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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: SP1.p2

Z-value: 1.092

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_-_66453561	1.302	NM_017983	WIPI1	WD repeat domain, phosphoinositide interacting 1
chr1_+_211432732	1.253		RCOR3	REST corepressor 3
chr20_+_62371218	1.210		SLC2A4RG	SLC2A4 regulator
chrX_-_1572648	1.132	NM_001173473	ASMTL	acetylserotonin O-methyltransferase-like
chr1_+_211432726	1.109		RCOR3	REST corepressor 3
chr10_+_135192694	1.087	NM_152911 NM_207127 NM_207128	PAOX	polyamine oxidase (exo-N4-amino)
chr17_+_79989485	1.086	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chrY_-_1522648	1.075	NM_001173473	ASMTL	acetylserotonin O-methyltransferase-like
chrX_-_134232663	1.068		LINC00087	long intergenic non-protein coding RNA 87
chr19_-_2015628	1.014	NM_017797	BTBD2	BTB (POZ) domain containing 2
chr9_+_130922471	0.961	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr17_-_43045612	0.954	NM_006688	C1QL1	complement component 1, q subcomponent-like 1
chr12_-_124457099	0.954	NM_025140	CCDC92	coiled-coil domain containing 92
chr21_+_47401644	0.941	NM_001848	COL6A1	collagen, type VI, alpha 1
chr17_+_55333843	0.878	NM_138962	MSI2	musashi homolog 2 (Drosophila)
chr10_+_134351272	0.862	NM_005539	INPP5A	inositol polyphosphate-5-phosphatase, 40kDa
chr10_-_15210610	0.842	NM_004808	NMT2	N-myristoyltransferase 2
chr16_+_1203240	0.839	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr20_+_62371109	0.820	NM_020062	SLC2A4RG	SLC2A4 regulator
chrX_+_134555867	0.814		LINC00086	long intergenic non-protein coding RNA 86
chr6_-_33285493	0.814	NM_005453	ZBTB22	zinc finger and BTB domain containing 22
chr14_-_92413738	0.755		FBLN5	fibulin 5
chr7_+_73498149	0.755		LIMK1	LIM domain kinase 1
chr6_-_31697568	0.744		DDAH2	dimethylarginine dimethylaminohydrolase 2
chr7_+_73498106	0.740	NM_002314	LIMK1	LIM domain kinase 1
chr3_-_52001388	0.739	NM_020418 NM_001174100 NM_033008	PCBP4	poly(rC) binding protein 4
chr5_+_139028025	0.736	NM_016463	CXXC5	CXXC finger protein 5
chr12_+_57482886	0.727		NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr2_+_30369868	0.723		YPEL5	yippee-like 5 (Drosophila)
chr2_-_100721128	0.718		AFF3	AF4/FMR2 family, member 3
chr2_-_145090028	0.702		GTDC1	glycosyltransferase-like domain containing 1
chr18_+_11981552	0.701		IMPA2	inositol(myo)-1(or 4)-monophosphatase 2
chr18_+_11981457	0.699		IMPA2	inositol(myo)-1(or 4)-monophosphatase 2
chr14_+_105941061	0.698	NM_001312	CRIP2	cysteine-rich protein 2
chr20_+_33464327	0.692	NM_001076552 NM_018677	ACSS2	acyl-CoA synthetase short-chain family member 2
chr2_+_24299751	0.689		LOC375190	UPF0638 protein B
chr5_+_130599745	0.683		CDC42SE2	CDC42 small effector 2
chr11_-_65686439	0.676	NM_001135635 NM_031450	C11orf68	chromosome 11 open reading frame 68
chr20_+_33464404	0.669		ACSS2	acyl-CoA synthetase short-chain family member 2
chr2_-_145090038	0.666	NM_001164629	GTDC1	glycosyltransferase-like domain containing 1
chr8_-_103251002	0.663	NM_001172477 NM_001172478 NM_015713	RRM2B	ribonucleotide reductase M2 B (TP53 inducible)
chr2_+_30369800	0.656		YPEL5	yippee-like 5 (Drosophila)
chr18_+_11981421	0.655	NM_014214	IMPA2	inositol(myo)-1(or 4)-monophosphatase 2
chr12_+_6875686	0.654		PTMS	parathymosin
chr6_-_33285718	0.653	NM_001145338	ZBTB22	zinc finger and BTB domain containing 22
chr12_+_56367832	0.653		RAB5B	RAB5B, member RAS oncogene family
chr2_+_24272583	0.638	NM_004116 NM_054033	FKBP1B	FK506 binding protein 1B, 12.6 kDa
chr6_-_30710219	0.634	NM_005803	FLOT1	flotillin 1
chr12_+_107349673	0.629		C12orf23	chromosome 12 open reading frame 23
chr2_+_30369749	0.626	NM_001127399 NM_001127400 NM_001127401 NM_016061	YPEL5	yippee-like 5 (Drosophila)
chr10_-_135171512	0.625	NM_001098483 NM_198472	C10orf125	chromosome 10 open reading frame 125
chr7_+_97910978	0.619	NM_001159491 NM_015379	BRI3	brain protein I3
chr6_-_31698033	0.613	NM_013974	DDAH2	dimethylarginine dimethylaminohydrolase 2
chr17_+_4613931	0.608		ARRB2	arrestin, beta 2
chr1_-_11751677	0.599	NM_001127325	MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)
chr16_-_8962842	0.598	NM_014316	CARHSP1	calcium regulated heat stable protein 1, 24kDa
chr10_-_81205091	0.596	NM_153367	ZCCHC24	zinc finger, CCHC domain containing 24
chr19_+_14544216	0.593		PKN1	protein kinase N1
chr8_-_38325524	0.590		FGFR1	fibroblast growth factor receptor 1
chr2_+_24272627	0.588		FKBP1B	FK506 binding protein 1B, 12.6 kDa
chr5_+_139028483	0.587		CXXC5	CXXC finger protein 5
chr11_-_575848	0.570		LOC143666	uncharacterized LOC143666
chr14_-_92414004	0.562	NM_006329	FBLN5	fibulin 5
chr17_-_76921453	0.562	NM_003255	TIMP2	TIMP metallopeptidase inhibitor 2
chr15_+_76135992	0.560		UBE2Q2	ubiquitin-conjugating enzyme E2Q family member 2
chr17_+_4613780	0.549	NM_004313 NM_199004	ARRB2	arrestin, beta 2
chr15_+_80445177	0.549	NM_000137	FAH	fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr2_-_127864505	0.549	NM_004305 NM_139343 NM_139344 NM_139345 NM_139346 NM_139347 NM_139348 NM_139349 NM_139350 NM_139351	BIN1	bridging integrator 1
chrX_-_1571733	0.548	NM_001173474 NM_004192	ASMTL	acetylserotonin O-methyltransferase-like
chrY_-_1521733	0.545	NM_001173474 NM_004192	ASMTL	acetylserotonin O-methyltransferase-like
chr16_+_77756388	0.537	NM_001105663 NM_001243657 NM_001243660 NM_001243661	NUDT7	nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr2_+_23608297	0.530	NM_052920	KLHL29	kelch-like 29 (Drosophila)
chr12_-_52845862	0.530	NM_005555	KRT6B	keratin 6B
chr18_+_61554938	0.524	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr12_+_132379262	0.522	NM_003565	ULK1	unc-51-like kinase 1 (C. elegans)
chr7_+_97911023	0.521		BRI3	brain protein I3
chr6_+_34205029	0.516		HMGA1	high mobility group AT-hook 1
chr19_-_40950238	0.512	NM_203344	SERTAD3	SERTA domain containing 3
chr1_-_236228382	0.510		NID1	nidogen 1
chr1_-_161102367	0.508		DEDD	death effector domain containing
chr11_-_66234176	0.508		MRPL11	mitochondrial ribosomal protein L11
chr6_-_31697953	0.507		DDAH2	dimethylarginine dimethylaminohydrolase 2
chr1_-_15850692	0.499		CASP9	caspase 9, apoptosis-related cysteine peptidase
chr1_+_159141376	0.498	NM_021189 NM_001127173	CADM3	cell adhesion molecule 3
chr14_+_105780903	0.495		PACS2	phosphofurin acidic cluster sorting protein 2
chr12_+_107349539	0.489	NM_152261	C12orf23	chromosome 12 open reading frame 23
chr19_-_51523272	0.488	NM_002776 NM_001077500	KLK10	kallikrein-related peptidase 10
chr1_+_155829259	0.484	NM_152280	SYT11	synaptotagmin XI
chr1_-_182360181	0.478		GLUL	glutamate-ammonia ligase
chr19_-_51522953	0.474	NM_145888	KLK10	kallikrein-related peptidase 10
chr19_-_49149252	0.473	NM_001217	CA11	carbonic anhydrase XI
chr1_-_236228374	0.472		NID1	nidogen 1
chr8_-_99837768	0.471	NM_006281	STK3	serine/threonine kinase 3
chr20_+_56884749	0.469	NM_020673	RAB22A	RAB22A, member RAS oncogene family
chr5_-_10761344	0.467	NM_004394	DAP	death-associated protein
chr19_-_47734215	0.467	NM_014417	BBC3	BCL2 binding component 3
chr2_-_43453146	0.467		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr1_-_161102210	0.466	NM_001039712	DEDD	death effector domain containing
chr6_-_167040700	0.466	NM_021135	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_+_56367696	0.461	NM_001252036 NM_001252037 NM_002868	RAB5B	RAB5B, member RAS oncogene family
chr7_+_8008416	0.461	NM_138426	GLCCI1	glucocorticoid induced transcript 1
chr19_+_14544100	0.461	NM_002741	PKN1	protein kinase N1
chr9_+_33817168	0.460	NM_017811	UBE2R2	ubiquitin-conjugating enzyme E2R 2
chr15_+_80445340	0.458		FAH	fumarylacetoacetate hydrolase (fumarylacetoacetase)
chrX_+_152760452	0.455		BGN	biglycan
chr12_+_56367876	0.450		RAB5B	RAB5B, member RAS oncogene family
chr7_-_130353579	0.450	NM_012133	COPG2	coatomer protein complex, subunit gamma 2
chr15_-_65579017	0.448	NM_017851	PARP16	poly (ADP-ribose) polymerase family, member 16
chr1_+_226250413	0.444		H3F3A	H3 histone, family 3A
chr9_-_86432546	0.443	NM_001135953 NM_025211	GKAP1	G kinase anchoring protein 1
chr14_+_105781180	0.443		PACS2	phosphofurin acidic cluster sorting protein 2
chrX_-_15872905	0.442
chr22_-_19165872	0.441		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr18_+_21452981	0.439	NM_000227 NM_001127718	LAMA3	laminin, alpha 3
chr1_-_38471170	0.437	NM_001243878 NM_004468	FHL3	four and a half LIM domains 3
chr17_-_76921076	0.435		TIMP2	TIMP metallopeptidase inhibitor 2
chr19_+_8478181	0.434	NM_001005415 NM_001005416 NM_016496	MARCH2	membrane-associated ring finger (C3HC4) 2
chrX_-_152736015	0.431		TREX2 HAUS7	three prime repair exonuclease 2 HAUS augmin-like complex, subunit 7
chr19_+_18208596	0.431	NM_015016	MAST3	microtubule associated serine/threonine kinase 3
chr4_-_2263706	0.427	NM_006454	MXD4	MAX dimerization protein 4
chr4_-_15939949	0.427		FGFBP1	fibroblast growth factor binding protein 1
chr20_-_61492945	0.425	NM_006602	TCFL5	transcription factor-like 5 (basic helix-loop-helix)
chr1_-_3528058	0.425	NM_001409	MEGF6	multiple EGF-like-domains 6
chr19_+_50879681	0.424	NM_007121	NR1H2	nuclear receptor subfamily 1, group H, member 2
chr5_-_111093251	0.424	NM_001142479 NM_001142480 NM_001142478	C5orf13	chromosome 5 open reading frame 13
chr5_-_10761179	0.424		DAP	death-associated protein
chr19_+_47778099	0.424	NM_178511	PRR24	proline rich 24
chr19_+_36359346	0.423	NM_001024807 NM_005166	APLP1	amyloid beta (A4) precursor-like protein 1
chr9_+_139972195	0.422		UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr6_+_108882104	0.421		FOXO3	forkhead box O3
chr3_+_184053682	0.420	NM_001171093	FAM131A	family with sequence similarity 131, member A
chr20_+_62371730	0.419		SLC2A4RG	SLC2A4 regulator
chr22_+_46546498	0.419	NM_001001928 NM_005036	PPARA	peroxisome proliferator-activated receptor alpha
chr7_+_100797685	0.419	NM_001283	AP1S1	adaptor-related protein complex 1, sigma 1 subunit
chr2_-_179315756	0.418	NM_003690	PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator
chr2_-_43453724	0.416		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr20_+_34742656	0.414	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr6_-_4135701	0.414	NM_001166010 NM_006117 NM_206836	ECI2	enoyl-CoA delta isomerase 2
chrX_-_101771641	0.413	NM_021992	TMSB15A TMSB15B	thymosin beta 15a thymosin beta 15B
chr15_+_63481713	0.413	NM_016530	RAB8B	RAB8B, member RAS oncogene family
chr2_+_10443020	0.412	NM_002149	HPCAL1	hippocalcin-like 1
chr11_-_67120943	0.411	NM_021173	POLD4	polymerase (DNA-directed), delta 4
chr19_-_3028901	0.411	NM_003260	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr22_-_41985810	0.410	NM_002676	PMM1	phosphomannomutase 1
chr6_-_167040506	0.406		RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr15_+_72410724	0.405		SENP8	SUMO/sentrin specific peptidase family member 8
chr17_+_81037504	0.403	NM_001004431	METRNL	meteorin, glial cell differentiation regulator-like
chr17_-_7307413	0.403	NM_152766	C17orf61-PLSCR3 C17orf61	C17orf61-PLSCR3 readthrough chromosome 17 open reading frame 61
chr11_-_64570621	0.403	NM_004579	MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2
chr20_+_62371619	0.402		SLC2A4RG	SLC2A4 regulator
chr20_-_3154169	0.402		ProSAPiP1	ProSAPiP1 protein
chr9_+_132934685	0.402	NM_014286	NCS1	neuronal calcium sensor 1
chr1_-_19811951	0.400		CAPZB	capping protein (actin filament) muscle Z-line, beta
chr1_-_43283044	0.400	NM_199342	CCDC23	coiled-coil domain containing 23
chr11_+_65292576	0.400		SCYL1	SCY1-like 1 (S. cerevisiae)
chr5_+_148520985	0.399	NM_014945	ABLIM3	actin binding LIM protein family, member 3
chr21_-_38639593	0.399		DSCR3	Down syndrome critical region gene 3
chr9_+_124030455	0.399		GSN	gelsolin
chr1_-_173446273	0.398		LOC100506023	uncharacterized LOC100506023
chr1_-_12677347	0.397	NM_004753	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr7_-_28220146	0.396		JAZF1	JAZF zinc finger 1
chr1_-_236228476	0.395	NM_002508	NID1	nidogen 1
chr1_-_15850776	0.395	NM_001229 NM_032996	CASP9	caspase 9, apoptosis-related cysteine peptidase
chr11_+_64001974	0.395	NM_001243733 NM_003377	VEGFB	vascular endothelial growth factor B
chr16_+_29817810	0.394	NM_001042539 NM_002383	MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr8_+_144816287	0.393		LOC100128338	uncharacterized LOC100128338
chr9_+_139743852	0.393		PHPT1	phosphohistidine phosphatase 1
chr4_+_129732427	0.392		PHF17	PHD finger protein 17
chr6_+_37787592	0.392		ZFAND3	zinc finger, AN1-type domain 3
chr13_+_114239587	0.392		TFDP1	transcription factor Dp-1
chr20_+_32581725	0.391		RALY	RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr12_-_8815266	0.390		MFAP5	microfibrillar associated protein 5
chr6_-_111136330	0.388		CDK19	cyclin-dependent kinase 19
chr9_+_133320093	0.388	NM_000050 NM_054012	ASS1	argininosuccinate synthase 1
chr10_-_21463019	0.387	NM_001173484 NM_213569	NEBL	nebulette
chr10_+_131265453	0.386	NM_002412	MGMT	O-6-methylguanine-DNA methyltransferase
chr7_+_90225607	0.386		CDK14	cyclin-dependent kinase 14
chr10_+_131265500	0.384		MGMT	O-6-methylguanine-DNA methyltransferase
chr17_-_76921205	0.383		TIMP2	TIMP metallopeptidase inhibitor 2
chr19_+_33166312	0.382	NM_207391	RGS9BP	regulator of G protein signaling 9 binding protein
chr7_+_73703704	0.382	NM_003388 NM_032421	CLIP2	CAP-GLY domain containing linker protein 2
chr12_+_111843743	0.381	NM_005475	SH2B3	SH2B adaptor protein 3
chr14_-_89883306	0.380	NM_005197	FOXN3	forkhead box N3
chr22_-_19166296	0.380	NM_005984	SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr17_+_17206626	0.379	NM_020201	NT5M	5',3'-nucleotidase, mitochondrial
chr10_+_11784355	0.378	NM_024693	ECHDC3	enoyl CoA hydratase domain containing 3
chr9_+_124030413	0.378		GSN	gelsolin
chr3_+_12329332	0.378	NM_005037 NM_138712	PPARG	peroxisome proliferator-activated receptor gamma
chr19_+_3094528	0.378		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr8_-_74659082	0.377	NM_001164380 NM_001164381 NM_001164382 NM_001164383 NM_001164385 NM_014393	STAU2	staufen, RNA binding protein, homolog 2 (Drosophila)
chr5_-_9546157	0.373	NM_003966	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr7_+_73498318	0.373		LIMK1	LIM domain kinase 1
chr22_+_18893735	0.373	NM_005675	DGCR6	DiGeorge syndrome critical region gene 6
chr14_-_99947113	0.373		SETD3	SET domain containing 3
chr19_-_16582810	0.372		EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1
chr5_-_150537261	0.371		ANXA6	annexin A6
chrX_+_153665258	0.371	NM_001493	GDI1	GDP dissociation inhibitor 1
chr14_+_96505566	0.369	NM_001252507	C14orf132	chromosome 14 open reading frame 132
chr21_-_47648685	0.369		LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr20_+_34894190	0.369		DLGAP4	discs, large (Drosophila) homolog-associated protein 4

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.08	1.80e-26	GO:0009987	cellular process
1.13	5.08e-23	GO:0044237	cellular metabolic process
1.16	8.80e-20	GO:0044260	cellular macromolecule metabolic process
1.11	1.03e-18	GO:0008152	metabolic process
1.19	1.20e-16	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18	1.53e-16	GO:0034641	cellular nitrogen compound metabolic process
1.11	9.26e-16	GO:0044238	primary metabolic process
1.09	9.52e-16	GO:0065007	biological regulation
1.17	1.30e-15	GO:0006807	nitrogen compound metabolic process
1.10	6.32e-15	GO:0050789	regulation of biological process
1.10	8.37e-15	GO:0050794	regulation of cellular process
1.13	9.49e-15	GO:0043170	macromolecule metabolic process
1.14	3.75e-11	GO:0080090	regulation of primary metabolic process
1.14	4.93e-11	GO:0031323	regulation of cellular metabolic process
1.13	2.30e-10	GO:0019222	regulation of metabolic process
1.18	5.17e-10	GO:0090304	nucleic acid metabolic process
1.13	3.52e-09	GO:0060255	regulation of macromolecule metabolic process
1.18	1.66e-08	GO:0006464	protein modification process
1.12	5.34e-08	GO:0071840	cellular component organization or biogenesis
1.14	9.57e-08	GO:0051171	regulation of nitrogen compound metabolic process
1.12	9.78e-08	GO:0016043	cellular component organization
1.17	1.49e-07	GO:0043412	macromolecule modification
1.14	1.82e-07	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14	5.77e-07	GO:0044267	cellular protein metabolic process
1.14	1.30e-06	GO:0048522	positive regulation of cellular process
1.19	1.88e-06	GO:0035556	intracellular signal transduction
1.13	2.12e-06	GO:0071841	cellular component organization or biogenesis at cellular level
1.14	2.28e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.21	2.60e-06	GO:0044248	cellular catabolic process
1.13	3.61e-06	GO:0010468	regulation of gene expression
1.13	3.79e-06	GO:0071842	cellular component organization at cellular level
1.17	1.14e-05	GO:0006996	organelle organization
1.13	1.23e-05	GO:0031326	regulation of cellular biosynthetic process
1.24	1.58e-05	GO:0033554	cellular response to stress
1.12	2.50e-05	GO:0048518	positive regulation of biological process
1.27	3.21e-05	GO:0010629	negative regulation of gene expression
1.27	3.97e-05	GO:0006259	DNA metabolic process
1.12	4.31e-05	GO:0009889	regulation of biosynthetic process
1.13	4.37e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.13	4.64e-05	GO:0048519	negative regulation of biological process
1.24	5.87e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14	6.71e-05	GO:0048523	negative regulation of cellular process
1.22	6.84e-05	GO:0010605	negative regulation of macromolecule metabolic process
1.21	9.02e-05	GO:0009892	negative regulation of metabolic process
1.13	9.20e-05	GO:0051252	regulation of RNA metabolic process
1.25	1.05e-04	GO:0051254	positive regulation of RNA metabolic process
1.23	1.15e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
1.26	1.20e-04	GO:0045893	positive regulation of transcription, DNA-dependent
1.32	1.45e-04	GO:0007264	small GTPase mediated signal transduction
1.28	1.61e-04	GO:0006753	nucleoside phosphate metabolic process
1.28	1.61e-04	GO:0009117	nucleotide metabolic process
1.28	1.71e-04	GO:0006974	response to DNA damage stimulus
1.16	1.83e-04	GO:0009056	catabolic process
1.25	1.95e-04	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.33	1.98e-04	GO:0016568	chromatin modification
1.21	2.02e-04	GO:0008219	cell death
1.09	2.02e-04	GO:0051716	cellular response to stimulus
1.18	2.06e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.41	2.96e-04	GO:0048011	nerve growth factor receptor signaling pathway
1.23	3.41e-04	GO:0009890	negative regulation of biosynthetic process
1.16	3.42e-04	GO:0007399	nervous system development
1.18	3.67e-04	GO:0031325	positive regulation of cellular metabolic process
1.12	3.70e-04	GO:0044249	cellular biosynthetic process
1.15	4.12e-04	GO:0009059	macromolecule biosynthetic process
1.21	4.47e-04	GO:0016265	death
1.15	4.57e-04	GO:0034645	cellular macromolecule biosynthetic process
1.24	5.19e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.22	5.26e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
1.33	5.28e-04	GO:0006281	DNA repair
1.23	6.58e-04	GO:0010628	positive regulation of gene expression
1.23	6.59e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.26	7.08e-04	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.14	7.77e-04	GO:0016070	RNA metabolic process
1.26	8.39e-04	GO:0045892	negative regulation of transcription, DNA-dependent
1.21	1.05e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.19	1.08e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.18	1.12e-03	GO:0007049	cell cycle
1.17	1.24e-03	GO:0009893	positive regulation of metabolic process
1.11	1.39e-03	GO:0009058	biosynthetic process
1.25	1.40e-03	GO:0051253	negative regulation of RNA metabolic process
1.38	1.56e-03	GO:0051129	negative regulation of cellular component organization
1.23	1.95e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.12	2.00e-03	GO:0006355	regulation of transcription, DNA-dependent
1.13	2.19e-03	GO:0010467	gene expression
1.23	2.42e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14	2.68e-03	GO:0023051	regulation of signaling
1.19	2.82e-03	GO:0031324	negative regulation of cellular metabolic process
1.10	3.23e-03	GO:0019538	protein metabolic process
1.15	3.32e-03	GO:0009966	regulation of signal transduction
1.25	3.51e-03	GO:0044265	cellular macromolecule catabolic process
1.19	3.88e-03	GO:0009891	positive regulation of biosynthetic process
1.35	3.90e-03	GO:0009166	nucleotide catabolic process
1.21	4.20e-03	GO:0012501	programmed cell death
1.19	4.36e-03	GO:0006351	transcription, DNA-dependent
1.17	6.37e-03	GO:0032268	regulation of cellular protein metabolic process
1.22	7.14e-03	GO:0051276	chromosome organization
1.35	7.66e-03	GO:0006195	purine nucleotide catabolic process
1.34	8.53e-03	GO:0072523	purine-containing compound catabolic process
1.42	8.62e-03	GO:0051493	regulation of cytoskeleton organization
1.26	8.93e-03	GO:0072521	purine-containing compound metabolic process
1.20	9.41e-03	GO:0006915	apoptosis
1.22	1.08e-02	GO:0009057	macromolecule catabolic process
1.25	1.28e-02	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.21	1.29e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.48	1.74e-02	GO:0043254	regulation of protein complex assembly
1.19	1.84e-02	GO:0016192	vesicle-mediated transport
1.21	1.98e-02	GO:0051726	regulation of cell cycle
1.24	2.03e-02	GO:0006325	chromatin organization
1.72	2.10e-02	GO:0051403	stress-activated MAPK cascade
1.16	2.41e-02	GO:0051246	regulation of protein metabolic process
1.17	2.63e-02	GO:0022008	neurogenesis
1.34	2.90e-02	GO:0009143	nucleoside triphosphate catabolic process
1.34	2.90e-02	GO:0009154	purine ribonucleotide catabolic process
1.34	3.00e-02	GO:0009261	ribonucleotide catabolic process
1.31	3.15e-02	GO:0034655	nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.31	3.15e-02	GO:0034656	nucleobase, nucleoside and nucleotide catabolic process
1.23	3.25e-02	GO:0007010	cytoskeleton organization
1.22	3.25e-02	GO:0044282	small molecule catabolic process
1.23	3.27e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.18	3.65e-02	GO:0051128	regulation of cellular component organization
1.62	3.72e-02	GO:0034138	toll-like receptor 3 signaling pathway
1.34	3.80e-02	GO:0009146	purine nucleoside triphosphate catabolic process
1.41	3.93e-02	GO:0046039	GTP metabolic process
1.22	4.01e-02	GO:0016071	mRNA metabolic process
1.42	4.33e-02	GO:0006184	GTP catabolic process
1.26	4.42e-02	GO:0006163	purine nucleotide metabolic process
1.11	4.72e-02	GO:0048869	cellular developmental process
1.18	4.85e-02	GO:0046907	intracellular transport
1.63	4.90e-02	GO:0051494	negative regulation of cytoskeleton organization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.12	2.26e-79	GO:0005622	intracellular
1.12	2.63e-78	GO:0044424	intracellular part
1.12	1.63e-49	GO:0043226	organelle
1.12	3.98e-49	GO:0043229	intracellular organelle
1.13	1.68e-48	GO:0043227	membrane-bounded organelle
1.13	1.06e-47	GO:0043231	intracellular membrane-bounded organelle
1.13	3.64e-43	GO:0005737	cytoplasm
1.17	4.07e-38	GO:0005634	nucleus
1.26	1.20e-24	GO:0044428	nuclear part
1.27	1.86e-23	GO:0031981	nuclear lumen
1.24	2.30e-22	GO:0070013	intracellular organelle lumen
1.23	3.80e-21	GO:0043233	organelle lumen
1.23	4.40e-21	GO:0031974	membrane-enclosed lumen
1.12	5.37e-21	GO:0044444	cytoplasmic part
1.13	2.16e-20	GO:0044446	intracellular organelle part
1.13	8.23e-20	GO:0044422	organelle part
1.23	3.23e-18	GO:0005829	cytosol
1.27	5.94e-16	GO:0005654	nucleoplasm
1.03	1.99e-10	GO:0044464	cell part
1.03	2.30e-10	GO:0005623	cell
1.14	2.60e-09	GO:0043228	non-membrane-bounded organelle
1.14	2.60e-09	GO:0043232	intracellular non-membrane-bounded organelle
1.11	8.08e-06	GO:0043234	protein complex
1.24	2.03e-05	GO:0015630	microtubule cytoskeleton
1.26	2.48e-04	GO:0005730	nucleolus
1.24	2.74e-04	GO:0005694	chromosome
1.09	3.83e-04	GO:0032991	macromolecular complex
1.21	3.96e-04	GO:0044451	nucleoplasm part
1.13	4.88e-03	GO:0005856	cytoskeleton
1.15	1.53e-02	GO:0005794	Golgi apparatus
1.34	2.40e-02	GO:0005819	spindle
1.25	3.12e-02	GO:0005815	microtubule organizing center
1.54	4.50e-02	GO:0034399	nuclear periphery

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.08	1.06e-36	GO:0005488	binding
1.14	2.41e-35	GO:0005515	protein binding
1.19	7.04e-14	GO:0000166	nucleotide binding
1.15	1.62e-12	GO:0003676	nucleic acid binding
1.10	2.49e-10	GO:0003824	catalytic activity
1.18	2.12e-09	GO:0035639	purine ribonucleoside triphosphate binding
1.18	3.14e-09	GO:0032553	ribonucleotide binding
1.18	3.14e-09	GO:0032555	purine ribonucleotide binding
1.17	6.04e-09	GO:0017076	purine nucleotide binding
1.17	3.36e-07	GO:0016740	transferase activity
1.25	1.80e-06	GO:0019899	enzyme binding
1.13	5.38e-06	GO:0003677	DNA binding
1.15	8.28e-05	GO:0032559	adenyl ribonucleotide binding
1.20	9.33e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.15	9.36e-05	GO:0005524	ATP binding
1.15	1.07e-04	GO:0030554	adenyl nucleotide binding
1.21	2.19e-04	GO:0016301	kinase activity
1.30	3.14e-04	GO:0005525	GTP binding
1.18	3.27e-04	GO:0001071	nucleic acid binding transcription factor activity
1.18	3.27e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.25	4.40e-04	GO:0008092	cytoskeletal protein binding
1.20	5.34e-04	GO:0003723	RNA binding
1.17	1.40e-03	GO:0030528	transcription regulator activity
1.20	2.10e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.28	2.31e-03	GO:0019001	guanyl nucleotide binding
1.28	2.31e-03	GO:0032561	guanyl ribonucleotide binding
1.25	3.13e-03	GO:0030695	GTPase regulator activity
1.36	4.17e-03	GO:0003924	GTPase activity
1.40	7.92e-03	GO:0005085	guanyl-nucleotide exchange factor activity
1.28	8.34e-03	GO:0003779	actin binding
1.24	9.49e-03	GO:0004674	protein serine/threonine kinase activity
1.22	1.87e-02	GO:0060589	nucleoside-triphosphatase regulator activity
1.18	4.47e-02	GO:0043565	sequence-specific DNA binding
1.51	4.92e-02	GO:0008135	translation factor activity, nucleic acid binding