Motif ID: ZNF238.p2

Z-value: 1.732


Transcription factors associated with ZNF238.p2:

Gene SymbolEntrez IDGene Name
ZNF238 10472 zinc finger protein 238

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF238chr1_+_2422811990.581.8e-02Click!


Activity profile for motif ZNF238.p2.

activity profile for motif ZNF238.p2


Sorted Z-values histogram for motif ZNF238.p2

Sorted Z-values for motif ZNF238.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF238.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_54070302 10.591 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr2_+_189547377 7.082 COL3A1
collagen, type III, alpha 1
chr2_+_189547323 6.976 NM_000090
COL3A1
collagen, type III, alpha 1
chr2_+_189547358 6.959 COL3A1
collagen, type III, alpha 1
chr12_+_13240987 5.131 EMP1
epithelial membrane protein 1
chr1_-_151784889 4.871 NM_002961
NM_019554
S100A4

S100 calcium binding protein A4

chr19_-_11166186 4.302 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr12_-_105056577 4.233 NUAK1
NUAK family, SNF1-like kinase, 1
chr2_-_162808123 4.103 NM_004460
FAP
fibroblast activation protein, alpha
chr12_-_102968044 3.610 NM_031302
GLT8D2
glycosyltransferase 8 domain containing 2
chr12_-_102967828 3.506 GLT8D2
glycosyltransferase 8 domain containing 2
chr4_+_47181987 3.314 NM_020453
ATP10D
ATPase, class V, type 10D
chrX_-_101658297 3.221 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr1_-_17179694 3.157 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr9_+_115303527 2.809 NM_130795
RGS3
regulator of G-protein signaling 3
chr1_-_154913712 2.632 NM_006617
NES
nestin
chr3_+_30622905 2.578 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr12_+_26239755 2.543 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr10_+_11246934 2.420 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr1_-_146398501 2.292 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr10_-_95231933 2.264 NM_013451
NM_133337
MYOF

myoferlin

chr17_+_58058774 2.257 MRC2
mannose receptor, C type 2
chrX_+_99785818 2.184 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr2_+_151922350 2.162 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_-_146543102 2.145


chr19_-_48866111 2.094 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chrX_+_99786044 2.081 SRPX2
sushi-repeat containing protein, X-linked 2
chr1_-_143232526 2.081 FAM91A2
family with sequence similarity 91, member A2
chr12_+_76749199 2.060 NM_014903
NAV3
neuron navigator 3
chr6_+_39868770 2.034 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr17_+_45488330 2.009 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr1_-_142535878 2.004 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr3_+_101694098 1.954 NM_018004
TMEM45A
transmembrane protein 45A
chr1_-_146543016 1.951


chr12_+_26239535 1.951 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr2_+_201182187 1.933 AOX1
aldehyde oxidase 1
chr3_-_191321601 1.883 NM_018192
LEPREL1
leprecan-like 1
chr3_+_101694244 1.879 TMEM45A
transmembrane protein 45A
chr1_-_142536082 1.862


chr17_+_45488356 1.847 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr8_+_1759502 1.832 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chrX_-_106905545 1.687 TSC22D3
TSC22 domain family, member 3
chr7_+_90063543 1.663 CDK14
cyclin-dependent kinase 14
chr12_-_15833383 1.519 EPS8
epidermal growth factor receptor pathway substrate 8
chr6_+_39868126 1.492 DAAM2
dishevelled associated activator of morphogenesis 2
chr21_+_29439768 1.492 C21orf7
chromosome 21 open reading frame 7
chr5_+_49998677 1.482 PARP8
poly (ADP-ribose) polymerase family, member 8
chr5_+_49998528 1.458 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr2_-_1727324 1.453 PXDN
peroxidasin homolog (Drosophila)
chrX_+_100220491 1.364 NM_021637
TMEM35
transmembrane protein 35
chr17_-_15109315 1.348 NM_000304
PMP22
peripheral myelin protein 22
chr1_-_199742871 1.293 NM_001193570
NM_004078
CSRP1

cysteine and glycine-rich protein 1

chrX_-_106905657 1.275 NM_198057
TSC22D3
TSC22 domain family, member 3
chrX_+_80344253 1.266 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr2_-_1727247 1.255 PXDN
peroxidasin homolog (Drosophila)
chr1_+_211190476 1.252 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr1_+_154291140 1.234 NM_001145264
NM_014017
LAMTOR2

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

chr16_-_63713466 1.230 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr14_+_64041257 1.227 ZBTB1
zinc finger and BTB domain containing 1
chr11_+_7463175 1.204 NM_198474
OLFML1
olfactomedin-like 1
chr3_+_30623376 1.204 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr22_+_36401558 1.203 NM_002305
LGALS1
lectin, galactoside-binding, soluble, 1
chr3_+_62280435 1.198 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr2_-_158439868 1.188 NM_001105
ACVR1
activin A receptor, type I
chr2_-_1727292 1.167 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr8_+_70541412 1.165 NM_001128204
NM_015170
SULF1

sulfatase 1

chr5_-_178704934 1.165 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr7_-_124192916 1.163 NM_005302
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr11_+_74950766 1.153 NM_001235
SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr11_+_10283171 1.143 NM_001124
ADM
adrenomedullin
chrX_-_34585287 1.112 NM_031442
TMEM47
transmembrane protein 47
chr1_-_199742864 1.104 CSRP1
cysteine and glycine-rich protein 1
chr16_-_63713485 1.084 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr11_-_104332631 1.054 NM_033306
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr19_-_47155340 1.043 NM_006423
RABAC1
Rab acceptor 1 (prenylated)
chr12_-_15833617 1.026 NM_004447
EPS8
epidermal growth factor receptor pathway substrate 8
chr3_+_69216747 1.017 NM_006407
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr14_+_93646831 1.013 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr17_+_74531820 1.009 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr7_-_151142858 0.981 NM_001040633
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr1_-_143232344 0.979 LOC728855
hypothetical LOC728855
chr1_-_199742841 0.976 CSRP1
cysteine and glycine-rich protein 1
chr12_-_46585032 0.951 NM_000376
NM_001017535
VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

chr17_+_58058783 0.951 MRC2
mannose receptor, C type 2
chr11_+_113815317 0.939 NM_015523
REXO2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr5_-_178705036 0.933 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr1_-_143232464 0.928


chr9_+_115396020 0.907 NM_144489
RGS3
regulator of G-protein signaling 3
chr1_-_143232275 0.900 LOC728855
hypothetical LOC728855
chr5_-_142764168 0.896 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr16_+_6009095 0.886 NM_001142333
NM_018723
RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chr11_+_74950893 0.882 SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr8_-_23233426 0.879 LOXL2
lysyl oxidase-like 2
chr5_-_150501393 0.874 NM_001193544
ANXA6
annexin A6
chr8_-_102029997 0.868 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr7_+_93862137 0.861 COL1A2
PLAG1
collagen, type I, alpha 2
pleiomorphic adenoma gene 1
chr3_+_185377341 0.822 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr19_+_11510578 0.798 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr11_+_46256130 0.797 CREB3L1
cAMP responsive element binding protein 3-like 1
chr14_-_60818263 0.784 NM_001017970
TMEM30B
transmembrane protein 30B
chr19_+_18529652 0.776 C19orf50
chromosome 19 open reading frame 50
chrX_-_10548458 0.734 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr12_-_53099269 0.730 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr19_+_18529571 0.719 NM_001171948
NM_001171949
NM_024069
C19orf50


chromosome 19 open reading frame 50


chr2_+_33213111 0.718 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr3_-_115585178 0.717 NM_001164342
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_90097384 0.715 NM_133503
DCN
decorin
chr2_+_234302511 0.711 NM_019093
UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A3
chr3_+_185377430 0.710 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr13_+_51933228 0.707 CKAP2
cytoskeleton associated protein 2
chr16_-_63713382 0.703 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr5_-_39460787 0.689 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr15_+_47502666 0.667 NM_002009
FGF7
fibroblast growth factor 7
chr12_+_1608672 0.665 NM_032642
WNT5B
wingless-type MMTV integration site family, member 5B
chr7_+_5609416 0.664 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr11_+_71578249 0.633 NM_016724
NM_016725
FOLR1

folate receptor 1 (adult)

chr14_+_64040979 0.623 NM_001123329
NM_014950
ZBTB1

zinc finger and BTB domain containing 1

chr10_+_31647425 0.613 ZEB1
zinc finger E-box binding homeobox 1
chr19_-_47155277 0.609 RABAC1
Rab acceptor 1 (prenylated)
chr11_+_1846478 0.603 NM_001013253
LSP1
lymphocyte-specific protein 1
chrX_-_77111790 0.599 NM_001029891
PGAM4
phosphoglycerate mutase family member 4
chr17_+_74531873 0.573 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr1_+_173111306 0.572 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr3_-_112796855 0.570 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr15_+_65205107 0.557 NM_001145102
SMAD3
SMAD family member 3
chr5_-_83052606 0.550 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr11_+_46255737 0.547 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr3_-_191321367 0.545 LEPREL1
leprecan-like 1
chr14_-_19090251 0.534 NM_001145442
POTEG
POTEM
POTE ankyrin domain family, member G
POTE ankyrin domain family, member M
chr19_+_55627971 0.523 NM_004533
MYBPC2
myosin binding protein C, fast type
chr7_+_154493478 0.523 NM_024012
HTR5A
5-hydroxytryptamine (serotonin) receptor 5A
chr4_+_114190233 0.515 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr5_-_39460687 0.511 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr13_-_32678142 0.510 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr5_+_40715778 0.507 NM_000958
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr12_-_53099203 0.502 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr22_-_35011703 0.495 MYH9
myosin, heavy chain 9, non-muscle
chr12_-_53099277 0.490 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr5_-_151046638 0.488 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr3_+_49034494 0.486 NDUFAF3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr21_-_38210531 0.484 NM_002240
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr3_-_52248071 0.480 TWF2
twinfilin, actin-binding protein, homolog 2 (Drosophila)
chr5_-_41906459 0.479 NM_000436
OXCT1
3-oxoacid CoA transferase 1
chr11_+_5574440 0.474 NM_001003818
NM_001198644
NM_001198645
NM_001003819
TRIM6


TRIM6-TRIM34
tripartite motif containing 6


TRIM6-TRIM34 readthrough
chr17_-_51164443 0.456 NM_001099640
TMEM100
transmembrane protein 100
chr19_-_50518072 0.456 NM_001824
CKM
creatine kinase, muscle
chr11_+_32068990 0.451 NM_002901
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr1_+_181422016 0.451 LAMC2
laminin, gamma 2
chr1_-_199742589 0.447 NM_001193571
CSRP1
cysteine and glycine-rich protein 1
chr4_+_157044296 0.434 NM_005651
TDO2
tryptophan 2,3-dioxygenase
chr5_+_140762551 0.434 NM_018921
NM_032089
PCDHGA9

protocadherin gamma subfamily A, 9

chr17_+_7732759 0.428 NM_001005273
NM_005852
CHD3

chromodomain helicase DNA binding protein 3

chr11_-_57092332 0.425 UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr1_-_238842071 0.422 NM_022469
GREM2
gremlin 2
chr12_+_111047676 0.419 NM_001143906
NM_006700
TRAFD1

TRAF-type zinc finger domain containing 1

chr21_+_46226072 0.418 NM_001848
COL6A1
collagen, type VI, alpha 1
chr20_+_17498507 0.405 NM_001011546
NM_006870
DSTN

destrin (actin depolymerizing factor)

chr1_+_53165576 0.392 SCP2
sterol carrier protein 2
chr7_+_100113664 0.370 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr2_+_131692393 0.370 NM_001083538
POTEE
POTE ankyrin domain family, member E
chr3_-_52248182 0.369 NM_007284
TWF2
twinfilin, actin-binding protein, homolog 2 (Drosophila)
chr12_-_54408391 0.369 CD63
CD63 molecule
chr12_+_111047742 0.368 TRAFD1
TRAF-type zinc finger domain containing 1
chr15_+_53398424 0.368 NM_004855
PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr13_-_29322159 0.367 UBL3
ubiquitin-like 3
chr17_-_64649608 0.367 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr1_-_201586872 0.362


chr5_+_140772691 0.358 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr15_+_60726801 0.356 NM_015059
TLN2
talin 2
chr18_+_7557313 0.356 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr2_-_16710551 0.350 NM_030797
FAM49A
family with sequence similarity 49, member A
chr14_+_95792299 0.347 NM_000710
BDKRB1
bradykinin receptor B1
chr5_+_162862808 0.344 NM_182796
MAT2B
methionine adenosyltransferase II, beta
chr2_-_235070431 0.328 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr3_+_49034050 0.328 NM_199069
NM_199070
NDUFAF3

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3

chr15_+_29406335 0.324 NM_015995
KLF13
Kruppel-like factor 13
chr14_+_77939845 0.322 NM_004796
NRXN3
neurexin 3
chr12_-_107257205 0.314 NM_001142343
NM_001142344
NM_004072
CMKLR1


chemokine-like receptor 1


chr11_+_32069183 0.313 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr4_+_154345039 0.310 NM_015271
TRIM2
tripartite motif containing 2
chr10_+_116843108 0.309 NM_207303
ATRNL1
attractin-like 1
chr10_+_6284845 0.298 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr6_-_36623223 0.296 NM_007271
STK38
serine/threonine kinase 38
chr10_-_27189898 0.294 ABI1
abl-interactor 1
chr11_+_111288686 0.291 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr8_+_79590890 0.286 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr6_+_163068991 0.284 NM_001080379
PACRG
PARK2 co-regulated
chr10_-_27189797 0.282 ABI1
abl-interactor 1
chr2_+_187173176 0.277 NM_001144999
ITGAV
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr1_-_85816520 0.277 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr13_+_96672705 0.272 MBNL2
muscleblind-like 2 (Drosophila)
chr10_-_27189995 0.270 NM_001012750
NM_001012751
NM_001012752
NM_001178116
NM_001178119
NM_001178120
NM_001178121
NM_001178122
NM_001178123
NM_001178124
NM_001178125
NM_005470
ABI1











abl-interactor 1











chr3_-_15814678 0.269 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr5_+_1854493 0.265 NM_004553
NDUFS6
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr10_-_69422391 0.265 HERC4
hect domain and RLD 4
chr1_+_144287368 0.252 PIAS3
protein inhibitor of activated STAT, 3
chr19_+_8384181 0.248 NM_001005415
NM_001005416
NM_016496
MARCH2


membrane-associated ring finger (C3HC4) 2


chr14_+_89934358 0.245 NM_001166106
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr7_+_141342147 0.245 NM_004668
MGAM
maltase-glucoamylase (alpha-glucosidase)
chr20_-_6051562 0.244 FERMT1
fermitin family member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.97 3.25e-02 GO:0009611 response to wounding

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.78 2.15e-04 GO:0005576 extracellular region
3.28 2.28e-04 GO:0005578 proteinaceous extracellular matrix
2.95 4.88e-04 GO:0031012 extracellular matrix
3.74 9.77e-03 GO:0043235 receptor complex
1.82 2.67e-02 GO:0044421 extracellular region part
2.84 3.86e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
7.31 3.31e-03 GO:0003823 antigen binding