• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: TFAP2B.p2

Z-value: 1.709

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_231175971	1.429	NM_198552	FAM89A	family with sequence similarity 89, member A
chr2_+_47596447	1.339		EPCAM	epithelial cell adhesion molecule
chrX_+_152953751	1.146	NM_001142805 NM_005629	SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr6_-_99797530	1.099	NM_032511	C6orf168	chromosome 6 open reading frame 168
chr2_+_47596286	1.092	NM_002354	EPCAM	epithelial cell adhesion molecule
chr15_+_80987609	1.026	NM_021214	FAM108C1	family with sequence similarity 108, member C1
chr22_+_45098091	1.008	NM_181334	PRR5-ARHGAP8 PRR5	PRR5-ARHGAP8 readthrough proline rich 5 (renal)
chr14_-_105634708	0.999		JAG2	jagged 2
chr4_+_1795004	0.989	NM_000142 NM_001163213 NM_022965	FGFR3	fibroblast growth factor receptor 3
chr22_-_43583132	0.987	NM_015140	TTLL12	tubulin tyrosine ligase-like family, member 12
chr22_+_51113069	0.888	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr9_-_100954883	0.861	NM_052820	CORO2A	coronin, actin binding protein, 2A
chr17_+_30813928	0.806	NM_003885	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr2_+_75061234	0.802		HK2	hexokinase 2
chr7_+_4722091	0.798		FOXK1	forkhead box K1
chr17_+_9548853	0.764	NM_153210	USP43	ubiquitin specific peptidase 43
chr13_-_99229037	0.763		STK24	serine/threonine kinase 24
chr6_+_4776826	0.748		CDYL	chromodomain protein, Y-like
chr6_+_71998476	0.743	NM_024576	OGFRL1	opioid growth factor receptor-like 1
chr6_+_71998508	0.743		OGFRL1	opioid growth factor receptor-like 1
chr22_-_43583058	0.720		TTLL12	tubulin tyrosine ligase-like family, member 12
chr16_-_87903028	0.710	NM_003486	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr18_+_33877630	0.679	NM_025135	FHOD3	formin homology 2 domain containing 3
chr10_+_82213892	0.679	NM_001128309 NM_030927	TSPAN14	tetraspanin 14
chr20_+_45523505	0.671		EYA2	eyes absent homolog 2 (Drosophila)
chr10_+_82214071	0.671		TSPAN14	tetraspanin 14
chr11_+_130029773	0.666		ST14	suppression of tumorigenicity 14 (colon carcinoma)
chr7_-_44365019	0.666	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr7_+_18126543	0.660	NM_001204144	HDAC9	histone deacetylase 9
chr6_+_37137882	0.656	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr8_+_61591239	0.655	NM_017780	CHD7	chromodomain helicase DNA binding protein 7
chr9_-_124990949	0.655	NM_014368 NM_199160	LHX6	LIM homeobox 6
chr14_+_29236171	0.650	NM_005249	FOXG1	forkhead box G1
chr6_+_71998514	0.641		OGFRL1	opioid growth factor receptor-like 1
chr14_-_105635114	0.627	NM_002226 NM_145159	JAG2	jagged 2
chr20_+_45523247	0.615	NM_005244 NM_172110	EYA2	eyes absent homolog 2 (Drosophila)
chr14_-_95786095	0.612	NM_024734	CLMN	calmin (calponin-like, transmembrane)
chr9_+_138371627	0.607	NM_014811	PPP1R26	protein phosphatase 1, regulatory subunit 26
chr8_-_41166931	0.602	NM_003012	SFRP1	secreted frizzled-related protein 1
chr9_+_137979513	0.591		OLFM1	olfactomedin 1
chr10_+_134210691	0.587	NM_001098637 NM_138499	PWWP2B	PWWP domain containing 2B
chr1_+_26856259	0.584		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_+_8924822	0.582	NM_004822	NTN1	netrin 1
chr2_-_70781146	0.572	NM_001099691 NM_003236	TGFA	transforming growth factor, alpha
chr14_-_99947080	0.569		SETD3	SET domain containing 3
chr8_+_120220554	0.567	NM_052886	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr10_+_82214074	0.564		TSPAN14	tetraspanin 14
chr1_+_955609	0.564		AGRN	agrin
chr6_-_136871542	0.558		MAP7	microtubule-associated protein 7
chr7_-_994008	0.555		ADAP1	ArfGAP with dual PH domains 1
chr1_+_1981902	0.553	NM_002744	PRKCZ	protein kinase C, zeta
chr1_+_955536	0.548
chr1_+_955468	0.544	NM_198576	AGRN	agrin
chr8_-_28243589	0.544		ZNF395	zinc finger protein 395
chr2_-_240322692	0.539		HDAC4	histone deacetylase 4
chr3_-_185542807	0.538	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr13_-_99229117	0.537		STK24	serine/threonine kinase 24
chr20_-_60640842	0.536	NM_003185	TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr14_-_105262078	0.533	NM_001014431 NM_001014432	AKT1	v-akt murine thymoma viral oncogene homolog 1
chr16_-_85784628	0.529	NM_206967	C16orf74	chromosome 16 open reading frame 74
chr8_+_61591358	0.527		CHD7	chromodomain helicase DNA binding protein 7
chr11_-_119234628	0.526		USP2	ubiquitin specific peptidase 2
chr2_+_106361404	0.524	NM_001004722 NM_003581	NCK2	NCK adaptor protein 2
chr3_-_185542744	0.523		IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr2_+_18059923	0.521	NM_002252	KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr9_-_139948448	0.518	NM_001246 NM_203468	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2
chr5_+_167718485	0.518	NM_001161661 NM_001161662 NM_015238	WWC1	WW and C2 domain containing 1
chr2_-_235405692	0.517	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr12_+_2904289	0.509		FKBP4	FK506 binding protein 4, 59kDa
chr12_+_122459791	0.509	NM_001024808 NM_020993	BCL7A	B-cell CLL/lymphoma 7A
chr9_-_124990706	0.509	NM_001242333	LHX6	LIM homeobox 6
chr2_-_165477818	0.508		GRB14	growth factor receptor-bound protein 14
chr9_-_38069082	0.507		SHB	Src homology 2 domain containing adaptor protein B
chr14_-_105262015	0.507		AKT1	v-akt murine thymoma viral oncogene homolog 1
chr7_-_994259	0.506	NM_006869	ADAP1	ArfGAP with dual PH domains 1
chr3_+_113666544	0.501	NM_173570	ZDHHC23	zinc finger, DHHC-type containing 23
chr8_+_28559010	0.500		EXTL3	exostoses (multiple)-like 3
chr22_+_45098046	0.499	NM_181333	PRR5	proline rich 5 (renal)
chr19_-_1567875	0.497	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr8_+_28559143	0.495	NM_001440	EXTL3	exostoses (multiple)-like 3
chr8_+_56792392	0.481		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr8_-_99837768	0.480	NM_006281	STK3	serine/threonine kinase 3
chr8_+_56792345	0.478	NM_001111097 NM_002350	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_-_3456734	0.474	NM_015482	SLC22A23	solute carrier family 22, member 23
chr12_+_47473367	0.474		FAM113B	family with sequence similarity 113, member B
chr9_-_112083196	0.474		EPB41L4B	erythrocyte membrane protein band 4.1 like 4B
chr6_+_168227485	0.464	NM_001040000 NM_001207008	MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr22_+_45064323	0.463	NM_001017528 NM_001017529	PRR5	proline rich 5 (renal)
chr6_+_135502477	0.454		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr9_-_112260529	0.453	NM_001145368 NM_002829	PTPN3	protein tyrosine phosphatase, non-receptor type 3
chr1_+_160370363	0.449	NM_020335	VANGL2	vang-like 2 (van gogh, Drosophila)
chr16_+_81478774	0.448	NM_198390	CMIP	c-Maf inducing protein
chr4_-_22517339	0.445	NM_145290	GPR125	G protein-coupled receptor 125
chr2_-_70780621	0.444		TGFA	transforming growth factor, alpha
chr19_+_6531009	0.444	NM_003811	TNFSF9	tumor necrosis factor (ligand) superfamily, member 9
chr1_-_11714471	0.440		FBXO2	F-box protein 2
chr10_+_82214066	0.439		TSPAN14	tetraspanin 14
chr9_-_27529434	0.438	NM_024761	MOB3B	MOB kinase activator 3B
chr7_-_140340575	0.435		DENND2A	DENN/MADD domain containing 2A
chr11_+_45944155	0.432		GYLTL1B	glycosyltransferase-like 1B
chr9_+_137218324	0.431		RXRA	retinoid X receptor, alpha
chr7_+_69064316	0.430		AUTS2	autism susceptibility candidate 2
chr3_-_129035069	0.426	NM_006026	H1FX	H1 histone family, member X
chr18_+_10454542	0.426		APCDD1	adenomatosis polyposis coli down-regulated 1
chr19_-_663155	0.424		RNF126	ring finger protein 126
chr17_+_29718641	0.421	NM_032932	RAB11FIP4	RAB11 family interacting protein 4 (class II)
chr11_+_67033929	0.421		ADRBK1	adrenergic, beta, receptor kinase 1
chr19_-_291335	0.421	NM_003712 NM_177526	PPAP2C	phosphatidic acid phosphatase type 2C
chr11_+_68079999	0.419	NM_002335	LRP5	low density lipoprotein receptor-related protein 5
chr18_-_48723689	0.416		MEX3C	mex-3 homolog C (C. elegans)
chr1_-_33430285	0.414	NM_001127361 NM_153341	RNF19B	ring finger protein 19B
chr16_-_9057250	0.413	NM_003470	USP7	ubiquitin specific peptidase 7 (herpes virus-associated)
chr17_-_27916620	0.408		GIT1	G protein-coupled receptor kinase interacting ArfGAP 1
chr6_+_4776641	0.406	NM_004824	CDYL	chromodomain protein, Y-like
chr19_-_663158	0.406		RNF126	ring finger protein 126
chr11_+_67033889	0.406	NM_001619	ADRBK1	adrenergic, beta, receptor kinase 1
chr17_+_30814708	0.405
chr1_+_65613211	0.403	NM_203464 NM_001005353	AK4	adenylate kinase 4
chr22_-_20255614	0.400	NM_023004	RTN4R	reticulon 4 receptor
chr20_+_60697471	0.395	NM_144703	LSM14B	LSM14B, SCD6 homolog B (S. cerevisiae)
chr6_+_157099262	0.393		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr11_+_67034164	0.393		ADRBK1	adrenergic, beta, receptor kinase 1
chr22_+_38035683	0.392	NM_018957	SH3BP1	SH3-domain binding protein 1
chr18_-_78005230	0.391	NM_032510	PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)
chr15_-_72490109	0.390	NM_001012642	GRAMD2	GRAM domain containing 2
chr1_+_26856252	0.389		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr22_+_25960885	0.389		ADRBK2	adrenergic, beta, receptor kinase 2
chr5_+_892950	0.388	NM_001166260 NM_004237	TRIP13	thyroid hormone receptor interactor 13
chr14_-_91282760	0.388	NM_001010854	TTC7B	tetratricopeptide repeat domain 7B
chr1_-_54871681	0.386		SSBP3	single stranded DNA binding protein 3
chr17_+_30814552	0.386		CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr8_-_125740378	0.385		MTSS1	metastasis suppressor 1
chr11_+_67034148	0.382		ADRBK1	adrenergic, beta, receptor kinase 1
chr8_+_81398416	0.378	NM_001105539 NM_023929	ZBTB10	zinc finger and BTB domain containing 10
chr6_+_43738177	0.376		VEGFA	vascular endothelial growth factor A
chr1_+_65210724	0.376	NM_018211	RAVER2	ribonucleoprotein, PTB-binding 2
chr2_-_165477986	0.375		GRB14	growth factor receptor-bound protein 14
chr1_-_94374986	0.375	NM_002061	GCLM	glutamate-cysteine ligase, modifier subunit
chr12_+_2904101	0.375	NM_002014	FKBP4	FK506 binding protein 4, 59kDa
chr1_-_242687997	0.374	NM_152666	PLD5	phospholipase D family, member 5
chr1_-_201368434	0.371		LAD1	ladinin 1
chr1_+_26856240	0.370	NM_002953	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr7_+_128577990	0.370	NM_001098629 NM_001098630 NM_001242452	IRF5	interferon regulatory factor 5
chr9_+_132934685	0.370	NM_014286	NCS1	neuronal calcium sensor 1
chr6_+_150464156	0.368	NM_030949	PPP1R14C	protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr16_+_84682126	0.368	NM_024731	KLHL36	kelch-like 36 (Drosophila)
chr1_+_117452359	0.368	NM_020440	PTGFRN	prostaglandin F2 receptor negative regulator
chr20_+_58152563	0.366	NM_001199505	PHACTR3	phosphatase and actin regulator 3
chr2_-_46384	0.365	NM_001077710	FAM110C	family with sequence similarity 110, member C
chr6_+_157099203	0.364
chrX_-_153285334	0.361	NM_001025242 NM_001025243 NM_001569	IRAK1	interleukin-1 receptor-associated kinase 1
chr6_+_138483024	0.359	NM_020340	KIAA1244	KIAA1244
chr4_+_7194317	0.358	NM_020777	SORCS2	sortilin-related VPS10 domain containing receptor 2
chr19_-_38746978	0.357		PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr2_+_173292344	0.356		ITGA6	integrin, alpha 6
chr20_+_56285213	0.354
chr12_-_12715244	0.353	NM_030640	DUSP16	dual specificity phosphatase 16
chr11_+_33279167	0.353	NM_001048200 NM_005734	HIPK3	homeodomain interacting protein kinase 3
chr9_+_96338671	0.353	NM_005392	PHF2	PHD finger protein 2
chr17_-_27916602	0.353	NM_001085454 NM_014030	GIT1	G protein-coupled receptor kinase interacting ArfGAP 1
chr17_+_29718777	0.351		RAB11FIP4	RAB11 family interacting protein 4 (class II)
chr18_-_74207145	0.350	NM_014643	ZNF516	zinc finger protein 516
chr10_+_71390002	0.350	NM_145306	C10orf35	chromosome 10 open reading frame 35
chr16_-_402398	0.350		AXIN1	axin 1
chr2_+_102314162	0.349	NM_001242560 NM_004834 NM_145686 NM_001242559 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr17_-_16256708	0.347	NM_181716	CENPV	centromere protein V
chr12_+_93964801	0.347		SOCS2	suppressor of cytokine signaling 2
chr22_+_40390935	0.346	NM_138435	FAM83F	family with sequence similarity 83, member F
chr6_+_135502521	0.346		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr9_+_124461365	0.345		DAB2IP	DAB2 interacting protein
chrX_-_153285262	0.343		IRAK1	interleukin-1 receptor-associated kinase 1
chr10_-_100027943	0.342	NM_032211	LOXL4	lysyl oxidase-like 4
chr14_-_105261850	0.341		AKT1	v-akt murine thymoma viral oncogene homolog 1
chr13_-_101327102	0.341	NM_001079669 NM_032813	TMTC4	transmembrane and tetratricopeptide repeat containing 4
chr18_+_11981457	0.340		IMPA2	inositol(myo)-1(or 4)-monophosphatase 2
chr4_+_1723212	0.340	NM_006342	TACC3	transforming, acidic coiled-coil containing protein 3
chr2_+_85360373	0.339	NM_031283	TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)
chr4_+_128982483	0.334		LARP1B	La ribonucleoprotein domain family, member 1B
chr15_-_83953465	0.332	NM_001717	BNC1	basonuclin 1
chr15_+_80987953	0.331		FAM108C1	family with sequence similarity 108, member C1
chr2_-_165697852	0.331		COBLL1	COBL-like 1
chr7_+_150811719	0.330		AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr17_-_2614926	0.328	NM_015229	KIAA0664	KIAA0664
chr19_-_663219	0.327	NM_194460	RNF126	ring finger protein 126
chr6_+_36098261	0.325	NM_002754	MAPK13	mitogen-activated protein kinase 13
chr6_+_135502445	0.323	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr3_+_127347966	0.322	NM_015720	PODXL2	podocalyxin-like 2
chr10_-_92617670	0.321	NM_000872 NM_019859 NM_019860	HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
chr8_+_25042066	0.318		DOCK5	dedicator of cytokinesis 5
chr2_+_103236147	0.317	NM_003048	SLC9A2	solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr12_+_58148775	0.317	NM_138396	MARCH9	membrane-associated ring finger (C3HC4) 9
chr6_+_157099873	0.317		ARID1B	AT rich interactive domain 1B (SWI1-like)
chrX_+_150151757	0.316	NM_005342	HMGB3	high mobility group box 3
chr20_+_61273786	0.315	NM_016354	SLCO4A1	solute carrier organic anion transporter family, member 4A1
chr1_+_44398991	0.314	NM_001136215 NM_057090 NM_057091	ARTN	artemin
chr4_+_53728481	0.312	NM_023940	RASL11B	RAS-like, family 11, member B
chr16_-_3930713	0.312		CREBBP	CREB binding protein
chr22_+_38035718	0.310		SH3BP1	SH3-domain binding protein 1
chr13_-_99229226	0.310	NM_001032296	STK24	serine/threonine kinase 24
chr16_+_67562704	0.308	NM_024519 NM_001193522	FAM65A	family with sequence similarity 65, member A

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.10	1.45e-25	GO:0009987	cellular process
1.18	9.93e-24	GO:0044237	cellular metabolic process
1.22	6.43e-22	GO:0044260	cellular macromolecule metabolic process
1.14	7.80e-16	GO:0050794	regulation of cellular process
1.17	1.28e-14	GO:0043170	macromolecule metabolic process
1.14	4.04e-14	GO:0044238	primary metabolic process
1.13	7.71e-14	GO:0008152	metabolic process
1.12	1.63e-13	GO:0050789	regulation of biological process
1.34	4.27e-13	GO:0009966	regulation of signal transduction
1.11	5.02e-13	GO:0065007	biological regulation
1.31	1.12e-12	GO:0023051	regulation of signaling
1.29	2.16e-12	GO:0006464	protein modification process
1.19	7.08e-12	GO:0031323	regulation of cellular metabolic process
1.23	1.30e-11	GO:0044267	cellular protein metabolic process
1.27	2.90e-11	GO:0043412	macromolecule modification
1.38	4.63e-11	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.18	8.93e-11	GO:0080090	regulation of primary metabolic process
1.17	2.81e-10	GO:0019222	regulation of metabolic process
1.22	3.40e-10	GO:0048522	positive regulation of cellular process
1.18	1.16e-09	GO:0060255	regulation of macromolecule metabolic process
1.23	1.37e-09	GO:0048523	negative regulation of cellular process
1.28	4.32e-09	GO:0009653	anatomical structure morphogenesis
1.21	4.48e-09	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.20	5.23e-09	GO:0031326	regulation of cellular biosynthetic process
1.28	7.44e-09	GO:0007399	nervous system development
1.43	7.84e-09	GO:0007167	enzyme linked receptor protein signaling pathway
1.20	1.31e-08	GO:0048518	positive regulation of biological process
1.21	1.43e-08	GO:0048519	negative regulation of biological process
1.19	2.19e-08	GO:0009889	regulation of biosynthetic process
1.31	2.74e-08	GO:0010604	positive regulation of macromolecule metabolic process
1.20	3.74e-08	GO:0010556	regulation of macromolecule biosynthetic process
1.58	1.11e-07	GO:0051098	regulation of binding
1.15	1.21e-07	GO:0032502	developmental process
1.17	1.25e-07	GO:0016043	cellular component organization
1.19	1.28e-07	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.68	2.54e-07	GO:0048011	nerve growth factor receptor signaling pathway
1.16	2.80e-07	GO:0071840	cellular component organization or biogenesis
1.19	2.83e-07	GO:0010468	regulation of gene expression
1.32	2.88e-07	GO:0006793	phosphorus metabolic process
1.32	2.88e-07	GO:0006796	phosphate metabolic process
1.20	3.06e-07	GO:0051252	regulation of RNA metabolic process
1.20	3.46e-07	GO:0044249	cellular biosynthetic process
1.18	3.52e-07	GO:0051171	regulation of nitrogen compound metabolic process
1.28	3.74e-07	GO:0009893	positive regulation of metabolic process
1.29	3.87e-07	GO:0031325	positive regulation of cellular metabolic process
1.45	4.02e-07	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.15	5.52e-07	GO:0023052	signaling
1.18	7.29e-07	GO:0071842	cellular component organization at cellular level
1.18	9.21e-07	GO:0071841	cellular component organization or biogenesis at cellular level
1.16	1.18e-06	GO:0034641	cellular nitrogen compound metabolic process
1.60	1.22e-06	GO:0051101	regulation of DNA binding
1.18	1.39e-06	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38	1.48e-06	GO:0051254	positive regulation of RNA metabolic process
1.29	2.22e-06	GO:0051246	regulation of protein metabolic process
1.17	2.29e-06	GO:0019538	protein metabolic process
1.20	2.39e-06	GO:0006355	regulation of transcription, DNA-dependent
1.36	2.97e-06	GO:0009790	embryo development
1.30	3.13e-06	GO:0032268	regulation of cellular protein metabolic process
1.38	3.22e-06	GO:0045893	positive regulation of transcription, DNA-dependent
1.37	3.35e-06	GO:0031327	negative regulation of cellular biosynthetic process
1.15	3.67e-06	GO:0006807	nitrogen compound metabolic process
1.36	5.33e-06	GO:0009890	negative regulation of biosynthetic process
1.18	5.92e-06	GO:0009058	biosynthetic process
1.40	7.14e-06	GO:0051253	negative regulation of RNA metabolic process
1.34	7.30e-06	GO:0006468	protein phosphorylation
1.28	7.82e-06	GO:0010646	regulation of cell communication
1.40	7.85e-06	GO:0045892	negative regulation of transcription, DNA-dependent
1.36	8.26e-06	GO:0010628	positive regulation of gene expression
1.37	8.32e-06	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.35	8.88e-06	GO:0030182	neuron differentiation
1.31	1.04e-05	GO:0048699	generation of neurons
1.24	1.10e-05	GO:0065009	regulation of molecular function
1.33	1.40e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33	1.81e-05	GO:0010557	positive regulation of macromolecule biosynthetic process
1.30	1.86e-05	GO:0022008	neurogenesis
1.35	2.13e-05	GO:0010558	negative regulation of macromolecule biosynthetic process
1.37	2.17e-05	GO:0010629	negative regulation of gene expression
1.14	2.29e-05	GO:0007275	multicellular organismal development
1.58	2.51e-05	GO:0051090	regulation of sequence-specific DNA binding transcription factor activity
1.14	2.68e-05	GO:0007165	signal transduction
1.47	2.85e-05	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.32	3.27e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.29	3.90e-05	GO:0031324	negative regulation of cellular metabolic process
1.56	4.13e-05	GO:0090046	regulation of transcription regulator activity
1.15	4.20e-05	GO:0048856	anatomical structure development
1.21	4.68e-05	GO:0016070	RNA metabolic process
1.30	4.75e-05	GO:0031328	positive regulation of cellular biosynthetic process
1.42	6.04e-05	GO:0032583	regulation of gene-specific transcription
1.30	7.38e-05	GO:0016310	phosphorylation
1.29	9.01e-05	GO:0006351	transcription, DNA-dependent
1.19	9.58e-05	GO:0048583	regulation of response to stimulus
1.35	1.03e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36	1.14e-04	GO:0048666	neuron development
1.34	1.40e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.27	1.55e-04	GO:0009892	negative regulation of metabolic process
1.29	1.58e-04	GO:0009891	positive regulation of biosynthetic process
1.72	2.02e-04	GO:0016055	Wnt receptor signaling pathway
1.28	2.36e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.34	2.46e-04	GO:0000902	cell morphogenesis
1.34	2.61e-04	GO:0009887	organ morphogenesis
1.33	3.07e-04	GO:0051726	regulation of cell cycle
1.29	3.34e-04	GO:0051128	regulation of cellular component organization
1.20	3.35e-04	GO:0006996	organelle organization
1.15	3.65e-04	GO:0048731	system development
1.20	3.77e-04	GO:0034645	cellular macromolecule biosynthetic process
1.17	4.38e-04	GO:0048869	cellular developmental process
1.29	5.00e-04	GO:0031399	regulation of protein modification process
1.41	5.40e-04	GO:0009968	negative regulation of signal transduction
1.32	5.89e-04	GO:0032989	cellular component morphogenesis
1.42	6.36e-04	GO:0048598	embryonic morphogenesis
1.17	7.92e-04	GO:0090304	nucleic acid metabolic process
1.36	7.92e-04	GO:0032990	cell part morphogenesis
1.37	8.10e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.32	9.23e-04	GO:0030030	cell projection organization
1.36	9.54e-04	GO:0000904	cell morphogenesis involved in differentiation
1.36	9.60e-04	GO:0007417	central nervous system development
1.48	1.01e-03	GO:0032446	protein modification by small protein conjugation
1.36	1.02e-03	GO:0048858	cell projection morphogenesis
1.40	1.05e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.42	1.20e-03	GO:0016568	chromatin modification
1.17	1.43e-03	GO:0030154	cell differentiation
1.21	1.44e-03	GO:0035556	intracellular signal transduction
1.19	1.83e-03	GO:0009059	macromolecule biosynthetic process
1.68	2.01e-03	GO:0030111	regulation of Wnt receptor signaling pathway
1.37	2.19e-03	GO:0048667	cell morphogenesis involved in neuron differentiation
1.17	2.71e-03	GO:0010467	gene expression
1.36	3.07e-03	GO:0048812	neuron projection morphogenesis
1.29	3.14e-03	GO:0019220	regulation of phosphate metabolic process
1.29	3.14e-03	GO:0051174	regulation of phosphorus metabolic process
1.24	3.29e-03	GO:0032774	RNA biosynthetic process
1.26	3.31e-03	GO:0044093	positive regulation of molecular function
1.36	3.49e-03	GO:0010648	negative regulation of cell communication
1.47	3.52e-03	GO:0016567	protein ubiquitination
1.25	3.77e-03	GO:0016265	death
1.39	3.91e-03	GO:0009792	embryo development ending in birth or egg hatching
1.12	4.26e-03	GO:0051179	localization
1.40	4.31e-03	GO:0007420	brain development
1.25	4.65e-03	GO:0008219	cell death
1.41	4.74e-03	GO:0070647	protein modification by small protein conjugation or removal
1.36	4.81e-03	GO:0023057	negative regulation of signaling
1.21	4.90e-03	GO:0051641	cellular localization
1.48	5.59e-03	GO:0003002	regionalization
1.11	5.61e-03	GO:0051716	cellular response to stimulus
1.29	5.70e-03	GO:0042325	regulation of phosphorylation
1.34	6.23e-03	GO:0072358	cardiovascular system development
1.34	6.23e-03	GO:0072359	circulatory system development
1.24	6.29e-03	GO:0048468	cell development
1.29	6.89e-03	GO:0001932	regulation of protein phosphorylation
1.37	8.05e-03	GO:0010627	regulation of intracellular protein kinase cascade
1.38	8.78e-03	GO:0043009	chordate embryonic development
1.36	8.96e-03	GO:0007409	axonogenesis
1.33	1.19e-02	GO:0031175	neuron projection development
1.55	1.26e-02	GO:0030900	forebrain development
1.59	1.27e-02	GO:0060562	epithelial tube morphogenesis
1.32	1.31e-02	GO:0051338	regulation of transferase activity
1.32	1.34e-02	GO:0043549	regulation of kinase activity
1.39	1.40e-02	GO:0007389	pattern specification process
1.43	1.46e-02	GO:0035295	tube development
1.33	1.55e-02	GO:0045859	regulation of protein kinase activity
1.12	1.55e-02	GO:0006810	transport
1.48	1.71e-02	GO:0045786	negative regulation of cell cycle
1.52	2.02e-02	GO:0035239	tube morphogenesis
3.11	2.03e-02	GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway
3.11	2.03e-02	GO:0090175	regulation of establishment of planar polarity
1.25	2.13e-02	GO:0046907	intracellular transport
1.12	2.13e-02	GO:0051234	establishment of localization
1.21	2.69e-02	GO:0043067	regulation of programmed cell death
1.58	2.70e-02	GO:0051099	positive regulation of binding
1.37	4.04e-02	GO:0071495	cellular response to endogenous stimulus
1.21	4.06e-02	GO:0010941	regulation of cell death
1.39	4.07e-02	GO:0032870	cellular response to hormone stimulus
1.25	4.40e-02	GO:0006915	apoptosis
1.29	4.43e-02	GO:0044265	cellular macromolecule catabolic process
1.33	4.47e-02	GO:0007243	intracellular protein kinase cascade
1.33	4.47e-02	GO:0023014	signal transduction via phosphorylation event
1.31	4.73e-02	GO:0048646	anatomical structure formation involved in morphogenesis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.13	7.93e-46	GO:0044424	intracellular part
1.12	7.65e-45	GO:0005622	intracellular
1.15	3.18e-32	GO:0043227	membrane-bounded organelle
1.14	7.50e-32	GO:0043231	intracellular membrane-bounded organelle
1.13	1.12e-30	GO:0043226	organelle
1.13	2.43e-30	GO:0043229	intracellular organelle
1.15	6.93e-30	GO:0005737	cytoplasm
1.17	3.68e-20	GO:0005634	nucleus
1.15	5.11e-16	GO:0044444	cytoplasmic part
1.25	8.75e-13	GO:0044428	nuclear part
1.14	6.36e-12	GO:0044446	intracellular organelle part
1.13	1.47e-11	GO:0044422	organelle part
1.25	5.61e-10	GO:0031981	nuclear lumen
1.04	6.19e-10	GO:0044464	cell part
1.04	6.88e-10	GO:0005623	cell
1.21	5.72e-09	GO:0070013	intracellular organelle lumen
1.20	1.52e-08	GO:0031974	membrane-enclosed lumen
1.20	2.70e-08	GO:0043233	organelle lumen
1.21	6.53e-08	GO:0005829	cytosol
1.24	8.99e-08	GO:0012505	endomembrane system
1.25	6.55e-07	GO:0005654	nucleoplasm
1.29	1.16e-06	GO:0005794	Golgi apparatus
1.17	8.48e-05	GO:0031090	organelle membrane
1.28	5.81e-04	GO:0044451	nucleoplasm part
1.13	1.12e-03	GO:0043234	protein complex
1.30	1.18e-03	GO:0044431	Golgi apparatus part
1.32	3.02e-03	GO:0000139	Golgi membrane
1.10	9.94e-03	GO:0032991	macromolecular complex
1.79	1.49e-02	GO:0030427	site of polarized growth
1.20	4.14e-02	GO:0042995	cell projection
1.75	4.81e-02	GO:0030426	growth cone
1.50	4.96e-02	GO:0000151	ubiquitin ligase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.17	2.57e-31	GO:0005515	protein binding
1.09	3.73e-27	GO:0005488	binding
1.21	1.69e-09	GO:0000166	nucleotide binding
1.35	6.40e-08	GO:0016301	kinase activity
1.22	1.21e-07	GO:0017076	purine nucleotide binding
1.21	2.78e-07	GO:0032553	ribonucleotide binding
1.21	2.78e-07	GO:0032555	purine ribonucleotide binding
1.55	4.64e-07	GO:0008134	transcription factor binding
1.21	5.06e-07	GO:0035639	purine ribonucleoside triphosphate binding
1.35	7.56e-07	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.30	3.30e-06	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.33	3.83e-06	GO:0019899	enzyme binding
1.36	4.96e-06	GO:0004672	protein kinase activity
1.22	7.36e-06	GO:0030554	adenyl nucleotide binding
1.49	7.59e-06	GO:0016563	transcription activator activity
1.41	1.39e-05	GO:0019904	protein domain specific binding
1.21	1.52e-05	GO:0032559	adenyl ribonucleotide binding
1.14	1.72e-05	GO:0003676	nucleic acid binding
1.21	3.16e-05	GO:0005524	ATP binding
1.19	4.71e-05	GO:0016740	transferase activity
1.40	5.67e-05	GO:0004674	protein serine/threonine kinase activity
1.16	5.85e-05	GO:0003677	DNA binding
1.26	6.96e-05	GO:0001071	nucleic acid binding transcription factor activity
1.26	6.96e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
1.09	2.26e-04	GO:0003824	catalytic activity
1.55	3.13e-04	GO:0010843	promoter binding
1.24	3.41e-04	GO:0030528	transcription regulator activity
1.44	3.47e-04	GO:0016564	transcription repressor activity
1.52	7.89e-04	GO:0000975	regulatory region DNA binding
1.52	7.89e-04	GO:0001067	regulatory region nucleic acid binding
1.52	7.89e-04	GO:0044212	transcription regulatory region DNA binding
1.45	6.42e-03	GO:0019787	small conjugating protein ligase activity
1.39	7.17e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.24	9.90e-03	GO:0042802	identical protein binding
1.41	1.18e-02	GO:0016881	acid-amino acid ligase activity
1.14	1.63e-02	GO:0008270	zinc ion binding
1.43	2.13e-02	GO:0004842	ubiquitin-protein ligase activity
1.32	3.15e-02	GO:0003712	transcription cofactor activity
1.40	3.57e-02	GO:0016791	phosphatase activity
1.50	3.60e-02	GO:0004721	phosphoprotein phosphatase activity
1.32	3.74e-02	GO:0000988	protein binding transcription factor activity
1.32	3.74e-02	GO:0000989	transcription factor binding transcription factor activity
1.24	4.00e-02	GO:0043565	sequence-specific DNA binding