Motif ID: AUGGCAC

Z-value: 0.564


Mature miRNA associated with seed AUGGCAC:

NamemiRBase Accession
hsa-miR-183-5p.1 MIMAT0000261



Activity profile for motif AUGGCAC.

activity profile for motif AUGGCAC


Sorted Z-values histogram for motif AUGGCAC

Sorted Z-values for motif AUGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AUGGCAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_88928777 0.692 ENST00000237596.2
PKD2
polycystic kidney disease 2 (autosomal dominant)
chrX_+_12993202 0.626 ENST00000451311.2
ENST00000380636.1
TMSB4X

thymosin beta 4, X-linked

chr10_+_11206925 0.556 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2


CUGBP, Elav-like family member 2


chr7_+_69064300 0.492 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr1_-_68299130 0.485 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr2_-_227664474 0.478 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr1_+_78470530 0.456 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr5_-_81046922 0.456 ENST00000514493.1
ENST00000320672.4
SSBP2

single-stranded DNA binding protein 2

chr9_+_132934835 0.447 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr9_-_16870704 0.444 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2



basonuclin 2



chr1_-_221915418 0.416 ENST00000323825.3
ENST00000366899.3
DUSP10

dual specificity phosphatase 10

chrX_-_11445856 0.392 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr7_-_16685422 0.364 ENST00000306999.2
ANKMY2
ankyrin repeat and MYND domain containing 2
chr11_+_12695944 0.359 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr8_-_18871159 0.346 ENST00000327040.8
ENST00000440756.2
PSD3

pleckstrin and Sec7 domain containing 3

chr13_-_23949671 0.346 ENST00000402364.1
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr18_-_53255766 0.334 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4




transcription factor 4




chr1_-_94374946 0.325 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chr10_+_31608054 0.325 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1





zinc finger E-box binding homeobox 1





chr8_-_23712312 0.321 ENST00000290271.2
STC1
stanniocalcin 1
chr12_+_72666407 0.285 ENST00000261180.4
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr8_+_106330920 0.284 ENST00000407775.2
ZFPM2
zinc finger protein, FOG family member 2
chr8_+_48920960 0.267 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
UBE2V2



ubiquitin-conjugating enzyme E2 variant 2



chr5_+_61602055 0.264 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr1_+_203595903 0.255 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4


ATPase, Ca++ transporting, plasma membrane 4


chr15_-_83316254 0.250 ENST00000567678.1
ENST00000450751.2
CPEB1

cytoplasmic polyadenylation element binding protein 1

chr2_-_222436988 0.238 ENST00000409854.1
ENST00000281821.2
ENST00000392071.4
ENST00000443796.1
EPHA4



EPH receptor A4



chr5_+_65222299 0.237 ENST00000284037.5
ERBB2IP
erbb2 interacting protein
chr9_-_79520989 0.236 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2


prune homolog 2 (Drosophila)


chr12_-_76953284 0.236 ENST00000547544.1
ENST00000393249.2
OSBPL8

oxysterol binding protein-like 8

chr5_-_142783175 0.231 ENST00000231509.3
ENST00000394464.2
NR3C1

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

chr2_-_161350305 0.209 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr12_+_4382917 0.205 ENST00000261254.3
CCND2
cyclin D2
chr2_+_201676256 0.194 ENST00000452206.1
ENST00000410110.2
ENST00000409600.1
BZW1


basic leucine zipper and W2 domains 1


chr4_+_79697495 0.177 ENST00000502871.1
ENST00000335016.5
BMP2K

BMP2 inducible kinase

chr10_-_52383644 0.174 ENST00000361781.2
SGMS1
sphingomyelin synthase 1
chr4_-_129208940 0.174 ENST00000296425.5
PGRMC2
progesterone receptor membrane component 2
chr5_+_118407053 0.170 ENST00000311085.8
ENST00000539542.1
DMXL1

Dmx-like 1

chr12_+_79258547 0.169 ENST00000457153.2
SYT1
synaptotagmin I
chr11_+_125034586 0.169 ENST00000298282.9
PKNOX2
PBX/knotted 1 homeobox 2
chr13_+_76123883 0.168 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr8_-_30670384 0.167 ENST00000221138.4
ENST00000518243.1
PPP2CB

protein phosphatase 2, catalytic subunit, beta isozyme

chr4_+_154125565 0.164 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr15_+_57210818 0.163 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12




transcription factor 12




chr1_-_225840747 0.163 ENST00000366843.2
ENST00000366844.3
ENAH

enabled homolog (Drosophila)

chrY_+_15815447 0.160 ENST00000284856.3
TMSB4Y
thymosin beta 4, Y-linked
chr3_+_152017181 0.159 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1



muscleblind-like splicing regulator 1



chr7_+_155089486 0.151 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
INSIG1



insulin induced gene 1



chr1_+_227058264 0.138 ENST00000366783.3
ENST00000340188.4
ENST00000495488.1
ENST00000422240.2
PSEN2



presenilin 2 (Alzheimer disease 4)



chr1_+_215256467 0.135 ENST00000391894.2
ENST00000444842.2
KCNK2

potassium channel, subfamily K, member 2

chr6_-_159239257 0.132 ENST00000337147.7
ENST00000392177.4
EZR

ezrin

chr3_-_160283348 0.128 ENST00000334256.4
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr10_-_33246722 0.126 ENST00000437302.1
ENST00000396033.2
ITGB1

integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

chr8_+_26149007 0.124 ENST00000380737.3
ENST00000524169.1
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chr10_+_126490354 0.122 ENST00000298492.5
FAM175B
family with sequence similarity 175, member B
chr3_-_149688896 0.121 ENST00000239940.7
PFN2
profilin 2
chr2_-_183903133 0.120 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr5_-_133561752 0.117 ENST00000481195.1
ENST00000519718.1
PPP2CA
CTD-2410N18.5
protein phosphatase 2, catalytic subunit, alpha isozyme
S-phase kinase-associated protein 1
chr10_+_22605304 0.117 ENST00000456711.1
ENST00000444869.1
ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
COMMD3

COMMD3-BMI1


COMM domain containing 3

COMMD3-BMI1 readthrough


chr1_+_25071848 0.117 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr3_+_130569429 0.114 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr10_-_104262426 0.112 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr5_+_151151471 0.112 ENST00000394123.3
ENST00000543466.1
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr14_-_50999307 0.109 ENST00000013125.4
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr15_+_63334831 0.107 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
TPM1








tropomyosin 1 (alpha)








chr11_+_18344106 0.103 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1


general transcription factor IIH, polypeptide 1, 62kDa


chr19_-_14316980 0.101 ENST00000361434.3
ENST00000340736.6
LPHN1

latrophilin 1

chr10_-_33623564 0.101 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chr9_-_80646374 0.100 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr5_-_127873659 0.100 ENST00000262464.4
FBN2
fibrillin 2
chr7_+_35840542 0.096 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7



septin 7



chr9_+_82186872 0.090 ENST00000376544.3
ENST00000376520.4
TLE4

transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)

chr4_-_187644930 0.089 ENST00000441802.2
FAT1
FAT atypical cadherin 1
chr2_+_148602058 0.087 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
ACVR2A


activin A receptor, type IIA


chr8_-_93115445 0.087 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_157189180 0.086 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2




nuclear receptor subfamily 4, group A, member 2




chr5_+_133861790 0.083 ENST00000395003.1
PHF15
jade family PHD finger 2
chr20_-_14318248 0.082 ENST00000378053.3
ENST00000341420.4
FLRT3

fibronectin leucine rich transmembrane protein 3

chr4_-_2264015 0.081 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr9_-_114246635 0.079 ENST00000338205.5
KIAA0368
KIAA0368
chr1_-_240775447 0.079 ENST00000318160.4
GREM2
gremlin 2, DAN family BMP antagonist
chr1_-_160254913 0.076 ENST00000608310.1
ENST00000440949.3
ENST00000368072.5
ENST00000556710.1
DCAF8
PEX19

DCAF8
DDB1 and CUL4 associated factor 8
peroxisomal biogenesis factor 19

DDB1- and CUL4-associated factor 8
chr1_+_193091080 0.075 ENST00000367435.3
CDC73
cell division cycle 73
chr10_+_64893039 0.073 ENST00000277746.6
ENST00000435510.2
NRBF2

nuclear receptor binding factor 2

chr18_+_32073253 0.072 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA


dystrobrevin, alpha


chr14_-_82000140 0.072 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L


sel-1 suppressor of lin-12-like (C. elegans)


chr17_-_1359443 0.071 ENST00000574295.1
ENST00000398970.5
ENST00000300574.2
CRK


v-crk avian sarcoma virus CT10 oncogene homolog


chr1_-_1822495 0.069 ENST00000378609.4
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr12_-_42632016 0.069 ENST00000442791.3
ENST00000327791.4
ENST00000534854.2
ENST00000380788.3
ENST00000380790.4
YAF2




YY1 associated factor 2




chr17_+_64298944 0.068 ENST00000413366.3
PRKCA
protein kinase C, alpha
chr1_+_181452678 0.067 ENST00000367570.1
ENST00000526775.1
ENST00000357570.5
ENST00000358338.5
ENST00000367567.4
CACNA1E




calcium channel, voltage-dependent, R type, alpha 1E subunit




chr18_+_67956135 0.067 ENST00000397942.3
SOCS6
suppressor of cytokine signaling 6
chr14_+_105331596 0.063 ENST00000556508.1
ENST00000414716.3
ENST00000453495.1
ENST00000418279.1
CEP170B



centrosomal protein 170B



chr8_+_41348072 0.063 ENST00000405786.2
GOLGA7
golgin A7
chr10_+_92980517 0.061 ENST00000336126.5
PCGF5
polycomb group ring finger 5
chr15_+_77223960 0.061 ENST00000394885.3
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr10_+_22610124 0.060 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr15_+_64388166 0.058 ENST00000353874.4
ENST00000261889.5
ENST00000559844.1
ENST00000561026.1
ENST00000558040.1
SNX1




sorting nexin 1




chr8_+_32405728 0.056 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
NRG1




neuregulin 1




chr4_+_148538517 0.056 ENST00000296582.3
ENST00000508208.1
TMEM184C

transmembrane protein 184C

chr1_-_154155595 0.054 ENST00000328159.4
ENST00000368531.2
ENST00000323144.7
ENST00000368533.3
ENST00000341372.3
TPM3




tropomyosin 3




chr8_+_42010464 0.054 ENST00000518421.1
ENST00000174653.3
ENST00000396926.3
ENST00000521280.1
ENST00000522288.1
AP3M2




adaptor-related protein complex 3, mu 2 subunit




chr8_+_64081118 0.051 ENST00000539294.1
YTHDF3
YTH domain family, member 3
chr3_+_169940153 0.051 ENST00000295797.4
PRKCI
protein kinase C, iota
chr17_-_74733404 0.049 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
SRSF2




serine/arginine-rich splicing factor 2




chr3_-_116164306 0.049 ENST00000490035.2
LSAMP
limbic system-associated membrane protein
chr14_+_79745746 0.048 ENST00000281127.7
NRXN3
neurexin 3
chr11_+_45907177 0.047 ENST00000241014.2
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr9_-_127952032 0.044 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
PPP6C


protein phosphatase 6, catalytic subunit


chr11_+_125439298 0.044 ENST00000278903.6
ENST00000343678.4
ENST00000524723.1
ENST00000527842.2
EI24



etoposide induced 2.4



chr3_+_152552685 0.041 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr5_-_77844974 0.040 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr12_+_19282643 0.040 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
PLEKHA5





pleckstrin homology domain containing, family A member 5





chr10_+_102821551 0.040 ENST00000370200.5
KAZALD1
Kazal-type serine peptidase inhibitor domain 1
chr12_+_67663056 0.039 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr20_-_39928705 0.038 ENST00000436099.2
ENST00000309060.3
ENST00000373261.1
ENST00000436440.2
ENST00000540170.1
ENST00000557816.1
ENST00000560361.1
ZHX3






zinc fingers and homeoboxes 3






chr2_+_231577532 0.036 ENST00000258418.5
CAB39
calcium binding protein 39
chr10_+_112631547 0.035 ENST00000280154.7
ENST00000393104.2
PDCD4

programmed cell death 4 (neoplastic transformation inhibitor)

chr6_-_52926539 0.035 ENST00000350082.5
ENST00000356971.3
ICK

intestinal cell (MAK-like) kinase

chr6_-_91006461 0.034 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BACH2



BTB and CNC homology 1, basic leucine zipper transcription factor 2



chr5_-_64064508 0.034 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr12_-_92539614 0.033 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr2_+_192542850 0.033 ENST00000410026.2
NABP1
nucleic acid binding protein 1
chrX_+_136648297 0.032 ENST00000287538.5
ZIC3
Zic family member 3
chr12_-_16761007 0.031 ENST00000354662.1
ENST00000441439.2
LMO3

LIM domain only 3 (rhombotin-like 2)

chr9_-_3525968 0.030 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr3_-_33481835 0.026 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr16_-_75498553 0.026 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
TMEM170A



RP11-77K12.1
transmembrane protein 170A



Uncharacterized protein
chr14_+_33408449 0.025 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
NPAS3




neuronal PAS domain protein 3




chr18_+_48086440 0.025 ENST00000400384.2
ENST00000540640.1
ENST00000592595.1
MAPK4


mitogen-activated protein kinase 4


chr20_+_1875110 0.025 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr5_+_153418466 0.024 ENST00000522782.1
ENST00000439768.2
ENST00000436816.1
ENST00000322602.5
ENST00000522177.1
ENST00000520899.1
MFAP3





microfibrillar-associated protein 3





chr11_-_47198380 0.020 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ARFGAP2








ADP-ribosylation factor GTPase activating protein 2








chr1_-_93257951 0.020 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
EVI5


ecotropic viral integration site 5


chr7_-_17980091 0.020 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
SNX13


sorting nexin 13


chr9_+_33025209 0.016 ENST00000330899.4
ENST00000544625.1
DNAJA1

DnaJ (Hsp40) homolog, subfamily A, member 1

chr17_-_36956155 0.015 ENST00000269554.3
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr14_+_55518349 0.015 ENST00000395468.4
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr3_+_14444063 0.015 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6


solute carrier family 6 (neurotransmitter transporter), member 6


chr19_+_11466062 0.014 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410


Lipid phosphate phosphatase-related protein type 2


chr17_+_30813576 0.012 ENST00000313401.3
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr5_-_59189545 0.012 ENST00000340635.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr9_-_135819987 0.010 ENST00000298552.3
ENST00000403810.1
TSC1

tuberous sclerosis 1

chrX_-_15353629 0.010 ENST00000333590.4
ENST00000428964.1
ENST00000542278.1
PIGA


phosphatidylinositol glycan anchor biosynthesis, class A


chr14_+_55034599 0.010 ENST00000392067.3
ENST00000357634.3
SAMD4A

sterile alpha motif domain containing 4A

chr2_-_166060571 0.009 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr1_+_70671363 0.008 ENST00000370951.1
ENST00000370950.3
ENST00000405432.1
ENST00000454435.2
SRSF11



serine/arginine-rich splicing factor 11



chr5_-_139726181 0.008 ENST00000507104.1
ENST00000230990.6
HBEGF

heparin-binding EGF-like growth factor

chr18_+_29671812 0.007 ENST00000261593.3
ENST00000578914.1
RNF138

ring finger protein 138, E3 ubiquitin protein ligase

chr7_+_20370746 0.006 ENST00000222573.4
ITGB8
integrin, beta 8
chr6_-_94129244 0.006 ENST00000369303.4
ENST00000369297.1
EPHA7

EPH receptor A7

chr3_-_48885228 0.006 ENST00000454963.1
ENST00000296446.8
ENST00000419216.1
ENST00000265563.8
PRKAR2A



protein kinase, cAMP-dependent, regulatory, type II, alpha



chr6_+_163835669 0.006 ENST00000453779.2
ENST00000275262.7
ENST00000392127.2
ENST00000361752.3
QKI



QKI, KH domain containing, RNA binding



chr8_+_26240414 0.006 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr11_-_62572901 0.005 ENST00000439713.2
ENST00000531131.1
ENST00000530875.1
ENST00000531709.2
ENST00000294172.2
NXF1




nuclear RNA export factor 1




chrX_-_131352152 0.005 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr15_-_64673630 0.004 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101


KIAA0101


chr1_-_24306798 0.004 ENST00000374452.5
ENST00000492112.2
ENST00000343255.5
ENST00000344989.6
SRSF10



serine/arginine-rich splicing factor 10



chr17_+_20059302 0.004 ENST00000395530.2
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr1_+_27719148 0.003 ENST00000374024.3
GPR3
G protein-coupled receptor 3
chr19_-_47975417 0.002 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr8_+_98656336 0.002 ENST00000336273.3
MTDH
metadherin
chr2_+_173600671 0.001 ENST00000409036.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr5_+_68462837 0.000 ENST00000256442.5
CCNB1
cyclin B1
chr12_+_69864129 0.000 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2









fibroblast growth factor receptor substrate 2










Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:2001258 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) negative regulation of calcium ion transmembrane transporter activity(GO:1901020) negative regulation of cation channel activity(GO:2001258)
0.2 0.5 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 0.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.3 GO:0051409 response to nitrosative stress(GO:0051409)
0.1 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.4 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.2 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.4 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0071320 cellular response to cAMP(GO:0071320)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0032472 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0060346 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.3 GO:0003407 neural retina development(GO:0003407)
0.0 0.1 GO:0003065 regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.1 GO:0016265 obsolete death(GO:0016265) dopamine biosynthetic process(GO:0042416)
0.0 0.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.0 GO:2000078 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) regulation of type B pancreatic cell development(GO:2000074) positive regulation of type B pancreatic cell development(GO:2000078)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0031512 motile primary cilium(GO:0031512)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.0 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883)
0.0 0.4 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.5 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.0 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway