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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: YY1.p2

Z-value: 2.521

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_+_102104941	1.351	NM_004791	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)
chr4_+_126237566	1.116	NM_024582	FAT4	FAT tumor suppressor homolog 4 (Drosophila)
chr5_-_41510627	1.081	NM_001005473	PLCXD3	phosphatidylinositol-specific phospholipase C, X domain containing 3
chr2_-_158300517	0.897	NM_004288	CYTIP	cytohesin 1 interacting protein
chr17_+_26369617	0.886	NM_016231	NLK	nemo-like kinase
chr12_+_56075418	0.870		METTL7B	methyltransferase like 7B
chr12_+_94071150	0.863	NM_003805	CRADD	CASP2 and RIPK1 domain containing adaptor with death domain
chr12_+_56075329	0.844	NM_152637	METTL7B	methyltransferase like 7B
chr1_-_161102457	0.824	NM_001039711 NM_032998	DEDD	death effector domain containing
chr20_-_3765747	0.811		CENPB	centromere protein B, 80kDa
chr17_-_1303402	0.784		YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr14_+_29236882	0.741		FOXG1	forkhead box G1
chr1_-_161102367	0.727		DEDD	death effector domain containing
chr1_+_155829259	0.710	NM_152280	SYT11	synaptotagmin XI
chr4_+_113970784	0.698	NM_001148 NM_020977	ANK2	ankyrin 2, neuronal
chr11_+_122526339	0.652	NM_032873	UBASH3B	ubiquitin associated and SH3 domain containing B
chr19_+_5623119	0.649		SAFB	scaffold attachment factor B
chr17_-_48264039	0.646		COL1A1	collagen, type I, alpha 1
chr14_-_53417272	0.640		FERMT2	fermitin family member 2
chr5_+_159343739	0.629	NM_000679	ADRA1B	adrenergic, alpha-1B-, receptor
chr21_+_47545896	0.616		COL6A2	collagen, type VI, alpha 2
chr17_-_28618836	0.613		BLMH	bleomycin hydrolase
chr12_-_108954942	0.613		SART3	squamous cell carcinoma antigen recognized by T cells 3
chr10_-_61666184	0.611		CCDC6	coiled-coil domain containing 6
chr12_-_108954952	0.610		SART3	squamous cell carcinoma antigen recognized by T cells 3
chr1_+_51435911	0.590		CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr14_-_60337350	0.589	NM_021136	RTN1	reticulon 1
chr15_+_91769329	0.588		SV2B	synaptic vesicle glycoprotein 2B
chr5_-_137089434	0.588		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr1_-_149899623	0.581		SF3B4	splicing factor 3b, subunit 4, 49kDa
chr11_+_69455978	0.580		CCND1	cyclin D1
chr7_-_23509631	0.576
chr12_-_6665220	0.560	NM_001039670 NM_001193457 NM_080730	IFFO1	intermediate filament family orphan 1
chr17_-_28619183	0.552	NM_000386	BLMH	bleomycin hydrolase
chr16_-_67260720	0.533	NM_012163	LRRC29	leucine rich repeat containing 29
chr5_+_71403040	0.533	NM_005909	MAP1B	microtubule-associated protein 1B
chr14_-_92413738	0.521		FBLN5	fibulin 5
chr13_-_95364248	0.519	NM_007084	SOX21	SRY (sex determining region Y)-box 21
chr14_-_23503924	0.516		PSMB5	proteasome (prosome, macropain) subunit, beta type, 5
chr11_+_15133969	0.513	NM_001031853	INSC	inscuteable homolog (Drosophila)
chr16_-_30006911	0.511		HIRIP3	HIRA interacting protein 3
chr8_-_121824015	0.508
chr17_-_8066254	0.505	NM_014232	VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)
chr1_+_51435641	0.502	NM_078626	CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr19_+_507475	0.499	NM_033513	TPGS1	tubulin polyglutamylase complex subunit 1
chr1_-_150849062	0.495		ARNT	aryl hydrocarbon receptor nuclear translocator
chr2_-_40657419	0.492	NM_001112800 NM_001112801 NM_001252624 NM_021097	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1
chr14_-_23504353	0.491	NM_001144932 NM_002797 NM_001130725	PSMB5	proteasome (prosome, macropain) subunit, beta type, 5
chr10_+_105005643	0.491	NM_001143909	LOC729020	rcRPE
chr2_+_149402559	0.487	NM_015630	EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr7_+_150065968	0.487		REPIN1	replication initiator 1
chr19_+_49468656	0.484		FTL	ferritin, light polypeptide
chr10_+_31608097	0.483	NM_001174093 NM_001174095 NM_001174096 NM_030751	ZEB1	zinc finger E-box binding homeobox 1
chr22_+_21271940	0.479		CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr17_+_26369935	0.472		NLK	nemo-like kinase
chr4_+_114214102	0.471		ANK2	ankyrin 2, neuronal
chrX_-_153285262	0.467		IRAK1	interleukin-1 receptor-associated kinase 1
chr12_+_32654976	0.465	NM_139241	FGD4	FYVE, RhoGEF and PH domain containing 4
chr7_-_72971868	0.464		BCL7B	B-cell CLL/lymphoma 7B
chr20_-_50179338	0.464		NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr15_-_89764809	0.463	NM_000326	RLBP1	retinaldehyde binding protein 1
chr5_-_172198160	0.462	NM_004417	DUSP1	dual specificity phosphatase 1
chr14_-_61115906	0.459	NM_005982	SIX1	SIX homeobox 1
chr19_+_49468587	0.457		FTL	ferritin, light polypeptide
chr14_-_53417636	0.457		FERMT2	fermitin family member 2
chr19_-_5622725	0.456		SAFB2	scaffold attachment factor B2
chr2_-_190044330	0.451	NM_000393	COL5A2	collagen, type V, alpha 2
chr1_+_162467622	0.451		UHMK1	U2AF homology motif (UHM) kinase 1
chr7_-_72972021	0.449	NM_001197244 NM_001707	BCL7B	B-cell CLL/lymphoma 7B
chr22_-_24110054	0.449	NM_213720	CHCHD10	coiled-coil-helix-coiled-coil-helix domain containing 10
chr15_+_93443559	0.448		CHD2	chromodomain helicase DNA binding protein 2
chr1_+_114522029	0.436	NM_020190	OLFML3	olfactomedin-like 3
chr19_+_10812111	0.434	NM_031209	QTRT1	queuine tRNA-ribosyltransferase 1
chr6_+_26045611	0.430	NM_003531	HIST1H3C	histone cluster 1, H3c
chr19_-_2456954	0.429	NM_032737	LMNB2	lamin B2
chr1_-_86043932	0.428	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr1_+_78444922	0.426		DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr19_+_49468557	0.426	NM_000146	FTL	ferritin, light polypeptide
chr17_-_1303548	0.426	NM_006761	YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr21_-_39288661	0.424	NM_002240	KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6
chr5_-_172755195	0.420		STC2	stanniocalcin 2
chr8_-_30585220	0.419		GSR	glutathione reductase
chr17_+_38599651	0.419	NM_001552	IGFBP4	insulin-like growth factor binding protein 4
chr1_-_149900143	0.418	NM_005850	SF3B4	splicing factor 3b, subunit 4, 49kDa
chr1_-_161102210	0.413	NM_001039712	DEDD	death effector domain containing
chr7_-_72936538	0.413		BAZ1B	bromodomain adjacent to zinc finger domain, 1B
chr10_-_79397204	0.411		KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr11_-_65686439	0.409	NM_001135635 NM_031450	C11orf68	chromosome 11 open reading frame 68
chr19_-_39340609	0.407	NM_001533	HNRNPL	heterogeneous nuclear ribonucleoprotein L
chr5_+_137801166	0.406		EGR1	early growth response 1
chr11_+_5474637	0.403	NM_001004754	OR51I2	olfactory receptor, family 51, subfamily I, member 2
chr14_-_20774129	0.402	NM_138376	TTC5	tetratricopeptide repeat domain 5
chr3_+_128199744	0.401
chr1_-_78444690	0.400		FUBP1	far upstream element (FUSE) binding protein 1
chr19_+_46850245	0.399	NM_001204284 NM_006247	PPP5C	protein phosphatase 5, catalytic subunit
chr15_-_53082087	0.399	NM_004498	ONECUT1	one cut homeobox 1
chr11_+_69455837	0.396	NM_053056	CCND1	cyclin D1
chr10_+_86131546	0.396		FAM190B	family with sequence similarity 190, member B
chr19_-_39322411	0.396	NM_001398	ECH1	enoyl CoA hydratase 1, peroxisomal
chr19_+_5623143	0.395		SAFB	scaffold attachment factor B
chr17_-_80041166	0.393		FASN	fatty acid synthase
chr2_+_149402321	0.386		EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr2_+_178257488	0.386		AGPS	alkylglycerone phosphate synthase
chr13_+_44947977	0.385	NM_001010897	SERP2	stress-associated endoplasmic reticulum protein family member 2
chr11_-_111749810	0.384		FDXACB1	ferredoxin-fold anticodon binding domain containing 1
chr1_-_85930733	0.382	NM_012137	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr19_+_5623045	0.382	NM_001201338 NM_001201339 NM_001201340 NM_002967	SAFB	scaffold attachment factor B
chr19_-_39340548	0.382		HNRNPL	heterogeneous nuclear ribonucleoprotein L
chrX_+_100333835	0.381	NM_021637	TMEM35	transmembrane protein 35
chr7_-_139477437	0.380	NM_001113239 NM_022740	HIPK2	homeodomain interacting protein kinase 2
chr4_-_6911373	0.379
chr1_-_150601911	0.376		ENSA	endosulfine alpha
chr9_+_131218402	0.373		ODF2	outer dense fiber of sperm tails 2
chr1_-_183622447	0.372	NM_203454	APOBEC4	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr1_-_150849147	0.370		ARNT	aryl hydrocarbon receptor nuclear translocator
chr1_+_145487301	0.369		LIX1L	Lix1 homolog (mouse)-like
chr7_-_132192837	0.366		PLXNA4	plexin A4
chr16_+_21689834	0.365	NM_144672	OTOA	otoancorin
chr1_-_150602020	0.365		ENSA	endosulfine alpha
chr15_-_90347173	0.365		ANPEP	alanyl (membrane) aminopeptidase
chr12_+_56862300	0.364	NM_207344	SPRYD4	SPRY domain containing 4
chr11_+_69455938	0.364		CCND1	cyclin D1
chr6_-_33168438	0.364		RXRB	retinoid X receptor, beta
chr16_+_86600856	0.363	NM_005251	FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr6_-_34360310	0.362		NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr1_-_232651227	0.361	NM_020808	SIPA1L2	signal-induced proliferation-associated 1 like 2
chrX_-_153285334	0.359	NM_001025242 NM_001025243 NM_001569	IRAK1	interleukin-1 receptor-associated kinase 1
chr5_+_139060295	0.358		CXXC5	CXXC finger protein 5
chr6_+_108882104	0.357		FOXO3	forkhead box O3
chr18_+_72998258	0.357		TSHZ1	teashirt zinc finger homeobox 1
chr19_+_34663414	0.357		LSM14A	LSM14A, SCD6 homolog A (S. cerevisiae)
chr2_-_172016904	0.355		TLK1	tousled-like kinase 1
chr7_+_44144002	0.354		AEBP1	AE binding protein 1
chr1_+_41157493	0.354		NFYC	nuclear transcription factor Y, gamma
chr5_-_137089754	0.354		HNRNPA0	heterogeneous nuclear ribonucleoprotein A0
chr10_-_32345123	0.352		KIF5B	kinesin family member 5B
chr3_+_45636176	0.351	NM_014240	LIMD1	LIM domains containing 1
chr1_+_145472454	0.350		ANKRD34A	ankyrin repeat domain 34A
chr19_+_39390570	0.349		NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr1_-_150602089	0.349	NM_004436 NM_207042 NM_207043 NM_207044 NM_207168	ENSA	endosulfine alpha
chr15_-_25684059	0.348		UBE3A	ubiquitin protein ligase E3A
chr1_-_150849043	0.348		ARNT	aryl hydrocarbon receptor nuclear translocator
chr1_-_85930610	0.345		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr4_+_100871625	0.344		LOC256880	uncharacterized LOC256880
chr11_-_9225780	0.343		DENND5A	DENN/MADD domain containing 5A
chr1_+_41157646	0.343	NM_001142590	NFYC	nuclear transcription factor Y, gamma
chr1_-_12908141	0.343	NM_001146181	HNRNPCL1 LOC649330	heterogeneous nuclear ribonucleoprotein C-like 1 heterogeneous nuclear ribonucleoprotein C-like
chr22_-_17073440	0.340	NM_014406	CCT8L2	chaperonin containing TCP1, subunit 8 (theta)-like 2
chr20_+_44657812	0.339	NM_020708	SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5
chr12_-_108954929	0.338		SART3	squamous cell carcinoma antigen recognized by T cells 3
chr14_+_50360359	0.337		ARF6	ADP-ribosylation factor 6
chr14_-_57735527	0.336		EXOC5	exocyst complex component 5
chr16_+_88493878	0.336	NM_001127464	ZNF469	zinc finger protein 469
chrX_+_152770083	0.334		BGN	biglycan
chr6_+_43139201	0.333		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr11_-_74109417	0.331	NM_173582	PGM2L1	phosphoglucomutase 2-like 1
chr17_-_41856180	0.331	NM_004090	DUSP3	dual specificity phosphatase 3
chr9_+_131218426	0.331		ODF2	outer dense fiber of sperm tails 2
chr6_-_34360098	0.330		NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr11_+_65658101	0.328		CCDC85B	coiled-coil domain containing 85B
chr20_-_34243118	0.326		RBM12	RNA binding motif protein 12
chr12_+_96252705	0.325	NM_003095	SNRPF	small nuclear ribonucleoprotein polypeptide F
chr9_+_131218435	0.325		ODF2	outer dense fiber of sperm tails 2
chr19_+_10531128	0.324	NM_001111307	PDE4A	phosphodiesterase 4A, cAMP-specific
chr10_-_31607919	0.321		ZEB1-AS1	ZEB1 antisense RNA 1 (non-protein coding)
chr1_-_150602047	0.319		ENSA	endosulfine alpha
chr6_-_26189303	0.318	NM_003539	HIST1H4D	histone cluster 1, H4d
chr9_+_131218279	0.318	NM_001242352 NM_001242353 NM_001242354 NM_002540 NM_153432 NM_153435 NM_153439	ODF2	outer dense fiber of sperm tails 2
chr1_+_16693582	0.317	NM_001114600 NM_015609	C1orf144	chromosome 1 open reading frame 144
chr5_-_179044835	0.317		HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)
chr19_+_49376488	0.317		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr7_+_103969103	0.315	NM_199000	LHFPL3	lipoma HMGIC fusion partner-like 3
chr12_+_122459791	0.314	NM_001024808 NM_020993	BCL7A	B-cell CLL/lymphoma 7A
chr19_+_14138959	0.313	NM_080864	RLN3	relaxin 3
chr15_-_90347534	0.310		ANPEP	alanyl (membrane) aminopeptidase
chr19_-_39340362	0.310		HNRNPL	heterogeneous nuclear ribonucleoprotein L
chr19_-_50413063	0.308		NUP62	nucleoporin 62kDa
chr3_-_42917191	0.305		CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1
chr9_+_131218678	0.304	NM_153433 NM_153440	ODF2	outer dense fiber of sperm tails 2
chr13_-_37679800	0.304	NM_145203	CSNK1A1L	casein kinase 1, alpha 1-like
chr17_+_3118911	0.302	NM_014565	OR1A1	olfactory receptor, family 1, subfamily A, member 1
chr12_+_120972155	0.301		RNF10	ring finger protein 10
chr2_-_131099621	0.301	NM_032357	CCDC115	coiled-coil domain containing 115
chr8_-_108510094	0.300	NM_001146 NM_001199859	ANGPT1	angiopoietin 1
chr19_+_16059817	0.300	NM_001004465	OR10H4	olfactory receptor, family 10, subfamily H, member 4
chr5_+_137801178	0.300	NM_001964	EGR1	early growth response 1
chr1_+_203764802	0.299		ZC3H11A	zinc finger CCCH-type containing 11A
chr12_-_29936685	0.297	NM_001193451	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr7_+_35840595	0.297	NM_001011553 NM_001242956 NM_001788	SEPT7	septin 7
chr12_-_49960221	0.297	NM_001012300	MCRS1	microspherule protein 1
chr14_+_55168831	0.296		SAMD4A	sterile alpha motif domain containing 4A
chr1_+_162467635	0.295		UHMK1	U2AF homology motif (UHM) kinase 1
chr15_+_44719765	0.295		CTDSPL2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr8_-_30585442	0.294	NM_000637 NM_001195102 NM_001195103 NM_001195104	GSR	glutathione reductase
chr9_-_130829598	0.294	NM_197956	NAIF1	nuclear apoptosis inducing factor 1
chr3_+_73045939	0.294		PPP4R2	protein phosphatase 4, regulatory subunit 2
chr9_+_140119643	0.292	NM_199001	C9orf169	chromosome 9 open reading frame 169
chr17_-_42275425	0.292	NM_001098833 NM_020218	ATXN7L3	ataxin 7-like 3
chr5_-_133747520	0.292		CDKN2AIPNL	CDKN2A interacting protein N-terminal like
chrX_+_78426468	0.290	NM_032553	GPR174	G protein-coupled receptor 174

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.23	1.09e-39	GO:0044237	cellular metabolic process
1.28	4.76e-34	GO:0044260	cellular macromolecule metabolic process
1.11	2.05e-32	GO:0009987	cellular process
1.35	1.00e-30	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18	1.78e-29	GO:0008152	metabolic process
1.31	7.61e-29	GO:0034641	cellular nitrogen compound metabolic process
1.38	3.27e-27	GO:0090304	nucleic acid metabolic process
1.30	1.58e-26	GO:0006807	nitrogen compound metabolic process
1.19	3.85e-26	GO:0044238	primary metabolic process
1.22	2.06e-25	GO:0043170	macromolecule metabolic process
1.40	3.38e-24	GO:0010467	gene expression
1.40	1.13e-22	GO:0016070	RNA metabolic process
1.69	1.51e-18	GO:0016071	mRNA metabolic process
1.36	1.50e-16	GO:0006996	organelle organization
1.59	1.96e-16	GO:0006396	RNA processing
1.27	4.87e-15	GO:0044267	cellular protein metabolic process
1.24	1.39e-13	GO:0071841	cellular component organization or biogenesis at cellular level
1.70	2.28e-13	GO:0006397	mRNA processing
1.21	4.00e-13	GO:0071840	cellular component organization or biogenesis
1.21	1.54e-12	GO:0016043	cellular component organization
1.24	2.60e-12	GO:0071842	cellular component organization at cellular level
1.44	5.74e-12	GO:0015031	protein transport
1.43	1.99e-11	GO:0045184	establishment of protein localization
1.73	2.89e-11	GO:0008380	RNA splicing
1.72	3.54e-11	GO:0006412	translation
1.36	6.89e-11	GO:0044248	cellular catabolic process
1.49	2.09e-10	GO:0051276	chromosome organization
1.37	2.69e-10	GO:0008104	protein localization
1.20	1.58e-09	GO:0019538	protein metabolic process
1.36	2.81e-09	GO:0007049	cell cycle
1.53	5.87e-09	GO:0006325	chromatin organization
1.47	1.21e-08	GO:0000278	mitotic cell cycle
1.55	1.70e-08	GO:0016032	viral reproduction
1.48	4.91e-08	GO:0044265	cellular macromolecule catabolic process
1.36	5.68e-08	GO:0010605	negative regulation of macromolecule metabolic process
1.77	5.90e-08	GO:0000375	RNA splicing, via transesterification reactions
1.27	1.40e-07	GO:0009056	catabolic process
1.77	1.51e-07	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.77	1.51e-07	GO:0000398	nuclear mRNA splicing, via spliceosome
1.20	2.29e-07	GO:0044249	cellular biosynthetic process
1.25	2.59e-07	GO:0034645	cellular macromolecule biosynthetic process
1.25	2.61e-07	GO:0009059	macromolecule biosynthetic process
1.37	3.14e-07	GO:0022402	cell cycle process
1.46	4.84e-07	GO:0006974	response to DNA damage stimulus
1.19	1.21e-06	GO:0009058	biosynthetic process
1.54	1.31e-06	GO:0044419	interspecies interaction between organisms
1.38	1.59e-06	GO:0022403	cell cycle phase
1.33	1.64e-06	GO:0031324	negative regulation of cellular metabolic process
1.35	1.71e-06	GO:0033554	cellular response to stress
1.27	1.90e-06	GO:0033036	macromolecule localization
1.31	2.55e-06	GO:0009892	negative regulation of metabolic process
1.52	3.48e-06	GO:0016568	chromatin modification
1.39	5.46e-06	GO:0009057	macromolecule catabolic process
1.44	5.56e-06	GO:0034621	cellular macromolecular complex subunit organization
1.53	1.06e-05	GO:0043632	modification-dependent macromolecule catabolic process
2.02	1.26e-05	GO:0031397	negative regulation of protein ubiquitination
1.53	1.27e-05	GO:0019941	modification-dependent protein catabolic process
1.14	1.47e-05	GO:0031323	regulation of cellular metabolic process
1.79	1.55e-05	GO:0031396	regulation of protein ubiquitination
1.53	2.14e-05	GO:0006511	ubiquitin-dependent protein catabolic process
1.27	2.46e-05	GO:0031325	positive regulation of cellular metabolic process
1.51	2.57e-05	GO:0051603	proteolysis involved in cellular protein catabolic process
1.32	2.59e-05	GO:0043933	macromolecular complex subunit organization
1.19	3.00e-05	GO:0048523	negative regulation of cellular process
1.33	3.12e-05	GO:0046907	intracellular transport
1.49	3.44e-05	GO:0030163	protein catabolic process
2.13	4.17e-05	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.04	4.39e-05	GO:0051443	positive regulation of ubiquitin-protein ligase activity
1.29	4.50e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.26	5.10e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.14	5.11e-05	GO:0080090	regulation of primary metabolic process
1.87	5.21e-05	GO:0031398	positive regulation of protein ubiquitination
1.61	5.57e-05	GO:0071156	regulation of cell cycle arrest
1.25	5.70e-05	GO:0009893	positive regulation of metabolic process
1.50	5.98e-05	GO:0044257	cellular protein catabolic process
1.95	6.73e-05	GO:0051438	regulation of ubiquitin-protein ligase activity
2.09	7.18e-05	GO:0051352	negative regulation of ligase activity
2.09	7.18e-05	GO:0051444	negative regulation of ubiquitin-protein ligase activity
1.61	1.14e-04	GO:0000075	cell cycle checkpoint
1.98	1.21e-04	GO:0051351	positive regulation of ligase activity
1.57	1.40e-04	GO:0032269	negative regulation of cellular protein metabolic process
1.08	1.49e-04	GO:0050794	regulation of cellular process
1.14	1.56e-04	GO:0060255	regulation of macromolecule metabolic process
1.91	1.62e-04	GO:0051340	regulation of ligase activity
1.27	1.70e-04	GO:0032268	regulation of cellular protein metabolic process
1.07	1.93e-04	GO:0065007	biological regulation
1.69	2.07e-04	GO:0031400	negative regulation of protein modification process
1.47	2.15e-04	GO:0010564	regulation of cell cycle process
1.17	2.42e-04	GO:0048519	negative regulation of biological process
1.44	2.54e-04	GO:0006886	intracellular protein transport
1.50	2.88e-04	GO:0051329	interphase of mitotic cell cycle
1.27	2.99e-04	GO:0032774	RNA biosynthetic process
1.98	3.26e-04	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.72	3.49e-04	GO:0000082	G1/S transition of mitotic cell cycle
1.12	3.65e-04	GO:0019222	regulation of metabolic process
1.08	4.51e-04	GO:0050789	regulation of biological process
1.35	4.51e-04	GO:0006259	DNA metabolic process
1.95	4.85e-04	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.24	4.89e-04	GO:0044085	cellular component biogenesis
2.01	4.99e-04	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.49	5.10e-04	GO:0051325	interphase
1.53	5.29e-04	GO:0051248	negative regulation of protein metabolic process
1.37	5.49e-04	GO:0034613	cellular protein localization
1.37	5.67e-04	GO:0070727	cellular macromolecule localization
1.25	6.64e-04	GO:0051246	regulation of protein metabolic process
1.51	8.25e-04	GO:0007346	regulation of mitotic cell cycle
1.48	1.08e-03	GO:0000087	M phase of mitotic cell cycle
1.33	1.08e-03	GO:0051726	regulation of cell cycle
1.18	1.40e-03	GO:0043412	macromolecule modification
1.84	1.81e-03	GO:0022904	respiratory electron transport chain
1.64	2.01e-03	GO:0010498	proteasomal protein catabolic process
1.64	2.01e-03	GO:0022415	viral reproductive process
1.64	2.01e-03	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.14	2.26e-03	GO:0048518	positive regulation of biological process
1.22	2.39e-03	GO:0051641	cellular localization
1.71	2.57e-03	GO:0045333	cellular respiration
1.30	2.81e-03	GO:0065003	macromolecular complex assembly
1.15	3.34e-03	GO:0048522	positive regulation of cellular process
1.46	3.98e-03	GO:0000280	nuclear division
1.46	3.98e-03	GO:0007067	mitosis
1.54	4.63e-03	GO:0033365	protein localization to organelle
1.45	4.78e-03	GO:0048285	organelle fission
1.31	6.45e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.66	9.02e-03	GO:0022900	electron transport chain
1.29	9.63e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.17	9.82e-03	GO:0006464	protein modification process
1.38	1.11e-02	GO:0006091	generation of precursor metabolites and energy
1.39	1.37e-02	GO:0034622	cellular macromolecular complex assembly
1.22	1.50e-02	GO:0051649	establishment of localization in cell
1.55	1.52e-02	GO:0016569	covalent chromatin modification
1.40	1.54e-02	GO:0006281	DNA repair
1.53	1.58e-02	GO:0022613	ribonucleoprotein complex biogenesis
1.36	1.71e-02	GO:0051247	positive regulation of protein metabolic process
1.69	1.91e-02	GO:0051320	S phase
2.11	2.12e-02	GO:0042773	ATP synthesis coupled electron transport
2.11	2.12e-02	GO:0042775	mitochondrial ATP synthesis coupled electron transport
1.69	2.29e-02	GO:0000084	S phase of mitotic cell cycle
1.50	2.64e-02	GO:0071843	cellular component biogenesis at cellular level
1.27	2.71e-02	GO:0031327	negative regulation of cellular biosynthetic process
1.24	2.72e-02	GO:0006351	transcription, DNA-dependent
1.36	2.85e-02	GO:0032270	positive regulation of cellular protein metabolic process
1.54	2.86e-02	GO:0016570	histone modification
1.63	3.05e-02	GO:0007093	mitotic cell cycle checkpoint
2.03	3.07e-02	GO:0006119	oxidative phosphorylation
2.21	3.13e-02	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
1.27	3.19e-02	GO:0009890	negative regulation of biosynthetic process
1.43	3.22e-02	GO:0034660	ncRNA metabolic process
1.39	3.48e-02	GO:0070647	protein modification by small protein conjugation or removal
1.60	3.82e-02	GO:0006333	chromatin assembly or disassembly
1.69	3.95e-02	GO:0034728	nucleosome organization
1.43	3.99e-02	GO:0015980	energy derivation by oxidation of organic compounds
1.21	4.10e-02	GO:0022607	cellular component assembly
1.42	4.19e-02	GO:0010608	posttranscriptional regulation of gene expression

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	1.23e-79	GO:0044424	intracellular part
1.16	6.12e-78	GO:0005622	intracellular
1.17	9.11e-55	GO:0043226	organelle
1.17	1.86e-54	GO:0043229	intracellular organelle
1.20	2.14e-53	GO:0005737	cytoplasm
1.18	1.86e-49	GO:0043227	membrane-bounded organelle
1.18	6.05e-49	GO:0043231	intracellular membrane-bounded organelle
1.37	3.63e-48	GO:0032991	macromolecular complex
1.26	1.45e-43	GO:0005634	nucleus
1.43	6.51e-37	GO:0044428	nuclear part
1.44	3.70e-36	GO:0005829	cytosol
1.41	9.31e-36	GO:0031974	membrane-enclosed lumen
1.41	1.72e-34	GO:0043233	organelle lumen
1.41	3.69e-34	GO:0070013	intracellular organelle lumen
1.23	1.06e-33	GO:0044446	intracellular organelle part
1.22	2.53e-33	GO:0044422	organelle part
1.45	3.08e-32	GO:0031981	nuclear lumen
1.20	3.01e-30	GO:0044444	cytoplasmic part
1.79	6.07e-26	GO:0030529	ribonucleoprotein complex
1.47	4.24e-25	GO:0005654	nucleoplasm
1.30	4.89e-25	GO:0043234	protein complex
1.30	2.29e-23	GO:0043228	non-membrane-bounded organelle
1.30	2.29e-23	GO:0043232	intracellular non-membrane-bounded organelle
1.36	1.79e-14	GO:0005739	mitochondrion
1.04	1.59e-11	GO:0044464	cell part
1.04	1.77e-11	GO:0005623	cell
1.86	2.08e-10	GO:0005840	ribosome
1.49	3.15e-10	GO:0005694	chromosome
1.42	3.62e-10	GO:0044451	nucleoplasm part
1.51	3.12e-09	GO:0044427	chromosomal part
1.86	3.09e-07	GO:0005681	spliceosomal complex
1.37	4.94e-07	GO:0044429	mitochondrial part
1.62	1.71e-06	GO:0000785	chromatin
1.41	3.69e-06	GO:0005730	nucleolus
1.33	4.12e-05	GO:0015630	microtubule cytoskeleton
1.31	1.04e-04	GO:0031967	organelle envelope
1.51	1.18e-04	GO:0005759	mitochondrial matrix
1.93	1.49e-04	GO:0071013	catalytic step 2 spliceosome
2.07	1.50e-04	GO:0005746	mitochondrial respiratory chain
2.01	2.09e-04	GO:0070469	respiratory chain
1.29	2.60e-04	GO:0031975	envelope
1.45	3.66e-04	GO:0005743	mitochondrial inner membrane
2.30	4.04e-04	GO:0005747	mitochondrial respiratory chain complex I
2.30	4.04e-04	GO:0030964	NADH dehydrogenase complex
2.30	4.04e-04	GO:0045271	respiratory chain complex I
1.71	4.78e-04	GO:0044455	mitochondrial membrane part
1.82	5.25e-04	GO:0016585	chromatin remodeling complex
1.42	5.90e-04	GO:0019866	organelle inner membrane
1.34	2.50e-03	GO:0005740	mitochondrial envelope
1.39	2.59e-03	GO:0005815	microtubule organizing center
1.34	2.97e-03	GO:0031966	mitochondrial membrane
1.38	3.23e-03	GO:0048471	perinuclear region of cytoplasm
1.47	7.03e-03	GO:0000228	nuclear chromosome
2.08	7.05e-03	GO:0000313	organellar ribosome
2.08	7.05e-03	GO:0005761	mitochondrial ribosome
1.17	9.70e-03	GO:0005856	cytoskeleton
1.57	1.02e-02	GO:0000775	chromosome, centromeric region
1.48	1.92e-02	GO:0005819	spindle
1.42	2.85e-02	GO:0005813	centrosome
2.58	3.08e-02	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.51	3.67e-02	GO:0044445	cytosolic part
1.88	4.06e-02	GO:0015935	small ribosomal subunit
1.18	4.84e-02	GO:0044430	cytoskeletal part
1.79	5.00e-02	GO:0000502	proteasome complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.22	4.55e-50	GO:0005515	protein binding
1.09	2.21e-28	GO:0005488	binding
1.55	5.21e-20	GO:0003723	RNA binding
1.28	3.05e-16	GO:0000166	nucleotide binding
1.17	2.34e-08	GO:0003676	nucleic acid binding
1.81	9.31e-07	GO:0003735	structural constituent of ribosome
1.21	1.58e-06	GO:0032553	ribonucleotide binding
1.21	1.58e-06	GO:0032555	purine ribonucleotide binding
1.21	1.73e-06	GO:0017076	purine nucleotide binding
1.21	1.84e-06	GO:0035639	purine ribonucleoside triphosphate binding
1.21	6.31e-05	GO:0030554	adenyl nucleotide binding
1.21	7.10e-05	GO:0032559	adenyl ribonucleotide binding
1.30	1.11e-04	GO:0019899	enzyme binding
2.42	1.29e-04	GO:0003954	NADH dehydrogenase activity
2.42	1.29e-04	GO:0008137	NADH dehydrogenase (ubiquinone) activity
2.42	1.29e-04	GO:0050136	NADH dehydrogenase (quinone) activity
2.32	1.30e-04	GO:0016655	oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
1.10	1.41e-04	GO:0003824	catalytic activity
1.20	1.70e-04	GO:0005524	ATP binding
1.24	2.77e-03	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.22	3.92e-03	GO:0030528	transcription regulator activity
1.26	6.96e-03	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.76	1.27e-02	GO:0008565	protein transporter activity
1.24	1.52e-02	GO:0016301	kinase activity