Motif ID: UCCCUUU

Z-value: 0.763


Mature miRNA associated with seed UCCCUUU:

NamemiRBase Accession
hsa-miR-204 MIMAT0000265
hsa-miR-211 MIMAT0000268



Activity profile for motif UCCCUUU.

activity profile for motif UCCCUUU


Sorted Z-values histogram for motif UCCCUUU

Sorted Z-values for motif UCCCUUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCCCUUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_142552547 0.919 NM_004445
EPHB6
EPH receptor B6
chr5_+_95066628 0.884 NM_014899
RHOBTB3
Rho-related BTB domain containing 3
chr5_-_9546157 0.743 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr1_+_170633312 0.690 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr8_-_108510094 0.606 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr1_+_183605207 0.476 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr9_+_91605777 0.427 NM_001001938
NM_001142413
C9orf47

chromosome 9 open reading frame 47

chr20_+_35169876 0.379 NM_006097
NM_181526
MYL9

myosin, light chain 9, regulatory

chr22_-_29075708 0.362 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr13_-_33760215 0.359 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr8_-_60031545 0.349 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr13_-_33780142 0.335 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr1_-_236228476 0.334 NM_002508
NID1
nidogen 1
chr13_-_33859835 0.331 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr10_-_81205091 0.322 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chrX_-_15873094 0.312 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr1_+_79086087 0.306 NM_006820
IFI44L
interferon-induced protein 44-like
chr12_-_108714438 0.306 NM_001142345
CMKLR1
chemokine-like receptor 1
chrX_-_142722869 0.306 NM_173078
SLITRK4
SLIT and NTRK-like family, member 4
chr1_+_159141376 0.301 NM_021189
NM_001127173
CADM3

cell adhesion molecule 3

chr12_-_108733075 0.289 NM_001142343
NM_001142344
NM_004072
CMKLR1


chemokine-like receptor 1


chrX_-_142722318 0.288 NM_001184750
SLITRK4
SLIT and NTRK-like family, member 4
chr18_-_25757351 0.272 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr17_+_47074749 0.272 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr6_-_46293628 0.267 NM_005822
RCAN2
regulator of calcineurin 2
chr5_+_71403040 0.264 NM_005909
MAP1B
microtubule-associated protein 1B
chr2_-_38303307 0.258 NM_000104
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chrX_-_142723921 0.252 NM_001184749
SLITRK4
SLIT and NTRK-like family, member 4
chr15_+_33010174 0.248 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chrX_+_16964730 0.235 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr19_-_11308184 0.234 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chr5_+_156693051 0.226 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr19_+_54926604 0.221 NM_001005367
NM_001201461
NM_020659
TTYH1


tweety homolog 1 (Drosophila)


chr17_-_19290471 0.221 NM_001198695
NM_002404
MFAP4

microfibrillar-associated protein 4

chr9_+_4985243 0.221 NM_004972
JAK2
Janus kinase 2
chr2_+_102770401 0.217 NM_000877
IL1R1
interleukin 1 receptor, type I
chr7_-_139477437 0.216 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr2_+_241938254 0.215 NM_001080437
SNED1
sushi, nidogen and EGF-like domains 1
chr10_-_21463019 0.215 NM_001173484
NM_213569
NEBL

nebulette

chr2_-_214016332 0.213 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr6_-_52441815 0.209 NM_012288
TRAM2
translocation associated membrane protein 2
chr9_+_90112754 0.209 NM_004938
DAPK1
death-associated protein kinase 1
chr6_+_126102278 0.209 NM_001199619
NM_001199620
NCOA7

nuclear receptor coactivator 7

chr4_-_142054431 0.207 NM_020724
RNF150
ring finger protein 150
chr6_+_136172802 0.207 NM_018945
PDE7B
phosphodiesterase 7B
chr16_-_73082169 0.201 NM_006885
ZFHX3
zinc finger homeobox 3
chr15_-_48937795 0.199 NM_000138
FBN1
fibrillin 1
chr20_+_34700257 0.197 NM_177996
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr5_+_156696351 0.197 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr14_-_61115906 0.195 NM_005982
SIX1
SIX homeobox 1
chr2_+_33172368 0.191 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr5_-_179780314 0.191 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr5_+_32711437 0.191 NM_000908
NM_001204375
NPR3

natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)

chr8_+_77593506 0.191 NM_024721
ZFHX4
zinc finger homeobox 4
chr2_-_230135954 0.190 NM_001100818
NM_017933
PID1

phosphotyrosine interaction domain containing 1

chr15_+_91643429 0.190 NM_014848
SV2B
synaptic vesicle glycoprotein 2B
chr19_-_11305186 0.189 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr3_-_9811628 0.188 NM_003656
CAMK1
calcium/calmodulin-dependent protein kinase I
chr5_+_32710742 0.188 NM_001204376
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr3_+_154797644 0.188 NM_007287
MME
membrane metallo-endopeptidase
chr5_+_172261220 0.187 NM_001031711
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr4_+_55095263 0.187 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr3_+_154797435 0.187 NM_000902
MME
membrane metallo-endopeptidase
chr8_-_91657898 0.187 NM_001008495
NM_001146273
TMEM64

transmembrane protein 64

chr2_+_33359607 0.187 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr4_-_57522469 0.186 NM_001145459
NM_139211
HOPX

HOP homeobox

chr5_-_127873734 0.185 NM_001999
FBN2
fibrillin 2
chr20_+_34742656 0.182 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr3_+_154797910 0.182 NM_007288
MME
membrane metallo-endopeptidase
chr13_-_67804432 0.180 NM_020403
NM_203487
PCDH9

protocadherin 9

chr3_+_154798078 0.179 NM_007289
MME
membrane metallo-endopeptidase
chr11_-_65640199 0.178 NM_016938
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr5_-_142783225 0.173 NM_000176
NM_001020825
NM_001024094
NM_001204258
NM_001204259
NM_001204260
NM_001204261
NM_001204262
NM_001204263
NM_001204264
NM_001204265
NR3C1










nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)










chr2_+_23608297 0.171 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr5_-_126366439 0.171 NM_178450
MARCH3
membrane-associated ring finger (C3HC4) 3
chr10_-_75910525 0.169 NM_012095
NM_207012
AP3M1

adaptor-related protein complex 3, mu 1 subunit

chr10_-_62703822 0.169 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr4_-_57547845 0.169 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr9_+_4490193 0.166 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr2_+_210288668 0.166 NM_001039538
MAP2
microtubule-associated protein 2
chr8_-_95961543 0.162 NM_001135733
NM_033285
TP53INP1

tumor protein p53 inducible nuclear protein 1

chr7_+_117824085 0.161 NM_016200
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chrX_-_62975005 0.161 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr2_+_210444364 0.160 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr15_+_41523401 0.158 NM_007236
CHP
calcium binding protein P22
chr17_-_76921453 0.156 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr6_+_160390128 0.156 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr5_-_146889618 0.156 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr10_-_21186530 0.156 NM_006393
NEBL
nebulette
chr7_-_105319608 0.155 NM_138495
ATXN7L1
ataxin 7-like 1
chr20_+_56884749 0.154 NM_020673
RAB22A
RAB22A, member RAS oncogene family
chr20_-_3388219 0.153 NM_001009984
C20orf194
chromosome 20 open reading frame 194
chr1_-_163172624 0.153 NM_001195303
RGS5
regulator of G-protein signaling 5
chr14_+_76071804 0.152 NM_001195283
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr5_-_146833150 0.151 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chrX_-_63005212 0.149 NM_001173479
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr9_+_91606349 0.147 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chr1_-_163172863 0.146 NM_003617
RGS5
regulator of G-protein signaling 5
chrX_-_18372777 0.144 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr22_+_42086546 0.143 NM_001142964
C22orf46
chromosome 22 open reading frame 46
chr18_-_3011944 0.142 NM_014646
LPIN2
lipin 2
chr17_+_41323181 0.142 NM_005899
NBR1
neighbor of BRCA1 gene 1
chr8_-_17271015 0.140 NM_004686
MTMR7
myotubularin related protein 7
chr12_-_22487566 0.139 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr6_+_126111782 0.138 NM_001122842
NM_001199621
NM_181782
NCOA7


nuclear receptor coactivator 7


chr7_-_141646716 0.136 NM_013252
CLEC5A
C-type lectin domain family 5, member A
chr1_+_192778168 0.136 NM_002923
RGS2
regulator of G-protein signaling 2, 24kDa
chr14_+_76044939 0.136 NM_017791
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr5_-_10761344 0.136 NM_004394
DAP
death-associated protein
chr5_+_76011780 0.133 NM_001992
F2R
coagulation factor II (thrombin) receptor
chr3_-_145968958 0.133 NM_001128306
NM_001177304
NM_020353
PLSCR4


phospholipid scramblase 4


chr2_-_200335988 0.132 NM_015265
SATB2
SATB homeobox 2
chr13_-_114898084 0.132 NM_007368
RASA3
RAS p21 protein activator 3
chr3_-_122134881 0.131 NM_019069
WDR5B
WD repeat domain 5B
chr14_-_89883306 0.131 NM_005197
FOXN3
forkhead box N3
chrX_-_99986496 0.131 NM_001174068
NM_080737
SYTL4

synaptotagmin-like 4

chr18_-_55470279 0.130 NM_005603
ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr3_-_58563490 0.130 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chr3_-_48700317 0.126 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr6_-_167275657 0.125 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chrX_-_99987072 0.125 NM_001129896
SYTL4
synaptotagmin-like 4
chr2_-_200329810 0.124 NM_001172517
SATB2
SATB homeobox 2
chr16_-_49860917 0.124 NM_015069
ZNF423
zinc finger protein 423
chr18_-_65183922 0.124 NM_032160
DSEL
dermatan sulfate epimerase-like
chrX_-_134429958 0.124 NM_001185063
NM_007131
ZNF75D

zinc finger protein 75D

chr20_+_56964162 0.123 NM_001195677
NM_004738
VAPB

VAMP (vesicle-associated membrane protein)-associated protein B and C

chr2_-_200322699 0.122 NM_001172509
SATB2
SATB homeobox 2
chrX_+_57618268 0.121 NM_007157
ZXDB
zinc finger, X-linked, duplicated B
chr6_-_167040700 0.121 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_+_159750756 0.120 NM_017823
DUSP23
dual specificity phosphatase 23
chr2_-_214015053 0.120 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr2_-_175499275 0.119 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr2_-_175547471 0.119 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr9_-_73029539 0.118 NM_001206
KLF9
Kruppel-like factor 9
chr22_-_44893903 0.116 NM_032287
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr9_+_127539382 0.115 NM_182487
OLFML2A
olfactomedin-like 2A
chr4_-_114682836 0.114 NM_001221
NM_172114
NM_172115
NM_172127
NM_172128
NM_172129
CAMK2D





calcium/calmodulin-dependent protein kinase II delta





chr13_-_74707913 0.114 NM_007249
KLF12
Kruppel-like factor 12
chr6_+_126240369 0.113 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr3_-_87040246 0.112 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr4_-_25161908 0.111 NM_016955
SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr22_-_32341298 0.111 NM_015372
C22orf24
chromosome 22 open reading frame 24
chr14_-_90085325 0.111 NM_001085471
FOXN3
forkhead box N3
chr20_-_36889173 0.110 NM_001029864
KIAA1755
KIAA1755
chr17_-_15165873 0.110 NM_153321
PMP22
peripheral myelin protein 22
chr1_+_201708940 0.109 NM_001167738
NAV1
neuron navigator 1
chr8_+_42995553 0.109 NM_152419
HGSNAT
heparan-alpha-glucosaminide N-acetyltransferase
chr8_+_79428335 0.109 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr17_-_15164043 0.107 NM_153322
PMP22
peripheral myelin protein 22
chr7_-_16685360 0.107 NM_020319
ANKMY2
ankyrin repeat and MYND domain containing 2
chr2_-_127963342 0.107 NM_001001665
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr17_-_15168590 0.106 NM_000304
PMP22
peripheral myelin protein 22
chr11_-_33744272 0.106 NM_001127223
NM_001127225
NM_001127226
CD59


CD59 molecule, complement regulatory protein


chr1_-_46598250 0.106 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr6_+_10555948 0.105 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr5_-_55290601 0.105 NM_001190981
NM_002184
NM_175767
IL6ST


interleukin 6 signal transducer (gp130, oncostatin M receptor)


chr6_-_74363689 0.105 NM_012434
SLC17A5
solute carrier family 17 (anion/sugar transporter), member 5
chr19_-_38714781 0.105 NM_001135155
NM_004647
DPF1

D4, zinc and double PHD fingers family 1

chr12_-_49182718 0.105 NM_020983
ADCY6
adenylate cyclase 6
chr13_+_32605436 0.104 NM_023037
FRY
furry homolog (Drosophila)
chr1_+_164528586 0.103 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr17_+_61699786 0.103 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr12_-_133532847 0.102 NM_183238
NM_001164715
ZNF605

zinc finger protein 605

chr6_+_10585978 0.102 NM_145655
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr2_+_65216482 0.102 NM_003038
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr12_-_109125289 0.102 NM_014325
CORO1C
coronin, actin binding protein, 1C
chr9_+_118916069 0.101 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr16_+_8768403 0.100 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr8_-_27472298 0.100 NM_001831
CLU
clusterin
chr1_+_201617449 0.099 NM_020443
NAV1
neuron navigator 1
chr11_-_33744497 0.099 NM_001127227
CD59
CD59 molecule, complement regulatory protein
chr10_-_79397546 0.098 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr17_+_41322413 0.098 NM_031862
NM_031858
NBR1

neighbor of BRCA1 gene 1

chr19_-_15391261 0.097 NM_014299
NM_058243
BRD4

bromodomain containing 4

chr14_-_69619870 0.097 NM_003861
DCAF5
DDB1 and CUL4 associated factor 5
chr12_+_133757994 0.096 NM_001165883
NM_001165884
NM_001165885
NM_001165886
NM_001165887
NM_003415
NM_152943
NM_001165881
NM_001165882
ZNF268








zinc finger protein 268








chr2_+_201170603 0.096 NM_015535
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr9_-_113800243 0.096 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr1_-_184943673 0.096 NM_052966
FAM129A
family with sequence similarity 129, member A
chr5_-_81574198 0.095 NM_001025
RPS23
ribosomal protein S23
chr11_-_74109417 0.095 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr8_-_57123858 0.095 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr11_-_123065988 0.094 NM_024769
CLMP
CXADR-like membrane protein
chr6_+_10521564 0.093 NM_145649
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chrX_+_77166178 0.092 NM_000052
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr11_+_35684342 0.092 NM_017583
TRIM44
tripartite motif containing 44
chr3_+_45927995 0.092 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr1_-_84464728 0.091 NM_024686
TTLL7
tubulin tyrosine ligase-like family, member 7
chr10_+_120789227 0.091 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chrX_-_34675366 0.091 NM_031442
TMEM47
transmembrane protein 47
chr2_-_224702300 0.091 NM_001039569
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr20_-_3996035 0.090 NM_007219
NM_001134337
NM_001134338
RNF24


ring finger protein 24


chr5_+_76248679 0.090 NM_001882
CRHBP
corticotropin releasing hormone binding protein
chr5_+_140718353 0.090 NM_018915
NM_032009
PCDHGA2

protocadherin gamma subfamily A, 2

chr6_+_30524485 0.090 NM_001077497
NM_025263
PRR3

proline rich 3

chr16_+_30406711 0.089 NM_152652
ZNF48
zinc finger protein 48
chr1_-_55352920 0.089 NM_014762
DHCR24
24-dehydrocholesterol reductase
chr16_+_8814567 0.089 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr14_+_77228132 0.089 NM_014909
VASH1
vasohibin 1
chr13_-_29292961 0.089 NM_001135919
NM_181785
SLC46A3

solute carrier family 46, member 3


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.44 1.70e-03 GO:0006464 protein modification process
1.40 7.93e-03 GO:0043412 macromolecule modification
1.27 1.55e-02 GO:0051179 localization
1.26 2.01e-02 GO:0031323 regulation of cellular metabolic process
1.43 3.28e-02 GO:0007399 nervous system development
1.26 3.31e-02 GO:0080090 regulation of primary metabolic process
2.56 4.98e-02 GO:0007156 homophilic cell adhesion

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 3.14e-04 GO:0044464 cell part
1.06 3.23e-04 GO:0005623 cell
3.15 2.56e-03 GO:0030027 lamellipodium
2.34 4.91e-03 GO:0031252 cell leading edge
1.12 1.33e-02 GO:0043231 intracellular membrane-bounded organelle
1.14 1.44e-02 GO:0016020 membrane
1.09 1.54e-02 GO:0044424 intracellular part
1.12 1.57e-02 GO:0043227 membrane-bounded organelle
6.97 3.54e-02 GO:0010494 stress granule
1.08 4.65e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.33 9.99e-07 GO:0046872 metal ion binding
1.32 2.24e-06 GO:0043167 ion binding
1.32 2.51e-06 GO:0043169 cation binding
1.48 3.42e-06 GO:0008270 zinc ion binding
1.40 6.36e-05 GO:0046914 transition metal ion binding
1.09 2.94e-03 GO:0005488 binding
1.64 4.27e-03 GO:0019899 enzyme binding
2.10 1.54e-02 GO:0019900 kinase binding