Motif ID: ALX3
Z-value: 1.154
Transcription factors associated with ALX3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
ALX3 | ENSG00000156150.6 | ALX3 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 0.8 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
0.2 | 0.6 | GO:0002431 | Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
0.2 | 0.5 | GO:0042097 | lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
0.2 | 0.5 | GO:0002752 | cell surface pattern recognition receptor signaling pathway(GO:0002752) |
0.1 | 0.4 | GO:0010107 | potassium ion import(GO:0010107) |
0.1 | 0.5 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
0.1 | 0.8 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
0.1 | 2.2 | GO:0051923 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) sulfation(GO:0051923) |
0.1 | 0.6 | GO:0019388 | galactose catabolic process(GO:0019388) |
0.1 | 2.5 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
0.1 | 0.5 | GO:0006772 | thiamine metabolic process(GO:0006772) |
0.1 | 0.4 | GO:0072205 | collecting duct development(GO:0072044) metanephric collecting duct development(GO:0072205) |
0.1 | 0.4 | GO:0006562 | proline catabolic process(GO:0006562) |
0.1 | 0.3 | GO:0010957 | negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) |
0.1 | 0.2 | GO:1902414 | protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414) |
0.1 | 0.5 | GO:0015074 | DNA integration(GO:0015074) |
0.0 | 0.3 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
0.0 | 0.3 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
0.0 | 0.3 | GO:0044245 | polysaccharide digestion(GO:0044245) |
0.0 | 0.1 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
0.0 | 0.2 | GO:0009313 | oligosaccharide catabolic process(GO:0009313) |
0.0 | 0.3 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
0.0 | 0.2 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
0.0 | 0.2 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383) |
0.0 | 0.1 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.0 | 0.1 | GO:0046520 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
0.0 | 0.3 | GO:0009120 | deoxyribonucleoside metabolic process(GO:0009120) |
0.0 | 0.2 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.0 | 0.2 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
0.0 | 0.1 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.0 | 0.5 | GO:0050892 | intestinal absorption(GO:0050892) |
0.0 | 0.2 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.0 | 0.1 | GO:0042420 | dopamine catabolic process(GO:0042420) |
0.0 | 0.5 | GO:0014046 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
0.0 | 0.1 | GO:0031635 | adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635) opioid receptor signaling pathway(GO:0038003) |
0.0 | 0.1 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
0.0 | 0.1 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
0.0 | 0.5 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
0.0 | 0.2 | GO:0006071 | glycerol metabolic process(GO:0006071) |
0.0 | 0.1 | GO:0050955 | thermoception(GO:0050955) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 0.8 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 0.5 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.1 | 0.9 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.1 | 0.5 | GO:0045179 | apical cortex(GO:0045179) |
0.0 | 0.3 | GO:0033268 | node of Ranvier(GO:0033268) |
0.0 | 0.8 | GO:0042627 | chylomicron(GO:0042627) |
0.0 | 0.3 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
0.0 | 0.5 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
0.0 | 0.1 | GO:0033011 | perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150) |
0.0 | 0.3 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 0.2 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.0 | 0.6 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.0 | 0.5 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 0.3 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 0.5 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 0.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.0 | 0.3 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 2.2 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
0.2 | 0.6 | GO:0003978 | UDP-glucose 4-epimerase activity(GO:0003978) |
0.2 | 0.8 | GO:0042910 | xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910) |
0.2 | 1.1 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.2 | 0.8 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
0.1 | 2.5 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) |
0.1 | 0.5 | GO:0008907 | integrase activity(GO:0008907) |
0.1 | 0.3 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
0.1 | 0.4 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
0.1 | 0.8 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.1 | 0.3 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.1 | 0.5 | GO:0030492 | hemoglobin binding(GO:0030492) |
0.1 | 0.3 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
0.1 | 0.3 | GO:0004083 | bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) |
0.1 | 0.4 | GO:0001846 | opsonin binding(GO:0001846) |
0.1 | 0.3 | GO:0004558 | alpha-1,4-glucosidase activity(GO:0004558) |
0.1 | 0.3 | GO:0080030 | methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032) |
0.0 | 0.4 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
0.0 | 0.3 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
0.0 | 0.1 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
0.0 | 0.2 | GO:0005499 | vitamin D binding(GO:0005499) |
0.0 | 0.2 | GO:0003680 | AT DNA binding(GO:0003680) |
0.0 | 0.2 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.0 | 0.4 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.5 | GO:0030276 | clathrin binding(GO:0030276) |
0.0 | 0.2 | GO:0016004 | phospholipase activator activity(GO:0016004) |
0.0 | 0.2 | GO:0008158 | hedgehog receptor activity(GO:0008158) |
0.0 | 0.2 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.0 | 0.1 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.0 | 0.3 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.0 | 0.2 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.0 | 0.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.0 | 0.1 | GO:0004802 | transketolase activity(GO:0004802) |
0.0 | 0.3 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.0 | 0.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.3 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
0.0 | 0.5 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) acetylcholine receptor activity(GO:0015464) |
0.0 | 0.1 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.0 | 0.2 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) |
0.0 | 0.2 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
0.0 | 0.2 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.0 | 0.1 | GO:0004988 | obsolete mu-opioid receptor activity(GO:0004988) |
0.0 | 0.2 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.0 | 0.2 | GO:0008527 | taste receptor activity(GO:0008527) |
0.0 | 0.5 | GO:0015026 | coreceptor activity(GO:0015026) |
0.0 | 0.4 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.3 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.0 | 0.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.3 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.7 | GO:0042562 | hormone binding(GO:0042562) |
0.0 | 0.2 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.3 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |