Motif ID: ZIC1..3.p2

Z-value: 1.059


Transcription factors associated with ZIC1..3.p2:

Gene SymbolEntrez IDGene Name
ZIC1 7545 Zic family member 1 (odd-paired homolog, Drosophila)
ZIC2 7546 Zic family member 2 (odd-paired homolog, Drosophila)
ZIC3 7547 Zic family member 3 (odd-paired homolog, Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZIC1chr3_+_147127151-0.686.5e-02Click!
ZIC2chr13_+_100633977,
chr13_+_100634257
-0.581.3e-01Click!
ZIC3chrX_+_1366483130.472.4e-01Click!


Activity profile for motif ZIC1..3.p2.

activity profile for motif ZIC1..3.p2


Sorted Z-values histogram for motif ZIC1..3.p2

Sorted Z-values for motif ZIC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_168727715 1.464 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr2_+_217498205 1.393 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr2_+_217498082 1.240 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr11_-_111782447 1.038 NM_001885
CRYAB
crystallin, alpha B
chr14_+_101292483 1.008


chr5_+_71403040 0.995 NM_005909
MAP1B
microtubule-associated protein 1B
chr7_-_150946031 0.994 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_-_150602020 0.910 ENSA
endosulfine alpha
chrX_-_15872921 0.807 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr17_-_5404304 0.779 NM_001162371
LOC728392
uncharacterized LOC728392
chr9_+_90112419 0.730 DAPK1
death-associated protein kinase 1
chrX_-_15872905 0.726


chr19_+_56159400 0.719 CCDC106
coiled-coil domain containing 106
chrX_-_51812249 0.699 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chr1_-_150602047 0.688 ENSA
endosulfine alpha
chr1_-_150602089 0.674 NM_004436
NM_207042
NM_207043
NM_207044
NM_207168
ENSA




endosulfine alpha




chr10_-_90712510 0.674 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr1_+_170633312 0.670 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr11_-_65640199 0.659 NM_016938
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr10_+_8097350 0.653 GATA3
GATA binding protein 3
chr6_+_72596699 0.651 RIMS1
regulating synaptic membrane exocytosis 1
chr16_+_55512801 0.650 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr2_+_200323088 0.650


chr1_+_155829259 0.645 NM_152280
SYT11
synaptotagmin XI
chr3_-_73673978 0.635 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr5_+_176237435 0.630 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chrX_-_15872882 0.626 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr14_+_101292451 0.606 MEG3
maternally expressed 3 (non-protein coding)
chr21_-_34100210 0.606 SYNJ1
synaptojanin 1
chr7_+_44144002 0.599 AEBP1
AE binding protein 1
chrX_-_15872938 0.587 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr2_+_8822112 0.576 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr1_-_150601911 0.571 ENSA
endosulfine alpha
chr16_+_86600856 0.558 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr17_-_19290471 0.554 NM_001198695
NM_002404
MFAP4

microfibrillar-associated protein 4

chr15_-_93616891 0.542 NM_001166288
NM_001166289
RGMA

RGM domain family, member A

chr16_+_86612114 0.541 NM_005250
FOXL1
forkhead box L1
chr19_+_16435734 0.540 KLF2
Kruppel-like factor 2 (lung)
chr19_+_16435632 0.532 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chrX_+_51927918 0.530 NM_001098800
NM_001242362
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B



melanoma antigen family D, 4
melanoma antigen family D, 4B



chr19_+_8478181 0.525 NM_001005415
NM_001005416
NM_016496
MARCH2


membrane-associated ring finger (C3HC4) 2


chr1_+_145438437 0.524 NM_006472
TXNIP
thioredoxin interacting protein
chr6_+_72596405 0.512 RIMS1
regulating synaptic membrane exocytosis 1
chr10_+_31610063 0.509 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr9_+_135037333 0.507 NM_032536
NTNG2
netrin G2
chr16_-_3074225 0.506 NM_001002017
NM_001002018
NM_017885
HCFC1R1


host cell factor C1 regulator 1 (XPO1 dependent)


chr1_-_85930610 0.505 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr7_+_44143945 0.505 NM_001129
AEBP1
AE binding protein 1
chr11_+_15133969 0.498 NM_001031853
INSC
inscuteable homolog (Drosophila)
chr7_-_150945731 0.492 NM_001003801
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr4_-_159092509 0.489 FAM198B
family with sequence similarity 198, member B
chr9_-_113800243 0.488 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr15_-_93617091 0.485 NM_001166283
RGMA
RGM domain family, member A
chr13_+_76210449 0.481 LMO7
LIM domain 7
chr3_+_45067750 0.479 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr17_-_28618836 0.477 BLMH
bleomycin hydrolase
chrX_-_15873094 0.477 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr5_-_9546157 0.476 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr11_+_19734821 0.471 NM_001244963
NM_145117
NM_182964
NAV2


neuron navigator 2


chr3_-_112358510 0.468 CCDC80
coiled-coil domain containing 80
chr5_-_168271852 0.453


chr4_+_123747939 0.448 FGF2
fibroblast growth factor 2 (basic)
chr14_-_30396811 0.448 NM_002742
PRKD1
protein kinase D1
chr12_+_56114150 0.444 NM_001199771
NM_002905
RDH5

retinol dehydrogenase 5 (11-cis/9-cis)

chr1_-_236228382 0.438 NID1
nidogen 1
chrX_+_101967103 0.437 NM_001004051
NM_001184874
NM_001184875
NM_001184876
NM_138437
GPRASP2




G protein-coupled receptor associated sorting protein 2




chr7_+_106809405 0.436 NM_001244262
NM_012257
HBP1

HMG-box transcription factor 1

chr3_-_129325175 0.430 NM_015103
PLXND1
plexin D1
chrX_-_15872871 0.429 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr6_-_139695349 0.424 NM_001168389
NM_001168388
CITED2

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

chr4_+_123747815 0.421 NM_002006
FGF2
fibroblast growth factor 2 (basic)
chr1_+_167905921 0.416 DCAF6
DDB1 and CUL4 associated factor 6
chr16_-_54318889 0.413 IRX3
iroquois homeobox 3
chr1_-_150602041 0.411 ENSA
endosulfine alpha
chr3_+_49449753 0.411 TCTA
T-cell leukemia translocation altered gene
chr1_-_236228374 0.407 NID1
nidogen 1
chr20_+_43029973 0.402 HNF4A
hepatocyte nuclear factor 4, alpha
chr11_-_70672644 0.399 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr8_-_91657739 0.398 TMEM64
transmembrane protein 64
chr3_+_110790460 0.397 NM_001243286
NM_015480
PVRL3

poliovirus receptor-related 3

chr17_+_39968961 0.394 NM_021939
FKBP10
FK506 binding protein 10, 65 kDa
chrX_+_134166318 0.393 NM_001078171
FAM127A
family with sequence similarity 127, member A
chr10_-_25012168 0.391 ARHGAP21
Rho GTPase activating protein 21
chr9_+_4490193 0.387 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr12_-_108733075 0.386 NM_001142343
NM_001142344
NM_004072
CMKLR1


chemokine-like receptor 1


chr12_+_56367696 0.383 NM_001252036
NM_001252037
NM_002868
RAB5B


RAB5B, member RAS oncogene family


chr17_-_37557851 0.379 NM_001184906
NM_032875
FBXL20

F-box and leucine-rich repeat protein 20

chr3_-_112358758 0.379 CCDC80
coiled-coil domain containing 80
chr11_-_118550354 0.378 NM_007180
TREH
trehalase (brush-border membrane glycoprotein)
chr2_+_28113598 0.375 BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr1_+_164528914 0.372 PBX1
pre-B-cell leukemia homeobox 1
chr22_-_19166276 0.369 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr5_+_137774632 0.369 NM_016606
REEP2
receptor accessory protein 2
chr11_+_19372270 0.367 NM_001111018
NAV2
neuron navigator 2
chr2_+_46769821 0.366 NM_012249
RHOQ
ras homolog gene family, member Q
chr11_+_113931228 0.366 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr21_-_34100228 0.365 NM_001160302
NM_001160306
SYNJ1

synaptojanin 1

chr1_-_150601554 0.363 NM_207045
NM_207046
NM_207047
ENSA


endosulfine alpha


chr1_+_89990396 0.361 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr11_-_64527369 0.361 PYGM
phosphorylase, glycogen, muscle
chr9_+_124061880 0.359 NM_000177
GSN
gelsolin
chr7_-_45960738 0.358 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr15_+_60296420 0.351 NM_012182
FOXB1
forkhead box B1
chr17_+_73043154 0.350 NM_015353
KCTD2
potassium channel tetramerisation domain containing 2
chr8_-_91657898 0.349 NM_001008495
NM_001146273
TMEM64

transmembrane protein 64

chr14_+_105941061 0.346 NM_001312
CRIP2
cysteine-rich protein 2
chrX_-_48931645 0.343 NM_007213
PRAF2
PRA1 domain family, member 2
chr2_+_28113612 0.340 BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr17_+_38230678 0.340 THRA
thyroid hormone receptor, alpha
chr15_+_60296506 0.339 FOXB1
forkhead box B1
chrX_+_51636608 0.338 NM_001005333
NM_006986
MAGED1

melanoma antigen family D, 1

chr5_-_121412805 0.336 NM_001178102
LOX
lysyl oxidase
chr19_-_50143350 0.336 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr2_+_149402321 0.335 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr9_+_124062105 0.334 GSN
gelsolin
chr20_-_57425957 0.332 GNAS-AS1
GNAS antisense RNA 1 (non-protein coding)
chr1_+_38273817 0.329 C1orf122
chromosome 1 open reading frame 122
chr19_+_12863406 0.329 NM_017682
BEST2
bestrophin 2
chr7_+_100199881 0.327 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr22_-_19166296 0.325 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr2_-_178257380 0.323 LOC100130691
uncharacterized LOC100130691
chr22_-_19166133 0.323 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr1_-_33168356 0.322 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr12_+_79258794 0.321 SYT1
synaptotagmin I
chrX_-_13956445 0.320


chr2_+_149402559 0.320 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chrX_+_54835492 0.320 NM_201222
MAGED2
melanoma antigen family D, 2
chr20_-_34025955 0.317 NM_000557
GDF5
growth differentiation factor 5
chr16_+_31483066 0.314 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr8_+_37654757 0.314 GPR124
G protein-coupled receptor 124
chr1_+_202431870 0.313 NM_032103
NM_032104
PPP1R12B

protein phosphatase 1, regulatory subunit 12B

chr17_-_15244898 0.311 NM_031898
TEKT3
tektin 3
chr20_+_57466509 0.307 GNAS
GNAS complex locus
chr14_-_103989112 0.307 CKB
creatine kinase, brain
chr3_+_133118789 0.304 NM_003571
BFSP2
beaded filament structural protein 2, phakinin
chr22_-_19165872 0.304 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr2_+_54952148 0.304 NM_001039753
EML6
echinoderm microtubule associated protein like 6
chrX_-_48858617 0.304 NM_020137
NM_207672
GRIPAP1

GRIP1 associated protein 1

chr15_-_93631751 0.303 NM_001166287
RGMA
RGM domain family, member A
chr10_-_79397394 0.302 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr2_+_28113655 0.301 BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chrX_+_9432980 0.301 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr2_-_175547471 0.298 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr15_-_48937795 0.297 NM_000138
FBN1
fibrillin 1
chr6_+_72596648 0.297 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr2_-_25016214 0.293 NM_001013663
PTRHD1
peptidyl-tRNA hydrolase domain containing 1
chr11_+_118478305 0.292 NM_001144758
NM_001144759
PHLDB1

pleckstrin homology-like domain, family B, member 1

chr17_+_19282058 0.290 MAPK7
mitogen-activated protein kinase 7
chr20_+_57466248 0.289 NM_000516
NM_001077488
NM_001077489
NM_080426
GNAS



GNAS complex locus



chrX_+_101967290 0.284 GPRASP2
G protein-coupled receptor associated sorting protein 2
chr7_-_105516923 0.284 NM_020725
NM_152749
ATXN7L1

ataxin 7-like 1

chr2_+_28113481 0.282 NM_199193
NM_199194
NM_004899
NM_199191
NM_199192
BRE




brain and reproductive organ-expressed (TNFRSF1A modulator)




chr11_+_66045645 0.281 NM_182553
CNIH2
cornichon homolog 2 (Drosophila)
chrX_+_149531439 0.281 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr11_-_67120943 0.280 NM_021173
POLD4
polymerase (DNA-directed), delta 4
chr21_-_34100316 0.279 NM_003895
NM_203446
SYNJ1

synaptojanin 1

chr20_+_56884749 0.278 NM_020673
RAB22A
RAB22A, member RAS oncogene family
chr19_-_17414083 0.278 NM_024527
ABHD8
abhydrolase domain containing 8
chr6_-_35464716 0.277 NM_003214
TEAD3
TEA domain family member 3
chr11_+_124609841 0.277 NRGN
neurogranin (protein kinase C substrate, RC3)
chr2_+_33172368 0.276 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr7_+_139025896 0.276 NM_197964
C7orf55
chromosome 7 open reading frame 55
chr5_+_179248089 0.275 SQSTM1
sequestosome 1
chr12_+_79258588 0.275 SYT1
synaptotagmin I
chr14_-_103988829 0.275 CKB
creatine kinase, brain
chr14_+_105190533 0.274 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr19_+_47105327 0.273 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr8_-_12990731 0.272 NM_006094
DLC1
deleted in liver cancer 1
chr2_-_241500459 0.272 ANKMY1
ankyrin repeat and MYND domain containing 1
chr8_+_37654833 0.272 GPR124
G protein-coupled receptor 124
chr1_+_167905796 0.271 NM_001017977
NM_001198956
NM_001198957
NM_018442
DCAF6



DDB1 and CUL4 associated factor 6



chr3_-_105587710 0.271 NM_170662
CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr17_-_73761216 0.270 NM_000154
GALK1
galactokinase 1
chr8_-_119634116 0.268 SAMD12
sterile alpha motif domain containing 12
chr16_+_23569045 0.266 UBFD1
ubiquitin family domain containing 1
chr4_+_129732427 0.266 PHF17
PHD finger protein 17
chr3_-_121379701 0.265 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr19_+_18208596 0.265 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr5_-_177659753 0.265 AGXT2L2
alanine-glyoxylate aminotransferase 2-like 2
chr1_+_167906055 0.265 DCAF6
DDB1 and CUL4 associated factor 6
chr15_-_93632161 0.264 NM_020211
RGMA
RGM domain family, member A
chr16_+_88493878 0.263 NM_001127464
ZNF469
zinc finger protein 469
chr22_-_28197469 0.260 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr1_+_246887591 0.260 SCCPDH
saccharopine dehydrogenase (putative)
chr17_-_8702438 0.260 NM_152599
MFSD6L
major facilitator superfamily domain containing 6-like
chr8_-_38325524 0.260 FGFR1
fibroblast growth factor receptor 1
chr9_-_73483933 0.259 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr14_+_29236882 0.259 FOXG1
forkhead box G1
chr11_+_124609775 0.258 NM_001126181
NM_006176
NRGN

neurogranin (protein kinase C substrate, RC3)

chr15_+_44084039 0.257 NM_001018108
NM_001199875
NM_001199876
SERF2


small EDRK-rich factor 2


chr12_+_117176085 0.257 NM_001109903
NM_032814
RNFT2

ring finger protein, transmembrane 2

chr12_+_79258517 0.257 SYT1
synaptotagmin I
chr14_+_101295409 0.255 MEG3
maternally expressed 3 (non-protein coding)
chr7_-_50860665 0.255 GRB10
growth factor receptor-bound protein 10
chr2_-_145275086 0.254 ZEB2
zinc finger E-box binding homeobox 2
chr9_-_115818967 0.252 NM_003408
ZFP37
zinc finger protein 37 homolog (mouse)
chrX_+_153409724 0.252 NM_020061
OPN1LW
opsin 1 (cone pigments), long-wave-sensitive
chr9_+_139877444 0.251 NM_207510
LCNL1
lipocalin-like 1
chr17_+_73043319 0.251 KCTD2
potassium channel tetramerisation domain containing 2
chr17_+_6918091 0.251 C17orf49
chromosome 17 open reading frame 49

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.17 1.60e-07 GO:0065007 biological regulation
1.30 6.42e-07 GO:0016043 cellular component organization
1.35 7.68e-07 GO:0071842 cellular component organization at cellular level
1.18 1.02e-06 GO:0050794 regulation of cellular process
1.10 2.12e-06 GO:0009987 cellular process
1.16 2.12e-06 GO:0050789 regulation of biological process
1.34 1.16e-05 GO:0048522 positive regulation of cellular process
1.31 1.99e-05 GO:0048518 positive regulation of biological process
1.26 3.03e-05 GO:0071840 cellular component organization or biogenesis
1.54 4.34e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.30 6.14e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.41 1.32e-04 GO:0009653 anatomical structure morphogenesis
1.32 3.69e-04 GO:0048523 negative regulation of cellular process
1.68 5.27e-04 GO:0051253 negative regulation of RNA metabolic process
1.39 8.41e-04 GO:0007399 nervous system development
1.30 8.85e-04 GO:0048519 negative regulation of biological process
1.52 9.78e-04 GO:0048699 generation of neurons
1.22 1.33e-03 GO:0032502 developmental process
1.24 1.43e-03 GO:0048856 anatomical structure development
1.61 1.57e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.41 1.82e-03 GO:0009893 positive regulation of metabolic process
1.35 2.10e-03 GO:0023051 regulation of signaling
1.42 2.10e-03 GO:0031325 positive regulation of cellular metabolic process
1.74 2.21e-03 GO:0007409 axonogenesis
1.72 2.47e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.65 2.59e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.60 2.79e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 2.89e-03 GO:0048731 system development
1.67 2.89e-03 GO:0000904 cell morphogenesis involved in differentiation
1.42 3.10e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.48 3.37e-03 GO:0031324 negative regulation of cellular metabolic process
1.26 3.69e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.75 3.70e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.48 3.86e-03 GO:0022008 neurogenesis
1.55 4.83e-03 GO:0030182 neuron differentiation
1.69 5.06e-03 GO:0048812 neuron projection morphogenesis
1.22 5.16e-03 GO:0007275 multicellular organismal development
1.77 5.80e-03 GO:0016568 chromatin modification
1.47 6.29e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.65 6.37e-03 GO:0031175 neuron projection development
1.14 7.17e-03 GO:0044237 cellular metabolic process
1.73 7.75e-03 GO:0007264 small GTPase mediated signal transduction
1.36 8.36e-03 GO:0009966 regulation of signal transduction
1.21 1.22e-02 GO:0031323 regulation of cellular metabolic process
1.56 1.41e-02 GO:0010629 negative regulation of gene expression
1.50 1.41e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 1.42e-02 GO:0051171 regulation of nitrogen compound metabolic process
3.44 1.45e-02 GO:0051149 positive regulation of muscle cell differentiation
1.18 1.47e-02 GO:0044260 cellular macromolecule metabolic process
1.52 1.52e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.57 1.58e-02 GO:0048666 neuron development
1.30 1.65e-02 GO:0048583 regulation of response to stimulus
1.42 1.76e-02 GO:0009892 negative regulation of metabolic process
1.54 1.83e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.27 2.28e-02 GO:0048869 cellular developmental process
1.51 2.38e-02 GO:0009890 negative regulation of biosynthetic process
1.20 2.41e-02 GO:0080090 regulation of primary metabolic process
1.60 2.42e-02 GO:0048858 cell projection morphogenesis
1.48 2.71e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.13 2.79e-02 GO:0044238 primary metabolic process
1.52 3.19e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.75 3.27e-02 GO:0060284 regulation of cell development
1.47 3.33e-02 GO:0016192 vesicle-mediated transport
1.59 3.42e-02 GO:0032990 cell part morphogenesis
1.27 3.57e-02 GO:0030154 cell differentiation
1.26 3.63e-02 GO:0006355 regulation of transcription, DNA-dependent
1.52 3.67e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.46 3.74e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.19 4.02e-02 GO:0023052 signaling
1.53 4.53e-02 GO:0000902 cell morphogenesis
1.25 4.65e-02 GO:0051252 regulation of RNA metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 9.03e-13 GO:0005622 intracellular
1.12 2.04e-11 GO:0044424 intracellular part
1.15 1.58e-07 GO:0005737 cytoplasm
1.12 3.25e-07 GO:0043229 intracellular organelle
1.12 4.19e-07 GO:0043226 organelle
1.19 6.33e-06 GO:0005634 nucleus
1.12 8.23e-06 GO:0043231 intracellular membrane-bounded organelle
1.12 8.34e-06 GO:0043227 membrane-bounded organelle
1.38 6.53e-04 GO:0005654 nucleoplasm
1.50 8.39e-04 GO:0031410 cytoplasmic vesicle
1.51 1.31e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.23 1.34e-03 GO:0043234 protein complex
1.47 2.77e-03 GO:0031982 vesicle
1.48 3.34e-03 GO:0031988 membrane-bounded vesicle
1.46 1.03e-02 GO:0044451 nucleoplasm part
1.18 1.23e-02 GO:0032991 macromolecular complex
1.25 1.54e-02 GO:0005829 cytosol
1.12 2.27e-02 GO:0044444 cytoplasmic part
1.71 3.53e-02 GO:0012506 vesicle membrane
1.92 4.24e-02 GO:0030136 clathrin-coated vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.23 4.82e-15 GO:0005515 protein binding
1.11 7.71e-11 GO:0005488 binding
1.75 8.88e-04 GO:0003712 transcription cofactor activity
1.74 9.89e-04 GO:0000988 protein binding transcription factor activity
1.74 9.89e-04 GO:0000989 transcription factor binding transcription factor activity
1.43 1.57e-03 GO:0001071 nucleic acid binding transcription factor activity
1.43 1.57e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.80 3.18e-03 GO:0008134 transcription factor binding
1.39 9.82e-03 GO:0030528 transcription regulator activity
1.67 3.35e-02 GO:0016563 transcription activator activity
2.02 3.74e-02 GO:0003714 transcription corepressor activity