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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 2.677

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_203208064	4.451	NM_173511	FAM117B	family with sequence similarity 117, member B
chr20_+_30409649	4.348	NM_001164603 NM_015338	ASXL1	additional sex combs like 1 (Drosophila)
chr18_+_75760434	4.035
chr6_+_43846735	4.030		VEGFA	vascular endothelial growth factor A
chr2_+_203208456	3.635		FAM117B	family with sequence similarity 117, member B
chr5_+_151131655	3.280	NM_005754 NM_198395	G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr17_+_69939806	3.272		GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr5_+_151131709	3.162		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151131853	3.052		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151131707	3.042		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151131704	2.938		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151131676	2.782		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr20_+_30410447	2.599		ASXL1	additional sex combs like 1 (Drosophila)
chr20_+_41519947	2.472		SRSF6	serine/arginine-rich splicing factor 6
chr17_+_69939130	2.436	NM_022036	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr8_+_126079929	2.384		SQLE	squalene epoxidase
chr2_+_203207912	2.246		FAM117B	family with sequence similarity 117, member B
chr2_+_26110232	1.979	NM_016131	RAB10	RAB10, member RAS oncogene family
chr10_-_105442868	1.959		SH3PXD2A	SH3 and PX domains 2A
chr20_+_11819364	1.946	NM_181443	BTBD3	BTB (POZ) domain containing 3
chr2_+_200879656	1.931		SPATS2L	spermatogenesis associated, serine-rich 2-like
chr2_+_219283751	1.845	NM_014640	TTLL4	tubulin tyrosine ligase-like family, member 4
chr8_+_126079900	1.835	NM_003129	SQLE	squalene epoxidase
chr6_-_163754903	1.826		LOC100526820	hypothetical LOC100526820
chr2_+_200879737	1.820		SPATS2L	spermatogenesis associated, serine-rich 2-like
chr3_+_57969127	1.819	NM_001164317 NM_001164318 NM_001164319 NM_001457	FLNB	filamin B, beta
chr8_+_126511739	1.805	NM_025195	TRIB1	tribbles homolog 1 (Drosophila)
chr2_-_219141199	1.796	NM_020935	USP37	ubiquitin specific peptidase 37
chr19_+_1358531	1.778	NM_018959 NM_170711	DAZAP1	DAZ associated protein 1
chr16_+_31098963	1.760		FUS	fused in sarcoma
chr19_+_748444	1.751		PTBP1	polypyrimidine tract binding protein 1
chrX_+_152608159	1.744	NM_001142806	SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr18_+_53253775	1.741	NM_004852	ONECUT2	one cut homeobox 2
chr19_+_748452	1.734		PTBP1	polypyrimidine tract binding protein 1
chr16_+_31098971	1.734		FUS	fused in sarcoma
chr16_+_31098962	1.704		FUS	fused in sarcoma
chr2_+_118562499	1.703	NM_016133	INSIG2	insulin induced gene 2
chr16_+_31098931	1.697	NM_001170634 NM_001170937 NM_004960	FUS	fused in sarcoma
chr19_+_748448	1.694		PTBP1	polypyrimidine tract binding protein 1
chr20_+_31541441	1.692		CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr2_+_26110487	1.688		RAB10	RAB10, member RAS oncogene family
chr16_+_31098959	1.686		FUS	fused in sarcoma
chr1_+_61320213	1.677	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr2_+_152900076	1.607		FMNL2	formin-like 2
chr11_+_809563	1.577		PNPLA2	patatin-like phospholipase domain containing 2
chr20_+_34143983	1.546		EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr2_+_28971007	1.522	NM_015131	WDR43	WD repeat domain 43
chr6_-_48144344	1.501	NM_001013732 NM_207499	C6orf138	chromosome 6 open reading frame 138
chr1_+_968522	1.464		AGRN	agrin
chr2_+_219141546	1.449		RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr2_+_219991342	1.420	NM_001927	DES	desmin
chr20_-_44370537	1.409		CDH22	cadherin 22, type 2
chr20_+_20296744	1.376	NM_002196	INSM1	insulinoma-associated 1
chr2_+_71412348	1.371	NM_001014972 NM_014497	ZNF638	zinc finger protein 638
chr2_+_223433919	1.370	NM_004457 NM_203372	ACSL3	acyl-CoA synthetase long-chain family member 3
chr1_+_44643513	1.370	NM_018150	RNF220	ring finger protein 220
chr20_+_34635362	1.367	NM_021809	TGIF2	TGFB-induced factor homeobox 2
chr10_+_101079099	1.363		CNNM1	cyclin M1
chr2_+_200879040	1.335	NM_001100422 NM_001100424 NM_001100423	SPATS2L	spermatogenesis associated, serine-rich 2-like
chr2_+_26110888	1.333		RAB10	RAB10, member RAS oncogene family
chr20_+_21231921	1.331	NM_012255	XRN2	5'-3' exoribonuclease 2
chr10_-_60606195	1.324
chr20_+_41519882	1.301	NM_006275	SRSF6	serine/arginine-rich splicing factor 6
chr14_-_22840249	1.299
chr2_-_213111525	1.292	NM_001042599 NM_005235	ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr2_+_20510312	1.282	NM_004040	RHOB	ras homolog gene family, member B
chr3_+_195336625	1.275	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr15_+_50098730	1.271		MAPK6	mitogen-activated protein kinase 6
chr2_+_232281491	1.262		PTMA	prothymosin, alpha
chr3_+_195336631	1.240		HES1	hairy and enhancer of split 1, (Drosophila)
chr7_+_150414704	1.240	NM_001042535 NM_031946	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr11_+_809696	1.238		PNPLA2	patatin-like phospholipase domain containing 2
chr16_-_85099941	1.237		LOC400550	hypothetical LOC400550
chr20_+_31541565	1.234	NM_001032999	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr20_+_60130866	1.228	NM_144703	LSM14B	LSM14B, SCD6 homolog B (S. cerevisiae)
chr2_+_86521999	1.218	NM_001146688	KDM3A	lysine (K)-specific demethylase 3A
chr2_+_86521939	1.215		KDM3A	lysine (K)-specific demethylase 3A
chr17_+_52517529	1.212	NM_003488	AKAP1	A kinase (PRKA) anchor protein 1
chr16_+_31378319	1.199		ARMC5	armadillo repeat containing 5
chr15_+_50098724	1.194		MAPK6	mitogen-activated protein kinase 6
chr14_+_32478209	1.192	NM_001164749 NM_001165893 NM_022123 NM_173159	NPAS3	neuronal PAS domain protein 3
chr2_+_219283928	1.189		TTLL4	tubulin tyrosine ligase-like family, member 4
chr19_+_1358664	1.183		DAZAP1	DAZ associated protein 1
chr19_+_748390	1.180	NM_002819 NM_031990 NM_031991 NM_175847	PTBP1	polypyrimidine tract binding protein 1
chr17_+_67628763	1.180		SOX9	SRY (sex determining region Y)-box 9
chr4_+_129950222	1.178	NM_024900 NM_199320	PHF17	PHD finger protein 17
chr1_+_148603613	1.176	NM_015203	RPRD2	regulation of nuclear pre-mRNA domain containing 2
chr2_+_96845704	1.156	NM_017623 NM_199078	CNNM3	cyclin M3
chr14_+_23590939	1.149	NM_138360	LRRC16B	leucine rich repeat containing 16B
chr12_+_6513865	1.143	NM_002046	GAPDH	glyceraldehyde-3-phosphate dehydrogenase
chr2_+_236068029	1.143		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr2_+_73294852	1.128	NM_006062	SMYD5	SMYD family member 5
chr10_+_114699953	1.110	NM_001146274 NM_001146283 NM_001146284 NM_001146285 NM_001146286 NM_001198525 NM_001198526 NM_001198527 NM_001198528 NM_001198529 NM_001198530 NM_001198531 NM_030756	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr10_+_60606352	1.100	NM_032439	PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like
chr10_+_104394185	1.091	NM_030912	TRIM8	tripartite motif containing 8
chr11_+_17714070	1.090	NM_001112741 NM_004976	KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1
chr2_+_32435550	1.083	NM_016252	BIRC6	baculoviral IAP repeat containing 6
chr10_+_114700775	1.076		TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr17_+_67628749	1.063	NM_000346	SOX9	SRY (sex determining region Y)-box 9
chr20_-_33335703	1.055		EIF6	eukaryotic translation initiation factor 6
chr9_+_33015270	1.044		DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1
chr2_+_32435800	1.041		BIRC6	baculoviral IAP repeat containing 6
chr14_+_73073570	1.037	NM_001037161	ACOT1	acyl-CoA thioesterase 1
chr16_+_2742657	1.032		SRRM2	serine/arginine repetitive matrix 2
chr20_+_35964912	1.026	NM_080607	VSTM2L	V-set and transmembrane domain containing 2 like
chr10_+_101078784	1.015	NM_020348	CNNM1	cyclin M1
chr2_+_86800940	1.012		RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr16_+_2742677	1.011		SRRM2	serine/arginine repetitive matrix 2
chr16_+_2742635	1.006		SRRM2	serine/arginine repetitive matrix 2
chr17_+_75366524	1.006	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr16_+_2742674	1.005		SRRM2	serine/arginine repetitive matrix 2
chr16_+_2742653	1.004		SRRM2	serine/arginine repetitive matrix 2
chr19_-_10202947	0.993	NM_004230	S1PR2	sphingosine-1-phosphate receptor 2
chr16_+_2742641	0.985		SRRM2	serine/arginine repetitive matrix 2
chr16_+_2742606	0.982		SRRM2	serine/arginine repetitive matrix 2
chr3_-_62334229	0.975	NM_018008	FEZF2	FEZ family zinc finger 2
chr17_-_37586716	0.973	NM_012285	KCNH4	potassium voltage-gated channel, subfamily H (eag-related), member 4
chr20_+_5934964	0.969		CRLS1	cardiolipin synthase 1
chr17_+_41327662	0.965		MAPT	microtubule-associated protein tau
chr20_-_60360789	0.962		LAMA5	laminin, alpha 5
chr2_+_26422404	0.961	NM_033505	EPT1	ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr5_+_139761608	0.961		ANKHD1	ankyrin repeat and KH domain containing 1
chr1_+_148603208	0.960		RPRD2	regulation of nuclear pre-mRNA domain containing 2
chr2_+_236067687	0.955		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr6_+_1336077	0.954
chr9_+_33015287	0.952		DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1
chr16_+_2742684	0.951		SRRM2	serine/arginine repetitive matrix 2
chr16_+_2742704	0.944		SRRM2	serine/arginine repetitive matrix 2
chr2_+_26422495	0.943		EPT1	ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr1_+_1396975	0.941		ATAD3B	ATPase family, AAA domain containing 3B
chr16_-_31378083	0.938
chr5_+_139761634	0.937		ANKHD1-EIF4EBP3 ANKHD1	ANKHD1-EIF4EBP3 readthrough ankyrin repeat and KH domain containing 1
chr10_-_124758178	0.936	NM_022466	IKZF5	IKAROS family zinc finger 5 (Pegasus)
chr16_+_4361775	0.932	NM_138440	VASN	vasorin
chr17_+_41327792	0.932		MAPT	microtubule-associated protein tau
chr16_-_23371952	0.931	NM_153603	COG7	component of oligomeric golgi complex 7
chr16_+_2742709	0.930		SRRM2	serine/arginine repetitive matrix 2
chr20_+_5934560	0.929	NM_019095	CRLS1	cardiolipin synthase 1
chr1_+_148603769	0.922		RPRD2	regulation of nuclear pre-mRNA domain containing 2
chr2_+_60962228	0.922	NM_002908	REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr20_+_35964962	0.916		VSTM2L	V-set and transmembrane domain containing 2 like
chr1_+_61319976	0.916	NM_001145512	NFIA	nuclear factor I/A
chr5_+_139761579	0.915	NM_020690 NM_001197030 NM_017747 NM_017978 NM_024668	ANKHD1-EIF4EBP3 ANKHD1	ANKHD1-EIF4EBP3 readthrough ankyrin repeat and KH domain containing 1
chr14_+_34413157	0.913
chr1_+_153366559	0.912		EFNA1	ephrin-A1
chr3_+_30623376	0.911		TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr1_-_59020875	0.910		JUN	jun proto-oncogene
chr20_+_5934761	0.910		CRLS1	cardiolipin synthase 1
chr12_+_6514160	0.910		GAPDH	glyceraldehyde-3-phosphate dehydrogenase
chr1_+_1397021	0.896	NM_031921	ATAD3B	ATPase family, AAA domain containing 3B
chr12_+_6514228	0.889		GAPDH	glyceraldehyde-3-phosphate dehydrogenase
chr17_-_76622967	0.887		FLJ90757	hypothetical LOC440465
chr5_+_139761656	0.880		ANKHD1-EIF4EBP3 ANKHD1	ANKHD1-EIF4EBP3 readthrough ankyrin repeat and KH domain containing 1
chr2_+_60962206	0.878		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr16_-_69271428	0.877		MTSS1L	metastasis suppressor 1-like
chr16_+_28741873	0.875		ATXN2L	ataxin 2-like
chr16_-_49742651	0.872	NM_002968	SALL1	sal-like 1 (Drosophila)
chr6_-_119712596	0.872	NM_005907	MAN1A1	mannosidase, alpha, class 1A, member 1
chr17_-_44010543	0.868	NM_024015	HOXB4	homeobox B4
chr1_+_1397020	0.868
chr1_+_93070120	0.866	NM_000969	RPL5	ribosomal protein L5
chr14_-_64040072	0.863	NM_006977	ZBTB25	zinc finger and BTB domain containing 25
chr2_+_60962279	0.860		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr19_+_1358750	0.857		DAZAP1	DAZ associated protein 1
chr17_+_6495694	0.857	NM_001105520	C17orf100	chromosome 17 open reading frame 100
chr1_+_93070202	0.848		RPL5	ribosomal protein L5
chr20_+_60810610	0.847	NM_002531	NTSR1	neurotensin receptor 1 (high affinity)
chr1_+_93070186	0.843		RPL5	ribosomal protein L5
chr9_+_6403139	0.835	NM_152896	UHRF2	ubiquitin-like with PHD and ring finger domains 2
chr16_+_66676833	0.833		NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr10_+_104667991	0.827	NM_017649 NM_199076 NM_199077	CNNM2	cyclin M2
chr20_+_56900116	0.826	NM_001077488	GNAS	GNAS complex locus
chr18_-_33399601	0.823		CELF4	CUGBP, Elav-like family member 4
chr1_+_1360765	0.821	NM_022834 NM_199121	VWA1	von Willebrand factor A domain containing 1
chr10_+_124758391	0.820	NM_001609	ACADSB	acyl-CoA dehydrogenase, short/branched chain
chr16_+_28741908	0.820	NM_007245 NM_145714 NM_148414 NM_148415 NM_148416	ATXN2L	ataxin 2-like
chr4_+_158361185	0.819	NM_000826 NM_001083619 NM_001083620	GRIA2	glutamate receptor, ionotropic, AMPA 2
chr20_+_34523231	0.815	NM_001042486	DLGAP4	discs, large (Drosophila) homolog-associated protein 4
chr5_+_154115046	0.811		LARP1	La ribonucleoprotein domain family, member 1
chr17_+_76623540	0.811	NM_001144888 NM_006340 NM_017450 NM_017451	BAIAP2	BAI1-associated protein 2
chr14_+_23653745	0.810	NM_001163484	DCAF11	DDB1 and CUL4 associated factor 11
chr19_+_8292374	0.802	NM_001031	RPS28	ribosomal protein S28
chr17_+_18027538	0.795	NM_017758	ALKBH5	alkB, alkylation repair homolog 5 (E. coli)
chr1_+_225194622	0.794		ADCK3	aarF domain containing kinase 3
chr17_+_77453363	0.792	NM_148896	NPB	neuropeptide B
chr3_+_151013126	0.790	NM_007282 NM_183381	RNF13	ring finger protein 13
chr17_+_77289804	0.787		SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr6_+_108987703	0.785	NM_201559	FOXO3	forkhead box O3
chr15_+_50098700	0.785	NM_002748	MAPK6	mitogen-activated protein kinase 6
chr18_+_75724655	0.785	NM_012283	KCNG2	potassium voltage-gated channel, subfamily G, member 2
chr19_+_1358604	0.783		DAZAP1	DAZ associated protein 1
chr19_+_44589283	0.783		ZFP36	zinc finger protein 36, C3H type, homolog (mouse)
chr14_+_38805622	0.777		CTAGE5	CTAGE family, member 5
chr14_-_22634134	0.777		ACIN1	apoptotic chromatin condensation inducer 1
chr2_-_73313823	0.773	NM_032319	C2orf7	chromosome 2 open reading frame 7
chr20_-_33335919	0.769	NM_181468	EIF6	eukaryotic translation initiation factor 6
chr14_-_73296387	0.768		C14orf43	chromosome 14 open reading frame 43
chr14_+_99775032	0.764		YY1	YY1 transcription factor
chr2_+_135392857	0.761	NM_001241 NM_058241	CCNT2	cyclin T2
chr5_-_139761182	0.759

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.16	2.83e-20	GO:0009987	cellular process
1.39	1.08e-19	GO:0044260	cellular macromolecule metabolic process
1.68	1.12e-19	GO:0010467	gene expression
1.30	2.76e-19	GO:0044237	cellular metabolic process
1.52	2.11e-18	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45	5.51e-17	GO:0034641	cellular nitrogen compound metabolic process
1.64	5.98e-16	GO:0016070	RNA metabolic process
1.43	1.02e-15	GO:0006807	nitrogen compound metabolic process
1.55	2.11e-15	GO:0090304	nucleic acid metabolic process
1.32	3.18e-15	GO:0043170	macromolecule metabolic process
1.26	1.98e-14	GO:0044238	primary metabolic process
1.23	3.43e-14	GO:0008152	metabolic process
1.38	2.89e-12	GO:0060255	regulation of macromolecule metabolic process
1.22	1.07e-11	GO:0050794	regulation of cellular process
1.95	1.21e-11	GO:0051254	positive regulation of RNA metabolic process
1.88	1.47e-11	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.93	2.78e-11	GO:0010628	positive regulation of gene expression
1.75	3.15e-11	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.97	3.38e-11	GO:0045893	positive regulation of transcription, DNA-dependent
1.85	4.40e-11	GO:0051173	positive regulation of nitrogen compound metabolic process
1.54	6.73e-11	GO:0009059	macromolecule biosynthetic process
1.55	8.55e-11	GO:0034645	cellular macromolecule biosynthetic process
1.67	1.67e-10	GO:0010604	positive regulation of macromolecule metabolic process
1.63	1.72e-10	GO:0009893	positive regulation of metabolic process
1.32	1.84e-10	GO:0019222	regulation of metabolic process
1.72	6.25e-10	GO:0032774	RNA biosynthetic process
1.19	6.39e-10	GO:0050789	regulation of biological process
1.41	6.57e-10	GO:0009058	biosynthetic process
1.83	7.95e-10	GO:0010557	positive regulation of macromolecule biosynthetic process
1.77	9.53e-10	GO:0031328	positive regulation of cellular biosynthetic process
1.42	9.60e-10	GO:0044249	cellular biosynthetic process
1.76	9.72e-10	GO:0009891	positive regulation of biosynthetic process
2.06	1.09e-09	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.33	1.12e-09	GO:0080090	regulation of primary metabolic process
1.32	1.54e-09	GO:0031323	regulation of cellular metabolic process
1.63	1.72e-09	GO:0031325	positive regulation of cellular metabolic process
1.55	1.89e-09	GO:0007399	nervous system development
1.33	2.02e-09	GO:0007275	multicellular organismal development
1.18	2.11e-09	GO:0065007	biological regulation
1.39	7.43e-09	GO:0010468	regulation of gene expression
1.30	1.02e-08	GO:0032502	developmental process
1.37	1.28e-08	GO:0009889	regulation of biosynthetic process
1.37	1.51e-08	GO:0031326	regulation of cellular biosynthetic process
1.71	1.72e-08	GO:0006351	transcription, DNA-dependent
1.39	2.89e-08	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.38	6.53e-08	GO:0010556	regulation of macromolecule biosynthetic process
1.34	2.35e-07	GO:0048731	system development
1.79	2.36e-07	GO:0006396	RNA processing
1.38	3.16e-07	GO:0051252	regulation of RNA metabolic process
1.30	8.89e-07	GO:0048856	anatomical structure development
1.33	1.10e-06	GO:0048518	positive regulation of biological process
1.35	1.13e-06	GO:0048522	positive regulation of cellular process
1.33	2.35e-06	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37	3.54e-06	GO:0048523	negative regulation of cellular process
1.58	3.76e-06	GO:0009892	negative regulation of metabolic process
1.37	3.82e-06	GO:0006355	regulation of transcription, DNA-dependent
1.34	5.21e-06	GO:0044267	cellular protein metabolic process
1.35	5.88e-06	GO:0048519	negative regulation of biological process
1.57	2.36e-05	GO:0010605	negative regulation of macromolecule metabolic process
1.57	2.57e-05	GO:0022008	neurogenesis
1.30	2.95e-05	GO:0051171	regulation of nitrogen compound metabolic process
1.57	3.21e-05	GO:0031324	negative regulation of cellular metabolic process
1.75	3.74e-05	GO:0051253	negative regulation of RNA metabolic process
1.65	4.82e-05	GO:0009890	negative regulation of biosynthetic process
1.58	4.86e-05	GO:0048699	generation of neurons
1.75	5.10e-05	GO:0045892	negative regulation of transcription, DNA-dependent
1.35	6.07e-05	GO:0030154	cell differentiation
1.70	6.83e-05	GO:0010629	negative regulation of gene expression
1.69	7.16e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.64	9.28e-05	GO:0031327	negative regulation of cellular biosynthetic process
1.67	1.11e-04	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.30	1.33e-04	GO:0035270	endocrine system development
1.67	1.44e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.74	1.71e-04	GO:0007417	central nervous system development
1.62	1.83e-04	GO:0009790	embryo development
1.63	1.89e-04	GO:0045595	regulation of cell differentiation
1.64	2.01e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.33	2.87e-04	GO:0048869	cellular developmental process
1.29	2.92e-04	GO:0071842	cellular component organization at cellular level
1.28	3.27e-04	GO:0071841	cellular component organization or biogenesis at cellular level
1.92	4.18e-04	GO:0060284	regulation of cell development
1.52	4.40e-04	GO:0050793	regulation of developmental process
1.81	5.36e-04	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.81	5.54e-04	GO:0006397	mRNA processing
1.74	5.86e-04	GO:0048646	anatomical structure formation involved in morphogenesis
1.62	6.27e-04	GO:0007167	enzyme linked receptor protein signaling pathway
1.75	6.70e-04	GO:0023057	negative regulation of signaling
1.24	6.87e-04	GO:0016043	cellular component organization
1.34	8.04e-04	GO:0048513	organ development
1.78	9.21e-04	GO:0009968	negative regulation of signal transduction
1.23	1.17e-03	GO:0071840	cellular component organization or biogenesis
1.82	1.33e-03	GO:0007420	brain development
1.49	1.34e-03	GO:0048468	cell development
1.55	1.42e-03	GO:2000026	regulation of multicellular organismal development
1.73	1.50e-03	GO:0010648	negative regulation of cell communication
2.29	2.27e-03	GO:0045165	cell fate commitment
1.78	2.30e-03	GO:0009792	embryo development ending in birth or egg hatching
1.65	2.35e-03	GO:0016071	mRNA metabolic process
2.78	2.44e-03	GO:0021915	neural tube development
1.87	2.83e-03	GO:0048729	tissue morphogenesis
2.20	3.24e-03	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter
2.03	3.87e-03	GO:0043193	positive regulation of gene-specific transcription
1.24	4.48e-03	GO:0019538	protein metabolic process
1.80	5.11e-03	GO:0003006	developmental process involved in reproduction
1.84	5.30e-03	GO:0008380	RNA splicing
1.31	6.11e-03	GO:0006464	protein modification process
1.75	6.13e-03	GO:0043009	chordate embryonic development
2.12	6.85e-03	GO:0030900	forebrain development
1.75	7.97e-03	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.30	8.04e-03	GO:0043412	macromolecule modification
1.96	9.39e-03	GO:0002009	morphogenesis of an epithelium
1.88	1.03e-02	GO:0045596	negative regulation of cell differentiation
1.20	1.05e-02	GO:0023052	signaling
1.73	1.23e-02	GO:0048598	embryonic morphogenesis
1.34	1.48e-02	GO:0009653	anatomical structure morphogenesis
1.32	1.59e-02	GO:0023051	regulation of signaling
1.40	1.85e-02	GO:0051246	regulation of protein metabolic process
1.65	2.19e-02	GO:0032583	regulation of gene-specific transcription
2.17	2.30e-02	GO:0031016	pancreas development
1.73	2.65e-02	GO:0007389	pattern specification process
1.89	2.77e-02	GO:0003002	regionalization
1.34	2.87e-02	GO:0009966	regulation of signal transduction
1.81	3.04e-02	GO:0010608	posttranscriptional regulation of gene expression
1.50	3.06e-02	GO:0030182	neuron differentiation
2.68	3.15e-02	GO:0048638	regulation of developmental growth
1.39	3.16e-02	GO:0010646	regulation of cell communication
1.98	3.31e-02	GO:0048732	gland development
1.74	3.77e-02	GO:0051093	negative regulation of developmental process
1.53	4.22e-02	GO:0009887	organ morphogenesis
3.52	4.24e-02	GO:0030850	prostate gland development
1.39	4.39e-02	GO:0032268	regulation of cellular protein metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.16	7.08e-25	GO:0005622	intracellular
1.16	7.26e-24	GO:0044424	intracellular part
1.21	3.43e-19	GO:0043231	intracellular membrane-bounded organelle
1.21	5.57e-19	GO:0043227	membrane-bounded organelle
1.18	3.40e-18	GO:0043226	organelle
1.18	3.69e-18	GO:0043229	intracellular organelle
1.53	3.41e-17	GO:0031974	membrane-enclosed lumen
1.54	3.52e-17	GO:0043233	organelle lumen
1.54	3.62e-17	GO:0070013	intracellular organelle lumen
1.29	5.86e-17	GO:0005634	nucleus
1.60	1.91e-16	GO:0031981	nuclear lumen
1.52	8.16e-15	GO:0044428	nuclear part
1.66	1.12e-13	GO:0005654	nucleoplasm
1.24	2.24e-11	GO:0044446	intracellular organelle part
1.24	7.80e-11	GO:0044422	organelle part
1.16	3.22e-09	GO:0005737	cytoplasm
1.68	4.42e-07	GO:0044451	nucleoplasm part
1.24	1.90e-05	GO:0032991	macromolecular complex
1.16	3.04e-05	GO:0044444	cytoplasmic part
1.05	3.11e-05	GO:0044464	cell part
1.05	3.24e-05	GO:0005623	cell
1.69	6.35e-05	GO:0030529	ribonucleoprotein complex
2.02	2.57e-04	GO:0016604	nuclear body
1.29	7.50e-04	GO:0005829	cytosol
2.24	4.04e-03	GO:0016607	nuclear speck
2.50	7.50e-03	GO:0000790	nuclear chromatin
1.43	2.02e-02	GO:0031988	membrane-bounded vesicle
1.52	2.98e-02	GO:0005730	nucleolus
1.19	3.47e-02	GO:0043234	protein complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.14	3.60e-19	GO:0005488	binding
1.24	3.87e-18	GO:0005515	protein binding
1.39	2.27e-14	GO:0003676	nucleic acid binding
1.39	6.90e-09	GO:0000166	nucleotide binding
1.69	1.39e-08	GO:0003723	RNA binding
1.61	2.14e-08	GO:0030528	transcription regulator activity
1.56	9.20e-07	GO:0001071	nucleic acid binding transcription factor activity
1.56	9.20e-07	GO:0003700	sequence-specific DNA binding transcription factor activity
2.01	2.58e-06	GO:0016563	transcription activator activity
1.66	4.02e-06	GO:0043565	sequence-specific DNA binding
1.31	2.01e-05	GO:0003677	DNA binding
1.33	2.11e-04	GO:0035639	purine ribonucleoside triphosphate binding
1.79	3.27e-04	GO:0005525	GTP binding
1.32	4.22e-04	GO:0032553	ribonucleotide binding
1.32	4.22e-04	GO:0032555	purine ribonucleotide binding
1.31	6.85e-04	GO:0017076	purine nucleotide binding
1.74	1.12e-03	GO:0019001	guanyl nucleotide binding
1.74	1.12e-03	GO:0032561	guanyl ribonucleotide binding
3.02	1.35e-02	GO:0003743	translation initiation factor activity
2.05	2.07e-02	GO:0003714	transcription corepressor activity
1.68	3.50e-02	GO:0016564	transcription repressor activity