Motif ID: AR_NR3C2

Z-value: 1.808

Transcription factors associated with AR_NR3C2:

Gene SymbolEntrez IDGene Name
AR ENSG00000169083.11 AR
NR3C2 ENSG00000151623.10 NR3C2






Network of associatons between targets according to the STRING database.



First level regulatory network of AR_NR3C2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_56659687 8.850 ENST00000568293.1
ENST00000330439.6
MT1E

metallothionein 1E

chr16_+_56642041 7.522 ENST00000245185.5
MT2A
metallothionein 2A
chr16_+_56642489 6.604 ENST00000561491.1
MT2A
metallothionein 2A
chr16_+_56716336 6.210 ENST00000394485.4
ENST00000562939.1
MT1X

metallothionein 1X

chr8_-_49834299 5.208 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr8_-_49833978 4.828 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr7_-_94285402 3.037 ENST00000428696.2
ENST00000445866.2
SGCE

sarcoglycan, epsilon

chr7_-_94285511 3.033 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr2_+_238395879 2.841 ENST00000445024.2
ENST00000338530.4
ENST00000409373.1
MLPH


melanophilin


chr2_+_238395803 2.744 ENST00000264605.3
MLPH
melanophilin
chr16_+_56672571 2.717 ENST00000290705.8
MT1A
metallothionein 1A
chr16_+_56666563 2.609 ENST00000570233.1
MT1M
metallothionein 1M
chr4_+_75310851 2.497 ENST00000395748.3
ENST00000264487.2
AREG

amphiregulin

chr11_+_18287721 2.484 ENST00000356524.4
SAA1
serum amyloid A1
chr11_+_18287801 2.385 ENST00000532858.1
ENST00000405158.2
SAA1

serum amyloid A1

chr4_+_75311019 2.376 ENST00000502307.1
AREG
amphiregulin
chr4_+_75480629 2.353 ENST00000380846.3
AREGB
amphiregulin B
chr7_-_94285472 1.559 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE


sarcoglycan, epsilon


chr5_+_140186647 1.241 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4


protocadherin alpha 4


chr8_+_9046503 1.079 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chrX_+_17755563 0.994 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1



sex comb on midleg-like 1 (Drosophila)



chr18_+_56530136 0.890 ENST00000591083.1
ZNF532
zinc finger protein 532
chr18_+_7754957 0.830 ENST00000400053.4
PTPRM
protein tyrosine phosphatase, receptor type, M
chr6_-_111927062 0.735 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chrX_+_2609317 0.725 ENST00000381187.3
ENST00000381184.1
CD99

CD99 molecule

chrX_+_2609356 0.699 ENST00000381180.3
ENST00000449611.1
CD99

CD99 molecule

chrX_+_2609207 0.658 ENST00000381192.3
CD99
CD99 molecule
chr12_+_53443680 0.649 ENST00000314250.6
ENST00000451358.1
TENC1

tensin like C1 domain containing phosphatase (tensin 2)

chr7_+_94285637 0.623 ENST00000482108.1
ENST00000488574.1
PEG10

paternally expressed 10

chr16_+_67207838 0.608 ENST00000566871.1
ENST00000268605.7
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr1_-_145715565 0.546 ENST00000369288.2
ENST00000369290.1
ENST00000401557.3
CD160


CD160 molecule


chr12_+_125549925 0.538 ENST00000316519.6
AACS
acetoacetyl-CoA synthetase
chr16_-_66584059 0.533 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2





thymidine kinase 2, mitochondrial





chr8_-_62602327 0.518 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH









aspartate beta-hydroxylase









chr14_-_107211459 0.512 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr16_+_67207872 0.505 ENST00000563258.1
ENST00000568146.1
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr22_+_23046750 0.505 ENST00000390307.2
IGLV3-22
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr15_+_31658349 0.446 ENST00000558844.1
KLF13
Kruppel-like factor 13
chr12_+_125549973 0.435 ENST00000536752.1
ENST00000261686.6
AACS

acetoacetyl-CoA synthetase

chr12_+_53443963 0.428 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1


tensin like C1 domain containing phosphatase (tensin 2)


chr8_+_91013577 0.420 ENST00000220764.2
DECR1
2,4-dienoyl CoA reductase 1, mitochondrial
chr19_+_35630344 0.391 ENST00000455515.2
FXYD1
FXYD domain containing ion transport regulator 1
chr1_-_27693349 0.358 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
MAP3K6


mitogen-activated protein kinase kinase kinase 6


chr17_+_41323204 0.334 ENST00000542611.1
ENST00000590996.1
ENST00000389312.4
ENST00000589872.1
NBR1



neighbor of BRCA1 gene 1



chr12_+_66582919 0.327 ENST00000545837.1
ENST00000457197.2
IRAK3

interleukin-1 receptor-associated kinase 3

chr11_-_506739 0.325 ENST00000529306.1
ENST00000438658.2
ENST00000527485.1
ENST00000397615.2
ENST00000397614.1
RNH1




ribonuclease/angiogenin inhibitor 1




chr17_-_19290117 0.302 ENST00000497081.2
MFAP4
microfibrillar-associated protein 4
chr4_-_8442438 0.281 ENST00000356406.5
ENST00000413009.2
ACOX3

acyl-CoA oxidase 3, pristanoyl

chr17_+_38333263 0.272 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1




Rap guanine nucleotide exchange factor (GEF)-like 1




chr2_+_27435179 0.271 ENST00000606999.1
ENST00000405489.3
ATRAID

all-trans retinoic acid-induced differentiation factor

chr19_+_57874835 0.249 ENST00000282282.3
ENST00000543226.1
ENST00000596755.1
ENST00000597658.1
ZNF547
TRAPPC2P1

AC003002.4
zinc finger protein 547
trafficking protein particle complex 2 pseudogene 1

Uncharacterized protein
chr8_-_21669826 0.225 ENST00000517328.1
GFRA2
GDNF family receptor alpha 2
chr19_-_8408139 0.224 ENST00000330915.3
ENST00000593649.1
ENST00000595639.1
KANK3


KN motif and ankyrin repeat domains 3


chr17_-_19290483 0.198 ENST00000395592.2
ENST00000299610.4
MFAP4

microfibrillar-associated protein 4

chr12_-_10251603 0.196 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr8_+_91013676 0.195 ENST00000519410.1
ENST00000522161.1
ENST00000517761.1
ENST00000520227.1
DECR1



2,4-dienoyl CoA reductase 1, mitochondrial



chr1_+_22979676 0.161 ENST00000432749.2
ENST00000314933.6
C1QB

complement component 1, q subcomponent, B chain

chr1_+_22979474 0.159 ENST00000509305.1
C1QB
complement component 1, q subcomponent, B chain
chr19_+_35630926 0.146 ENST00000588081.1
ENST00000589121.1
FXYD1

FXYD domain containing ion transport regulator 1

chr3_-_58563094 0.134 ENST00000464064.1
FAM107A
family with sequence similarity 107, member A
chr19_+_35630628 0.134 ENST00000588715.1
ENST00000588607.1
FXYD1

FXYD domain containing ion transport regulator 1

chr19_+_58570605 0.119 ENST00000359978.6
ENST00000401053.4
ENST00000439855.2
ENST00000313434.5
ENST00000511556.1
ENST00000506786.1
ZNF135





zinc finger protein 135





chr16_-_67978016 0.095 ENST00000264005.5
LCAT
lecithin-cholesterol acyltransferase
chr17_-_16472483 0.090 ENST00000395824.1
ENST00000448349.2
ENST00000395825.3
ZNF287


zinc finger protein 287


chr15_+_42694573 0.077 ENST00000397200.4
ENST00000569827.1
CAPN3

calpain 3, (p94)

chr1_+_76262552 0.076 ENST00000263187.3
MSH4
mutS homolog 4
chr22_+_19939026 0.069 ENST00000406520.3
COMT
catechol-O-methyltransferase
chr19_-_14117074 0.062 ENST00000588885.1
ENST00000254325.4
RFX1

regulatory factor X, 1 (influences HLA class II expression)

chr12_-_56615693 0.060 ENST00000394013.2
ENST00000345093.4
ENST00000551711.1
ENST00000552656.1
RNF41



ring finger protein 41



chr11_+_114270752 0.054 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr5_-_179499086 0.053 ENST00000261947.4
RNF130
ring finger protein 130
chr2_+_242577027 0.052 ENST00000402096.1
ENST00000404914.3
ATG4B

autophagy related 4B, cysteine peptidase

chr12_-_11002063 0.045 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4


proline rich 4 (lacrimal)


chr5_-_179499108 0.042 ENST00000521389.1
RNF130
ring finger protein 130
chr19_+_54704610 0.016 ENST00000302907.4
RPS9
ribosomal protein S9
chr4_-_69215467 0.014 ENST00000579690.1
YTHDC1
YTH domain containing 1
chr2_+_102953608 0.011 ENST00000311734.2
ENST00000409584.1
IL1RL1

interleukin 1 receptor-like 1

chr3_+_13521665 0.004 ENST00000295757.3
ENST00000402259.1
ENST00000402271.1
ENST00000446613.2
ENST00000404548.1
ENST00000404040.1
HDAC11





histone deacetylase 11





chr5_-_179498703 0.002 ENST00000522208.2
RNF130
ring finger protein 130

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.7 10.0 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.3 5.6 GO:0032400 melanosome localization(GO:0032400)
0.2 1.0 GO:0034201 response to oleic acid(GO:0034201)
0.1 0.8 GO:0010842 retina layer formation(GO:0010842)
0.1 0.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 4.9 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 0.5 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 7.2 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 5.4 GO:0010038 response to metal ion(GO:0010038)
0.0 0.1 GO:0050668 positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of cellular amino acid metabolic process(GO:0045764) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.5 GO:0001527 microfibril(GO:0001527)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 5.6 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.3 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.6 GO:0046870 cadmium ion binding(GO:0046870)
0.6 5.6 GO:0031489 myosin V binding(GO:0031489)
0.2 0.6 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.2 0.5 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 0.5 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.3 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 1.0 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.5 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 4.5 GO:0005125 cytokine activity(GO:0005125)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)