Motif ID: ARID5A
Z-value: 1.102
Transcription factors associated with ARID5A:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| ARID5A | ENSG00000196843.11 | ARID5A |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.1 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.2 | 6.2 | GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.2 | 1.0 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 0.1 | 0.4 | GO:0019441 | tryptophan catabolic process to kynurenine(GO:0019441) |
| 0.1 | 0.4 | GO:1901798 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798) |
| 0.1 | 0.3 | GO:0006382 | adenosine to inosine editing(GO:0006382) |
| 0.1 | 0.4 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
| 0.1 | 1.4 | GO:0050872 | white fat cell differentiation(GO:0050872) |
| 0.1 | 0.5 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 0.1 | 0.3 | GO:0042231 | interleukin-13 biosynthetic process(GO:0042231) |
| 0.1 | 0.4 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.1 | 0.5 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.1 | 0.6 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
| 0.1 | 1.0 | GO:0050718 | positive regulation of interleukin-1 beta secretion(GO:0050718) |
| 0.1 | 0.1 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.1 | 0.2 | GO:0071418 | uroporphyrinogen III biosynthetic process(GO:0006780) cellular response to amine stimulus(GO:0071418) |
| 0.1 | 0.2 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.1 | 0.7 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.1 | 0.4 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.1 | 0.4 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 1.1 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.0 | 0.2 | GO:0008298 | intracellular mRNA localization(GO:0008298) minus-end-directed organelle transport along microtubule(GO:0072385) microtubule anchoring at microtubule organizing center(GO:0072393) |
| 0.0 | 0.2 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.0 | 0.2 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 0.0 | 0.3 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.0 | 0.3 | GO:0032472 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071) |
| 0.0 | 0.5 | GO:0019987 | obsolete negative regulation of anti-apoptosis(GO:0019987) |
| 0.0 | 0.2 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
| 0.0 | 0.2 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.0 | 0.9 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.0 | 0.2 | GO:0060084 | synaptic transmission involved in micturition(GO:0060084) |
| 0.0 | 0.6 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.0 | 0.1 | GO:0060152 | peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152) |
| 0.0 | 0.3 | GO:0001946 | lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303) |
| 0.0 | 0.2 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.0 | 1.2 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124) |
| 0.0 | 0.2 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.0 | 0.3 | GO:0009629 | response to gravity(GO:0009629) |
| 0.0 | 0.1 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.0 | 0.2 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.0 | 0.2 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.0 | 0.1 | GO:0006848 | pyruvate transport(GO:0006848) |
| 0.0 | 1.0 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 3.0 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 0.2 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.0 | GO:0070857 | regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251) |
| 0.0 | 0.4 | GO:0042403 | thyroid hormone metabolic process(GO:0042403) |
| 0.0 | 0.2 | GO:0045329 | amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329) |
| 0.0 | 0.1 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.0 | 0.2 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.0 | 0.2 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 0.0 | 0.1 | GO:0046668 | regulation of retinal cell programmed cell death(GO:0046668) |
| 0.0 | 0.1 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.0 | 1.3 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 0.0 | 0.5 | GO:0048661 | positive regulation of smooth muscle cell proliferation(GO:0048661) |
| 0.0 | 1.8 | GO:0007162 | negative regulation of cell adhesion(GO:0007162) |
| 0.0 | 0.2 | GO:0032876 | regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023) |
| 0.0 | 0.1 | GO:0055015 | ventricular cardiac muscle cell development(GO:0055015) |
| 0.0 | 0.0 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.0 | 0.0 | GO:0000019 | regulation of mitotic recombination(GO:0000019) |
| 0.0 | 0.2 | GO:0060638 | mesenchymal-epithelial cell signaling(GO:0060638) |
| 0.0 | 1.2 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.0 | 0.5 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.0 | 0.0 | GO:0070995 | NADPH oxidation(GO:0070995) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.1 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.3 | 6.2 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 0.4 | GO:0001741 | XY body(GO:0001741) |
| 0.1 | 0.2 | GO:0033655 | host(GO:0018995) host cell cytoplasm(GO:0030430) host cell part(GO:0033643) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
| 0.1 | 1.2 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.1 | 0.3 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.1 | 1.0 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.4 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.0 | 0.6 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 0.2 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 0.0 | 0.2 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 0.2 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.0 | 0.2 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 0.3 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 0.8 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.0 | 0.2 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.0 | 0.1 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 1.4 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.1 | GO:0044298 | neuronal cell body membrane(GO:0032809) synaptic cleft(GO:0043083) cell body membrane(GO:0044298) |
| 0.0 | 0.1 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.0 | 0.2 | GO:0032300 | mismatch repair complex(GO:0032300) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.2 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
| 0.3 | 1.0 | GO:0032089 | NACHT domain binding(GO:0032089) |
| 0.3 | 3.9 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.2 | 2.1 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.2 | 2.6 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
| 0.2 | 1.0 | GO:0034597 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
| 0.2 | 1.0 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.2 | 0.5 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.1 | 0.4 | GO:0030377 | urokinase plasminogen activator receptor activity(GO:0030377) |
| 0.1 | 0.6 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.1 | 0.5 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
| 0.1 | 0.3 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 0.1 | 0.4 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.1 | 0.2 | GO:0004476 | mannose-6-phosphate isomerase activity(GO:0004476) |
| 0.1 | 0.5 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 0.1 | 0.2 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 0.1 | 0.9 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.1 | 0.4 | GO:0031404 | chloride ion binding(GO:0031404) |
| 0.0 | 0.1 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.0 | 0.3 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
| 0.0 | 0.2 | GO:0070492 | oligosaccharide binding(GO:0070492) |
| 0.0 | 0.2 | GO:0052590 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.0 | 0.3 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 0.2 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.0 | 0.3 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.0 | 1.2 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.4 | GO:0032407 | MutSalpha complex binding(GO:0032407) |
| 0.0 | 0.4 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.0 | 0.2 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.4 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 0.0 | 0.1 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.0 | 0.4 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.0 | 0.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.1 | GO:0050833 | pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833) |
| 0.0 | 0.8 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 1.5 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.1 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.2 | GO:0043176 | amine binding(GO:0043176) |
| 0.0 | 0.1 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.0 | 0.1 | GO:0016615 | malate dehydrogenase activity(GO:0016615) |
| 0.0 | 0.2 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.0 | 0.5 | GO:0008373 | sialyltransferase activity(GO:0008373) |
| 0.0 | 0.5 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 1.4 | GO:0051287 | NAD binding(GO:0051287) |
| 0.0 | 0.2 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.0 | 0.6 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.2 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.0 | 0.2 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.0 | 0.2 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.2 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.2 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.1 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.0 | 0.2 | GO:0016986 | obsolete transcription initiation factor activity(GO:0016986) |
| 0.0 | 0.1 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.0 | 0.3 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.0 | 1.2 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.2 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.0 | 0.1 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.0 | 0.2 | GO:0042166 | acetylcholine binding(GO:0042166) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
