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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for IRF6_IRF4_IRF5

Z-value: 0.64

Motif logo

Transcription factors associated with IRF6_IRF4_IRF5

Gene Symbol Gene ID Gene Info
ENSG00000117595.6 IRF6
ENSG00000137265.10 IRF4
ENSG00000128604.14 IRF5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF6hg19_v2_chr1_-_209979465_2099794940.979.1e-05Click!
IRF5hg19_v2_chr7_+_128577972_1285780470.938.5e-04Click!
IRF4hg19_v2_chr6_+_391739_391759-0.294.8e-01Click!

Activity profile of IRF6_IRF4_IRF5 motif

Sorted Z-values of IRF6_IRF4_IRF5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF6_IRF4_IRF5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_118134997 2.35 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr11_-_118135160 1.89 ENST00000438295.2
MPZL2
myelin protein zero-like 2
chr8_+_8559406 0.85 ENST00000519106.1
CLDN23
claudin 23
chr12_+_113344755 0.80 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr10_-_10836919 0.74 ENST00000602763.1
ENST00000415590.2
ENST00000434919.2
SFTA1P
surfactant associated 1, pseudogene
chr15_+_41136586 0.73 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr11_+_32851487 0.70 ENST00000257836.3
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr12_+_113344811 0.68 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr17_-_39677971 0.66 ENST00000393976.2
KRT15
keratin 15
chr12_+_113376157 0.62 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr10_-_10836865 0.59 ENST00000446372.2
SFTA1P
surfactant associated 1, pseudogene
chr12_+_113344582 0.59 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_+_86889769 0.50 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr2_-_70780572 0.48 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr9_-_32526184 0.46 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr11_+_130029457 0.46 ENST00000278742.5
ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr5_+_68788594 0.44 ENST00000396442.2
ENST00000380766.2
OCLN
occludin
chr17_-_7164410 0.43 ENST00000574070.1
CLDN7
claudin 7
chr10_+_134210672 0.40 ENST00000305233.5
ENST00000368609.4
PWWP2B
PWWP domain containing 2B
chr1_-_59043166 0.39 ENST00000371225.2
TACSTD2
tumor-associated calcium signal transducer 2
chr9_-_32526299 0.38 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr21_+_42733870 0.38 ENST00000330714.3
ENST00000436410.1
ENST00000435611.1
MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr7_-_20256965 0.37 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr2_+_163175394 0.36 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr4_-_89080003 0.36 ENST00000237612.3
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr1_-_160990886 0.36 ENST00000537746.1
F11R
F11 receptor
chr1_-_159915386 0.36 ENST00000361509.3
ENST00000368094.1
IGSF9
immunoglobulin superfamily, member 9
chr15_-_45670924 0.34 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr2_+_120770686 0.33 ENST00000331393.4
ENST00000443124.1
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr21_+_42792442 0.33 ENST00000398600.2
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr2_+_68961934 0.31 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr2_+_68961905 0.31 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr4_+_89378261 0.30 ENST00000264350.3
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr4_+_144257915 0.29 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr4_-_100575781 0.28 ENST00000511828.1
RP11-766F14.2
Protein LOC285556
chr16_+_30751953 0.27 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr11_-_104817919 0.26 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr6_+_43738444 0.25 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA
vascular endothelial growth factor A
chr11_+_128563652 0.25 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr7_+_30323923 0.23 ENST00000323037.4
ZNRF2
zinc and ring finger 2
chr11_+_65554493 0.23 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr6_+_106546808 0.22 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr10_+_71561649 0.22 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chr3_-_182880541 0.22 ENST00000470251.1
ENST00000265598.3
LAMP3
lysosomal-associated membrane protein 3
chr12_+_46123448 0.22 ENST00000334344.6
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr14_-_102552659 0.22 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr21_-_34914394 0.22 ENST00000361093.5
ENST00000381815.4
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr21_+_42798094 0.21 ENST00000398598.3
ENST00000455164.2
ENST00000424365.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr10_+_71561630 0.21 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr2_-_163175133 0.19 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr1_+_179262905 0.19 ENST00000539888.1
ENST00000540564.1
ENST00000535686.1
ENST00000367619.3
SOAT1
sterol O-acyltransferase 1
chr13_-_46961580 0.18 ENST00000378787.3
ENST00000378797.2
ENST00000429979.1
ENST00000378781.3
KIAA0226L
KIAA0226-like
chr13_-_76056250 0.17 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
TBC1D4
TBC1 domain family, member 4
chr2_+_68962014 0.17 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr5_-_35230434 0.17 ENST00000504500.1
PRLR
prolactin receptor
chr6_+_26087509 0.15 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE
hemochromatosis
chr2_+_113299990 0.15 ENST00000537335.1
ENST00000417433.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr20_+_20033158 0.15 ENST00000340348.6
ENST00000377309.2
ENST00000389656.3
ENST00000377306.1
ENST00000245957.5
ENST00000377303.2
ENST00000475466.1
C20orf26
chromosome 20 open reading frame 26
chr4_+_144258021 0.14 ENST00000262994.4
GAB1
GRB2-associated binding protein 1
chr2_-_220252603 0.14 ENST00000322176.7
ENST00000273075.4
DNPEP
aspartyl aminopeptidase
chrX_-_110655391 0.14 ENST00000356915.2
ENST00000356220.3
DCX
doublecortin
chrX_-_30877837 0.14 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr2_-_55920952 0.13 ENST00000447944.2
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr12_-_31477072 0.13 ENST00000454658.2
FAM60A
family with sequence similarity 60, member A
chr12_+_113376249 0.13 ENST00000551007.1
ENST00000548514.1
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr16_-_74734672 0.13 ENST00000306247.7
ENST00000575686.1
MLKL
mixed lineage kinase domain-like
chr1_-_153514241 0.13 ENST00000368718.1
ENST00000359215.1
S100A5
S100 calcium binding protein A5
chr2_-_231989808 0.13 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr2_+_7017796 0.13 ENST00000382040.3
RSAD2
radical S-adenosyl methionine domain containing 2
chr6_-_137365402 0.12 ENST00000541547.1
IL20RA
interleukin 20 receptor, alpha
chr15_-_26108355 0.12 ENST00000356865.6
ATP10A
ATPase, class V, type 10A
chr6_+_89855765 0.12 ENST00000275072.4
PM20D2
peptidase M20 domain containing 2
chr1_-_109940550 0.12 ENST00000256637.6
SORT1
sortilin 1
chr6_+_26087646 0.12 ENST00000309234.6
HFE
hemochromatosis
chr4_-_11431188 0.12 ENST00000510712.1
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr19_+_41222998 0.11 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr14_+_39736582 0.11 ENST00000556148.1
ENST00000348007.3
CTAGE5
CTAGE family, member 5
chr7_-_77045617 0.11 ENST00000257626.7
GSAP
gamma-secretase activating protein
chr5_-_176057518 0.11 ENST00000393693.2
SNCB
synuclein, beta
chr3_-_179169181 0.11 ENST00000497513.1
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr3_+_118892362 0.11 ENST00000497685.1
ENST00000264234.3
UPK1B
uroplakin 1B
chr8_-_22926526 0.11 ENST00000347739.3
ENST00000542226.1
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr12_-_50616382 0.10 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr10_+_71561704 0.10 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr2_-_75938115 0.10 ENST00000321027.3
GCFC2
GC-rich sequence DNA-binding factor 2
chr15_-_30114231 0.10 ENST00000356107.6
ENST00000545208.2
TJP1
tight junction protein 1
chr11_+_100862811 0.10 ENST00000303130.2
TMEM133
transmembrane protein 133
chr2_-_170219079 0.09 ENST00000263816.3
LRP2
low density lipoprotein receptor-related protein 2
chr20_-_25038804 0.09 ENST00000323482.4
ACSS1
acyl-CoA synthetase short-chain family member 1
chr11_+_63655987 0.09 ENST00000509502.2
ENST00000512060.1
MARK2
MAP/microtubule affinity-regulating kinase 2
chr8_-_22926623 0.09 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr5_-_35938674 0.09 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL
calcyphosine-like
chr3_+_127634069 0.09 ENST00000405109.1
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr19_+_7600584 0.09 ENST00000600737.1
PNPLA6
patatin-like phospholipase domain containing 6
chr6_-_27799305 0.09 ENST00000357549.2
HIST1H4K
histone cluster 1, H4k
chr15_+_74287009 0.09 ENST00000395135.3
PML
promyelocytic leukemia
chr9_-_139640458 0.09 ENST00000476567.1
LCN6
lipocalin 6
chr4_+_147096837 0.09 ENST00000296581.5
ENST00000502781.1
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr18_+_42260861 0.09 ENST00000282030.5
SETBP1
SET binding protein 1
chr2_-_111435610 0.09 ENST00000447014.1
ENST00000420328.1
ENST00000535254.1
ENST00000409311.1
ENST00000302759.6
BUB1
BUB1 mitotic checkpoint serine/threonine kinase
chr5_-_95297534 0.08 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chrX_-_54824673 0.08 ENST00000218436.6
ITIH6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr4_+_57371509 0.08 ENST00000360096.2
ARL9
ADP-ribosylation factor-like 9
chr15_+_90544532 0.08 ENST00000268154.4
ZNF710
zinc finger protein 710
chr4_-_88141755 0.08 ENST00000273963.5
KLHL8
kelch-like family member 8
chr16_+_12058961 0.08 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr15_+_28624878 0.08 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr9_-_33264676 0.08 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr7_+_141478242 0.08 ENST00000247881.2
TAS2R4
taste receptor, type 2, member 4
chr1_-_54355430 0.08 ENST00000371399.1
ENST00000072644.1
ENST00000412288.1
YIPF1
Yip1 domain family, member 1
chr9_+_95820966 0.08 ENST00000375472.3
ENST00000465709.1
SUSD3
sushi domain containing 3
chr10_+_15139394 0.08 ENST00000441850.1
RPP38
ribonuclease P/MRP 38kDa subunit
chr11_-_85522172 0.08 ENST00000316356.4
ENST00000389960.4
ENST00000527523.1
SYTL2
synaptotagmin-like 2
chr3_+_45429998 0.08 ENST00000265537.3
ENST00000415258.1
ENST00000431023.1
ENST00000414984.1
LARS2
leucyl-tRNA synthetase 2, mitochondrial
chr22_+_36044411 0.08 ENST00000409652.4
APOL6
apolipoprotein L, 6
chr12_-_71148413 0.08 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr6_-_167797887 0.07 ENST00000476779.2
ENST00000460930.2
ENST00000397829.4
ENST00000366827.2
TCP10
t-complex 10
chr9_-_103115185 0.07 ENST00000374902.4
TEX10
testis expressed 10
chr4_-_75719896 0.07 ENST00000395743.3
BTC
betacellulin
chr12_+_46123682 0.07 ENST00000422737.1
ARID2
AT rich interactive domain 2 (ARID, RFX-like)
chr7_+_37960163 0.07 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1
ependymin related 1
chr10_+_123923205 0.07 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr14_+_94577074 0.07 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr1_-_44497024 0.07 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr4_+_144303093 0.07 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr18_-_33647487 0.07 ENST00000590898.1
ENST00000357384.4
ENST00000319040.6
ENST00000588737.1
ENST00000399022.4
RPRD1A
regulation of nuclear pre-mRNA domain containing 1A
chr19_-_41222775 0.07 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
ADCK4
aarF domain containing kinase 4
chr16_+_12059050 0.07 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr17_-_46799872 0.07 ENST00000290294.3
PRAC1
prostate cancer susceptibility candidate 1
chr18_-_812517 0.07 ENST00000584307.1
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chrM_+_9207 0.07 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr17_+_7387677 0.07 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr7_-_33080506 0.06 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr18_-_812231 0.06 ENST00000314574.4
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr1_-_44497118 0.06 ENST00000537678.1
ENST00000466926.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr17_-_79885576 0.06 ENST00000574686.1
ENST00000357736.4
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr17_+_79373540 0.06 ENST00000307745.7
RP11-1055B8.7
BAH and coiled-coil domain-containing protein 1
chr6_-_100016678 0.06 ENST00000523799.1
ENST00000520429.1
CCNC
cyclin C
chr15_+_43425672 0.06 ENST00000260403.2
TMEM62
transmembrane protein 62
chr6_-_82462425 0.06 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr8_+_40018977 0.06 ENST00000520487.1
RP11-470M17.2
RP11-470M17.2
chr17_+_18380051 0.06 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
LGALS9C
lectin, galactoside-binding, soluble, 9C
chr3_+_159706537 0.06 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr2_+_85811525 0.06 ENST00000306384.4
VAMP5
vesicle-associated membrane protein 5
chr9_-_133814455 0.06 ENST00000448616.1
FIBCD1
fibrinogen C domain containing 1
chr9_-_77643307 0.06 ENST00000376834.3
ENST00000376830.3
C9orf41
chromosome 9 open reading frame 41
chr4_-_48782259 0.06 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL
FRY-like
chr10_+_71562180 0.06 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr15_+_74287118 0.06 ENST00000563500.1
PML
promyelocytic leukemia
chr2_-_160473114 0.06 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr6_+_139349817 0.06 ENST00000367660.3
ABRACL
ABRA C-terminal like
chr16_-_28518153 0.06 ENST00000356897.1
IL27
interleukin 27
chr11_-_47736896 0.05 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
AGBL2
ATP/GTP binding protein-like 2
chr2_-_106810742 0.05 ENST00000409501.3
ENST00000428048.2
ENST00000441952.1
ENST00000457835.1
ENST00000540130.1
UXS1
UDP-glucuronate decarboxylase 1
chrX_-_45710920 0.05 ENST00000456532.1
RP5-1158E12.3
RP5-1158E12.3
chr2_-_106810783 0.05 ENST00000283148.7
UXS1
UDP-glucuronate decarboxylase 1
chr5_-_61699698 0.05 ENST00000506390.1
ENST00000199320.4
DIMT1
DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
chr15_-_30113676 0.05 ENST00000400011.2
TJP1
tight junction protein 1
chr5_-_95297678 0.05 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr7_-_150779995 0.05 ENST00000462940.1
ENST00000492838.1
ENST00000392818.3
ENST00000488752.1
ENST00000476627.1
TMUB1
transmembrane and ubiquitin-like domain containing 1
chr6_-_94129244 0.05 ENST00000369303.4
ENST00000369297.1
EPHA7
EPH receptor A7
chr11_+_72983246 0.05 ENST00000393590.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr18_+_3466248 0.05 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chrX_+_65382433 0.05 ENST00000374727.3
HEPH
hephaestin
chr2_+_32390925 0.05 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
SLC30A6
solute carrier family 30 (zinc transporter), member 6
chr2_-_112642267 0.05 ENST00000341068.3
ANAPC1
anaphase promoting complex subunit 1
chr2_-_74753332 0.05 ENST00000451518.1
ENST00000404568.3
DQX1
DEAQ box RNA-dependent ATPase 1
chr12_-_99548645 0.05 ENST00000549025.2
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr9_-_90589402 0.05 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
CDK20
cyclin-dependent kinase 20
chr1_+_179050512 0.05 ENST00000367627.3
TOR3A
torsin family 3, member A
chr15_+_83478370 0.05 ENST00000286760.4
WHAMM
WAS protein homolog associated with actin, golgi membranes and microtubules
chr12_-_104350898 0.05 ENST00000552940.1
ENST00000547975.1
ENST00000549478.1
ENST00000546540.1
ENST00000546819.1
ENST00000378090.4
ENST00000547945.1
C12orf73
chromosome 12 open reading frame 73
chr2_-_74753305 0.05 ENST00000393951.2
DQX1
DEAQ box RNA-dependent ATPase 1
chr16_-_88851618 0.05 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr11_-_19082216 0.04 ENST00000329773.2
MRGPRX2
MAS-related GPR, member X2
chr4_-_88141615 0.04 ENST00000545252.1
ENST00000425278.2
ENST00000498875.2
KLHL8
kelch-like family member 8
chr1_+_179051160 0.04 ENST00000367625.4
ENST00000352445.6
TOR3A
torsin family 3, member A
chr10_+_15139330 0.04 ENST00000378202.5
ENST00000378197.4
RPP38
ribonuclease P/MRP 38kDa subunit
chr13_-_100624012 0.04 ENST00000267294.4
ZIC5
Zic family member 5
chr2_-_7005785 0.04 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr6_-_88411911 0.04 ENST00000257787.5
AKIRIN2
akirin 2
chr3_-_46037299 0.04 ENST00000296137.2
FYCO1
FYVE and coiled-coil domain containing 1
chr2_+_124782857 0.04 ENST00000431078.1
CNTNAP5
contactin associated protein-like 5
chr12_+_62654119 0.04 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr17_+_4643337 0.04 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr9_+_33265011 0.04 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr1_-_168464875 0.04 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr13_+_98794810 0.04 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr19_+_42300548 0.04 ENST00000344550.4
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr3_-_151176497 0.04 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr1_-_53018654 0.04 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11
zinc finger, CCHC domain containing 11
chr2_-_75937994 0.04 ENST00000409857.3
ENST00000470503.1
ENST00000541687.1
ENST00000442309.1
GCFC2
GC-rich sequence DNA-binding factor 2
chr10_+_121410882 0.04 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr12_+_70133152 0.04 ENST00000550536.1
ENST00000362025.5
RAB3IP
RAB3A interacting protein
chr1_+_110993795 0.04 ENST00000271331.3
PROK1
prokineticin 1
chr19_+_18942761 0.04 ENST00000599848.1
UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr15_-_65117807 0.04 ENST00000559239.1
ENST00000268043.4
ENST00000333425.6
PIF1
PIF1 5'-to-3' DNA helicase
chr2_-_197664366 0.03 ENST00000409364.3
ENST00000263956.3
GTF3C3
general transcription factor IIIC, polypeptide 3, 102kDa
chr19_+_36705504 0.03 ENST00000456324.1
ZNF146
zinc finger protein 146
chr12_+_4758264 0.03 ENST00000266544.5
NDUFA9
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.1 GO:1902003 regulation of beta-amyloid formation(GO:1902003)
0.1 0.5 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.3 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.3 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.9 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1 0.2 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 0.2 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.4 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.2 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.1 GO:0002857 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.4 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.4 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0034165 regulation of toll-like receptor 9 signaling pathway(GO:0034163) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.1 GO:0019541 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 4.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.0 0.1 GO:0001172 transcription, RNA-templated(GO:0001172)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.0 GO:0032899 regulation of neurotrophin production(GO:0032899)
0.0 0.1 GO:0030578 PML body organization(GO:0030578)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0051005 nerve growth factor signaling pathway(GO:0038180) negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.7 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.0 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 2.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions