Motif ID: BATF

Z-value: 1.957


Transcription factors associated with BATF:

Gene SymbolEntrez IDGene Name
BATF ENSG00000156127.6 BATF



Activity profile for motif BATF.

activity profile for motif BATF


Sorted Z-values histogram for motif BATF

Sorted Z-values for motif BATF



Network of associatons between targets according to the STRING database.



First level regulatory network of BATF

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_21452804 9.614 ENST00000269217.6
LAMA3
laminin, alpha 3
chr18_+_21452964 8.612 ENST00000587184.1
LAMA3
laminin, alpha 3
chr1_-_209824643 5.122 ENST00000391911.1
ENST00000415782.1
LAMB3

laminin, beta 3

chr12_-_52845910 4.851 ENST00000252252.3
KRT6B
keratin 6B
chr18_+_61442629 4.031 ENST00000398019.2
ENST00000540675.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr2_-_113594279 4.005 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B


interleukin 1, beta


chr19_-_51504411 3.814 ENST00000593490.1
KLK8
kallikrein-related peptidase 8
chr1_-_151965048 3.726 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr1_+_153003671 3.180 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr17_-_39769005 3.166 ENST00000301653.4
ENST00000593067.1
KRT16

keratin 16

chr1_-_59043166 2.871 ENST00000371225.2
TACSTD2
tumor-associated calcium signal transducer 2
chr17_-_39677971 2.839 ENST00000393976.2
KRT15
keratin 15
chr6_-_138428613 2.817 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr12_+_13349650 2.648 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1



epithelial membrane protein 1



chr7_+_129932974 2.627 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4





carboxypeptidase A4





chr2_+_102618428 2.542 ENST00000457817.1
IL1R2
interleukin 1 receptor, type II
chr4_-_143226979 2.460 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr12_+_56324756 2.436 ENST00000331886.5
ENST00000555090.1
DGKA

diacylglycerol kinase, alpha 80kDa

chr19_-_39264072 2.347 ENST00000599035.1
ENST00000378626.4
LGALS7

lectin, galactoside-binding, soluble, 7

chr18_+_61445007 2.322 ENST00000447428.1
ENST00000546027.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr19_+_38755203 2.235 ENST00000587090.1
ENST00000454580.3
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_38755042 2.199 ENST00000301244.7
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr1_-_153588765 2.193 ENST00000368701.1
ENST00000344616.2
S100A14

S100 calcium binding protein A14

chr19_+_39279838 2.140 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr11_-_119993979 2.138 ENST00000524816.3
ENST00000525327.1
TRIM29

tripartite motif containing 29

chr2_-_113542063 2.131 ENST00000263339.3
IL1A
interleukin 1, alpha
chr14_-_67859422 2.124 ENST00000556532.1
PLEK2
pleckstrin 2
chr4_-_143227088 2.083 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr9_+_33795533 2.071 ENST00000379405.3
PRSS3
protease, serine, 3
chr16_+_56685796 2.047 ENST00000334346.2
ENST00000562399.1
MT1B

metallothionein 1B

chr4_-_143481822 1.989 ENST00000510812.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr19_-_51487071 1.926 ENST00000391807.1
ENST00000593904.1
KLK7

kallikrein-related peptidase 7

chr3_-_151034734 1.918 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr7_+_55177416 1.907 ENST00000450046.1
ENST00000454757.2
EGFR

epidermal growth factor receptor

chr7_-_24797546 1.906 ENST00000414428.1
ENST00000419307.1
ENST00000342947.3
DFNA5


deafness, autosomal dominant 5


chr7_+_48128194 1.871 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
UPP1


uridine phosphorylase 1


chr1_+_223889285 1.860 ENST00000433674.2
CAPN2
calpain 2, (m/II) large subunit
chr7_+_48128316 1.860 ENST00000341253.4
UPP1
uridine phosphorylase 1
chr17_+_48609903 1.722 ENST00000268933.3
EPN3
epsin 3
chr1_+_183155373 1.689 ENST00000493293.1
ENST00000264144.4
LAMC2

laminin, gamma 2

chr20_-_43883197 1.686 ENST00000338380.2
SLPI
secretory leukocyte peptidase inhibitor
chr2_+_192141611 1.661 ENST00000392316.1
MYO1B
myosin IB
chr4_+_169753156 1.623 ENST00000393726.3
ENST00000507735.1
PALLD

palladin, cytoskeletal associated protein

chr5_-_150948414 1.616 ENST00000261800.5
FAT2
FAT atypical cadherin 2
chr1_+_44398943 1.530 ENST00000372359.5
ENST00000414809.3
ARTN

artemin

chr16_+_56642489 1.505 ENST00000561491.1
MT2A
metallothionein 2A
chr11_-_119993734 1.478 ENST00000533302.1
TRIM29
tripartite motif containing 29
chr16_+_56642041 1.467 ENST00000245185.5
MT2A
metallothionein 2A
chr11_-_33744487 1.387 ENST00000426650.2
CD59
CD59 molecule, complement regulatory protein
chr1_+_46640750 1.385 ENST00000372003.1
TSPAN1
tetraspanin 1
chr2_+_234590556 1.356 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr11_+_101983176 1.352 ENST00000524575.1
YAP1
Yes-associated protein 1
chr15_+_41136216 1.351 ENST00000562057.1
ENST00000344051.4
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr17_-_7493390 1.342 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15


SRY (sex determining region Y)-box 15


chr3_-_127455200 1.312 ENST00000398101.3
MGLL
monoglyceride lipase
chr1_+_158979792 1.300 ENST00000359709.3
ENST00000430894.2
IFI16

interferon, gamma-inducible protein 16

chr15_+_41136586 1.292 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr1_+_86889769 1.291 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr20_+_4667094 1.275 ENST00000424424.1
ENST00000457586.1
PRNP

prion protein

chr1_+_152956549 1.272 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr3_+_30647994 1.261 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr20_+_43803517 1.255 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr17_+_18625336 1.234 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
TRIM16L




tripartite motif containing 16-like




chr11_-_102668879 1.226 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr10_+_88728189 1.205 ENST00000416348.1
ADIRF
adipogenesis regulatory factor
chr2_-_106013400 1.202 ENST00000409807.1
FHL2
four and a half LIM domains 2
chr11_-_33743952 1.196 ENST00000534312.1
CD59
CD59 molecule, complement regulatory protein
chr1_+_158979686 1.190 ENST00000368132.3
ENST00000295809.7
IFI16

interferon, gamma-inducible protein 16

chr2_-_220119280 1.174 ENST00000392088.2
TUBA4A
tubulin, alpha 4a
chr19_-_45909585 1.169 ENST00000593226.1
ENST00000418234.2
PPP1R13L

protein phosphatase 1, regulatory subunit 13 like

chr11_+_394196 1.151 ENST00000331563.2
ENST00000531857.1
PKP3

plakophilin 3

chr11_-_104972158 1.147 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1



CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase



caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr20_+_19867150 1.142 ENST00000255006.6
RIN2
Ras and Rab interactor 2
chr15_+_71145578 1.121 ENST00000544974.2
ENST00000558546.1
LRRC49

leucine rich repeat containing 49

chr3_-_32022733 1.116 ENST00000438237.2
ENST00000396556.2
OSBPL10

oxysterol binding protein-like 10

chr5_+_135394840 1.111 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr12_-_85306594 1.089 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr4_+_47487285 1.082 ENST00000273859.3
ENST00000504445.1
ATP10D

ATPase, class V, type 10D

chr2_-_86094764 1.073 ENST00000393808.3
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr7_-_80551671 1.065 ENST00000419255.2
ENST00000544525.1
SEMA3C

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

chr20_-_56286479 1.058 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr4_+_169842707 1.049 ENST00000503290.1
PALLD
palladin, cytoskeletal associated protein
chr3_+_30648066 1.045 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr1_+_158979680 1.036 ENST00000368131.4
ENST00000340979.6
IFI16

interferon, gamma-inducible protein 16

chr22_+_45148432 1.027 ENST00000389774.2
ENST00000396119.2
ENST00000336963.4
ENST00000356099.6
ENST00000412433.1
ARHGAP8




Rho GTPase activating protein 8




chr6_+_30852130 1.021 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
DDR1



discoidin domain receptor tyrosine kinase 1



chr17_+_73717407 1.013 ENST00000579662.1
ITGB4
integrin, beta 4
chr1_+_233765353 1.009 ENST00000366620.1
KCNK1
potassium channel, subfamily K, member 1
chr6_-_46703430 0.992 ENST00000537365.1
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr6_+_121756809 0.992 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr1_-_153521597 0.988 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr4_-_10023095 0.974 ENST00000264784.3
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr11_-_6341844 0.964 ENST00000303927.3
PRKCDBP
protein kinase C, delta binding protein
chr9_+_706842 0.948 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr11_+_35198118 0.923 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44



CD44 molecule (Indian blood group)



chr16_+_57662138 0.922 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
GPR56





G protein-coupled receptor 56





chr6_-_56507586 0.920 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
DST




dystonin




chr18_+_61637159 0.911 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
SERPINB8




serpin peptidase inhibitor, clade B (ovalbumin), member 8




chr2_+_234621551 0.903 ENST00000373414.3
ENST00000608381.1
UGT1A5
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A5
UDP glucuronosyltransferase 1 family, polypeptide A8
chr2_+_102615416 0.896 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr2_-_85637459 0.893 ENST00000409921.1
CAPG
capping protein (actin filament), gelsolin-like
chr5_-_175843524 0.880 ENST00000502877.1
CLTB
clathrin, light chain B
chr4_-_36246060 0.875 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_+_74735102 0.871 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr19_-_51523412 0.867 ENST00000391805.1
ENST00000599077.1
KLK10

kallikrein-related peptidase 10

chr3_-_49395705 0.864 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr19_-_44285401 0.863 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_-_152009460 0.846 ENST00000271638.2
S100A11
S100 calcium binding protein A11
chr20_+_4666882 0.843 ENST00000379440.4
ENST00000430350.2
PRNP

prion protein

chr11_-_2950642 0.838 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr15_+_52155001 0.833 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr3_+_105085734 0.828 ENST00000306107.5
ALCAM
activated leukocyte cell adhesion molecule
chr5_+_125695805 0.814 ENST00000513040.1
GRAMD3
GRAM domain containing 3
chr1_-_153113927 0.813 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr2_+_201450591 0.812 ENST00000374700.2
AOX1
aldehyde oxidase 1
chr16_+_56691838 0.802 ENST00000394501.2
MT1F
metallothionein 1F
chr16_+_57662419 0.798 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56






G protein-coupled receptor 56






chr17_+_48712206 0.792 ENST00000427699.1
ENST00000285238.8
ABCC3

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

chr9_+_75766652 0.789 ENST00000257497.6
ANXA1
annexin A1
chr9_+_130911770 0.782 ENST00000372998.1
LCN2
lipocalin 2
chr2_-_85641162 0.781 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
CAPG


capping protein (actin filament), gelsolin-like


chr2_-_151344172 0.770 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3


Rho family GTPase 3


chr16_+_56691606 0.764 ENST00000334350.6
MT1F
metallothionein 1F
chr16_+_56691911 0.760 ENST00000568475.1
MT1F
metallothionein 1F
chr5_-_175843569 0.755 ENST00000310418.4
ENST00000345807.2
CLTB

clathrin, light chain B

chr11_+_131240373 0.755 ENST00000374791.3
ENST00000436745.1
NTM

neurotrimin

chr11_-_65667997 0.748 ENST00000312562.2
ENST00000534222.1
FOSL1

FOS-like antigen 1

chr11_+_5710919 0.747 ENST00000379965.3
ENST00000425490.1
TRIM22

tripartite motif containing 22

chr3_-_149095652 0.740 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr1_-_153521714 0.727 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr18_+_56338750 0.717 ENST00000345724.3
MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr6_-_32784687 0.715 ENST00000447394.1
ENST00000438763.2
HLA-DOB

major histocompatibility complex, class II, DO beta

chr8_-_145016692 0.710 ENST00000357649.2
PLEC
plectin
chr3_-_48632593 0.709 ENST00000454817.1
ENST00000328333.8
COL7A1

collagen, type VII, alpha 1

chr12_+_9144626 0.707 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr22_+_31488433 0.705 ENST00000455608.1
SMTN
smoothelin
chr9_+_130911723 0.703 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2


lipocalin 2


chr7_-_87856303 0.702 ENST00000394641.3
SRI
sorcin
chr16_-_11680759 0.689 ENST00000571459.1
ENST00000570798.1
ENST00000572255.1
ENST00000574763.1
ENST00000574703.1
ENST00000571277.1
ENST00000381810.3
LITAF






lipopolysaccharide-induced TNF factor






chr14_+_58666824 0.689 ENST00000254286.4
ACTR10
actin-related protein 10 homolog (S. cerevisiae)
chr16_-_84538218 0.689 ENST00000562447.1
ENST00000565765.1
ENST00000535580.1
ENST00000343629.6
TLDC1



TBC/LysM-associated domain containing 1



chr17_+_73717551 0.687 ENST00000450894.3
ITGB4
integrin, beta 4
chr1_+_158985457 0.679 ENST00000567661.1
ENST00000474473.1
IFI16

interferon, gamma-inducible protein 16

chr12_+_56324933 0.674 ENST00000549629.1
ENST00000555218.1
DGKA

diacylglycerol kinase, alpha 80kDa

chr5_+_66124590 0.674 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4


microtubule associated serine/threonine kinase family member 4


chr19_-_51523275 0.670 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr18_+_56338618 0.669 ENST00000348428.3
MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr19_-_45982076 0.667 ENST00000423698.2
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr12_-_15104040 0.667 ENST00000541644.1
ENST00000545895.1
ARHGDIB

Rho GDP dissociation inhibitor (GDI) beta

chr11_-_33744256 0.666 ENST00000415002.2
ENST00000437761.2
ENST00000445143.2
CD59


CD59 molecule, complement regulatory protein


chr11_+_121163466 0.659 ENST00000527762.1
ENST00000534230.1
ENST00000392789.2
SC5D


sterol-C5-desaturase


chr1_+_201252580 0.655 ENST00000367324.3
ENST00000263946.3
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chr6_-_2842087 0.654 ENST00000537185.1
SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr20_-_56265680 0.653 ENST00000414037.1
PMEPA1
prostate transmembrane protein, androgen induced 1
chr14_+_55590646 0.651 ENST00000553493.1
LGALS3
lectin, galactoside-binding, soluble, 3
chr1_+_26605618 0.636 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr1_-_205290865 0.632 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr18_-_33702078 0.630 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr11_-_6341724 0.626 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr8_-_145025044 0.618 ENST00000322810.4
PLEC
plectin
chr16_-_10652993 0.617 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr11_-_65667884 0.611 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr8_-_42065187 0.603 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT


plasminogen activator, tissue


chr2_+_113763031 0.602 ENST00000259211.6
IL36A
interleukin 36, alpha
chr1_-_169337176 0.596 ENST00000472647.1
ENST00000367811.3
NME7

NME/NM23 family member 7

chr19_-_42463418 0.594 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
RABAC1



Rab acceptor 1 (prenylated)



chr15_-_71146480 0.594 ENST00000299213.8
LARP6
La ribonucleoprotein domain family, member 6
chr9_-_21335356 0.593 ENST00000359039.4
KLHL9
kelch-like family member 9
chr14_-_102771462 0.591 ENST00000522874.1
MOK
MOK protein kinase
chr3_+_158787041 0.591 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr3_+_36421826 0.590 ENST00000273183.3
STAC
SH3 and cysteine rich domain
chr17_+_1936687 0.587 ENST00000570477.1
DPH1
diphthamide biosynthesis 1
chr11_-_104817919 0.579 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr6_-_84140757 0.579 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1


malic enzyme 1, NADP(+)-dependent, cytosolic


chr6_-_2842219 0.571 ENST00000380739.5
SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr14_+_94577074 0.568 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27








interferon, alpha-inducible protein 27








chr5_+_36608422 0.561 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_+_134528635 0.560 ENST00000445569.2
CALD1
caldesmon 1
chr21_-_27542972 0.556 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
APP






amyloid beta (A4) precursor protein






chr3_-_46735132 0.551 ENST00000415953.1
ALS2CL
ALS2 C-terminal like
chr13_+_78109804 0.546 ENST00000535157.1
SCEL
sciellin
chr13_+_78109884 0.544 ENST00000377246.3
ENST00000349847.3
SCEL

sciellin

chr12_-_10573149 0.544 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
KLRC3


killer cell lectin-like receptor subfamily C, member 3


chr19_+_6531010 0.539 ENST00000245817.3
TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
chr22_+_23046750 0.537 ENST00000390307.2
IGLV3-22
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr7_+_142457315 0.536 ENST00000486171.1
ENST00000311737.7
PRSS1

protease, serine, 1 (trypsin 1)

chr12_+_75874460 0.534 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr1_-_6420737 0.531 ENST00000541130.1
ENST00000377845.3
ACOT7

acyl-CoA thioesterase 7

chr12_-_33049690 0.529 ENST00000070846.6
ENST00000340811.4
PKP2

plakophilin 2

chrX_-_153141302 0.528 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1CAM




L1 cell adhesion molecule




chr9_+_71819927 0.523 ENST00000535702.1
TJP2
tight junction protein 2
chr17_+_74381343 0.523 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr17_-_38657849 0.520 ENST00000254051.6
TNS4
tensin 4
chr1_+_26503894 0.515 ENST00000361530.6
ENST00000374253.5
CNKSR1

connector enhancer of kinase suppressor of Ras 1

chr15_-_72523924 0.512 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
PKM



pyruvate kinase, muscle



chr1_+_26606608 0.511 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr1_+_169337172 0.511 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
BLZF1



basic leucine zipper nuclear factor 1



chr2_+_234545092 0.506 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr21_+_42798094 0.504 ENST00000398598.3
ENST00000455164.2
ENST00000424365.1
MX1


myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)


chr11_-_108408895 0.500 ENST00000443411.1
ENST00000533052.1
EXPH5

exophilin 5


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.1 GO:0010193 response to ozone(GO:0010193)
1.3 3.8 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
1.0 3.0 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.0 28.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.9 3.7 GO:0046108 uridine metabolic process(GO:0046108)
0.8 2.3 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.6 1.9 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.5 2.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.5 1.5 GO:0009635 response to herbicide(GO:0009635)
0.4 1.3 GO:0048627 myoblast development(GO:0048627)
0.4 1.5 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.4 1.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.4 1.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.3 1.4 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.3 2.2 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.3 1.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 1.0 GO:0051503 purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503)
0.2 1.5 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 1.6 GO:0051552 flavone metabolic process(GO:0051552)
0.2 1.4 GO:0060242 contact inhibition(GO:0060242)
0.2 0.7 GO:0034205 beta-amyloid formation(GO:0034205)
0.2 1.3 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.9 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.2 1.0 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.2 6.0 GO:0031424 keratinization(GO:0031424)
0.2 1.4 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.2 1.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 0.7 GO:0033986 response to methanol(GO:0033986) response to chromate(GO:0046687)
0.2 0.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.6 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 0.8 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2 0.5 GO:0046102 nicotinamide riboside catabolic process(GO:0006738) inosine metabolic process(GO:0046102) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.2 4.7 GO:0007398 ectoderm development(GO:0007398)
0.2 0.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.2 0.5 GO:0060340 pericardium morphogenesis(GO:0003344) optic cup formation involved in camera-type eye development(GO:0003408) diencephalon morphogenesis(GO:0048852) positive regulation of type I interferon-mediated signaling pathway(GO:0060340) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.1 0.6 GO:0031223 mechanosensory behavior(GO:0007638) response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223) malate-aspartate shuttle(GO:0043490)
0.1 2.8 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.4 GO:0016081 synaptic vesicle docking(GO:0016081) positive regulation of neurotransmitter transport(GO:0051590)
0.1 3.9 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.1 0.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 15.5 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.6 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.5 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 0.4 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 1.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.7 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.1 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 0.5 GO:0045103 intermediate filament-based process(GO:0045103)
0.1 0.5 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.4 GO:0071418 uroporphyrinogen III biosynthetic process(GO:0006780) cellular response to amine stimulus(GO:0071418)
0.1 0.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 1.1 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.1 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.4 GO:0051170 nuclear import(GO:0051170)
0.1 0.6 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.2 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.1 0.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.1 2.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.1 GO:0060462 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.1 0.2 GO:1904742 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) regulation of telomeric DNA binding(GO:1904742) positive regulation of telomeric DNA binding(GO:1904744)
0.1 0.4 GO:0070295 renal water absorption(GO:0070295)
0.1 0.3 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.6 GO:0019359 nicotinamide nucleotide biosynthetic process(GO:0019359)
0.1 0.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 3.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.5 GO:0046051 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.1 0.2 GO:0030091 protein repair(GO:0030091)
0.1 0.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.3 GO:0060414 aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.1 0.2 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.1 0.2 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.1 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.5 GO:0060119 auditory receptor cell development(GO:0060117) inner ear receptor cell development(GO:0060119)
0.1 0.3 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 1.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.7 GO:0070206 protein trimerization(GO:0070206)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848)
0.0 0.1 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.0 GO:0034014 response to triglyceride(GO:0034014)
0.0 0.8 GO:0042730 fibrinolysis(GO:0042730)
0.0 1.0 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0 0.3 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 8.0 GO:0008544 epidermis development(GO:0008544)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 1.1 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.2 GO:0060346 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.5 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0046132 pyrimidine ribonucleoside biosynthetic process(GO:0046132)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 1.0 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.1 GO:0070365 hepatocyte differentiation(GO:0070365) cellular response to oleic acid(GO:0071400)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.3 GO:0051384 response to glucocorticoid(GO:0051384)
0.0 0.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.1 GO:0090085 protein K29-linked ubiquitination(GO:0035519) regulation of protein deubiquitination(GO:0090085)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 2.6 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.8 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 2.7 GO:0016573 histone acetylation(GO:0016573)
0.0 0.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.3 GO:0034661 ncRNA catabolic process(GO:0034661)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0 0.1 GO:1902414 protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.8 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.3 GO:0008272 sulfate transport(GO:0008272)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0034776 negative regulation of sodium:proton antiporter activity(GO:0032416) response to histamine(GO:0034776) negative regulation of dopamine receptor signaling pathway(GO:0060160) negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.2 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0032527 retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527)
0.0 0.2 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.1 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.4 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 1.7 GO:0009206 ATP biosynthetic process(GO:0006754) ribonucleoside triphosphate biosynthetic process(GO:0009201) purine ribonucleoside triphosphate biosynthetic process(GO:0009206)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.2 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.0 1.0 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 1.5 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.0 GO:0007418 ventral midline development(GO:0007418)
0.0 1.4 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.0 GO:0009750 response to fructose(GO:0009750)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.3 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.6 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.2 GO:0051322 anaphase(GO:0051322)
0.0 0.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 1.0 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.8 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.3 GO:0030837 negative regulation of actin filament polymerization(GO:0030837)
0.0 0.1 GO:0032387 negative regulation of intracellular transport(GO:0032387)
0.0 0.1 GO:2000648 positive regulation of stem cell proliferation(GO:2000648)
0.0 0.1 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0005610 laminin-5 complex(GO:0005610)
1.2 18.2 GO:0005606 laminin-1 complex(GO:0005606)
0.5 3.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 2.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.3 1.9 GO:0070435 Shc-EGFR complex(GO:0070435)
0.3 1.4 GO:0032449 CBM complex(GO:0032449)
0.3 5.5 GO:0030057 desmosome(GO:0030057)
0.3 7.6 GO:0001533 cornified envelope(GO:0001533)
0.2 1.2 GO:0005916 fascia adherens(GO:0005916)
0.2 0.7 GO:0014802 terminal cisterna(GO:0014802) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.0 GO:0051233 spindle midzone(GO:0051233)
0.1 5.0 GO:0045095 keratin filament(GO:0045095)
0.1 0.1 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.1 2.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.8 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.1 1.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 1.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.4 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.9 GO:0031430 M band(GO:0031430)
0.1 0.7 GO:0005869 dynactin complex(GO:0005869)
0.1 3.9 GO:0005882 intermediate filament(GO:0005882)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.7 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.1 GO:0070938 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.1 1.2 GO:0043205 fibril(GO:0043205)
0.1 0.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.2 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0031975 organelle envelope(GO:0031967) envelope(GO:0031975)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.2 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0019861 obsolete flagellum(GO:0019861)
0.0 1.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0032420 stereocilium(GO:0032420)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:0019867 outer membrane(GO:0019867)
0.0 1.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.5 GO:0070161 anchoring junction(GO:0070161)
0.0 0.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.0 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.5 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.9 3.7 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.7 3.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.6 2.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.5 6.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.5 2.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.7 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 1.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.2 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 19.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 3.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.6 GO:0004473 malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 0.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) exoribonuclease II activity(GO:0008859)
0.1 0.6 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 2.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 1.0 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 1.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.4 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 1.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.7 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 1.0 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.1 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.4 GO:0019863 IgE binding(GO:0019863)
0.1 1.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 3.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0016595 glutamate binding(GO:0016595)
0.1 8.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0017096 acetylserotonin O-methyltransferase activity(GO:0017096)
0.1 0.3 GO:0047026 androsterone dehydrogenase (A-specific) activity(GO:0047026)
0.1 1.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.1 0.2 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.5 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 1.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0050833 pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 1.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.5 GO:0002020 protease binding(GO:0002020)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0001846 opsonin binding(GO:0001846)
0.0 1.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.1 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 1.1 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.9 GO:0043621 protein self-association(GO:0043621)
0.0 7.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.5 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.9 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 27.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 1.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.4 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0070891 peptidoglycan receptor activity(GO:0016019) lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 2.2 GO:0003774 motor activity(GO:0003774)
0.0 1.1 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0032451 demethylase activity(GO:0032451)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883)
0.0 0.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.0 GO:0050062 long-chain-fatty-acyl-CoA reductase activity(GO:0050062)
0.0 0.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.0 GO:0016635 succinate dehydrogenase activity(GO:0000104) oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.0 GO:0004461 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) lactose synthase activity(GO:0004461)
0.0 0.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.0 GO:0017129 triglyceride binding(GO:0017129)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.7 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.3 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.1 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.4 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.3 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.