Motif ID: GFI1B.p2

Z-value: 1.092


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
GFI1B 8328 growth factor independent 1B transcription repressor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GFI1Bchr9_+_134843918-0.639.0e-03Click!


Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_28016182 4.867 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr7_-_27171673 2.715 NM_152739
HOXA9
homeobox A9
chr7_-_27171648 2.617 HOXA9
homeobox A9
chr6_+_12398514 2.295 NM_001168319
NM_001955
EDN1

endothelin 1

chr3_+_161040343 2.245 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr2_-_113259441 2.036 NM_000575
IL1A
interleukin 1, alpha
chr10_-_91001531 1.986 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr10_-_91001542 1.946 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr10_-_91001496 1.867 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr6_-_134540666 1.796 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr17_+_67628763 1.695 SOX9
SRY (sex determining region Y)-box 9
chr15_-_81744469 1.411 NM_001717
BNC1
basonuclin 1
chr17_+_67628772 1.390 SOX9
SRY (sex determining region Y)-box 9
chr17_-_53849929 1.298 NM_017763
RNF43
ring finger protein 43
chr17_-_1566223 1.279 C17orf91
chromosome 17 open reading frame 91
chr4_+_166468266 1.253 NM_001017369
NM_006745
SC4MOL

sterol-C4-methyl oxidase-like

chr5_+_66160359 1.229 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chrX_-_10548458 1.199 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr11_+_19328846 1.156 NM_001111018
NAV2
neuron navigator 2
chr1_+_27062215 1.117 NM_006142
SFN
stratifin
chr1_+_101474892 1.106 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr5_+_102229425 1.088 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr16_+_67778441 1.011 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr2_-_165133239 0.969 GRB14
growth factor receptor-bound protein 14
chr3_-_150578023 0.914 TM4SF1
transmembrane 4 L six family member 1
chr2_-_189752575 0.890 NM_000393
COL5A2
collagen, type V, alpha 2
chr1_+_218768423 0.794 MARK1
MAP/microtubule affinity-regulating kinase 1
chr5_+_109053034 0.766 NM_002372
MAN2A1
mannosidase, alpha, class 2A, member 1
chr17_+_67628749 0.749 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr2_-_113310796 0.732 NM_000576
IL1B
interleukin 1, beta
chr8_-_17624304 0.693 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr7_-_56069324 0.681 PSPH
phosphoserine phosphatase
chr16_+_8714326 0.680 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr1_+_101475149 0.677 S1PR1
sphingosine-1-phosphate receptor 1
chr3_-_159872960 0.677 NM_020169
LXN
latexin
chr4_+_169654742 0.652 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr1_-_79244948 0.638 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr4_+_154345039 0.632 NM_015271
TRIM2
tripartite motif containing 2
chr18_+_19706979 0.627 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr4_-_187114863 0.604 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr17_-_53849888 0.604 RNF43
ring finger protein 43
chr7_+_115952325 0.597 CAV1
caveolin 1, caveolae protein, 22kDa
chr1_-_151352587 0.594 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr2_+_101874809 0.584 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr4_-_186970366 0.582 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr1_-_17180659 0.575 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr7_-_115458064 0.568 TFEC
transcription factor EC
chr3_-_121295663 0.564 NM_001146156
NM_002093
GSK3B

glycogen synthase kinase 3 beta

chr2_+_234255322 0.560 NM_019077
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr21_-_26269298 0.557 APP
amyloid beta (A4) precursor protein
chr11_+_5667494 0.556 NM_006074
TRIM22
tripartite motif containing 22
chr2_+_101874765 0.546 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr10_-_91001566 0.536 NM_000235
NM_001127605
LIPA

lipase A, lysosomal acid, cholesterol esterase

chr3_+_161040439 0.534 SCHIP1
schwannomin interacting protein 1
chr6_-_166960690 0.532 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr18_+_3441589 0.532 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr6_-_47385605 0.530 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr19_+_11061037 0.528 NM_000527
NM_001195798
NM_001195799
NM_001195800
NM_001195802
NM_001195803
LDLR





low density lipoprotein receptor





chr11_-_117640407 0.525 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr3_+_134976965 0.525 TF
transferrin
chr1_+_66570363 0.520 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr4_-_40631397 0.510 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr8_-_17599438 0.507 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr12_-_14929991 0.506 NM_000900
NM_001190839
MGP

matrix Gla protein

chr18_+_45342398 0.496 NM_006033
LIPG
lipase, endothelial
chr21_-_46473143 0.478 NM_001001438
NM_001145436
NM_001145437
NM_002340
LSS



lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)



chr5_+_102229612 0.461 PAM
peptidylglycine alpha-amidating monooxygenase
chr18_+_27281729 0.452 NM_001944
DSG3
desmoglein 3
chr18_+_59295123 0.449 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chrX_+_100692071 0.436 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr3_+_160473729 0.433 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr20_+_33223434 0.430 NM_006404
PROCR
protein C receptor, endothelial
chrX_-_37916138 0.428 SRPX
sushi-repeat containing protein, X-linked
chr15_+_38296920 0.427 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr3_-_152517204 0.421 NM_023915
GPR87
G protein-coupled receptor 87
chr11_+_57285809 0.408 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001331
CTNND1












catenin (cadherin-associated protein), delta 1












chr12_+_55201854 0.407 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr2_+_183290912 0.404 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr12_-_8706746 0.403 MFAP5
microfibrillar associated protein 5
chr7_-_115458010 0.402 NM_001018058
NM_012252
TFEC

transcription factor EC

chr17_+_71232370 0.396 NM_001005619
ITGB4
integrin, beta 4
chr13_-_47885248 0.390 LPAR6
lysophosphatidic acid receptor 6
chr22_-_26645214 0.382 NM_012399
PITPNB
phosphatidylinositol transfer protein, beta
chr2_+_62754489 0.380 NM_001142615
EHBP1
EH domain binding protein 1
chr22_-_26645202 0.375 PITPNB
phosphatidylinositol transfer protein, beta
chr8_-_17624009 0.373 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr8_-_19584373 0.369 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr3_-_135231518 0.362 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr1_+_66570683 0.362 PDE4B
phosphodiesterase 4B, cAMP-specific
chr19_+_47416271 0.360 NM_133444
ZNF526
zinc finger protein 526
chr2_+_204440753 0.353 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr1_-_68470585 0.347 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr17_+_38306339 0.347 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr8_+_32623792 0.345 NM_013959
NRG1
neuregulin 1
chr1_+_157246305 0.336 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr3_-_18455207 0.334 NM_001131010
SATB1
SATB homeobox 1
chr21_+_33936494 0.329 NM_001001132
NM_003024
ITSN1

intersectin 1 (SH3 domain protein)

chr15_+_30721161 0.328 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr22_+_38903825 0.327 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr1_+_216585298 0.325 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr2_-_161058550 0.323 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr11_-_8849485 0.315 ST5
suppression of tumorigenicity 5
chr1_+_24713396 0.306 RCAN3
RCAN family member 3
chr8_-_93099040 0.304 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_+_46581290 0.304 NM_006915
RP2
retinitis pigmentosa 2 (X-linked recessive)
chr5_+_134237325 0.300 NM_024715
TXNDC15
thioredoxin domain containing 15
chr2_+_234245243 0.297 NM_021027
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr11_+_18244383 0.292 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr1_+_151223180 0.291 NM_005987
SPRR1A
small proline-rich protein 1A
chrX_+_46581368 0.290 RP2
retinitis pigmentosa 2 (X-linked recessive)
chr18_+_3402071 0.287 NM_174886
TGIF1
TGFB-induced factor homeobox 1
chr10_+_124141808 0.282 NM_021622
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_+_43539239 0.276 NM_005424
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr5_-_137099602 0.275 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr4_-_187114407 0.268 SORBS2
sorbin and SH3 domain containing 2
chr1_+_218768170 0.263 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr11_-_117640196 0.263 MPZL2
myelin protein zero-like 2
chr12_-_8706533 0.249 MFAP5
microfibrillar associated protein 5
chr13_-_47885653 0.244 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr3_-_188936941 0.243 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr4_+_6322459 0.239 NM_001145853
NM_006005
WFS1

Wolfram syndrome 1 (wolframin)

chr8_+_32698892 0.236 NM_001159996
NRG1
neuregulin 1
chrX_-_10605726 0.235 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr8_+_9990471 0.231 NM_001135671
MSRA
methionine sulfoxide reductase A
chr18_+_31488530 0.229 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr9_-_35105844 0.229 NM_025182
KIAA1539
KIAA1539
chr3_-_191522886 0.226 NM_021101
CLDN1
claudin 1
chrX_+_135106578 0.224 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr12_+_52960798 0.221 HNRNPA1L2
HNRNPA1
HNRNPA1P10
heterogeneous nuclear ribonucleoprotein A1-like 2
heterogeneous nuclear ribonucleoprotein A1
heterogeneous nuclear ribonucleoprotein A1 pseudogene 10
chr9_+_96561750 0.221 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr1_+_161027115 0.219 NM_016371
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr17_-_5330204 0.216 NM_016041
DERL2
Der1-like domain family, member 2
chrX_+_105823723 0.215 NM_024539
RNF128
ring finger protein 128
chr3_+_115040369 0.211 NM_017577
GRAMD1C
GRAM domain containing 1C
chr8_-_18710575 0.211 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr4_+_6322489 0.210 WFS1
Wolfram syndrome 1 (wolframin)
chr2_+_162908828 0.207 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chr8_+_26569709 0.204 DPYSL2
dihydropyrimidinase-like 2
chr19_-_4509471 0.200 NM_032108
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr12_-_55042793 0.195 NM_001638
APOF
apolipoprotein F
chrX_-_10761729 0.191 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr19_+_50141068 0.191 NM_000483
APOC2
apolipoprotein C-II
chr19_+_52973653 0.187 NM_003009
SEPW1
selenoprotein W, 1
chr4_-_186814852 0.186 SORBS2
sorbin and SH3 domain containing 2
chr4_-_102487649 0.183 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr11_-_58099884 0.182 NM_004811
LPXN
leupaxin
chr18_-_43821491 0.179 NM_001039360
ZBTB7C
zinc finger and BTB domain containing 7C
chr5_+_140241976 0.178 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr14_-_92284626 0.178 NM_001008530
NM_005606
LGMN

legumain

chr1_-_151866367 0.171 NM_001024212
S100A13
S100 calcium binding protein A13
chr22_+_36472201 0.170 TRIOBP
TRIO and F-actin binding protein
chr13_-_74799898 0.165 TBC1D4
TBC1 domain family, member 4
chr16_+_66836707 0.163 NM_012320
PLA2G15
phospholipase A2, group XV
chr19_+_11061146 0.161 LDLR
low density lipoprotein receptor
chr4_+_1273662 0.161 NM_001017405
NM_005882
MAEA

macrophage erythroblast attacher

chr2_-_165259334 0.160 COBLL1
COBL-like 1
chr22_+_36472176 0.159 NM_007032
NM_138632
TRIOBP

TRIO and F-actin binding protein

chr20_-_43919360 0.158 NM_005469
ACOT8
acyl-CoA thioesterase 8
chr5_+_140870881 0.153


chr22_-_40012115 0.151 RANGAP1
Ran GTPase activating protein 1
chr12_-_52960168 0.150 NM_012117
CBX5
chromobox homolog 5
chrY_+_13283595 0.150 TTTY15
testis-specific transcript, Y-linked 15 (non-protein coding)
chr1_+_67923331 0.148 NM_001924
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr5_+_140772691 0.147 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr3_+_143858428 0.147 NM_001172312
PLS1
plastin 1
chr6_-_31756119 0.146 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr2_+_112749617 0.146 NM_198581
ZC3H6
zinc finger CCCH-type containing 6
chrX_+_15428820 0.145 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr2_-_85969527 0.142 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr10_+_104525877 0.142 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr4_-_186815116 0.141 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr17_+_7753428 0.140 CHD3
chromodomain helicase DNA binding protein 3
chr4_+_3285671 0.139 NM_002926
NM_198229
RGS12

regulator of G-protein signaling 12

chr5_+_140709907 0.138 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr6_-_76022565 0.136 TMEM30A
transmembrane protein 30A
chr1_-_161380562 0.135 RGS5
regulator of G-protein signaling 5
chr19_-_56163815 0.134 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr9_-_122852356 0.134 NM_001735
C5
complement component 5
chr16_+_66836798 0.134 PLA2G15
phospholipase A2, group XV
chr6_+_154373323 0.133 NM_001145279
NM_001145280
NM_001145281
OPRM1


opioid receptor, mu 1


chr12_-_121767272 0.133 NM_006018
GPR109B
G protein-coupled receptor 109B
chr17_+_20712337 0.132


chr5_-_146813343 0.131 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chrX_+_101862297 0.131 NM_001142524
NM_001142525
NM_001142526
NM_001142527
NM_001142528
NM_030639
BHLHB9





basic helix-loop-helix domain containing, class B, 9





chr4_+_1273679 0.131 MAEA
macrophage erythroblast attacher
chr8_-_16094518 0.130 MSR1
macrophage scavenger receptor 1
chr18_-_3864252 0.130 DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr12_+_52960745 0.129 NM_002136
NM_031157
HNRNPA1

heterogeneous nuclear ribonucleoprotein A1

chrY_+_2769630 0.128 RPS4Y1
ribosomal protein S4, Y-linked 1
chrX_+_102770303 0.126 NM_001006640
TCEAL1
transcription elongation factor A (SII)-like 1
chr1_-_108032645 0.124 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr21_-_46473100 0.122 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr17_+_73694992 0.121 NM_001010982
NM_001145526
AFMID

arylformamidase

chr18_+_8707368 0.121 NM_015210
KIAA0802
KIAA0802
chr14_-_74669864 0.119 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr1_-_116184846 0.117 NM_001111061
NHLH2
nescient helix loop helix 2
chr15_+_97990705 0.114 NM_001130928
MEF2A
myocyte enhancer factor 2A
chr19_-_48815572 0.114 ZNF428
zinc finger protein 428
chrX_-_72351392 0.114 NM_021963
NAP1L2
nucleosome assembly protein 1-like 2
chrX_+_113724806 0.113 NM_000868
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.00 1.15e-02 GO:0006629 lipid metabolic process

Nothing significant found in compartment category.

Nothing significant found in function category.