Motif ID: AGCACCA

Z-value: 2.173


Mature miRNA associated with seed AGCACCA:

NamemiRBase Accession
hsa-miR-29a-3p MIMAT0000086
hsa-miR-29b-3p MIMAT0000100
hsa-miR-29c-3p MIMAT0000681



Activity profile for motif AGCACCA.

activity profile for motif AGCACCA


Sorted Z-values histogram for motif AGCACCA

Sorted Z-values for motif AGCACCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCACCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_94023873 5.847 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr2_+_189839046 5.725 ENST00000304636.3
ENST00000317840.5
COL3A1

collagen, type III, alpha 1

chr15_+_81071684 5.334 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199


KIAA1199


chr3_-_120170052 4.810 ENST00000295633.3
FSTL1
follistatin-like 1
chr7_+_130126012 4.423 ENST00000341441.5
MEST
mesoderm specific transcript
chr9_+_137533615 4.371 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chr15_-_48937982 4.346 ENST00000316623.5
FBN1
fibrillin 1
chr21_-_28338732 4.203 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr2_-_238323007 3.877 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chr1_-_103574024 3.865 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
COL11A1



collagen, type XI, alpha 1



chr2_-_190044480 3.847 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr2_-_1748214 3.575 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN


peroxidasin homolog (Drosophila)


chr16_+_55512742 3.530 ENST00000568715.1
ENST00000219070.4
MMP2

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

chr5_-_121413974 3.482 ENST00000231004.4
LOX
lysyl oxidase
chrY_+_15016725 3.385 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr17_-_48278983 3.368 ENST00000225964.5
COL1A1
collagen, type I, alpha 1
chr4_-_157892498 3.294 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr2_-_190927447 3.241 ENST00000260950.4
MSTN
myostatin
chr5_-_111093406 3.047 ENST00000379671.3
NREP
neuronal regeneration related protein
chr13_+_110959598 2.939 ENST00000360467.5
COL4A2
collagen, type IV, alpha 2
chr3_+_159557637 2.747 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr8_-_122653630 2.742 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr1_+_182992545 2.630 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr3_+_158991025 2.607 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr1_+_53068020 2.538 ENST00000361314.4
GPX7
glutathione peroxidase 7
chr5_-_122372354 2.531 ENST00000306442.4
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr21_-_39288743 2.520 ENST00000609713.1
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr8_-_23261589 2.472 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
LOXL2



lysyl oxidase-like 2



chr15_-_23932437 2.387 ENST00000331837.4
NDN
necdin, melanoma antigen (MAGE) family member
chr2_-_227664474 2.301 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr1_-_225840747 2.179 ENST00000366843.2
ENST00000366844.3
ENAH

enabled homolog (Drosophila)

chr10_-_735553 2.169 ENST00000280886.6
ENST00000423550.1
DIP2C

DIP2 disco-interacting protein 2 homolog C (Drosophila)

chr3_-_114790179 2.126 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr11_+_75273101 2.051 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
SERPINH1


serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)


chr16_-_10674528 2.001 ENST00000359543.3
EMP2
epithelial membrane protein 2
chr13_-_110959478 1.937 ENST00000543140.1
ENST00000375820.4
COL4A1

collagen, type IV, alpha 1

chr4_+_124320665 1.935 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr11_-_117186946 1.922 ENST00000313005.6
ENST00000528053.1
BACE1

beta-site APP-cleaving enzyme 1

chr1_-_68299130 1.821 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr22_-_36236265 1.671 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2




RNA binding protein, fox-1 homolog (C. elegans) 2




chr6_-_52441713 1.671 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr9_-_21335356 1.644 ENST00000359039.4
KLHL9
kelch-like family member 9
chr5_-_149535421 1.607 ENST00000261799.4
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr1_-_236228403 1.585 ENST00000366595.3
NID1
nidogen 1
chr2_-_162931052 1.579 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr6_+_39760783 1.577 ENST00000398904.2
ENST00000538976.1
DAAM2

dishevelled associated activator of morphogenesis 2

chr17_-_56032684 1.575 ENST00000577830.1
CUEDC1
CUE domain containing 1
chr19_+_48216600 1.551 ENST00000263277.3
ENST00000538399.1
EHD2

EH-domain containing 2

chr3_+_99357319 1.541 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1


collagen, type VIII, alpha 1


chr1_-_120612240 1.481 ENST00000256646.2
NOTCH2
notch 2
chr19_-_10121144 1.478 ENST00000264828.3
COL5A3
collagen, type V, alpha 3
chr16_-_70719925 1.407 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr1_+_236849754 1.376 ENST00000542672.1
ENST00000366578.4
ACTN2

actinin, alpha 2

chr8_+_26435359 1.356 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chrX_+_9754461 1.352 ENST00000380913.3
SHROOM2
shroom family member 2
chr1_-_17304771 1.342 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr17_-_15165854 1.308 ENST00000395936.1
ENST00000395938.2
PMP22

peripheral myelin protein 22

chr10_+_43633914 1.274 ENST00000374466.3
ENST00000374464.1
CSGALNACT2

chondroitin sulfate N-acetylgalactosaminyltransferase 2

chr3_-_79068594 1.257 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr11_-_86666427 1.251 ENST00000531380.1
FZD4
frizzled family receptor 4
chr7_+_116139424 1.246 ENST00000222693.4
CAV2
caveolin 2
chr1_+_213123915 1.211 ENST00000366968.4
ENST00000490792.1
VASH2

vasohibin 2

chr12_-_6451235 1.209 ENST00000440083.2
ENST00000162749.2
TNFRSF1A

tumor necrosis factor receptor superfamily, member 1A

chr10_+_102790980 1.189 ENST00000393459.1
ENST00000224807.5
SFXN3

sideroflexin 3

chr7_+_17338239 1.170 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chrX_-_51239425 1.163 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr5_-_157002775 1.148 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr7_+_106809406 1.146 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1



HMG-box transcription factor 1



chr12_+_13349650 1.120 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1



epithelial membrane protein 1



chr9_-_130639997 1.117 ENST00000373176.1
AK1
adenylate kinase 1
chr16_+_69221028 1.108 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr1_+_151030234 1.080 ENST00000368921.3
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr7_-_124405681 1.071 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr17_+_26662730 1.055 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr14_-_53417732 1.049 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2



fermitin family member 2



chr6_-_134639180 1.045 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr9_+_101705893 1.005 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr6_+_143929307 1.003 ENST00000427704.2
ENST00000305766.6
PHACTR2

phosphatase and actin regulator 2

chr10_-_33246722 1.000 ENST00000437302.1
ENST00000396033.2
ITGB1

integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

chr10_-_30024716 0.998 ENST00000375398.2
ENST00000375400.3
SVIL

supervillin

chr12_-_51477333 0.990 ENST00000228515.1
ENST00000548206.1
ENST00000546935.1
ENST00000548981.1
CSRNP2



cysteine-serine-rich nuclear protein 2



chr2_-_202316260 0.987 ENST00000332624.3
TRAK2
trafficking protein, kinesin binding 2
chr8_+_11141925 0.985 ENST00000221086.3
MTMR9
myotubularin related protein 9
chr10_+_80828774 0.968 ENST00000334512.5
ZMIZ1
zinc finger, MIZ-type containing 1
chr8_+_38614807 0.948 ENST00000330691.6
ENST00000348567.4
TACC1

transforming, acidic coiled-coil containing protein 1

chr2_+_109204909 0.929 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr8_-_119124045 0.905 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr9_+_131314859 0.905 ENST00000358161.5
ENST00000372731.4
ENST00000372739.3
SPTAN1


spectrin, alpha, non-erythrocytic 1


chr5_+_149887672 0.894 ENST00000261797.6
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr10_-_128077024 0.880 ENST00000368679.4
ENST00000368676.4
ENST00000448723.1
ADAM12


ADAM metallopeptidase domain 12


chr12_-_65146636 0.870 ENST00000418919.2
GNS
glucosamine (N-acetyl)-6-sulfatase
chr17_-_40575535 0.856 ENST00000357037.5
PTRF
polymerase I and transcript release factor
chr2_+_9346892 0.856 ENST00000281419.3
ENST00000315273.4
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr6_-_128841503 0.838 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK







protein tyrosine phosphatase, receptor type, K







chr2_-_96931679 0.833 ENST00000258439.3
ENST00000432959.1
TMEM127

transmembrane protein 127

chr9_+_35161998 0.827 ENST00000396787.1
ENST00000378495.3
ENST00000378496.4
UNC13B


unc-13 homolog B (C. elegans)


chr6_-_111804393 0.799 ENST00000368802.3
ENST00000368805.1
REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr19_+_709101 0.796 ENST00000338448.5
PALM
paralemmin
chr11_+_842808 0.793 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
TSPAN4


tetraspanin 4


chr1_+_87170247 0.791 ENST00000370558.4
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr1_-_244013384 0.790 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr5_-_137368708 0.789 ENST00000033079.3
FAM13B
family with sequence similarity 13, member B
chr12_+_3186521 0.777 ENST00000537971.1
ENST00000011898.5
TSPAN9

tetraspanin 9

chr1_+_218519577 0.774 ENST00000366930.4
ENST00000366929.4
TGFB2

transforming growth factor, beta 2

chrX_+_73641286 0.765 ENST00000587091.1
SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr14_+_23067146 0.757 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr10_-_62704005 0.756 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr5_-_146833485 0.751 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr6_-_110500905 0.745 ENST00000392587.2
WASF1
WAS protein family, member 1
chr14_-_77923897 0.740 ENST00000343765.2
ENST00000327028.4
ENST00000556412.1
ENST00000557466.1
ENST00000448935.2
ENST00000553888.1
ENST00000557658.1
VIPAS39






VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog






chrX_+_49687216 0.739 ENST00000376088.3
CLCN5
chloride channel, voltage-sensitive 5
chr12_-_81331697 0.739 ENST00000552864.1
LIN7A
lin-7 homolog A (C. elegans)
chr7_+_73442102 0.736 ENST00000445912.1
ENST00000252034.7
ELN

elastin

chr17_-_62658186 0.734 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr12_+_54332535 0.726 ENST00000243056.3
HOXC13
homeobox C13
chr8_+_1772132 0.704 ENST00000349830.3
ENST00000520359.1
ENST00000518288.1
ENST00000398560.1
ARHGEF10



Rho guanine nucleotide exchange factor (GEF) 10



chr14_-_55878538 0.703 ENST00000247178.5
ATG14
autophagy related 14
chr7_+_94285637 0.699 ENST00000482108.1
ENST00000488574.1
PEG10

paternally expressed 10

chr14_+_55034599 0.689 ENST00000392067.3
ENST00000357634.3
SAMD4A

sterile alpha motif domain containing 4A

chr1_+_203444887 0.687 ENST00000343110.2
PRELP
proline/arginine-rich end leucine-rich repeat protein
chr1_-_146644122 0.686 ENST00000254101.3
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr11_-_66336060 0.676 ENST00000310325.5
CTSF
cathepsin F
chr7_+_43152191 0.674 ENST00000395891.2
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr15_+_63334831 0.674 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
TPM1








tropomyosin 1 (alpha)








chr4_-_54930790 0.667 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr12_+_9067327 0.657 ENST00000433083.2
ENST00000544916.1
ENST00000544539.1
ENST00000539063.1
PHC1



polyhomeotic homolog 1 (Drosophila)



chr13_-_67804445 0.657 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
PCDH9


protocadherin 9


chrX_-_64196307 0.654 ENST00000545618.1
ZC4H2
zinc finger, C4H2 domain containing
chr5_-_176981417 0.637 ENST00000514747.1
ENST00000443375.2
ENST00000329540.5
FAM193B


family with sequence similarity 193, member B


chr12_-_69326940 0.633 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
CPM



carboxypeptidase M



chr14_-_80677970 0.601 ENST00000438257.4
DIO2
deiodinase, iodothyronine, type II
chr10_+_75757863 0.594 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
VCL


vinculin


chr2_+_148602058 0.581 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
ACVR2A


activin A receptor, type IIA


chr9_-_14314066 0.578 ENST00000397575.3
NFIB
nuclear factor I/B
chr4_-_85887503 0.577 ENST00000509172.1
ENST00000322366.6
ENST00000295888.4
ENST00000502713.1
WDFY3



WD repeat and FYVE domain containing 3



chr5_-_78281603 0.574 ENST00000264914.4
ARSB
arylsulfatase B
chr10_+_115438920 0.569 ENST00000429617.1
ENST00000369331.4
CASP7

caspase 7, apoptosis-related cysteine peptidase

chr9_+_112810878 0.567 ENST00000434623.2
ENST00000374525.1
AKAP2

A kinase (PRKA) anchor protein 2

chr11_+_117049445 0.560 ENST00000324225.4
ENST00000532960.1
SIDT2

SID1 transmembrane family, member 2

chr5_-_178772424 0.559 ENST00000251582.7
ENST00000274609.5
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr5_-_133304473 0.552 ENST00000231512.3
C5orf15
chromosome 5 open reading frame 15
chr5_+_153418466 0.548 ENST00000522782.1
ENST00000439768.2
ENST00000436816.1
ENST00000322602.5
ENST00000522177.1
ENST00000520899.1
MFAP3





microfibrillar-associated protein 3





chr19_+_34745442 0.546 ENST00000299505.6
ENST00000588470.1
ENST00000589583.1
ENST00000588338.2
KIAA0355



KIAA0355



chr14_-_90085458 0.540 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3


forkhead box N3


chr11_-_78052923 0.537 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr15_+_90808919 0.520 ENST00000379095.3
NGRN
neugrin, neurite outgrowth associated
chr11_+_57520715 0.517 ENST00000524630.1
ENST00000529919.1
ENST00000399039.4
ENST00000533189.1
CTNND1



catenin (cadherin-associated protein), delta 1



chr3_+_126707437 0.512 ENST00000393409.2
ENST00000251772.4
PLXNA1

plexin A1

chr10_+_11206925 0.507 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2


CUGBP, Elav-like family member 2


chr13_-_103451307 0.498 ENST00000376004.4
KDELC1
KDEL (Lys-Asp-Glu-Leu) containing 1
chr14_-_51562745 0.494 ENST00000298355.3
TRIM9
tripartite motif containing 9
chr20_+_3451650 0.489 ENST00000262919.5
ATRN
attractin
chr1_+_2160134 0.489 ENST00000378536.4
SKI
v-ski avian sarcoma viral oncogene homolog
chr1_-_155881156 0.485 ENST00000539040.1
ENST00000368323.3
RIT1

Ras-like without CAAX 1

chr16_+_3507985 0.481 ENST00000421765.3
ENST00000360862.5
ENST00000414063.2
ENST00000610180.1
ENST00000608993.1
NAA60


NAA60

N(alpha)-acetyltransferase 60, NatF catalytic subunit


N-alpha-acetyltransferase 60

chr2_-_240322643 0.478 ENST00000345617.3
HDAC4
histone deacetylase 4
chr3_+_137906109 0.473 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
ARMC8



armadillo repeat containing 8



chr7_+_128379346 0.469 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU





calumenin





chr15_-_76005170 0.468 ENST00000308508.5
CSPG4
chondroitin sulfate proteoglycan 4
chr9_+_112542572 0.466 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr2_+_173292301 0.465 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
ITGA6


integrin, alpha 6


chr20_+_30193083 0.456 ENST00000376112.3
ENST00000376105.3
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr20_+_30865429 0.448 ENST00000375712.3
KIF3B
kinesin family member 3B
chr11_-_101454658 0.446 ENST00000344327.3
TRPC6
transient receptor potential cation channel, subfamily C, member 6
chr9_-_37465396 0.443 ENST00000307750.4
ZBTB5
zinc finger and BTB domain containing 5
chrX_+_95939711 0.428 ENST00000373049.4
ENST00000324765.8
DIAPH2

diaphanous-related formin 2

chr16_-_71758602 0.426 ENST00000568954.1
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr16_+_66914264 0.423 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2




pyruvate dehyrogenase phosphatase catalytic subunit 2




chr1_+_203595903 0.417 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4


ATPase, Ca++ transporting, plasma membrane 4


chr17_-_3599327 0.416 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
P2RX5


purinergic receptor P2X, ligand-gated ion channel, 5


chr20_+_34700333 0.404 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr8_-_93115445 0.398 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_-_32345305 0.396 ENST00000302418.4
KIF5B
kinesin family member 5B
chr9_+_129567282 0.392 ENST00000449886.1
ENST00000373464.4
ENST00000450858.1
ZBTB43


zinc finger and BTB domain containing 43


chr5_+_177019159 0.390 ENST00000332598.6
TMED9
transmembrane emp24 protein transport domain containing 9
chr16_+_69599861 0.384 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr5_+_140560980 0.382 ENST00000361016.2
PCDHB16
protocadherin beta 16
chr6_-_80657292 0.382 ENST00000369816.4
ELOVL4
ELOVL fatty acid elongase 4
chr12_+_56915713 0.381 ENST00000262031.5
ENST00000552247.2
RBMS2

RNA binding motif, single stranded interacting protein 2

chr7_-_129592700 0.381 ENST00000472396.1
ENST00000355621.3
UBE2H

ubiquitin-conjugating enzyme E2H

chrX_-_106959631 0.378 ENST00000486554.1
ENST00000372390.4
TSC22D3

TSC22 domain family, member 3

chr5_+_157170703 0.368 ENST00000286307.5
LSM11
LSM11, U7 small nuclear RNA associated
chr11_-_60929074 0.368 ENST00000301765.5
VPS37C
vacuolar protein sorting 37 homolog C (S. cerevisiae)
chr10_-_111683183 0.366 ENST00000403138.2
ENST00000369683.1
XPNPEP1

X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

chr20_-_45035223 0.361 ENST00000450812.1
ENST00000290246.6
ENST00000439931.2
ENST00000396391.1
ELMO2



engulfment and cell motility 2



chr17_-_7297833 0.359 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3



TMEM256-PLSCR3 readthrough (NMD candidate)



chr5_+_65222299 0.348 ENST00000284037.5
ERBB2IP
erbb2 interacting protein
chr14_+_23775971 0.347 ENST00000250405.5
BCL2L2
BCL2-like 2
chr20_-_39928705 0.323 ENST00000436099.2
ENST00000309060.3
ENST00000373261.1
ENST00000436440.2
ENST00000540170.1
ENST00000557816.1
ENST00000560361.1
ZHX3






zinc fingers and homeoboxes 3






chr6_-_3227877 0.323 ENST00000259818.7
TUBB2B
tubulin, beta 2B class IIb
chr6_-_3157760 0.317 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr9_+_136325089 0.311 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1


calcium channel flower domain containing 1


chr19_+_19431490 0.308 ENST00000392313.6
ENST00000262815.8
ENST00000609122.1
MAU2


MAU2 sister chromatid cohesion factor


chr8_-_120651020 0.306 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2



ectonucleotide pyrophosphatase/phosphodiesterase 2



chr17_+_45727204 0.304 ENST00000290158.4
KPNB1
karyopherin (importin) beta 1
chr12_+_6493199 0.294 ENST00000228918.4
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr10_+_104535994 0.291 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr5_-_139726181 0.281 ENST00000507104.1
ENST00000230990.6
HBEGF

heparin-binding EGF-like growth factor

chr7_-_121036337 0.276 ENST00000426156.1
ENST00000359943.3
ENST00000412653.1
FAM3C


family with sequence similarity 3, member C


chr12_+_122516626 0.270 ENST00000319080.7
MLXIP
MLX interacting protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.7 GO:0070208 protein heterotrimerization(GO:0070208)
1.3 5.1 GO:0045112 integrin biosynthetic process(GO:0045112)
1.1 3.2 GO:0014889 muscle atrophy(GO:0014889) regulation of skeletal muscle tissue growth(GO:0048631)
0.8 19.1 GO:0030199 collagen fibril organization(GO:0030199)
0.8 2.3 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.5 1.6 GO:0008218 bioluminescence(GO:0008218)
0.5 4.2 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.5 4.3 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.5 0.5 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.5 1.4 GO:0007028 cytoplasm organization(GO:0007028)
0.4 1.3 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.4 1.3 GO:0061298 progesterone secretion(GO:0042701) retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.3 1.4 GO:0030035 microspike assembly(GO:0030035)
0.3 1.9 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.3 1.3 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.3 0.9 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.3 0.8 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.2 1.2 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) positive regulation of dopamine receptor signaling pathway(GO:0060161) caveola assembly(GO:0070836) membrane assembly(GO:0071709)
0.2 0.6 GO:0032927 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of activin receptor signaling pathway(GO:0032927) positive regulation of follicle-stimulating hormone secretion(GO:0046881) Sertoli cell proliferation(GO:0060011)
0.2 1.4 GO:0045176 apical protein localization(GO:0045176)
0.2 3.6 GO:0001960 negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.2 0.5 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.2 1.1 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.2 0.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.9 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.3 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 4.3 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.1 0.8 GO:0019985 translesion synthesis(GO:0019985)
0.1 1.4 GO:0051602 response to electrical stimulus(GO:0051602)
0.1 0.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.1 2.4 GO:0007413 axonal fasciculation(GO:0007413)
0.1 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.4 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1 0.8 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 2.7 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.3 GO:0032288 myelin assembly(GO:0032288)
0.1 0.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 1.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 1.5 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.7 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.7 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 0.7 GO:0003065 regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065)
0.1 1.7 GO:0032964 collagen biosynthetic process(GO:0032964)
0.1 0.3 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.3 GO:0008105 asymmetric protein localization(GO:0008105)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 0.5 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 0.6 GO:0051597 response to methylmercury(GO:0051597)
0.1 2.4 GO:0021987 cerebral cortex development(GO:0021987)
0.1 0.2 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 2.2 GO:0001843 neural tube closure(GO:0001843) primary neural tube formation(GO:0014020) tube closure(GO:0060606)
0.1 4.8 GO:0071772 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.1 2.2 GO:1901343 negative regulation of angiogenesis(GO:0016525) negative regulation of vasculature development(GO:1901343) negative regulation of blood vessel morphogenesis(GO:2000181)
0.1 3.5 GO:0007498 mesoderm development(GO:0007498)
0.1 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.9 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.7 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 1.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 1.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.2 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.0 0.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 1.0 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.1 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999)
0.0 0.2 GO:0051988 negative regulation of odontogenesis(GO:0042483) regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:1990170 detoxification of cadmium ion(GO:0071585) stress response to cadmium ion(GO:1990170)
0.0 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 1.5 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.5 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.2 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.3 GO:0046697 decidualization(GO:0046697)
0.0 0.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848)
0.0 0.9 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.3 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.8 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.4 GO:0003407 neural retina development(GO:0003407)
0.0 1.8 GO:0000910 cytokinesis(GO:0000910)
0.0 0.9 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0070245 positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 1.6 GO:0007569 cell aging(GO:0007569)
0.0 1.8 GO:0007588 excretion(GO:0007588)
0.0 0.1 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.1 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.7 GO:0097479 synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.0 GO:0006826 iron ion transport(GO:0006826)
0.0 0.5 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.3 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.8 GO:0001525 angiogenesis(GO:0001525)
0.0 0.7 GO:0030041 actin filament polymerization(GO:0030041)
0.0 1.9 GO:0007568 aging(GO:0007568)
0.0 0.7 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.1 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.5 GO:0001764 neuron migration(GO:0001764)
0.0 0.0 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.4 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 2.6 GO:0007517 muscle organ development(GO:0007517)
0.0 0.2 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0005588 collagen type V trimer(GO:0005588)
2.1 19.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.7 2.6 GO:0043260 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.6 2.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.5 2.3 GO:0005899 insulin receptor complex(GO:0005899)
0.5 4.6 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.4 5.7 GO:0001527 microfibril(GO:0001527)
0.3 1.6 GO:0071438 invadopodium membrane(GO:0071438)
0.3 3.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.0 GO:0071437 invadopodium(GO:0071437)
0.2 2.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.4 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 2.7 GO:0005581 collagen trimer(GO:0005581)
0.1 1.4 GO:0031941 filamentous actin(GO:0031941)
0.1 0.8 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 0.9 GO:0043218 compact myelin(GO:0043218)
0.1 1.3 GO:0031143 pseudopodium(GO:0031143)
0.1 0.2 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.1 0.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 4.5 GO:0042641 actomyosin(GO:0042641)
0.1 8.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.9 GO:0008091 spectrin(GO:0008091)
0.1 1.8 GO:0005884 actin filament(GO:0005884)
0.1 2.4 GO:0043204 perikaryon(GO:0043204)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 1.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 13.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0033655 host(GO:0018995) host cell cytoplasm(GO:0030430) host cell part(GO:0033643) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.8 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.8 GO:0005776 autophagosome(GO:0005776)
0.0 2.7 GO:0030027 lamellipodium(GO:0030027)
0.0 2.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.2 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.4 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.5 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 23.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.2 3.6 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.8 2.3 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.5 2.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5 1.4 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.5 6.0 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.3 1.3 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.3 0.9 GO:0043199 sulfate binding(GO:0043199)
0.3 2.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.3 2.6 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 1.2 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.2 0.9 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 2.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 2.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 1.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.6 GO:0016362 activin receptor activity, type II(GO:0016362)
0.2 15.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 3.2 GO:0043498 obsolete cell surface binding(GO:0043498)
0.2 1.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.8 GO:0008242 omega peptidase activity(GO:0008242)
0.1 2.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.7 GO:0042301 phosphate ion binding(GO:0042301)
0.1 0.5 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.1 2.2 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.1 1.5 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 1.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.4 GO:0004741 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.5 GO:0031420 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.1 0.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.7 GO:0030371 translation repressor activity(GO:0030371)
0.1 1.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 8.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.8 GO:0050780 dopamine receptor binding(GO:0050780)
0.1 1.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 5.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 2.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 2.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 4.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0050833 pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 1.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.4 GO:0017069 snRNA binding(GO:0017069)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 2.2 GO:0008194 UDP-glycosyltransferase activity(GO:0008194)
0.0 3.3 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.2 GO:0004691 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 2.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.7 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.