Motif ID: UAUUGCU

Z-value: 0.918


Mature miRNA associated with seed UAUUGCU:

NamemiRBase Accession
hsa-miR-137 MIMAT0000429



Activity profile for motif UAUUGCU.

activity profile for motif UAUUGCU


Sorted Z-values histogram for motif UAUUGCU

Sorted Z-values for motif UAUUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of UAUUGCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_119800004 0.609 NM_016644
PRR16
proline rich 16
chr8_+_70405027 0.497 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr8_+_70378858 0.484 NM_001128204
NM_015170
SULF1

sulfatase 1

chr14_-_89883306 0.466 NM_005197
FOXN3
forkhead box N3
chr5_-_111312522 0.427 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr5_-_111092918 0.426 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr5_-_111093030 0.424 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr5_-_111093251 0.421 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr5_-_111093792 0.415 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr3_+_69812961 0.414 NM_006722
MITF
microphthalmia-associated transcription factor
chr14_-_90085325 0.413 NM_001085471
FOXN3
forkhead box N3
chr3_+_69915374 0.410 NM_198177
MITF
microphthalmia-associated transcription factor
chr3_+_69812620 0.405 NM_001184967
MITF
microphthalmia-associated transcription factor
chr2_+_30454396 0.377 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr3_+_69788562 0.373 NM_198159
MITF
microphthalmia-associated transcription factor
chr4_-_142054431 0.354 NM_020724
RNF150
ring finger protein 150
chr1_+_213123853 0.317 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr19_+_50030874 0.313 NM_020650
RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr17_-_74236272 0.311 NM_052916
RNF157
ring finger protein 157
chr3_+_69985750 0.284 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr12_-_53074172 0.271 NM_006121
KRT1
keratin 1
chr13_+_32605436 0.264 NM_023037
FRY
furry homolog (Drosophila)
chrX_+_16964730 0.263 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr1_-_46598250 0.261 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr11_-_66335958 0.250 NM_003793
CTSF
cathepsin F
chr1_-_232651227 0.243 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr22_-_29075708 0.242 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr5_-_111091947 0.241 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr10_+_92980322 0.240 NM_032373
PCGF5
polycomb group ring finger 5
chr11_-_64570621 0.238 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chrX_-_154033729 0.229 NM_001166460
NM_001166461
NM_001166462
NM_002436
MPP1



membrane protein, palmitoylated 1, 55kDa



chr18_+_11981421 0.222 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr19_+_10543110 0.222 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr17_-_26662439 0.220 NM_174887
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chr7_+_28475233 0.215 NM_004904
CREB5
cAMP responsive element binding protein 5
chr5_-_93447237 0.213 NM_001163417
NM_001163418
NM_032042
FAM172A


family with sequence similarity 172, member A


chr19_+_10541334 0.212 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr3_+_20081523 0.211 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chr7_+_28725597 0.204 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr19_+_10531128 0.204 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr16_+_12995454 0.203 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr6_-_37467688 0.203 NM_138493
CCDC167
coiled-coil domain containing 167
chr12_+_65672422 0.201 NM_001031679
NM_001193460
NM_198080
MSRB3


methionine sulfoxide reductase B3


chr5_-_172198160 0.200 NM_004417
DUSP1
dual specificity phosphatase 1
chr5_-_171710794 0.200 NM_152277
UBTD2
ubiquitin domain containing 2
chr18_-_70534809 0.198 NM_001201465
NM_138966
NETO1

neuropilin (NRP) and tolloid (TLL)-like 1

chr7_+_28338939 0.195 NM_182899
CREB5
cAMP responsive element binding protein 5
chr5_+_133861685 0.194 NM_015288
PHF15
PHD finger protein 15
chr5_-_151138139 0.194 NM_004045
ATOX1
ATX1 antioxidant protein 1 homolog (yeast)
chr2_-_224702300 0.193 NM_001039569
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr10_-_72141347 0.191 NM_207119
LRRC20
leucine rich repeat containing 20
chr20_-_42839423 0.190 NM_016470
C20orf111
chromosome 20 open reading frame 111
chr12_+_65672682 0.189 NM_001193461
MSRB3
methionine sulfoxide reductase B3
chr19_+_10563581 0.188 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chr7_+_28452143 0.188 NM_182898
CREB5
cAMP responsive element binding protein 5
chr11_+_63997752 0.188 NM_005528
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr15_-_58358120 0.188 NM_001206897
NM_003888
NM_170696
ALDH1A2


aldehyde dehydrogenase 1 family, member A2


chr7_-_139477437 0.185 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr6_+_56819706 0.183 NM_152731
BEND6
BEN domain containing 6
chr6_+_69344939 0.183 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr4_+_37892698 0.181 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr12_+_15699277 0.181 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr22_+_42372763 0.179 NM_019106
NM_145733
SEPT3

septin 3

chr5_-_127873734 0.179 NM_001999
FBN2
fibrillin 2
chrX_-_39956655 0.178 NM_001123385
NM_017745
BCOR

BCL6 corepressor

chr14_+_76071804 0.177 NM_001195283
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr20_+_54933982 0.176 NM_080821
FAM210B
family with sequence similarity 210, member B
chr13_-_67804432 0.174 NM_020403
NM_203487
PCDH9

protocadherin 9

chrX_+_9754465 0.173 NM_001649
SHROOM2
shroom family member 2
chr12_+_26126687 0.171 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr7_-_19157262 0.169 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr14_+_53196852 0.169 NM_001130701
NM_145251
STYX

serine/threonine/tyrosine interacting protein

chr19_+_47104490 0.168 NM_005184
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr2_+_24807345 0.165 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chrX_+_108780235 0.164 NM_001242618
NXT2
nuclear transport factor 2-like export factor 2
chr3_+_170139027 0.162 NM_001185056
CLDN11
claudin 11
chr10_-_72142344 0.162 NM_018205
NM_018239
LRRC20

leucine rich repeat containing 20

chr12_+_120105656 0.162 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr20_-_3149070 0.161 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr12_+_15475190 0.161 NM_002848
NM_030667
PTPRO

protein tyrosine phosphatase, receptor type, O

chr18_-_30050394 0.161 NM_001242409
NM_022751
FAM59A

family with sequence similarity 59, member A

chr1_-_47134039 0.160 NM_001042546
NM_022745
ATPAF1

ATP synthase mitochondrial F1 complex assembly factor 1

chr5_-_107717798 0.159 NM_001163315
FBXL17
F-box and leucine-rich repeat protein 17
chr1_-_38471170 0.159 NM_001243878
NM_004468
FHL3

four and a half LIM domains 3

chr6_+_11538486 0.159 NM_001100829
TMEM170B
transmembrane protein 170B
chr19_-_51858041 0.158 NM_001014763
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr10_+_134351272 0.157 NM_005539
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr1_+_244216506 0.157 NM_006352
ZNF238
zinc finger protein 238
chr2_-_198175494 0.156 NM_001195144
NM_153697
ANKRD44

ankyrin repeat domain 44

chrX_+_108779009 0.154 NM_018698
NXT2
nuclear transport factor 2-like export factor 2
chr20_-_32262254 0.153 NM_031231
NM_031232
NECAB3

N-terminal EF-hand calcium binding protein 3

chr1_+_244214552 0.152 NM_205768
ZNF238
zinc finger protein 238
chr12_-_54121203 0.152 NM_001143682
NM_020898
CALCOCO1

calcium binding and coiled-coil domain 1

chr12_-_15942350 0.150 NM_004447
EPS8
epidermal growth factor receptor pathway substrate 8
chr3_+_170136652 0.149 NM_005602
CLDN11
claudin 11
chr6_-_8064642 0.149 NM_001199322
NM_001199323
NM_201280
MUTED


muted homolog (mouse)


chr4_-_78740508 0.148 NM_144571
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr15_-_58306185 0.148 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr16_+_4382224 0.146 NM_032575
GLIS2
GLIS family zinc finger 2
chr12_+_26205490 0.146 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr3_+_185000714 0.145 NM_001242314
NM_001242317
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr14_+_76044939 0.145 NM_017791
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr20_-_25566137 0.143 NM_025176
NINL
ninein-like
chrX_+_108780058 0.143 NM_001242617
NXT2
nuclear transport factor 2-like export factor 2
chr22_+_31090792 0.142 NM_030758
OSBP2
oxysterol binding protein 2
chr11_-_106888829 0.141 NM_000855
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chr12_-_31743822 0.141 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr5_-_65017874 0.139 NM_019072
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr20_-_42816217 0.138 NM_020433
NM_175913
JPH2

junctophilin 2

chr19_-_51869632 0.136 NM_001985
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr3_+_127391768 0.135 NM_032548
NM_172027
ABTB1

ankyrin repeat and BTB (POZ) domain containing 1

chr9_+_34990266 0.134 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr5_+_112312392 0.133 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chr8_-_74791098 0.128 NM_001001481
NM_018299
UBE2W

ubiquitin-conjugating enzyme E2W (putative)

chr1_+_16693582 0.128 NM_001114600
NM_015609
C1orf144

chromosome 1 open reading frame 144

chr19_+_47778099 0.128 NM_178511
PRR24
proline rich 24
chr16_+_21610812 0.128 NM_001077180
NM_016025
METTL9

methyltransferase like 9

chr7_-_141401889 0.126 NM_001080392
KIAA1147
KIAA1147
chr2_-_43453737 0.125 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr3_-_127541975 0.124 NM_001003794
MGLL
monoglyceride lipase
chr3_+_43732358 0.123 NM_016006
ABHD5
abhydrolase domain containing 5
chr9_-_138987096 0.123 NM_144653
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr11_-_10562689 0.123 NM_016422
RNF141
ring finger protein 141
chr20_-_52199635 0.121 NM_006526
ZNF217
zinc finger protein 217
chr20_+_46130600 0.121 NM_001174087
NM_001174088
NM_006534
NM_181659
NCOA3



nuclear receptor coactivator 3



chr11_-_70935807 0.120 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr16_+_1203240 0.119 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr13_+_23755059 0.119 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr2_+_113033146 0.119 NM_198581
ZC3H6
zinc finger CCCH-type containing 6
chr5_+_139944411 0.118 NM_080670
SLC35A4
solute carrier family 35, member A4
chr11_-_65640199 0.116 NM_016938
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr6_-_52441815 0.116 NM_012288
TRAM2
translocation associated membrane protein 2
chr4_+_89513597 0.115 NM_014606
HERC3
hect domain and RLD 3
chr6_-_111136407 0.114 NM_015076
CDK19
cyclin-dependent kinase 19
chr6_-_166796459 0.114 NM_016098
BRP44L
brain protein 44-like
chr11_-_70507911 0.114 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr1_+_61547625 0.114 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr12_+_32654976 0.113 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr16_+_4674819 0.113 NM_001142289
NM_001142290
NM_001142291
NM_015246
MGRN1



mahogunin, ring finger 1



chr1_-_72748147 0.113 NM_173808
NEGR1
neuronal growth regulator 1
chr1_+_36273786 0.113 NM_017629
EIF2C4
eukaryotic translation initiation factor 2C, 4
chr9_-_125590809 0.111 NM_005388
PDCL
phosducin-like
chr3_-_52569021 0.110 NM_022908
NT5DC2
5'-nucleotidase domain containing 2
chr5_-_133968463 0.109 NM_001033503
NM_016103
SAR1B

SAR1 homolog B (S. cerevisiae)

chr2_-_128100673 0.109 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr14_+_75898836 0.109 NM_001135049
JDP2
Jun dimerization protein 2
chr9_+_112887780 0.108 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr4_-_184580104 0.108 NM_152682
RWDD4
RWD domain containing 4
chr10_-_35103894 0.107 NM_001184785
NM_001184786
NM_001184787
NM_001184788
NM_001184789
NM_001184790
NM_001184791
NM_001184792
NM_001184793
NM_001184794
NM_019619
PARD3










par-3 partitioning defective 3 homolog (C. elegans)










chr8_-_40755328 0.107 NM_001135731
NM_024645
ZMAT4

zinc finger, matrin-type 4

chr12_-_121734543 0.105 NM_172226
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr8_-_52811707 0.105 NM_052937
PCMTD1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr7_+_150068252 0.105 NM_014374
REPIN1
replication initiator 1
chr17_-_47439326 0.105 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr3_+_29322802 0.105 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr9_+_102668904 0.104 NM_017919
STX17
syntaxin 17
chr17_-_40337384 0.103 NM_001524
HCRT
hypocretin (orexin) neuropeptide precursor
chr20_-_1373744 0.103 NM_000801
NM_001199786
NM_054014
FKBP1A


FK506 binding protein 1A, 12kDa


chr22_-_44708730 0.103 NM_001099294
KIAA1644
KIAA1644
chrX_-_40036581 0.103 NM_001123383
NM_001123384
BCOR

BCL6 corepressor

chr9_+_4679557 0.103 NM_017913
CDC37L1
cell division cycle 37 homolog (S. cerevisiae)-like 1
chr3_-_127541160 0.102 NM_007283
MGLL
monoglyceride lipase
chr10_-_7453412 0.101 NM_001029880
SFMBT2
Scm-like with four mbt domains 2
chr9_+_112810877 0.101 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr12_+_120972103 0.101 NM_014868
RNF10
ring finger protein 10
chr21_+_45345278 0.101 NM_001037553
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr1_-_205719340 0.101 NM_022731
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr17_+_44668034 0.101 NM_006178
NSF
N-ethylmaleimide-sensitive factor
chr21_+_45285101 0.100 NM_020132
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr9_-_91793681 0.098 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr20_+_32150139 0.098 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr22_-_33454328 0.097 NM_001135774
SYN3
synapsin III
chr2_-_73460326 0.097 NM_032319
PRADC1
protease-associated domain containing 1
chr19_+_16435632 0.097 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr19_+_35759880 0.096 NM_003367
NM_207291
USF2

upstream transcription factor 2, c-fos interacting

chr1_+_61542928 0.096 NM_001145511
NFIA
nuclear factor I/A
chr12_+_104458235 0.096 NM_013320
HCFC2
host cell factor C2
chr7_-_44105162 0.096 NM_000290
PGAM2
phosphoglycerate mutase 2 (muscle)
chr16_+_11762235 0.095 NM_003498
SNN
stannin
chr16_-_31021716 0.095 NM_052874
STX1B
syntaxin 1B
chr2_-_213403280 0.095 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr10_-_7451198 0.094 NM_001018039
SFMBT2
Scm-like with four mbt domains 2
chr1_+_61547388 0.094 NM_001145512
NFIA
nuclear factor I/A
chr20_-_5591487 0.094 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr2_-_180129245 0.094 NM_178123
SESTD1
SEC14 and spectrin domains 1
chr14_+_75894508 0.093 NM_001135047
JDP2
Jun dimerization protein 2
chr16_-_67450149 0.093 NM_013304
ZDHHC1
zinc finger, DHHC-type containing 1
chr19_-_40971623 0.092 NM_000713
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr8_-_29206321 0.092 NM_057158
DUSP4
dual specificity phosphatase 4
chr2_+_149402559 0.092 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr6_-_52926588 0.092 NM_014920
NM_016513
ICK

intestinal cell (MAK-like) kinase

chr17_-_1395950 0.091 NM_001080779
MYO1C
myosin IC
chr8_+_26240522 0.091 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr15_-_79298001 0.091 NM_153815
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr10_-_64578926 0.090 NM_001136178
EGR2
early growth response 2
chr1_+_236305831 0.090 NM_003272
GPR137B
G protein-coupled receptor 137B
chr21_-_44846927 0.089 NM_173354
SIK1
salt-inducible kinase 1
chr3_-_100712248 0.089 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr9_+_34989637 0.089 NM_001135004
NM_012266
DNAJB5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr22_-_47134130 0.088 NM_022766
CERK
ceramide kinase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 9.60e-07 GO:0050794 regulation of cellular process
1.33 1.42e-06 GO:0050789 regulation of biological process
1.29 1.12e-05 GO:0065007 biological regulation
2.09 1.19e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.72 3.21e-04 GO:0006464 protein modification process
1.40 4.83e-04 GO:0044260 cellular macromolecule metabolic process
1.48 6.92e-04 GO:0060255 regulation of macromolecule metabolic process
1.45 9.86e-04 GO:0031323 regulation of cellular metabolic process
1.45 1.19e-03 GO:0080090 regulation of primary metabolic process
1.65 1.71e-03 GO:0043412 macromolecule modification
1.41 2.72e-03 GO:0019222 regulation of metabolic process
1.54 3.17e-03 GO:0044267 cellular protein metabolic process
1.52 5.13e-03 GO:0010468 regulation of gene expression
1.33 5.90e-03 GO:0043170 macromolecule metabolic process
2.76 1.80e-02 GO:0061061 muscle structure development
1.69 3.37e-02 GO:0035556 intracellular signal transduction
7.51 4.36e-02 GO:0043488 regulation of mRNA stability
3.04 4.40e-02 GO:0007517 muscle organ development
1.48 4.52e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.36 4.53e-02 GO:0023052 signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 1.51e-06 GO:0005622 intracellular
1.18 2.55e-06 GO:0044424 intracellular part
1.21 1.97e-03 GO:0005737 cytoplasm
1.28 5.31e-03 GO:0005634 nucleus
1.16 1.30e-02 GO:0043226 organelle
1.16 1.56e-02 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.28 3.52e-05 GO:0005515 protein binding
1.13 1.64e-03 GO:0005488 binding
1.84 3.78e-03 GO:0001071 nucleic acid binding transcription factor activity
1.84 3.78e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.77 1.49e-02 GO:0030528 transcription regulator activity
2.62 1.54e-02 GO:0016881 acid-amino acid ligase activity
1.46 2.18e-02 GO:0003677 DNA binding
2.71 2.21e-02 GO:0019787 small conjugating protein ligase activity
2.15 3.81e-02 GO:0004674 protein serine/threonine kinase activity