Motif ID: SPZ1.p2

Z-value: 0.852


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPZ1chr5_+_79615789-0.147.5e-01Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_72596699 0.399 RIMS1
regulating synaptic membrane exocytosis 1
chr9_+_12775713 0.377 C9orf150
chromosome 9 open reading frame 150
chr19_+_17581276 0.328 NM_198580
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr1_-_935352 0.300 HES4
hairy and enhancer of split 4 (Drosophila)
chr1_+_27668499 0.291 SYTL1
synaptotagmin-like 1
chr19_+_35739838 0.289 LSR
lipolysis stimulated lipoprotein receptor
chr19_-_6720585 0.284 NM_000064
C3
complement component 3
chr1_-_32801606 0.254 NM_023009
MARCKSL1
MARCKS-like 1
chr1_-_184006491 0.234 GLT25D2
glycosyltransferase 25 domain containing 2
chr3_-_18466759 0.230 NM_001195470
NM_002971
SATB1

SATB homeobox 1

chr10_+_111969988 0.224 NM_001008541
MXI1
MAX interactor 1
chr2_+_46524448 0.223 NM_001430
EPAS1
endothelial PAS domain protein 1
chr6_+_72596648 0.213 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr11_-_120008219 0.209 TRIM29
tripartite motif containing 29
chr19_+_35739519 0.207 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr17_-_42200957 0.205 HDAC5
histone deacetylase 5
chr16_+_29912146 0.204 NM_181718
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr6_+_72596405 0.198 RIMS1
regulating synaptic membrane exocytosis 1
chr7_+_94285620 0.196 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr8_+_104512975 0.194 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr16_+_85645014 0.194 NM_001134473
KIAA0182
KIAA0182
chr15_+_60296506 0.193 FOXB1
forkhead box B1
chr11_-_94964209 0.190 NM_144665
SESN3
sestrin 3
chr12_-_22487566 0.188 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr11_-_120008738 0.187 TRIM29
tripartite motif containing 29
chr15_+_60296420 0.187 NM_012182
FOXB1
forkhead box B1
chr7_+_30324611 0.185 ZNRF2
zinc and ring finger 2
chr18_-_28681885 0.183 NM_004949
NM_024422
DSC2

desmocollin 2

chr9_+_12774988 0.182 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr5_-_175964223 0.182 NM_014901
RNF44
ring finger protein 44
chr1_+_153747767 0.181 NM_024330
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr19_+_35739778 0.180 LSR
lipolysis stimulated lipoprotein receptor
chr17_+_36507708 0.177 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr11_+_58939960 0.177 DTX4
deltex homolog 4 (Drosophila)
chr9_-_131940538 0.177 NM_203434
IER5L
immediate early response 5-like
chr2_+_30454396 0.176 NM_030915
LBH
limb bud and heart development homolog (mouse)
chrX_-_51239426 0.176 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr1_-_9970265 0.175 NM_001012329
NM_020248
CTNNBIP1

catenin, beta interacting protein 1

chr1_+_27668462 0.172 NM_001193308
NM_032872
SYTL1

synaptotagmin-like 1

chr7_+_150811719 0.171 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr13_+_42031525 0.170 NM_014059
C13orf15
chromosome 13 open reading frame 15
chrX_-_51239295 0.168 NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr2_-_174829951 0.168 SP3
Sp3 transcription factor
chr19_+_1103935 0.166 NM_001039847
NM_002085
GPX4

glutathione peroxidase 4 (phospholipid hydroperoxidase)

chr2_-_46384 0.166 NM_001077710
FAM110C
family with sequence similarity 110, member C
chrX_-_153707217 0.165 LAGE3
L antigen family, member 3
chr14_+_24867926 0.165 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr1_+_109792640 0.163 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr6_+_30851860 0.163 NM_001954
DDR1
discoidin domain receptor tyrosine kinase 1
chr19_+_41281281 0.162 NM_006533
MIA
melanoma inhibitory activity
chr16_+_68679229 0.162 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr19_+_45281125 0.162 NM_001130852
NM_012116
CBLC

Cas-Br-M (murine) ecotropic retroviral transforming sequence c

chr6_+_89790464 0.160 PNRC1
proline-rich nuclear receptor coactivator 1
chr1_-_154531083 0.159 NM_017582
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr9_-_139948448 0.157 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr9_-_131940481 0.154 IER5L
immediate early response 5-like
chr1_+_226250413 0.153 H3F3A
H3 histone, family 3A
chr7_+_145813452 0.152 NM_014141
CNTNAP2
contactin associated protein-like 2
chr5_+_75699003 0.149 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr19_-_49567123 0.148 NM_006179
NTF4
neurotrophin 4
chr6_-_111894897 0.147 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr14_-_21572789 0.147 NM_001102454
ZNF219
zinc finger protein 219
chr13_+_28366779 0.144 NM_145657
GSX1
GS homeobox 1
chr3_+_142895132 0.143


chr1_-_935469 0.143 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr1_+_2005083 0.143 NM_001033581
PRKCZ
protein kinase C, zeta
chr15_-_83621350 0.142 NM_004839
NM_199330
HOMER2

homer homolog 2 (Drosophila)

chr9_-_138591318 0.141 NM_001012415
NM_001101677
SOHLH1

spermatogenesis and oogenesis specific basic helix-loop-helix 1

chr17_+_48610045 0.141 NM_017957
EPN3
epsin 3
chr16_-_81110803 0.139 NM_001100873
NM_152337
C16orf46

chromosome 16 open reading frame 46

chr1_+_200863948 0.138 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr6_-_91006580 0.138 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr6_+_83903031 0.137 NM_033411
RWDD2A
RWD domain containing 2A
chr8_+_145159398 0.135 MAF1
MAF1 homolog (S. cerevisiae)
chr6_+_31430955 0.133 HCP5
HLA complex P5 (non-protein coding)
chr8_+_145159304 0.132 NM_032272
MAF1
MAF1 homolog (S. cerevisiae)
chr11_+_1886394 0.131 NM_001242932
LSP1
lymphocyte-specific protein 1
chr1_+_27320132 0.129 NM_001013642
TRNP1
TMF1-regulated nuclear protein 1
chr1_-_54871681 0.128 SSBP3
single stranded DNA binding protein 3
chr17_+_39261640 0.128 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr14_+_61788398 0.128 NM_006255
PRKCH
protein kinase C, eta
chr13_+_42031690 0.127 C13orf15
chromosome 13 open reading frame 15
chr2_+_30369868 0.127 YPEL5
yippee-like 5 (Drosophila)
chr20_-_35807884 0.126 NM_152503
NM_213631
NM_213632
C20orf132


chromosome 20 open reading frame 132


chr22_+_31644368 0.126 LIMK2
LIM domain kinase 2
chr11_+_1889902 0.126 NM_001013253
LSP1
lymphocyte-specific protein 1
chr14_-_90085325 0.125 NM_001085471
FOXN3
forkhead box N3
chr17_-_74581934 0.125 ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr16_+_30907927 0.124 NM_001142544
NM_001330
CTF1

cardiotrophin 1

chrX_+_70315637 0.124 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr4_+_3465032 0.124 NM_001164673
NM_173660
DOK7

docking protein 7

chr15_+_101420032 0.123 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr2_-_220436010 0.123 OBSL1
obscurin-like 1
chr12_+_54378929 0.122 NM_017409
HOXC10
homeobox C10
chr19_-_14201230 0.122 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr22_+_39473009 0.122 NM_021822
APOBEC3G
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
chr18_+_33877630 0.121 NM_025135
FHOD3
formin homology 2 domain containing 3
chr17_-_42201009 0.120 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr18_-_52626636 0.120 NM_025214
CCDC68
coiled-coil domain containing 68
chr7_+_40174594 0.119 C7orf10
chromosome 7 open reading frame 10
chr12_-_56101667 0.119 NM_001144996
NM_002206
ITGA7

integrin, alpha 7

chr17_+_39382878 0.119 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr8_-_75233461 0.117 NM_020647
JPH1
junctophilin 1
chr17_-_39222126 0.116 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr6_+_26124372 0.116 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr21_-_46237974 0.116 SUMO3
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
chr12_-_49351263 0.116


chr2_+_30369749 0.115 NM_001127399
NM_001127400
NM_001127401
NM_016061
YPEL5



yippee-like 5 (Drosophila)



chr12_+_120972155 0.115 RNF10
ring finger protein 10
chr7_+_100860960 0.115 NM_006349
ZNHIT1
zinc finger, HIT-type containing 1
chr17_-_74582144 0.114 NM_006456
ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr11_-_124767681 0.114 NM_019055
ROBO4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr1_+_200860619 0.113 NM_018265
C1orf106
chromosome 1 open reading frame 106
chr8_+_95653340 0.113 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr6_+_42928464 0.112 NM_018960
GNMT
glycine N-methyltransferase
chr1_+_33231260 0.112 KIAA1522
KIAA1522
chr19_-_36523770 0.111 NM_015526
CLIP3
CAP-GLY domain containing linker protein 3
chr9_-_98270830 0.111 NM_000264
PTCH1
patched 1
chr19_-_41933255 0.111


chr1_+_33231227 0.111 NM_001198972
NM_001198973
KIAA1522

KIAA1522

chr6_+_42981955 0.111 KLHDC3
kelch domain containing 3
chr17_+_73717515 0.110 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr1_-_160990862 0.110 F11R
F11 receptor
chr1_-_144520987 0.109 LOC728855
uncharacterized LOC728855
chr14_+_96342728 0.109 LOC100507043
uncharacterized LOC100507043
chr16_+_29690328 0.109 NM_014298
QPRT
quinolinate phosphoribosyltransferase
chr14_-_21566728 0.108 NM_016423
ZNF219
zinc finger protein 219
chr19_-_36004553 0.108 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr2_+_185463235 0.107 ZNF804A
zinc finger protein 804A
chr8_+_95653399 0.107 ESRP1
epithelial splicing regulatory protein 1
chr22_-_45636584 0.106 NM_001009880
KIAA0930
KIAA0930
chr7_+_73442451 0.105 ELN
elastin
chr11_+_45944155 0.105 GYLTL1B
glycosyltransferase-like 1B
chr11_-_2019070 0.105 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr19_-_49140569 0.105 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr11_+_58939539 0.104 NM_015177
DTX4
deltex homolog 4 (Drosophila)
chr12_-_6798619 0.104 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr17_-_7197896 0.104 YBX2
Y box binding protein 2
chr11_-_130184314 0.104 ZBTB44
zinc finger and BTB domain containing 44
chr2_-_193059249 0.103 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr4_-_120549115 0.103 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr17_+_73717596 0.103 ITGB4
integrin, beta 4
chr5_-_60140041 0.102 NM_001104558
NM_024930
ELOVL7

ELOVL fatty acid elongase 7

chr17_-_39780762 0.102 NM_000422
KRT17
keratin 17
chr19_-_47922339 0.102 MEIS3
Meis homeobox 3
chr19_-_6110491 0.102 RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr6_-_116381765 0.102 NM_002031
FRK
fyn-related kinase
chr7_+_129008044 0.102 AHCYL2
adenosylhomocysteinase-like 2
chr14_-_21567069 0.101 NM_001101672
ZNF219
zinc finger protein 219
chr17_+_73717556 0.101 ITGB4
integrin, beta 4
chr18_+_11689135 0.101 NM_182978
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr8_-_17658385 0.100 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr1_+_155051263 0.100 NM_004952
EFNA3
ephrin-A3
chr12_+_41086189 0.100 NM_001843
NM_175038
CNTN1

contactin 1

chr1_-_153588789 0.100 NM_020672
S100A14
S100 calcium binding protein A14
chr16_-_30107492 0.099 NM_031477
NM_001145524
YPEL3

yippee-like 3 (Drosophila)

chr19_+_16059817 0.099 NM_001004465
OR10H4
olfactory receptor, family 10, subfamily H, member 4
chr6_+_89791510 0.099 PNRC1
proline-rich nuclear receptor coactivator 1
chr22_+_39436608 0.099 NM_001006666
NM_145298
APOBEC3F

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F

chr9_-_94124194 0.098 NM_001698
AUH
AU RNA binding protein/enoyl-CoA hydratase
chr6_+_79787548 0.097 PHIP
pleckstrin homology domain interacting protein
chr7_+_40174480 0.097 NM_001193311
NM_001193312
NM_001193313
NM_024728
C7orf10



chromosome 7 open reading frame 10



chr3_-_171528227 0.097 NM_001130081
NM_002662
PLD1

phospholipase D1, phosphatidylcholine-specific

chr12_+_72057676 0.097 NM_031435
THAP2
THAP domain containing, apoptosis associated protein 2
chr6_+_107811272 0.097 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr9_-_80646150 0.097 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr1_+_16083132 0.096 FBLIM1
filamin binding LIM protein 1
chr12_+_10365415 0.096 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr14_-_23652840 0.096 NM_012244
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr18_-_24129084 0.095 NM_001136205
KCTD1
potassium channel tetramerisation domain containing 1
chr6_+_42981986 0.095 KLHDC3
kelch domain containing 3
chr3_-_48470715 0.095 NM_002673
PLXNB1
plexin B1
chr7_-_150945731 0.095 NM_001003801
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_-_160990971 0.095 NM_016946
F11R
F11 receptor
chr11_-_2018703 0.095 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr1_+_206730497 0.095 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr7_-_143105897 0.094 NM_005232
EPHA1
EPH receptor A1
chr6_-_82461857 0.094 FAM46A
family with sequence similarity 46, member A
chr5_+_139027868 0.094 CXXC5
CXXC finger protein 5
chr7_+_73442486 0.094 ELN
elastin
chr1_-_201438150 0.093 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr12_-_49351240 0.093 ARF3
ADP-ribosylation factor 3
chr10_-_97050671 0.093 NM_020992
PDLIM1
PDZ and LIM domain 1
chr12_-_58160823 0.093 NM_000785
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr3_+_42700837 0.092 ZBTB47
zinc finger and BTB domain containing 47
chr1_+_226250421 0.092 H3F3A
H3F3AP4
H3 histone, family 3A
H3 histone, family 3A, pseudogene 4
chr19_+_54385429 0.092 NM_002739
PRKCG
protein kinase C, gamma
chr10_-_50970321 0.092 NM_001143996
NM_001143997
NM_018245
OGDHL


oxoglutarate dehydrogenase-like


chr1_+_38273817 0.092 C1orf122
chromosome 1 open reading frame 122
chr1_+_206730456 0.092 NM_182665
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr17_+_7255427 0.091 KCTD11
potassium channel tetramerisation domain containing 11
chr12_+_57482886 0.091 NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr22_+_31644314 0.091 NM_001031801
NM_016733
LIMK2

LIM domain kinase 2

chr17_-_27949814 0.091 CORO6
coronin 6
chr21_-_46237978 0.090 SUMO3
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
chr2_+_23608297 0.090 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr19_+_1104068 0.090 GPX4
glutathione peroxidase 4 (phospholipid hydroperoxidase)
chr17_-_40264687 0.089 NM_024119
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr14_-_23652818 0.089 SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr11_+_121322848 0.089 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.18 2.52e-15 GO:0050794 regulation of cellular process
1.16 2.40e-14 GO:0050789 regulation of biological process
1.15 9.18e-14 GO:0065007 biological regulation
1.25 1.91e-12 GO:0023052 signaling
1.42 2.24e-11 GO:0007399 nervous system development
1.26 2.51e-11 GO:0007165 signal transduction
1.09 6.32e-11 GO:0009987 cellular process
1.52 1.05e-09 GO:0022008 neurogenesis
1.53 1.14e-09 GO:0048699 generation of neurons
1.46 4.65e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.25 6.08e-08 GO:0048731 system development
1.38 1.10e-07 GO:0035556 intracellular signal transduction
1.23 1.32e-07 GO:0048856 anatomical structure development
1.54 1.50e-07 GO:0030182 neuron differentiation
1.60 1.53e-07 GO:0048666 neuron development
1.29 2.25e-07 GO:0048869 cellular developmental process
1.19 3.68e-07 GO:0051716 cellular response to stimulus
1.29 3.71e-07 GO:0030154 cell differentiation
1.55 4.45e-07 GO:0030030 cell projection organization
1.34 4.92e-07 GO:0009653 anatomical structure morphogenesis
1.70 8.82e-07 GO:0007264 small GTPase mediated signal transduction
1.65 1.76e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.25 2.11e-06 GO:0048519 negative regulation of biological process
1.19 2.14e-06 GO:0032502 developmental process
1.23 2.77e-06 GO:0048518 positive regulation of biological process
1.60 3.14e-06 GO:0031175 neuron projection development
1.63 3.18e-06 GO:0048812 neuron projection morphogenesis
1.59 3.82e-06 GO:0000904 cell morphogenesis involved in differentiation
1.26 4.11e-06 GO:0048523 negative regulation of cellular process
1.64 4.39e-06 GO:0007409 axonogenesis
1.29 5.05e-06 GO:0007166 cell surface receptor linked signaling pathway
1.20 5.51e-06 GO:0007275 multicellular organismal development
1.50 1.58e-05 GO:0032989 cellular component morphogenesis
1.69 2.18e-05 GO:0007411 axon guidance
1.55 2.31e-05 GO:0032990 cell part morphogenesis
1.17 2.69e-05 GO:0019222 regulation of metabolic process
1.23 3.17e-05 GO:0048522 positive regulation of cellular process
1.40 4.07e-05 GO:0048468 cell development
1.55 4.23e-05 GO:0048858 cell projection morphogenesis
1.18 7.31e-05 GO:0031323 regulation of cellular metabolic process
1.49 7.50e-05 GO:0000902 cell morphogenesis
1.18 1.07e-04 GO:0080090 regulation of primary metabolic process
1.36 2.08e-04 GO:0006793 phosphorus metabolic process
1.36 2.08e-04 GO:0006796 phosphate metabolic process
1.39 2.10e-04 GO:0040011 locomotion
1.18 2.84e-04 GO:0060255 regulation of macromolecule metabolic process
1.46 3.31e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.42 9.52e-04 GO:0051254 positive regulation of RNA metabolic process
1.39 1.04e-03 GO:2000026 regulation of multicellular organismal development
1.35 1.12e-03 GO:0050793 regulation of developmental process
1.42 1.20e-03 GO:0010628 positive regulation of gene expression
1.29 1.84e-03 GO:0051239 regulation of multicellular organismal process
1.36 2.21e-03 GO:0016310 phosphorylation
1.35 2.28e-03 GO:0006351 transcription, DNA-dependent
1.19 2.30e-03 GO:0010468 regulation of gene expression
1.87 2.60e-03 GO:0046039 GTP metabolic process
1.21 2.90e-03 GO:0051252 regulation of RNA metabolic process
1.46 3.65e-03 GO:0006935 chemotaxis
1.46 3.65e-03 GO:0042330 taxis
1.88 3.84e-03 GO:0006184 GTP catabolic process
1.58 4.36e-03 GO:0060284 regulation of cell development
1.47 6.52e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.18 7.40e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 8.25e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.29 8.61e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.43 9.64e-03 GO:0051253 negative regulation of RNA metabolic process
1.67 9.77e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.36 1.17e-02 GO:0006468 protein phosphorylation
1.35 1.18e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.20 1.22e-02 GO:0006355 regulation of transcription, DNA-dependent
1.42 1.27e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.17 1.56e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.46 1.73e-02 GO:0032583 regulation of gene-specific transcription
1.35 1.83e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 1.94e-02 GO:0009893 positive regulation of metabolic process
1.57 2.91e-02 GO:0051960 regulation of nervous system development
1.82 2.98e-02 GO:0016055 Wnt receptor signaling pathway
2.51 3.15e-02 GO:0045995 regulation of embryonic development
1.17 3.33e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.21 3.33e-02 GO:0048583 regulation of response to stimulus
1.37 3.48e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.36 3.75e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.29 3.85e-02 GO:0032774 RNA biosynthetic process
1.32 3.99e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.17 4.58e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.18 4.62e-02 GO:0042221 response to chemical stimulus
1.26 4.66e-02 GO:0031325 positive regulation of cellular metabolic process
1.22 4.75e-02 GO:0023051 regulation of signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 6.94e-11 GO:0005737 cytoplasm
1.08 1.54e-10 GO:0005622 intracellular
1.08 5.87e-10 GO:0044424 intracellular part
1.07 1.75e-04 GO:0043229 intracellular organelle
1.07 1.84e-04 GO:0043226 organelle
1.11 7.71e-04 GO:0005634 nucleus
1.19 3.38e-03 GO:0005829 cytosol
1.37 6.49e-03 GO:0030054 cell junction
1.07 1.00e-02 GO:0043231 intracellular membrane-bounded organelle
1.07 1.36e-02 GO:0043227 membrane-bounded organelle
1.17 1.90e-02 GO:0044459 plasma membrane part
1.20 2.74e-02 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 1.50e-14 GO:0005515 protein binding
1.08 1.39e-10 GO:0005488 binding
1.45 7.04e-09 GO:0001071 nucleic acid binding transcription factor activity
1.45 7.04e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.50 1.88e-05 GO:0008092 cytoskeletal protein binding
1.44 2.84e-05 GO:0043565 sequence-specific DNA binding
1.33 1.80e-04 GO:0030528 transcription regulator activity
1.34 2.69e-03 GO:0016301 kinase activity
1.33 9.16e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.29 9.98e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.45 2.26e-02 GO:0019001 guanyl nucleotide binding
1.45 2.26e-02 GO:0032561 guanyl ribonucleotide binding
1.51 2.33e-02 GO:0008134 transcription factor binding
1.45 2.62e-02 GO:0005525 GTP binding
1.47 4.10e-02 GO:0003779 actin binding
1.33 4.84e-02 GO:0004672 protein kinase activity