	SPTLC3	serine palmitoyltransferase, long chain base subunit 3
chr17_-_43045612	0.529	NM_006688	C1QL1	complement component 1, q subcomponent-like 1
chr5_-_149535420	0.525	NM_002609	PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr21_-_36421630	0.523		RUNX1	runt-related transcription factor 1
chr12_+_13349716	0.521		EMP1	epithelial membrane protein 1
chrX_-_135863033	0.512		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr18_+_66465316	0.512	NM_024781	CCDC102B	coiled-coil domain containing 102B
chr2_-_200325200	0.511		SATB2	SATB homeobox 2
chrX_-_135863104	0.510		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr13_+_76210449	0.506		LMO7	LIM domain 7
chr9_-_130540911	0.501	NM_170600	SH2D3C	SH2 domain containing 3C
chr14_+_21152735	0.497		ANG RNASE4	angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4
chr6_-_35696359	0.493	NM_001145775	FKBP5	FK506 binding protein 5
chrX_-_135863502	0.492	NM_004840	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr16_+_67311412	0.480	NM_015432	PLEKHG4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr17_+_19281726	0.471	NM_002749 NM_139034	MAPK7	mitogen-activated protein kinase 7
chr4_-_76928601	0.470	NM_002416	CXCL9	chemokine (C-X-C motif) ligand 9
chr11_+_92702788	0.468	NM_005959	MTNR1B	melatonin receptor 1B
chr4_+_71091787	0.463	NM_152997	C4orf7	chromosome 4 open reading frame 7
chr11_+_6411637	0.457	NM_000543 NM_001007593	SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal
chr15_-_93631751	0.445	NM_001166287	RGMA	RGM domain family, member A
chr14_-_60097531	0.441	NM_206852	RTN1	reticulon 1
chr19_+_51226662	0.440		CLEC11A	C-type lectin domain family 11, member A
chr15_-_93632161	0.439	NM_020211	RGMA	RGM domain family, member A
chrX_-_106960028	0.433		TSC22D3	TSC22 domain family, member 3
chr2_-_158300517	0.432	NM_004288	CYTIP	cytohesin 1 interacting protein
chr9_-_73736513	0.426	NM_001007471	TRPM3	transient receptor potential cation channel, subfamily M, member 3
chr5_+_140753480	0.424	NM_018919 NM_032086	PCDHGA6	protocadherin gamma subfamily A, 6
chr1_+_183605207	0.422	NM_015149	RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr1_-_86043932	0.418	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr22_+_31003069	0.417	NM_000355 NM_001184726	TCN2	transcobalamin II
chr10_+_91092238	0.414	NM_001031683	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr3_-_187454247	0.409	NM_001130845	BCL6	B-cell CLL/lymphoma 6
chr14_-_24977421	0.408	NM_001836	CMA1	chymase 1, mast cell
chr20_-_45985411	0.408	NM_012408 NM_183047 NM_183048	ZMYND8	zinc finger, MYND-type containing 8
chr15_-_82336880	0.407		MEX3B	mex-3 homolog B (C. elegans)
chr11_-_67141647	0.406	NM_001166212	CLCF1	cardiotrophin-like cytokine factor 1
chr15_-_37393364	0.405	NM_001220482 NM_002399	MEIS2	Meis homeobox 2
chr17_-_29641068	0.396		EVI2B	ecotropic viral integration site 2B
chr17_-_29641087	0.393		EVI2B	ecotropic viral integration site 2B
chr8_+_1952875	0.391		KBTBD11	kelch repeat and BTB (POZ) domain containing 11
chr17_+_19281013	0.388	NM_139032 NM_139033	MAPK7	mitogen-activated protein kinase 7
chr1_+_174843523	0.387	NM_001243763	RABGAP1L	RAB GTPase activating protein 1-like
chr3_-_150920946	0.385	NM_013308	GPR171	G protein-coupled receptor 171
chr6_+_155538096	0.384	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chr22_+_35695267	0.384	NM_001135729	TOM1	target of myb1 (chicken)
chr20_+_31595513	0.384		BPIFB2	BPI fold containing family B, member 2
chr11_-_67141008	0.373	NM_013246	CLCF1	cardiotrophin-like cytokine factor 1
chr8_-_19540093	0.371	NM_018371	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr15_-_55652777	0.370		CCPG1	cell cycle progression 1
chrX_+_103031797	0.370		PLP1	proteolipid protein 1
chr4_-_156787377	0.369	NM_017419	ACCN5	amiloride-sensitive cation channel 5, intestinal
chr5_+_119799898	0.369		PRR16	proline rich 16
chr19_+_14544216	0.368		PKN1	protein kinase N1
chr17_-_34524054	0.368	NM_001001437 NM_021006	CCL3L3 CCL3 CCL3L1	chemokine (C-C motif) ligand 3-like 3 chemokine (C-C motif) ligand 3 chemokine (C-C motif) ligand 3-like 1
chr3_-_114343052	0.365	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr12_-_15038724	0.360	NM_000900 NM_001190839	MGP	matrix Gla protein
chrX_-_106960268	0.360	NM_004089	TSC22D3	TSC22 domain family, member 3
chr7_-_56160604	0.357	NM_006213	PHKG1	phosphorylase kinase, gamma 1 (muscle)
chr1_+_196621007	0.355	NM_000186 NM_001014975	CFH	complement factor H
chr15_-_34875060	0.353		GOLGA8B	golgin A8 family, member B
chr4_+_145567147	0.352	NM_022475	HHIP	hedgehog interacting protein
chr7_-_50861114	0.349	NM_001001555	GRB10	growth factor receptor-bound protein 10
chr13_-_38172862	0.349	NM_001135934 NM_001135935 NM_001135936 NM_006475	POSTN	periostin, osteoblast specific factor
chr17_-_29641094	0.348	NM_006495	EVI2B	ecotropic viral integration site 2B
chr6_-_13295817	0.346	NM_001242698	LOC100130357	uncharacterized LOC100130357
chr11_-_5462782	0.346	NM_001005288	OR51I1	olfactory receptor, family 51, subfamily I, member 1
chr3_+_141043054	0.344	NM_001080412	ZBTB38	zinc finger and BTB domain containing 38
chr7_+_28448970	0.341		LOC401317	uncharacterized LOC401317
chr8_-_38326351	0.335	NM_001174063 NM_001174064 NM_015850 NM_023105 NM_023106 NM_023110	FGFR1	fibroblast growth factor receptor 1
chr19_+_2289996	0.334
chrX_+_22050920	0.332	NM_000444	PHEX	phosphate regulating endopeptidase homolog, X-linked
chrX_-_15872938	0.332		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr7_+_154720154	0.330		LOC100132707	uncharacterized LOC100132707
chr5_-_111093030	0.329	NM_001142482 NM_001142481	C5orf13	chromosome 5 open reading frame 13
chr2_+_228678556	0.329	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chrX_-_40036581	0.327	NM_001123383 NM_001123384	BCOR	BCL6 corepressor
chr14_-_75078669	0.327	NM_000428	LTBP2	latent transforming growth factor beta binding protein 2
chr12_+_69139958	0.325		SLC35E3	solute carrier family 35, member E3
chr2_-_216300770	0.323	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chrX_-_15872882	0.323		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr19_+_50015535	0.320	NM_001136019	FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr5_-_111092918	0.318	NM_004772	C5orf13	chromosome 5 open reading frame 13
chr7_-_141646716	0.318	NM_013252	CLEC5A	C-type lectin domain family 5, member A
chr1_+_152850797	0.317	NM_030663	SMCP	sperm mitochondria-associated cysteine-rich protein
chr19_-_14048877	0.315		PODNL1	podocan-like 1
chr18_-_25756946	0.314		CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr1_+_183774214	0.314		RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr12_-_112819755	0.313	NM_001109662	C12orf51	chromosome 12 open reading frame 51
chr13_-_28674646	0.309	NM_004119	FLT3	fms-related tyrosine kinase 3
chr12_-_58026846	0.308	NM_001478	B4GALNT1	beta-1,4-N-acetyl-galactosaminyl transferase 1
chr1_-_9117554	0.305		SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr11_-_6643809	0.304		DCHS1	dachsous 1 (Drosophila)
chr5_+_76248679	0.304	NM_001882	CRHBP	corticotropin releasing hormone binding protein
chr20_+_31595377	0.301	NM_025227	BPIFB2	BPI fold containing family B, member 2
chr10_-_65028825	0.299	NM_004241	JMJD1C	jumonji domain containing 1C
chr12_+_69139917	0.298	NM_018656	SLC35E3	solute carrier family 35, member E3
chr1_+_32930638	0.295	NM_001145720	ZBTB8B	zinc finger and BTB domain containing 8B
chrX_+_47441650	0.294	NM_003254	TIMP1	TIMP metallopeptidase inhibitor 1
chr3_+_42947401	0.292	NM_207404	ZNF662	zinc finger protein 662
chr20_-_1600589	0.289	NM_001083910 NM_001135844 NM_006065	SIRPB1	signal-regulatory protein beta 1
chrX_+_51546154	0.287	NM_001005332	MAGED1	melanoma antigen family D, 1
chr16_+_29674564	0.287		SPN	sialophorin
chr15_+_89631380	0.283	NM_007011 NM_152924	ABHD2	abhydrolase domain containing 2
chr1_+_164528586	0.282	NM_001204961 NM_001204963 NM_002585	PBX1	pre-B-cell leukemia homeobox 1
chr2_-_207082626	0.279	NM_001098199 NM_005279	GPR1	G protein-coupled receptor 1
chr5_+_59784004	0.276		PART1	prostate androgen-regulated transcript 1 (non-protein coding)
chr17_-_1531543	0.276		SLC43A2	solute carrier family 43, member 2
chr17_-_15165800	0.274		PMP22	peripheral myelin protein 22
chr7_-_50860665	0.272		GRB10	growth factor receptor-bound protein 10
chr14_-_88460008	0.271	NM_001201402	GALC	galactosylceramidase
chr19_-_14049167	0.270	NM_024825	PODNL1	podocan-like 1
chr4_+_8951476	0.268	NM_001040071	LOC650293	seven transmembrane helix receptor
chr22_+_39378404	0.268	NM_004900	APOBEC3D APOBEC3B	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
chr1_+_6615337	0.265	NM_138697 NM_177540	TAS1R1	taste receptor, type 1, member 1
chr17_+_56232493	0.264	NM_012374	OR4D1	olfactory receptor, family 4, subfamily D, member 1
chr2_+_136499466	0.264		UBXN4	UBX domain protein 4
chr14_-_23822025	0.264	NM_016609	SLC22A17	solute carrier family 22, member 17
chr19_+_50015868	0.263		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr3_+_98250742	0.262	NM_005290	GPR15	G protein-coupled receptor 15
chr3_-_45267068	0.262		TMEM158	transmembrane protein 158 (gene/pseudogene)
chr6_-_30710219	0.261	NM_005803	FLOT1	flotillin 1
chr20_+_31595454	0.259		BPIFB2	BPI fold containing family B, member 2
chr15_+_44069272	0.257	NM_001199877	SERF2	small EDRK-rich factor 2
chr11_+_118868841	0.256	NM_198489	CCDC84	coiled-coil domain containing 84
chr1_-_161039413	0.255		ARHGAP30	Rho GTPase activating protein 30
chr17_-_76921076	0.255		TIMP2	TIMP metallopeptidase inhibitor 2
chr2_-_211018294	0.254		C2orf67	chromosome 2 open reading frame 67
chr17_-_1532109	0.253	NM_152346	SLC43A2	solute carrier family 43, member 2
chr9_+_34652125	0.249	NM_001142784	IL11RA	interleukin 11 receptor, alpha
chr5_+_119800004	0.248	NM_016644	PRR16	proline rich 16
chr1_+_218518675	0.248	NM_001135599 NM_003238	TGFB2	transforming growth factor, beta 2
chr1_+_145727712	0.247		PDZK1	PDZ domain containing 1
chr1_+_145727665	0.247	NM_001201325 NM_001201326 NM_002614	PDZK1	PDZ domain containing 1
chr17_-_48264039	0.246		COL1A1	collagen, type I, alpha 1
chr9_-_130517552	0.245	NM_001142534 NM_001142533	SH2D3C	SH2 domain containing 3C
chr17_-_48278874	0.245		COL1A1	collagen, type I, alpha 1
chr2_-_214015053	0.244	NM_016260	IKZF2	IKAROS family zinc finger 2 (Helios)
chr2_+_201980929	0.244		CFLAR	CASP8 and FADD-like apoptosis regulator
chr17_+_44076615	0.242	NM_001007532	STH	saitohin
chr12_+_56075418	0.242		METTL7B	methyltransferase like 7B
chr4_-_113437327	0.242	NM_024019	NEUROG2	neurogenin 2
chr7_+_2552162	0.241	NM_001166355	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_+_56075329	0.240	NM_152637	METTL7B	methyltransferase like 7B
chr3_+_42947649	0.240	NM_001134656	ZNF662	zinc finger protein 662
chrX_-_15872905	0.239
chr3_+_156008775	0.239	NM_172159	KCNAB1	potassium voltage-gated channel, shaker-related subfamily, beta member 1
chrX_+_103031433	0.238	NM_001128834	PLP1	proteolipid protein 1
chr3_+_42704598	0.238		ZBTB47	zinc finger and BTB domain containing 47
chr3_+_46619075	0.237	NM_003212	TDGF1	teratocarcinoma-derived growth factor 1
chr7_-_44228880	0.235	NM_000162	GCK	glucokinase (hexokinase 4)
chr17_+_64298844	0.234	NM_002737	PRKCA	protein kinase C, alpha
chr2_-_230579198	0.233	NM_139072	DNER	delta/notch-like EGF repeat containing
chr2_+_169659099	0.231	NM_001039724 NM_001171632 NM_052946	NOSTRIN	nitric oxide synthase trafficker
chr22_+_22020272	0.230	NM_014337 NM_148175 NM_148176	PPIL2	peptidylprolyl isomerase (cyclophilin)-like 2
chr2_-_71221951	0.229		TEX261	testis expressed 261
chr11_+_118868861	0.228		CCDC84	coiled-coil domain containing 84
chr3_-_71180061	0.227	NM_001244815	FOXP1	forkhead box P1
chrX_+_103031753	0.227	NM_000533 NM_199478	PLP1	proteolipid protein 1
chr22_-_24640850	0.226	NM_001099781 NM_001099782 NM_004121	GGT5	gamma-glutamyltransferase 5
chr11_-_10715297	0.225		MRVI1	murine retrovirus integration site 1 homolog

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.79	5.48e-03	GO:0001775	cell activation
1.47	1.00e-02	GO:0002376	immune system process
1.23	2.45e-02	GO:0023052	signaling
1.24	4.56e-02	GO:0007165	signal transduction
1.51	4.73e-02	GO:0009611	response to wounding

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.52	6.83e-04	GO:0044421	extracellular region part
1.57	2.40e-03	GO:0005615	extracellular space
1.42	4.54e-03	GO:0031226	intrinsic to plasma membrane
1.42	6.65e-03	GO:0005887	integral to plasma membrane
1.30	6.78e-03	GO:0044459	plasma membrane part
1.31	9.33e-03	GO:0005576	extracellular region
2.58	1.80e-02	GO:0005925	focal adhesion
2.48	2.30e-02	GO:0030055	cell-substrate junction
2.46	3.84e-02	GO:0005924	cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.17	1.64e-02	GO:0005126	cytokine receptor binding
1.46	1.73e-02	GO:0005102	receptor binding