Motif ID: TGIF1.p2

Z-value: 1.403


Transcription factors associated with TGIF1.p2:

Gene SymbolEntrez IDGene Name
TGIF1 7050 TGFB-induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TGIF1chr18_+_3447607-0.423.0e-01Click!


Activity profile for motif TGIF1.p2.

activity profile for motif TGIF1.p2


Sorted Z-values histogram for motif TGIF1.p2

Sorted Z-values for motif TGIF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TGIF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_33359607 3.217 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr1_+_163038564 2.573 NM_005613
RGS4
regulator of G-protein signaling 4
chr1_+_79086087 2.557 NM_006820
IFI44L
interferon-induced protein 44-like
chr5_-_19988293 2.538 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr1_+_163038395 2.531 NM_001102445
RGS4
regulator of G-protein signaling 4
chr3_+_45067750 2.482 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr15_-_48937795 2.072 NM_000138
FBN1
fibrillin 1
chr12_+_53442732 1.556 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr13_-_38172862 1.529 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr4_+_55095263 1.445 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr10_+_69869249 1.345 NM_032578
MYPN
myopalladin
chr6_+_73076431 1.255 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr4_-_175443791 1.204 NM_000860
NM_001145816
HPGD

hydroxyprostaglandin dehydrogenase 15-(NAD)

chr4_-_175443601 1.192 HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr17_-_53809444 1.107 NM_001099640
TMEM100
transmembrane protein 100
chr11_+_6411637 1.065 NM_000543
NM_001007593
SMPD1

sphingomyelin phosphodiesterase 1, acid lysosomal

chr17_-_66951381 1.032 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr1_+_163038934 1.019 NM_001113381
RGS4
regulator of G-protein signaling 4
chr11_-_119294242 1.001 NM_006288
THY1
Thy-1 cell surface antigen
chr9_-_95244634 0.973 ASPN
asporin
chr13_-_34250899 0.874 NM_001243476
STARD13
StAR-related lipid transfer (START) domain containing 13
chr8_-_93029864 0.807 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_-_95244750 0.785 NM_001193335
NM_017680
ASPN

asporin

chr16_+_2880172 0.779 NM_145252
ZG16B
zymogen granule protein 16 homolog B (rat)
chr1_-_208417635 0.772 NM_025179
PLXNA2
plexin A2
chr2_+_8822112 0.757 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr7_-_152132924 0.757 MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr4_-_185747051 0.732 ACSL1
acyl-CoA synthetase long-chain family member 1
chr1_+_178063631 0.705 RASAL2
RAS protein activator like 2
chr3_-_129325175 0.699 NM_015103
PLXND1
plexin D1
chr17_+_68165660 0.686 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr3_+_69788562 0.680 NM_198159
MITF
microphthalmia-associated transcription factor
chr1_-_241799101 0.679 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr19_+_39786964 0.674 NM_172140
IL29
interleukin 29 (interferon, lambda 1)
chr16_+_27413482 0.671 NM_181078
NM_181079
IL21R

interleukin 21 receptor

chr4_+_186990308 0.668 NM_003265
TLR3
toll-like receptor 3
chr13_-_33859835 0.659 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr7_-_141646716 0.645 NM_013252
CLEC5A
C-type lectin domain family 5, member A
chr6_+_72926462 0.640 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr5_-_127873734 0.639 NM_001999
FBN2
fibrillin 2
chrX_-_99987072 0.638 NM_001129896
SYTL4
synaptotagmin-like 4
chr20_+_33299315 0.634 TP53INP2
tumor protein p53 inducible nuclear protein 2
chr4_-_128886283 0.627 MFSD8
major facilitator superfamily domain containing 8
chr6_+_136172802 0.615 NM_018945
PDE7B
phosphodiesterase 7B
chr12_-_7281374 0.610 NM_031491
RBP5
retinol binding protein 5, cellular
chr5_+_71403040 0.608 NM_005909
MAP1B
microtubule-associated protein 1B
chr3_+_186560462 0.604 NM_001177800
NM_004797
ADIPOQ

adiponectin, C1Q and collagen domain containing

chr11_+_120973374 0.602 NM_005422
TECTA
tectorin alpha
chr13_+_96329398 0.601 DNAJC3
DnaJ (Hsp40) homolog, subfamily C, member 3
chr20_+_43029973 0.595 HNF4A
hepatocyte nuclear factor 4, alpha
chr9_+_34652125 0.595 NM_001142784
IL11RA
interleukin 11 receptor, alpha
chr12_+_108909049 0.589 NM_007076
FICD
FIC domain containing
chr1_+_6615337 0.588 NM_138697
NM_177540
TAS1R1

taste receptor, type 1, member 1

chr2_-_43903460 0.587 NM_001101330
LOC728819
hCG1645220
chr4_+_55095433 0.584 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr11_-_26743545 0.583 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr11_+_12132063 0.583 NM_014632
MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2
chr11_+_67776016 0.581 NM_001161473
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr16_+_2807490 0.572


chr5_+_140868721 0.568 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr11_+_19734821 0.561 NM_001244963
NM_145117
NM_182964
NAV2


neuron navigator 2


chrX_-_153775427 0.550 G6PD
glucose-6-phosphate dehydrogenase
chrX_+_9754465 0.545 NM_001649
SHROOM2
shroom family member 2
chr18_-_56296188 0.539 NM_052947
ALPK2
alpha-kinase 2
chr1_-_57045129 0.537 PPAP2B
phosphatidic acid phosphatase type 2B
chr3_+_186560478 0.535 ADIPOQ
adiponectin, C1Q and collagen domain containing
chrX_-_99986496 0.533 NM_001174068
NM_080737
SYTL4

synaptotagmin-like 4

chr5_-_78281556 0.520 ARSB
arylsulfatase B
chr1_-_57045235 0.517 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr1_+_226016428 0.513 EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr9_+_127420690 0.510 MIR181A2HG
MIR181A2 host gene (non-protein coding)
chr7_-_100493481 0.510 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr16_-_4896197 0.507 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr18_-_52626636 0.503 NM_025214
CCDC68
coiled-coil domain containing 68
chr14_-_73360792 0.502 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr4_-_156787377 0.500 NM_017419
ACCN5
amiloride-sensitive cation channel 5, intestinal
chr15_+_43809805 0.498 NM_002373
MAP1A
microtubule-associated protein 1A
chr20_+_33299779 0.498 TP53INP2
tumor protein p53 inducible nuclear protein 2
chr5_+_71502700 0.497 MAP1B
microtubule-associated protein 1B
chr8_-_93111915 0.496 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_-_52719514 0.495 NM_018313
PBRM1
polybromo 1
chr18_+_66465316 0.487 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr4_+_114214102 0.484 ANK2
ankyrin 2, neuronal
chr6_+_31623688 0.481 APOM
apolipoprotein M
chr5_-_146833150 0.476 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr1_+_39875175 0.474 NM_015038
KIAA0754
KIAA0754
chr17_+_3377346 0.459 NM_001128085
ASPA
aspartoacylase
chr6_+_31623668 0.456 NM_019101
APOM
apolipoprotein M
chr7_-_19157262 0.452 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr6_-_58287651 0.449 GUSBP4
glucuronidase, beta pseudogene 4
chr5_-_78281076 0.448 ARSB
arylsulfatase B
chr16_-_12897693 0.447 NM_001099455
NM_018340
CPPED1

calcineurin-like phosphoesterase domain containing 1

chr12_-_91572328 0.447 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chr3_-_187871816 0.446 LPP-AS2
LPP antisense RNA 2 (non-protein coding)
chrX_-_48931645 0.443 NM_007213
PRAF2
PRA1 domain family, member 2
chr7_+_95401817 0.438 NM_001135556
NM_001135557
NM_004411
DYNC1I1


dynein, cytoplasmic 1, intermediate chain 1


chr17_+_74734106 0.438 MFSD11
major facilitator superfamily domain containing 11
chr12_+_55248298 0.435 NM_058173
MUCL1
mucin-like 1
chr1_-_57045214 0.432 PPAP2B
phosphatidic acid phosphatase type 2B
chr4_+_113739203 0.430 NM_001127493
ANK2
ankyrin 2, neuronal
chr8_-_108510094 0.424 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr5_-_154230157 0.421 C5orf4
chromosome 5 open reading frame 4
chr3_-_3221385 0.419 CRBN
cereblon
chr3_-_127541975 0.417 NM_001003794
MGLL
monoglyceride lipase
chr1_+_179965756 0.416 CEP350
centrosomal protein 350kDa
chr7_-_80141241 0.413 NM_001102386
GNAT3
guanine nucleotide binding protein, alpha transducing 3
chr10_+_90639900 0.409 NM_020799
STAMBPL1
STAM binding protein-like 1
chr2_-_202563353 0.406 NM_033066
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr2_-_211179765 0.405 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr17_-_15168590 0.405 NM_000304
PMP22
peripheral myelin protein 22
chr5_+_180257979 0.402 LOC729678
uncharacterized LOC729678
chr1_-_145039631 0.400 NM_001198832
PDE4DIP
phosphodiesterase 4D interacting protein
chr10_-_14372807 0.400 NM_018027
FRMD4A
FERM domain containing 4A
chr7_-_152133071 0.399 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr21_+_47531369 0.398 COL6A2
collagen, type VI, alpha 2
chr8_+_28174648 0.395 NM_006228
PNOC
prepronociceptin
chrX_-_103087106 0.395 NM_016370
RAB9B
RAB9B, member RAS oncogene family
chr16_-_67217825 0.395 NM_001040715
KIAA0895L
KIAA0895-like
chr3_-_3221390 0.391 NM_001173482
NM_016302
CRBN

cereblon

chr7_+_120590816 0.388 NM_019071
NM_198267
ING3

inhibitor of growth family, member 3

chr17_-_72542148 0.387 CD300C
CD300c molecule
chr10_+_124768401 0.386 NM_001609
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chr8_-_42065037 0.384 PLAT
plasminogen activator, tissue
chr1_-_155532152 0.382 ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr22_-_36013303 0.381 NM_005368
NM_203378
MB

myoglobin

chr3_-_3221361 0.376 CRBN
cereblon
chr9_+_18474078 0.374 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr15_-_70994608 0.372 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr8_+_37654395 0.370 NM_032777
GPR124
G protein-coupled receptor 124
chr15_-_43559054 0.367 NM_004245
NM_201631
TGM5

transglutaminase 5

chr10_+_70482210 0.367 CCAR1
cell division cycle and apoptosis regulator 1
chr6_+_26501448 0.366 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1
chr12_+_12224401 0.364 NM_030766
NM_138722
BCL2L14

BCL2-like 14 (apoptosis facilitator)

chr3_-_39234071 0.363 NM_194293
NM_001198621
XIRP1

xin actin-binding repeat containing 1

chr6_-_13295817 0.363 NM_001242698
LOC100130357
uncharacterized LOC100130357
chr6_-_38563763 0.362 NM_001172418
NM_152733
BTBD9

BTB (POZ) domain containing 9

chr5_-_159797618 0.362 NM_031908
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr10_+_54074037 0.359 NM_012242
DKK1
dickkopf 1 homolog (Xenopus laevis)
chr11_+_2924504 0.358 SLC22A18
solute carrier family 22, member 18
chrX_+_153775561 0.357 NM_001099857
NM_001145255
IKBKG

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

chr3_-_127541160 0.357 NM_007283
MGLL
monoglyceride lipase
chr1_+_23037329 0.354 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr2_+_46926049 0.353 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr16_-_67217403 0.352 KIAA0895L
KIAA0895-like
chr20_-_62601140 0.349 NM_020713
ZNF512B
zinc finger protein 512B
chr9_-_130540911 0.347 NM_170600
SH2D3C
SH2 domain containing 3C
chr21_+_46117086 0.346 NM_198699
KRTAP10-12
keratin associated protein 10-12
chr6_+_147527102 0.345 STXBP5
syntaxin binding protein 5 (tomosyn)
chr4_-_157892466 0.345 PDGFC
platelet derived growth factor C
chr12_-_63328663 0.343 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr6_+_29274402 0.343 NM_030946
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr7_-_137686814 0.340 NM_001253775
NM_194071
CREB3L2

cAMP responsive element binding protein 3-like 2

chr10_-_49812996 0.338 NM_021226
ARHGAP22
Rho GTPase activating protein 22
chr6_+_157802479 0.332 NM_024630
NM_153746
ZDHHC14

zinc finger, DHHC-type containing 14

chr10_-_88853826 0.328 GLUD1
glutamate dehydrogenase 1
chr5_+_110559647 0.328 NM_001744
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr20_-_45976626 0.328 ZMYND8
zinc finger, MYND-type containing 8
chr17_-_67138013 0.327 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr9_+_2622052 0.326 VLDLR
very low density lipoprotein receptor
chr15_+_33010174 0.326 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr12_+_65672422 0.324 NM_001031679
NM_001193460
NM_198080
MSRB3


methionine sulfoxide reductase B3


chr16_+_50775960 0.321 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr8_-_72268720 0.321 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr10_+_94608224 0.321 NM_019053
EXOC6
exocyst complex component 6
chr4_-_185747183 0.320 NM_001995
ACSL1
acyl-CoA synthetase long-chain family member 1
chr5_+_141348731 0.320 RNF14
ring finger protein 14
chr9_+_2622099 0.319 VLDLR
very low density lipoprotein receptor
chr19_-_48547180 0.318 NM_019855
CABP5
calcium binding protein 5
chr12_+_59989847 0.318 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chrX_-_153775774 0.317 NM_001042351
G6PD
glucose-6-phosphate dehydrogenase
chr2_+_24807345 0.316 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr1_-_144997110 0.312 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr9_-_8733893 0.310 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr19_-_39390168 0.310 NM_012237
NM_001193286
NM_030593
SIRT2


sirtuin 2


chr1_-_169599349 0.310 NM_003005
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr18_+_31158540 0.307 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr15_+_89739234 0.306 ABHD2
abhydrolase domain containing 2
chr1_-_57044980 0.306 PPAP2B
phosphatidic acid phosphatase type 2B
chr4_-_157892054 0.306 PDGFC
platelet derived growth factor C
chr7_+_30951414 0.304 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr1_+_145524989 0.303 NM_003637
ITGA10
integrin, alpha 10
chr4_+_113970784 0.303 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr3_+_46395574 0.302 CCR2
chemokine (C-C motif) receptor 2
chr9_+_2622134 0.300 VLDLR
very low density lipoprotein receptor
chr22_+_50946627 0.299 NM_001185011
NM_014551
NM_152299
NCAPH2


non-SMC condensin II complex, subunit H2


chr21_+_34922923 0.298 SON
SON DNA binding protein
chr18_+_54318561 0.298 NM_015285
NM_052834
WDR7

WD repeat domain 7

chr1_-_86043932 0.298 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr3_+_50388255 0.296 NM_007022
CYB561D2
cytochrome b-561 domain containing 2
chr13_-_50699775 0.296 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chrX_-_99665270 0.295 NM_001105243
NM_001184880
NM_020766
PCDH19


protocadherin 19


chr2_-_233352530 0.295 NM_004826
ECEL1
endothelin converting enzyme-like 1
chr16_-_12897632 0.295 CPPED1
calcineurin-like phosphoesterase domain containing 1
chr8_+_17434700 0.294 PDGFRL
platelet-derived growth factor receptor-like
chr4_+_77870944 0.292 SEPT11
septin 11
chr1_+_43291230 0.290 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr4_+_128886379 0.289 NM_001039717
C4orf29
chromosome 4 open reading frame 29
chr12_-_112819755 0.288 NM_001109662
C12orf51
chromosome 12 open reading frame 51
chr7_+_123249076 0.288 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr7_+_154720154 0.288 LOC100132707
uncharacterized LOC100132707

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
11.03 3.71e-02 GO:0015791 polyol transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 5.56e-03 GO:0016020 membrane
1.20 1.44e-02 GO:0071944 cell periphery
1.20 1.65e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 3.31e-02 GO:0005515 protein binding