Motif ID: SNAI1..3.p2

Z-value: 6.890


Transcription factors associated with SNAI1..3.p2:

Gene SymbolEntrez IDGene Name
SNAI1 6615 snail homolog 1 (Drosophila)
SNAI2 6591 snail homolog 2 (Drosophila)
SNAI3 333929 snail homolog 3 (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SNAI3chr16_-_887528790.611.1e-01Click!
SNAI2chr8_-_498338230.502.1e-01Click!
SNAI1chr20_+_485995110.413.1e-01Click!


Activity profile for motif SNAI1..3.p2.

activity profile for motif SNAI1..3.p2


Sorted Z-values histogram for motif SNAI1..3.p2

Sorted Z-values for motif SNAI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SNAI1..3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_60280462 25.035 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr19_+_38755238 20.448 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755422 20.269 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr16_+_68679229 19.466 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr16_+_68771214 18.669 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr6_-_136871542 17.824 MAP7
microtubule-associated protein 7
chr19_+_38755097 17.672 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr14_-_61747956 17.664 TMEM30B
transmembrane protein 30B
chr19_+_35739282 16.981 LSR
lipolysis stimulated lipoprotein receptor
chr16_+_68771192 16.758 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr1_+_183155393 16.749 LAMC2
laminin, gamma 2
chr1_+_183155361 16.433 LAMC2
laminin, gamma 2
chr1_+_183155173 15.903 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr17_-_7165788 15.653 CLDN7
claudin 7
chr1_+_1981902 15.379 NM_002744
PRKCZ
protein kinase C, zeta
chr16_+_68679198 15.293 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr19_-_10697907 14.846 NM_005498
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr17_-_7166263 14.693 NM_001185023
NM_001307
CLDN7

claudin 7

chr14_-_61748510 14.529 NM_001017970
TMEM30B
transmembrane protein 30B
chr8_+_95653272 14.231 ESRP1
epithelial splicing regulatory protein 1
chr11_+_130029773 14.077 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr11_+_130029712 13.235 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr1_+_156030965 13.210 NM_020387
RAB25
RAB25, member RAS oncogene family
chr8_+_120220554 12.805 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr1_+_46646199 12.592 TSPAN1
tetraspanin 1
chr16_+_68771304 12.414 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr6_-_136871956 11.840 NM_001198616
NM_001198617
NM_003980
MAP7


microtubule-associated protein 7


chr5_+_68788387 11.837 NM_001205254
OCLN
occludin
chr19_+_35739519 11.813 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr19_+_6464259 11.626 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr18_+_21452981 11.550 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr8_+_102504836 11.382 GRHL2
grainyhead-like 2 (Drosophila)
chr19_+_35739778 11.251 LSR
lipolysis stimulated lipoprotein receptor
chr8_+_102504661 11.207 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr11_+_32851469 11.009 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr18_-_74844762 10.886 NM_001025100
NM_001025101
MBP

myelin basic protein

chr8_+_95653340 10.709 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr8_-_75233461 10.659 NM_020647
JPH1
junctophilin 1
chr1_-_160990862 10.568 F11R
F11 receptor
chr8_+_95653399 10.550 ESRP1
epithelial splicing regulatory protein 1
chr1_-_160990971 10.470 NM_016946
F11R
F11 receptor
chr4_+_155665150 10.191 NM_004744
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr1_-_27286875 9.982 NM_152365
C1orf172
chromosome 1 open reading frame 172
chr17_-_31203889 9.938 NM_015194
MYO1D
myosin ID
chr2_+_47596447 9.801 EPCAM
epithelial cell adhesion molecule
chr18_-_74844710 9.627 MBP
myelin basic protein
chr2_+_47596286 9.613 NM_002354
EPCAM
epithelial cell adhesion molecule
chr15_+_40545348 9.426 PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr17_+_73521744 9.400 NM_001015002
NM_001031803
NM_004524
LLGL2


lethal giant larvae homolog 2 (Drosophila)


chr1_+_200863948 9.372 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr17_-_39942937 9.319 NM_002230
NM_021991
JUP

junction plakoglobin

chr15_+_41136178 9.291 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr11_+_130029663 9.152 NM_021978
ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr19_+_35607218 9.040 FXYD3
FXYD domain containing ion transport regulator 3
chr21_-_42219038 8.957 NM_001389
DSCAM
Down syndrome cell adhesion molecule
chr12_-_6484904 8.864 NM_001038
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr11_+_18287807 8.834 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr1_+_151483861 8.746 NM_020770
CGN
cingulin
chr2_+_223289285 8.684 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr15_+_41136622 8.618 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr11_+_130029699 8.593 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr7_-_22396511 8.592 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr2_+_223289212 8.510 SGPP2
sphingosine-1-phosphate phosphatase 2
chr15_+_40531236 8.208 PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr11_+_394238 8.061 PKP3
plakophilin 3
chr22_+_40390935 8.030 NM_138435
FAM83F
family with sequence similarity 83, member F
chr1_-_201368716 7.881 LAD1
ladinin 1
chr18_-_47721165 7.813 NM_001080467
MYO5B
myosin VB
chr7_+_16793320 7.737 NM_014399
TSPAN13
tetraspanin 13
chr9_-_126030792 7.713 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr11_-_18270167 7.691 NM_001199744
NM_001127380
NM_030754
SAA2-SAA4
SAA2

SAA2-SAA4 readthrough
serum amyloid A2

chr9_+_35673852 7.521 NM_001216
CA9
carbonic anhydrase IX
chr16_-_68269948 7.474 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr7_-_98030165 7.382 BAIAP2L1
BAI1-associated protein 2-like 1
chr2_-_165477818 7.315 GRB14
growth factor receptor-bound protein 14
chr9_-_126030854 7.235 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr19_+_35739838 7.173 LSR
lipolysis stimulated lipoprotein receptor
chr20_+_49348050 7.100 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr17_+_9548853 7.074 NM_153210
USP43
ubiquitin specific peptidase 43
chr8_-_494834 7.068 C8orf42
chromosome 8 open reading frame 42
chr5_+_167718485 7.047 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr8_-_127570465 6.999 FAM84B
family with sequence similarity 84, member B
chr4_+_75310852 6.999 NM_001657
AREG
amphiregulin
chr18_+_29027731 6.957 NM_001944
DSG3
desmoglein 3
chr1_+_35247838 6.922 NM_001005752
GJB3
gap junction protein, beta 3, 31kDa
chr2_-_165477986 6.895 GRB14
growth factor receptor-bound protein 14
chr1_-_201368434 6.859 LAD1
ladinin 1
chr10_+_71390002 6.829 NM_145306
C10orf35
chromosome 10 open reading frame 35
chr1_-_209979388 6.821 NM_001206696
NM_006147
IRF6

interferon regulatory factor 6

chr12_+_56473808 6.801 NM_001982
NM_001005915
ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

chr1_-_201368617 6.727 NM_005558
LAD1
ladinin 1
chr11_-_11643542 6.664 NM_198516
GALNTL4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
chr7_-_98030426 6.632 NM_018842
BAIAP2L1
BAI1-associated protein 2-like 1
chr4_-_11430502 6.610 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr21_-_42218587 6.605 DSCAM
Down syndrome cell adhesion molecule
chr14_-_105635114 6.544 NM_002226
NM_145159
JAG2

jagged 2

chr4_+_85504056 6.474 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr13_-_20806533 6.454 NM_001110219
NM_001110220
NM_001110221
GJB6


gap junction protein, beta 6, 30kDa


chr3_-_48471401 6.439 NM_001130082
PLXNB1
plexin B1
chr3_-_111314181 6.369 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr11_+_10476665 6.345 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr4_-_36245893 6.319 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_+_37137882 6.240 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr5_+_166711842 6.226 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr1_+_3371020 6.171 NM_014448
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr1_+_95582827 6.160 NM_152487
TMEM56
transmembrane protein 56
chr8_+_86376130 6.157 NM_000067
CA2
carbonic anhydrase II
chr13_-_20767036 6.145 GJB2
gap junction protein, beta 2, 26kDa
chr6_+_36098261 6.137 NM_002754
MAPK13
mitogen-activated protein kinase 13
chrX_-_106449543 6.114 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chr15_+_40532034 6.103 NM_020168
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr2_-_216878314 6.102 NM_018000
MREG
melanoregulin
chr16_-_4987056 6.024 NM_002705
PPL
periplakin
chr19_-_51523272 5.987 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr17_-_39274587 5.954 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr3_-_69435223 5.883 FRMD4B
FERM domain containing 4B
chr6_+_150464156 5.864 NM_030949
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr6_+_30852756 5.802 NM_001202523
DDR1
discoidin domain receptor tyrosine kinase 1
chr8_+_82644663 5.775 NM_152284
CHMP4C
charged multivesicular body protein 4C
chr11_-_88070840 5.772 CTSC
cathepsin C
chrX_-_102565805 5.748 NM_001168399
NM_001168400
NM_001168401
NM_032621
BEX2



brain expressed X-linked 2



chr6_+_125475334 5.725 NM_001003395
TPD52L1
tumor protein D52-like 1
chr11_-_88070901 5.643 CTSC
cathepsin C
chr16_+_71660063 5.622 NM_001017967
NM_052858
MARVELD3

MARVEL domain containing 3

chr3_-_48470715 5.620 NM_002673
PLXNB1
plexin B1
chr1_+_62208091 5.597 NM_176877
INADL
InaD-like (Drosophila)
chr8_+_32405727 5.591 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr11_-_108464344 5.535 NM_015065
EXPH5
exophilin 5
chr17_-_31204071 5.477 MYO1D
myosin ID
chr8_-_144654921 5.459 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr2_+_17721806 5.441 NM_003385
VSNL1
visinin-like 1
chr11_+_45944155 5.434 GYLTL1B
glycosyltransferase-like 1B
chr10_-_135090325 5.374 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr17_-_7493389 5.338 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr20_-_6103562 5.314 FERMT1
fermitin family member 1
chr2_+_17721983 5.309 VSNL1
visinin-like 1
chr5_+_68788118 5.295 NM_002538
OCLN
occludin
chr15_+_90728118 5.275 NM_020210
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr3_+_189507448 5.235 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr21_+_18885296 5.209 CXADR
coxsackie virus and adenovirus receptor
chr15_-_44487237 5.198 NM_032892
FRMD5
FERM domain containing 5
chr9_-_131940481 5.159 IER5L
immediate early response 5-like
chr15_-_44487468 5.159 FRMD5
FERM domain containing 5
chr1_+_24645811 5.157 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr1_+_153003677 5.147 NM_003125
SPRR1B
small proline-rich protein 1B
chr1_-_85514174 5.080 NM_001253693
NM_018298
MCOLN3

mucolipin 3

chr11_+_394199 5.056 NM_007183
PKP3
plakophilin 3
chr1_+_2005424 5.026 NM_001242874
PRKCZ
protein kinase C, zeta
chr1_+_152956563 4.998 NM_001199828
NM_005987
SPRR1A

small proline-rich protein 1A

chr11_-_88070905 4.975 NM_001114173
NM_001814
NM_148170
CTSC


cathepsin C


chr11_-_118123001 4.944 NM_198275
MPZL3
myelin protein zero-like 3
chr1_-_85462622 4.922 NM_153259
MCOLN2
mucolipin 2
chr12_+_53342654 4.899 NM_199187
KRT18
keratin 18
chr12_-_6484389 4.846 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr12_-_53298765 4.835 NM_002273
KRT8
keratin 8
chr1_+_109792640 4.835 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr7_-_20256942 4.808 NM_182762
MACC1
metastasis associated in colon cancer 1
chr6_+_54711568 4.800 NM_001010872
FAM83B
family with sequence similarity 83, member B
chr7_+_148036528 4.781 CNTNAP2
contactin associated protein-like 2
chr2_+_163200582 4.730 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chr2_-_208634051 4.728 NM_003468
FZD5
frizzled family receptor 5
chr19_+_7660698 4.690 NM_001080429
NM_020902
CAMSAP3

calmodulin regulated spectrin-associated protein family, member 3

chr1_+_234040547 4.669 NM_173508
SLC35F3
solute carrier family 35, member F3
chr3_+_50192420 4.645 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr7_-_143105897 4.642 NM_005232
EPHA1
EPH receptor A1
chr5_+_68710938 4.641 NM_001038603
NM_001244734
MARVELD2

MARVEL domain containing 2

chr13_-_20767100 4.619 NM_004004
GJB2
gap junction protein, beta 2, 26kDa
chr11_+_1860232 4.608 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr19_+_45843997 4.601 NM_177417
KLC3
kinesin light chain 3
chr16_+_30194925 4.580 CORO1A
coronin, actin binding protein, 1A
chr14_-_55369163 4.568 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr17_+_37894212 4.561 GRB7
growth factor receptor-bound protein 7
chr2_-_166650770 4.550 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr19_+_751108 4.529 NM_173481
C19orf21
chromosome 19 open reading frame 21
chr14_-_67878859 4.503 PLEK2
pleckstrin 2
chr8_-_144815888 4.478 NM_198488
FAM83H
family with sequence similarity 83, member H
chr16_+_30194730 4.446 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr11_+_68079999 4.440 NM_002335
LRP5
low density lipoprotein receptor-related protein 5
chr14_-_67878770 4.422 NM_016445
PLEK2
pleckstrin 2
chr9_+_93564073 4.417 SYK
spleen tyrosine kinase
chr9_+_93564063 4.391 SYK
spleen tyrosine kinase
chr4_+_75480628 4.387 NM_001657
AREG
amphiregulin
chr4_-_10023094 4.385 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr19_+_45281125 4.381 NM_001130852
NM_012116
CBLC

Cas-Br-M (murine) ecotropic retroviral transforming sequence c

chrX_+_37545008 4.379 NM_021083
XK
X-linked Kx blood group (McLeod syndrome)
chr10_+_71211215 4.370 NM_012339
TSPAN15
tetraspanin 15
chr17_+_7942351 4.345 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr11_-_17035948 4.338 NM_175058
PLEKHA7
pleckstrin homology domain containing, family A member 7
chr1_-_12677347 4.277 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr17_+_39382878 4.265 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr12_+_56473944 4.264 ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr5_-_60140041 4.250 NM_001104558
NM_024930
ELOVL7

ELOVL fatty acid elongase 7

chr16_-_75529289 4.222


chr11_-_119234628 4.221 USP2
ubiquitin specific peptidase 2
chr12_+_53342842 4.197 NM_000224
KRT18
keratin 18
chr9_-_136024522 4.173 NM_001042368
RALGDS
ral guanine nucleotide dissociation stimulator
chr9_+_93564099 4.162 SYK
spleen tyrosine kinase
chr12_-_48298765 4.129 NM_000376
NM_001017535
NM_001017536
VDR


vitamin D (1,25- dihydroxyvitamin D3) receptor


chr4_-_25864430 4.119 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr6_+_143382030 4.061 AIG1
androgen-induced 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 5.95e-11 GO:0009987 cellular process
1.17 7.57e-07 GO:0023052 signaling
1.17 1.08e-05 GO:0007165 signal transduction
1.13 3.74e-04 GO:0051716 cellular response to stimulus
1.20 4.76e-03 GO:0007166 cell surface receptor linked signaling pathway
1.07 9.79e-03 GO:0065007 biological regulation
1.24 1.06e-02 GO:0002376 immune system process
1.70 1.10e-02 GO:0034330 cell junction organization
1.27 1.72e-02 GO:0006811 ion transport
1.14 1.91e-02 GO:0048856 anatomical structure development
1.13 2.55e-02 GO:0007275 multicellular organismal development
1.12 3.81e-02 GO:0051179 localization
1.14 4.11e-02 GO:0048731 system development
1.27 4.15e-02 GO:0055085 transmembrane transport
1.27 4.62e-02 GO:0044093 positive regulation of molecular function

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.25 1.10e-09 GO:0044459 plasma membrane part
1.09 1.16e-06 GO:0016020 membrane
1.10 2.15e-05 GO:0044425 membrane part
1.37 2.00e-04 GO:0030054 cell junction
1.25 2.39e-04 GO:0005887 integral to plasma membrane
1.24 5.19e-04 GO:0031226 intrinsic to plasma membrane
1.28 1.75e-03 GO:0005626 insoluble fraction
1.54 1.79e-03 GO:0016323 basolateral plasma membrane
1.28 2.29e-03 GO:0005624 membrane fraction
1.11 7.26e-03 GO:0071944 cell periphery
1.11 7.26e-03 GO:0005886 plasma membrane
1.09 7.95e-03 GO:0016021 integral to membrane
1.09 9.36e-03 GO:0031224 intrinsic to membrane
1.38 1.35e-02 GO:0009986 cell surface
1.18 1.52e-02 GO:0012505 endomembrane system
1.57 1.57e-02 GO:0070161 anchoring junction
1.06 1.87e-02 GO:0005737 cytoplasm
1.50 3.08e-02 GO:0005911 cell-cell junction
1.20 4.40e-02 GO:0000267 cell fraction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.09 7.19e-05 GO:0005515 protein binding
1.94 1.82e-03 GO:0015294 solute:cation symporter activity
1.18 2.48e-03 GO:0032553 ribonucleotide binding
1.18 2.48e-03 GO:0032555 purine ribonucleotide binding
1.18 3.06e-03 GO:0017076 purine nucleotide binding
1.33 8.50e-03 GO:0008324 cation transmembrane transporter activity
1.17 9.03e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.28 1.32e-02 GO:0015075 ion transmembrane transporter activity
1.67 1.93e-02 GO:0015293 symporter activity
1.18 2.88e-02 GO:0032559 adenyl ribonucleotide binding
1.18 3.06e-02 GO:0030554 adenyl nucleotide binding