Motif ID: TFDP1.p2

Z-value: 3.785


Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFDP1chr13_+_1142390470.137.5e-01Click!


Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2


Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_92920592 2.737 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr16_+_12995454 2.319 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr6_+_34205029 1.930 HMGA1
high mobility group AT-hook 1
chr3_+_110790460 1.792 NM_001243286
NM_015480
PVRL3

poliovirus receptor-related 3

chr2_-_225907312 1.596 NM_014689
DOCK10
dedicator of cytokinesis 10
chrX_+_30671456 1.486 NM_000167
NM_001128127
NM_001205019
NM_203391
GK



glycerol kinase



chr15_+_41786055 1.454 NM_002220
ITPKA
inositol-trisphosphate 3-kinase A
chr15_-_48937068 1.423 FBN1
fibrillin 1
chrX_+_30671602 1.399 GK
glycerol kinase
chr6_+_34204928 1.355 HMGA1
high mobility group AT-hook 1
chrX_+_30671537 1.340 GK
glycerol kinase
chr20_-_32274070 1.295 E2F1
E2F transcription factor 1
chr5_+_176560627 1.279 NM_022455
NSD1
nuclear receptor binding SET domain protein 1
chr19_+_14544100 1.238 NM_002741
PKN1
protein kinase N1
chr19_+_14544216 1.218 PKN1
protein kinase N1
chr11_-_19263144 1.208 E2F8
E2F transcription factor 8
chr15_-_75743776 1.172 NM_015477
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr20_-_32274154 1.158 NM_005225
E2F1
E2F transcription factor 1
chr14_+_29236882 1.128 FOXG1
forkhead box G1
chr1_-_212003576 1.068 LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr13_-_110438896 1.060 NM_003749
IRS2
insulin receptor substrate 2
chr15_+_33010174 1.053 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chrX_-_19140581 1.029 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr4_+_145567147 1.023 NM_022475
HHIP
hedgehog interacting protein
chr2_-_230579198 1.006 NM_139072
DNER
delta/notch-like EGF repeat containing
chr5_+_154134853 0.983 LARP1
La ribonucleoprotein domain family, member 1
chr15_+_99645152 0.956 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr6_+_160148485 0.955 WTAP
Wilms tumor 1 associated protein
chr22_+_29279573 0.940 NM_001206998
ZNRF3
zinc and ring finger 3
chr9_-_110251754 0.919 KLF4
Kruppel-like factor 4 (gut)
chr10_-_79397290 0.914 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_-_9439122 0.875 LOC440944
uncharacterized LOC440944
chr4_+_129732427 0.868 PHF17
PHD finger protein 17
chr15_-_75744029 0.864 NM_001145358
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr16_+_53164784 0.857 CHD9
chromodomain helicase DNA binding protein 9
chr20_-_3766905 0.854 NM_001810
CENPB
centromere protein B, 80kDa
chr6_+_34204690 0.850 HMGA1
high mobility group AT-hook 1
chr2_-_215674292 0.849 NM_000465
BARD1
BRCA1 associated RING domain 1
chr13_-_80915041 0.847 NM_005842
SPRY2
sprouty homolog 2 (Drosophila)
chr22_-_31741761 0.830 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr16_+_838645 0.828 CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr20_-_56284945 0.813 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr5_+_172068188 0.809 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr8_+_38644721 0.808 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr1_+_38259458 0.790 NM_001031740
NM_001113482
MANEAL

mannosidase, endo-alpha-like

chr3_-_136471186 0.788 NM_005862
STAG1
stromal antigen 1
chr20_+_42086533 0.774 SRSF6
serine/arginine-rich splicing factor 6
chr7_-_148581379 0.772 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr6_+_34205369 0.766 HMGA1
high mobility group AT-hook 1
chr5_-_131132642 0.765 FNIP1
folliculin interacting protein 1
chr5_+_138089073 0.764 NM_001903
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr9_+_131314669 0.758 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr20_+_59827452 0.744 NM_001794
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr5_+_148520985 0.741 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chr8_+_38644754 0.740 TACC1
transforming, acidic coiled-coil containing protein 1
chr6_-_52441815 0.738 NM_012288
TRAM2
translocation associated membrane protein 2
chr7_-_50861114 0.737 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr7_-_131241321 0.734 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr10_-_129924467 0.725 NM_001145966
NM_002417
MKI67

antigen identified by monoclonal antibody Ki-67

chr19_-_48673559 0.724 NM_000234
LIG1
ligase I, DNA, ATP-dependent
chr12_-_96184346 0.720 NTN4
netrin 4
chr7_+_116312412 0.713 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr12_-_120554453 0.713 RAB35
RAB35, member RAS oncogene family
chr2_-_99347430 0.712 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr16_-_73092533 0.711 NM_001164766
ZFHX3
zinc finger homeobox 3
chr11_+_118307072 0.707 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr22_-_36783851 0.698 MYH9
myosin, heavy chain 9, non-muscle
chr1_-_53793743 0.696 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr1_+_4715104 0.693 NM_001042478
NM_018836
AJAP1

adherens junctions associated protein 1

chr19_-_31840118 0.689 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr17_-_42907606 0.687 NM_005497
GJC1
gap junction protein, gamma 1, 45kDa
chr3_-_45267620 0.685 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr20_-_4982133 0.684 NM_005116
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr17_+_34900736 0.682 NM_024835
GGNBP2
gametogenetin binding protein 2
chr10_-_79397394 0.678 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr6_-_79787784 0.677 PHIP
pleckstrin homology domain interacting protein
chr19_-_56632600 0.676 ZNF787
zinc finger protein 787
chr11_+_35639734 0.675 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr1_+_9352955 0.675 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr11_-_19262424 0.672 NM_024680
E2F8
E2F transcription factor 8
chr7_+_138145179 0.670 TRIM24
tripartite motif containing 24
chr7_+_138144847 0.668 NM_003852
NM_015905
TRIM24

tripartite motif containing 24

chr16_+_838610 0.663 NM_022092
CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr6_-_86352656 0.662 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr7_-_148581377 0.662 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr5_+_176560882 0.653 NSD1
nuclear receptor binding SET domain protein 1
chr15_-_50978726 0.646 TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr7_-_148581359 0.643 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr5_-_131132709 0.637 FNIP1
folliculin interacting protein 1
chr2_-_167232464 0.628 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr22_-_36784001 0.628 MYH9
myosin, heavy chain 9, non-muscle
chr6_+_34204647 0.627 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr6_+_34204576 0.625 NM_002131
NM_145899
NM_145903
HMGA1


high mobility group AT-hook 1


chr8_-_145050896 0.625 NM_000445
PLEC
plectin
chr6_-_52441714 0.624 TRAM2
translocation associated membrane protein 2
chr16_-_1968230 0.623 NM_001009606
HS3ST6
heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr17_-_80056033 0.622 FASN
fatty acid synthase
chr17_-_17726855 0.622 SREBF1
sterol regulatory element binding transcription factor 1
chr18_+_2655885 0.617 NM_015295
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr8_-_12990731 0.615 NM_006094
DLC1
deleted in liver cancer 1
chr14_-_30396811 0.615 NM_002742
PRKD1
protein kinase D1
chr14_+_101193313 0.614 DLK1
delta-like 1 homolog (Drosophila)
chr1_+_229761988 0.613 URB2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr20_-_62601140 0.613 NM_020713
ZNF512B
zinc finger protein 512B
chr5_+_153570270 0.611 NM_198321
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr9_-_110251308 0.611 KLF4
Kruppel-like factor 4 (gut)
chr1_+_39875175 0.610 NM_015038
KIAA0754
KIAA0754
chr17_+_45727558 0.609 KPNB1
karyopherin (importin) beta 1
chr12_-_96793797 0.606 CDK17
cyclin-dependent kinase 17
chr1_+_183605207 0.605 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr1_+_25757381 0.601 NM_018202
TMEM57
transmembrane protein 57
chr1_+_27022521 0.601 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr7_-_50860665 0.597 GRB10
growth factor receptor-bound protein 10
chr6_+_31126114 0.597 NM_001077511
NM_007109
TCF19

transcription factor 19

chr1_-_245027210 0.596 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr12_-_120554551 0.593 RAB35
RAB35, member RAS oncogene family
chr7_+_7222142 0.591 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr7_+_90893735 0.591 NM_003505
FZD1
frizzled family receptor 1
chr13_+_33160610 0.589 PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr8_+_144816287 0.588 LOC100128338
uncharacterized LOC100128338
chr2_+_103236147 0.588 NM_003048
SLC9A2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr3_-_47823343 0.588 SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr9_-_86153048 0.587 NM_001244959
NM_174938
FRMD3

FERM domain containing 3

chr6_-_86352650 0.586 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr8_-_38325524 0.585 FGFR1
fibroblast growth factor receptor 1
chr14_+_65879439 0.583 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr13_-_107187312 0.579 NM_004093
EFNB2
ephrin-B2
chr22_+_38142245 0.578 TRIOBP
TRIO and F-actin binding protein
chr14_+_29236171 0.578 NM_005249
FOXG1
forkhead box G1
chr7_-_148581297 0.577 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr3_+_49507470 0.576 NM_001165928
NM_001177634
NM_001177635
NM_001177636
NM_001177637
NM_001177638
NM_001177639
NM_001177640
NM_001177641
NM_001177642
NM_001177644
NM_004393
DAG1











dystroglycan 1 (dystrophin-associated glycoprotein 1)











chr11_-_62314291 0.570 NM_001620
NM_024060
AHNAK

AHNAK nucleoprotein

chr17_-_80056104 0.566 NM_004104
FASN
fatty acid synthase
chr19_-_7293876 0.564 NM_000208
NM_001079817
INSR

insulin receptor

chr6_-_79787887 0.559 PHIP
pleckstrin homology domain interacting protein
chr7_-_148581403 0.557 NM_001203247
NM_001203248
NM_004456
NM_152998
EZH2



enhancer of zeste homolog 2 (Drosophila)



chr14_+_65879694 0.556 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr1_-_245027610 0.553 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr17_+_81037504 0.551 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr20_-_44718517 0.549 NCOA5
nuclear receptor coactivator 5
chr17_+_14204326 0.548 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr14_+_101193275 0.548 DLK1
delta-like 1 homolog (Drosophila)
chr2_-_214016332 0.548 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr14_+_101193190 0.547 NM_003836
DLK1
delta-like 1 homolog (Drosophila)
chr11_+_12695851 0.546 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr16_-_73082169 0.545 NM_006885
ZFHX3
zinc finger homeobox 3
chr7_+_129251579 0.544 NRF1
nuclear respiratory factor 1
chr9_-_113800243 0.539 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr16_+_838634 0.533 CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr12_+_51985016 0.531 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr3_-_167813058 0.531 GOLIM4
golgi integral membrane protein 4
chr1_-_92351476 0.531 TGFBR3
transforming growth factor, beta receptor III
chr18_-_65183922 0.531 NM_032160
DSEL
dermatan sulfate epimerase-like
chr7_-_23509631 0.530


chr3_-_127541160 0.530 NM_007283
MGLL
monoglyceride lipase
chr22_-_36783977 0.529 MYH9
myosin, heavy chain 9, non-muscle
chr6_+_34204663 0.529 HMGA1
high mobility group AT-hook 1
chr1_+_9648931 0.528 NM_001010866
NM_001130924
TMEM201

transmembrane protein 201

chr22_+_31090792 0.528 NM_030758
OSBP2
oxysterol binding protein 2
chrX_-_150067127 0.524 NM_001184808
NM_001242614
NM_031462
NM_134445
NM_134446
CD99L2




CD99 molecule-like 2




chr1_-_20812271 0.522 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr16_-_17564737 0.521 NM_022166
XYLT1
xylosyltransferase I
chr2_+_79740171 0.520 CTNNA2
catenin (cadherin-associated protein), alpha 2
chr5_+_138089118 0.518 CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr9_+_37650996 0.518 NM_014907
FRMPD1
FERM and PDZ domain containing 1
chr3_+_57994087 0.516 NM_001164317
NM_001164318
NM_001164319
NM_001457
FLNB



filamin B, beta



chr7_-_132261228 0.516 PLXNA4
plexin A4
chr4_-_83350829 0.515 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr3_-_45267804 0.514 NM_015444
TMEM158
transmembrane protein 158 (gene/pseudogene)
chr3_-_52719514 0.512 NM_018313
PBRM1
polybromo 1
chr6_+_7108864 0.512 RREB1
ras responsive element binding protein 1
chr16_-_3030473 0.510 NM_004203
NM_182687
PKMYT1

protein kinase, membrane associated tyrosine/threonine 1

chr7_+_150756753 0.508 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr6_-_86352696 0.504 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr12_+_98909405 0.504 TMPO
thymopoietin
chr4_+_140222668 0.503 NM_057175
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr1_+_114472438 0.501 HIPK1
homeodomain interacting protein kinase 1
chr6_+_42750465 0.499 FLJ38717
FLJ38717 protein
chr2_-_61697846 0.498 NM_014709
USP34
ubiquitin specific peptidase 34
chr12_-_122907083 0.498 NM_001247997
NM_002956
NM_198240
CLIP1


CAP-GLY domain containing linker protein 1


chr20_-_60942300 0.497 NM_005560
LAMA5
laminin, alpha 5
chr1_-_227505796 0.495 NM_003607
NM_014826
CDC42BPA

CDC42 binding protein kinase alpha (DMPK-like)

chr10_+_92980322 0.492 NM_032373
PCGF5
polycomb group ring finger 5
chr6_+_31126340 0.489 TCF19
transcription factor 19
chr1_+_23037329 0.489 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr8_-_144241456 0.487 NM_002347
LY6H
lymphocyte antigen 6 complex, locus H
chr17_-_42296923 0.486 UBTF
upstream binding transcription factor, RNA polymerase I
chr8_+_81398416 0.485 NM_001105539
NM_023929
ZBTB10

zinc finger and BTB domain containing 10

chr10_-_15413054 0.484 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr18_-_25756946 0.483 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr3_-_47620186 0.482 NM_001206943
NM_001206944
NM_006574
CSPG5


chondroitin sulfate proteoglycan 5 (neuroglycan C)


chr5_-_114632240 0.481 NM_001040440
CCDC112
coiled-coil domain containing 112
chr2_-_61697899 0.480 USP34
ubiquitin specific peptidase 34
chr12_-_131323616 0.479 NM_001980
NM_194356
STX2

syntaxin 2

chr6_-_153304590 0.477 NM_001142522
FBXO5
F-box protein 5
chr18_-_25757351 0.477 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr17_+_47074749 0.477 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr1_+_90098693 0.474 LRRC8C
leucine rich repeat containing 8 family, member C
chr5_-_131132690 0.473 FNIP1
folliculin interacting protein 1
chr2_-_174828775 0.472 NM_001017371
SP3
Sp3 transcription factor

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.12 1.27e-45 GO:0009987 cellular process
1.20 8.29e-35 GO:0044237 cellular metabolic process
1.25 1.15e-34 GO:0044260 cellular macromolecule metabolic process
1.30 5.78e-25 GO:0071842 cellular component organization at cellular level
1.25 8.75e-25 GO:0016043 cellular component organization
1.28 1.01e-23 GO:0071841 cellular component organization or biogenesis at cellular level
1.24 1.33e-23 GO:0071840 cellular component organization or biogenesis
1.16 1.41e-23 GO:0044238 primary metabolic process
1.19 1.28e-22 GO:0043170 macromolecule metabolic process
1.37 3.36e-22 GO:0006996 organelle organization
1.27 1.13e-21 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 1.90e-21 GO:0008152 metabolic process
1.23 1.90e-19 GO:0006807 nitrogen compound metabolic process
1.23 4.11e-19 GO:0034641 cellular nitrogen compound metabolic process
1.27 4.58e-19 GO:0044267 cellular protein metabolic process
1.33 2.46e-18 GO:0009059 macromolecule biosynthetic process
1.33 6.25e-18 GO:0034645 cellular macromolecule biosynthetic process
1.27 7.09e-18 GO:0044249 cellular biosynthetic process
1.26 1.33e-17 GO:0009058 biosynthetic process
1.13 3.27e-17 GO:0050794 regulation of cellular process
1.30 7.95e-17 GO:0006464 protein modification process
1.41 9.85e-17 GO:0007049 cell cycle
1.27 3.46e-16 GO:0090304 nucleic acid metabolic process
1.12 4.31e-15 GO:0050789 regulation of biological process
1.20 6.34e-15 GO:0080090 regulation of primary metabolic process
1.19 1.12e-14 GO:0031323 regulation of cellular metabolic process
1.28 1.56e-14 GO:0043412 macromolecule modification
1.51 1.62e-14 GO:0051276 chromosome organization
1.10 4.06e-13 GO:0065007 biological regulation
1.17 6.41e-13 GO:0019222 regulation of metabolic process
1.32 7.84e-13 GO:0033036 macromolecule localization
1.19 1.18e-12 GO:0060255 regulation of macromolecule metabolic process
1.36 1.48e-12 GO:0008104 protein localization
1.32 3.07e-12 GO:0051641 cellular localization
1.40 2.12e-11 GO:0046907 intracellular transport
1.29 2.66e-11 GO:0007399 nervous system development
1.26 2.74e-11 GO:0016070 RNA metabolic process
1.39 6.67e-11 GO:0022402 cell cycle process
1.42 6.79e-11 GO:0022403 cell cycle phase
1.46 1.08e-10 GO:0000278 mitotic cell cycle
1.21 2.11e-10 GO:0048522 positive regulation of cellular process
1.22 3.15e-10 GO:0048523 negative regulation of cellular process
1.36 3.16e-10 GO:0045184 establishment of protein localization
1.56 5.87e-10 GO:0016568 chromatin modification
1.21 1.04e-09 GO:0048519 negative regulation of biological process
1.19 2.13e-09 GO:0051171 regulation of nitrogen compound metabolic process
1.48 2.27e-09 GO:0006325 chromatin organization
1.19 2.42e-09 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 3.28e-09 GO:0015031 protein transport
1.18 3.38e-09 GO:0019538 protein metabolic process
1.23 4.64e-09 GO:0010467 gene expression
1.25 4.73e-09 GO:0023051 regulation of signaling
1.32 8.61e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.33 9.19e-09 GO:0022008 neurogenesis
1.35 1.50e-08 GO:0033554 cellular response to stress
1.32 1.71e-08 GO:0032774 RNA biosynthetic process
1.15 2.26e-08 GO:0032502 developmental process
1.29 2.87e-08 GO:0051649 establishment of localization in cell
1.26 3.23e-08 GO:0009966 regulation of signal transduction
1.43 4.49e-08 GO:0070727 cellular macromolecule localization
1.18 5.37e-08 GO:0048518 positive regulation of biological process
1.26 6.26e-08 GO:0035556 intracellular signal transduction
1.32 6.92e-08 GO:0010605 negative regulation of macromolecule metabolic process
1.43 7.20e-08 GO:0034613 cellular protein localization
1.30 8.98e-08 GO:0009892 negative regulation of metabolic process
1.31 2.21e-07 GO:0031324 negative regulation of cellular metabolic process
1.18 2.25e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.18 2.40e-07 GO:0010468 regulation of gene expression
1.15 2.53e-07 GO:0051179 localization
1.16 2.73e-07 GO:0048856 anatomical structure development
1.37 4.19e-07 GO:0051726 regulation of cell cycle
1.31 5.06e-07 GO:0048699 generation of neurons
1.31 6.25e-07 GO:0006351 transcription, DNA-dependent
1.28 1.25e-06 GO:0032268 regulation of cellular protein metabolic process
1.18 1.37e-06 GO:0051252 regulation of RNA metabolic process
1.48 1.37e-06 GO:0051301 cell division
1.16 1.65e-06 GO:0009889 regulation of biosynthetic process
1.16 2.12e-06 GO:0031326 regulation of cellular biosynthetic process
1.25 2.12e-06 GO:0009893 positive regulation of metabolic process
1.17 2.47e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.48 2.50e-06 GO:0018193 peptidyl-amino acid modification
1.59 2.68e-06 GO:0048011 nerve growth factor receptor signaling pathway
1.51 3.29e-06 GO:0051325 interphase
1.25 3.62e-06 GO:0031325 positive regulation of cellular metabolic process
1.26 4.39e-06 GO:0051246 regulation of protein metabolic process
1.14 6.04e-06 GO:0007275 multicellular organismal development
1.25 8.88e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.15 1.14e-05 GO:0048731 system development
1.15 1.20e-05 GO:0051234 establishment of localization
1.49 1.27e-05 GO:0051329 interphase of mitotic cell cycle
1.30 1.35e-05 GO:0031399 regulation of protein modification process
1.32 1.62e-05 GO:0009890 negative regulation of biosynthetic process
1.34 1.64e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.21 2.65e-05 GO:0065009 regulation of molecular function
1.62 3.38e-05 GO:0016569 covalent chromatin modification
1.35 3.86e-05 GO:0048666 neuron development
1.12 4.19e-05 GO:0051716 cellular response to stimulus
1.39 5.06e-05 GO:0000279 M phase
1.32 5.94e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.61 5.98e-05 GO:0016570 histone modification
1.33 5.98e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31 6.91e-05 GO:0030182 neuron differentiation
1.60 6.98e-05 GO:0006260 DNA replication
1.31 9.97e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.46 1.06e-04 GO:0000087 M phase of mitotic cell cycle
1.40 1.27e-04 GO:0006886 intracellular protein transport
1.27 1.33e-04 GO:0043933 macromolecular complex subunit organization
1.46 1.42e-04 GO:0048285 organelle fission
1.32 1.49e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.40 1.55e-04 GO:0007264 small GTPase mediated signal transduction
1.14 1.56e-04 GO:0006810 transport
1.46 1.56e-04 GO:0000280 nuclear division
1.46 1.56e-04 GO:0007067 mitosis
1.35 1.63e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.36 1.83e-04 GO:0031175 neuron projection development
1.42 1.86e-04 GO:0010564 regulation of cell cycle process
1.32 1.91e-04 GO:0000902 cell morphogenesis
1.16 1.92e-04 GO:0048869 cellular developmental process
1.23 1.97e-04 GO:0044248 cellular catabolic process
1.24 2.14e-04 GO:0006793 phosphorus metabolic process
1.24 2.14e-04 GO:0006796 phosphate metabolic process
1.28 2.26e-04 GO:0016192 vesicle-mediated transport
1.31 2.27e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.34 2.28e-04 GO:0006974 response to DNA damage stimulus
1.16 2.85e-04 GO:0006355 regulation of transcription, DNA-dependent
1.31 2.98e-04 GO:0030030 cell projection organization
1.16 3.18e-04 GO:0030154 cell differentiation
1.35 3.20e-04 GO:0000904 cell morphogenesis involved in differentiation
1.27 4.09e-04 GO:0051128 regulation of cellular component organization
1.25 4.49e-04 GO:0048468 cell development
1.19 4.56e-04 GO:0009653 anatomical structure morphogenesis
1.26 5.05e-04 GO:0016265 death
1.27 5.64e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.29 5.70e-04 GO:0019220 regulation of phosphate metabolic process
1.29 5.70e-04 GO:0051174 regulation of phosphorus metabolic process
1.25 5.99e-04 GO:0008219 cell death
1.33 6.08e-04 GO:0016071 mRNA metabolic process
1.47 6.75e-04 GO:0016567 protein ubiquitination
1.29 6.89e-04 GO:0051254 positive regulation of RNA metabolic process
1.11 7.28e-04 GO:0023052 signaling
1.27 7.53e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.23 8.15e-04 GO:0022607 cellular component assembly
1.66 8.90e-04 GO:0006403 RNA localization
1.28 1.03e-03 GO:0006915 apoptosis
1.28 1.07e-03 GO:0045595 regulation of cell differentiation
1.29 1.09e-03 GO:0032989 cellular component morphogenesis
1.27 1.55e-03 GO:0012501 programmed cell death
1.27 1.91e-03 GO:0065003 macromolecular complex assembly
1.43 2.08e-03 GO:0032446 protein modification by small protein conjugation
1.64 2.68e-03 GO:0050657 nucleic acid transport
1.64 2.68e-03 GO:0050658 RNA transport
1.64 2.68e-03 GO:0051236 establishment of RNA localization
1.27 3.03e-03 GO:0042325 regulation of phosphorylation
1.20 3.23e-03 GO:0044085 cellular component biogenesis
1.23 3.33e-03 GO:0050793 regulation of developmental process
1.39 3.43e-03 GO:0019941 modification-dependent protein catabolic process
1.28 3.45e-03 GO:0001932 regulation of protein phosphorylation
1.60 3.80e-03 GO:0048193 Golgi vesicle transport
1.38 4.16e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
1.39 4.60e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.28 5.49e-03 GO:0071822 protein complex subunit organization
1.38 5.57e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.24 5.62e-03 GO:0044093 positive regulation of molecular function
1.48 5.65e-03 GO:0009101 glycoprotein biosynthetic process
1.11 5.87e-03 GO:0007165 signal transduction
1.30 6.06e-03 GO:0051253 negative regulation of RNA metabolic process
1.30 6.62e-03 GO:0044265 cellular macromolecule catabolic process
1.38 6.69e-03 GO:0070647 protein modification by small protein conjugation or removal
1.20 6.96e-03 GO:0050790 regulation of catalytic activity
1.51 7.06e-03 GO:0051169 nuclear transport
1.43 7.47e-03 GO:0009100 glycoprotein metabolic process
1.31 7.75e-03 GO:0034621 cellular macromolecular complex subunit organization
1.51 7.76e-03 GO:0006913 nucleocytoplasmic transport
1.63 7.93e-03 GO:0007265 Ras protein signal transduction
1.41 8.07e-03 GO:0010608 posttranscriptional regulation of gene expression
1.64 1.00e-02 GO:0051028 mRNA transport
2.01 1.05e-02 GO:0045767 regulation of anti-apoptosis
1.56 1.10e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.27 1.26e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.27 1.40e-02 GO:0010629 negative regulation of gene expression
1.29 1.49e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.30 1.50e-02 GO:0032990 cell part morphogenesis
1.35 1.50e-02 GO:0007420 brain development
1.25 1.57e-02 GO:0010628 positive regulation of gene expression
1.36 1.67e-02 GO:0044257 cellular protein catabolic process
1.27 1.69e-02 GO:0006259 DNA metabolic process
1.31 1.72e-02 GO:0048812 neuron projection morphogenesis
1.30 1.79e-02 GO:0043549 regulation of kinase activity
1.29 1.79e-02 GO:0048858 cell projection morphogenesis
1.76 1.88e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.29 2.15e-02 GO:0051338 regulation of transferase activity
1.32 2.20e-02 GO:0007409 axonogenesis
1.20 2.37e-02 GO:0010646 regulation of cell communication
1.50 2.40e-02 GO:0070085 glycosylation
1.30 2.56e-02 GO:0045859 regulation of protein kinase activity
2.06 3.43e-02 GO:0045768 positive regulation of anti-apoptosis
1.49 3.63e-02 GO:0006486 protein glycosylation
1.49 3.63e-02 GO:0043413 macromolecule glycosylation
1.19 3.65e-02 GO:0010941 regulation of cell death
1.76 3.67e-02 GO:0006473 protein acetylation
1.22 3.73e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.22 3.77e-02 GO:0009891 positive regulation of biosynthetic process
1.20 3.96e-02 GO:0032879 regulation of localization
1.43 3.98e-02 GO:0033365 protein localization to organelle
1.23 4.38e-02 GO:0006468 protein phosphorylation
1.94 4.41e-02 GO:0000819 sister chromatid segregation
1.70 4.61e-02 GO:0018205 peptidyl-lysine modification
1.70 4.61e-02 GO:0043543 protein acylation
1.30 4.80e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.14 4.98e-02 GO:0048583 regulation of response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 8.75e-83 GO:0005622 intracellular
1.15 1.48e-82 GO:0044424 intracellular part
1.17 3.63e-64 GO:0043229 intracellular organelle
1.17 4.82e-64 GO:0043226 organelle
1.19 1.25e-63 GO:0043231 intracellular membrane-bounded organelle
1.19 1.37e-63 GO:0043227 membrane-bounded organelle
1.17 4.48e-47 GO:0005737 cytoplasm
1.23 5.28e-45 GO:0005634 nucleus
1.22 1.29e-40 GO:0044446 intracellular organelle part
1.22 5.14e-40 GO:0044422 organelle part
1.19 7.76e-33 GO:0044444 cytoplasmic part
1.35 1.55e-29 GO:0044428 nuclear part
1.05 2.18e-25 GO:0005623 cell
1.35 3.04e-25 GO:0031981 nuclear lumen
1.05 3.19e-25 GO:0044464 cell part
1.29 1.42e-21 GO:0070013 intracellular organelle lumen
1.30 3.00e-21 GO:0005829 cytosol
1.28 1.12e-20 GO:0031974 membrane-enclosed lumen
1.38 1.99e-20 GO:0005654 nucleoplasm
1.28 8.31e-20 GO:0043233 organelle lumen
1.29 3.50e-14 GO:0012505 endomembrane system
1.50 1.17e-13 GO:0005694 chromosome
1.52 2.32e-12 GO:0044427 chromosomal part
1.20 9.13e-12 GO:0043228 non-membrane-bounded organelle
1.20 9.13e-12 GO:0043232 intracellular non-membrane-bounded organelle
1.23 1.01e-11 GO:0031090 organelle membrane
1.34 2.31e-11 GO:0005794 Golgi apparatus
1.16 6.49e-11 GO:0032991 macromolecular complex
1.17 7.28e-10 GO:0043234 protein complex
1.41 1.36e-09 GO:0044431 Golgi apparatus part
1.44 8.26e-09 GO:0000139 Golgi membrane
1.62 1.06e-07 GO:0000228 nuclear chromosome
1.33 5.89e-07 GO:0015630 microtubule cytoskeleton
1.32 9.65e-07 GO:0044451 nucleoplasm part
1.54 1.63e-06 GO:0005635 nuclear envelope
1.63 3.21e-06 GO:0044454 nuclear chromosome part
1.68 5.76e-06 GO:0031965 nuclear membrane
1.50 3.04e-05 GO:0000785 chromatin
1.79 6.38e-05 GO:0016585 chromatin remodeling complex
1.54 1.05e-04 GO:0031252 cell leading edge
1.27 1.30e-04 GO:0031975 envelope
1.27 1.44e-04 GO:0031967 organelle envelope
1.38 3.85e-04 GO:0005815 microtubule organizing center
1.50 1.06e-03 GO:0005819 spindle
1.51 1.12e-03 GO:0043025 neuronal cell body
1.44 1.23e-03 GO:0005813 centrosome
1.32 2.13e-03 GO:0043005 neuron projection
1.48 2.66e-03 GO:0044297 cell body
1.22 3.88e-03 GO:0031982 vesicle
1.19 3.97e-03 GO:0005783 endoplasmic reticulum
1.76 5.30e-03 GO:0034399 nuclear periphery
1.22 7.03e-03 GO:0031410 cytoplasmic vesicle
1.36 7.94e-03 GO:0005874 microtubule
1.51 9.05e-03 GO:0000775 chromosome, centromeric region
1.67 9.92e-03 GO:0000790 nuclear chromatin
1.32 1.13e-02 GO:0048471 perinuclear region of cytoplasm
2.40 1.21e-02 GO:0031519 PcG protein complex
1.28 1.29e-02 GO:0005768 endosome
1.50 1.52e-02 GO:0000793 condensed chromosome
1.75 1.85e-02 GO:0016363 nuclear matrix
1.26 1.97e-02 GO:0005730 nucleolus
1.22 2.79e-02 GO:0005789 endoplasmic reticulum membrane
1.19 2.87e-02 GO:0005626 insoluble fraction
2.11 3.28e-02 GO:0005637 nuclear inner membrane
1.20 3.30e-02 GO:0044432 endoplasmic reticulum part
1.20 4.34e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.20 4.34e-02 GO:0031988 membrane-bounded vesicle
1.37 4.83e-02 GO:0016604 nuclear body

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 8.09e-48 GO:0005515 protein binding
1.09 2.03e-34 GO:0005488 binding
1.24 6.64e-15 GO:0000166 nucleotide binding
1.18 1.46e-12 GO:0003676 nucleic acid binding
1.24 3.74e-10 GO:0016740 transferase activity
1.21 1.98e-08 GO:0035639 purine ribonucleoside triphosphate binding
1.33 2.01e-08 GO:0003723 RNA binding
1.21 3.90e-08 GO:0017076 purine nucleotide binding
1.21 5.84e-08 GO:0032553 ribonucleotide binding
1.21 5.84e-08 GO:0032555 purine ribonucleotide binding
1.11 2.27e-07 GO:0003824 catalytic activity
1.17 6.21e-07 GO:0003677 DNA binding
1.40 4.47e-06 GO:0019904 protein domain specific binding
1.27 8.12e-06 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.20 9.51e-06 GO:0030554 adenyl nucleotide binding
1.20 1.13e-05 GO:0005524 ATP binding
1.29 1.28e-05 GO:0019899 enzyme binding
1.20 1.79e-05 GO:0032559 adenyl ribonucleotide binding
1.26 2.08e-04 GO:0016301 kinase activity
1.23 2.16e-04 GO:0030528 transcription regulator activity
1.53 2.25e-04 GO:0003682 chromatin binding
1.26 4.51e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.43 5.97e-04 GO:0016881 acid-amino acid ligase activity
1.32 7.83e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.32 8.40e-04 GO:0030695 GTPase regulator activity
1.44 1.98e-03 GO:0019787 small conjugating protein ligase activity
1.32 2.11e-03 GO:0004674 protein serine/threonine kinase activity
1.39 2.26e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.27 2.95e-03 GO:0004672 protein kinase activity
1.24 4.06e-03 GO:0042802 identical protein binding
1.36 5.13e-03 GO:0016563 transcription activator activity
1.43 5.20e-03 GO:0004842 ubiquitin-protein ligase activity
1.30 6.75e-03 GO:0016874 ligase activity
1.40 8.01e-03 GO:0016791 phosphatase activity
1.50 8.36e-03 GO:0004721 phosphoprotein phosphatase activity
1.20 8.87e-03 GO:0030234 enzyme regulator activity
1.31 1.60e-02 GO:0000988 protein binding transcription factor activity
1.31 1.60e-02 GO:0000989 transcription factor binding transcription factor activity
1.31 2.13e-02 GO:0003712 transcription cofactor activity
1.19 2.39e-02 GO:0001071 nucleic acid binding transcription factor activity
1.19 2.39e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.41 3.44e-02 GO:0019901 protein kinase binding