Motif ID: UUGGCAC

Z-value: 0.578


Mature miRNA associated with seed UUGGCAC:

NamemiRBase Accession
hsa-miR-1271 MIMAT0005796
hsa-miR-96 MIMAT0000095



Activity profile for motif UUGGCAC.

activity profile for motif UUGGCAC


Sorted Z-values histogram for motif UUGGCAC

Sorted Z-values for motif UUGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGCAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_68165660 0.282 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_+_55095263 0.227 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr9_+_2621740 0.222 NM_001018056
NM_003383
VLDLR

very low density lipoprotein receptor

chr5_-_172756505 0.219 NM_003714
STC2
stanniocalcin 2
chr2_+_103236147 0.215 NM_003048
SLC9A2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr1_-_86043932 0.200 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chrX_+_30671456 0.197 NM_000167
NM_001128127
NM_001205019
NM_203391
GK



glycerol kinase



chr1_-_85930733 0.191 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr20_+_44650260 0.184 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chrX_-_107019001 0.182 NM_198057
TSC22D3
TSC22 domain family, member 3
chr17_+_47074749 0.181 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chrX_-_106960268 0.179 NM_004089
TSC22D3
TSC22 domain family, member 3
chr20_+_44657812 0.176 NM_020708
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr17_+_34136437 0.175 NM_003487
NM_139215
TAF15

TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa

chr12_-_96184510 0.172 NM_021229
NTN4
netrin 4
chr10_+_31608097 0.171 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr12_+_78225068 0.167 NM_014903
NAV3
neuron navigator 3
chr8_-_11324184 0.164 NM_053279
FAM167A
family with sequence similarity 167, member A
chr6_-_30710219 0.160 NM_005803
FLOT1
flotillin 1
chr12_+_32654976 0.160 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr8_+_97505876 0.159 NM_002998
SDC2
syndecan 2
chr10_+_31610063 0.156 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr1_+_9352931 0.156 NM_025106
SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr3_+_151985828 0.150 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr8_+_17354562 0.148 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr19_+_54369610 0.147 NM_001020820
MYADM
myeloid-associated differentiation marker
chr11_-_88796815 0.146 NM_000842
GRM5
glutamate receptor, metabotropic 5
chr2_-_68479481 0.146 NM_000945
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr1_-_236228476 0.145 NM_002508
NID1
nidogen 1
chr8_+_17396285 0.144 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr9_-_116061319 0.138 NM_145051
RNF183
ring finger protein 183
chr2_-_166060552 0.137 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr19_+_54372659 0.137 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr22_+_45704821 0.136 NM_001104595
FAM118A
family with sequence similarity 118, member A
chr12_+_60083125 0.135 NM_004731
SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr8_+_37654395 0.133 NM_032777
GPR124
G protein-coupled receptor 124
chr3_+_152017193 0.132 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr1_+_165796652 0.132 NM_012474
UCK2
uridine-cytidine kinase 2
chr10_+_92980322 0.131 NM_032373
PCGF5
polycomb group ring finger 5
chr2_-_44586854 0.130 NM_001042385
NM_001042386
PREPL

prolyl endopeptidase-like

chr20_+_361272 0.126 NM_021158
TRIB3
tribbles homolog 3 (Drosophila)
chr9_+_79056581 0.126 NM_001097634
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr7_-_131241321 0.123 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr9_+_79115548 0.123 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr7_+_98246595 0.122 NM_002523
NPTX2
neuronal pentraxin II
chr10_+_60937226 0.122 NM_001143774
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr3_+_179370779 0.122 NM_003940
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr6_+_36164528 0.121 NM_015695
BRPF3
bromodomain and PHD finger containing, 3
chr14_-_53620032 0.121 NM_001160147
NM_001160148
NM_030637
DDHD1


DDHD domain containing 1


chr10_-_62703822 0.121 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr22_+_45705766 0.120 NM_017911
FAM118A
family with sequence similarity 118, member A
chr22_+_21271619 0.119 NM_005207
CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chrX_-_118284541 0.118 NM_020721
KIAA1210
KIAA1210
chr19_+_54371125 0.118 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr17_-_78450247 0.117 NM_002522
NPTX1
neuronal pentraxin I
chr16_-_89043215 0.116 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr3_-_16555128 0.115 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr12_-_52604488 0.114 NM_001242696
LOC283403
uncharacterized LOC283403
chr1_-_227505796 0.114 NM_003607
NM_014826
CDC42BPA

CDC42 binding protein kinase alpha (DMPK-like)

chr6_+_30524485 0.114 NM_001077497
NM_025263
PRR3

proline rich 3

chr19_+_50168398 0.113 NM_001040668
NM_138639
BCL2L12

BCL2-like 12 (proline rich)

chr2_-_44587812 0.113 NM_006036
PREPL
prolyl endopeptidase-like
chrX_-_19688991 0.113 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr2_-_44588622 0.111 NM_001171606
NM_001171613
PREPL

prolyl endopeptidase-like

chr14_-_88737160 0.111 NM_138318
KCNK10
potassium channel, subfamily K, member 10
chr12_-_54653317 0.111 NM_001127322
CBX5
chromobox homolog 5
chr5_-_32313069 0.110 NM_001040446
MTMR12
myotubularin related protein 12
chr16_+_81348564 0.110 NM_022041
GAN
gigaxonin
chr2_-_224702300 0.109 NM_001039569
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chrX_+_16964730 0.109 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr17_+_80477564 0.109 NM_004514
FOXK2
forkhead box K2
chr12_-_54653369 0.107 NM_001127321
CBX5
chromobox homolog 5
chr2_-_100939194 0.107 NM_198461
LONRF2
LON peptidase N-terminal domain and ring finger 2
chr15_+_63481713 0.106 NM_016530
RAB8B
RAB8B, member RAS oncogene family
chr4_+_77870864 0.105 NM_018243
SEPT11
septin 11
chr10_+_134351272 0.105 NM_005539
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr16_-_1429612 0.104 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr11_-_47516072 0.104 NM_198700
CELF1
CUGBP, Elav-like family member 1
chr14_-_88793250 0.104 NM_021161
KCNK10
potassium channel, subfamily K, member 10
chr2_-_55646946 0.102 NM_001135597
NM_018084
CCDC88A

coiled-coil domain containing 88A

chr7_+_142985307 0.101 NM_032982
NM_032983
CASP2

caspase 2, apoptosis-related cysteine peptidase

chr6_+_34759743 0.101 NM_017754
UHRF1BP1
UHRF1 binding protein 1
chr9_+_79074067 0.101 NM_001097633
NM_001490
GCNT1

glucosaminyl (N-acetyl) transferase 1, core 2

chr2_+_201170603 0.101 NM_015535
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr9_+_79093256 0.101 NM_001097635
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr7_+_142986680 0.101 NM_001224
CASP2
caspase 2, apoptosis-related cysteine peptidase
chrX_-_19817907 0.099 NM_001024666
SH3KBP1
SH3-domain kinase binding protein 1
chr3_-_157823815 0.098 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr7_+_107110501 0.098 NM_005295
GPR22
G protein-coupled receptor 22
chr5_+_71403040 0.096 NM_005909
MAP1B
microtubule-associated protein 1B
chr16_-_25026650 0.096 NM_001006634
NM_018054
ARHGAP17

Rho GTPase activating protein 17

chr2_-_44588943 0.096 NM_001171603
NM_001171617
PREPL

prolyl endopeptidase-like

chr1_+_99729847 0.095 NM_001166252
NM_014839
LPPR4

lipid phosphate phosphatase-related protein type 4

chr10_-_100027943 0.093 NM_032211
LOXL4
lysyl oxidase-like 4
chr5_+_41904459 0.093 NM_175921
C5orf51
chromosome 5 open reading frame 51
chr11_-_47510518 0.092 NM_001025596
NM_001172640
CELF1

CUGBP, Elav-like family member 1

chr4_+_48343502 0.091 NM_020846
SLAIN2
SLAIN motif family, member 2
chr7_-_47621741 0.091 NM_022748
TNS3
tensin 3
chr14_+_92788924 0.091 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr9_+_131217433 0.090 NM_153436
ODF2
outer dense fiber of sperm tails 2
chr1_-_68962726 0.090 NM_001114120
NM_017779
DEPDC1

DEP domain containing 1

chr5_+_154092461 0.090 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr22_-_22307212 0.090 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr15_-_23086290 0.090 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr2_+_45878912 0.089 NM_005400
PRKCE
protein kinase C, epsilon
chr1_+_114447906 0.089 NM_022836
DCLRE1B
DNA cross-link repair 1B
chr11_-_88781039 0.089 NM_001143831
GRM5
glutamate receptor, metabotropic 5
chr9_+_131219185 0.088 NM_153437
ODF2
outer dense fiber of sperm tails 2
chr12_-_48213567 0.088 NM_001098416
NM_015401
HDAC7

histone deacetylase 7

chr15_-_91537724 0.088 NM_003981
NM_199413
NM_199414
PRC1


protein regulator of cytokinesis 1


chr20_-_39928708 0.088 NM_015035
ZHX3
zinc fingers and homeoboxes 3
chr8_+_77593506 0.088 NM_024721
ZFHX4
zinc finger homeobox 4
chr17_+_35294771 0.088 NM_005568
LHX1
LIM homeobox 1
chrX_-_106959597 0.087 NM_001015881
TSC22D3
TSC22 domain family, member 3
chrX_+_49832214 0.087 NM_000084
CLCN5
chloride channel 5
chr8_-_60031545 0.086 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr18_+_77441429 0.086 NM_001202504
CTDP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr5_-_114938060 0.085 NM_021649
TICAM2
toll-like receptor adaptor molecule 2
chr17_+_66508525 0.084 NM_002734
NM_212472
PRKAR1A

protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

chr5_-_171433876 0.084 NM_012300
NM_033644
NM_033645
FBXW11


F-box and WD repeat domain containing 11


chr6_-_153452383 0.084 NM_012419
RGS17
regulator of G-protein signaling 17
chr9_+_91003238 0.083 NM_006717
SPIN1
spindlin 1
chr4_+_1894508 0.083 NM_007331
NM_133330
NM_133331
NM_133335
WHSC1



Wolf-Hirschhorn syndrome candidate 1



chr12_-_104234968 0.083 NM_001031701
NT5DC3
5'-nucleotidase domain containing 3
chr14_-_88789531 0.082 NM_138317
KCNK10
potassium channel, subfamily K, member 10
chr2_+_201170795 0.082 NM_001100422
NM_001100424
NM_001100423
SPATS2L


spermatogenesis associated, serine-rich 2-like


chr10_+_60936346 0.081 NM_032439
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr22_-_36903086 0.081 NM_024955
NM_001102371
FOXRED2

FAD-dependent oxidoreductase domain containing 2

chr2_-_152955208 0.081 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr13_+_109248499 0.080 NM_015011
MYO16
myosin XVI
chrX_+_101967103 0.079 NM_001004051
NM_001184874
NM_001184875
NM_001184876
NM_138437
GPRASP2




G protein-coupled receptor associated sorting protein 2




chr2_-_152955502 0.079 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr13_+_109281569 0.078 NM_001198950
MYO16
myosin XVI
chr3_+_23986735 0.078 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr5_+_89770680 0.078 NM_006467
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr3_-_66550844 0.078 NM_015541
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr12_-_124457099 0.078 NM_025140
CCDC92
coiled-coil domain containing 92
chr6_+_42788793 0.078 NM_015349
KIAA0240
KIAA0240
chr9_-_80646150 0.077 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr9_+_131218678 0.076 NM_153433
NM_153440
ODF2

outer dense fiber of sperm tails 2

chr11_-_47574766 0.076 NM_006560
CELF1
CUGBP, Elav-like family member 1
chr4_+_1873035 0.076 NM_001042424
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr11_+_122526339 0.076 NM_032873
UBASH3B
ubiquitin associated and SH3 domain containing B
chr14_-_91976630 0.076 NM_032560
SMEK1
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr17_+_33914278 0.075 NM_001030006
NM_001282
AP2B1

adaptor-related protein complex 2, beta 1 subunit

chr12_+_26205490 0.075 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr17_+_75446612 0.074 NM_001113496
SEPT9
septin 9
chr22_+_39101806 0.074 NM_004286
GTPBP1
GTP binding protein 1
chr12_-_80307690 0.073 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr15_-_23086842 0.073 NM_001142275
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr5_-_171881421 0.073 NM_001017995
SH3PXD2B
SH3 and PX domains 2B
chr2_-_218808705 0.072 NM_022648
TNS1
tensin 1
chr1_-_27816676 0.072 NM_001201404
NM_006990
WASF2

WAS protein family, member 2

chr6_-_159239269 0.072 NM_003379
EZR
ezrin
chr14_-_103523619 0.072 NM_006035
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr4_+_71768056 0.072 NM_001244766
NM_001244767
NM_173468
MOB1B


MOB kinase activator 1B


chr2_-_167232464 0.072 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr6_-_34664587 0.072 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr7_+_94285620 0.071 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr21_-_32931289 0.071 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr16_-_89007605 0.071 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr11_-_64612040 0.070 NM_017525
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr12_-_49182718 0.070 NM_020983
ADCY6
adenylate cyclase 6
chr18_-_72921280 0.070 NM_175907
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr19_-_33166057 0.070 NM_032139
ANKRD27
ankyrin repeat domain 27 (VPS9 domain)
chr5_-_89770432 0.070 NM_203406
MBLAC2
metallo-beta-lactamase domain containing 2
chr17_-_42908178 0.070 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr10_+_124768401 0.070 NM_001609
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chr18_-_12656730 0.070 NM_001128627
SPIRE1
spire homolog 1 (Drosophila)
chr7_+_36429388 0.070 NM_018685
ANLN
anillin, actin binding protein
chr12_+_110906203 0.070 NM_013300
C12orf24
chromosome 12 open reading frame 24
chr6_+_52226866 0.069 NM_133367
PAQR8
progestin and adipoQ receptor family member VIII
chr11_+_120207617 0.069 NM_001198665
NM_015313
ARHGEF12

Rho guanine nucleotide exchange factor (GEF) 12

chr6_+_108881010 0.069 NM_201559
FOXO3
forkhead box O3
chr17_+_75283972 0.069 NM_001113492
SEPT9
septin 9
chr12_-_31743822 0.068 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr7_+_94285676 0.067 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr3_+_135741576 0.067 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr8_+_37620100 0.066 NM_007198
PROSC
proline synthetase co-transcribed homolog (bacterial)
chr12_-_80329234 0.066 NM_001143885
NM_001244990
PPP1R12A

protein phosphatase 1, regulatory subunit 12A

chr17_-_79828691 0.066 NM_001185077
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr12_-_94853696 0.066 NM_001042399
NM_016122
CCDC41

coiled-coil domain containing 41

chr4_-_140477290 0.066 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr1_-_197169635 0.065 NM_194314
ZBTB41
zinc finger and BTB domain containing 41
chr6_-_52441815 0.065 NM_012288
TRAM2
translocation associated membrane protein 2
chr5_-_114880536 0.065 NM_020177
FEM1C
fem-1 homolog c (C. elegans)
chr1_+_24829299 0.065 NM_001251977
NM_001251981
NM_001251983
NM_013441
RCAN3



RCAN family member 3



chr16_+_1728256 0.065 NM_144570
HN1L
hematological and neurological expressed 1-like
chr2_-_197036301 0.064 NM_004226
STK17B
serine/threonine kinase 17b
chr12_+_26126687 0.064 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr11_+_121163343 0.064 NM_006918
SC5DL
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
chr5_+_72143929 0.063 NM_153188
TNPO1
transportin 1
chr3_+_69812961 0.063 NM_006722
MITF
microphthalmia-associated transcription factor
chr12_+_6961257 0.063 NM_001098536
NM_003481
USP5

ubiquitin specific peptidase 5 (isopeptidase T)

chr9_+_131218279 0.063 NM_001242352
NM_001242353
NM_001242354
NM_002540
NM_153432
NM_153435
NM_153439
ODF2






outer dense fiber of sperm tails 2






chrX_+_49687212 0.062 NM_001127898
NM_001127899
CLCN5

chloride channel 5

chr11_-_47545539 0.062 NM_001172639
CELF1
CUGBP, Elav-like family member 1
chr16_+_12995454 0.062 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr9_-_72374855 0.062 NM_001099666
PTAR1
protein prenyltransferase alpha subunit repeat containing 1
chr6_+_108882068 0.062 NM_001455
FOXO3
forkhead box O3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.86 3.37e-07 GO:0006464 protein modification process
1.79 3.20e-06 GO:0043412 macromolecule modification
1.93 1.51e-05 GO:0035556 intracellular signal transduction
1.30 4.35e-05 GO:0050794 regulation of cellular process
1.28 5.84e-05 GO:0050789 regulation of biological process
3.43 1.38e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.17 1.53e-04 GO:0009987 cellular process
2.01 1.94e-04 GO:0006793 phosphorus metabolic process
2.01 1.94e-04 GO:0006796 phosphate metabolic process
1.25 2.34e-04 GO:0065007 biological regulation
1.46 3.44e-04 GO:0051179 localization
1.55 9.27e-04 GO:0044267 cellular protein metabolic process
3.11 9.31e-04 GO:0030036 actin cytoskeleton organization
1.92 1.31e-03 GO:0032268 regulation of cellular protein metabolic process
2.36 1.68e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.73 2.14e-03 GO:0007399 nervous system development
1.84 4.68e-03 GO:0051246 regulation of protein metabolic process
2.04 5.29e-03 GO:0006468 protein phosphorylation
2.54 5.54e-03 GO:0051056 regulation of small GTPase mediated signal transduction
2.27 1.00e-02 GO:0043549 regulation of kinase activity
2.43 1.30e-02 GO:0007264 small GTPase mediated signal transduction
2.68 1.35e-02 GO:0030029 actin filament-based process
3.81 1.48e-02 GO:0007265 Ras protein signal transduction
2.20 2.15e-02 GO:0051338 regulation of transferase activity
1.39 2.23e-02 GO:0007275 multicellular organismal development
1.37 2.37e-02 GO:0023052 signaling
2.20 2.62e-02 GO:0007010 cytoskeleton organization
2.75 3.21e-02 GO:0046578 regulation of Ras protein signal transduction
1.36 3.26e-02 GO:0032502 developmental process
1.40 4.85e-02 GO:0019538 protein metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 1.39e-06 GO:0005737 cytoplasm
1.16 2.33e-05 GO:0044424 intracellular part
1.63 7.29e-05 GO:0005829 cytosol
1.15 9.52e-05 GO:0005622 intracellular
1.73 1.11e-04 GO:0005856 cytoskeleton
2.54 2.21e-04 GO:0045202 synapse
2.50 4.68e-04 GO:0043005 neuron projection
1.88 2.67e-03 GO:0042995 cell projection
3.08 4.53e-03 GO:0031252 cell leading edge
1.24 9.19e-03 GO:0044444 cytoplasmic part
1.07 1.04e-02 GO:0044464 cell part
1.07 1.05e-02 GO:0005623 cell
1.99 1.17e-02 GO:0030054 cell junction
1.80 1.79e-02 GO:0005626 insoluble fraction
2.78 2.94e-02 GO:0030425 dendrite
9.66 3.29e-02 GO:0034706 sodium channel complex
1.36 3.96e-02 GO:0043234 protein complex
3.79 4.42e-02 GO:0030027 lamellipodium

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.36 6.81e-10 GO:0005515 protein binding
2.53 4.97e-06 GO:0008092 cytoskeletal protein binding
1.14 4.25e-04 GO:0005488 binding
1.92 5.53e-04 GO:0030234 enzyme regulator activity
2.75 9.44e-04 GO:0005083 small GTPase regulator activity
2.01 1.32e-03 GO:0019899 enzyme binding
2.29 2.24e-03 GO:0030695 GTPase regulator activity
2.22 4.00e-03 GO:0060589 nucleoside-triphosphatase regulator activity
2.26 5.12e-03 GO:0019904 protein domain specific binding
2.05 5.39e-03 GO:0004672 protein kinase activity
2.49 5.69e-03 GO:0003779 actin binding
1.88 9.86e-03 GO:0016301 kinase activity
2.21 1.05e-02 GO:0004674 protein serine/threonine kinase activity
1.79 1.35e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.89 1.51e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.56 2.32e-02 GO:0005096 GTPase activator activity
7.56 4.06e-02 GO:0030971 receptor tyrosine kinase binding