Motif ID: ACUGGCC

Z-value: 0.481


Mature miRNA associated with seed ACUGGCC:

NamemiRBase Accession
hsa-miR-193a-3p MIMAT0000459
hsa-miR-193b-3p MIMAT0002819



Activity profile for motif ACUGGCC.

activity profile for motif ACUGGCC


Sorted Z-values histogram for motif ACUGGCC

Sorted Z-values for motif ACUGGCC



Network of associatons between targets according to the STRING database.



First level regulatory network of ACUGGCC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_183605200 0.532 ENST00000304685.4
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr1_+_182992545 0.383 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr3_-_124774802 0.376 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr6_-_29527702 0.362 ENST00000377050.4
UBD
ubiquitin D
chr11_-_115375107 0.357 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr15_-_61521495 0.335 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr12_+_94542459 0.332 ENST00000258526.4
PLXNC1
plexin C1
chr7_-_26904317 0.294 ENST00000345317.2
SKAP2
src kinase associated phosphoprotein 2
chr13_+_98794810 0.292 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_+_128563652 0.291 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr10_+_97515409 0.235 ENST00000371207.3
ENST00000543964.1
ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

chr22_-_39548627 0.234 ENST00000216133.5
CBX7
chromobox homolog 7
chr20_-_14318248 0.229 ENST00000378053.3
ENST00000341420.4
FLRT3

fibronectin leucine rich transmembrane protein 3

chr6_-_16761678 0.220 ENST00000244769.4
ENST00000436367.1
ATXN1

ataxin 1

chr3_-_123603137 0.211 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK



myosin light chain kinase



chr4_-_23891693 0.181 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_-_92351769 0.176 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr3_-_57199397 0.174 ENST00000296318.7
IL17RD
interleukin 17 receptor D
chr2_-_208030647 0.172 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr16_-_4166186 0.161 ENST00000294016.3
ADCY9
adenylate cyclase 9
chr6_+_86159821 0.145 ENST00000369651.3
NT5E
5'-nucleotidase, ecto (CD73)
chr10_+_70480963 0.143 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
CCAR1







cell division cycle and apoptosis regulator 1







chr10_+_89622870 0.138 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr6_-_75994536 0.137 ENST00000475111.2
ENST00000230461.6
TMEM30A

transmembrane protein 30A

chr8_-_57123815 0.136 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1


pleiomorphic adenoma gene 1


chr17_-_38020392 0.133 ENST00000346872.3
ENST00000439167.2
ENST00000377945.3
ENST00000394189.2
ENST00000377944.3
ENST00000377958.2
ENST00000535189.1
ENST00000377952.2
IKZF3







IKAROS family zinc finger 3 (Aiolos)







chr20_-_4982132 0.126 ENST00000338244.1
ENST00000424750.2
SLC23A2

solute carrier family 23 (ascorbic acid transporter), member 2

chr14_+_57046500 0.121 ENST00000261556.6
TMEM260
transmembrane protein 260
chr17_-_66287257 0.120 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr18_+_55711575 0.112 ENST00000356462.6
ENST00000400345.3
ENST00000589054.1
ENST00000256832.7
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase



chr1_+_183155373 0.106 ENST00000493293.1
ENST00000264144.4
LAMC2

laminin, gamma 2

chr3_+_132136331 0.105 ENST00000260818.6
DNAJC13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr2_+_204192942 0.099 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chr6_-_47277634 0.098 ENST00000296861.2
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr12_+_11802753 0.098 ENST00000396373.4
ETV6
ets variant 6
chr11_-_27494279 0.091 ENST00000379214.4
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr12_-_57030115 0.087 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
BAZ2A


bromodomain adjacent to zinc finger domain, 2A


chr8_-_93115445 0.084 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_38846101 0.078 ENST00000274276.3
OSMR
oncostatin M receptor
chr12_-_31744031 0.076 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr5_+_133861790 0.074 ENST00000395003.1
PHF15
jade family PHD finger 2
chr22_+_24666763 0.069 ENST00000437398.1
ENST00000421374.1
ENST00000314328.9
ENST00000541492.1
SPECC1L



sperm antigen with calponin homology and coiled-coil domains 1-like



chr2_-_161350305 0.068 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr13_+_111365602 0.068 ENST00000333219.7
ING1
inhibitor of growth family, member 1
chr11_-_46940074 0.059 ENST00000378623.1
ENST00000534404.1
LRP4

low density lipoprotein receptor-related protein 4

chr1_+_77333117 0.057 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr20_+_57226284 0.057 ENST00000458280.1
ENST00000355957.5
ENST00000361770.5
ENST00000312283.8
ENST00000412911.1
ENST00000359617.4
ENST00000371141.4
STX16






syntaxin 16






chrX_+_110339439 0.053 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr4_-_105416039 0.053 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr1_+_151584544 0.050 ENST00000458013.2
ENST00000368843.3
SNX27

sorting nexin family member 27

chr1_-_169863016 0.049 ENST00000367772.4
ENST00000367771.6
SCYL3

SCY1-like 3 (S. cerevisiae)

chr12_-_111021110 0.044 ENST00000354300.3
PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr18_+_46065393 0.042 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr1_+_203764742 0.040 ENST00000432282.1
ENST00000453771.1
ENST00000367214.1
ENST00000367212.3
ENST00000332127.4
ZC3H11A




zinc finger CCCH-type containing 11A




chr14_+_23775971 0.039 ENST00000250405.5
BCL2L2
BCL2-like 2
chr11_+_69455855 0.038 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr17_+_61699766 0.033 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
MAP3K3



mitogen-activated protein kinase kinase kinase 3



chr19_+_797392 0.032 ENST00000350092.4
ENST00000349038.4
ENST00000586481.1
ENST00000585535.1
PTBP1



polypyrimidine tract binding protein 1



chr15_+_64443905 0.031 ENST00000325881.4
SNX22
sorting nexin 22
chr1_-_67519782 0.028 ENST00000235345.5
SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr14_-_68283291 0.028 ENST00000555452.1
ENST00000347230.4
ZFYVE26

zinc finger, FYVE domain containing 26

chr11_-_77532050 0.028 ENST00000308488.6
RSF1
remodeling and spacing factor 1
chr22_+_40390930 0.027 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr5_+_172483347 0.027 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREBRF



CREB3 regulatory factor



chrX_-_47479246 0.027 ENST00000295987.7
ENST00000340666.4
SYN1

synapsin I

chr10_-_99052382 0.026 ENST00000466484.1
ENST00000358531.4
ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ARHGAP19

ARHGAP19-SLIT1


Rho GTPase activating protein 19

ARHGAP19-SLIT1 readthrough (NMD candidate)


chr3_-_52090461 0.023 ENST00000296483.6
ENST00000495880.1
DUSP7

dual specificity phosphatase 7

chr2_+_113931513 0.021 ENST00000245796.6
ENST00000441564.3
PSD4

pleckstrin and Sec7 domain containing 4

chr2_+_29204161 0.018 ENST00000379558.4
ENST00000403861.2
FAM179A

family with sequence similarity 179, member A

chr9_-_135819987 0.018 ENST00000298552.3
ENST00000403810.1
TSC1

tuberous sclerosis 1

chr20_+_42086525 0.017 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chrX_-_40594755 0.016 ENST00000324817.1
MED14
mediator complex subunit 14
chr10_-_38146510 0.015 ENST00000395867.3
ZNF248
zinc finger protein 248
chr11_-_124670550 0.014 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr2_-_69870835 0.014 ENST00000409085.4
ENST00000406297.3
AAK1

AP2 associated kinase 1

chr11_+_118307179 0.014 ENST00000534358.1
ENST00000531904.2
ENST00000389506.5
ENST00000354520.4
KMT2A



lysine (K)-specific methyltransferase 2A



chr9_+_115983808 0.014 ENST00000374210.6
ENST00000374212.4
SLC31A1

solute carrier family 31 (copper transporter), member 1

chr3_+_71803201 0.014 ENST00000304411.2
GPR27
G protein-coupled receptor 27
chr2_-_131850951 0.013 ENST00000409185.1
ENST00000389915.3
FAM168B

family with sequence similarity 168, member B

chr1_-_150552006 0.013 ENST00000307940.3
ENST00000369026.2
MCL1

myeloid cell leukemia sequence 1 (BCL2-related)

chr4_-_87281224 0.010 ENST00000395169.3
ENST00000395161.2
MAPK10

mitogen-activated protein kinase 10

chr3_-_128902729 0.009 ENST00000451728.2
ENST00000446936.2
ENST00000502976.1
ENST00000500450.2
ENST00000441626.2
CNBP




CCHC-type zinc finger, nucleic acid binding protein




chr17_+_61627814 0.008 ENST00000310827.4
ENST00000431926.1
ENST00000415273.2
DCAF7


DDB1 and CUL4 associated factor 7


chr7_-_143059845 0.005 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr2_+_48541776 0.005 ENST00000413569.1
ENST00000340553.3
FOXN2

forkhead box N2

chr11_+_33563821 0.005 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L


KIAA1549-like


chr12_-_42538657 0.005 ENST00000398675.3
GXYLT1
glucoside xylosyltransferase 1
chr17_+_48796905 0.004 ENST00000505658.1
ENST00000393227.2
ENST00000240304.1
ENST00000311571.3
ENST00000505619.1
ENST00000544170.1
ENST00000510984.1
LUC7L3






LUC7-like 3 (S. cerevisiae)






chr14_-_27066636 0.003 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
NOVA1




neuro-oncological ventral antigen 1




chr3_-_52312636 0.003 ENST00000296490.3
WDR82
WD repeat domain 82
chr16_+_56225248 0.002 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr22_-_32146106 0.001 ENST00000327423.6
ENST00000397493.2
ENST00000434485.1
ENST00000412743.1
PRR14L



proline rich 14-like



chr17_+_8213590 0.000 ENST00000361926.3
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr19_-_14629224 0.000 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0060318 definitive erythrocyte differentiation(GO:0060318)
0.0 0.4 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.2 GO:0060414 aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0045722 response to muscle activity(GO:0014850) positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0060292 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) long term synaptic depression(GO:0060292)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.4 GO:0043260 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0042405 nuclear RNA export factor complex(GO:0042272) nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.0 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)