Motif ID: bHLH_family.p2

Z-value: 3.124


Transcription factors associated with bHLH_family.p2:

Gene SymbolEntrez IDGene Name
ARNTL 406 aryl hydrocarbon receptor nuclear translocator-like
ARNTL2 56938 aryl hydrocarbon receptor nuclear translocator-like 2
CLOCK 9575 clock homolog (mouse)
HES6 55502 hairy and enhancer of split 6 (Drosophila)
HEY1 23462 hairy/enhancer-of-split related with YRPW motif 1
HEY2 23493 hairy/enhancer-of-split related with YRPW motif 2
HEYL 26508 hairy/enhancer-of-split related with YRPW motif-like
ID1 3397 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
MITF 4286 microphthalmia-associated transcription factor
MLXIPL 51085 MLX interacting protein-like
MNT 4335 MAX binding protein
MXD3 83463 MAX dimerization protein 3
MXD4 10608 MAX dimerization protein 4
MXI1 4601 MAX interactor 1
NPAS2 4862 neuronal PAS domain protein 2
OLIG1 116448 oligodendrocyte transcription factor 1
OLIG2 10215 oligodendrocyte lineage transcription factor 2
TFE3 7030 transcription factor binding to IGHM enhancer 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NPAS2chr2_+_101436491-0.945.3e-04Click!
MITFchr3_+_69788562-0.921.2e-03Click!
MXD4chr4_-_2263706-0.893.2e-03Click!
CLOCKchr4_-_564129680.866.2e-03Click!
HEY2chr6_+_1260707380.849.4e-03Click!
MXD3chr5_-_176738831-0.821.3e-02Click!
ARNTL2chr12_+_274857670.811.4e-02Click!
HES6chr2_-_239148545-0.705.4e-02Click!
HEY1chr8_-_806798970.705.5e-02Click!
HEYLchr1_-_400986390.648.9e-02Click!
TFE3chrX_-_48900932-0.581.3e-01Click!
OLIG2chr21_+_343982100.541.6e-01Click!
OLIG1chr21_+_34442446,
chr21_+_34444004,
chr21_+_34442550
0.531.8e-01Click!
ARNTLchr11_+_13299260-0.403.2e-01Click!
ID1chr20_+_30193083-0.363.8e-01Click!
MNTchr17_-_23042170.068.8e-01Click!
MLXIPLchr7_-_730388140.059.1e-01Click!
MXI1chr10_+_111969988,
chr10_+_111985628
0.009.9e-01Click!


Activity profile for motif bHLH_family.p2.

activity profile for motif bHLH_family.p2


Sorted Z-values histogram for motif bHLH_family.p2

Sorted Z-values for motif bHLH_family.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of bHLH_family.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_95653272 10.557 ESRP1
epithelial splicing regulatory protein 1
chr16_+_68679198 9.510 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr8_+_95653340 8.755 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr8_+_95653399 8.345 ESRP1
epithelial splicing regulatory protein 1
chr8_+_120220554 7.591 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr16_-_68269948 5.754 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr22_+_40390935 5.550 NM_138435
FAM83F
family with sequence similarity 83, member F
chr16_+_68679229 5.466 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr8_-_75233461 4.703 NM_020647
JPH1
junctophilin 1
chr19_-_19738973 4.623 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr1_+_183155393 4.454 LAMC2
laminin, gamma 2
chr19_+_35739282 4.214 LSR
lipolysis stimulated lipoprotein receptor
chr1_+_1981902 4.166 NM_002744
PRKCZ
protein kinase C, zeta
chr1_+_183155361 4.111 LAMC2
laminin, gamma 2
chr19_+_10765106 3.979 ILF3
interleukin enhancer binding factor 3, 90kDa
chr17_+_9548853 3.820 NM_153210
USP43
ubiquitin specific peptidase 43
chr7_+_16793320 3.807 NM_014399
TSPAN13
tetraspanin 13
chr14_-_61747956 3.598 TMEM30B
transmembrane protein 30B
chr6_-_136871956 3.413 NM_001198616
NM_001198617
NM_003980
MAP7


microtubule-associated protein 7


chr17_-_76124791 3.408 NM_001127198
TMC6
transmembrane channel-like 6
chr13_-_20767036 3.370 GJB2
gap junction protein, beta 2, 26kDa
chr6_-_136871542 3.321 MAP7
microtubule-associated protein 7
chr19_+_10764896 3.274 NM_001137673
NM_004516
NM_012218
NM_017620
NM_153464
ILF3




interleukin enhancer binding factor 3, 90kDa




chr1_+_183155173 3.240 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr19_+_38755422 3.075 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr1_+_233463513 3.036 NM_032435
KIAA1804
mixed lineage kinase 4
chr1_+_150255228 3.030 NM_144697
C1orf51
chromosome 1 open reading frame 51
chr3_-_57113292 2.925 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr11_+_72929392 2.911 NM_176071
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr6_+_37137882 2.877 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr17_+_55163077 2.835 NM_001242903
NM_001242902
AKAP1

A kinase (PRKA) anchor protein 1

chr19_+_10764987 2.757 ILF3
interleukin enhancer binding factor 3, 90kDa
chr19_+_7702020 2.750 STXBP2
syntaxin binding protein 2
chr2_-_215896809 2.743 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr3_-_49941300 2.715 NM_001244937
NM_002447
MST1R

macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

chr12_-_28122884 2.677 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr6_+_138188352 2.625 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr19_+_18284578 2.623 NM_006332
IFI30
interferon, gamma-inducible protein 30
chr20_+_61273823 2.599 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr2_+_27665232 2.560 NM_001168364
NM_173853
KRTCAP3

keratinocyte associated protein 3

chr19_+_7702010 2.539 STXBP2
syntaxin binding protein 2
chr19_+_38755238 2.519 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr17_-_17109601 2.500 PLD6
phospholipase D family, member 6
chr19_+_35739519 2.498 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr2_+_173292344 2.442 ITGA6
integrin, alpha 6
chr17_-_17109630 2.437 NM_178836
PLD6
phospholipase D family, member 6
chr17_+_78075390 2.437 GAA
glucosidase, alpha; acid
chr19_+_38755097 2.423 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr11_+_45944155 2.420 GYLTL1B
glycosyltransferase-like 1B
chr16_+_68771192 2.420 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr15_+_89182038 2.413 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr19_+_7701976 2.408 NM_001127396
NM_006949
STXBP2

syntaxin binding protein 2

chr11_+_72929302 2.408 NM_002564
NM_176072
P2RY2

purinergic receptor P2Y, G-protein coupled, 2

chr17_-_4458618 2.405 NM_001105538
NM_014520
MYBBP1A

MYB binding protein (P160) 1a

chr14_-_94849552 2.365 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_-_159915382 2.361 NM_001135050
NM_020789
IGSF9

immunoglobulin superfamily, member 9

chrX_+_16804531 2.290 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr1_+_65613211 2.287 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr2_+_223289212 2.280 SGPP2
sphingosine-1-phosphate phosphatase 2
chr6_+_150464156 2.276 NM_030949
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr18_+_23806385 2.272 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr5_+_140220811 2.254 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr16_+_68771214 2.251 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr11_+_68079999 2.227 NM_002335
LRP5
low density lipoprotein receptor-related protein 5
chr17_-_76124767 2.199 TMC6
transmembrane channel-like 6
chr18_+_33877630 2.194 NM_025135
FHOD3
formin homology 2 domain containing 3
chr17_-_2614926 2.186 NM_015229
KIAA0664
KIAA0664
chr1_-_201368716 2.172 LAD1
ladinin 1
chr1_-_160990862 2.154 F11R
F11 receptor
chr17_-_39274587 2.148 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr3_-_124931562 2.145 NM_024628
SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr15_+_90728118 2.139 NM_020210
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr1_-_201368617 2.117 NM_005558
LAD1
ladinin 1
chr1_-_113498615 2.116 NM_001166496
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr17_-_7197896 2.113 YBX2
Y box binding protein 2
chr5_+_68788387 2.104 NM_001205254
OCLN
occludin
chr22_-_37882214 2.082 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr14_+_65171243 2.070 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr8_+_98788014 2.065 LAPTM4B
lysosomal protein transmembrane 4 beta
chr10_-_76995685 2.059 NM_144589
COMTD1
catechol-O-methyltransferase domain containing 1
chr1_-_201368434 2.046 LAD1
ladinin 1
chr18_-_74844762 2.045 NM_001025100
NM_001025101
MBP

myelin basic protein

chr9_-_126030792 2.027 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chrX_-_102565805 2.018 NM_001168399
NM_001168400
NM_001168401
NM_032621
BEX2



brain expressed X-linked 2



chr9_+_115913266 1.999 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr12_-_58146110 1.997 CDK4
cyclin-dependent kinase 4
chr3_+_113666544 1.987 NM_173570
ZDHHC23
zinc finger, DHHC-type containing 23
chr12_-_58146025 1.970 CDK4
cyclin-dependent kinase 4
chr12_-_58146108 1.963 CDK4
cyclin-dependent kinase 4
chr17_-_7197866 1.952 NM_015982
YBX2
Y box binding protein 2
chr12_-_85306539 1.940 SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr1_+_35247838 1.938 NM_001005752
GJB3
gap junction protein, beta 3, 31kDa
chr2_+_223289285 1.933 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr12_-_85306579 1.912 NM_001146335
NM_018057
NM_182767
SLC6A15


solute carrier family 6 (neutral amino acid transporter), member 15


chr1_-_12677347 1.898 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr19_+_35739778 1.843 LSR
lipolysis stimulated lipoprotein receptor
chr1_+_203097427 1.834 ADORA1
adenosine A1 receptor
chr16_+_66914380 1.834 NM_020786
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr9_-_126030854 1.807 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr12_-_58146118 1.804 NM_000075
CDK4
cyclin-dependent kinase 4
chr1_-_160990971 1.783 NM_016946
F11R
F11 receptor
chr17_-_7197811 1.781 YBX2
Y box binding protein 2
chr19_+_18284619 1.778 IFI30
interferon, gamma-inducible protein 30
chr16_+_67233013 1.763 NM_024712
ELMO3
engulfment and cell motility 3
chr5_+_167718485 1.763 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr14_-_55369163 1.747 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr5_+_150827204 1.723 SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr2_+_47596286 1.712 NM_002354
EPCAM
epithelial cell adhesion molecule
chr1_+_28261503 1.706 NM_001009568
NM_014474
SMPDL3B

sphingomyelin phosphodiesterase, acid-like 3B

chr17_-_74497406 1.700 NM_024599
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr7_-_22396511 1.687 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr4_-_84255895 1.673 NM_001199830
HPSE
heparanase
chr1_+_11796211 1.666 AGTRAP
angiotensin II receptor-associated protein
chr19_+_18284631 1.650 IFI30
interferon, gamma-inducible protein 30
chr17_-_41623652 1.649 NM_001079675
ETV4
ets variant 4
chr4_-_84256304 1.640 NM_001166498
NM_006665
HPSE

heparanase

chr11_+_120081669 1.635 NM_178507
OAF
OAF homolog (Drosophila)
chr6_+_7541863 1.629 NM_001008844
NM_004415
DSP

desmoplakin

chr7_+_26191732 1.628 NM_004289
NFE2L3
nuclear factor (erythroid-derived 2)-like 3
chr19_+_1067293 1.628 HMHA1
histocompatibility (minor) HA-1
chr2_-_31352489 1.611 NM_001253827
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr4_-_84255999 1.597 HPSE
heparanase
chr2_-_110873353 1.595 MALL
mal, T-cell differentiation protein-like
chr16_+_68771304 1.588 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr2_+_17721806 1.575 NM_003385
VSNL1
visinin-like 1
chr17_-_7165788 1.571 CLDN7
claudin 7
chr3_+_183967469 1.565 ECE2
endothelin converting enzyme 2
chr4_-_84256012 1.552 NM_001098540
HPSE
heparanase
chr9_-_140196702 1.546 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr2_+_17721983 1.545 VSNL1
visinin-like 1
chr2_-_208634051 1.540 NM_003468
FZD5
frizzled family receptor 5
chr11_+_1860232 1.534 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr6_-_80656870 1.521 NM_022726
ELOVL4
ELOVL fatty acid elongase 4
chr12_-_85306569 1.521 SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr16_+_2570322 1.518 NM_001145815
NM_015944
AMDHD2

amidohydrolase domain containing 2

chr8_-_15095791 1.507 NM_139167
SGCZ
sarcoglycan, zeta
chr1_-_113498828 1.506 NM_003051
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr3_+_183967414 1.502 NM_014693
NM_032331
ECE2

endothelin converting enzyme 2

chr1_+_11796128 1.501 NM_001040194
NM_001040195
NM_001040196
NM_001040197
NM_020350
AGTRAP




angiotensin II receptor-associated protein




chr2_-_110874142 1.494 NM_005434
MALL
mal, T-cell differentiation protein-like
chr11_-_61684981 1.491 NM_013401
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr6_-_143832770 1.485 NM_032020
FUCA2
fucosidase, alpha-L- 2, plasma
chr1_+_11796177 1.483 AGTRAP
angiotensin II receptor-associated protein
chr2_-_31361284 1.480 GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr14_+_67999915 1.477 NM_020715
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr19_-_291335 1.469 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr1_+_26872306 1.459 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr2_-_31361591 1.451 NM_001253826
NM_024572
GALNT14

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)

chr6_+_7541837 1.426 DSP
desmoplakin
chr5_-_150603615 1.421 CCDC69
coiled-coil domain containing 69
chr14_-_24036532 1.417 AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr12_+_101673895 1.414 NM_014503
UTP20
UTP20, small subunit (SSU) processome component, homolog (yeast)
chr8_-_66701175 1.412 NM_002603
PDE7A
phosphodiesterase 7A
chr18_-_47721165 1.406 NM_001080467
MYO5B
myosin VB
chr5_-_1882764 1.400 NM_016358
IRX4
iroquois homeobox 4
chr1_-_204329043 1.400 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr17_-_38657814 1.393 NM_032865
TNS4
tensin 4
chr2_-_110873638 1.386 MALL
mal, T-cell differentiation protein-like
chrX_-_100662905 1.375 NM_000169
GLA
galactosidase, alpha
chr8_-_144654921 1.374 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr11_-_11643542 1.373 NM_198516
GALNTL4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
chr19_-_291168 1.373 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr16_+_71660063 1.369 NM_001017967
NM_052858
MARVELD3

MARVEL domain containing 3

chr11_+_7535213 1.365 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr13_-_20767100 1.361 NM_004004
GJB2
gap junction protein, beta 2, 26kDa
chr1_-_21059132 1.360 NM_001103160
NM_001103161
SH2D5

SH2 domain containing 5

chr1_+_44440623 1.354 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr5_+_149737296 1.351 TCOF1
Treacher Collins-Franceschetti syndrome 1
chr17_-_39280377 1.348 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr4_+_75310852 1.336 NM_001657
AREG
amphiregulin
chr1_+_44440595 1.327 NM_001039457
NM_004047
ATP6V0B

ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b

chrX_-_100662788 1.323 GLA
galactosidase, alpha
chr3_+_184032319 1.310 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr12_-_121341921 1.310 SPPL3
signal peptide peptidase-like 3
chr5_+_149737201 1.310 NM_000356
NM_001008657
NM_001135243
NM_001135244
NM_001135245
NM_001195141
TCOF1





Treacher Collins-Franceschetti syndrome 1





chr4_-_103266396 1.305 NM_001135147
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr12_-_123380628 1.301 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr16_-_1525006 1.300 CLCN7
chloride channel 7
chr1_+_151483861 1.299 NM_020770
CGN
cingulin
chr5_+_34656367 1.298 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr17_-_7166263 1.296 NM_001185023
NM_001307
CLDN7

claudin 7

chr7_+_26403944 1.286 NM_001199838
SNX10
sorting nexin 10
chr5_-_150603649 1.280 NM_015621
CCDC69
coiled-coil domain containing 69
chr19_+_1067536 1.278 HMHA1
histocompatibility (minor) HA-1
chr5_+_34656482 1.275 RAI14
retinoic acid induced 14
chrX_+_105937067 1.274 NM_024539
RNF128
ring finger protein 128
chr9_-_33473846 1.263 NOL6
nucleolar protein family 6 (RNA-associated)
chr11_+_20409075 1.261 NM_001145166
NM_001145167
NM_005788
PRMT3


protein arginine methyltransferase 3


chr4_-_36245893 1.258 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_+_34656595 1.255 NM_001145520
RAI14
retinoic acid induced 14
chr4_-_10023094 1.254 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr3_+_47021146 1.249 NM_015175
NBEAL2
neurobeachin-like 2
chr6_-_13486382 1.249 NM_001242628
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr6_+_7541892 1.246 DSP
desmoplakin
chr9_-_135545327 1.240 DDX31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr1_+_234349995 1.238 SLC35F3
solute carrier family 35, member F3
chr1_+_26872342 1.227 NM_001006665
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr9_+_35673852 1.225 NM_001216
CA9
carbonic anhydrase IX
chr8_+_32405727 1.223 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr9_+_706744 1.219 NM_153186
KANK1
KN motif and ankyrin repeat domains 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.11 3.65e-14 GO:0009987 cellular process
1.14 4.45e-05 GO:0044237 cellular metabolic process
1.18 7.40e-05 GO:0044260 cellular macromolecule metabolic process
2.23 1.75e-04 GO:0042254 ribosome biogenesis
1.13 2.09e-04 GO:0044238 primary metabolic process
1.29 3.25e-04 GO:0010467 gene expression
1.77 1.01e-03 GO:0034660 ncRNA metabolic process
1.15 1.31e-03 GO:0043170 macromolecule metabolic process
1.11 2.61e-03 GO:0008152 metabolic process
1.86 3.38e-03 GO:0022613 ribonucleoprotein complex biogenesis
1.83 4.35e-03 GO:0071843 cellular component biogenesis at cellular level
1.17 2.16e-02 GO:0006807 nitrogen compound metabolic process
1.17 3.32e-02 GO:0034641 cellular nitrogen compound metabolic process
1.24 3.42e-02 GO:0016070 RNA metabolic process
1.78 3.44e-02 GO:0034470 ncRNA processing

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.77 7.02e-10 GO:0005730 nucleolus
1.12 2.86e-08 GO:0005737 cytoplasm
1.30 4.47e-08 GO:0031974 membrane-enclosed lumen
1.29 1.66e-07 GO:0043233 organelle lumen
1.29 2.56e-07 GO:0070013 intracellular organelle lumen
1.08 5.44e-07 GO:0005622 intracellular
1.08 6.14e-07 GO:0044424 intracellular part
1.32 8.17e-07 GO:0031981 nuclear lumen
1.28 2.54e-06 GO:0044428 nuclear part
1.14 4.45e-06 GO:0044444 cytoplasmic part
1.15 8.54e-06 GO:0044446 intracellular organelle part
1.14 2.29e-05 GO:0044422 organelle part
3.84 8.98e-05 GO:0044452 nucleolar part
1.08 2.95e-04 GO:0043226 organelle
1.08 3.18e-04 GO:0043229 intracellular organelle
1.08 9.35e-04 GO:0043231 intracellular membrane-bounded organelle
1.08 1.03e-03 GO:0043227 membrane-bounded organelle
1.18 6.55e-03 GO:0043228 non-membrane-bounded organelle
1.18 6.55e-03 GO:0043232 intracellular non-membrane-bounded organelle
2.09 1.44e-02 GO:0042470 melanosome
2.09 1.44e-02 GO:0048770 pigment granule
1.33 1.65e-02 GO:0005626 insoluble fraction
1.25 2.66e-02 GO:0005654 nucleoplasm
1.27 4.27e-02 GO:0000267 cell fraction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 2.13e-10 GO:0005515 protein binding
1.06 5.37e-05 GO:0005488 binding
1.22 9.71e-04 GO:0000166 nucleotide binding
1.26 1.99e-03 GO:0016740 transferase activity
1.27 2.88e-03 GO:0032559 adenyl ribonucleotide binding
2.42 3.91e-03 GO:0015171 amino acid transmembrane transporter activity
1.26 4.68e-03 GO:0030554 adenyl nucleotide binding
1.26 5.39e-03 GO:0005524 ATP binding
1.22 8.80e-03 GO:0032553 ribonucleotide binding
1.22 8.80e-03 GO:0032555 purine ribonucleotide binding
2.22 8.86e-03 GO:0005275 amine transmembrane transporter activity
1.35 1.30e-02 GO:0003723 RNA binding
1.22 1.48e-02 GO:0017076 purine nucleotide binding
1.22 1.91e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.11 1.93e-02 GO:0003824 catalytic activity
1.46 3.43e-02 GO:0004674 protein serine/threonine kinase activity