Motif ID: STAT1,3.p3

Z-value: 0.667


Transcription factors associated with STAT1,3.p3:

Gene SymbolEntrez IDGene Name
STAT1 6772 signal transducer and activator of transcription 1, 91kDa
STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT1chr2_-_1918723220.791.9e-02Click!
STAT3chr17_-_405404910.667.8e-02Click!


Activity profile for motif STAT1,3.p3.

activity profile for motif STAT1,3.p3


Sorted Z-values histogram for motif STAT1,3.p3

Sorted Z-values for motif STAT1,3.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT1,3.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_55515468 2.277 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr11_+_62104882 0.755 ASRGL1
asparaginase like 1
chr1_-_144994908 0.593 PDE4DIP
phosphodiesterase 4D interacting protein
chr11_+_62104773 0.586 NM_001083926
NM_025080
ASRGL1

asparaginase like 1

chr1_-_144994943 0.583 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr19_+_44529493 0.478 NM_001129996
NM_013360
ZNF284
ZNF222

zinc finger protein 284
zinc finger protein 222

chr10_-_90750955 0.462 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr18_-_52626636 0.439 NM_025214
CCDC68
coiled-coil domain containing 68
chr14_-_92414004 0.416 NM_006329
FBLN5
fibulin 5
chr22_-_31503484 0.413 NM_080430
SELM
selenoprotein M
chr19_+_44764032 0.403 NM_001207005
NM_181756
ZNF233

zinc finger protein 233

chr1_-_144994839 0.391 PDE4DIP
phosphodiesterase 4D interacting protein
chr19_-_44809126 0.370 NM_004234
ZNF235
zinc finger protein 235
chr10_+_95848811 0.368 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr8_+_27183062 0.356 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr16_-_3109335 0.352 LOC100507419
uncharacterized LOC100507419
chr11_+_114167168 0.314 NNMT
nicotinamide N-methyltransferase
chr11_+_114167197 0.305 NNMT
nicotinamide N-methyltransferase
chr14_+_24836144 0.293 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr3_+_185000714 0.274 NM_001242314
NM_001242317
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr19_+_44645728 0.272 ZNF234
zinc finger protein 234
chr16_-_24968856 0.265 ARHGAP17
Rho GTPase activating protein 17
chr19_-_44952630 0.263 NM_014518
ZNF229
zinc finger protein 229
chr4_-_129209983 0.259 NM_006320
PGRMC2
progesterone receptor membrane component 2
chr12_-_8380193 0.258 NM_018088
FAM90A1
family with sequence similarity 90, member A1
chr19_+_44716683 0.239 NM_182490
ZNF227
zinc finger protein 227
chr6_-_27440459 0.236 NM_007149
ZNF184
zinc finger protein 184
chr15_+_43622871 0.227 NM_001012969
NM_001159280
ADAL

adenosine deaminase-like

chr6_-_31698033 0.218 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr1_+_156084579 0.212 LMNA
lamin A/C
chr16_-_67260720 0.210 NM_012163
LRRC29
leucine rich repeat containing 29
chr4_+_126237566 0.206 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr15_+_90808833 0.200 NM_001033088
NGRN
neugrin, neurite outgrowth associated
chr19_-_56904869 0.199 NM_144690
ZNF582
zinc finger protein 582
chr10_+_90751044 0.192 FAS
Fas (TNF receptor superfamily, member 6)
chr17_-_11900688 0.186 NM_144680
ZNF18
zinc finger protein 18
chr7_+_80275634 0.185 NM_001127443
NM_001127444
CD36

CD36 molecule (thrombospondin receptor)

chr5_-_133706717 0.182 CDKL3
cyclin-dependent kinase-like 3
chr6_+_36646455 0.176 NM_000389
NM_001220778
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr19_+_44617510 0.173 NM_013362
ZNF225
zinc finger protein 225
chr5_+_133706869 0.170 NM_003337
UBE2B
ubiquitin-conjugating enzyme E2B
chr17_-_76356153 0.170 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr19_-_893215 0.170 NM_005481
MED16
mediator complex subunit 16
chr6_-_111136616 0.161 CDK19
cyclin-dependent kinase 19
chr4_-_21546278 0.161 NM_001035004
KCNIP4
Kv channel interacting protein 4
chr15_+_33010174 0.160 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr19_+_49977817 0.159 NM_001204503
FLT3LG
fms-related tyrosine kinase 3 ligand
chr5_+_133707105 0.156 UBE2B
ubiquitin-conjugating enzyme E2B
chr19_+_44576266 0.156 NM_001037813
ZNF284
zinc finger protein 284
chr8_+_96037186 0.154 NM_152416
C8orf38
chromosome 8 open reading frame 38
chr9_+_136287119 0.154 NM_139025
NM_139026
NM_139027
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr19_-_51845377 0.153 NM_001163922
VSIG10L
V-set and immunoglobulin domain containing 10 like
chr3_+_12330336 0.152 NM_138711
PPARG
peroxisome proliferator-activated receptor gamma
chr3_-_15900928 0.152 NM_015199
ANKRD28
ankyrin repeat domain 28
chr2_+_166150340 0.145 NM_021007
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chrX_+_102862833 0.144 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr19_+_44507076 0.143 NM_006300
ZNF230
zinc finger protein 230
chr3_+_122399665 0.142 NM_017554
PARP14
poly (ADP-ribose) polymerase family, member 14
chr19_-_893184 0.142 MED16
mediator complex subunit 16
chr22_-_50699687 0.137 MAPK12
mitogen-activated protein kinase 12
chr16_-_67260900 0.137 NM_001004055
LRRC29
leucine rich repeat containing 29
chr9_-_86571652 0.132 NM_032307
C9orf64
chromosome 9 open reading frame 64
chr16_-_74455239 0.131 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr5_+_55062712 0.131 NM_001166534
DDX4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr14_-_68141328 0.131 NM_006370
VTI1B
vesicle transport through interaction with t-SNAREs homolog 1B (yeast)
chr19_+_17530841 0.130 FAM125A
family with sequence similarity 125, member A
chr19_+_58144510 0.130 NM_006385
NM_198855
ZNF211

zinc finger protein 211

chr5_+_134209426 0.129 NM_024715
TXNDC15
thioredoxin domain containing 15
chr19_+_17530856 0.126 NM_138401
FAM125A
family with sequence similarity 125, member A
chr9_+_130186652 0.123 NM_007135
ZNF79
zinc finger protein 79
chr3_-_170626425 0.123 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr1_-_11918889 0.120 NM_002521
NPPB
natriuretic peptide B
chr9_+_130186714 0.116 ZNF79
zinc finger protein 79
chr10_+_91152321 0.114 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr19_+_44488331 0.109 NM_003445
NM_198089
ZNF155

zinc finger protein 155

chr1_-_163113938 0.108 RGS5
regulator of G-protein signaling 5
chr19_+_44556163 0.108 NM_013361
ZNF223
zinc finger protein 223
chr6_+_36646489 0.107 CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr5_-_177659800 0.106 NM_153373
AGXT2L2
alanine-glyoxylate aminotransferase 2-like 2
chr9_+_139877444 0.103 NM_207510
LCNL1
lipocalin-like 1
chr20_+_61436160 0.101 NM_007346
OGFR
opioid growth factor receptor
chr19_+_44598479 0.099 NM_013398
ZNF224
zinc finger protein 224
chr12_-_75603214 0.097 KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr16_+_70207927 0.095 NM_173619
CLEC18C
CLEC18A
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
chr6_-_35696359 0.094 NM_001145775
FKBP5
FK506 binding protein 5
chr8_-_27168783 0.091 NM_171982
TRIM35
tripartite motif containing 35
chr13_+_99058147 0.090


chr5_-_177659753 0.090 AGXT2L2
alanine-glyoxylate aminotransferase 2-like 2
chr14_-_20881577 0.088 NM_007110
TEP1
telomerase-associated protein 1
chr5_-_139943829 0.088 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr16_-_66952729 0.087 NM_001204744
NM_001204745
NM_001204746
NM_004062
CDH16



cadherin 16, KSP-cadherin



chr19_-_14049167 0.087 NM_024825
PODNL1
podocan-like 1
chr19_+_35168558 0.082 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr3_-_187871816 0.081 LPP-AS2
LPP antisense RNA 2 (non-protein coding)
chr19_+_40502942 0.081 NM_178544
ZNF546
zinc finger protein 546
chr2_-_20101614 0.081 NM_001008237
TTC32
tetratricopeptide repeat domain 32
chr6_-_28304151 0.078 NM_001243241
NM_001243242
NM_001243244
NM_030899
ZNF323



zinc finger protein 323



chr12_-_54070108 0.078 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr19_-_49149252 0.077 NM_001217
CA11
carbonic anhydrase XI
chr19_-_55874607 0.076 NM_001145402
FAM71E2
family with sequence similarity 71, member E2
chrX_+_119738542 0.076 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr5_-_138725544 0.076 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr22_-_41636855 0.076 NM_138481
CHADL
chondroadherin-like
chr6_+_31913852 0.075 CFB
complement factor B
chr2_+_170366211 0.070 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr11_+_130318457 0.066 NM_139055
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr1_+_196621007 0.065 NM_000186
NM_001014975
CFH

complement factor H

chr15_+_91499969 0.065 RCCD1
RCC1 domain containing 1
chr19_+_49977465 0.065 NM_001204502
NM_001459
FLT3LG

fms-related tyrosine kinase 3 ligand

chr5_-_139944045 0.064 NM_006051
NM_133172
NM_133173
NM_133174
APBB3



amyloid beta (A4) precursor protein-binding, family B, member 3



chr22_-_19842337 0.062 C22orf29
chromosome 22 open reading frame 29
chr16_-_30798206 0.062 NM_001080417
ZNF629
zinc finger protein 629
chr8_+_36641841 0.061 NM_001031836
KCNU1
potassium channel, subfamily U, member 1
chr11_+_46694514 0.061 ATG13
ATG13 autophagy related 13 homolog (S. cerevisiae)
chr6_-_132722564 0.061 NM_015529
MOXD1
monooxygenase, DBH-like 1
chr5_+_149887673 0.058 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr2_-_20101392 0.058


chr4_+_130017281 0.058 NM_001099783
C4orf33
chromosome 4 open reading frame 33
chr5_-_177659551 0.057 AGXT2L2
alanine-glyoxylate aminotransferase 2-like 2
chr4_+_148402244 0.057 EDNRA
endothelin receptor type A
chr3_+_48481706 0.056 CCDC72
coiled-coil domain containing 72
chr12_-_7261788 0.055 NM_016546
C1RL
complement component 1, r subcomponent-like
chr11_+_65268313 0.052 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr17_-_76183074 0.051 NM_003258
TK1
thymidine kinase 1, soluble
chr4_+_52709165 0.051 NM_001040402
NM_015115
DCUN1D4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr1_-_42630386 0.050 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr6_+_31540092 0.049 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr16_+_2802683 0.049 SRRM2
serine/arginine repetitive matrix 2
chr6_-_111136330 0.049 CDK19
cyclin-dependent kinase 19
chr3_-_61237036 0.049 NM_001166243
NM_002012
FHIT

fragile histidine triad gene

chr10_+_93558182 0.048 TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr5_+_175875372 0.048 FAF2
Fas associated factor family member 2
chr19_-_38720312 0.048 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr10_+_65224937 0.047 LOC84989
uncharacterized LOC84989
chr17_+_5323471 0.047 RPAIN
RPA interacting protein
chr9_-_86571631 0.047 C9orf64
chromosome 9 open reading frame 64
chr12_-_56211503 0.046 SARNP
SAP domain containing ribonucleoprotein
chr3_-_170626381 0.044 EIF5A2
eukaryotic translation initiation factor 5A2
chr3_-_81810618 0.044 GBE1
glucan (1,4-alpha-), branching enzyme 1
chrX_+_48432740 0.044 NM_006743
RBM3
RNA binding motif (RNP1, RRM) protein 3
chr6_-_111136506 0.043 CDK19
cyclin-dependent kinase 19
chr19_-_3984152 0.043 EEF2
eukaryotic translation elongation factor 2
chr11_+_36616039 0.042 NM_138787
C11orf74
chromosome 11 open reading frame 74
chr15_-_43802666 0.042 NM_005657
TP53BP1
tumor protein p53 binding protein 1
chr16_+_4674829 0.042 MGRN1
mahogunin, ring finger 1
chr3_-_146213721 0.042 NM_001199979
PLSCR2
phospholipid scramblase 2
chr12_-_123756164 0.041 NM_004642
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr7_-_124430742 0.041 NM_001024603
LOC154872
uncharacterized LOC154872
chr19_-_14048877 0.041 PODNL1
podocan-like 1
chr16_-_56553960 0.041 NM_031885
BBS2
Bardet-Biedl syndrome 2
chr19_+_3762671 0.040 MRPL54
mitochondrial ribosomal protein L54
chr7_-_72972021 0.040 NM_001197244
NM_001707
BCL7B

B-cell CLL/lymphoma 7B

chr4_+_3443659 0.040 HGFAC
HGF activator
chr11_+_61197574 0.039 NM_017841
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr7_-_100171269 0.039 NM_001168682
SAP25
Sin3A-associated protein, 25kDa
chr22_+_18121540 0.039 BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr19_-_36980336 0.038 NM_032838
NM_001145343
NM_001145344
NM_001145345
ZNF566



zinc finger protein 566



chr10_+_74870209 0.038 NM_015901
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr12_-_56211511 0.037 NM_033082
SARNP
SAP domain containing ribonucleoprotein
chr8_-_42623928 0.037 NM_001199279
NM_004198
CHRNA6

cholinergic receptor, nicotinic, alpha 6

chr22_-_50765405 0.036 NM_001001794
FAM116B
family with sequence similarity 116, member B
chr17_+_18855477 0.036 NM_001042450
NM_152351
SLC5A10

solute carrier family 5 (sodium/glucose cotransporter), member 10

chr19_+_37959981 0.036 NM_144694
ZNF570
zinc finger protein 570
chr19_-_45004482 0.036 NM_013256
ZNF180
zinc finger protein 180
chr12_-_56211484 0.036 SARNP
SAP domain containing ribonucleoprotein
chr16_-_29910340 0.036 NM_001114099
NM_001114100
NM_001243332
NM_001243333
NM_012410
NM_201575
SEZ6L2





seizure related 6 homolog (mouse)-like 2





chr16_-_4897265 0.035 NM_032569
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr3_+_187871473 0.035 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_+_187086167 0.035 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr6_+_31913763 0.035 CFB
complement factor B
chr13_+_106118215 0.033 NM_001161814
NM_172370
DAOA

D-amino acid oxidase activator

chr3_-_81810914 0.033 NM_000158
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr17_+_71229357 0.033 C17orf80
chromosome 17 open reading frame 80
chr1_+_54519259 0.033 NM_153035
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr1_-_154946830 0.033 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr3_+_128598332 0.033 NM_014049
ACAD9
acyl-CoA dehydrogenase family, member 9
chr6_-_28303910 0.033 NM_001135216
NM_001243243
ZNF323

zinc finger protein 323

chr19_+_3762650 0.033 NM_172251
MRPL54
mitochondrial ribosomal protein L54
chr3_+_180319898 0.033 NM_001042601
NM_133462
TTC14

tetratricopeptide repeat domain 14

chr3_+_128598520 0.032 ACAD9
acyl-CoA dehydrogenase family, member 9
chr1_+_233086319 0.032 NM_032324
NTPCR
nucleoside-triphosphatase, cancer-related
chr19_-_58067724 0.032 NM_001039654
ZNF550
zinc finger protein 550
chr9_+_136287443 0.032 ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr9_-_86571533 0.032 C9orf64
chromosome 9 open reading frame 64
chr19_+_44455379 0.031 NM_013359
ZNF221
zinc finger protein 221
chr3_+_23987514 0.031 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chrX_+_106143393 0.031 NM_001171092
CLDN2
claudin 2
chr15_+_41625152 0.031 NUSAP1
nucleolar and spindle associated protein 1
chr11_-_64703334 0.031 NM_130769
GPHA2
glycoprotein hormone alpha 2
chr12_+_50505748 0.031 NM_032901
C12orf62
chromosome 12 open reading frame 62
chr17_+_32683470 0.031 NM_005408
CCL13
chemokine (C-C motif) ligand 13
chr9_+_131038500 0.030 SWI5
SWI5 recombination repair homolog (yeast)
chr4_+_3443691 0.030 NM_001528
HGFAC
HGF activator
chr3_-_169587598 0.030 NM_024727
LRRC31
leucine rich repeat containing 31
chr19_+_18530211 0.030 SSBP4
single stranded DNA binding protein 4
chr6_+_97010423 0.029 NM_001170807
NM_020482
FHL5

four and a half LIM domains 5

chr1_-_160617042 0.029 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr2_-_68384575 0.028 NM_138458
WDR92
WD repeat domain 92
chr14_+_55168831 0.028 SAMD4A
sterile alpha motif domain containing 4A
chr8_+_86157693 0.028 NM_198584
CA13
carbonic anhydrase XIII

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.