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Motif ID: SOX5.p2

Z-value: 0.644

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_-_92413738	1.770		FBLN5	fibulin 5
chr14_-_92414004	1.392	NM_006329	FBLN5	fibulin 5
chr1_+_163038564	1.140	NM_005613	RGS4	regulator of G-protein signaling 4
chr2_+_189839132	0.799		COL3A1	collagen, type III, alpha 1
chr8_-_108510094	0.760	NM_001146 NM_001199859	ANGPT1	angiopoietin 1
chr3_-_114790221	0.674	NM_001164343	ZBTB20	zinc finger and BTB domain containing 20
chr6_-_46293404	0.600		RCAN2	regulator of calcineurin 2
chr5_-_111312522	0.541	NM_001142474 NM_001142475	C5orf13	chromosome 5 open reading frame 13
chr1_+_163038934	0.527	NM_001113381	RGS4	regulator of G-protein signaling 4
chr5_-_147286064	0.523	NM_206966	C5orf46	chromosome 5 open reading frame 46
chr9_-_95166827	0.515	NM_014057 NM_033014	OGN	osteoglycin
chr5_+_110407389	0.466	NM_033035	TSLP	thymic stromal lymphopoietin
chr8_-_93075190	0.431	NM_004349	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_67588395	0.407	NM_001242466	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_-_111092918	0.395	NM_004772	C5orf13	chromosome 5 open reading frame 13
chr5_-_158526698	0.383	NM_024007	EBF1	early B-cell factor 1
chr5_-_111093251	0.351	NM_001142479 NM_001142480 NM_001142478	C5orf13	chromosome 5 open reading frame 13
chr4_+_124317884	0.349	NM_199327	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr12_-_29937691	0.341	NM_175861	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr5_-_111093030	0.334	NM_001142482 NM_001142481	C5orf13	chromosome 5 open reading frame 13
chr2_-_163099877	0.331	NM_004460	FAP	fibroblast activation protein, alpha
chr3_-_151987332	0.327		LOC401093	uncharacterized LOC401093
chr1_-_232651227	0.325	NM_020808	SIPA1L2	signal-induced proliferation-associated 1 like 2
chrX_+_149613719	0.313	NM_001177466 NM_005491	MAMLD1	mastermind-like domain containing 1
chr5_-_111092865	0.313		C5orf13	chromosome 5 open reading frame 13
chr5_+_156820161	0.312		CYFIP2	cytoplasmic FMR1 interacting protein 2
chr4_-_159093523	0.311		FAM198B	family with sequence similarity 198, member B
chr12_-_91505215	0.310		LUM	lumican
chr17_-_19648924	0.307	NM_001135167	ALDH3A1	aldehyde dehydrogenase 3 family, member A1
chr3_+_154797644	0.305	NM_007287	MME	membrane metallo-endopeptidase
chr12_-_91505541	0.301	NM_002345	LUM	lumican
chr5_-_111091947	0.301	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr8_-_93115453	0.299	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr20_-_29993955	0.296	NM_001011878	DEFB121	defensin, beta 121
chr6_-_139695784	0.293	NM_006079	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr12_+_53443834	0.292	NM_170754	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr3_+_154797435	0.291	NM_000902	MME	membrane metallo-endopeptidase
chr8_-_38325241	0.291	NM_001174065 NM_001174066 NM_001174067	FGFR1	fibroblast growth factor receptor 1
chr17_+_65822206	0.280		BPTF	bromodomain PHD finger transcription factor
chr8_-_38326115	0.280		FGFR1	fibroblast growth factor receptor 1
chr8_-_38325524	0.278		FGFR1	fibroblast growth factor receptor 1
chr8_+_7693992	0.270	NM_080389 NM_001040702	DEFB104A DEFB104B	defensin, beta 104A defensin, beta 104B
chr4_-_2263808	0.267		MXD4	MAX dimerization protein 4
chr8_-_13134028	0.264		DLC1	deleted in liver cancer 1
chr6_-_139695739	0.263		CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr1_-_85930610	0.262		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr12_-_10605928	0.260	NM_002259 NM_007328	KLRC1	killer cell lectin-like receptor subfamily C, member 1
chr4_-_159093717	0.256	NM_016613	FAM198B	family with sequence similarity 198, member B
chr4_-_2263706	0.255	NM_006454	MXD4	MAX dimerization protein 4
chr6_-_139695349	0.251	NM_001168389 NM_001168388	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chrX_-_142723921	0.250	NM_001184749	SLITRK4	SLIT and NTRK-like family, member 4
chrX_-_135749436	0.248		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr9_-_97402530	0.246	NM_001127628	FBP1	fructose-1,6-bisphosphatase 1
chr8_-_93029864	0.244	NM_175636	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_+_118305427	0.230	NM_000936	PNLIP	pancreatic lipase
chr20_+_123230	0.229	NM_030931	DEFB126	defensin, beta 126
chr13_-_33760215	0.228	NM_001243466 NM_178007	STARD13	StAR-related lipid transfer (START) domain containing 13
chr7_-_47622127	0.226		TNS3	tensin 3
chr1_+_171060017	0.225	NM_001002294 NM_006894	FMO3	flavin containing monooxygenase 3
chr8_-_72274466	0.225	NM_000503	EYA1	eyes absent homolog 1 (Drosophila)
chr9_-_98268866	0.222		PTCH1	patched 1
chr22_+_38092994	0.220	NM_001039141	TRIOBP	TRIO and F-actin binding protein
chr9_+_118916069	0.220	NM_002581	PAPPA	pregnancy-associated plasma protein A, pappalysin 1
chr20_+_44462395	0.218	NM_001042632 NM_001042633 NM_033421 NM_152897	SNX21	sorting nexin family member 21
chr14_-_89883306	0.217	NM_005197	FOXN3	forkhead box N3
chr17_-_48264039	0.214		COL1A1	collagen, type I, alpha 1
chr3_-_18480203	0.213	NM_001131010	SATB1	SATB homeobox 1
chr1_-_86043932	0.213	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr17_+_65822242	0.212		BPTF	bromodomain PHD finger transcription factor
chr1_-_31345361	0.212		SDC3	syndecan 3
chr4_-_186732208	0.211	NM_001145671	SORBS2	sorbin and SH3 domain containing 2
chr15_+_76629101	0.209	NM_145805	ISL2	ISL LIM homeobox 2
chr8_+_105352050	0.207	NM_030788	TM7SF4	transmembrane 7 superfamily member 4
chr5_-_149535138	0.206		PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr10_-_32667543	0.206		EPC1	enhancer of polycomb homolog 1 (Drosophila)
chr9_+_18474078	0.205	NM_001040272 NM_052866	ADAMTSL1	ADAMTS-like 1
chr20_-_45985411	0.204	NM_012408 NM_183047 NM_183048	ZMYND8	zinc finger, MYND-type containing 8
chr6_-_152957985	0.202	NM_033071	SYNE1	spectrin repeat containing, nuclear envelope 1
chr2_-_200325200	0.201		SATB2	SATB homeobox 2
chrX_+_22050920	0.199	NM_000444	PHEX	phosphate regulating endopeptidase homolog, X-linked
chrX_+_54834107	0.198	NM_177433	MAGED2	melanoma antigen family D, 2
chr5_+_78407603	0.198	NM_001713	BHMT	betaine--homocysteine S-methyltransferase
chr13_+_93879011	0.196	NM_005708	GPC6	glypican 6
chr20_+_12989616	0.196	NM_018327	SPTLC3	serine palmitoyltransferase, long chain base subunit 3
chr2_-_225266710	0.195	NM_001122779 NM_024785	FAM124B	family with sequence similarity 124B
chr3_-_114343052	0.195	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr10_+_69869249	0.192	NM_032578	MYPN	myopalladin
chrX_-_106959597	0.188	NM_001015881	TSC22D3	TSC22 domain family, member 3
chr4_-_186732047	0.181	NM_001145672	SORBS2	sorbin and SH3 domain containing 2
chr11_+_19372270	0.179	NM_001111018	NAV2	neuron navigator 2
chr7_+_134576187	0.179		CALD1	caldesmon 1
chr1_+_198608244	0.178		PTPRC	protein tyrosine phosphatase, receptor type, C
chrX_-_100872926	0.176	NM_001009584 NM_001184768 NM_019007	ARMCX6	armadillo repeat containing, X-linked 6
chr14_-_52535711	0.175		NID2	nidogen 2 (osteonidogen)
chr10_+_63661012	0.174	NM_032199	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr11_+_46299554	0.173		CREB3L1	cAMP responsive element binding protein 3-like 1
chr17_+_67498391	0.172		MAP2K6	mitogen-activated protein kinase kinase 6
chr7_+_28448970	0.172		LOC401317	uncharacterized LOC401317
chr5_+_40841296	0.170	NM_032587	CARD6	caspase recruitment domain family, member 6
chr11_+_46299585	0.170		CREB3L1	cAMP responsive element binding protein 3-like 1
chr2_+_217498082	0.169	NM_000597	IGFBP2	insulin-like growth factor binding protein 2, 36kDa
chr1_+_201709051	0.169		NAV1	neuron navigator 1
chr1_+_145524989	0.169	NM_003637	ITGA10	integrin, alpha 10
chr1_+_50571963	0.168	NM_001144775	ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr7_-_19157262	0.167	NM_000474	TWIST1	twist homolog 1 (Drosophila)
chr6_+_89790464	0.166		PNRC1	proline-rich nuclear receptor coactivator 1
chr8_-_72273965	0.165		EYA1	eyes absent homolog 1 (Drosophila)
chr6_+_89790412	0.165	NM_006813	PNRC1	proline-rich nuclear receptor coactivator 1
chr16_+_55515468	0.165	NM_001127891	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr7_-_47621635	0.163		TNS3	tensin 3
chr1_-_193155723	0.161	NM_003783	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr14_-_52535765	0.160		NID2	nidogen 2 (osteonidogen)
chr11_-_102401430	0.159	NM_002423	MMP7	matrix metallopeptidase 7 (matrilysin, uterine)
chr16_+_86612114	0.159	NM_005250	FOXL1	forkhead box L1
chr6_+_119215240	0.156	NM_014034	ASF1A	ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr3_-_165555167	0.156		BCHE	butyrylcholinesterase
chr1_-_156217717	0.155	NM_198406 NM_024897	PAQR6	progestin and adipoQ receptor family member VI
chr21_-_28339405	0.155	NM_007038	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr18_+_72922725	0.154	NM_005786	TSHZ1	teashirt zinc finger homeobox 1
chr3_+_12330336	0.154	NM_138711	PPARG	peroxisome proliferator-activated receptor gamma
chr6_+_155538096	0.154	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chr13_-_74708361	0.153		KLF12	Kruppel-like factor 12
chr1_+_221052735	0.152	NM_021958	HLX	H2.0-like homeobox
chr7_-_27142301	0.151	NM_006735	HOXA2	homeobox A2
chr3_-_122283423	0.151	NM_001146103 NM_031458	PARP9	poly (ADP-ribose) polymerase family, member 9
chr11_+_65192284	0.150		NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr5_+_156696351	0.149	NM_014376	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr1_-_108231122	0.149	NM_001079874	VAV3	vav 3 guanine nucleotide exchange factor
chr10_+_31610063	0.147	NM_001128128 NM_001174094	ZEB1	zinc finger E-box binding homeobox 1
chr6_+_132891460	0.147	NM_175067	TAAR6	trace amine associated receptor 6
chr4_-_175443601	0.146		HPGD	hydroxyprostaglandin dehydrogenase 15-(NAD)
chr5_-_168271852	0.146
chr7_+_104681378	0.146		MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr3_+_12392993	0.146	NM_015869	PPARG	peroxisome proliferator-activated receptor gamma
chr18_-_52625278	0.146	NM_001143829	CCDC68	coiled-coil domain containing 68
chrX_-_154250769	0.145	NM_000132	F8	coagulation factor VIII, procoagulant component
chr7_-_47621741	0.145	NM_022748	TNS3	tensin 3
chr1_+_174844655	0.144	NM_001035230	RABGAP1L	RAB GTPase activating protein 1-like
chr10_+_99079017	0.143	NM_005479	FRAT1	frequently rearranged in advanced T-cell lymphomas
chr4_-_104020964	0.143	NM_020139	BDH2	3-hydroxybutyrate dehydrogenase, type 2
chr1_+_164528914	0.143		PBX1	pre-B-cell leukemia homeobox 1
chr2_+_109237679	0.140	NM_001193484	LIMS1	LIM and senescent cell antigen-like domains 1
chr5_-_171710794	0.140	NM_152277	UBTD2	ubiquitin domain containing 2
chr14_-_73493744	0.139	NM_021260	ZFYVE1	zinc finger, FYVE domain containing 1
chr17_+_58677603	0.138		PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr14_-_52535737	0.138		NID2	nidogen 2 (osteonidogen)
chr4_+_113970784	0.137	NM_001148 NM_020977	ANK2	ankyrin 2, neuronal
chr8_-_57123827	0.137		PLAG1	pleiomorphic adenoma gene 1
chr22_-_19418998	0.136		HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr19_+_36132646	0.136	NM_014209	ETV2	ets variant 2
chr10_+_35416089	0.135		CREM	cAMP responsive element modulator
chr1_+_145663156	0.135		RNF115	ring finger protein 115
chr17_+_3100809	0.134	NM_012352	OR1A2	olfactory receptor, family 1, subfamily A, member 2
chrX_+_135251795	0.133	NM_001167819	FHL1	four and a half LIM domains 1
chr6_+_132129195	0.133		ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr3_+_69985750	0.133	NM_000248 NM_001184968 NM_198158 NM_198178	MITF	microphthalmia-associated transcription factor
chr14_+_53019865	0.132	NM_001099652	GPR137C	G protein-coupled receptor 137C
chr5_+_145718586	0.132	NM_002700	POU4F3	POU class 4 homeobox 3
chr1_+_51434447	0.132		CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr11_+_22696318	0.132	NM_005256	GAS2	growth arrest-specific 2
chrX_-_142722869	0.132	NM_173078	SLITRK4	SLIT and NTRK-like family, member 4
chr12_-_10607214	0.131	NM_213657 NM_213658	KLRC1	killer cell lectin-like receptor subfamily C, member 1
chr5_+_137203559	0.131		MYOT	myotilin
chr2_-_175869910	0.130	NM_001822 NM_001025201	CHN1	chimerin (chimaerin) 1
chr4_+_86699858	0.129		ARHGAP24	Rho GTPase activating protein 24
chr8_-_38325825	0.129		FGFR1	fibroblast growth factor receptor 1
chr1_+_114522029	0.129	NM_020190	OLFML3	olfactomedin-like 3
chr2_-_188312872	0.128	NM_005795	CALCRL	calcitonin receptor-like
chr16_-_67977956	0.128	NM_000229	LCAT	lecithin-cholesterol acyltransferase
chr12_-_31743822	0.128	NM_144973	DENND5B	DENN/MADD domain containing 5B
chr5_+_15500288	0.128	NM_012304	FBXL7	F-box and leucine-rich repeat protein 7
chr4_+_8951476	0.128	NM_001040071	LOC650293	seven transmembrane helix receptor
chr7_-_111846384	0.127	NM_014705	DOCK4	dedicator of cytokinesis 4
chr5_+_137203544	0.127	NM_001135940 NM_006790	MYOT	myotilin
chr1_-_182360400	0.126	NM_001033056	GLUL	glutamate-ammonia ligase
chr16_+_69726751	0.125		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr8_-_57123858	0.125	NM_001114634 NM_001114635 NM_002655	PLAG1	pleiomorphic adenoma gene 1
chr3_-_187871816	0.125		LPP-AS2	LPP antisense RNA 2 (non-protein coding)
chr5_-_154230157	0.124		C5orf4	chromosome 5 open reading frame 4
chr11_-_4599049	0.124	NM_144663	C11orf40	chromosome 11 open reading frame 40
chr4_+_86851425	0.124	NM_031305	ARHGAP24	Rho GTPase activating protein 24
chr4_+_55095433	0.124		PDGFRA	platelet-derived growth factor receptor, alpha polypeptide
chr13_-_33780142	0.123	NM_001243474 NM_052851	STARD13	StAR-related lipid transfer (START) domain containing 13
chr22_-_19419215	0.123	NM_003325	HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr4_+_160188997	0.123	NM_014247	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2
chr7_+_129932973	0.123	NM_001163446 NM_016352	CPA4	carboxypeptidase A4
chr22_-_19419177	0.122		HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr5_+_140782367	0.121	NM_018921 NM_032089	PCDHGA9	protocadherin gamma subfamily A, 9
chr16_+_69680959	0.119		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr3_-_66551341	0.119		LRIG1	leucine-rich repeats and immunoglobulin-like domains 1
chr2_-_128421965	0.119	NM_017980	LIMS2	LIM and senescent cell antigen-like domains 2
chr5_-_95158465	0.117	NM_001118890 NM_001243658 NM_001243659 NM_002064	GLRX	glutaredoxin (thioltransferase)
chr3_+_46616044	0.115	NM_001174136	TDGF1	teratocarcinoma-derived growth factor 1
chr5_-_38595506	0.115	NM_002310	LIFR	leukemia inhibitory factor receptor alpha
chrX_+_107683015	0.113	NM_000495 NM_033380	COL4A5	collagen, type IV, alpha 5
chr3_-_99594915	0.113	NM_014890	FILIP1L	filamin A interacting protein 1-like
chr3_-_48754589	0.112	NM_001005909 NM_001005910 NM_001005911 NM_001146178 NM_001146179 NM_001190316 NM_001190317 NM_016291	IP6K2	inositol hexakisphosphate kinase 2
chr1_+_33722158	0.112	NM_152493	ZNF362	zinc finger protein 362
chr1_-_163113129	0.111		RGS5	regulator of G-protein signaling 5
chr1_+_170633312	0.110	NM_006902 NM_022716	PRRX1	paired related homeobox 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.37	4.43e-04	GO:0048519	negative regulation of biological process
1.38	9.45e-04	GO:0048523	negative regulation of cellular process
1.14	2.67e-03	GO:0065007	biological regulation
1.73	4.11e-03	GO:0010629	negative regulation of gene expression
1.72	4.14e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.15	4.76e-03	GO:0050789	regulation of biological process
1.91	5.01e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.32	6.69e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.66	9.64e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.15	1.02e-02	GO:0050794	regulation of cellular process
1.24	1.10e-02	GO:0032502	developmental process
1.66	1.24e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
1.62	2.15e-02	GO:0009890	negative regulation of biosynthetic process
1.30	2.18e-02	GO:0010556	regulation of macromolecule biosynthetic process
1.71	2.34e-02	GO:0045892	negative regulation of transcription, DNA-dependent
1.24	3.16e-02	GO:0007275	multicellular organismal development
1.31	3.63e-02	GO:0006355	regulation of transcription, DNA-dependent
1.27	4.55e-02	GO:0031326	regulation of cellular biosynthetic process
1.68	4.59e-02	GO:0051253	negative regulation of RNA metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.16	9.22e-03	GO:0005634	nucleus
2.63	1.33e-02	GO:0005925	focal adhesion
2.53	1.69e-02	GO:0030055	cell-substrate junction
2.51	2.87e-02	GO:0005924	cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.13	1.21e-02	GO:0005515	protein binding
1.07	3.54e-02	GO:0005488	binding