Motif ID: AGCAGCA

Z-value: 1.362


Mature miRNA associated with seed AGCAGCA:

NamemiRBase Accession
hsa-miR-15a-5p MIMAT0000068
hsa-miR-15b-5p MIMAT0000417
hsa-miR-16-5p MIMAT0000069
hsa-miR-195-5p MIMAT0000461
hsa-miR-424-5p MIMAT0001341
hsa-miR-497-5p MIMAT0002820
hsa-miR-6838-5p MIMAT0027578



Activity profile for motif AGCAGCA.

activity profile for motif AGCAGCA


Sorted Z-values histogram for motif AGCAGCA

Sorted Z-values for motif AGCAGCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCAGCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_63328817 2.047 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr11_-_115375107 2.020 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr7_-_103629963 1.990 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN


reelin


chr12_+_66217911 1.941 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr1_-_92351769 1.819 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr2_+_110371905 1.665 ENST00000356454.3
SOWAHC
sosondowah ankyrin repeat domain family member C
chr6_+_107811162 1.573 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr12_-_8088871 1.565 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr9_+_470288 1.502 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr14_+_32546485 1.417 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5


Rho GTPase activating protein 5


chr12_-_8025442 1.400 ENST00000340749.5
ENST00000535295.1
ENST00000539234.1
SLC2A14


solute carrier family 2 (facilitated glucose transporter), member 14


chr10_-_52645416 1.293 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF





APOBEC1 complementation factor





chr3_-_129407535 1.285 ENST00000432054.2
TMCC1
transmembrane and coiled-coil domain family 1
chr1_+_10271674 1.259 ENST00000377086.1
KIF1B
kinesin family member 1B
chr11_-_86666427 1.232 ENST00000531380.1
FZD4
frizzled family receptor 4
chrX_-_20284958 1.216 ENST00000379565.3
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr2_-_166930131 1.215 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chr5_-_141704566 1.195 ENST00000344120.4
ENST00000434127.2
SPRY4

sprouty homolog 4 (Drosophila)

chr17_-_56494713 1.194 ENST00000407977.2
RNF43
ring finger protein 43
chr20_+_34700333 1.194 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr16_+_57406368 1.147 ENST00000006053.6
ENST00000563383.1
CX3CL1

chemokine (C-X3-C motif) ligand 1

chr9_-_112083229 1.095 ENST00000374566.3
ENST00000374557.4
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr6_+_37137939 1.085 ENST00000373509.5
PIM1
pim-1 oncogene
chr8_+_56014949 1.081 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr3_+_38495333 1.062 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr5_+_52285144 1.052 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr16_-_73082274 1.048 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr17_-_80056099 1.034 ENST00000306749.2
FASN
fatty acid synthase
chr18_+_60190226 1.000 ENST00000269499.5
ZCCHC2
zinc finger, CCHC domain containing 2
chr1_-_146644122 0.988 ENST00000254101.3
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr16_-_68269971 0.986 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr6_+_43737939 0.982 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr18_+_55102917 0.977 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr8_+_87354945 0.954 ENST00000517970.1
WWP1
WW domain containing E3 ubiquitin protein ligase 1
chr1_+_65613217 0.935 ENST00000545314.1
AK4
adenylate kinase 4
chr2_+_231902193 0.907 ENST00000373640.4
C2orf72
chromosome 2 open reading frame 72
chr6_+_160390102 0.885 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr10_-_88854518 0.884 ENST00000277865.4
GLUD1
glutamate dehydrogenase 1
chr1_+_39456895 0.867 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1


akirin 1


chr6_+_15246501 0.855 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr12_-_31479045 0.852 ENST00000539409.1
ENST00000395766.1
FAM60A

family with sequence similarity 60, member A

chr2_-_165697920 0.838 ENST00000342193.4
ENST00000375458.2
COBLL1

cordon-bleu WH2 repeat protein-like 1

chr5_+_167718604 0.817 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chrY_+_15016725 0.813 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr12_-_12419703 0.812 ENST00000543091.1
ENST00000261349.4
LRP6

low density lipoprotein receptor-related protein 6

chr6_+_7107999 0.807 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1


ras responsive element binding protein 1


chr20_+_35201857 0.797 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr11_-_57283159 0.771 ENST00000533263.1
ENST00000278426.3
SLC43A1

solute carrier family 43 (amino acid system L transporter), member 1

chr8_+_61591337 0.754 ENST00000423902.2
CHD7
chromodomain helicase DNA binding protein 7
chr6_+_157802165 0.752 ENST00000414563.2
ENST00000359775.5
ZDHHC14

zinc finger, DHHC-type containing 14

chr17_-_65241281 0.751 ENST00000358691.5
ENST00000580168.1
HELZ

helicase with zinc finger

chr17_-_73975444 0.751 ENST00000293217.5
ENST00000537812.1
ACOX1

acyl-CoA oxidase 1, palmitoyl

chr22_-_37915535 0.749 ENST00000403299.1
CARD10
caspase recruitment domain family, member 10
chr12_-_81331697 0.710 ENST00000552864.1
LIN7A
lin-7 homolog A (C. elegans)
chr14_-_55878538 0.707 ENST00000247178.5
ATG14
autophagy related 14
chr8_+_11561660 0.691 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
GATA4


GATA binding protein 4


chr2_-_97405775 0.686 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L




lectin, mannose-binding 2-like




chr14_+_23775971 0.684 ENST00000250405.5
BCL2L2
BCL2-like 2
chr3_+_44379944 0.684 ENST00000396078.3
ENST00000342649.4
TCAIM

T cell activation inhibitor, mitochondrial

chr19_+_30302805 0.668 ENST00000262643.3
ENST00000575243.1
ENST00000357943.5
CCNE1


cyclin E1


chr19_-_7293942 0.664 ENST00000341500.5
ENST00000302850.5
INSR

insulin receptor

chr3_+_187930719 0.661 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr11_-_34379546 0.649 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr1_-_9970227 0.641 ENST00000377263.1
CTNNBIP1
catenin, beta interacting protein 1
chr2_-_122407097 0.635 ENST00000409078.3
CLASP1
cytoplasmic linker associated protein 1
chr17_-_41174424 0.635 ENST00000355653.3
VAT1
vesicle amine transport 1
chr3_+_171758344 0.632 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr16_+_14726672 0.632 ENST00000261658.2
ENST00000563971.1
BFAR

bifunctional apoptosis regulator

chr18_+_13218769 0.632 ENST00000399848.3
ENST00000361205.4
LDLRAD4

low density lipoprotein receptor class A domain containing 4

chr11_+_86748863 0.627 ENST00000340353.7
TMEM135
transmembrane protein 135
chr2_-_220094294 0.622 ENST00000436856.1
ENST00000428226.1
ENST00000409422.1
ENST00000431715.1
ENST00000457841.1
ENST00000439812.1
ENST00000361242.4
ENST00000396761.2
ATG9A







autophagy related 9A







chr8_+_23430157 0.616 ENST00000399967.3
FP15737
FP15737
chr3_-_53381539 0.616 ENST00000606822.1
ENST00000294241.6
ENST00000607628.1
DCP1A


decapping mRNA 1A


chr2_-_11484710 0.612 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr11_-_129062093 0.598 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr13_-_41240717 0.583 ENST00000379561.5
FOXO1
forkhead box O1
chr16_+_85646763 0.573 ENST00000411612.1
ENST00000253458.7
GSE1

Gse1 coiled-coil protein

chr1_+_16174280 0.573 ENST00000375759.3
SPEN
spen family transcriptional repressor
chr20_-_13765526 0.566 ENST00000202816.1
ESF1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr9_-_111696340 0.561 ENST00000374647.5
IKBKAP
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chrX_-_108976521 0.556 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
ACSL4




acyl-CoA synthetase long-chain family member 4




chr8_-_57123815 0.541 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1


pleiomorphic adenoma gene 1


chr3_+_43328004 0.540 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK



SNF related kinase



chr17_+_28705921 0.538 ENST00000225719.4
CPD
carboxypeptidase D
chr20_+_30865429 0.532 ENST00000375712.3
KIF3B
kinesin family member 3B
chr17_-_40761375 0.521 ENST00000543197.1
ENST00000309428.5
FAM134C

family with sequence similarity 134, member C

chr16_-_88851618 0.515 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chrX_-_50557014 0.510 ENST00000376020.2
SHROOM4
shroom family member 4
chr13_+_97874574 0.510 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2


muscleblind-like splicing regulator 2


chr15_-_61521495 0.509 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr17_-_56595196 0.502 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
MTMR4


myotubularin related protein 4


chr5_-_95297678 0.497 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr10_-_11653753 0.494 ENST00000609104.1
USP6NL
USP6 N-terminal like
chr12_-_27167233 0.491 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
TM7SF3






transmembrane 7 superfamily member 3






chr11_+_101981169 0.488 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1



Yes-associated protein 1



chr17_-_79139817 0.484 ENST00000326724.4
AATK
apoptosis-associated tyrosine kinase
chr6_-_134639180 0.470 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr1_-_231560790 0.464 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr12_-_57030115 0.462 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
BAZ2A


bromodomain adjacent to zinc finger domain, 2A


chr1_-_57045228 0.453 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr4_-_111119804 0.451 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr7_-_44924939 0.450 ENST00000395699.2
PURB
purine-rich element binding protein B
chr2_-_227664474 0.449 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr2_+_173940442 0.445 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK


Mitogen-activated protein kinase kinase kinase MLT


chr7_+_128864848 0.436 ENST00000325006.3
ENST00000446544.2
AHCYL2

adenosylhomocysteinase-like 2

chr7_-_143105941 0.432 ENST00000275815.3
EPHA1
EPH receptor A1
chr8_+_81397876 0.431 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr16_-_48644061 0.431 ENST00000262384.3
N4BP1
NEDD4 binding protein 1
chr1_+_28696111 0.430 ENST00000373839.3
PHACTR4
phosphatase and actin regulator 4
chr12_+_109554386 0.428 ENST00000338432.7
ACACB
acetyl-CoA carboxylase beta
chr14_-_74485960 0.425 ENST00000556242.1
ENST00000334696.6
ENTPD5

ectonucleoside triphosphate diphosphohydrolase 5

chr16_-_30798492 0.422 ENST00000262525.4
ZNF629
zinc finger protein 629
chr3_-_72496035 0.419 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr12_+_19282643 0.414 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
PLEKHA5





pleckstrin homology domain containing, family A member 5





chr16_+_58549378 0.411 ENST00000310682.2
ENST00000394266.4
ENST00000219315.4
SETD6


SET domain containing 6


chr1_-_115212696 0.409 ENST00000393276.3
ENST00000393277.1
DENND2C

DENN/MADD domain containing 2C

chr17_+_40834580 0.404 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr20_+_3776371 0.403 ENST00000245960.5
CDC25B
cell division cycle 25B
chr7_+_4721885 0.401 ENST00000328914.4
FOXK1
forkhead box K1
chr15_+_41851211 0.401 ENST00000263798.3
TYRO3
TYRO3 protein tyrosine kinase
chr19_+_47421933 0.397 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr7_+_99613195 0.393 ENST00000324306.6
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr8_-_82024290 0.388 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr2_+_113239710 0.387 ENST00000233336.6
TTL
tubulin tyrosine ligase
chr3_-_48471454 0.375 ENST00000296440.6
ENST00000448774.2
PLXNB1

plexin B1

chr10_+_104678032 0.371 ENST00000369878.4
ENST00000369875.3
CNNM2

cyclin M2

chr10_+_88516396 0.367 ENST00000372037.3
BMPR1A
bone morphogenetic protein receptor, type IA
chr17_-_48785216 0.365 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr2_-_2334888 0.361 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chr13_+_113622810 0.355 ENST00000397030.1
MCF2L
MCF.2 cell line derived transforming sequence-like
chr17_+_4901199 0.350 ENST00000320785.5
ENST00000574165.1
KIF1C

kinesin family member 1C

chr11_-_72853091 0.349 ENST00000311172.7
ENST00000409314.1
FCHSD2

FCH and double SH3 domains 2

chr7_-_994302 0.345 ENST00000265846.5
ADAP1
ArfGAP with dual PH domains 1
chr11_+_124492749 0.343 ENST00000531667.1
ENST00000441174.3
ENST00000375005.4
TBRG1


transforming growth factor beta regulator 1


chr2_+_203879568 0.341 ENST00000449802.1
NBEAL1
neurobeachin-like 1
chr9_+_35749203 0.338 ENST00000456972.2
ENST00000378078.4
RGP1

RGP1 retrograde golgi transport homolog (S. cerevisiae)

chr5_+_140235469 0.334 ENST00000506939.2
ENST00000307360.5
PCDHA10

protocadherin alpha 10

chr12_+_53399942 0.330 ENST00000262056.9
EIF4B
eukaryotic translation initiation factor 4B
chr5_+_65440032 0.329 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr1_-_114355083 0.329 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chr22_+_21271714 0.327 ENST00000354336.3
CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr6_-_79787902 0.327 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr1_+_52870227 0.325 ENST00000257181.9
PRPF38A
pre-mRNA processing factor 38A
chr5_+_157170703 0.325 ENST00000286307.5
LSM11
LSM11, U7 small nuclear RNA associated
chr2_+_28615669 0.323 ENST00000379619.1
ENST00000264716.4
FOSL2

FOS-like antigen 2

chr10_-_120840309 0.322 ENST00000369144.3
EIF3A
eukaryotic translation initiation factor 3, subunit A
chr22_+_40573921 0.322 ENST00000454349.2
ENST00000335727.9
TNRC6B

trinucleotide repeat containing 6B

chr20_-_1165117 0.320 ENST00000381894.3
TMEM74B
transmembrane protein 74B
chr19_+_19496624 0.314 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATAD2A


GATA zinc finger domain containing 2A


chr11_+_14665263 0.313 ENST00000282096.4
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr11_+_9406169 0.311 ENST00000379719.3
ENST00000527431.1
IPO7

importin 7

chr1_+_82266053 0.311 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2






latrophilin 2






chr6_+_142468361 0.311 ENST00000367630.4
VTA1
vesicle (multivesicular body) trafficking 1
chr19_-_5978090 0.310 ENST00000592621.1
ENST00000034275.8
ENST00000591092.1
ENST00000591333.1
ENST00000590623.1
ENST00000439268.2
ENST00000587159.1
RANBP3






RAN binding protein 3






chr6_-_90529418 0.309 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1


MDN1, midasin homolog (yeast)


chr6_-_154831779 0.306 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr5_+_140261703 0.306 ENST00000409494.1
ENST00000289272.2
PCDHA13

protocadherin alpha 13

chr3_+_53195136 0.302 ENST00000394729.2
ENST00000330452.3
PRKCD

protein kinase C, delta

chr20_-_34287259 0.297 ENST00000397425.1
ENST00000540053.1
ENST00000541387.1
ENST00000374092.4
NFS1



NFS1 cysteine desulfurase



chr7_-_123389104 0.297 ENST00000223023.4
WASL
Wiskott-Aldrich syndrome-like
chr5_+_140254884 0.295 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr16_+_67927147 0.294 ENST00000291041.5
PSKH1
protein serine kinase H1
chr18_+_67956135 0.290 ENST00000397942.3
SOCS6
suppressor of cytokine signaling 6
chr16_+_71929397 0.289 ENST00000537613.1
ENST00000424485.2
ENST00000606369.1
ENST00000329908.8
ENST00000538850.1
ENST00000541918.1
ENST00000534994.1
ENST00000378798.5
ENST00000539186.1
IST1








increased sodium tolerance 1 homolog (yeast)








chr4_+_160188889 0.289 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr15_-_52861394 0.285 ENST00000563277.1
ENST00000566423.1
ARPP19

cAMP-regulated phosphoprotein, 19kDa

chr3_-_48229846 0.284 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A


cell division cycle 25A


chr11_-_74109422 0.283 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chr16_-_47007545 0.282 ENST00000317089.5
DNAJA2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr14_-_105487381 0.280 ENST00000392590.3
ENST00000336219.3
CDCA4

cell division cycle associated 4

chr4_+_128703295 0.280 ENST00000296464.4
ENST00000508549.1
HSPA4L

heat shock 70kDa protein 4-like

chr16_+_10479906 0.280 ENST00000562527.1
ENST00000396560.2
ENST00000396559.1
ENST00000562102.1
ENST00000543967.1
ENST00000569939.1
ENST00000569900.1
ATF7IP2






activating transcription factor 7 interacting protein 2






chr4_-_90229142 0.279 ENST00000609438.1
GPRIN3
GPRIN family member 3
chr10_-_100995540 0.278 ENST00000370546.1
ENST00000404542.1
HPSE2

heparanase 2

chr3_-_66551351 0.277 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr6_+_32121218 0.275 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2


palmitoyl-protein thioesterase 2


chr1_+_180601139 0.275 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr2_+_220042933 0.273 ENST00000430297.2
FAM134A
family with sequence similarity 134, member A
chr16_+_68119440 0.272 ENST00000346183.3
ENST00000329524.4
NFATC3

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

chr10_-_94003003 0.271 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chrX_-_41782249 0.270 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK




calcium/calmodulin-dependent serine protein kinase (MAGUK family)




chr11_+_118307179 0.265 ENST00000534358.1
ENST00000531904.2
ENST00000389506.5
ENST00000354520.4
KMT2A



lysine (K)-specific methyltransferase 2A



chr5_+_130599735 0.265 ENST00000503291.1
ENST00000360515.3
ENST00000505065.1
CDC42SE2


CDC42 small effector 2


chr2_+_73441350 0.265 ENST00000389501.4
SMYD5
SMYD family member 5
chr12_-_28124903 0.259 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr11_+_69455855 0.257 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr4_-_153601136 0.256 ENST00000504064.1
ENST00000304385.3
TMEM154

transmembrane protein 154

chr17_+_57232690 0.256 ENST00000262293.4
PRR11
proline rich 11
chr2_-_73340146 0.254 ENST00000258098.6
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr16_-_11680791 0.252 ENST00000571976.1
ENST00000413364.2
LITAF

lipopolysaccharide-induced TNF factor

chrX_+_128674213 0.251 ENST00000371113.4
ENST00000357121.5
OCRL

oculocerebrorenal syndrome of Lowe

chr3_-_120068143 0.250 ENST00000295628.3
LRRC58
leucine rich repeat containing 58
chr11_+_46639071 0.248 ENST00000580238.1
ENST00000581416.1
ENST00000529655.1
ENST00000533325.1
ENST00000581438.1
ENST00000583249.1
ENST00000530500.1
ENST00000526508.1
ENST00000578626.1
ENST00000577256.1
ENST00000524625.1
ENST00000582547.1
ENST00000359513.4
ENST00000528494.1
ATG13













autophagy related 13













chr13_-_28545276 0.248 ENST00000381020.7
CDX2
caudal type homeobox 2
chr3_+_142720366 0.245 ENST00000493782.1
ENST00000397933.2
ENST00000473835.2
ENST00000493598.2
U2SURP



U2 snRNP-associated SURP domain containing



chr12_+_94542459 0.243 ENST00000258526.4
PLXNC1
plexin C1
chr5_+_74632993 0.243 ENST00000287936.4
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr1_-_19536744 0.242 ENST00000375267.2
ENST00000375217.2
ENST00000375226.2
ENST00000375254.3
UBR4



ubiquitin protein ligase E3 component n-recognin 4



chr22_-_41985865 0.242 ENST00000216259.7
PMM1
phosphomannomutase 1
chr3_-_119813264 0.241 ENST00000264235.8
GSK3B
glycogen synthase kinase 3 beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0060318 definitive erythrocyte differentiation(GO:0060318)
0.5 2.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.4 1.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.4 1.3 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.4 1.2 GO:0042701 progesterone secretion(GO:0042701)
0.4 1.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.3 1.0 GO:0002575 basophil chemotaxis(GO:0002575)
0.3 0.6 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.3 1.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.3 0.8 GO:0035330 regulation of hippo signaling(GO:0035330)
0.3 0.8 GO:2000051 pericardium morphogenesis(GO:0003344) post-embryonic appendage morphogenesis(GO:0035120) trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536) mammary placode formation(GO:0060596) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 1.0 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.2 0.9 GO:0033197 response to vitamin E(GO:0033197)
0.2 0.7 GO:0071372 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 0.7 GO:0060267 transformation of host cell by virus(GO:0019087) positive regulation of respiratory burst(GO:0060267)
0.2 0.6 GO:0070672 response to interleukin-15(GO:0070672)
0.2 0.9 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.2 1.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 1.1 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.2 0.5 GO:0042759 fatty acid elongation, saturated fatty acid(GO:0019367) long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.4 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 0.9 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 1.4 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.5 GO:0070669 response to interleukin-2(GO:0070669)
0.1 0.5 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.9 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 0.6 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.1 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) cytoplasmic translation(GO:0002181) cytoplasmic translational initiation(GO:0002183)
0.1 0.3 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.3 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1 1.4 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.1 0.2 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.1 0.4 GO:0007144 female meiosis I(GO:0007144)
0.1 1.0 GO:0060324 face development(GO:0060324)
0.1 0.2 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.5 GO:0060242 contact inhibition(GO:0060242)
0.1 1.0 GO:0046718 viral entry into host cell(GO:0046718)
0.1 1.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.3 GO:0060649 nipple development(GO:0060618) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659)
0.1 0.2 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515)
0.1 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.2 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.1 1.6 GO:0051180 vitamin transport(GO:0051180)
0.1 0.3 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.2 GO:0043276 anoikis(GO:0043276)
0.1 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.1 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.5 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.5 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.6 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.7 GO:1901224 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.7 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.4 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.8 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0019919 pathogenesis(GO:0009405) peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.5 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.0 1.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 1.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 1.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509) plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0032908 transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908)
0.0 0.2 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.4 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 1.2 GO:0030837 negative regulation of actin filament polymerization(GO:0030837)
0.0 0.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.6 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 1.1 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.7 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 0.1 GO:0061303 iris morphogenesis(GO:0061072) cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.3 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121) regulation of membrane lipid distribution(GO:0097035)
0.0 0.4 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.2 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0 0.7 GO:0097479 synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.0 0.2 GO:0045060 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.3 GO:0034644 cellular response to UV(GO:0034644)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.0 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.4 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.4 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.0 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.7 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.4 GO:0050868 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.0 GO:0010157 response to chlorate(GO:0010157)
0.0 0.3 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 1.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.4 1.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.2 0.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 0.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.2 0.5 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.7 GO:0032449 CBM complex(GO:0032449)
0.1 1.0 GO:0042587 glycogen granule(GO:0042587)
0.1 1.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.2 GO:1990316 pre-autophagosomal structure(GO:0000407) ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.2 GO:0036452 ESCRT III complex(GO:0000815) ESCRT complex(GO:0036452)
0.0 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 2.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 1.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0097651 phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.4 1.9 GO:0003680 AT DNA binding(GO:0003680)
0.4 1.1 GO:0016362 activin receptor activity, type II(GO:0016362)
0.3 1.0 GO:0016297 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) S-acetyltransferase activity(GO:0016418) phosphopantetheine binding(GO:0031177)
0.2 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.2 1.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 1.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.2 1.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 1.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 0.7 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 0.5 GO:0032422 translation repressor activity, nucleic acid binding(GO:0000900) purine-rich negative regulatory element binding(GO:0032422)
0.1 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.1 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.8 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.3 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 1.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.1 0.5 GO:0009922 fatty acid elongase activity(GO:0009922)
0.1 1.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 2.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 1.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 1.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.2 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.9 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.1 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 2.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.3 GO:0019239 deaminase activity(GO:0019239)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 2.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.0 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.8 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0045030 A1 adenosine receptor binding(GO:0031686) UTP-activated nucleotide receptor activity(GO:0045030)
0.0 0.3 GO:0017069 snRNA binding(GO:0017069)
0.0 0.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 2.6 GO:0004386 helicase activity(GO:0004386)
0.0 0.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 3.1 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 1.3 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 2.1 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.5 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.7 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.