Motif ID: UUGGUCC

Z-value: 1.333


Mature miRNA associated with seed UUGGUCC:

NamemiRBase Accession
hsa-miR-133a MIMAT0000427
hsa-miR-133b MIMAT0000770



Activity profile for motif UUGGUCC.

activity profile for motif UUGGUCC


Sorted Z-values histogram for motif UUGGUCC

Sorted Z-values for motif UUGGUCC



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGUCC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_48937795 3.342 NM_000138
FBN1
fibrillin 1
chr2_+_33359607 2.189 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr2_+_33172368 2.160 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr8_-_38325241 1.888 NM_001174065
NM_001174066
NM_001174067
FGFR1


fibroblast growth factor receptor 1


chr8_-_38326351 1.849 NM_001174063
NM_001174064
NM_015850
NM_023105
NM_023106
NM_023110
FGFR1





fibroblast growth factor receptor 1





chr13_-_33760215 1.678 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr13_-_33780142 1.601 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr13_-_33859835 1.561 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_-_52441815 1.520 NM_012288
TRAM2
translocation associated membrane protein 2
chr6_+_72926462 1.467 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr6_-_132272311 1.461 NM_001901
CTGF
connective tissue growth factor
chr1_+_170633312 1.458 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr6_+_72922513 1.401 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr4_-_39640461 1.369 NM_174921
C4orf34
chromosome 4 open reading frame 34
chr8_+_17354562 1.366 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr6_+_72926144 1.306 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr6_+_73076431 1.178 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr10_-_21463019 1.168 NM_001173484
NM_213569
NEBL

nebulette

chr17_-_43045612 1.118 NM_006688
C1QL1
complement component 1, q subcomponent-like 1
chrX_+_9431314 1.110 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr8_+_17396285 1.102 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr16_+_29823408 1.097 NM_145239
PRRT2
proline-rich transmembrane protein 2
chrX_+_9432980 1.069 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr9_-_20622476 1.061 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr10_-_79397546 1.054 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr10_+_60272868 1.026 NM_001080512
BICC1
bicaudal C homolog 1 (Drosophila)
chr17_-_48278987 1.016 NM_000088
COL1A1
collagen, type I, alpha 1
chr12_-_63328663 1.014 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr1_-_149889362 1.001 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chr14_-_89883306 0.861 NM_005197
FOXN3
forkhead box N3
chr10_-_21186530 0.851 NM_006393
NEBL
nebulette
chr20_-_39928708 0.844 NM_015035
ZHX3
zinc fingers and homeoboxes 3
chr5_-_127873734 0.775 NM_001999
FBN2
fibrillin 2
chr11_+_76777926 0.770 NM_004055
CAPN5
calpain 5
chr8_-_93029864 0.758 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr14_-_90085325 0.723 NM_001085471
FOXN3
forkhead box N3
chr8_-_93115453 0.721 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr3_+_141043054 0.681 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr7_+_102073953 0.670 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr2_-_238322840 0.663 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr12_+_79257772 0.658 NM_001135805
SYT1
synaptotagmin I
chr6_+_72596648 0.642 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr8_-_93111915 0.637 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_-_15900928 0.610 NM_015199
ANKRD28
ankyrin repeat domain 28
chr12_+_79439432 0.606 NM_001135806
SYT1
synaptotagmin I
chr6_+_11538486 0.596 NM_001100829
TMEM170B
transmembrane protein 170B
chr8_-_93107442 0.593 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr2_+_191745546 0.589 NM_014905
GLS
glutaminase
chr8_-_93107881 0.587 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr1_+_97187174 0.580 NM_021190
PTBP2
polypyrimidine tract binding protein 2
chr5_+_118407067 0.569 NM_005509
DMXL1
Dmx-like 1
chr20_-_30310597 0.567 NM_001191
NM_138578
BCL2L1

BCL2-like 1

chr12_+_79258448 0.554 NM_005639
SYT1
synaptotagmin I
chr17_-_33390676 0.540 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr1_+_109102970 0.540 NM_001010883
FAM102B
family with sequence similarity 102, member B
chr20_+_11898536 0.539 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr1_-_208417635 0.537 NM_025179
PLXNA2
plexin A2
chr3_-_15798057 0.536 NM_001195099
ANKRD28
ankyrin repeat domain 28
chr11_+_12695851 0.530 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr19_-_7293876 0.527 NM_000208
NM_001079817
INSR

insulin receptor

chr4_-_89618928 0.523 NM_153757
NAP1L5
nucleosome assembly protein 1-like 5
chr12_+_15699277 0.521 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chr1_-_159895279 0.496 NM_003564
TAGLN2
transgelin 2
chr8_+_104383785 0.491 NM_138455
CTHRC1
collagen triple helix repeat containing 1
chr15_-_37390372 0.481 NM_172315
MEIS2
Meis homeobox 2
chr8_+_22409226 0.478 NM_005775
SORBS3
sorbin and SH3 domain containing 3
chr16_+_50775960 0.468 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr20_+_56964162 0.462 NM_001195677
NM_004738
VAPB

VAMP (vesicle-associated membrane protein)-associated protein B and C

chr2_-_85555343 0.460 NM_001206840
NM_001206841
NM_001206844
NM_006464
TGOLN2



trans-golgi network protein 2



chr3_-_179169330 0.456 NM_021629
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr11_-_61584451 0.454 NM_013402
FADS1
fatty acid desaturase 1
chr5_+_75699003 0.454 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr14_+_75898836 0.452 NM_001135049
JDP2
Jun dimerization protein 2
chr5_-_65017874 0.452 NM_019072
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chrX_-_77041678 0.450 NM_000489
NM_138270
ATRX

alpha thalassemia/mental retardation syndrome X-linked

chr21_+_44394634 0.443 NM_004571
PKNOX1
PBX/knotted 1 homeobox 1
chr12_-_49182718 0.443 NM_020983
ADCY6
adenylate cyclase 6
chr20_-_3149070 0.443 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr6_+_24495166 0.435 NM_001080
NM_170740
ALDH5A1

aldehyde dehydrogenase 5 family, member A1

chr4_-_7941092 0.432 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr20_+_11871364 0.432 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr14_+_75894919 0.430 NM_001135048
NM_130469
JDP2

Jun dimerization protein 2

chr14_+_75894508 0.428 NM_001135047
JDP2
Jun dimerization protein 2
chr3_-_15839674 0.426 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr1_+_78245306 0.425 NM_198549
FAM73A
family with sequence similarity 73, member A
chr2_-_198175494 0.422 NM_001195144
NM_153697
ANKRD44

ankyrin repeat domain 44

chr4_+_113970784 0.421 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr17_+_21279667 0.420 NM_021012
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr16_+_50776012 0.420 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr8_-_93075190 0.416 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr16_-_1429612 0.404 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr3_-_196695608 0.401 NM_025163
PIGZ
phosphatidylinositol glycan anchor biosynthesis, class Z
chr5_-_172198160 0.398 NM_004417
DUSP1
dual specificity phosphatase 1
chr17_+_61699786 0.394 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr1_+_11866206 0.391 NM_001286
NM_021735
NM_021736
NM_021737
CLCN6



chloride channel 6



chr6_-_52926588 0.389 NM_014920
NM_016513
ICK

intestinal cell (MAK-like) kinase

chr4_+_113739203 0.388 NM_001127493
ANK2
ankyrin 2, neuronal
chr10_-_104473957 0.387 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr4_+_26321307 0.383 NM_005349
NM_203283
RBPJ

recombination signal binding protein for immunoglobulin kappa J region

chr1_+_20878931 0.383 NM_207334
FAM43B
family with sequence similarity 43, member B
chr16_+_88493878 0.382 NM_001127464
ZNF469
zinc finger protein 469
chr12_+_15475190 0.376 NM_002848
NM_030667
PTPRO

protein tyrosine phosphatase, receptor type, O

chr9_-_21335239 0.371 NM_018847
KLHL9
kelch-like 9 (Drosophila)
chr17_-_53809444 0.367 NM_001099640
TMEM100
transmembrane protein 100
chr17_-_36956145 0.362 NM_003559
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr17_-_53800074 0.358 NM_018286
TMEM100
transmembrane protein 100
chr5_-_171881421 0.356 NM_001017995
SH3PXD2B
SH3 and PX domains 2B
chr4_+_37246689 0.355 NM_001144990
KIAA1239
KIAA1239
chr8_+_22423170 0.352 NM_001018003
SORBS3
sorbin and SH3 domain containing 3
chr12_+_51818592 0.351 NM_001039960
NM_004858
SLC4A8

solute carrier family 4, sodium bicarbonate cotransporter, member 8

chr1_-_36184727 0.351 NM_152374
C1orf216
chromosome 1 open reading frame 216
chr16_-_67184822 0.351 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr4_+_6784453 0.347 NM_001100590
NM_014743
KIAA0232

KIAA0232

chrX_-_140271293 0.346 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr9_+_91606349 0.345 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chr7_+_100728719 0.344 NM_030961
TRIM56
tripartite motif containing 56
chr12_-_105629790 0.340 NM_001251904
NM_018171
APPL2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr15_-_37393364 0.337 NM_001220482
NM_002399
MEIS2

Meis homeobox 2

chr5_-_178157597 0.335 NM_005649
ZNF354A
zinc finger protein 354A
chr12_-_109125289 0.332 NM_014325
CORO1C
coronin, actin binding protein, 1C
chr17_-_27045172 0.331 NM_001142624
NM_001142625
NM_001144943
RAB34


RAB34, member RAS oncogene family


chr7_+_28725597 0.327 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr20_-_35488275 0.326 NM_199181
KIAA0889
KIAA0889
chr2_-_145277879 0.324 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr1_-_149900143 0.323 NM_005850
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr16_-_15736964 0.318 NM_001184998
NM_001184999
NM_014647
KIAA0430


KIAA0430


chr11_-_9025531 0.318 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr7_-_28220342 0.317 NM_175061
JAZF1
JAZF zinc finger 1
chr7_+_28475233 0.313 NM_004904
CREB5
cAMP responsive element binding protein 5
chr18_+_9137560 0.311 NM_001204056
ANKRD12
ankyrin repeat domain 12
chr16_-_31106125 0.311 NM_024006
NM_206824
VKORC1

vitamin K epoxide reductase complex, subunit 1

chr4_-_96470350 0.311 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chr11_-_82782883 0.308 NM_014488
RAB30
RAB30, member RAS oncogene family
chr6_+_36410543 0.308 NM_173562
KCTD20
potassium channel tetramerisation domain containing 20
chr15_+_41523401 0.306 NM_007236
CHP
calcium binding protein P22
chr8_+_81398416 0.304 NM_001105539
NM_023929
ZBTB10

zinc finger and BTB domain containing 10

chr16_-_66584045 0.304 NM_001172643
NM_001172644
NM_001172645
NM_004614
TK2



thymidine kinase 2, mitochondrial



chr22_-_24640850 0.301 NM_001099781
NM_001099782
NM_004121
GGT5


gamma-glutamyltransferase 5


chr13_-_40177355 0.300 NM_005780
LHFP
lipoma HMGIC fusion partner
chr15_-_37392358 0.296 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chr16_+_30406711 0.296 NM_152652
ZNF48
zinc finger protein 48
chr9_+_2015218 0.292 NM_003070
NM_139045
SMARCA2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr18_+_9136742 0.290 NM_001083625
NM_015208
ANKRD12

ankyrin repeat domain 12

chr20_-_3388219 0.286 NM_001009984
C20orf194
chromosome 20 open reading frame 194
chr12_-_49177876 0.282 NM_015270
ADCY6
adenylate cyclase 6
chr17_-_27044728 0.279 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr1_-_35370983 0.275 NM_001080418
DLGAP3
discs, large (Drosophila) homolog-associated protein 3
chrX_-_48900932 0.274 NM_006521
TFE3
transcription factor binding to IGHM enhancer 3
chr7_+_44084238 0.273 NM_001014436
NM_001122956
NM_014063
DBNL


drebrin-like


chrX_+_153665258 0.263 NM_001493
GDI1
GDP dissociation inhibitor 1
chr10_+_116581495 0.258 NM_001135051
NM_020940
FAM160B1

family with sequence similarity 160, member B1

chr22_-_17602142 0.254 NM_031890
NM_001163079
CECR6

cat eye syndrome chromosome region, candidate 6

chr2_-_179343225 0.254 NM_001135212
NM_181342
FKBP7

FK506 binding protein 7

chr16_+_23568833 0.252 NM_019116
UBFD1
ubiquitin family domain containing 1
chr1_-_183604885 0.252 NM_005717
ARPC5
actin related protein 2/3 complex, subunit 5, 16kDa
chr7_-_152133071 0.250 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr22_-_41842853 0.250 NM_016272
TOB2
transducer of ERBB2, 2
chr4_-_114900802 0.244 NM_024590
ARSJ
arylsulfatase family, member J
chr5_+_140718353 0.240 NM_018915
NM_032009
PCDHGA2

protocadherin gamma subfamily A, 2

chr11_+_12399024 0.240 NM_018222
PARVA
parvin, alpha
chr17_-_8066254 0.240 NM_014232
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr5_+_140729723 0.239 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr5_+_140753480 0.238 NM_018919
NM_032086
PCDHGA6

protocadherin gamma subfamily A, 6

chr15_-_37391596 0.237 NM_172316
MEIS2
Meis homeobox 2
chr16_+_30389632 0.231 NM_001214906
NM_001214907
ZNF48

zinc finger protein 48

chrX_-_119709618 0.231 NM_003588
CUL4B
cullin 4B
chr5_+_140749830 0.228 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr8_-_23021447 0.225 NM_003840
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr12_-_82153092 0.225 NM_003625
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr1_-_155532322 0.224 NM_018489
ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr5_-_133561805 0.224 NM_002715
PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
chrX_+_103411065 0.223 NM_207318
FAM199X
family with sequence similarity 199, X-linked
chr6_+_42952328 0.223 NM_006245
NM_180976
NM_180977
PPP2R5D


protein phosphatase 2, regulatory subunit B', delta


chr11_+_64794879 0.218 NM_013306
NM_147777
SNX15

sorting nexin 15

chr1_+_118148506 0.216 NM_017709
FAM46C
family with sequence similarity 46, member C
chr5_+_140739589 0.215 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr6_+_160182988 0.214 NM_005891
ACAT2
acetyl-CoA acetyltransferase 2
chr17_+_37026111 0.214 NM_006148
LASP1
LIM and SH3 protein 1
chr3_-_39234071 0.211 NM_194293
NM_001198621
XIRP1

xin actin-binding repeat containing 1

chr7_+_55433140 0.210 NM_018697
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr1_+_47799447 0.209 NM_001136140
NM_016308
CMPK1

cytidine monophosphate (UMP-CMP) kinase 1, cytosolic

chr2_-_27485774 0.208 NM_003459
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr7_-_100286869 0.208 NM_022574
GIGYF1
GRB10 interacting GYF protein 1
chr17_+_38296506 0.207 NM_007359
CASC3
cancer susceptibility candidate 3
chr1_+_101361589 0.207 NM_001144884
NM_133496
SLC30A7

solute carrier family 30 (zinc transporter), member 7

chr11_+_120110902 0.205 NM_014352
POU2F3
POU class 2 homeobox 3
chr16_+_68573660 0.205 NM_133458
ZFP90
zinc finger protein 90 homolog (mouse)
chr17_+_27717942 0.204 NM_020791
NM_025142
TAOK1

TAO kinase 1

chr3_-_53916199 0.202 NM_022899
ACTR8
ARP8 actin-related protein 8 homolog (yeast)
chr5_+_140723600 0.200 NM_018916
NM_032011
PCDHGA3

protocadherin gamma subfamily A, 3

chr20_+_23345020 0.198 NM_022482
GZF1
GDNF-inducible zinc finger protein 1
chr17_+_5031686 0.198 NM_004505
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr5_+_154092461 0.198 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr5_+_140792507 0.197 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr17_+_73043154 0.197 NM_015353
KCTD2
potassium channel tetramerisation domain containing 2
chr4_+_26322184 0.197 NM_015874
NM_203284
RBPJ

recombination signal binding protein for immunoglobulin kappa J region

chr5_+_175665337 0.196 NM_198567
C5orf25
chromosome 5 open reading frame 25
chr8_-_23712297 0.196 NM_003155
STC1
stanniocalcin 1
chr7_+_28338939 0.196 NM_182899
CREB5
cAMP responsive element binding protein 5
chr19_+_16178170 0.193 NM_001145160
TPM4
tropomyosin 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
5.92 2.67e-08 GO:0007156 homophilic cell adhesion
3.54 1.15e-05 GO:0016337 cell-cell adhesion
2.17 3.57e-03 GO:0007155 cell adhesion
2.17 3.57e-03 GO:0022610 biological adhesion
35.26 3.54e-02 GO:0035581 extracellular sequestering of receptor ligand
35.26 3.54e-02 GO:0035583 negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta
35.26 3.54e-02 GO:0071692 protein localization in extracellular region
35.26 3.54e-02 GO:0071694 maintenance of protein location in extracellular region

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.25 5.30e-04 GO:0005509 calcium ion binding