Motif ID: AGCAGCG
Z-value: 0.758
Mature miRNA associated with seed AGCAGCG:
| Name | miRBase Accession |
|---|---|
| hsa-miR-503-5p | MIMAT0002874 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.6 | GO:0007028 | cytoplasm organization(GO:0007028) |
| 0.2 | 0.6 | GO:0033197 | response to vitamin E(GO:0033197) |
| 0.1 | 0.6 | GO:0071313 | cellular response to caffeine(GO:0071313) |
| 0.1 | 0.4 | GO:0031133 | regulation of axon diameter(GO:0031133) regulation of cell projection size(GO:0032536) positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) |
| 0.1 | 0.3 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) |
| 0.1 | 1.7 | GO:1904031 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031) |
| 0.1 | 0.3 | GO:0051231 | mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) |
| 0.1 | 0.3 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 0.1 | 0.2 | GO:0008300 | isoprenoid catabolic process(GO:0008300) |
| 0.1 | 0.2 | GO:0071462 | cellular response to water stimulus(GO:0071462) regulation of cortisol biosynthetic process(GO:2000064) |
| 0.1 | 0.2 | GO:2000078 | epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) regulation of type B pancreatic cell development(GO:2000074) positive regulation of type B pancreatic cell development(GO:2000078) |
| 0.1 | 0.2 | GO:0046671 | regulation of nitrogen utilization(GO:0006808) positive regulation of neuron maturation(GO:0014042) nitrogen utilization(GO:0019740) cochlear nucleus development(GO:0021747) negative regulation of cellular pH reduction(GO:0032848) glial cell apoptotic process(GO:0034349) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) positive regulation of cell maturation(GO:1903431) |
| 0.1 | 0.2 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 0.1 | 0.3 | GO:0051570 | regulation of histone H3-K9 methylation(GO:0051570) |
| 0.0 | 0.4 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.0 | 0.1 | GO:0002575 | basophil chemotaxis(GO:0002575) |
| 0.0 | 0.1 | GO:0036037 | CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.0 | 0.2 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.0 | 0.4 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.2 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 0.2 | GO:0006930 | substrate-dependent cell migration, cell extension(GO:0006930) |
| 0.0 | 1.0 | GO:0030851 | granulocyte differentiation(GO:0030851) |
| 0.0 | 0.2 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
| 0.0 | 0.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 3.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.2 | GO:0032801 | receptor catabolic process(GO:0032801) |
| 0.0 | 0.1 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.0 | 0.1 | GO:0048670 | regulation of collateral sprouting(GO:0048670) |
| 0.0 | 0.1 | GO:0060152 | peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152) |
| 0.0 | 0.1 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
| 0.0 | 0.2 | GO:0032876 | regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023) |
| 0.0 | 0.3 | GO:0034644 | cellular response to UV(GO:0034644) |
| 0.0 | 0.2 | GO:0009220 | pyrimidine ribonucleotide biosynthetic process(GO:0009220) |
| 0.0 | 0.1 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
| 0.0 | 0.0 | GO:0001705 | ectoderm formation(GO:0001705) |
| 0.0 | 0.2 | GO:0095500 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.0 | 0.2 | GO:0006906 | vesicle fusion(GO:0006906) |
| 0.0 | 1.0 | GO:0006986 | response to unfolded protein(GO:0006986) |
| 0.0 | 0.1 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.0 | 0.1 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.0 | 0.6 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.1 | 2.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 0.2 | GO:0097651 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651) |
| 0.0 | 0.2 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.0 | 0.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.3 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 0.3 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.0 | 0.2 | GO:0005883 | neurofilament(GO:0005883) |
| 0.0 | 0.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.6 | GO:0005657 | replication fork(GO:0005657) |
| 0.0 | 0.4 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.2 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.0 | 1.1 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.3 | GO:0005871 | kinesin complex(GO:0005871) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 0.2 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.1 | 0.2 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.0 | 0.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.0 | 0.3 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 0.2 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.0 | 0.2 | GO:0043559 | insulin binding(GO:0043559) |
| 0.0 | 0.3 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.0 | 0.2 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.0 | 0.2 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.0 | 0.5 | GO:0016565 | obsolete general transcriptional repressor activity(GO:0016565) |
| 0.0 | 0.2 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
| 0.0 | 0.4 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.0 | 0.2 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.6 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.1 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.0 | 0.3 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.0 | 0.2 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.0 | 0.1 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.0 | 0.1 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.0 | 0.2 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.0 | 0.4 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.1 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 0.3 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 0.3 | GO:0016409 | palmitoyltransferase activity(GO:0016409) |
| 0.0 | 0.4 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 0.4 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 0.4 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.3 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 0.1 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.0 | 0.1 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
| 0.0 | 0.2 | GO:0015377 | cation:chloride symporter activity(GO:0015377) |
| 0.0 | 0.0 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) |
| 0.0 | 1.2 | GO:0016566 | obsolete specific transcriptional repressor activity(GO:0016566) |
| 0.0 | 0.2 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.0 | 0.6 | GO:0050681 | androgen receptor binding(GO:0050681) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 0.5 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
